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https://www.readbyqxmd.com/read/27921413/short-time-efficiency-of-rhinophototherapy-in-management-of-patients-with-allergic-rhinitis-resistant-to-medical-therapy
#1
Soheila Alyasin, Seyed Hesamedin Nabavizadeh, Hamidreza Houshmand, Hossein Esmaeilzadeh, Sina Jelodar, Reza Amin
Allergic rhinitis is one of the most common health problems with a major effect on the quality of life. We intended to treat Allergic Rhinitis (AR) in patients who are either unresponsive to antihistamines or their job requires optimal alertness that may be disturbed by antihistamine's side effects and those who do not comply with the regular use. We tried short term phototherapy and evaluated its effect on AR. As phototherapy is effective in the treatment of atopic dermatitis (AD) and the same allergens can produce both AD and AR, phototherapy is proposed as a new tool in the AR treatment...
August 2016: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/27919663/efficacy-of-low-level-laser-therapy-in-the-treatment-of-burning-mouth-syndrome-a-systematic-review
#2
REVIEW
Sadeq Ali Al-Maweri, Fawad Javed, Butchibabu Kalakonda, Nader A AlAizari, Walid Al-Soneidar, Ameen Al-Akwa
BACKGROUND: Burning mouth syndrome (BMS) is a chronic pain condition with indefinite cure, predominantly affecting post-menopausal women. The aim of this study was to systematically review the efficacy of low level laser therapy in the treatment of burning mouth syndrome (BMS). METHODS: PubMed, Embase and Scopus were searched from date of inception till and including October 2016 using various combinations of the following keywords: burning mouth syndrome, BMS, stomatodynia, laser therapy, laser treatment and phototherapy...
December 2, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27918115/an-amphiphilic-ruthenium-polymetallodrug-for-combined-photodynamic-therapy-and-photochemotherapy-in-vivo
#3
Wen Sun, Shuyi Li, Bernhard Häupler, Juan Liu, Shubin Jin, Werner Steffen, Ulrich S Schubert, Hans-Jürgen Butt, Xing-Jie Liang, Si Wu
An amphiphilic Ru-containing block copolymer is used as a photoactivated polymetallodrug for anticancer phototherapy. The block copolymer self-assembles into nanoparticles, which can accumulate at tumor sites in a mouse model. Red light irradiation of the block copolymer nanoparticles releases anticancer Ru complexes and generates cytotoxic (1) O2 , both of which can inhibit tumor growth.
December 5, 2016: Advanced Materials
https://www.readbyqxmd.com/read/27905011/under-treatment-of-patients-with-moderate-to-severe-psoriasis-in-the-united-states-analysis-of-medication-usage-with-health-plan-data
#4
April W Armstrong, J Will Koning, Simon Rowse, Huaming Tan, Carla Mamolo, Mandeep Kaur
INTRODUCTION: Psoriasis is a chronic inflammatory disorder with significant morbidity and mortality, but a persistent gap appears to exist for the adequate treatment of patients with moderate to severe disease. As the extent of under-treatment is unknown, we attempted to determine overall treatment patterns and estimate under-treatment using a large database. METHODS: Data from the US National Health and Wellness Survey was used to estimate the proportion of patients with mild, moderate or severe psoriasis...
November 30, 2016: Dermatology and Therapy
https://www.readbyqxmd.com/read/27900946/childhood-psoriasis
#5
Emmanuel Mahé
Psoriasis is a common chronic inflammatory skin disease. Recently, few data have been published on epidemiology, comorbidity, or therapy in children with psoriasis. Psoriasis affects up to 2% of children in Europe, even during the first months of life. The link between psoriasis and metabolic comorbidities has been highlighted, notably in relation to excessive weight and obesity. The clinical picture of psoriasis in childhood resembles adult disease, however, some clinical features are noteworthy: neonatal diaper rash is relatively specific, face involvement and guttate psoriasis are more common, plaques are often smaller, and scales are finer and softer than in adults...
November 29, 2016: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/27899949/corrigendum-to-effect-of-narrow-band-ultraviolet-b-phototherapy-and-methotrexate-on-microrna-146a-levels-in-blood-of-psoriatic-patients
#6
Amal Abou El-Fadle, Asmaa M Ele-Refaei, Fatma M El-Esawy
[This corrects the article DOI: 10.1155/2015/145769.].
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27892584/a-short-history-of-phototherapy-vitamin-d-and-skin-disease
#7
Paul Jarrett, Robert Scragg
The earliest record between sun exposure and skin disease goes back five millennia to the ancient Egyptians. The modern scientific era of medical light therapy and skin diseases started in 1877 when Downs and Blunt reported that exposure to light inhibited fungal growth in test tubes. Continuing research generated a growing medical interest in the potential the effects of light to treat and cure skin diseases considered as parasitic. This culminated in the awarding of the 1903 Nobel Prize in Medicine to Niels Finsen for his pioneering work showing that light could successfully treat cutaneous mycobacterium tuberculosis (lupus vulgaris), a disfiguring disorder common at the time...
November 28, 2016: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/27890732/programmed-near-infrared-light-responsive-drug-delivery-system-for-combined-magnetic-tumor-targeting-magnetic-resonance-imaging-and-chemo-phototherapy
#8
Qianhua Feng, Yuanyuan Zhang, Wanxia Zhang, Yongwei Hao, Yongchao Wang, Hongling Zhang, Lin Hou, Zhenzhong Zhang
: In this study, an intelligent drug delivery system was developed by capping doxorubicin (DOX)-loaded hollow mesoporous CuS nanoparticles (HMCuS NPs) with superparamagnetic iron oxide nanoparticles (IONPs). Under near infrared (NIR) light irradiation, the versatile HMCuS NPs could exploit the merits of both photothermal therapy (PTT) and photodynamic therapy (PDT) simultaneously. Herein, the multifunctional IONPs as gatekeeper with the enhanced capping efficiency were supposed to realize "zero premature release" and minimize the adverse side effects during the drug delivery in vivo...
November 24, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27890454/effect-of-phototherapy-on-b-and-t-lymphocytes-in-egyptian-infants-suffering-from-neonatal-jaundice
#9
I K Eyada, A L El Saie, G A Ibrahem, N M Riad
BACKGROUND: Neonatal jaundice is one of the most common problems that affect newborn infants, and phototherapy is usually used for treatment. OBJECTIVES: Evaluation of the effect of phototherapy on neonatal immune system through measuring the percentage of B and T lymphocytes and determining the frequency of development of infections and need for hospitalisation during the first six months of life. METHODS: A prospective cohort study was conducted on 50 full term new-borns; 25 with indirect hyperbilirubinaemia and treated with conventional phototherapy and 25 healthy matched neonates as untreated controls...
November 24, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27886903/allergic-contact-dermatitis
#10
REVIEW
Lisa Kostner, Florian Anzengruber, Caroline Guillod, Mike Recher, Peter Schmid-Grendelmeier, Alexander A Navarini
Allergic contact dermatitis (ACD) is a common skin disease caused by a T cell-mediated immune reaction to usually innocuous allergens. ACD can have grave medical and socioeconomic consequences. ACD and irritant contact dermatitis often occur together. A detailed history and clinical examination are crucial and guide patch testing, which is the gold standard to diagnose ACD. T-cell clones persisting in the skin may explain the tendency of ACD to relapse even after years of allergen avoidance. Traditional treatments for ACD are topical steroids, calcineurin inhibitors, phototherapy, retinoids (including the recent alitretinoin), and immunosuppressants...
February 2017: Immunology and Allergy Clinics of North America
https://www.readbyqxmd.com/read/27885521/laser-and-led-phototherapy-on-midpalatal-suture-after-rapid-maxilla-expansion-raman-and-histological-analysis
#11
Cristiane Becher Rosa, Fernando Antonio Lima Habib, Telma Martins de Araújo, Jean Nunes Dos Santos, Maria Cristina T Cangussu, Artur Felipe Santos Barbosa, Isabele Cardoso Vieira de Castro, Antônio Luiz Barbosa Pinheiro
The aim of this study was to analyze the effect of laser or LED phototherapy on the acceleration of bone formation at the midpalatal suture after rapid maxilla expansion. Forty-five rats were divided into groups at 7 days (control, expansion, expansion and laser irradiation, and expansion and LED irradiation) and into 14 days (expansion, expansion and laser in the 1st week, expansion and LED in the 1st week, expansion and laser in the 1st and 2nd weeks, expansion and LED in the 1st and 2nd weeks). Laser/LED irradiation occurred every 48 h...
November 24, 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27885324/clinical-outcome-of-a-novel-anti-cd6-biologic-itolizumab-in-patients-of-psoriasis-with-comorbid-conditions
#12
Vinay Singh
Psoriasis is a common, chronic, immune mediated, inflammatory disease of skin characterized by red patches enclosed with white scales and affects 2-3% of people in the world. Topical therapy, phototherapy, and systemic therapy were employed for management of disease from many last decades. However, long term uses of these agents are associated with unwanted effects and toxicities. Recently, Itolizumab has been developed as world's first anti-CD6 humanized monoclonal IgG1 antibody for the management of moderate-to-severe chronic plaque psoriasis in India...
2016: Dermatology Research and Practice
https://www.readbyqxmd.com/read/27884637/phototheranostic-nanoplatform-based-on-a-single-cyanine-dye-for-image-guided-combinatorial-phototherapy
#13
Tony Duong, Xiaoning Li, Bona Yang, Canan Schumann, Hassan A Albarqi, Olena Taratula, Oleh Taratula
This study represents a novel phototheranostic nanoplatform based on the near-infrared (NIR) heptamethine cyanine dye, IR775, which is capable of concurrent real-time fluorescence imaging and cancer eradication with combinatorial phototherapy. To achieve water solubility and enhance tumor delivery, the hydrophobic IR775 dye was loaded into a biocompatible polymeric nanoparticle with a diameter of ~40nm and slightly negative surface charge (-2.34mV). The nanoparticle-encapsulated hydrophobic IR775 dye (IR775-NP) is characterized by an enhanced fluorescence quantum yield (16%) when compared to the water soluble analogs such as ICG (2...
November 21, 2016: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/27883996/phototherapy-with-narrow-band-uvb-in-adult-guttate-psoriasis-results-and-patient-assessment
#14
Montserrat Fernández-Guarino, Sonsoles Aboín-González, Diana Velázquez, Lucia Barchino, Natividad Cano, Pablo Lázaro
BACKGROUND: Acute guttate psoriasis (AGP) is a distinctive clinical entity with good response to treatment with narrow-band ultraviolet B (NB-UVB). OBJECTIVE: To investigate the results of NB-UVB phototherapy in adult patients with adult guttate psoriasis. MATERIAL AND METHODS: We carried out a prospective, open, and observational study. Patients over 18 years with more than 5% of body surface area affected were included. The PASI was assessed prior to and after treatment...
November 25, 2016: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/27877241/photo-decomposable-organic-nanoparticles-for-combined-tumor-optical-imaging-and-multiple-phototherapies
#15
Wenjun Miao, Hyungjun Kim, Vipul Gujrati, Jin Yong Kim, Hyeongsu Jon, Yonghyun Lee, Minsuk Choi, Jinjoo Kim, Soyoung Lee, Dong Yun Lee, Sukmo Kang, Sangyong Jon
Combination of photodynamic therapy (PDT) with photothermal therapy (PTT) has achieved significantly improved therapeutic efficacy compared to a single phototherapy modality. However, most nanomaterials used for combined PDT/PTT are made of non-biodegradable materials (e.g., gold nanorods, carbon nanotubes, and graphenes) and may remain intact in the body for long time, raising concerns over their potential long-term toxicity. Here we report a new combined PDT/PTT nanomedicine, designated SP(3)NPs, that exhibit photo-decomposable, photodynamic and photothermal properties...
2016: Theranostics
https://www.readbyqxmd.com/read/27877062/systemic-abnormalities-of-psoriatic-patients-a-retrospective-study
#16
Li Yin, Jia-Li Xu, Ying-Ying Hu, Andrew Johnston, Zhi-Qiang Yin
BACKGROUND: Psoriasis is a chronic immune-mediated inflammatory disease related to the metabolic syndrome, cardiovascular disease, and other comorbidities. However, so far there has been no specific research concerning systemic abnormalities in psoriatic patients. OBJECTIVE: A retrospective study was conducted focusing on the detailed systemic abnormalities in psoriatic patients. METHODS: Psoriatic inpatients data was collected from July 2009 to September 2015...
2016: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/27876738/-treatment-with-the-use-of-microcurrent-lymphatic-drainage-physiotherapy-during-the-postoperative-period-following-rhinoplastic-surgery
#17
T A Aleksanyan, E V Kazantsev
The objective of the present study was to evaluate the effectiveness of the combined treatment of the patients who had undergone either primary or secondary rhinoplastic surgery with the use of photo- and magnetic therapy in comparison with the effectiveness of phototherapy in the combination with microcurrent therapy. The patients were divided into four groups depending on the type of the surgical intervention and the mode of the combined physiotherapeutic treatment. All the patients were given combined physiotherapeutic treatment in addition to the standard pharmacotherapy starting from the second day of the postoperative period...
2016: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/27876302/the-risk-of-melanoma-and-hematologic-cancers-in-patients-with-psoriasis
#18
Shivani P Reddy, Kathryn Martires, Jashin J Wu
BACKGROUND: The risk of melanoma and hematologic cancers in patients with psoriasis is controversial. OBJECTIVE: We sought to assess the risk of melanoma and hematologic cancers in patients with psoriasis, and the association with different treatments. METHODS: We used case-control and retrospective cohort designs to determine melanoma or hematologic cancer risk in patients with psoriasis. Risk with treatment type was assessed using Fisher exact test...
November 19, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27869251/an-increased-genotoxic-risk-in-lymphocytes-from-phototherapy-treated-hyperbilirubinemic-neonates
#19
Seyed Alireza Mesbah-Namin, Maryam Shahidi, Maryam Nakhshab
BACKGROUND: Phototherapy is believed to be a safe method for the management of hyperbilirubinemia. However, there are some controversial issues regarding the genotoxic effects of phototherapy on DNA. The aim of this study was to investigate morphologically both phototherapy-induced DNA double-strand breaks (DSBs) and apoptosis in lymphocytes derived from jaundiced and non-jaundiced neonates. METHODS: Newborns were divided into three groups, including phototherapy-treated (PT, n=30) jaundiced newborns with total serum bilirubin (TSB) levels >15 mg/dl, non-treated jaundiced newborns (C+, n=27), as positive, as well as healthy negative (C-, n=30) controls with TSB levels ranging from 10 and 15 mg/dl and less than 5 mg/dl, respectively...
November 21, 2016: Iranian Biomedical Journal
https://www.readbyqxmd.com/read/27868221/what-s-new-in-atopic-eczema-an-analysis-of-systematic-reviews-published-in-2014-part-2-treatment-and-prevention
#20
REVIEW
A Lloyd-Lavery, N K Rogers, S J Hatfield, D Grindlay, R Barnett, K S Thomas
This review forms part of a series of annual updates that summarize the evidence base for atopic eczema (AE). It provides a summary of key findings from 12 systematic reviews (SRs) that were published or indexed during 2014, and focuses on the treatment and prevention of AE. For an update of SRs on the epidemiology, mechanisms of disease and methodological issues, see Part 1 of this update. Although phototherapy and various systemic medications (including ciclosporin, azathioprine and methotrexate) are commonly used to treat AE, many of these have not been robustly assessed in head-to-head randomized controlled trials...
November 21, 2016: Clinical and Experimental Dermatology
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