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CO Poisoning

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https://www.readbyqxmd.com/read/28195459/ternary-pt9rhfex-nanoscale-alloys-as-highly-efficient-catalysts-with-enhanced-activity-and-excellent-co-poisoning-tolerance-for-ethanol-oxidation
#1
Peng Wang, Shibin Yin, Ying Wen, Zhiqun Tian, Ningzhang Wang, Julian Key, Shuangbao Wang, Pei Kang Shen
To address the problems of high cost and poor stability of anode catalysts in direct ethanol fuel cells (DEFCs), ternary nanoparticles Pt9RhFex (x = 1, 3, 5, 7 and 9) supported on carbon powder (XC-72R) have been synthesized via a facile method involving reduction by sodium borohydride followed by thermal annealing in N2 at ambient pressure. The catalysts are physically characterized by XRD, STEM, and XPS, their catalytic performance for ethanol oxidation reaction (EOR) is evaluated by different electrochemical methods...
February 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28167472/mri-and-clinical-manifestations-of-delayed-encephalopathy-after-carbon-monoxide-poisoning
#2
Xiahong Wang, Zhenyu Li, Jacqueline Berglass, Wenlong He, Jianmin Zhao, Min Zhang, Chongyang Gao, Caixia Zhang, Huimin Zhang, Xuewei Yi
To explore the relationship between the clinical manifestations and functional magnetic resonance images of delayed encephalopathy after carbon monoxide intoxication. Six patients received the MRI were diagnosed with delayed encephalopathy after carbon monoxide (CO) poisoning. Clinical manifestations were observed in each patient. MRI revealed multiple lesions. The majority of the lesions were located in the globus pallidus, sub cortical white matter, and basal ganglia. The cognitive injury, akinetic mutism, fecal and uroclepsia, forced crying, forced laughing and extra pyramidal syndromes such as chorea and parkinsonism were manifested in clinic...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28163920/risk-factors-for-the-delayed-onset-of-neuropsychologic-sequelae-following-carbon-monoxide-poisoning
#3
Takeshi Kitamoto, Masanobu Tsuda, Masaki Kato, Fukuki Saito, Yoshito Kamijo, Toshihiko Kinoshita
AIM: Carbon monoxide (CO) poisoning often manifests delayed neuropsychological sequelae. The risks and preventive factors for the development of delayed neuropsychological sequelae are controversial at present. The purpose of this retrospective study was to assess the risk factors for this condition. METHOD: We studied 81 patients with CO poisoning admitted to the Critical Care and Emergency Medicine Center at the Kansai Medical University from 2006 to 2012. All patients (64 males and 17 females; average age, 45...
October 2016: Acute Med Surg
https://www.readbyqxmd.com/read/28158885/breaking-bad-delirium-methamphetamine-and-boric-acid-toxicity-with-hallucinations-and-pseudosepsis
#4
Kayla Johnson, Joanna L Stollings, E Wesley Ely
OBJECTIVES: A 30-year-old patient presented with hallucinations and profound shock. He was initially misdiagnosed as having severe sepsis; once ingestions were considered, he was diagnosed as potentially having arsenic toxicity. SUMMARY: The clinical story reveals many instructional lessons that could aid in the evaluation and management of future patients. This man presented with large amounts of blue crystals around his nose and lips from inhaling and eating boric acid (an ant poison) so he could, as he put it, kill the ants "pouring into my mouth and nose and up into my brain...
February 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28151889/early-white-matter-injuries-in-patients-with-acute-carbon-monoxide-intoxication-a-tract-specific-diffusion-kurtosis-imaging-study-and-strobe-compliant-article
#5
Ping-Huei Tsai, Ming-Chung Chou, Shih-Wei Chiang, Hsiao-Wen Chung, Hua-Shan Liu, Hung-Wen Kao, Cheng-Yu Chen
Evaluation of acute white matter injuries caused by carbon monoxide (CO) poisoning can be limited by conventional magnetic resonance (MR) imaging. We aim to evaluate the feasibility of diffusion kurtosis imaging (DKI) for early detection of white matter alterations in patients with acute CO intoxication.A total of 30 subjects including 15 acute CO patients and 15 age- and sex-matched healthy volunteers were enrolled in this study. MR examinations were performed on a 3T MR scanner within 8 days after CO intoxication...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28133917/electrocatalytic-co2-reduction-to-formate-at-low-overpotentials-on-electrodeposited-pd-films-stabilized-performance-by-suppression-of-co-formation
#6
Fengling Zhou, Haitao Li, Maxime Fournier, Douglas Macfarlane
Palladium (Pd) nanoparticles have been proven to effectively catalytic CO2 reduction. However CO, one of the most important products in the CO2 reduction sequence, has strong affinity for the Pd surface and rapidly poisons the catalytic site. In this research, an electrodeposited Pd film is shown to exhibit high activity for CO2 reduction to formate with suppression of CO formation at low overpotentials. The substrates, electrodeposition process and the post treatment of the Pd films significantly affect the CO2 reduction pathway...
January 29, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28129435/presence-of-alcohol-cocaine-and-other-drugs-in-suicide-and-motor-vehicle-crash-decedents-ages-18-to-54
#7
Kenneth R Conner, Sarah Lathrop, Raul Caetano, Timothy Wiegand, Kimberly Kaukeinen, Kurt B Nolte
BACKGROUND: Use of alcohol and select other drugs confer risk for injury deaths, yet how such use compares in different types of injury deaths including suicide and fatal motor vehicle collisions (MVCs) is unclear. METHODS: Individuals in New Mexico ages 18 to 54 that died in 2012 by suicide or MVC were analyzed. Toxicology results were used to code the presence of alcohol and the presence of 1 or more drugs including cocaine, opiate (oxycodone, heroin, etc.), or amphetamine or methamphetamine, yielding a 4-category variable: Alcohol + Drug, Alcohol (without drug), Drug (without alcohol), and Neither (ref)...
January 27, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28120705/investigation-of-isoindolo-2-1-a-quinoxaline-6-imines-as-topoisomerase-i-inhibitors-with-molecular-modeling-methods
#8
Balazs Balogh, Anna Carbone, Virginia Spanò, Alessandra Montalbano, Paola Barraja, Stella Cascioferro, Patrizia Diana, Barbara Parrino
BACKGROUND: Isoindolo[2,1-a]quinoxalines constitute an important class of compounds which demonstrated potent antiproliferative activity against different human tumor cell lines and topoisomerase I inhibition. In particular, their water soluble imine or iminium salts recently synthesized, showed potent growth inhibitory effect on NCI-60 tumor cell line panel and biological studies performed on the most active compounds demonstrated that they cause DNA damage via topoisomerase I poisoning...
January 23, 2017: Current Computer-aided Drug Design
https://www.readbyqxmd.com/read/28119079/deltamethrin-increases-the-fat-accumulation-in-3t3-l1-adipocytes-and-caenorhabditis-elegans
#9
Peiyi Shen, Tsung-Hsiu Hsieh, Yiren Yue, Quancai Sun, John M Clark, Yeonhwa Park
Research has shown that permethrin, a Type-I pyrethroid, increases triglyceride (fat) accumulation in adipocytes. Little is known, however, about any similar effect of deltamethrin, a Type-II pyrethroid, which produces a distinct syndrome of poisoning in mammals compared with permethrin. This study was therefore aimed to explore the role of deltamethrin on fat accumulation in 3T3-L1 adipocytes and Caenorhabditis elegans. Deltamethrin (10 μM) significantly increased the fat accumulation in 3T3-L1 adipocytes and wild type C...
January 22, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28116798/self-anticoking-of-cobalt-surface-by-subsurface-oxygen-in-fischer-tropsch-synthesis
#10
Lingshun Xu, Yuekang Jin, Zongfang Wu, Feng Xiong, Weixin Huang
Understanding the fundamental processes taking place on Co surfaces during Fischer-Tropsch (FT) synthesis is of great interest and importance. We herein report a self-anticoking mechanism of cobalt surface by subsurface oxygen. The active carbidic carbon species for FT synthesis tends to transform into the inactive graphitic carbon species on clean Co(0001) that poisons the Co surfaces. Subsurface atomic oxygen on Co(0001) can stabilize the active carbidic carbon species and quench the transformation process...
January 24, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28116229/compliance-with-washington-state-s-requirement-for-residential-carbon-monoxide-alarms
#11
Neil B Hampson, James R Holm
Carbon monoxide (CO) poisoning is responsible for significant morbidity and mortality in the US. In response, a majority of states have passed legislation in recent years requiring the installation of residential CO alarms. There is, however, no published information evaluating compliance with such laws. Employees of a Seattle medical center were surveyed in 2008 regarding home use of CO and smoke alarms. Washington State enacted legislation requiring residential CO alarms by all residences by January 1, 2013...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28107437/hyperventilation-with-maintenance-of-isocapnia-an-old-new-method-in-carbon-monoxide-intoxication
#12
Jacek Sein Anand, Daria Schetz, Wojciech Waldman, Marek Wiśniewski
INTRODUCTION: Exposure to carbon monoxide (CO) is among the most common causes of acute and chronic poisonings worldwide. The crucial point of treatment of such acute poisonings is to eliminate CO from the body as fast as possible. There are currently two approaches to the management of the CO intoxication: hyperbaric oxygen therapy (HOT) and normobaric oxygen therapy (NOT). HOT is highly effective and capable of achieving the CO elimination half-time (T½) as low as 15 minutes. Unfortunately this method is expensive and not always readily available...
2017: PloS One
https://www.readbyqxmd.com/read/28107093/adult-clonidine-overdose-prolonged-bradycardia-and-central-nervous-system-depression-but-not-severe-toxicity
#13
Geoffrey K Isbister, Simon P Heppell, Colin B Page, Nicole M Ryan
CONTEXT: There are limited reports of adult clonidine overdose. We aimed to describe the clinical effects and treatment of clonidine overdose in adults. METHODS: This was a retrospective review of a prospective cohort of poisoned patients who took clonidine overdoses (>200 μg). Demographic information, clinical effects, treatment, complications (central nervous system and cardiovascular effects) and length of stay (LOS) were extracted from a clinical database or medical records...
March 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28106219/surface-and-interface-engineering-of-fept-c-nanocatalysts-for-electro-catalytic-methanol-oxidation-enhanced-activity-and-durability
#14
Junmei Wang, Zhenlei Wang, Shuai Li, Rongming Wang, Yujun Song
A methodology by coupling a microfluidic-batch process with in situ carbon-black mixing, successive annealing and de-alloying post-treatment was developed for engineering surface and interface microstructures of FePt/C nanocomposites. Ultra-small angular FePt nanocrystals rich in vertexes/terraces/steps and with Pt contents gradually increasing from the inner to the outer part can be synthesized at certain Fe/Pt atomic ratios (2/1 or 1.1/1), which can directly grow on carbon-black for enhanced nanocrystal-carbon interface interaction by introducing the in situ carbon-black mixing process...
January 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28104739/relationship-between-prescribed-psychotropic-medications-and-co-ingested-alcohol-in-intentional-self-poisonings
#15
Kate M Chitty, Timothy Dobbins, Andrew H Dawson, Geoffrey K Isbister, Nicholas A Buckley
BACKGROUND: Acute alcohol consumption is a major risk factor for suicide, therefore investigating factors associated with alcohol-related self-harm warrant attention. AIMS: To investigate the influence of prescribed psychotropic medications on the odds of co-ingesting alcohol preceding or during intentional efforts to self-poison. METHOD: A cross-sectional analysis of consecutive hospital presentations following intentional self-poisoning was conducted...
January 19, 2017: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/28077358/biological-signaling-by-carbon-monoxide-and-carbon-monoxide-releasing-molecules-co-rms
#16
Roberto Motterlini, Roberta Foresti
Carbon monoxide (CO) is continuously produced in mammalian cells during degradation of heme. It is a stable gaseous molecule that reacts selectively with transition metals in a specific redox state and these characteristics restrict the interaction of CO with defined biological targets that transduce its signaling activity. Because of the high affinity of CO for ferrous heme, these targets can be grouped into heme-containing proteins, representing a large variety of sensors and enzymes with a series of diverse function in the cell and the organism...
January 11, 2017: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/28073439/the-competitive-dynamics-of-toxic-alexandrium-fundyense-and-non-toxic-alexandrium-tamarense-the-role-of-temperature
#17
Lisa K Eckford-Soper, Eileen Bresnan, Jean-Pierre Lacaze, David H Green, Keith Davidson
The dinoflagellate Alexandrium produces paralytic shellfish poisoning toxins. The genus is globally distributed, with Scottish waters being of particular interest due to the co-occurrence of different species and strains. In Scottish waters, Alexandrium was historically thought to be dominated by the highly toxic (Group I) Alexandrium fundyense. However, the morphologically indistinguishable (Group III) Alexandrium tamarense has recently also been found to co-occur, raising important questions in relation to Alexandrium biogeography...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28064509/acute-salicylate-poisoning-risk-factors-for-severe-outcome
#18
Rachel M Shively, Robert S Hoffman, Alex F Manini
CONTEXT: Salicylate poisoning remains a significant public health threat with more than 20,000 exposures reported annually in the United States. OBJECTIVE: We aimed to establish early predictors of severe in-hospital outcomes in Emergency Department patients presenting with acute salicylate poisoning. METHODS: This was a secondary data analysis of adult salicylate overdoses from a prospective cohort study of acute drug overdoses at two urban university teaching hospitals from 2009 to 2013...
March 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28062235/new-approach-to-biosensing-of-co-enzyme-nicotinamide-adenine-dinucleotide-nadh-by-incorporation-of-neutral-red-in-aluminum-doped-nanostructured-zno-thin-films
#19
Fidal V T, Chandra T S
Biosensing of NADH on bare electrodes has drawbacks such as high over-potential and poisoning during the oxidation reaction. To overcome this challenge a different approach has been undertaken by incorporating neutral red (NR) in Al doped ZnO (AZO) thin films using one-pot chemical bath deposition (CBD). The surface morphology of the films was hexagonal nanorods along the c-axis, perpendicular to the substrate. The thickness of the thin films were ranging from 400 to 3000nm varying dependent on time of deposition (30 to 150min)...
January 4, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28035699/lack-of-respiratory-depression-in-paracetamol-codeine-combination-overdoses
#20
Simon P E Heppell, Geoffrey K Isbister
BACKGROUND: Codeine containing analgesics are commonly taken in overdose, but the frequency of respiratory depression is unknown. We investigated whether paracetamol-codeine combination overdoses caused respiratory depression more than paracetamol alone. METHODS: We reviewed deliberate self-poisoning admissions with paracetamol (>2 g) and paracetamol-codeine combinations presenting to a tertiary toxicology unit (1987-2013). Demographic information, clinical effects, treatment (naloxone, length of stay[LOS], mechanical ventilation) were extracted from a prospective database...
December 30, 2016: British Journal of Clinical Pharmacology
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