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https://www.readbyqxmd.com/read/29222595/-prostate-cancer-risk-calculator-mobile-applications-apps-a-systematic-review-and-scoring-using-the-validated-user-version-of-the-mobile-application-rating-scale-umars
#1
Ahmed Adam, Julian C Hellig, Marlon Perera, Damien Bolton, Nathan Lawrentschuk
PURPOSE: The use of mobile phone applications (Apps) has modernised the conventional practice of medicine. The diagnostic ability of the current Apps in prostate specific antigen monitoring, and its diagnostic ability within prostate cancer (PCa) risk calculators have not yet been appraised. We aimed to review, rate and assess the everyday functionality, and utility of all the currently available PCa risk calculator Apps. METHODS: A systematic search on iTunes, Google Play Store, Blackberry World and Windows Apps Store, was performed on 23/11/2017, using the search term 'prostate cancer risk calculator'...
December 8, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29222422/reconfigurable-yagi-uda-antenna-based-on-a-silicon-reflector-with-a-solid-state-plasma
#2
Da-Jin Kim, Jang-Soon Park, Cheol Ho Kim, Jae Hur, Choong-Ki Kim, Young-Kyun Cho, Jun-Bong Ko, Bonghyuk Park, Dongho Kim, Yang-Kyu Choi
This paper describes the fabrication and characterization of a reconfigurable Yagi-Uda antenna based on a silicon reflector with a solid-state plasma. The silicon reflector, composed of serially connected p-i-n diodes, forms a highly dense solid-state plasma by injecting electrons and holes into the intrinsic region. When this plasma silicon reflector is turned on, the front-realized gain of the antenna increases by more than 2 dBi beyond 5.3 GHz. To achieve the large gain increment, the structure of the antenna is carefully designed with the aid of semiconductor device simulation and antenna simulation...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29221398/a-multiscale-transport-model-for-non-classical-nanochannel-electroosmosis
#3
Ravi Bhadauria, N R Aluru
We present a multiscale model describing the electroosmotic flow (EOF) in nanoscale channels involving high surface charge liquid-solid interfaces. The departure of the EOF velocity profiles from classical predictions is explained by the non-classical charge distribution in the confined direction including charge inversion, reduced mobility of interfacial counter-ions, and subsequent enhancement of the local viscosity. The excess component of the local solvent viscosity is modeled by the local application of the Fuoss-Onsager theory and the Hubbard-Onsager electro-hydrodynamic equation based dielectric friction theory...
December 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29221386/finite-temperature-dynamics-of-a-holstein-polaron-the-thermo-field-dynamics-approach
#4
Lipeng Chen, Yang Zhao
Combining the multiple Davydov D2 Ansatz with the method of thermo-field dynamics, we study finite temperature dynamics of a Holstein polaron on a lattice. It has been demonstrated, using the hierarchy equations of motion method as a benchmark, that our approach provides an efficient, robust description of finite temperature dynamics of the Holstein polaron in the simultaneous presence of diagonal and off-diagonal exciton-phonon coupling. The method of thermo-field dynamics handles temperature effects in the Hilbert space with key numerical advantages over other treatments of finite-temperature dynamics based on quantum master equations in the Liouville space or wave function propagation with Monte Carlo importance sampling...
December 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29220782/mindfulness-based-interventions-for-chronic-pain-evidence-and-applications
#5
REVIEW
Muhammad Hassan Majeed, Ali Ahsan Ali, Donna M Sudak
Chronic pain is estimated to occur in from 5.5% to 33% of the world's adult population (Gureje et al., 1998). Chronic pain is frequently treated with opiates, which has produced an opiate addiction crisis (Dowell et al., 2016). Several non-pharmacological treatment alternatives can help manage chronic pain. There is moderate evidence that mindfulness-based interventions (MBIs) such as meditation, yoga, and stress reduction lower the perception of pain, increase mobility, improve functioning and well-being. By integrating MBIs and other therapeutic interventions in a multi-disciplinary pain management plan, clinicians can improve treatment outcomes and potentially decrease pain-related medication utilization...
December 5, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29219875/ehealth-interventions-for-parents-in-neonatal-intensive-care-units-a-systematic-review
#6
Justine Dol, Alannah Delahunty-Pike, Sheren Anwar Siani, Marsha Campbell-Yeo
BACKGROUND: As technology becomes increasingly more advanced, particularly video technology and interactive learning platforms, some neonatal intensive care units are embracing electronic health (eHealth) technologies to enhance and expand their family-centered care environments. Despite the emergence of eHealth, there has been a lack of systematic evaluation of its effectiveness thus far. OBJECTIVES: To examine the effect of eHealth interventions used in neonatal intensive care units on parent-related and infant outcomes...
December 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29219859/in-search-of-mobile-applications-for-patients-with-pelvic-floor-disorders
#7
Neha T Sudol, Emily Adams-Piper, Rachel Perry, Felicia Lane, Katherine T Chen
OBJECTIVES: The aims of the study were to identify patient-centered applications (apps) in female pelvic medicine and reconstructive surgery and to evaluate them using a modified APPLICATIONS scoring system. METHODS: A comprehensive list of female pelvic medicine and reconstructive surgery search terms was used to identify apps in the iTunes store. Apps that were eligible for scoring were in English, pertinent to the search term, patient centered, and accurate. All five authors independently evaluated eligible apps using a modified APPLICATIONS scoring system and subsequently reconciled differences by discussion...
December 7, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29219188/toxicity-trial-of-canine-posterior-cricoarytenoid-intramuscular-vincristine-injections
#8
Randal C Paniello, Neel K Bhatt, Rebecca Chernock
OBJECTIVES/HYPOTHESIS: In animal studies, intramuscular vincristine injections have been shown to block reinnervation of the denervated target muscle. This application could be used selectively to influence recovery patterns following injury of recurrent laryngeal nerves (RLNs). However, vincristine is currently Food and Drug Administration approved only for intravenous use. A formal toxicity trial of intramuscular injections was performed. STUDY DESIGN: Animal study...
December 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29218469/discrimination-of-schisandrae-chinensis-fructus-and-schisandrae-sphenantherae-fructus-based-on-fingerprint-profiles-of-hydrophilic-components-by-high-performance-liquid-chromatography-with-ultraviolet-detection
#9
Ryusei Oshima, Akira Kotani, Minpei Kuroda, Kazuhiro Yamamoto, Yoshihiro Mimaki, Hideki Hakamata
High-performance liquid chromatography with ultraviolet detection (HPLC-UV) using 20 mM phosphate mobile phase and an octadecylsilyl column (Triart C18, 150 × 3.0 mm i.d., 3 μm) has been developed for the analysis of hydrophilic compounds in the water extract of Schisandrae Fructus samples. The present HPLC-UV method permits the accurate and precise determination of malic, citric, and protocatechuic acids in the Japanese Pharmacopoeia (JP) Schisandrae Fructus, Schisandrae Chinensis Fructus and Schisandrae Sphenantherae Fructus...
December 7, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/29218073/interconversion-between-free-charges-and-bound-excitons-in-2d-hybrid-lead-halide-perovskites
#10
María C Gélvez-Rueda, Eline M Hutter, Duyen H Cao, Nicolas Renaud, Constantinos C Stoumpos, Joseph T Hupp, Tom J Savenije, Mercouri G Kanatzidis, Ferdinand C Grozema
The optoelectronic properties of hybrid perovskites can be easily tailored by varying their components. Specifically, mixing the common short organic cation (methylammonium (MA)) with a larger one (e.g., butyl ammonium (BA)) results in 2-dimensional perovskites with varying thicknesses of inorganic layers separated by the large organic cation. In both of these applications, a detailed understanding of the dissociation and recombination of electron-hole pairs is of prime importance. In this work, we give a clear experimental demonstration of the interconversion between bound excitons and free charges as a function of temperature by combining microwave conductivity techniques with photoluminescence measurements...
November 30, 2017: Journal of Physical Chemistry. C, Nanomaterials and Interfaces
https://www.readbyqxmd.com/read/29217105/influence-of-muscle-strength-on-early-mobility-in-critically-ill-adult-patients-systematic-literature-review
#11
REVIEW
Audrey R Roberson, Angela Starkweather, Catherine Grossman, Edmund Acevedo, Jeanne Salyer
BACKGROUND: Muscle strength may be one indicator of readiness to mobilize that can be used to guide decisions regarding early mobility efforts and to progressively advance mobilization. OBJECTIVES: To provide a synthesis of current measures of muscle strength in the assessment of early mobilization in critically ill adult patients who are receiving MV therapy. METHODS: Research studies conducted between 2000-2015 were identified using PubMed, CINHAL, MEDLINE, and the Cochrane Database of Systematic Reviews databases using the search terms "muscle strength", "intensive care", "mechanical ventilation" and "muscle weakness"...
January 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29216831/validity-of-mobile-electronic-data-capture-in-clinical-studies-a-pilot-study-in-a-pediatric-population
#12
Belinda von Niederhäusern, Ramon Saccilotto, Sabine Schädelin, Victoria Ziesenitz, Pascal Benkert, Marie-Luise Decker, Anya Hammann, Julia Bielicki, Marc Pfister, Christiane Pauli-Magnus
BACKGROUND: Clinical studies in children are necessary yet conducting multiple visits at study centers remains challenging. The success of "care-at-home" initiatives and remote clinical trials suggests their potential to facilitate conduct of pediatric studies. This pilot aimed to study the feasibility of remotely collecting valid (i.e. complete and correct) saliva samples and clinical data utilizing mobile technology. METHODS: Single-center, prospective pilot study in children undergoing elective tonsillectomy at the University of Basel Children's Hospital...
December 8, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29216765/using-the-intervention-mapping-and-behavioral-intervention-technology-frameworks-development-of-an-mhealth-intervention-for-physical-activity-and-sedentary-behavior-change
#13
Artur Direito, Deirdre Walsh, Moohamad Hinbarji, Rami Albatal, Mark Tooley, Robyn Whittaker, Ralph Maddison
Few interventions to promote physical activity (PA) adapt dynamically to changes in individuals' behavior. Interventions targeting determinants of behavior are linked with increased effectiveness and should reflect changes in behavior over time. This article describes the application of two frameworks to assist the development of an adaptive evidence-based smartphone-delivered intervention aimed at influencing PA and sedentary behaviors (SB). Intervention mapping was used to identify the determinants influencing uptake of PA and optimal behavior change techniques (BCTs)...
December 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29216715/how-strong-is-the-hydrogen-bond-in-hybrid-perovskites
#14
Katrine L Svane, Alexander C Forse, Clare P Grey, Gregor Kieslich, Anthony K Cheetham, Aron Walsh, Keith T Butler
Hybrid organic-inorganic perovskites represent a special class of metal-organic framework where a molecular cation is encased in an anionic cage. The molecule-cage interaction influences phase stability, phase transformations and the molecular dynamics. We examine the hydrogen bonding in four AmBX3 formate perovskites: [Am]Zn(HCOO)3, with Am+ = hydrazinium (NH2NH3+), guanidinium (C(NH2)3+), dimethylammonium (CH3)2NH2+ and azetidinium (CH2)3NH2+. We develop a scheme to quantify the strength of hydrogen bonding in these systems from first-principles, which separates the electrostatic interactions between the amine (Am+) and the BX3- cage...
December 8, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29216583/hplc-ms-ms-analysis-of-mesupron-and-its-application-to-a-pharmacokinetic-study-in-rats
#15
Changmin Park, Joong Gyu Ha, Seungmok Choi, Eunyoung Kim, Keumhan Noh, Beom Soo Shin, Wonku Kang
Mesupron, the first-in-class inhibitor of urokinase-type plasminogen activator (uPA) is known to regulate cell proliferation and migration, and is under investigation for the treatment of metastatic breast cancer. In this study, a quantification method was developed for the determination of mesupron in rat plasma using liquid chromatography with a tandem mass spectrometry (LC-MS/MS). After protein precipitation with acetonitrile including itraconazole (internal standard, IS), the analytes were chromatographed on a reversed phased column with a mobile phase of acetonitrile and water (7:3, v/v, including 0...
December 4, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29216546/adsorption-and-degradation-of-sulfadiazine-and-sulfamethoxazole-in-an-agricultural-soil-system-under-an-anaerobic-condition-kinetics-and-environmental-risks
#16
Genxiang Shen, Yu Zhang, Shuangqing Hu, Hongchang Zhang, Zhejun Yuan, Wei Zhang
Sulfonamides, one of the commonest antibiotics, were widely used on humans and livestock to control pathema and bacterial infections resulting in further environmental risks. The present study evaluated the adsorption and degradation of sulfadiazine (SDZ) and sulfamethoxazole (SMX) in an agricultural soil system under an anaerobic condition. Low sorption coefficients (Kd, 1.22 L kg-1 for SDZ and 1.23 L kg-1 for SMX) obtained from Freundlich isotherms experiment indicated that poor sorption of both antibiotics may pose a high risk to environment due to their high mobility and possibility of entering surface and ground water...
November 30, 2017: Chemosphere
https://www.readbyqxmd.com/read/29215121/stabilizing-benzene-like-planar-n6-rings-to-form-a-single-atomic-honeycomb-ben3-sheet-with-high-carrier-mobility
#17
Xiaoyin Li, Shunhong Zhang, Cunzhi Zhang, Qian Wang
It is a longstanding quest to use the planar N6 ring as a structural unit to build stable atomic sheets. However, unlike C6H6, the neutral N6 ring is unstable due to the strong repulsion of the lone-pair of electrons. Using first-principles calculations and the global structure search method, we show that the N6 unit can be stabilized by the linkage of Be atoms, forming a h-BeN3 honeycomb monolayer, in which the geometry and the π-molecular orbitals of the N6 rings are well kept. This sheet is not only energetically, dynamically and thermally stable, but also can withstand high temperatures up to 1000 K...
December 7, 2017: Nanoscale
https://www.readbyqxmd.com/read/29215046/rapid-and-effective-enrichment-of-mononuclear-cells-from-blood-using-acoustophoresis
#18
Anke Urbansky, Pelle Ohlsson, Andreas Lenshof, Fabio Garofalo, Stefan Scheding, Thomas Laurell
Effective separation methods for fractionating blood components are needed for numerous diagnostic and research applications. This paper presents the use of acoustophoresis, an ultrasound based microfluidic separation technology, for label-free, gentle and continuous separation of mononuclear cells (MNCs) from diluted whole blood. Red blood cells (RBCs) and MNCs behave similar in an acoustic standing wave field, compromising acoustic separation of MNC from RBC in standard buffer systems. However, by optimizing the buffer conditions and thereby changing the acoustophoretic mobility of the cells, we were able to enrich MNCs relative to RBCs by a factor of 2,800 with MNC recoveries up to 88%...
December 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29214806/hierarchical-superhydrophobic-surfaces-with-micropatterned-nanowire-arrays-for-high-efficiency-jumping-droplet-condensation
#19
Rongfu Wen, Shanshan Xu, Dongliang Zhao, Yung-Cheng Lee, Xuehu Ma, Ronggui Yang
Self-propelled droplet jumping on nanostructured superhydrophobic surfaces is of interest for a variety of industrial applications including self-cleaning, water harvesting, power generation, and thermal management systems. However, the uncontrolled nucleation-induced Wenzel state of condensed droplets at large surface subcooling (high heat flux) leads to the formation of large pinned droplets, which results in the flooding phenomena and greatly degrades the heat transfer performance. In this work, we present a novel strategy to manipulate droplet behaviors during the process from the droplet nucleation to growth and departure through a combination of spatially controlling initial nucleation for mobile droplets by closely spaced nanowires and promoting the spontaneous outward movement for rapid removal using micropatterned nanowire arrays...
December 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29214596/preparing-for-the-future-of-rare-diseases
#20
Stephen C Groft, Manuel Posada de la Paz
Members of the rare disease community have devoted significant financial and personnel resources to address the numerous issues surrounding rare diseases. The past has been devoted to developing an emphasis on rare diseases including an emphasis on research studies or locating information on rare diseases and the requirements and limitations of conducting clinical trials with small patient populations. The expanded role of patient advocacy organizations and patient engagement in all aspects of clinical research continues to gain acceptance within the research community...
2017: Advances in Experimental Medicine and Biology
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