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Contact lens keratitis

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https://www.readbyqxmd.com/read/27902509/paecilomyces-lilacinus-keratitis-in-a-soft-contact-lens-wearer
#1
Rosa Monno, Giovanni Alessio, Silvana Guerriero, Carmen Capolongo, Carla Calia, Luciana Fumarola, Carlo Pazzani, Anna Di Taranto, Giuseppe Miragliotta
We describe a case of keratitis caused by Paecilomyces lilacinus in a contact lens wearer with a history of diabetes.
November 29, 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/27874294/dacryoadenitis-and-extraocular-muscle-inflammation-associated-with-contact-lens-related-acanthamoeba-keratitis-a-case-report-and-review-of-the-literature
#2
Tomris Sengor, Erdal Yuzbasioglu, Sevda Aydın Kurna, Murat Irkec, Ahmet Altun, Kubra Kökcen, Nazli Gul Yalcin
The present report discusses a new case of dacryoadenitis with extraocular muscle inflammation associated with Acanthamoeba keratitis (AK) in a contact lens wearer. A 41-year-old male, who has worn silicone hydrogel contact lenses on an extended basis for about 10 years, attended with the complaints of vision disturbance, hyperemia, and pain in his right eye. His history revealed that 1.5 month ago, he had been diagnosed with allergic conjunctivitis and had used steroid eye drops. Biomicroscopic examination revealed eyelid edema, chemosis, and ring infiltration, radial keratoneuritis and an epithelial defect in the cornea...
November 22, 2016: Orbit
https://www.readbyqxmd.com/read/27870779/painless-acanthamoeba-keratitis-with-normal-vision
#3
Pui Wai Rachel Kwok, Ka Wai Kam, Vishal Jhanji, Alvin L Young
PURPOSE: To report an atypical case of contact lens-related Acanthamoeba keratitis. CASE REPORT: A 15-year-old secondary school female student with a history of soft contact lens wear was referred to our hospital by a private general practitioner for management of right eye redness and discomfort for 2 weeks. Upon examination, the best-corrected visual acuity was 20/20 and 20/16 for her right and left eyes, respectively. There was diffuse radial keratoneuritis noted in the cornea of her right eye without any associated epithelial defect...
November 19, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27826683/aspergillus-flavus-keratitis-experience-of-a-tertiary-eye-clinic-in-turkey
#4
Elif Erdem, Meltem Yagmur, Hazal Boral, Macit Ilkit, Reha Ersoz, Seyedmojtaba Seyedmousavi
We investigated the clinical and mycological characteristics of four cases of mycotic keratitis caused by Aspergillus flavus that occurred from July 2014 to May 2015 at Çukurova University Hospital, Adana, Turkey. In a 10-month period, a total of 64 corneal smear/scrapings were examined from patients with suspected mycotic keratitis. Fungal cultures were positive in six of these patients, indicating a 9.4% incidence of mycotic keratitis in this region, including four cases of A. flavus and two cases of Fusarium spp...
November 8, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27806431/contact-lens-wear-is-intrinsically-inflammatory
#5
REVIEW
Nathan Efron
Eye-care practitioners typically associate ocular inflammation during contact lens wear with serious complications such as microbial keratitis; however, more subtle mechanisms may be at play. This paper tests the notion that contact lens wear is intrinsically inflammatory by exploring whether uncomplicated contact lens wear meets the classical, clinical definition of inflammation - rubor (redness), calor (heat), tumor (swelling), dolor (pain) and functio laesa (loss of function) - as well as the contemporary, sub-clinical definition of inflammation (cellular and biochemical reactions)...
November 2, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/27800266/polymicrobial-infection-of-the-cornea-due-to-contact-lens-wear
#6
Selçuk Sızmaz, Sibel Bingöllü, Elif Erdem, Filiz Kibar, Soner Koltaş, Meltem Yağmur, Reha Ersöz
A 38-year-old male presented with pain and redness in his left eye. He had a history of wearing contact lenses. His ophthalmic examination revealed a large corneal ulcer with surrounding infiltrate. Cultures were isolated from the contact lenses, lens solutions, storage cases, and conjunctivae of both eyes and also corneal scrapings of the left eye. Fortified vancomycin and amikacin drops were started hourly. Culture results of conjunctivae of each eye and left cornea were positive for Pseudomonas aeruginosa; cultures from the contact lenses, lens solution and storage case of both eyes revealed Pseudomonas aeruginosa and Alcaligenes xylosoxidans...
April 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27793130/repertoire-of-free-living-protozoa-in-contact-lens-solutions
#7
Ibtissem Bouchoucha, Aurore Aziz, Louis Hoffart, Michel Drancourt
BACKGROUND: The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens. METHODS: Between 2009 and 2014, the contact lens solutions collected from patients presenting at our Ophthalmology Department for clinically suspected keratitis, were cultured on non-nutrient agar examined by microscope for the presence of free-living protozoa. All protozoa were identified by 18S rRNA gene sequencing...
October 29, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27787217/isolation-and-molecular-characterization-of-acanthamoeba-genotypes-isolated-from-soil-sources-of-public-and-recreational-areas-in-iran
#8
Seyed Ahmad Karamati, Maryam Niyyati, Jacob Lorenzo-Morales, Zohreh Lasjerdi
Pathogenic strains of Acanthamoeba are causative agents of a sight threating infection of the cornea known as Acanthamoeba keratitis. AK cases have been reported in Iran recently due to inappropriate usage of contact lens maintenance and most patients report a contact with contaminated sources such as dust, water or soil. Sixty soil samples were collected from public and recreational areas in the province of East Azerbaijan, Iran and checked for the presence of Acanthamoeba spp. Samples were cultured on non-nutrient agar plates seeded with heat killed Escherichia coli...
December 1, 2016: Acta Parasitologica
https://www.readbyqxmd.com/read/27771327/in-vivo-confocal-microscopy-of-corneal-nerves-in-health-and-disease
#9
Andrea Cruzat, Yureeda Qazi, Pedram Hamrah
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal physiology and disease. Enabling the dissection of corneal architecture at a cellular level, this technique offers fast and noninvasive in vivo imaging of the cornea with images comparable to that of ex vivo histochemical techniques. Corneal nerves bear substantial relevance to clinicians and scientists alike, given their pivotal roles in regulation of corneal sensation, maintenance of epithelial integrity, and proliferation and promotion of wound healing...
October 19, 2016: Ocular Surface
https://www.readbyqxmd.com/read/27768798/melimine-coated-antimicrobial-contact-lenses-reduce-microbial-keratitis-in-an-animal-model
#10
Debarun Dutta, Ajay K Vijay, Naresh Kumar, Mark D P Willcox
Purpose: To determine the ability of antimicrobial peptide melimine-coated contact lenses to reduce the incidence of microbial keratitis (MK) in a rabbit model of contact lens wear. Methods: In vitro antimicrobial activity of melimine-coated contact lenses was determined against Pseudomonas aeruginosa by viable count and a radiolabeled assay. The amount of lipopolysaccharide (LPS) associated with bacteria bound to melimine-coated and control lenses was determined...
October 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27755163/epidemiology-and-outcome-of-microbial-keratitis-private-university-versus-urban-public-hospital-care
#11
David T Truong, Minh-Thuy Bui, H Dwight Cavanagh
PURPOSE: To review the epidemiology, risk factors, microbiologic spectrum, and treatment of microbial keratitis during a 5-year period at an urban public hospital in comparison with an adjacent private university practice. METHODS: Retrospective chart review in the 5-year interval, 2009 through 2014. Primary outcome measures included patient age at presentation, best-corrected visual acuity (BCVA), risk factors, culture and sensitivities, treatment, and complication occurrence...
October 7, 2016: Eye & Contact Lens
https://www.readbyqxmd.com/read/27738866/the-comparison-of-antimicrobial-effectiveness-of-contact-lens-solutions
#12
Ali Kal, Mustafa Ilker Toker, Serpil Kaya
PURPOSE: The aim of this study was to compare the effects of widely used multipurpose contact lens solutions against Staphylococcus aureus and Pseudomonas aeruginosa, in addition to cystic and trophozoite forms of Acanthamoeba castellanii and A. polyphaga, that cause microbial keratitis. METHODS: Three multipurpose solutions were tested: SOLO-care, ReNu, and Opti-Free Express. The test solutions were challenged with P. aeruginosa (ATCC 27853) and S. aureus (ATCC 2913) based on the ISO stand-alone and regiment test procedure for disinfecting products, A...
October 13, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27721784/corneal-ring-infiltrates-caused-by-serratia-marcescens-in-a-patient-with-human-immunodeficiency-virus
#13
Winai Chaidaroon, Sumet Supalaset
PURPOSE: To describe corneal ring infiltrates caused by Serratia marcescens in a patient with human immunodeficiency virus (HIV-1) who wore contact lenses. METHODS: A case study of a patient with keratitis due to an infection caused by S. marcescens and exhibiting corneal ring infiltrates was reviewed for history, clinical manifestation, microscopic study, and management. RESULTS: A 29-year-old man who had a history of contact lens wear and HIV-1 infection was admitted to hospital because of blurred vision, redness, and corneal infiltrates in the shape of a ring in the left eye...
May 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/27670247/human-tear-fluid-reduces-culturability-of-contact-lens-associated-pseudomonas-aeruginosa-biofilms-but-induces-expression-of-the-virulence-associated-type-iii-secretion-system
#14
Yvonne T Wu, Connie Tam, Lucia S Zhu, David J Evans, Suzanne M J Fleiszig
PURPOSE: The type III secretion system (T3SS) is a significant virulence determinant for Pseudomonas aeruginosa. Using a rodent model, we found that contact lens (CL)-related corneal infections were associated with lens surface biofilms. Here, we studied the impact of human tear fluid on CL-associated biofilm growth and T3SS expression. METHODS: P. aeruginosa biofilms were formed on contact lenses for up to 7 days with or without human tear fluid, then exposed to tear fluid for 5 or 24 h...
September 23, 2016: Ocular Surface
https://www.readbyqxmd.com/read/27658596/isolation-and-genotyping-of-acanthamoeba-spp-as-neglected-parasites-in-north-of-iran
#15
Azar Shokri, Shahabeddin Sarvi, Ahmad Daryani, Mehdi Sharif
Acanthamoeba, a free-living amoeba, is widely distributed in the environment, water sources, soil, dust, and air. It can cause keratitis in contact lens wearers with poor hygiene and also fatal granulomatous amebic encephalitis (GAE) in immunocompromised hosts. The aim of this study was to gain some insights into the distribution and genotypes of the potentially pathogenic species of Acanthamoeba present in water sources in north of Iran. Total 43 Acanthamoeba species were isolated from 77 water samples taken from different water sources within the Mazandaran province in Northern Iran (Sari city and suburbs)...
August 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/27600042/the-development-of-drugs-against-acanthamoeba-infections
#16
Ruqaiyyah Siddiqui, Yousuf Aqeel, Naveed Ahmed Khan
For the past several decades, there has been little improvement in the morbidity and mortality associated with Acanthamoeba keratitis and Acanthamoeba encephalitis respectively. The discovery of a plethora of anti-Acanthamoebic compound(s) has not yielded effective marketed chemotherapeutics. The development of novel anti-Acanthamoebic chemotherapies of translational value and a lack of interest by the pharmaceutical industry has been disappointing. On the other hand, the market for contact lenses/contact lens disinfectants is a multibillion-dollar industry and has been successful and profitable...
September 6, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27576919/laboratory-diagnosis-of-acanthamoeba-keratitis-in-hungary
#17
Erika Orosz, Ágnes Farkas, István Kucsera
Acanthamoeba species are free-living amebae that can be found in almost every range of environments. Within this genus, numerous species are recognized as human pathogens, potentially causing Acanthamoeba keratitis (AK). AK is a corneal disease that is predominantly associated with contact lens use, the epidemiology of which is related to the specific genotype of Acanthamoeba. This study reports seven (7/16; 43.75%) positive cases. Detection of Acanthamoeba in corneal scrapings is based on cultivation and polymerase chain reaction (PCR) combined with the molecular taxonomic identification method...
September 2016: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/27560034/rare-case-of-polymicrobial-keratitis-with-balantidium-coli
#18
Manali Hazarika, Vijaya Pai H, Vinay Khanna, Harish Reddy, Kriti Tilak, Kiran Chawla
PURPOSE: To report a rare case of polymicrobial keratitis due to Balantidium coli and gram-negative bacteria, Pseudomonas aeruginosa and Klebsiella pneumoniae, in a soft contact lens (CL) wearer. METHODS: We report a case of CL-related keratitis due to B. coli, P. aeruginosa, and K. pneumoniae. RESULTS: The culture of the corneal scrapings, the CL cleaning solution, and the CL revealed the growth of a rare ciliated parasite, B. coli, along with gram-negative bacteria, namely, P...
August 24, 2016: Cornea
https://www.readbyqxmd.com/read/27545086/molecular-detection-and-genotyping-of-acanthamoeba-spp-among-stray-dogs-using-conjunctival-swab-sampling
#19
Mehmet Karakuş, Mehmet Aykur, Yusuf Özbel, Seray Töz, Hande Dağcı
Acanthamoeba is one of the most common free-living amoebas (FLA) that present in environment. In humans, Acanthamoeba can cause an infection of the eye termed Acanthamoeba keratitis, which mostly occurs in contact lens wearers. In the present study, we aimed to screen the presence of Acanthamoeba DNA in stray dogs using previously collected conjunctival swab samples in a hyper-endemic area for canine leishmaniasis. Totally, 184 dogs were included in the study and 27 of them (14.6%) were found positive for Acanthamoeba according to the 18s rRNA gene sequencing...
August 18, 2016: Acta Tropica
https://www.readbyqxmd.com/read/27541969/clinical-and-microbiological-profile-of-bacterial-microbial-keratitis-in-a-portuguese-tertiary-referral-center-where-are-we-in-2015
#20
Carla Sofia Ferreira, Luis Figueira, Nuno Moreira-Gonçalves, Raúl Moreira, Luis Torrão, Fernando Falcão-Reis
OBJECTIVES: To study the microbial profile, antibiotic susceptibility pattern, risk factors, therapeutic trends, and clinical outcomes for microbial keratitis (MK) in a tertiary health care center. METHODS: All cases with suspected bacterial keratitis that were followed at consultation from September 2007 to August 2015 were included. Microbial cultures were obtained and patients were managed following an internal protocol. RESULTS: Two hundred thirty-five patients were included, with a mean age of 50...
July 12, 2016: Eye & Contact Lens
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