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appearance is a function of face

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https://www.readbyqxmd.com/read/28216810/nasal-correction-in-nasomaxillary-hypoplasia-binder-s-syndrome-an-optimised-classification-and-treatment
#1
Venkata Ramana Yamani, Shakuntala Ghosh, Shreekumar Tirunagari
BACKGROUND: Nasomaxillary hypoplasia is a rare congenital disorder involving the central face. It imparts a distinctive appearance to the individual face as the age advances. Severity of the disorder varies, so do the manifestations. METHODS: This was a retrospective study conducted on the records and photographic data of 560 rhinoplasty cases performed between 2006 March and 2016 March. About 16 cases of nasomaxillary hypoplasia were selected from the group and they were classified based on the severity of the features...
September 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28209907/equivalent-dose-rate-at-1m-of-patients-with-known-or-suspected-neuroendocrine-tumor-exiting-a-nuclear-medicine-department-after-68-ga-dotatoc-18-f-fdopa-or-18-f-fdg-pet-ct-or-111-in-pentetreotide-or-123-i-mibg-spect-ct
#2
Jules Zhang-Yin, Anne-Sophie Dirand, Myriam Sasanelli, Gwenaelle Corrégé, Aude Peudon, Thierry Kiffel, Valérie Nataf, Jérôme Clerc, Françoise Montravers, Jean-Noël Talbot
(123)I-mIBG and (111)In-pentetrotide SPECT have been used for functional imaging of neuroendocrine tumors (NET) for the last two decades. More recently, PET/CT imaging with (18)F-FDG, (18)F-FDOPA and (68)Ga somatostatin-receptor ligands in NETs has been expanding. No direct measurements of the dose rate from NET patients exiting the nuclear medicine department could be found in the literature after PET/CT with (18)F-FDOPA or (68)Ga-DOTATOC, a somatostatin analogue. Methods: We measured the dose rates from NET patients undergoing PET/CT or SPECT/CT in our centers...
February 16, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28202765/the-lateral-organization-of-influenza-virus-proteins-in-the-budozone-region-of-the-plasma-membrane
#3
George P Leser, Robert A Lamb
Influenza virus assembles and buds at the plasma membrane of virus-infected cells. The viral proteins assemble at the same site on the plasma membrane for budding to occur. This involves a complex web of interactions among viral proteins. Some, like HA, NA, and M2 are integral membrane proteins. M1 is peripherally membrane associated, whereas NP associates with the viral RNA to form an RNP complex that associates with the cytoplasmic face of the plasma membrane. Furthermore, HA and NP have been shown to be concentrated in cholesterol-rich membrane raft domains whereas M2, although containing a cholesterol binding motif, is not raft associated...
February 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28194640/life-beyond-a-diagnosis-of-glioblastoma-a-systematic-review-of-the-literature
#4
REVIEW
L Gately, S A McLachlan, A Dowling, J Philip
BACKGROUND: The median survival of glioblastoma is 12-14 months with less than 10% of patients surviving at least 2 years from diagnosis. Patients diagnosed with glioblastoma face poor prognosis, significant symptom burden, and high care needs. The aim of this study is to undertake a literature review to document the issues encountered by long-term survivors of glioblastoma, a small but important subset of patients. METHODS: MEDLINE, PsychInfo, and EMBASE were searched with core concepts: (1) glioblastoma, (2) survivor, and (3) terms pertaining to survivorship issues...
February 13, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28165728/hepatoprotective-effect-of-%C3%AF-glutathione-in-a-murine-model-of-acetaminophen-induced-liver-toxicity
#5
Swati S More, Jaime Nugent, Ashish P Vartak, Steffan M Nye, Robert Vince
Ψ-Glutathione (ψ-GSH) is an orally bioavailable and metabolism-resistant glutathione analogue that has been shown previously to substitute glutathione in most of its biochemical roles. Described here in its entirety is the preclinical evaluation of ψ-GSH as a rescue agent for acetaminophen (APAP) overdose: an event where time is of essence. By employing a murine model, four scenarios commonly encountered in emergency medicine are reconstructed. ψ-GSH is juxtaposed against N-acetylcysteine (NAC), the sole clinically available drug, in each of the scenarios...
February 16, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28138426/alterations-in-visual-cortical-activation-and-connectivity-with-prefrontal-cortex-during-working-memory-updating-in-major-depressive-disorder
#6
Thang M Le, John A Borghi, Autumn J Kujawa, Daniel N Klein, Hoi-Chung Leung
The present study examined the impacts of major depressive disorder (MDD) on visual and prefrontal cortical activity as well as their connectivity during visual working memory updating and related them to the core clinical features of the disorder. Impairment in working memory updating is typically associated with the retention of irrelevant negative information which can lead to persistent depressive mood and abnormal affect. However, performance deficits have been observed in MDD on tasks involving little or no demand on emotion processing, suggesting dysfunctions may also occur at the more basic level of information processing...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28138125/face-transplant-in-an-advanced-neurofibromatosis-type-1-patient
#7
Łukasz Krakowczyk, Adam Maciejewski, Cezary Szymczyk, Krzysztof Oleś, Stanisław Półtorak
BACKGROUND The human face is a one-of-a-kind structure with unique morphology, complexity, and function, in which different subunits are not even similar to other parts of the body. Therefore, extended complex deficits of the face are usually difficult to reconstruct, and autologous tissue restoration is generally not able to give a satisfactory aesthetic and functional outcome. The main goal of face allotransplantation is to restore symmetry, contour, and appearance as well as function of the face, especially control of orbicularis oculi and oris muscle physiology...
January 31, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28128377/recent-developments-in-reversible-photoregulation-of-oligonucleotide-structure-and-function
#8
REVIEW
Anouk S Lubbe, Wiktor Szymanski, Ben L Feringa
There is a growing interest in the photoregulation of biological functions, due to the high level of spatiotemporal precision achievable with light. Additionally, light is non-invasive and waste-free. In particular, the photoregulation of oligonucleotide structure and function is a rapidly developing study field with relevance to biological, physical and material sciences. Molecular photoswitches have been incorporated in oligonucleotides for 20 years, and the field has currently grown beyond fundamental studies on photochemistry of the switches and DNA duplex stability, and is moving towards applications in chemical biology, nanotechnology and material science...
February 20, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28116580/disrupted-face-processing-in-frontotemporal-dementia-a-review-of-the-clinical-and-neuroanatomical-evidence
#9
REVIEW
Rosalind Hutchings, Romina Palermo, Olivier Piguet, Fiona Kumfor
Faces play an integral role in day-to-day functioning, particularly for social interactions where dynamic and rapid processing of information is vital. Analysis of faces allows an individual to ascertain a wide range of information including deciphering mood and identity, with these assessments directing an individual's subsequent response and behaviours. The prominent social and emotional deficits observed in frontotemporal dementia (FTD), a younger-onset dementia syndrome, may in part reflect a breakdown of the face processing network...
January 23, 2017: Neuropsychology Review
https://www.readbyqxmd.com/read/28106069/identification-of-novel-cellular-clusters-define-a-specialized-area-in-the-cerebellar-periventricular-zone
#10
María Alejandra González-González, Gabriela B Gómez-González, Marymar Becerra-González, Ataúlfo Martínez-Torres
The periventricular zone of cerebellum is a germinative niche during the embryonic development, nevertheless its structural organization and functional implications in adult have not been widely studied. Here we disclose the presence of two novel clusters of cells in that area. The first one was named the subventricular cellular cluster (SVCC) and is composed of cells that express glial and neuronal markers. The second was named the ventromedial cord (VMC) and appears as a streak of biciliated cells with microvillosities facing the ventricle, that includes GFAP(+) and nestin(+) cells organized along the periventricular vasculature...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28101879/private-sector-involvement-in-times-of-armed-conflict-what-are-the-constraints-for-trading-medical-equipment
#11
Georg Schmidt
OBJECTIVE: Today, healthcare facilities are highly dependent on the private sector to keep their medical equipment functioning. Moreover, private sector involvement becomes particularly important for the supply of spare parts and consumables. However, in times of armed conflict, the capacity of the corporate world appears to be seriously hindered. Subsequently, this study researches the influence of armed conflict on the private medical equipment sector. DESIGN: This study follows a qualitative approach by conducting 19 interviews with representatives of the corporate world in an active conflict zone...
November 2016: Journal of Emergency Management: JEM
https://www.readbyqxmd.com/read/28095652/exosomal-trafficking-in-xenopus-development
#12
REVIEW
Michael Danilchik, Tess Tumarkin
Exosomes are small extracellular vesicles (EVs) secreted by many cell types in both normal and pathogenic circumstances. Because EVs, particularly exosomes, are known to transfer biologically active proteins, RNAs and lipids between cells, they have recently become the focus of intense interest as potential mediators of cell-cell communication, particularly in long-range and juxtacrine signaling events associated with adaptive immune function and progression of cancer. Among the EVs, exosomes appear particularly adapted for long-range delivery of cargoes between cells...
January 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28093475/hippocampal-contribution-to-context-encoding-across-development-is-disrupted-following-early-life-adversity
#13
Hilary K Lambert, Margaret A Sheridan, Kelly A Sambrook, Maya L Rosen, Mary K Askren, Katie A McLaughlin
Context can drastically influence responses to environmental stimuli. For example, a gunshot should provoke a different response at a public park than a shooting range. Little is known about how contextual processing and neural correlates change across human development or about individual differences related to early environmental experiences. Children (N = 60; 8-19 years, 24 exposed to interpersonal violence) completed a context encoding task during fMRI scanning using a delayed match-to-sample design with neutral, happy, and angry facial cues embedded in realistic background scenes...
February 15, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28087202/family-adaptation-to-cerebral-palsy-in-adolescents-a-european-multicenter-study
#14
Audrey Guyard, Susan I Michelsen, Catherine Arnaud, Jerome Fauconnier
BACKGROUND AND AIM: Factors promoting family adaptation to child's disability are poorly studied together. The aim of the study was to describe the family adaptation to disability and to identify determinants associated with using a global theoretical model. MATERIALS AND METHODS: 286 families of teenagers [13-17 years] with cerebral palsy (CP) from 4 European disability registers were included and visited at home. Face to face interviews were performed in order to measure parental distress, perceived impact in various dimensions of family life, family resources and stressors...
January 10, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28026894/by-their-own-devices-invasive-argentine-ants-have-shifted-diet-without-clear-aid-from-symbiotic-microbes
#15
Yi Hu, David A Holway, Piotr Łukasik, Linh Chau, Adam D Kay, Edward G LeBrun, Katie A Miller, Jon G Sanders, Andrew V Suarez, Jacob A Russell
The functions and compositions of symbiotic bacterial communities often correlate with host ecology. Yet cause-and-effect relationships, and the order of symbiont versus host change, remain unclear in the face of ancient symbioses and conserved host ecology. Several groups of ants exemplify this challenge, as their low-nitrogen diets and specialized symbioses appear conserved and ancient. To address whether nitrogen-provisioning symbionts might be important in the early stages of ant trophic shifts we studied bacteria from the Argentine ant, Linepithema humile-an invasive species that has transitioned toward greater consumption of sugar-rich, nitrogen-poor foods in parts of its introduced range...
December 27, 2016: Molecular Ecology
https://www.readbyqxmd.com/read/28001100/content-validity-of-patient-reported-outcome-instruments-used-with-pediatric-patients-with-facial-differences-a-systematic-review
#16
Natasha M Wickert, Karen W Y Wong Riff, Mark Mansour, Christopher R Forrest, Timothy E E Goodacre, Andrea L Pusic, Anne F Klassen
OBJECTIVE:   The aim of this systematic review was to identify patient-reported outcome (PRO) instruments used in research with children/youth with conditions associated with facial differences to identify the health concepts measured. DESIGN:   MEDLINE, EMBASE, CINAHL, and PsycINFO were searched from 2004 to 2016 to identify PRO instruments used in acne vulgaris, birthmarks, burns, ear anomalies, facial asymmetries, and facial paralysis patients. We performed a content analysis whereby the items were coded to identify concepts and categorized as positive or negative content or phrasing...
December 21, 2016: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27988149/a-technique-for-facial-reanimation-the-partial-temporalis-muscle-tendon-transfer-with-a-fascia-lata-sling
#17
Thomas Edward Pidgeon, Radovan Boca, Fazel Fatah
BACKGROUND: This report describes the results of a surgical procedure for facial reanimation. This single-stage technique involves the orthodromic transfer of only a superficial segment of the temporalis tendon. This is extended with fascia lata to achieve elevation of the oral commissure along the desired vector in the paralysed hemi-face. METHODS: A retrospective case note review was performed. Patients' photographs were objectively evaluated with Facial Assessment by Computer Evaluation (FACE) software...
November 10, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27966951/unconventional-o-h%C3%A2-%C3%A2-%C3%A2-c-hydrogen-bonding-and-effects-of-conformational-changes-on-infrared-spectroscopy-of-o-cresol-in-solutions
#18
Xiangai Yuan, Dong Zheng, Xizhang Wang, Pingying Liu, Jing Ma
The unconventional O-H···C intramolecular hydrogen bonding and the effect of conformational changes on IR spectra of o-cresol in aqueous solutions were investigated by using molecular dynamics (MD) simulations, density functional theory (DFT), and experiments. A facial rotational isomerization between global minimum with trans conformation and the cis isomer is predicted to take place in gas phase with a low barrier of about 3.7 kcal/mol through a vertical-like transition state. Upon solvation in aqueous solution, the contents of energetically high-lying vertical and cis conformations of neutral o-cresol are increased to 19% and 57%, respectively, in comparison with those (vertical, 0%; cis, 27%) in vacuum...
December 29, 2016: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/27957603/structure-and-functioning-of-oil-cavities-in-the-shoot-apex-of-metrodorea-nigra-a-st-hil-rutaceae
#19
Silvia Rodrigues Machado, Yve Canaveze, Tatiane Maria Rodrigues
This study investigates the histology and subcellular features of secretory cavities during the development of the shoot apex of Metrodorea nigra A. St.-Hil. in order to better understand the functioning of these glands. This Rutaceae species is a very suitable model for studying secretory cavity life span, since the shoot apex exhibits both dormant and growth stages during its annual cycle. Shoot apices were collected during the dormant and growth stages from populations of M. nigra growing under natural conditions...
December 12, 2016: Protoplasma
https://www.readbyqxmd.com/read/27931764/accuracy-of-remote-burn-scar-evaluation-via-live-video-conferencing-technology
#20
Lawrence Z Cai, Maria Caceres, Mohan Krishna Dangol, Kiran Nakarmi, Shankar Man Rai, James Chang, Nicole S Gibran, Tam N Pham
OBJECTIVE: Telemedicine in outpatient burn care, particularly in burn scar management, may provide cost-effective care and comes highly rated by patients. However, an effective scar scale using both video and photographic elements has not been validated. The purpose of this study is to test the reliability of the Patient and Observer Scar Assessment Scale (POSAS) using live video-conferencing. METHODS: A prospective study was conducted with individuals with healed burn scars in Kathmandu, Nepal...
December 5, 2016: Burns: Journal of the International Society for Burn Injuries
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