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https://www.readbyqxmd.com/read/28436262/private-philanthropy-and-basic-research-in-mid-twentieth-century-america-the-hickrill-chemical-research-foundation
#1
Leon Gortler, Stephen J Weininger
The Hickrill Chemical Research Foundation, located north of New York City on the estate of its patrons, Sylvan and Ruth Alice Norman Weil, had a short (1948-59) but productive life. Ruth Alice Weil received a Ph.D. in organic chemistry in 1947, directed by William von Eggers Doering of Columbia University. She intended that Hickrill contribute to cancer chemotherapy while providing resources for Doering's more speculative research. Ultimately, Doering's commitment to theoretical organic chemistry set Hickrill's research agenda...
April 24, 2017: Ambix
https://www.readbyqxmd.com/read/28436245/book-review-pediatric-cochlear-implantation-learning-and-the-brain-kirk-nancy-m-young-karen-iler-eds-pediatric-cochlear-implantation-learning-and-the-brain-new-york-ny-springer-2016-365-pages-83-129-hardcover-122-kindle
#2
https://www.readbyqxmd.com/read/28435891/detection-of-anaplasma-phagocytophilum-babesia-microti-borrelia-burgdorferi-borrelia-miyamotoi-and-powassan-virus-in-ticks-by-a-multiplex-real-time-reverse-transcription-pcr-assay
#3
Rafal Tokarz, Teresa Tagliafierro, D Moses Cucura, Ilia Rochlin, Stephen Sameroff, W Ian Lipkin
Ixodes scapularis ticks are implicated in transmission of Anaplasma phagocytophilum, Borrelia burgdorferi, Borrelia miyamotoi, Babesia microti, and Powassan virus. We describe the establishment and implementation of the first multiplex real-time PCR assay with the capability to simultaneously detect and differentiate all five pathogens in a single reaction. The application of this assay for analysis of ticks at sites in New York and Connecticut revealed a high prevalence of B. microti in ticks from Suffolk County, NY...
March 2017: MSphere
https://www.readbyqxmd.com/read/28434647/anemia-at-hospital-admission-and-its-relation-to-outcomes-in-patients-with-heart-failure-from-the-polish-cohort-of-2-european-society-of-cardiology-heart-failure-registries
#4
Agata Tymińska, Agnieszka Kapłon-Cieślicka, Krzysztof Ozierański, Michał Peller, Paweł Balsam, Michał Marchel, Maria G Crespo-Leiro, Aldo P Maggioni, Ewa A Jankowska, Jarosław Drożdż, Krzysztof J Filipiak, Grzegorz Opolski
Anemia is a commonly observed co-morbidity in heart failure (HF). The aim of the study was to assess prevalence, risk factors for, and effect of anemia on short- and long-term outcomes in HF. The study included 1,394 Caucasian patients hospitalized for HF, with known hemoglobin concentration on hospital admission, participating in 2 HF registries of the European Society of Cardiology (Pilot and Long-Term). Anemia was defined as hemoglobin concentration of <13 g/dl for men and <12 g/dl for women. Primary end points were (1) all-cause death at 1 year and (2) a composite of all-cause death and rehospitalization for HF at 1 year...
March 29, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28434457/system-changes-to-implement-the-joint-commission-tobacco-treatment-tob-performance-measures-for-improving-the-treatment-of-tobacco-use-among-hospitalized-patients
#5
Donna Shelley, Keith S Goldfeld, Hannah Park, Ana Mola, Ryan Sullivan, Jonathan Austrian
BACKGROUND: In 2012 The Joint Commission implemented new Tobacco Treatment (TOB) performance measures for hospitals. A study evaluated the impact of a hospital-based electronic health record (EHR) intervention on adherence to the revised TOB measures. METHODS: The study was conducted in two acute care hospitals in New York City. Data abstracted from the EHR were analyzed retrospectively from 4,871 smokers discharged between December 2012 and March 2015 to evaluate the impact of two interventions: an order set to prompt clinicians to prescribe pharmacotherapy and a nurse-delivered counseling module that automatically populated the nursing care plan for all smokers...
May 2017: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/28432180/new-york-university-sacks-professor-for-refusing-flu-shot
#6
Margaret McCartney
No abstract text is available yet for this article.
April 21, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28431645/lopez-pm-islam-n-feinberg-a-myers-c-seidl-l-drackett-e-riley-l-mata-a-pinzon-j-benjamin-e-wyka-k-dannefer-r-lopez-j-trinh-shevrin-c-maybank-ka-thorpe-le-a-place-based-community-health-worker-program-feasibility-and-early-outcomes-new-york-city-2015-am-j-prev
#7
https://www.readbyqxmd.com/read/28431590/delays-in-door-to-needle-time-for-acute-ischemic-stroke-in-the-emergency-department-a-comprehensive-stroke-center-experience
#8
Ashkan Mowla, Jordan Doyle, Navdeep S Lail, Hamidreza Rajabzadeh-Oghaz, Christopher Deline, Peyman Shirani, Marilou Ching, Annemarie Crumlish, Deborah A Steck, David Janicke, Elad I Levy, Robert N Sawyer
BACKGROUND: Current American Stroke Association guidelines recommend initiating intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) within 60min of patient arrival, given the benefits of IVT for AIS are time dependent. This study aimed to identify the delaying factors in door-to-needle time (DTN) in the emergency department of one of the largest comprehensive stroke centers in New York State. We also recommended measures to reduce the delays. METHODS: We retrospectively reviewed the medical charts of all AIS patients who received IVT in our emergency department patients between April 1, 2012 and December 31, 2015 to identify those with a DTN time of >60min...
May 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28431133/prediction-of-sudden-and-non-sudden-cardiac-death-in-post-infarction-patients-with-reduced-left-ventricular-ejection-fraction-by-periodic-repolarization-dynamics-madit-ii-substudy
#9
Konstantinos D Rizas, Scott McNitt, Wolfgang Hamm, Steffen Massberg, Stefan Kääb, Wojciech Zareba, Jean-Philippe Couderc, Axel Bauer
Aims: To test the value of Periodic Repolarization Dynamics (PRD), a recently validated electrocardiographic marker of sympathetic activity, as a novel approach to predict sudden cardiac death (SCD) and non-sudden cardiac death (N-SCD) and to improve identification of patients that profit from ICD-implantation. Methods and results: We included 856 post-infarction patients with left-ventricular ejection fraction (LVEF) ≤30% of the MADIT-II trial in sinus rhythm...
April 18, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28430875/progressive-atrophy-of-the-globus-pallidus-primary-atrophy-of-the-pallidal-system-a-system-disease-of-the-paralysis-agitans-type-characterized-by-atrophy-of-the-motor-cells-of-the-corpus-striatum-a-contribution-to-the-function-of-the-corpus-striatum-by-j-ramsay
#10
https://www.readbyqxmd.com/read/28430095/window-of-opportunity-for-new-disease-surveillance-developing-keyword-lists-for-monitoring-mental-health-and-injury-through-syndromic-surveillance
#11
Ursula Lauper, Jian-Hua Chen, Shao Lin
Studies have documented the impact that hurricanes have on mental health and injury rates before, during, and after the event. Since timely tracking of these disease patterns is crucial to disaster planning, response, and recovery, syndromic surveillance keyword filters were developed by the New York State Department of Health to study the short- and long-term impacts of Hurricane Sandy. Emergency department syndromic surveillance is recognized as a valuable tool for informing public health activities during and immediately following a disaster...
April 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28428353/development-of-a-bnp1-32-immunoassay-that-does-not-cross-react-with-probnp
#12
Lynley K Lewis, Sara D Raudsepp, Tim G Yandle, Timothy C Prickett, A Mark Richards
BACKGROUND: Plasma B-type natriuretic peptide (BNP) concentration reflects cardiac dysfunction and assists in determining the diagnosis and prognosis of heart failure (HF). Current BNP assays overestimate circulating bioactive BNP1-32 concentrations as they also detect less active BNP metabolites and proBNP. A specific BNP1-32 assay with negligible cross-reactivity to proBNP and/or BNP metabolites may be advantageous. METHODS: We developed a Luminex-based specific BNP1-32 immunoassay and compared results obtained from 3 other BNP assays (a Luminex-based total-BNP assay, our BNP RIA, and the commercially available Abbott Architect BNP assay) in plasma from 42 patients with HF and 22 healthy controls...
April 20, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28427539/the-role-of-serum-amyloid-a-staining-of-granulomatous-tissues-for-the-diagnosis-of-sarcoidosis
#13
Albert Huho, Llewellyn Foulke, Timothy Jennings, Efstratios Koutroumpakis, Siddhartha Dalvi, Haroon Chaudhry, Amit Chopra, Aakash Modi, Neha Rane, David J Prezant, Christine Sheehan, Recai Yucel, Mehul Patel, Marc A Judson
BACKGROUND: Previous studies demonstrated that SAA staining of sarcoidosis granulomas was qualitatively and quantitatively different from other granulomatous diseases. These data suggest that positive SAA staining of granulomatous tissue may have adequate specificity to establish a diagnosis of sarcoidosis. Our objective was to determine the diagnostic specificity of SAA staining for sarcoidosis relative to other granulomatous disorders. METHODS: Pathological specimens demonstrating granulomatous inflammation were retrospectively identified at one institution, plus 4 specimens were obtained from New York City firefighters with biopsy-confirmed World Trade Center "sarcoidosis-like" pulmonary disease...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28427484/racial-and-ethnic-subgroup-disparities-in-hypertension-prevalence-new-york-city-health-and-nutrition-examination-survey-2013-2014
#14
Kezhen Fei, Jesica S Rodriguez-Lopez, Marcel Ramos, Nadia Islam, Chau Trinh-Shevrin, Stella S Yi, Claudia Chernov, Sharon E Perlman, Lorna E Thorpe
INTRODUCTION: Racial/ethnic minority adults have higher rates of hypertension than non-Hispanic white adults. We examined the prevalence of hypertension among Hispanic and Asian subgroups in New York City. METHODS: Data from the 2013-2014 New York City Health and Nutrition Examination Survey were used to assess hypertension prevalence among adults (aged ≥20) in New York City (n = 1,476). Hypertension was measured (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg or self-reported hypertension and use of blood pressure medication)...
April 20, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28426886/risk-of-stroke-in-chronic-heart-failure-patients-with-preserved-ejection-fraction-but-without-atrial-fibrillation-analysis-of-the-charm-preserved-and-i-preserve-trials
#15
Azmil H Abdul-Rahim, Ana-Cristina Perez, Rachael L MacIsaac, Pardeep S Jhund, Brian L Claggett, Peter E Carson, Michel Komajda, Robert S McKelvie, Michael R Zile, Karl Swedberg, Salim Yusuf, Marc A Pfeffer, Scott D Solomon, Gregory Y H Lip, Kennedy R Lees, John J V McMurray
Aims: The incidence and predictors of stroke in patients with heart failure and preserved ejection fraction (HF-PEF), but without atrial fibrillation (AF), are unknown. We described the incidence of stroke in HF-PEF patients with and without AF and predictors of stroke in those without AF. Methods and results: We pooled data from the CHARM-Preserved and I-Preserve trials. Using Cox regression, we derived a model for stroke in patients without AF in this cohort and compared its performance with a published model in heart failure patients with reduced ejection fraction (HF-REF)-predictive variables: age, body mass index, New York Heart Association class, history of stroke, and insulin-treated diabetes...
March 7, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28426310/a-public-health-approach-to-hepatitis-c-in-an-urban-setting
#16
Fabienne Laraque, Jay K Varma
The clinical consequences of HCV infection are increasing because the population with the highest prevalence of the infection, persons born between 1945 and 1965, is aging. As a result, health care expenditures are expected to increase. Now that a cure for HCV infection is the norm, a public health approach is necessary to identify, link to care, and treat infected persons and prevent new infections. We believe that the success of public health interventions, such as those for tuberculosis, can be translated to HCV infection...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28426302/innovations-in-population-health-surveillance-using-electronic-health-records-for-chronic-disease-surveillance
#17
Sharon E Perlman, Katharine H McVeigh, Lorna E Thorpe, Laura Jacobson, Carolyn M Greene, R Charon Gwynn
With 87% of providers using electronic health records (EHRs) in the United States, EHRs have the potential to contribute to population health surveillance efforts. However, little is known about using EHR data outside syndromic surveillance and quality improvement. We created an EHR-based population health surveillance system called the New York City (NYC) Macroscope and assessed the validity of diabetes, hyperlipidemia, hypertension, smoking, obesity, depression, and influenza vaccination indicators. The NYC Macroscope uses aggregate data from a network of outpatient practices...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28425767/chronic-total-coronary-occlusion-treatment-results
#18
Martin Kirk Christensen, Phillip Fischer Freeman, Jeppe Groendal Rasmussen, Anton Boel Villadsen, Bent Raungaard, Svend Eggert Jensen, Leif Thuesen
OBJECTIVES: To describe the clinical and procedural coronary chronic total occlusion (CTO) treatment results in a Nordic PCI centre during the implementation of a CTO treatment program. DESIGN: In a retrospective registry study, we assessed; (1) indication for the procedure, (2) Canadian Cardiovascular Society angina pectoris score (CCS)/New York Heart Association (NYHA) heart failure score, (3) lesion complexity and (4) adverse events during hospital stay and three months following the index procedure...
April 20, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28425577/postoperative-hemorrhage-and-hospital-revisit-after-transoral-robotic-surgery
#19
Joseph Zenga, Jasmina Suko, Dorina Kallogjeri, Patrik Pipkorn, Brian Nussenbaum, Ryan S Jackson
OBJECTIVES/HYPOTHESIS: To investigate the incidence and complications related to postoperative hemorrhage (POH) after transoral robotic surgery (TORS). STUDY DESIGN: Retrospective review of the State Inpatient Database (SID), the State Ambulatory Surgery Database (SASD), and the State Emergency Department Database (SEDD) from the Healthcare Cost and Utilization Project. METHODS: Patients were identified from the SID, SASD, and SEDD for the states of Florida, New York, and California from 2005 to 2013 who had an International Classification of Diseases, Ninth Edition code for a surgical procedure on the upper aerodigestive tract associated with a code for robotic-assisted surgery...
April 20, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28424545/efficacy-and-safety-of-alcohol-septal-ablation-in-patients-over-65-years-old-with-obstructive-hypertrophic-cardiomyopathy
#20
Laila Cheddadi, Olivier Lairez, Thibault Lhermusier, Francisco Campelo-Parada, Michel Galinier, Didier Carrié, Nicolas Boudou
BACKGROUND: The performance of alcohol septal ablation (ASA) in elderly symptomatic patients with drug-refractory obstructive hypertrophic cardiomyopathy is still to be confirmed. The objective of this study was to compare the efficacy and safety of ASA in patients under and over 65 years old. METHODS AND RESULTS: Fifty-one consecutive patients with obstructive hypertrophic cardio-myopathy who underwent ASA were retrospectively included and reviewed for in-hospital major acute cardiac events and follow-up...
2017: Clinical Interventions in Aging
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