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https://www.readbyqxmd.com/read/28161542/vasorelaxation-effect-of-glycyrrhizae-uralensis-through-the-endothelium-dependent-pathway
#1
Chu Shan Tan, Yung Sing Ch'ng, Yean Chun Loh, Mohd Zaini Asmawi, Mariam Ahmad, Mun Fei Yam
ETHNOPHARMACOLOGICAL RELEVANCE: Glycyrrhiza uralensis (G. uralensis) is one of the herbs used in traditional Chinese medicine (TCM) and serves as an envoy medicinal. Since G. uralensis plays a major role in the anti-hypertensive TCM formulae, we believe that G. uralensis might possess vasorelaxation activity. AIM OF THE STUDY: This study is designed to investigate the vasorelaxation effect of G. uralensis from various extracts and to study its pharmacology effect...
February 1, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28146411/neuroprotective-effect-of-halophyte-salicornia-herbacea-l-is-mediated-by-activation-of-heme-oxygenase-1-in-mouse-hippocampal-ht22-cells
#2
Min Sun Kim, Ji Yeon Seo, Jisun Oh, Yu Kyung Jang, Choong Hwan Lee, Jong-Sang Kim
Salicornia herbacea L. (glasswort, tungtungmadi in Korean), a halophyte that grows in salt marshes and muddy seashores along the western coast of Korea, has been used as a seasoning vegetable and a folk medicine for intestinal ailments, nephropathy, and hepatitis. As the salt-tolerant herb was reported to contain antioxidants, including tungtungmadic acid, quercetin, and chlorogenic acid, we hypothesized that the ethanolic extract of S. herbacea L. (SH extract) enriched with antioxidative compounds will have neuroprotective activity...
February 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28118132/validated-chromatographic-methods-for-the-analysis-of-two-binary-mixtures-containing-pyridoxine-hydrochloride
#3
Neven M Habib, Maha M Abdelrahman, Nada S Abdelwhab, Nourudin W Ali
Accurate and precise TLC-densitometric and HPLC-diode-array detector (DAD) methods have been developed and validated toresolve two binary mixtures containing pyridoxine hydrochloride (PYH) with either cyclizine hydrochloride (CYH) or meclizine hydrochloride (MEH). In the developed TLC-densitometric method, chromatographic separation of the three studied drugs was carried out on silica gel 60 F<sub>254</sub> plates using a developing system containing methylene chloride + acetone + methanol (7 + 1 + 0...
December 16, 2016: Journal of AOAC International
https://www.readbyqxmd.com/read/28117856/effect-of-chemical-etching-solutions-versus-air-abrasion-on-the-adhesion-of-self-adhesive-resin-cement-%C3%A2-to-ips-e-max-zircad-with-and-%C3%A2-without-aging
#4
Amal Abdelsamad Sakrana, Mutlu Özcan
OBJECTIVES: This study evaluated the adhesion of self-adhesive resin cement to zirconia after various surface conditioning methods in non-aged and aged conditions. METHODS: Zirconia (IPS e.max ZirCAD, Ivoclar Vivadent) and resin composite blocks were obtained and randomly divided into four groups according to one of the following surface conditioning methods: C: No surface treatment (Control); AS: Air abrasion (50 µm Al2O3) at low pressure (0.2 MPa) plus silane (Monobond Plus, Ivoclar Vivadent); MC: Methylene chloride for 60 min; CE: Chemical etching solution at 100°C for 60 min...
2017: International Journal of Esthetic Dentistry
https://www.readbyqxmd.com/read/28099873/antimicrobial-photodynamic-therapy-as-an-adjunct-for-treatment-of-deep-carious-lesions-a-systematic-review
#5
REVIEW
Fabian Cieplik, Wolfgang Buchalla, Elmar Hellwig, Ali Al-Ahmad, Karl-Anton Hiller, Tim Maisch, Lamprini Karygianni
For deep carious lesions, a more conservative treatment modality ("selective caries removal") has been proposed, where only the heavily contaminated dentine is removed. In this regard, effective adjuncts for cavity disinfection such as the antimicrobial photodynamic therapy (aPDT) can be valuable clinically prior to definitive restoration. Therefore, the aim of this study was to systematically assess clinical studies on the effectiveness of aPDT as a supplementary tool in the treatment of deep caries lesions...
January 15, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28078263/cytotoxic-effects-of-strawberry-korean-raspberry-and-mulberry-extracts-on-human-ovarian-cancer-a2780-cells
#6
Dahae Lee, Ki Sung Kang, Sanghyun Lee, Eun Ju Cho, Hyun Young Kim
Reactive oxygen species are tumorigenic by their ability to increase cell proliferation, survival, and cellular migration. The purpose of the present study was to compare the antioxidant activity and cytotoxic effects of 3 berry extracts (strawberry, Korean raspberry, and mulberry) in A2780 human ovarian carcinoma cells. Except for raspberry, the ethyl acetate or methylene chloride fractions of berries containing phenolic compounds exerted dose dependent free radical scavenging activities. In the raspberry fractions, the hexane fraction also exhibited potent antioxidant activity...
December 2016: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28069619/occupational-exposure-to-solvents-and-risk-of-head-and-neck-cancer-in-women-a-population-based-case-control-study-in-france
#7
Matthieu Carton, Christine Barul, Gwenn Menvielle, Diane Cyr, Marie Sanchez, Corinne Pilorget, Brigitte Trétarre, Isabelle Stücker, Danièle Luce
OBJECTIVE: Our objective was to investigate the association between head and neck cancer and occupational exposure to chlorinated, oxygenated and petroleum solvents in women. METHODS: Investigation of occupational and environmental CAuses of REspiratory cancers (ICARE), a French population-based case-control study, included 296 squamous cell carcinomas of the head and neck (HNSCC) in women and 775 female controls. Lifelong occupational history was collected. Job-exposure matrices allowed to assess exposure to 5 chlorinated solvents (carbon tetrachloride; chloroform; methylene chloride; perchloroethylene; trichloroethylene), 5 petroleum solvents (benzene; special petroleum product; gasoline; white spirits and other light aromatic mixtures; diesel, fuels and kerosene) and 5 oxygenated solvents (alcohols; ketones and esters; ethylene glycol; diethyl ether; tetrahydrofuran)...
January 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28067653/photocatalytic-degradation-of-methyl-orange-methylene-blue-and-rhodamine-b-with-agcl-nanocatalyst-synthesised-from-its-bulk-material-in-the-ionic-liquid-p6-6-6-14-cl
#8
Borja Rodríguez-Cabo, Iago Rodríguez-Palmeiro, Raquel Corchero, Rosario Rodil, Eva Rodil, Alberto Arce, Ana Soto
The photocatalytic degradation of wastewater containing three industrial dyes belonging to different families, methyl orange (MO), methylene blue (MB) and Rhodamine B (RhB), was studied under UV-Vis irradiation using synthesised silver chloride nanoparticles. The nanocatalyst was prepared by a dissolution/reprecipitation method starting from the bulk powder and the ionic liquid trihexyl(tetradecyl)phosphonium chloride, [P6 6 6 14]Cl, without addition of other solvents. The obtained catalyst was characterised by UV-Vis absorbance, X-ray powder diffraction, transmission electron microscopy and scanning electron microscopy...
January 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28035101/polymeric-structure-of-a-coproporphyrin-i-ruthenium-ii-complex-a-powder-diffraction-study
#9
Sergey V Andreev, Sergey A Zverev, Ilya A Zamilatskov, Nadezhda M Kurochkina, Gelii V Ponomarev, Andrew N Fitch, Vladimir V Chernyshev
Porphyrin complexes of ruthenium are widely used as models for the heme protein system, for modelling naturally occurring iron-porphyrin systems and as catalysts in epoxidation reactions. The structural diversity of ruthenium complexes offers an opportunity to use them in the design of multifunctional supramolecular assemblies. Coproporphyrins and metallocoproporphyrins are used as sensors in bioassay and the potential use of derivatives as multiparametric sensors for oxygen and H(+) is one of the main factors driving a growing interest in the synthesis of new porphyrin derivatives...
January 1, 2017: Acta Crystallographica. Section C, Structural Chemistry
https://www.readbyqxmd.com/read/28032246/identification-and-characterization-of-diploid-and-tetraploid-in-platycodon-grandiflorum
#10
Jeoung-Hwa Shin, Yun Gyong Ahn, Ju-Hee Jung, Sun-Hee Woo, Hag-Hyun Kim, Shela Gorinstein, Hee-Ock Boo
Platycodon grandiflorum (PG), a species of herbaceous flowering perennial plant of the family Campanulaceae, has been used as a traditional oriental medicine for bronchitis, asthma, pulmonary tuberculosis, diabetes, hepatic fibrosis, bone disorders and many others similar diseases and as a food supplement. For the primary profiling of PG gas chromatography coupled with high resolution - time of flight mass spectrometry (GC/HR-TOF MS) was used as an analytical tool. A comparison of optimal extraction of metabolites was carried out with a number of solvents [hexane, methylene chloride, methanol, ethanol, methanol: ethanol (70:30, v:v)]...
December 28, 2016: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/27992175/label-free-electrochemical-biosensor-for-monitoring-of-chloride-ion-in-an-animal-model-of-alzhemier-s-disease
#11
Hui Dong, Limin Zhang, Wei Liu, Yang Tian
The potential damage of Alzheimer's disease (AD) in brain function has attracted extensive attention. As the most common anion, Cl(-) has been indicated to play significant roles in brain diseases, particularly in the pathological process of AD. In this work, a label-free selective and accurate electrochemical biosensor was first developed for real-time monitoring of Cl(-) levels in a mouse brain model of AD and rat brain upon global cerebral ischemia. Silver nanoparticles (AgNPs) were designed and synthesized as selective recognition element for Cl(-), while 5'-MB-GGCGCGATTTT-SH-3' (SH-DNA-MB, MB = methylene blue) was selected as an inner reference molecule for a built-in correction to avoid the effects from the complicated brain...
December 19, 2016: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/27987694/preparation-of-crosslinked-poly-acryloyloxyethyltrimethyl-ammonium-chloride-microsphere-and-its-adsorption-and-mechanism-towards-shikimic-acid
#12
Jiying Men, Ruixin Wang, Huan Li, Xinyan Li, Shanshan Yang, Haisi Liu, Baojiao Gao
Shikimic acid (SA) is a key raw material for the synthesis of the antiviral drug, but its extraction and separation from plants is still limited. Crosslinked poly (acryloyloxyethyltrimethyl ammonium chloride, DAC) microspheres were synthesized via inverse-phase suspension polymerization. In the synthesizing, N,N'-methylene bisacrylamide (MBA) was used as crosslinker, cyclohexane as dispersed medium and span-60 as dispersants, obtaining CPDAC gel microspheres. The effect of polymerization condition on balling performance and the characteristics of CPDAC were examined...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27846410/a-structural-and-temporal-study-of-the-surfactants-behenyltrimethylammonium-methosulfate-and-behenyltrimethylammonium-chloride-adsorbed-at-air-water-and-air-glass-interfaces-using-sum-frequency-generation-spectroscopy
#13
Sami A Goussous, Mike T L Casford, Simon A Johnson, Paul B Davies
Molecular scale information about the structure of surfactants at interfaces underlies their application in consumer products. In this study the non-linear optical technique of Sum Frequency Generation (SFG) vibrational spectroscopy has been used to investigate the structure and temporal behaviour of two cationic surfactants used frequently in hair conditioners. SFG spectra of films of behenyltrimethylammonium methosulfate (BTMS) and behenyltrimethylammonium chloride (BTAC) were recorded at the air/water interface and on glass slides following Langmuir Blodgett (LB) deposition...
February 15, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/27833174/thienyl-difluoroboron-%C3%AE-diketonates-in-solution-and-polylactide-media
#14
Milena Kolpaczynska, Christopher A DeRosa, William A Morris, Cassandra L Fraser
Difluoroboron β-diketonates have impressive optical properties in both solution and the solid state. In particular, both fluorescence and room-temperature phosphorescence are present when the dyes are confined to a rigid matrix, such as poly(lactic acid) (PLA). To expand current knowledge and color range capabilities of this unique type of multi-emitting chromophore, a series of thienyl-substituted BF2bdk complexes have been synthesized. The photophysical properties were investigated in methylene chloride solution and in the solid state as dye/PLA blends...
2016: Australian Journal of Chemistry
https://www.readbyqxmd.com/read/27817926/voc-characteristics-and-inhalation-health-risks-in-newly-renovated-residences-in-shanghai-china
#15
Haixia Dai, Shengao Jing, Hongli Wang, Yingge Ma, Li Li, Weimin Song, Haidong Kan
BACKGROUND: Exposure to indoor VOCs is expected to link to a variety of negative health outcome. The popularity of decorations and refurbishment in homes in China has given rise to indoor elevated VOC levels, potentially posing health threats to residents. METHODS: In this study, concentrations of 101 VOC compounds and associated health risks were investigated in newly renovated homes in Shanghai. The potential excess inhalation health risks from home exposure of 17 health-related VOCs were estimated by the Inhalation Unit Risk (IUR) and Reference Concentration (RfC) proposed by US EPA...
January 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27808520/organocatalytic-synthesis-of-methylene-bridged-n-heterobiaryls
#16
David E Stephens, Vu T Nguyen, Bhuwan Chhetri, Emily R Clark, Hadi D Arman, Oleg V Larionov
A one-step synthesis of 1,1'- and 2,2'-methylene-bridged N-heterobiaryls directly from the corresponding N-heterocycles in a reaction with methylmagnesium chloride in the presence of catalytic amounts of N,N,N',N'-tetramethylethylenediamine under thermal and microwave conditions is reported. The split-and-merge methylenation of 2,2'-N-heterobiaryls and the direct ortho-alkylation of quinoline and isoquinoline with Grignard reagents have also been developed. Mechanistic studies identified several intermediates and provided insight into the formation and roles of magnesium hydride species in the process...
November 18, 2016: Organic Letters
https://www.readbyqxmd.com/read/27803178/occupational-exposure-to-chlorinated-solvents-and-kidney-cancer-a-case-control-study
#17
Mark P Purdue, Patricia A Stewart, Melissa C Friesen, Joanne S Colt, Sarah J Locke, Misty J Hein, Martha A Waters, Barry I Graubard, Faith Davis, Julie Ruterbusch, Kendra Schwartz, Wong-Ho Chow, Nathaniel Rothman, Jonathan N Hofmann
OBJECTIVES: Trichloroethylene, a chlorinated solvent widely used for metal degreasing, is classified by the International Agency for Research on Cancer as a kidney carcinogen. Other chlorinated solvents are suspected carcinogens, most notably the cleaning solvent perchloroethylene, although it is unclear whether they are associated with kidney cancer. We investigated kidney cancer associations with occupational exposure to 6 chlorinated solvents (trichloroethylene, perchloroethylene, 1,1,1-trichloroethane, carbon tetrachloride, chloroform, and methylene chloride) within a case-control study using detailed exposure assessment methods...
November 1, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27785939/vasorelaxant-action-of-the-chloroform-fraction-of-orthosiphon-stamineus-via-no-cgmp-pathway-potassium-and-calcium-channels
#18
Mun Fei Yam, Chu Shan Tan, Mariam Ahmad, Shibao Ruan
Orthosiphon stamineus Benth. (Lamiaceae) is an important plant in traditional folk medicine that is used to treat hypertension and kidney stones. In humans, this plant has been tested as an addition regiment for antihypertensive treatment. Among the treatments for hypertension, O. stamineus had been to have diuretic and vasorelaxant effects in animal models. There is still very little information regarding the vasorelaxant effect of O. stamineus. Therefore, the present study was designed to investigate the vasorelaxant activity and mechanism of action of the fractions of O...
2016: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/27785112/in-vitro-vasodilatory-activity-and-possible-mechanisms-of-the-crude-extracts-and-fractions-of-moringa-stenopetala-baker-f-cufod-leaves-in-isolated-thoracic-aorta-of-guinea-pigs
#19
Bekesho Geleta, Eyasu Makonnen, Asfaw Debella, Abiy Abebe, Netsanet Fekadu
Moringa stenopetala, a plant belonging to the family of Moringaceae, is traditionally used for the treatment of hypertension and diabetes in Ethiopia. This study evaluates the in vitro vasodilatory effect of the extract of M. stenopetala leaves and the possible mechanisms in precontracted isolated thoracic aorta of guinea pigs. A guinea pig was sacrificed by gentle cervical dislocation, and the thoracic aortic ring was removed, cut spirally, and mounted in an organ bath containing Krebs-Henseleit physiological solution maintained at 37°C, and then the solution was aerated with carbogen (95% O2 and 5% CO2)...
2016: Journal of Experimental Pharmacology
https://www.readbyqxmd.com/read/27779894/influence-of-sulforaphane-metabolites-on-activities-of-human-drug-metabolizing-cytochrome-p450-and-determination-of-sulforaphane-in-human-liver-cells
#20
Alena Vanduchova, Veronika Tomankova, Pavel Anzenbacher, Eva Anzenbacherova
The influence of metabolites of sulforaphane, natural compounds present in broccoli (Brassica oleracea var. botrytis italica) and in other cruciferous vegetables, on drug-metabolizing cytochrome P450 (CYP) enzymes in human liver microsomes and possible entry of sulforaphane into human hepatic cells were investigated. Metabolites studied are compounds derived from sulforaphane by the mercapturic acid pathway (conjugation with glutathione and by following reactions), namely sulforaphane glutathione and sulforaphane cysteine conjugates and sulforaphane-N-acetylcysteine...
December 2016: Journal of Medicinal Food
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