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CO Poisoning

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https://www.readbyqxmd.com/read/28812383/evaluation-of-relationship-between-coronary-artery-status-evaluated-by-coronary-computed-tomography-angiography-and-development-of-cardiomyopathy-in-carbon-monoxide-poisoned-patients-with-myocardial-injury-a-prospective-observational-study
#1
Yong Sung Cha, Hyun Kim, Yoonsuk Lee, Woocheol Kwon, Jung-Woo Son, Hyun Youk, Hyung Il Kim, Oh Hyun Kim, Kyung Hye Park, Kyoung-Chul Cha, Kang Hyun Lee, Sung Oh Hwang
OBJECTIVES: Whether coronary artery changes are a main mechanism in the development of carbon monoxide (CO)-induced cardiomyopathy remains unknown. We investigated the effects of coronary artery stenosis on the presence or patterns of cardiomyopathy in CO-poisoned patients with myocardial injury defined as elevation of troponin I. MATERIALS AND METHODS: This prospective observational study collected data from consecutive patients who were diagnosed with CO poisoning and myocardial injury during the 24-month study period...
August 16, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28812367/the-usefulness-of-diffusion-weighted-magnetic-resonance-imaging-performed-in-the-acute-phase-as-an-early-predictor-of-delayed-neuropsychiatric-sequelae-in-acute-carbon-monoxide-poisoning
#2
Y S Kim, Y S Cha, M S Kim, H J Kim, Y S Lee, H Youk, H I Kim, O H Kim, K-C Cha, H Kim, K H Lee, S O Hwang
Delayed onset of neuropsychiatric symptoms after apparent recovery from acute carbon monoxide (CO) poisoning has been described as delayed neuropsychiatric sequelae (DNS). No previous study has determined whether early use of diffusion-weighted magnetic resonance imaging (DWI) can predict which patients will develop DNS in the acute CO poisoning. This retrospective observational study was performed on adult patients with acute CO poisoning consecutively treated over a 17-month period. All included patients with acute CO poisoning underwent DWI to evaluate brain injury within 72 h after CO exposure...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28807985/inhaled-carbon-monoxide-from-toxin-to-therapy
#3
Dean R Hess
Carbon monoxide (CO) is usually recognized as a toxic gas that can be used to assess lung function in the pulmonary function laboratory. The toxicity of CO relates to its high affinity for hemoglobin and other heme molecules, producing carboxyhemoglobin (HbCO). Despite that blood HbCO levels are commonly measured in patients with CO poisoning, the clinical presentation often does not correlate with the HbCO level, and clinical improvement in the patient's condition does not correlate with HbCO clearance. In patients with CO poisoning, administration of 100% O2 is standard practice...
August 14, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28806029/atrial-fibrillation-induced-by-carbon-monoxide-poisoning-and-successful-treatment-with-hyperbaric-oxygen
#4
Maheedhar Gedela, Nathan Y Weltman, Naga Sushma Chavvakula, Paul L Carpenter, Tamera Sturm
Carbon monoxide (CO) intoxication is one of the major public health hazards which may go unnoticed as this is a colorless, odorless and tasteless gas. The manifestations of the CO poisoning are far-reaching. Although CO affects almost every organ in the body, cerebral and myocardial involvement are predominant due to the hypoxia-induced cellular damage. The mainstay treatment is providing high-flow oxygen and in some instances hyperbaric oxygen therapy. In the literature, there have been few cases of CO poisoning-induced atrial fibrillation (AF) reported...
July 2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28795814/anion-exchange-membrane-fuel-cells-with-improved-co2-tolerance-impact-of-chemically-induced-bicarbonate-ion-consumption
#5
Yu Katayama, Kosuke Yamauchi, Kohei Hayashi, Takeou Okanishi, Hiroki Muroyama, Toshiaki Matsui, Yuuki Kikkawa, Takayuki Negishi, Shin Watanabe, Takenori Isomura, Koichi Eguchi
Over the last few decades, owing to the significant development of anion exchange membranes, increasing efforts have been devoted the realization of anion exchange membrane fuel cells (AEMFCs) that operate with the supply of hydrogen generated on-site. In this paper, ammonia was selected as a hydrogen source, following which the effect of conceivable impurities, unreacted NH3 and atmospheric CO2, on the performance of AEMFCs was established. As expected, we show that these impurities worsen the performance of AEMFCs significantly...
August 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28783889/comparison-of-normobaric-vs-hyperbaric-oxygen-in-the-relief-of-carbon-monoxide-headache-pain
#6
Neil B Hampson, Tarik Ocak
BACKGROUND: Headache is the most common symptom in carbon monoxide (CO) poisoning. While the mechanism of CO-induced headache is not well defined, it is felt that cerebral vasodilation plays a role. Clinical experience has demonstrated oxygen breathing is effective in resolving CO headache. However, the effectiveness of normobaric oxygen has never been compared to hyperbaric oxygen in this regard. METHODS: A 2016 paper by Ocak, et al. reported the response of CO headache pain severity to four hours of normobaric oxygen breathing in 82 patients using a 0-10 analog scale...
July 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28780827/-imaging-diagnosis-of-95-cases-of-moderate-and-severe-acute-carbon-monoxide-poisoning
#7
N N Hao, C Tian, K X Lian, T Han, S Jin
Objective: To explore the difference of radiological imaging features of delayed encephalopathy after carbon monoxide poisoning (DECMP) and acute carbon monoxide poisoning (ACMP) , and the correlation between the imaging findings and clinical prognosis of the disease. Methods: The correlation between imaging findings and clinical manifestations and prognosis of 95 patients with moderate and severe acute carbon monoxide poisoning were retrospectively analyzed. In the above 95 cases, there were 62 cases of ACMP and 33 cases of DEACMP...
June 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/28777908/carboxyhemoglobin-half-life-during-hyperbaric-oxygen-in-a-patient-with-lung-dysfunction-a-case-report
#8
Lindell K Weaver, Kayla Deru
INTRODUCTION: The carboxyhemoglobin half-life (COHb t1/2) during hyperbaric oxygen (HBO₂) is often quoted as 23 minutes, derived from the average of two adult male volunteers breathing HBO₂ at 3 atmospheres absolute (ATA). However, the mean COHb t1/2 of 12 male volunteer smokers was 26.3 minutes at 1.58 ATA and in 12 non-intubated carbon monoxide (CO) poisoned patients treated at 3 ATA, was 43 minutes. CASE REPORT: An 81-year old male, poisoned by an improperly ventilated natural gas heater, was intubated for coma, then treated with HBO₂...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777902/effects-of-hyperbaric-oxygen-on-hippocampal-neuronal-apoptosis-in-rats-with-acute-carbon-monoxide-poisoning
#9
Li Xue, Wen-Lan Wang, Ya Li, Xu Gong, Jun-Xiang Bao, Hai-Jun Zhang, Xiao-Ping Xie, Yao-Ming Chang, Jin-Sheng Li
INTRODUCTION: Acute carbon monoxide (CO) poisoning causes serious health problems such as neuropsychological sequelae. This study aimed to investigate neuronal apoptosis and the effects of hyperbaric oxygen (HBO₂) on different regions of the rat hippocampus after CO poisoning. METHODS: 90 mature male Sprague Dawley rats were randomly divided into three groups: the normal control group (NC group), the acute carbon monoxide-poisoned group (CO group) and the hyperbaric oxygen treatment group (HBO₂ group)...
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777898/another-perspective-on-acep-policy-on-critical-issues-in-carbon-monoxide-poisoning-invited-commentary
#10
Neil B Hampson, Richard E Moon, Lindell K Weaver
The American College of Emergency Physicians (ACEP) recently published its official policy on the evaluation and management of patients with acute carbon monoxide (CO) poisoning [1], an update of the policy previously published in 2008. Three questions regarding CO poisoning were posed to a 30-person ACEP subcommittee, which employed a comprehensive literature review to attempt to draw conclusions. While this is a major step forward, we feel that their conclusions warrant comment.
March 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777878/a-multi-analyte-approach-to-help-in-assessing-the-severity-of-acute-poisonings-development-and-validation-of-a-fast-lc-ms-ms-quantification-approach-for-45-drugs-and-relevant-metabolites-with-one-point-calibration
#11
Julian A Michely, Hans H Maurer
In emergency toxicology, diagnosis, monitoring of the efficiency of detoxification, and estimating the prognosis of acute poisonings are important tasks. Comprehensive screening and quantification of relevant substances by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS) help in assessing the severity of most acute poisonings. Turnaround time for such analyses must be short enough for having impact on clinical decisions. Therefore, a multi-analyte LC-MS/MS approach with a 5-min gradient was developed and validated for 45 drugs and active metabolites as complement to an existing GC-MS approach using the same liquid-liquid extraction...
August 4, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28777513/rna-sequencing-analysis-reveals-new-findings-of-hyperbaric-oxygen-treatment-on-rats-with-acute-carbon-monoxide-poisoning
#12
Wenlan Wang, Li Xue, Ya Li, Rong Li, Xiaoping Xie, Junxiang Bao, Chunxu Hai, Jinsheng Li
OBJECTIVE: To elucidate the altered gene network in the brains of carbon monoxide (CO) poisoned rats after treatment with hyperbaric oxygen (HBO₂). METHODS: RNA sequencing (RNA-seq) analysis was performed to examine differentially expressed genes (DEGs) in brain tissue samples from nine male rats: a normal control group; a CO poisoning group; and an HBO₂ treatment group (three rats/group). Reverse transcription polymerase chain reaction (RT-PCR) and real-time quantitative PCR were used for validation of the DEGs in another 18 male rats (six rats/group)...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28777512/carbon-monoxide-poisoning-in-utah-1996-2013
#13
Lindell K Weaver, Kayla Deru, Susan Churchill, Joshua Legler, Greg Snow, Todd Grey
INTRODUCTION: The true incidence of carbon monoxide (CO) poisoning is not clearly known, but a description of possible trends could aid in prevention. METHODS: Investigators searched Utah state databases for emergency department (ED) visits and admissions for CO poisoning and medical examiner records for CO-related fatalities. RESULTS: From 1996-2013, 7,590 individuals were diagnosed with CO poisoning: 6,469 were treated/ released from EDs; 596 were admitted; 525 died...
November 2016: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28768080/garage-carbon-monoxide-levels-from-sources-commonly-used-in-intentional-poisoning
#14
Neil B Hampson, James R Holm, Todd G Courtney
BACKGROUND: The incidence of intentional carbon monoxide (CO) poisoning is believed to have declined due to strict federal CO emissions standards for motor vehicles and the uniform application of catalytic converters (CC). We sought to compare ambient CO levels produced by automobiles with and without catalytic converters in a residential garage, as well as from other CO sources commonly used for intentional poisoning. METHODS: CO levels were measured inside a freestanding 73 m3 one-car garage...
January 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/28763389/improving-outreach-and-surveillance-efforts-following-a-large-scale-carbon-monoxide-poisoning-in-wisconsin
#15
Paul D Creswell, Christy M Vogt, Ryan J Wozniak, Jenny Camponeschi, Mark A Werner, Jonathan G Meiman
OBJECTIVE: In December 2014, the largest carbon monoxide (CO) poisoning in Wisconsin's history occurred at an ice arena. Following this event, the Wisconsin Environmental Public Health Tracking (WI EPHT) Program sought to improve outreach and surveillance efforts. METHODS: WI EPHT designed and distributed educational materials on CO poisoning prevention and surveyed stakeholders to gauge the effectiveness of outreach efforts. To enhance surveillance, WI EPHT utilized data from the Wisconsin Poison Center (WPC) to generate real-time alerts of anomalous numbers of CO-related calls...
September 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28763382/economic-valuation-of-selected-illnesses-in-environmental-public-health-tracking
#16
Ying Zhou, Tursynbek Nurmagambetov, Matthew McCord, Wan-Hsiang Hsu
BACKGROUND: In benefit-cost analysis of public health programs, health outcomes need to be assigned monetary values so that different health endpoints can be compared and improvement in health can be compared with cost of the program. There are 2 major approaches for estimating economic value of illnesses: willingness to pay (WTP) and cost of illness (COI). In this study, we compared these 2 approaches and summarized valuation estimates for 3 health endpoints included in the Centers for Disease Control and Prevention's National Environmental Public Health Tracking Network-asthma, carbon monoxide (CO) poisoning, and lead poisoning...
September 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28762572/promoting-effect-of-ni-oh-2-on-palladium-nanocrystals-leads-to-greatly-improved-operation-durability-for-electrocatalytic-ethanol-oxidation-in-alkaline-solution
#17
Wenjing Huang, Xian-Yin Ma, Han Wang, Renfei Feng, Jigang Zhou, Paul N Duchesne, Peng Zhang, Fengjiao Chen, Na Han, Feipeng Zhao, Junhua Zhou, Wen-Bin Cai, Yanguang Li
Most electrocatalysts for the ethanol oxidation reaction suffer from extremely limited operational durability and poor selectivity toward the CC bond cleavage. In spite of tremendous efforts over the past several decades, little progress has been made in this regard. This study reports the remarkable promoting effect of Ni(OH)2 on Pd nanocrystals for electrocatalytic ethanol oxidation reaction in alkaline solution. A hybrid electrocatalyst consisting of intimately mixed nanosized Pd particles, defective Ni(OH)2 nanoflakes, and a graphene support is prepared via a two-step solution method...
August 1, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28762278/co-ingested-alcohol-and-the-timing-of-deliberate-self-poisonings
#18
Kate M Chitty, Katharine Kirby, Nicholas J Osborne, Geoffrey K Isbister, Nicholas A Buckley
OBJECTIVE: Investigating diurnal variation in the timing of suicidal behaviours offers opportunity to better understand its various proximal risk factors. Acute use of alcohol is a potent proximal risk factor for suicidal behaviour, though the nature of this risk is poorly understood. The aim of this study was to compare the diurnal variation in time of poison ingestion between deliberate self-poisonings that involve alcohol versus those that do not. METHODS: A retrospective analysis of consecutive presentations to a toxicology service following deliberate self-poisoning, 1996-2016...
July 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28753048/initial-diffusion-weighted-mri-and-long-term-neurologic-outcomes-in-charcoal-burning-carbon-monoxide-poisoning
#19
J M Moon, B J Chun, B H Baek, Y J Hong
CONTEXT: This study assessed the results of diffusion-weighted imaging (DWI) at presentation for acute charcoal-burning carbon monoxide (CO) poisoning and investigated whether the initial DWI results can predict long-term neurologic outcomes. METHODS: The study included 128 patients who suffered from CO poisoning after burning charcoal and underwent DWI. These patients were divided into two groups based on imaging results: a normal DWI group and an abnormal DWI group...
July 28, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28752154/epidemiology-pathophysiology-clinical-evaluation-and-treatment-of-carbon-monoxide-poisoning-in-child-infant-and-fetus
#20
REVIEW
Atilla Alp Gozubuyuk, Huseyin Dag, Alper Kacar, Yakup Karakurt, Vefik Arica
Carbon monoxide (CO) poisoning is one of the most common types of poisoning causing death worldwide. In our country, it occurs particularly during winter as a result of leak from stove or water heater, or as result of inhalation during a fire. Although most poisonings occur accidentally, some cases are suicide attempt. As CO is a substance that is not visible and has no taste or smell and is therefore difficult to detect, the gas can be a "silent killer" that is not noticed until effects develop. CO reacts with oxygen, creating carboxy hemoglobin (COHb), which leads to tissue hypoxia...
2017: Northern Clinics of Istanbul
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