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https://www.readbyqxmd.com/read/28718354/mercury-induced-motor-and-sensory-neurotoxicity-systematic-review-of-workers-currently-exposed-to-mercury-vapor
#1
Cheryl A Fields, Jonathan Borak, Elan D Louis
The neurotoxicity of elemental mercury (Hg(0)) is well-recognized, but it is uncertain whether and for how long neurotoxicity persists; among studies that evaluated previously exposed workers, only one examined workers during and also years after exposure ceased. The aim of this review is to document the type, frequency, and dose-relatedness of objective neurological effects in currently exposed mercury workers and thereby provide first approximations of the effects one would have expected in previously exposed workers evaluated during exposure...
July 18, 2017: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/28688836/a-framework-for-identifying-the-adaptations-responsible-for-differences-in-pegboard-times-between-middle-aged-and-older-adults
#2
Landon D Hamilton, Ewan Thomas, Awad M Almuklass, Roger M Enoka
Time to complete two tests of manual dexterity, the 9-hole Peg Test and Grooved Pegboard Test, increases with advancing age. However, the adaptations responsible for the differences in pegboard times between middle-aged and older adults are largely unknown. Potential mechanisms include neuromuscular characteristics, cognitive function, and cutaneous sensation. To provide a tractable framework to address these gaps in knowledge, the purpose of the current study was to identify the latent variables underlying age-associated differences in time to complete the 9-hole and grooved pegboard tests...
July 5, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28660096/da-vinci-xi-robot-assisted-penetrating-keratoplasty
#3
Jimmy Chammas, Arnaud Sauer, Joëlle Pizzuto, Fabienne Pouthier, David Gaucher, Jacques Marescaux, Didier Mutter, Tristan Bourcier
PURPOSE: This study aims (1) to investigate the feasibility of robot-assisted penetrating keratoplasty (PK) using the new Da Vinci Xi Surgical System and (2) to report what we believe to be the first use of this system in experimental eye surgery. METHODS: Robot-assisted PK procedures were performed on human corneal transplants using the Da Vinci Xi Surgical System. After an 8-mm corneal trephination, four interrupted sutures and one 10.0 monofilament running suture were made...
June 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28643066/solving-the-surgeon-ergonomic-crisis-with-surgical-exosuit
#4
Shanglei Liu, Daniel Hemming, Ran B Luo, Jessica Reynolds, Jonathan C Delong, Bryan J Sandler, Garth R Jacobsen, Santiago Horgan
INTRODUCTION: The widespread adoption of laparoscopic surgery has put new physical demands on the surgeon leading to increased musculoskeletal disorders and injuries. Shoulder, back, and neck pains are among the most common complaints experienced by laparoscopic surgeons. Here, we evaluate the feasibility and efficacy of a non-intrusive progressive arm support exosuit worn by surgeons under the sterile gown to reduce pain and fatigue during surgery. METHODS AND PROCEDURES: This is a prospective randomized crossover study approved by the Internal Review Board (IRB)...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28639038/characteristics-predicting-laparoscopic-skill-in-medical-students-nine-years-experience-in-a-single-center
#5
Tsutomu Nomura, Takeshi Matsutani, Nobutoshi Hagiwara, Itsuo Fujita, Yoshiharu Nakamura, Yoshikazu Kanazawa, Hiroshi Makino, Yasuhiro Mamada, Terumichi Fujikura, Masao Miyashita, Eiji Uchida
INTRODUCTION: We introduced laparoscopic simulator training for medical students in 2007. This study was designed to identify factors that predict the laparoscopic skill of medical students, to identify intergenerational differences in abilities, and to estimate the variability of results in each training group. Our ultimate goal was to determine the optimal educational program for teaching laparoscopic surgery to medical students. METHODS: Between 2007 and 2015, a total of 270 fifth-year medical students were enrolled in this observational study...
June 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28637819/long-interval-intracortical-inhibition-is-asymmetric-in-young-but-not-older-adults
#6
Ann-Maree Vallence, Elizabeth Smalley, Peter Drummond, Geoff Hammond
Aging is typically accompanied by a decline in manual dexterity and handedness; the dominant hand executes tasks of manual dexterity more quickly and accurately than the non-dominant hand in younger adults, but this advantage typically declines with age. Age-related changes in intracortical inhibitory processes might play a role in the age-related decline in manual dexterity. Long interval intracortical inhibition (LICI) is asymmetric in young adults, with more sensitive and more powerful LICI circuits in the dominant hemisphere than the non-dominant hemisphere...
June 21, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28629845/role-of-primary-motor-cortex-in-the-control-of-manual-dexterity-assessed-via-sequential-bilateral-lesion-in-the-adult-macaque-monkey-a-case-study
#7
Julie Savidan, Mélanie Kaeser, Abderraouf Belhaj-Saïf, Eric Schmidlin, Eric M Rouiller
From a case study, we describe the impact of unilateral lesion of the hand area in the primary motor cortex (M1) on manual dexterity and the role of the intact contralesional M1 in long-term functional recovery. An adult macaque monkey performed two manual dexterity tasks: (i) "modified Brinkman board" task, assessed simple precision grip versus complex precision grip, the latter involved a hand postural adjustment; (ii) "modified Klüver board" task, assessed movements ranging from power grip to precision grip, pre-shaping and grasping...
June 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/28627718/motor-performance-in-children-with-noonan-syndrome
#8
Ellen A Croonen, Marlou Essink, Ineke van der Burgt, Jos M Draaisma, Cees Noordam, Maria W G Nijhuis-van der Sanden
Although problems with motor performance in daily life are frequently mentioned in Noonan syndrome, the motor performance profile has never been systematically investigated. The aim of this study was to examine whether a specific profile in motor performance in children with Noonan syndrome was seen using valid norm-referenced tests. The study assessed motor performance in 19 children with Noonan syndrome (12 females, mean age 9 years 4 months, range 6 years 1 month to 11 years and 11 months, SDS 1 year and 11 months)...
June 19, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28604171/abnormal-eeg-responses-to-tms-during-the-cortical-silent-period-are-associated-with-hand-function-in-chronic-stroke
#9
Whitney A Gray, Jacqueline A Palmer, Steven L Wolf, Michael R Borich
BACKGROUND: Abnormal brain excitability influences recovery after stroke at which time a prolonged transcranial magnetic stimulation (TMS)-induced electromyographic silent period is thought to reflect abnormal inhibitory interneuron excitability. Cortical excitability can be probed directly during the silent period using concurrent electroencephalography (EEG) of TMS-evoked responses. OBJECTIVE: The primary study objectives were to characterize TMS-evoked cortical potentials (TEPs) using EEG and to investigate associations with persistent hand and arm motor dysfunction in individuals with chronic stroke...
July 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/28603509/emerging-trends-in-the-multimodal-nature-of-cognition-touch-and-handedness
#10
REVIEW
Miriam Ittyerah
Advances in tactile cognition and haptics have increased our understanding of the multimodal nature of touch. Haptic data is mostly confined to human performance arising from the flexibility and dexterity of the fingers used to discriminate shapes and objects. Studies with infants indicate that recognition of objects either seen or held in the hand is possible during early periods of infancy. Evidence indicates performance differences between the hands decrease over periods of development, reflecting maturation of the cortical brain system supporting motor skills...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28595090/associations-between-motor-proficiency-in-children-with-history-of-maltreatment-and-living-in-social-economically-vulnerability
#11
Rodrigo Flores Sartori, Paulo Felipe Ribeiro Bandeira, Glauber Carvalho Nobre, Maria Helena da Silva Ramalho, Nadia Cristina Valentini
Maltreatment and living in poor socioeconomic conditions during childhood may implicate in deficits on motor proficiency, nevertheless, the literature on this issue is still scarce. The goal of the study was to investigate the possible associations among manual dexterity, aiming and catching tasks, and balance tasks for children who suffers maltreatment and lived in social vulnerability. Eighty-two (82) children (08-09 years old) participated in the study. Forty-one (41) belong to the (SEV-M Group) children living in social economic vulnerability and were previously maltreated (lived in foster homes as results of parental neglect and domestic violence), and 41 belong to the (SEV Group) children living in social economical vulnerability with no history of childhood maltreatment...
June 5, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28589732/functional-factors-that-are-important-correlates-to-physical-activity-in-people-with-multiple-sclerosis-a-pilot-study
#12
Nathaniel B Ketelhut, John H Kindred, Richard E Pimentel, Ann M Hess, Brian L Tracy, Raoul F Reiser, Thorsten Rudroff
PURPOSE: Identify functional factors that are important correlates to physical activity levels among people with multiple sclerosis. METHODS: A total of eight functional tests were conducted and physical activity was objectively measured (Actigraph GT3X accelerometer) for one week in 34 people with multiple sclerosis. A corrected Akaike Information Criterion analysis was performed to identify the strongest correlates with moderate-to-vigorous physical activity, total activity and sedentary time...
June 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28587056/tolerance-of-the-brachial-plexus-to-high-dose-reirradiation
#13
Allen M Chen, Taeko Yoshizaki, Maria A Velez, Argin G Mikaeilian, Sophia Hsu, Minsong Cao
PURPOSE: To study the tolerance of the brachial plexus to high doses of radiation exceeding historically accepted limits by analyzing human subjects treated with reirradiation for recurrent tumors of the head and neck. METHODS AND MATERIALS: Data from 43 patients who were confirmed to have received overlapping dose to the brachial plexus after review of radiation treatment plans from the initial and reirradiation courses were used to model the tolerance of this normal tissue structure...
May 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28578819/home-based-training-for-dexterity-in-parkinson-s-disease-a-randomized-controlled-trial
#14
Tim Vanbellingen, Thomas Nyffeler, Julia Nigg, Jorina Janssens, Johanna Hoppe, Tobias Nef, René M Müri, Erwin E H van Wegen, Gert Kwakkel, Stephan Bohlhalter
BACKGROUND: Patients with Parkinson's disease exhibit disturbed manual dexterity. This impairment leads to difficulties in activities of daily living, such as buttoning a shirt or hand-writing. The aim of the present study was to investigate the effectiveness of a home-based dexterity program on fine motor skills in a single-blinded, randomized controlled trial, in patients with Parkinson's disease. METHODS: One hundred and three patients with Parkinson's disease (aged between 48 and 80 years, Hoehn & Yahr stage I-IV) were randomized to either a home-based dexterity program (HOMEDEXT) or Thera-band program...
May 25, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28567537/hiv-1-associated-neurocognitive-disorder-epidemiology-pathogenesis-diagnosis-and-treatment
#15
REVIEW
Christian Eggers, Gabriele Arendt, Katrin Hahn, Ingo W Husstedt, Matthias Maschke, Eva Neuen-Jacob, Mark Obermann, Thorsten Rosenkranz, Eva Schielke, Elmar Straube
The modern antiretroviral treatment of human immunodeficiency virus (HIV-1) infection has considerably lowered the incidence of opportunistic infections. With the exception of the most severe dementia manifestations, the incidence and prevalence of HIV-associated neurocognitive disorders (HAND) have not decreased, and HAND continues to be relevant in daily clinical practice. Now, HAND occurs in earlier stages of HIV infection, and the clinical course differs from that before the widespread use of combination antiretroviral treatment (cART)...
May 31, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28548032/impact-of-age-sex-socioeconomic-status-and-physical-activity-on-associated-movements-and-motor-speed-in-preschool-children
#16
Tanja H Kakebeeke, Annina E Zysset, Nadine Messerli-Bürgy, Aziz Chaouch, Kerstin Stülb, Claudia S Leeger-Aschmann, Einat A Schmutz, Amar Arhab, Valentin Rousson, Susi Kriemler, Simone Munsch, Jardena J Puder, Oskar G Jenni
INTRODUCTION: Young children generally show contralateral associated movements (CAMs) when they are making an effort to perform a unimanual task. CAM and motor speed are two relevant aspects of motor proficiency in young children. These CAMs decrease over age, while motor speed increases. As both CAM and motor speed are associated with age, we were interested in whether these two parameters are also linked with each other. METHOD: In this study, three manual dexterity tasks with the dominant and nondominant hands (pegboard, repetitive hand, and repetitive finger tasks) were used to investigate the effect of covariates (age, sex, socioeconomic status, total physical activity) on both motor speed and CAMs in preschool children...
May 26, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28543714/motor-function-domains-in-alternating-hemiplegia-of-childhood
#17
Melanie Masoud, Kelly Gordon, Amanda Hall, Joan Jasien, Kara Lardinois, Julie Uchitel, Melissa Mclean, Lyndsey Prange, Jeffrey Wuchich, Mohamad A Mikati
AIM: To characterize motor function profiles in alternating hemiplegia of childhood, and to investigate interrelationships between these domains and with age. METHOD: We studied a cohort of 23 patients (9 males, 14 females; mean age 9y 4mo, range 4mo-43y) who underwent standardized tests to assess gross motor, upper extremity motor control, motor speech, and dysphagia functions. RESULTS: Gross Motor Function Classification System (GMFCS), Gross Motor Function Measure-88 (GMFM-88), Manual Ability Classification System (MACS), and Revised Melbourne Assessment (MA2) scales manifested predominantly mild impairments; motor speech, moderate to severe; Modified Dysphagia Outcome and Severity Scale (M-DOSS), mild-to moderate deficits...
August 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28542319/shared-and-differentiated-motor-skill-impairments-in-children-with-dyslexia-and-or-attention-deficit-disorder-from-simple-to-complex-sequential-coordination
#18
Marie-Ève Marchand-Krynski, Olivier Morin-Moncet, Anne-Marie Bélanger, Miriam H Beauchamp, Gabriel Leonard
Dyslexia and Attention deficit disorder (AD) are prevalent neurodevelopmental conditions in children and adolescents. They have high comorbidity rates and have both been associated with motor difficulties. Little is known, however, about what is shared or differentiated in dyslexia and AD in terms of motor abilities. Even when motor skill problems are identified, few studies have used the same measurement tools, resulting in inconstant findings. The present study assessed increasingly complex gross motor skills in children and adolescents with dyslexia, AD, and with both Dyslexia and AD...
2017: PloS One
https://www.readbyqxmd.com/read/28539095/effectiveness-of-non-fluoride-and-fluoride-dentifrices-for-denture-hygiene
#19
Gökçe Meriç, Meryem Güvenir, Kaya Suer
OBJECTIVE: To compare the effectiveness of commonly used herbal/non-fluoride with fluoride dentifrices in order to eliminate pathogenic oral microorganisms from denture base material. MATERIALS AND METHODS: Heat-polymerized acrylic resin specimens (n = 288) were divided into three groups and each group inoculated with three various microorganisms (n = 96 for each) Candida albicans, Staphylococcus aureus and Pseudomonas aeruginosa (P. aeruginosa). Contaminated specimens were randomly assigned to the application of six herbal/non-fluoride and three fluoride dentifrices...
May 24, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28532877/task-based-mirror-therapy-enhances-ipsilesional-motor-functions-in-stroke-a-pilot-study
#20
Kamal Narayan Arya, Shanta Pandian, Dharmendra Kumar
OBJECTIVE: To examine the effect of Mirror therapy (MT) on dexterity, coordination, and muscle strength of the less-affected upper limb in stroke. DESIGN: Pre-test post-test, single group, experimental design. SETTING: Rehabilitation institute. PARTICIPANTS: Post-stroke hemiparetic chronic subjects (N = 21). INTERVENTIONS: Forty sessions of MT using various tasks in addition to the conventional rehabilitation...
April 2017: Journal of Bodywork and Movement Therapies
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