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https://www.readbyqxmd.com/read/29439364/enhancement-of-motor-learning-by-focal-intermittent-theta-burst-stimulation-itbs-of-either-the-primary-motor-m1-or-somatosensory-area-s1-in-healthy-human-subjects
#1
Thomas Platz, Marija Adler-Wiebe, Sybille Roschka, Martin Lotze
BACKGROUND: Motor rehabilitation after brain damage relies on motor re-learning as induced by specific training. Non-invasive brain stimulation (NIBS) can alter cortical excitability and thereby has a potential to enhance subsequent training-induced learning. Knowledge about any priming effects of NIBS on motor learning in healthy subjects can help to design targeted therapeutic applications in brain-damaged subjects. OBJECTIVE: To examine whether complex motor learning in healthy subjects can be enhanced by intermittent theta burst stimulation (iTBS) to primary motor or sensory cortical areas...
2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29423680/changes-in-upper-extremity-function-adl-and-hrqol-in-colorectal-cancer-patients-after-the-first-chemotherapy-cycle-with-oxaliplatin-a-prospective-single-center-observational-study
#2
Ami Tabata, Masashi Kanai, Takahiro Horimatsu, Tadao Tsuboyama, Kanae Matsushima, Toshihiro Kato
PURPOSE: Oxaliplatin, an important chemotherapeutic agent in colorectal cancer, causes chemotherapy-induced peripheral neuropathy (CIPN), for which prophylactic or therapeutic interventions are lacking. We aimed to investigate changes in upper extremities, activities of daily living (ADL), and health-related quality of life (HRQoL) parameters after the first chemotherapy cycle. METHODS: Thirty-eight colorectal cancer patients scheduled to receive the leucovorin, 5'-fluorouracil, oxaliplatin (FOLFOX) therapy or the capecitabine, oxaliplatin (CAPOX) therapy, participated...
February 8, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29420360/effectiveness-of-a-single-session-of-dual-transcranial-direct-current-stimulation-in-combination-with-upper-limb-robotic-assisted-rehabilitation-in-chronic-stroke-patients-a-randomized-double-blind-cross-over-study
#3
Stéphanie Dehem, Maxime Gilliaux, Thierry Lejeune, Emmanuelle Delaunois, Paul Mbonda, Yves Vandermeeren, Christine Detrembleur, Gaëtan Stoquart
The impact of transcranial direct current stimulation (tDCS) is controversial in the neurorehabilitation literature. It has been suggested that tDCS should be combined with other therapy to improve their efficacy. To assess the effectiveness of a single session of upper limb robotic-assisted therapy (RAT) combined with real or sham-tDCS in chronic stroke patients. Twenty-one hemiparetic chronic stroke patients were included in a randomized, controlled, cross-over double-blind study. Each patient underwent two sessions 7 days apart in a randomized order: (a) 20 min of real dual-tDCS associated with RAT (REAL+RAT) and (b) 20 min of sham dual-tDCS associated with RAT (SHAM+RAT)...
February 7, 2018: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/29390334/degeneration-of-the-corticofugal-tract-from-the-secondary-motor-area-in-a-parkinson-s-disease-patient-with-limb-kinetic-apraxia-a-case-report
#4
Han Do Lee, Min Cheol Chang
RATIONALE: In this case report, we describe a Parkinson's disease (PD) patient with limb-kinetic apraxia (LKA) in whom degeneration of the corticofugal tract (CFT) from the supplementary motor area (SMA) was observed in diffusion tensor tractography (DTT). PATIENT CONCERNS: A 63-year-old woman presented with a loss of dexterity in both upper extremities, which indicated LKA, and typical PD-related symptoms, including a gait disturbance with a short step, resting tremor in both upper extremities, and rigidity, and these symptoms had been present for 2 years...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29389940/spiral-tracing-on-a-touchscreen-is-influenced-by-age-hand-implement-and-friction
#5
Brittany D Heintz, Kevin G Keenan
Dexterity impairments are well documented in older adults, though it is unclear how these influence touchscreen manipulation. This study examined age-related differences while tracing on high- and low-friction touchscreens using the finger or stylus. 26 young and 24 older adults completed an Archimedes spiral tracing task on a touchscreen mounted on a force sensor. Root mean square error was calculated to quantify performance. Root mean square error increased by 29.9% for older vs. young adults using the fingertip, but was similar to young adults when using the stylus...
2018: PloS One
https://www.readbyqxmd.com/read/29366905/hand-dysfunction-in-type-2-diabetes-mellitus-systematic-review-with-meta-analysis
#6
REVIEW
Shubha Gundmi, Arun G Maiya, Anil K Bhat, N Ravishankar, Manjunatha H Hande, K V Rajagopal
BACKGROUND: People with type 2 diabetes mellitus frequently show complications in feet and hands. However, the literature has mostly focused on foot complications. The disease can affect the strength and dexterity of the hands, thereby reducing function. OBJECTIVES: This systematic review and meta-analysis focused on identifying the existing evidence on how type 2 diabetes mellitus affects hand strength, dexterity and function. METHODS: We searched MEDLINE via PubMed, CINHAL, Scopus and Web of Science, and the Cochrane central register of controlled trials for reports of studies of grip and pinch strength as well as hand dexterity and function evaluated by questionnaires comparing patients with type 2 diabetes mellitus and healthy controls that were published between 1990 and 2017...
January 27, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29360589/virtual-reality-glasses-and-eye-hands-blind-technique-for-microsurgical-training-in-neurosurgery
#7
Joham Choque-Velasquez, Roberto Colasanti, Juhani Collan, Riina Kinnunen, Behnam Rezai Jahromi, Juha Hernesniemi
OBJECTIVE: Microsurgical skills and eye-hand coordination need a continuous training to be developed and refined. However, well-equipped microsurgical laboratories are not so widespread as their setting-up is very expensive. Herein, we present a novel microsurgical training system which requires a high-resolution personal computer screen, smartphones and virtual reality glasses. METHODS: A smartphone, which is placed on a holder at a height of about 15-20 cm from the surgical target field, is used as the webcam of the computer...
January 19, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29336812/enhancing-surgical-performance-by-adopting-expert-musicians-practice-and-performance-strategies
#8
Mei Rui, Jeffrey E Lee, Jean-Nicolas Vauthey, Claudius Conrad
BACKGROUND: Surgery is a performing art-each surgical procedure is a live performance that has immediate and irreversible consequences for both the performer and the audience. Surgeons operate with surgical instruments, whereas musicians perform with musical instruments. Both perform in high-stress, high-risk work environments, where small errors in motor performance or judgment can have immediate negative consequences. While there is abundant literature on musical performance and their impact on outcome, little similar research has been published in the field of surgery...
January 11, 2018: Surgery
https://www.readbyqxmd.com/read/29327599/motor-skills-cognition-and-work-performance-of-people-with-severe-mental-illness
#9
Lena Lipskaya-Velikovsky, Dikla Elgerisi, Adam Easterbrook, Navah Z Ratzon
PURPOSE: Employment offers many benefits to people with mental illness, yet their employment rate is much lower than that of the general population. We investigated the effect of work-related motor skills, neurocognition, and job attitudes on the work performance of people with mental illness, comparing those working in sheltered workshops, with controls working in similar jobs. METHODS: Twenty-nine adults with severe mental illness and 27 controls matched by gender and age were enrolled into the study using convenience sampling...
January 12, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29316895/daily-repetitive-sensory-stimulation-of-the-paretic-hand-for-the-treatment-of-sensorimotor-deficits-in-patients-with-subacute-stroke-reset-a-randomized-sham-controlled-trial
#10
Jan C Kattenstroth, Tobias Kalisch, Matthias Sczesny-Kaiser, Wolfgang Greulich, Martin Tegenthoff, Hubert R Dinse
BACKGROUND: Repetitive sensory stimulation (RSS) adapts the timing of stimulation protocols used in cellular studies to induce synaptic plasticity. In healthy subjects, RSS leads to widespread sensorimotor cortical reorganization paralleled by improved sensorimotor behavior. Here, we investigated whether RSS reduces sensorimotor upper limb impairment in patients with subacute stroke more effectively than conventional therapy. METHODS: A single-blinded sham-controlled clinical trial assessed the effectiveness of RSS in treating sensorimotor deficits of the upper limbs...
January 9, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29316821/evaluation-of-a-functional-hand-orthosis-combined-with-electrical-stimulation-adjunct-to-arm-hand-rehabilitation-in-subacute-stroke-patients-with-a-severely-to-moderately-affected-hand-function
#11
Johan Anton Franck, Rob Johannes Elise Marie Smeets, Henk Alexander Maria Seelen
PURPOSE: To investigate the usability and effectiveness of a functional hand orthosis, combined with electrical stimulation adjunct to therapy-as-usual, on functional use of the moderately/severely impaired hand in sub-acute stroke patients. MATERIALS AND METHODS: Single case experiment (A-B-A'-design) involving eight sub-acute stroke patients. The functional hand orthosis and electrical stimulation were used for six weeks, four days/week, 45'/day. OUTCOME MEASURES: Action_Research_Arm_Test, Intrinsic_Motivation_Inventory...
January 9, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29305534/the-role-of-human-primary-motor-cortex-in-the-production-of-skilled-finger-sequences
#12
Atsushi Yokoi, Spencer A Arbuckle, Jörn Diedrichsen
Human primary motor cortex (M1) is essential for producing dexterous hand movements. While distinct subpopulations of neurons are activated during single finger movements, it remains unknown whether M1 also represents sequences of multiple finger movements. Using novel multivariate fMRI analysis techniques and combining evidence from both 3T and 7T fMRI data, we found that after 5 days of intense practice, premotor and parietal areas encoded the different movement sequences. There was little or no evidence for a sequence representation in M1...
January 5, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29303031/the-relationship-between-hand-function-and-overlapping-motor-representations-of-the-hands-in-the-contralesional-hemisphere-in-unilateral-spastic-cerebral-palsy
#13
Michelle Marneweck, Hsing-Ching Kuo, Ana R P Smorenburg, Claudio L Ferre, Veronique H Flamand, Disha Gupta, Jason B Carmel, Yannick Bleyenheuft, Andrew M Gordon, Kathleen M Friel
BACKGROUND: In many children with unilateral spastic cerebral palsy (USCP), the corticospinal tract to the affected hand atypically originates in the hemisphere ipsilateral to the affected hand. Such ipsilateral connectivity is on average a predictor of poor hand function. However, there is high variability in hand function in these children, which might be explained by the complexity of motor representations of both hands in the contralesional hemisphere. OBJECTIVE: To measure the link between hand function and the size and excitability of motor representations of both hands, and their overlap, in the contralesional hemisphere of children with USCP...
January 1, 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29287994/exploring-the-existence-of-better-hands-for-manipulation-than-the-human-hand-based-on-hand-proportions
#14
Di Hu, Cai-Hua Xiong, Ming-Jin Liu
Human exhibits the most dexterous manual manipulation among the anthropoids. The sophisticated dexterity of human hand has been linked to its distinctive morphology compared to the nonhuman anthropoids. The human hand is derived from the ancestral hands after longtime evolution. However, there are more possible morphologies that the hands could take during the evolutionary process. It remains unknown whether better hands for manipulation than the human hand exist among these possible hands. To answer the question, the relationship between the manipulative capability and hand morphology need to be investigated in the region of more possible hands...
December 26, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29286827/the-role-of-anxiety-in-simulation-based-dexterity-and-overall-performance-does-it-really-matter
#15
Fatema Dhaif, Georgios Paparoidamis, Michail Sideris, John Hanrahan, Efstratia-Maria Georgopoulou, Ismini Tsagkaraki, Nikolaos Staikoglou, Ferha Saeed, Theodoros Michail, Anastasios Tzavelas, Efstathios Kenanidis, Michael Potoupnis, Eleftherios Tsiridis, Apostolos Papalois
BACKGROUND: Essential Skills in the Management of Surgical Cases (ESMSC) is an international undergraduate surgical masterclass which combines ex vivo, dry lab and high fidelity in vivo simulation-based learning (SBL). It consists of 32 stations of skills-based learning, including open reduction internal fixation (ORIF) of fractures. Current literature suggests early involvement in skills-based learning at the undergraduate level is vital. AIMS: To compare students' dexterity and skills-based performance with demographic and educational background parameters...
December 29, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29284747/motor-dexterity-and-strength-depend-upon-integrity-of-the-attention-control-system
#16
Paul Rinne, Mursyida Hassan, Cristina Fernandes, Erika Han, Emma Hennessy, Adam Waldman, Pankaj Sharma, David Soto, Robert Leech, Paresh A Malhotra, Paul Bentley
Attention control (or executive control) is a higher cognitive function involved in response selection and inhibition, through close interactions with the motor system. Here, we tested whether influences of attention control are also seen on lower level motor functions of dexterity and strength-by examining relationships between attention control and motor performance in healthy-aged and hemiparetic-stroke subjects (n = 93 and 167, respectively). Subjects undertook simple-tracking, precision-hold, and maximum force-generation tasks, with each hand...
December 28, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29280207/blocking-energy-loss-pathways-for-ideal-fluorescent-organic-light-emitting-diodes-with-thermally-activated-delayed-fluorescent-sensitizers
#17
Dongdong Zhang, Xiaozeng Song, Minghan Cai, Lian Duan
Organic light-emitting diodes (OLEDs) based on thermally activated delayed fluorescence-sensitized fluorescence (TSF) offer the possibility of attaining an ultimate high efficiency with low roll-off utilizing noble-metal free, easy-to-synthesize, pure organic fluorescent emitters. However, the performances of TSF-OLEDs are still unsatisfactory. Here, TSF-OLEDs with breakthrough efficiencies even at high brightnesses by suppressing the competitive deactivation processes, including direct charge recombination on conventional fluorescent dopants (CFDs) and Dexter energy transfer from the host to the CFDs, are demonstrated...
December 27, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29278998/neurocognitive-and-fine-motor-deficits-in-asymptomatic-adolescents-during-the-subacute-period-after-concussion
#18
Richard J Servatius, Kevin M Spiegler, Justin D Handy, Kevin C H Pang, Jack W Tsao, Catherine A Mazzola
Adolescents are at high risk for sustaining concussions. There is considerable controversy regarding the sensitivity of neurocognitive tests to detect and track dysfunction in the aftermath of concussion. Two neurocognitive test batteries were compared during the subacute phase of recovery from concussion to determine sensitivity to concussion. Adolescents (ages 11-17 years) with a concussion diagnosis (8 males, 7 females, 9-69 days after injury) were recruited through a concussion clinic and compared to community non-concussed volunteers (11 males, 3 females)...
December 26, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29276499/usability-of-videogame-based-dexterity-training-in-the-early-rehabilitation-phase-of-stroke-patients-a-pilot-study
#19
Tim Vanbellingen, Suzanne J Filius, Thomas Nyffeler, Erwin E H van Wegen
Background: Approximately 70-80% of stroke survivors have limited activities of daily living, mainly due to dexterous problems. Videogame-based training (VBT) along with virtual reality seems to be beneficial to train upper limb function. Objective: To evaluate the usability of VBT using the Leap Motion Controller (LMC) to train fine manual dexterity in the early rehabilitation phase of stroke patients as an add-on to conventional therapy. Additionally, this study aimed to estimate the feasibility and potential efficacy of the VBT...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29274767/development-of-corticospinal-motor-excitability-and-cortical-silent-period-from-mid-childhood-to-adulthood-a-navigated-tms-study
#20
Laura Säisänen, Petro Julkunen, Timo Lakka, Virpi Lindi, Mervi Könönen, Sara Määttä
OBJECTIVES: We characterized the maturation of the excitability of the motor cortex and corticospinal tract from childhood to adulthood using electric field (EF) navigated TMS and correlated the results with manual dexterity. METHODS: Both hemispheres of healthy right-handed children (6-9 years, n=10), preadolescents (10-12 years, n=13), adolescents (14-17 years, n=12) and young adults (22-34 years, n=12) of both genders were examined. The optimal cortical representation site and resting motor threshold (rMT) were determined for the abductor pollicis brevis muscle...
December 20, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
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