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Contact lens keratitis

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https://www.readbyqxmd.com/read/28520596/fungal-keratitis-associated-with-airborne-organic-debris-and-soft-contacts-lenses-case-reports-and-review-of-the-literature
#1
Michael J Hodkin, Ryan C Gustus
OBJECTIVES: To report two cases of fungal keratitis in soft contact lens wearers who were exposed to environmental mold. METHODS: Case reports, with review of the relevant literature. RESULTS: Two otherwise healthy middle-aged women who were soft contact lens wearers developed fungal keratitis about 1 week after heavy exposure to environmental mold. Culture results showed Aspergillus from one patient and the unusual combination of Trichoderma and Penicillium from the other...
May 16, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28514244/the-safety-of-soft-contact-lenses-in-children
#2
Mark A Bullimore
PURPOSE: There is increasing interest in fitting children with soft contact lenses. This review collates data from a range of studies to estimate the incidence of complications, specifically corneal infiltrative events and microbial keratitis, in patients under the age of 18 years. METHODS: Peer-review papers were identified using PubMed and the Web of Science. A broad range of studies are summarized including large-scale epidemiological studies of contact lens-related complications, hospital-based case series, long- and short-term prospective studies, and multicenter retrospective studies...
May 16, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28489721/tear-cytokine-levels-in-contact-lens-wearers-with-acanthamoeba-keratitis
#3
Nicole Carnt, Vicente M Montanez, Grazyna Galatowicz, Neyme Veli, Virginia Calder
PURPOSE: To determine differences in key tear film cytokines between mild and severe cases of acanthamoeba keratitis (AK) and control contact lens (CL) wearers. METHODS: This was a prospective study of CL wearers with AK attending Moorfields Eye Hospital and control CL wearers from the Institute of Optometry, London. Basal tear specimens were collected by 10-μL capillary tubes (BLAUBRAND intraMark, Wertheim, Germany), and tear protein levels were measured with a multiplex magnetic bead array (Luminex 100; Luminex Corporation, Austin, TX) for cytokines interleukin (IL)-1β, IL-6, IL-8, IL-10, IL-17A, IL-17E, IL-17F, IL-22, and interferon gamma and with enzyme-linked immunosorbent assay (Abcam, Cambridge, United Kingdom) for CXCL2...
May 9, 2017: Cornea
https://www.readbyqxmd.com/read/28486311/free-living-amoebae-keratitis
#4
Antonio Pinna, Tiziana Porcu, Francesco Boscia, Antonella Cano, Giuseppe Erre, Antonella Mattana
PURPOSE: To describe the diagnostic and clinical features and treatment results in 43 consecutive patients with microbiologically proven free-living amoebae (FLA) keratitis. METHODS: In this hospital-based, prospective case series, corneal scrapings from 43 patients with presumed amoebic keratitis were plated on nonnutrient agar. Amoebic isolates were identified morphologically and by the polymerase chain reaction. All patients with culture-proven FLA keratitis were treated with polyhexamethylene biguanide (PHMB) 0...
May 8, 2017: Cornea
https://www.readbyqxmd.com/read/28450791/a-case-report-of-central-toxic-keratopathy-in-a-patient-post-transprk-followed-by-corneal-collagen-cross-linking
#5
Nicholas Davey, Ioannis M Aslanides, Vasilis Selimis
PURPOSE: The purpose of this article is to report a case of central toxic keratopathy in a patient post transepithelial photorefractive keratectomy (TransPRK), followed immediately by corneal collagen cross-linking. METHODS: This article describes the case of a 26-year-old male after bilateral aberration-free, TransPRK laser (Schwind Amaris 750S). The procedure was performed for compound myopic astigmatism in November 2015, followed immediately by accelerated corneal collagen cross-linking for early keratoconus...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28410356/water-exposure-is-a-common-risk-behavior-among-soft-and-gas-permeable-contact-lens-wearers
#6
Aaron B Zimmerman, Kathryn Richdale, Gladys Lynn Mitchell, Beth T Kinoshita, Dawn Y Lam, Heidi Wagner, Luigina Sorbara, Robin L Chalmers, Sarah A Collier, Jennifer R Cope, Maya M Rao, Michael J Beach, Jonathan S Yoder
PURPOSE: To understand soft contact lens (SCL) and gas-permeable (GP) lens wearers' behaviors and knowledge regarding exposure of lenses to water. METHODS: The Contact Lens Risk Survey (CLRS) and health behavior questions were completed online by a convenience sample of 1056 SCL and 85 GP lens wearers aged 20 to 76 years. Participants were asked about exposing their lenses to water and their understanding of risks associated with these behaviors. Chi-square analyses examined relationships between patient behaviors and perceptions...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28380096/visual-rehabilitation-using-mini-scleral-contact-lenses-after-penetrating-keratoplasty
#7
Guilherme Andrade do Nascimento Rocha, Patrícia Oliveira Braga Miziara, Ana Clara Vieira de Castro, Arthur Andrade do Nascimento Rocha
Purpose: To report the visual rehabilitation outcomes and complications of patients fitted with mini-scleral rigid gas-permeable (RGP) contact lenses (mini-SCLs) after penetrating keratoplasty. Methods: We retrospectively reviewed 27 eyes (21 patients) that were fitted with mini-SCLs between October 2013 and December 2014. We analyzed demographic data, previous corneal disorders, visual outcomes, interval from keratoplasty to contact lens fitting, topographic and specular microscope data, fitted contact lens parameters, and complications...
January 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28376553/fungal-keratitis-a-six-year-review-at-a-tertiary-referral-centre
#8
K C Iselin, P B Baenninger, A Schmittinger-Zirm, M A Thiel, C Kaufmann
Background This review reports the epidemiology, laboratory results, treatment regimens and costs of fungal keratitis at a tertiary referral center in Lucerne, Switzerland. Patients and Methods Culture-proven fungal infections between January 2010 and December 2015 were reviewed retrospectively. Results Seventeen patients with a mean age of 52 years were identified. Contact lens wear was the most important risk factor (n = 11) (65 % of all cases), with filamentous fungi being identified as the most common fungus type (n = 10) (91 % of all cases of contact lens-associated fungal keratitis)...
April 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28359825/bilateral-simultaneous-infective-keratitis
#9
Lai Hiu On Annie, Manotosh Ray
AIM: To analyze the demographics, risk factors, clinical and microbiological characteristics of cases of bilateral simultaneous infective keratitis. METHODS: In this retrospective case series, patients with clinical evidence of bilateral simultaneous infective keratitis were identified from January 1, 2011 to August 31, 2016. Demographics, risk factors, clinical and microbiological characteristics, and treatment outcomes were analyzed. RESULTS: Five patients (ten eyes) with bilateral simultaneous infective keratitis were identified...
March 27, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28350622/keratitis-due-to-achromobacter-xylosoxidans-in-a-contact-lens-user
#10
Cristina Almenara Michelena, María Ángeles Del Buey, Francisco Javier Ascaso, Jose Ángel Cristóbal
OBJECTIVES: Ocular infections due to Achromobacter xylosoxidans are extremely uncommon; their diagnosis is a challenge and the optimal treatment remains controversial. We present a case of A. xylosoxidans in a contact lens user and a review of the literature to facilitate diagnostic suspicion and empirical therapeutic management. METHODS: Review of the literature in PubMed and MEDLINE. We also document a case diagnosed in our department in January 2016. SETTING: Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain...
March 27, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28336675/evolving-risk-factors-and-antibiotic-sensitivity-patterns-for-microbial-keratitis-at-a-large-county-hospital
#11
Haoxing Jin, Walter T Parker, Nathan W Law, Cameron L Clarke, Jordan D Gisseman, Stephen C Pflugfelder, Li Wang, Zaina N Al-Mohtaseb
Purpose: To identify the risk factors, causative organisms, antimicrobial susceptibility and outcomes of microbial keratitis in a large county hospital in Houston, Texas. Design: Case series. METHODS: Setting: A large county hospital in Houston, Texas. Study Population: Patients with known diagnosis of microbial keratitis from January 2011 to May 2015. Observation Procedure: Retrospective chart review. Main Outcomes: Epidemiology, risk factors, outcomes and antibiotic susceptibility of microbial keratitis...
March 23, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28325674/-risk-factors-for-contact-lens-related-microbial-keratitis-a-multicenter-case-control-study
#12
P H Becmeur, F Abry, T Bourcier, N Meyer, A Sauer
PURPOSE: Currently, the most feared complication by ophthalmologists of contact lens (CL) wear is microbial keratitis (MK), even though its incidence remains low. It is also a significant financial burden for society. This study aimed to identify the risk factors for CL-related MK especially with regard to hygiene and pattern of use, in a large, prospective, multicenter, case-control study. METHODS: A multicenter retrospective case-control study was designed. The CL-related MK subpopulation (case) was compared with healthy CL wearers (control) using a 52-item anonymous questionnaire designed to determine subject demographics, lens wear history, lens type and disinfection solution, fitting, patient education, hygiene and maintenance of contact lenses, and patient history...
March 18, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28317680/risk-for-microbial-keratitis-comparative-metaanalysis-of-contact-lens-wearers-and-post-laser-in-situ-keratomileusis-patients
#13
Jordan Masters, Mehmet Kocak, Aaron Waite
PURPOSE: To compare the risk for microbial keratitis in contact lens wearers stratified by wear schedule with the risk after laser in situ keratomileusis (LASIK). SETTING: Hamilton Eye Institute and Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA. DESIGN: Comparative metaanalysis and literature review. METHODS: An extensive literature search was performed in the PubMed database between December 2014 and July 2015...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28298316/paediatric-infectious-keratitis-a-case-series-of-107-children-presenting-to-a-tertiary-referral-centre
#14
Julia Dutra Rossetto, Kara M Cavuoto, Carla J Osigian, Ta Chen Peter Chang, Darlene Miller, Hilda Capo, Oriel Spierer
BACKGROUND/AIMS: Corneal ulcers can result in severe visual impairment in children. The recent trends of paediatric microbial ulcerative keratitis in the USA are unknown. The purpose of this study is to report the risk factors, microbiological profile and treatment outcomes of paediatric microbial keratitis in South Florida. METHODS: A university-based tertiary eye care centre retrospective case series between 1992 and 2015. Medical records of 107 paediatric patients (age <18 years) with the diagnosis of microbial ulcerative keratitis were analysed...
March 15, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28241309/a-rabbit-model-of-acanthamoeba-keratitis-use-of-infected-soft-contact-lenses-after-corneal-epithelium-debridement-with-a-diamond-burr
#15
Ángel Ortillés, Pilar Goñi, Encarnación Rubio, Marta Sierra, Ekaterina Gámez, María T Fernández, María Benito, José Á Cristóbal, Begoña Calvo
Purpose: To develop a rabbit model of Acanthamoeba keratitis (AK) as the best method to reproduce the natural course of this disease. Methods: To induce AK, infected contact lenses (1000 amoebae/mm2, 90% trophozoites) were placed over the previously debrided corneal surface, in combination with a temporary tarsorrhaphy. Environmental and clinical strains of Acanthamoeba spp. (genotype T4) were used. Three groups (1L, n = 32; 2L-21d, n = 5; 2L-3d, n = 23) were established according to the number of contact lenses used (1L, 1 lens; 2L-21d and 2L-3d, 2 lenses) and the placement day of these (1L, day 1; 2L-21d, days 1 and 21; 2L-3d, days 1 and 3)...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28223875/toxic-keratitis-after-use-of-wrongly-labeled-non-ophthalmic-medication
#16
Mohammad A Al-Amry, Nada Al-Abdan, Saleh A Al-Othaimeen
We present a 24-year-old female with trauma to her right eye. The patient was prescribed topical Tobramicin-dexamethasone eye drops but the pharmacy dispensed diclofenac diethyl amine ointment. The patient presented to the emergency room with lid edema, conjunctival injection and a corneal epithelial defect and toxic keratitis. The patient was successfully managed with copious irrigation, bandage contact lens and topical antibiotic therapy.
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28178141/a-non-surgical-approach-to-the-management-of-exposure-keratitis-due-to-facial-palsy-by-using-mini-scleral-lenses
#17
Victor Zaki
RATIONALE: This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy. PATIENT CONCERNS: Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. If left untreated, it leads to permanent damage to the cornea and loss of good functional vision. Mini-scleral lens keep the cornea covered by saline solution all wearing hours...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28151861/shifting-trends-in-microbial-keratitis-following-penetrating-keratoplasty-in-taiwan
#18
Hung-Chi Chen, Chia-Yi Lee, Hung-Yu Lin, David Hui-Kang Ma, Phil Yeong-Fong Chen, Ching-Hsi Hsiao, Hsin-Chiung Lin, Lung-Kun Yeh, Hsin-Yuan Tan
To investigate the clinical and microbiological profiles from microbial keratitis following penetrating keratoplasty (PKP) in a tertiary referral center in Taiwan, the medical records of 648 consecutive patients (648 eyes) undergoing PKP between January 2003 and December 2007 were retrospectively reviewed. Patients who subsequently sustained microbial keratitis were enrolled and analyzed for potential risk factors, clinical manifestations, microbiological profiles, complications, graft survival, and final visual outcome...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28131677/a-randomized-clinical-trial-to-evaluate-the-usefulness-of-amniotic-membrane-transplantation-in-bacterial-keratitis-healing
#19
Seyed Ali Tabatabaei, Mohammad Soleimani, Mahmoud Jabbarvand Behrouz, Ali Torkashvand, Pasha Anvari, Mehdi Yaseri
PURPOSE: To determine whether early amniotic membrane transplantation improves the outcomes among patients with bacterial keratitis. PATIENTS AND METHODS: In this prospective randomized clinical trial 49 eyes from 49 patients with bacterial keratitis received routine antibiotic therapy followed by double-layer amniotic membrane transplantation during 2-5 days after start up of the medications and the second group of 50 eyes from 50 patients only received routine antibacterial therapy...
January 25, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28124962/-investigation-of-the-in-vitro-effects-of-melissa-officinalis-l-mentha-x-piperita-l-and-ocimum-basilicum-l-lamiaceae-essential-oils-on-the-cysts-and-trophozoites-of-acanthamoeba-castellani
#20
Ceren Ergüden, Soykan Özkoç, Bintuğ Öztürk, Songül Bayram Delibaş
Acanthamoeba species are free living amoeba found widely all over the world. They are responsible for Acanthamoeba keratitis (AK), an infection which is especially seen in contact lens users and after minor corneal traumas, that may lead blindness. At present, antifungals and antiseptics are used for the treatment of AK cases, however, some problems such as long treatment periods and the occurrence of side effects, resistance of cyst forms against drugs, emphasize the need for new drugs. There are some published studies that pointed out the effectiveness of plant extracts and essential oils on Acanthamoeba spp...
October 2016: Mikrobiyoloji Bülteni
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