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https://www.readbyqxmd.com/read/29427878/traffic-related-air-pollution-and-development-and-persistence-of-asthma-and-low-lung-function
#1
Gayan Bowatte, Caroline J Lodge, Luke D Knibbs, Bircan Erbas, Jennifer L Perret, Bin Jalaludin, Geoffrey G Morgan, Dinh S Bui, Graham G Giles, Garun S Hamilton, Richard Wood-Baker, Paul Thomas, Bruce R Thompson, Melanie C Matheson, Michael J Abramson, E Haydn Walters, Shyamali C Dharmage
BACKGROUND AND AIMS: Traffic Related Air Pollution (TRAP) exposure is known to exacerbate existing respiratory diseases. We investigated longer term effects of TRAP exposure for individuals with or without existing asthma, and with or without lower lung function. METHODS: Associations between TRAP exposure and asthma (n = 689) and lung function (n = 599) were investigated in the prospective Tasmanian Longitudinal Health Study (TAHS). TRAP exposure at age 45 years was measured using two methods based on residential address: mean annual NO2 exposure; and distance to nearest major road...
February 7, 2018: Environment International
https://www.readbyqxmd.com/read/29405766/urinary-bisphenol-a-levels-in-turkish-girls-with-premature-thelarche
#2
E Durmaz, A Asci, P Erkekoglu, A Balcı, I Bircan, B Koçer-Gumusel
There is a growing concern over the timing of pubertal breast development and its possible association with exposure to endocrine disrupting chemicals (EDCs), such as bisphenol A (BPA). BPA is abundantly used to harden plastics. The aim of this study was to investigate the relation between premature thelarche (PT) and BPA by comparing the urinary BPA levels of PT girls with those of healthy subjects. Twenty-five newly diagnosed nonobese PT subjects (aged 4-8 years) who were admitted to the Pediatric Endocrinology Department at Akdeniz University were recruited...
January 1, 2018: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/29405729/the-effects-of-resveratrol-on-hepatic-oxidative-stress-in-metabolic-syndrome-model-induced-by-high-fructose-diet
#3
C Yilmaz Demirtas, F S Bircan, O T Pasaoglu, N Turkozkan
BACKGROUND: The purpose of this study was to evaluate probable protective effects of resveratrol treatment on hepatic oxidative events in a rat model of metabolic syndrome (MetS). METHODS: Thirty-two male adult rats were randomly divided into 4 groups: control, fructose, resveratrol, and fructose plus resveratrol. To induce MetS, fructose solution (20 % in drinking water) was used. Resveratrol (10 mg/kg/day) was given by oral gavage. All treatments were given for 8 weeks...
2018: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29353264/response-to-growth-hormone-treatment-in-very-young-patients-with-growth-hormone-deficiencies-and-mini-puberty
#4
Semra Çetinkaya, Şükran Poyrazoğlu, Firdevs Baş, Oya Ercan, Metin Yıldız, Erdal Adal, Abdullah Bereket, Saygın Abalı, Zehra Aycan, Şenay Savaş Erdeve, Merih Berberoğlu, Zeynep Şıklar, Meltem Tayfun, Şükran Darcan, Eda Mengen, İffet Bircan, Filiz Mine Çizmecioğlu Jones, Enver Şimşek, Esra Deniz Papatya, Mehmet Nuri Özbek, Semih Bolu, Ayhan Abacı, Muammer Büyükinan, Feyza Darendeliler
BACKGROUND: The aim of the study was to assess the response to growth hormone (GH) treatment in very young patients with GH deficiency (GHD) through a national, multi-center study. Possible factors affecting growth response were assessed (especially mini-puberty). METHODS: Medical reports of GHD patients in whom treatment was initiated between 0 and 3 years of age were retrospectively evaluated. RESULTS: The cohort numbered 67. The diagnosis age was 12...
January 20, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29331087/outdoor-pollen-is-a-trigger-of-child-and-adolescent-asthma-ed-presentations-a-systematic-review-and-meta-analysis
#5
REVIEW
Bircan Erbas, Mitra Jazayeri, Katrina A Lambert, Constance H Katelaris, Luke A Prendergast, Rachel Tham, M Jeannette Parrodi, Janet Davies, Ed Newbigin, Michael J Abramson, Shyamali C Dharmage
BACKGROUND: In the context of increased asthma exacerbations associated with climatic changes such as thunderstorm asthma, interest in establishing the link between pollen exposure and asthma hospital admissions has intensified. Here, we systematically reviewed and performed a meta-analysis of studies on pollen and ED attendance. METHODS: A search for studies with appropriate search strategy in Medline, Embase, Web of Science and CINAHL was conducted. Each study was assessed for quality and risk of bias...
January 13, 2018: Allergy
https://www.readbyqxmd.com/read/29295917/graphene-based-bimorphs-for-micron-sized-autonomous-origami-machines
#6
Marc Z Miskin, Kyle J Dorsey, Baris Bircan, Yimo Han, David A Muller, Paul L McEuen, Itai Cohen
Origami-inspired fabrication presents an attractive platform for miniaturizing machines: thinner layers of folding material lead to smaller devices, provided that key functional aspects, such as conductivity, stiffness, and flexibility, are persevered. Here, we show origami fabrication at its ultimate limit by using 2D atomic membranes as a folding material. As a prototype, we bond graphene sheets to nanometer-thick layers of glass to make ultrathin bimorph actuators that bend to micrometer radii of curvature in response to small strain differentials...
January 2, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29248387/the-prevalence-of-food-sensitization-appears-not-to-have-changed-between-2-melbourne-cohorts-of-high-risk-infants-recruited-15-years-apart
#7
Rachel L Peters, Jennifer J Koplin, Katrina J Allen, Adrian J Lowe, Caroline J Lodge, Mimi L K Tang, Melissa Wake, Anne-Louise Ponsonby, Bircan Erbas, Michael J Abramson, David Hill, Lyle C Gurrin, Shyamali C Dharmage
BACKGROUND: Although food allergy has probably risen over recent decades, recent reports suggest that the prevalence of food sensitization in the general population has not changed. However, this has not been analyzed in infants at high risk of food allergy. OBJECTIVE: The objective of this study was to compare the prevalence of food sensitization in high-risk infants from 2 cohorts recruited 15 years apart in the same region. METHODS: This study includes 620 high-risk infants with a family history of allergy (Melbourne Atopy Cohort Study [MACS]) born 1990-1994, and a subgroup of high-risk infants from the population-based HealthNuts study (n = 3,661/5,276), born 2006-2010...
December 13, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29074540/traffic-related-air-pollution-exposure-over-a-5-year-period-is-associated-with-increased-risk-of-asthma-and-poor-lung-function-in-middle-age
#8
Gayan Bowatte, Bircan Erbas, Caroline J Lodge, Luke D Knibbs, Lyle C Gurrin, Guy B Marks, Paul S Thomas, David P Johns, Graham G Giles, Jennie Hui, Martine Dennekamp, Jennifer L Perret, Michael J Abramson, E Haydn Walters, Melanie C Matheson, Shyamali C Dharmage
Current evidence concerning the impact of exposure to traffic-related air pollution (TRAP) on adult respiratory morbidity mainly comes from cross-sectional studies. We sought to establish more robust measures of this association and potential gene-environment interactions using longitudinal data from an established cohort study.Associations between measures of TRAP (nitrogen dioxide (NO2) and distance to major roads) and wheeze, asthma prevalence and lung function were investigated in participants of the Tasmanian Longitudinal Health Study at 45- and 50-year follow-ups...
October 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29020463/the-role-of-human-rhinovirus-hrv-species-on-asthma-exacerbation-severity-in-children-and-adolescents
#9
Katrina A Lambert, Luke A Prendergast, Shyamali C Dharmage, Mimi Tang, Molly O'Sullivan, Thomas Tran, Julian Druce, Philip Bardin, Michael J Abramson, Bircan Erbas
OBJECTIVE: It is recognized that human rhinovirus (HRV) infection is an important factor in asthma exacerbations requiring hospitalization in children. However, previous studies have disagreed on the differential impact of various HRV species. We sought to assess the impact of HRV species on the severity of asthma exacerbations in children and adolescents. We also examined whether the effect of HRV species on severity was modified by age and gender. METHODS: Virus strain was determined for 113 children with HRV detectable at the time of admission for asthma exacerbation...
October 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28899934/bronchial-hyperresponsiveness-and-obesity-in-middle-age-insights-from-an-australian-cohort
#10
John A Burgess, Melanie C Matheson, Fei Diao, David P Johns, Bircan Erbas, Adrian J Lowe, Lyle C Gurrin, Caroline J Lodge, Paul S Thomas, Stephen Morrison, Bruce R Thompson, Iain Feather, Jennifer L Perret, Michael J Abramson, Graham G Giles, John L Hopper, Shyamali C Dharmage, Eugene H Walters
The association between obesity and bronchial hyperresponsiveness (BHR) is incompletely characterised. Using the 2006 follow-up of the Tasmanian Longitudinal Health Study, we measured the association between obesity and BHR and whether it was mediated by small airway closure or modified by asthma and sex of the patient.A methacholine challenge measured BHR. Multivariable logistic regression measured associations between body mass index (BMI) and BHR, adjusting for sex, asthma, smoking, corticosteroid use, family history and lung function...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28890656/effects-of-teaching-health-care-workers-on-diagnosis-and-treatment-of-pesticide-poisonings-in-uganda
#11
REVIEW
Claudia Sibani, Kristian Kjaer Jessen, Bircan Tekin, Victoria Nabankema, Erik Jørs
BACKGROUND: Acute pesticide poisoning in developing countries is a considerable problem, requiring diagnosis and treatment. This study describes how training of health care workers in Uganda affects their ability to diagnose and manage acute pesticide poisoning. METHOD: A postintervention cross-sectional study was conducted using a standardized questionnaire. A total of 326 health care workers in Uganda were interviewed on knowledge and handling of acute pesticide poisoning...
2017: Environmental Health Insights
https://www.readbyqxmd.com/read/28886703/factors-associated-with-foot-ulceration-and-amputation-in-adults-on-dialysis-a-cross-sectional-observational-study
#12
Michelle R Kaminski, Anita Raspovic, Lawrence P McMahon, Katrina A Lambert, Bircan Erbas, Peter F Mount, Peter G Kerr, Karl B Landorf
BACKGROUND: Adults on dialysis are at increased risk of foot ulceration, which commonly precedes more serious lower limb complications, including amputation. Limited data exist regarding the prevalence and factors associated with foot disease in this population. Hence, this study set out to investigate factors associated with foot ulceration and amputation in a dialysis cohort. METHODS: This study presents a cross-sectional analysis of baseline data from a multi-center prospective cohort study...
September 8, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28803594/does-adherence-to-the-mediterranean-dietary-pattern-reduce-asthma-symptoms-in-children-a-systematic-review-of-observational-studies
#13
Maria M Papamichael, Catherine Itsiopoulos, Nugroho H Susanto, Bircan Erbas
OBJECTIVE: The purpose of the present systematic review was to synthesize evidence from the literature to assess efficacy of the Mediterranean dietary pattern in childhood asthma. Design/Setting A systematic search of six databases, three clinical trial registries and hand-search of peer-reviewed articles was conducted up to 29 October 2016. Inclusion criteria included exposure to a Mediterranean dietary pattern, measurement of asthma symptoms and study population of children aged <18 years...
October 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28757048/a-long-term-multicenter-study-entecavir-versus-tenofovir-in-treatment-of-nucleos-t-ide-analogue-naive-chronic-hepatitis-b-patients
#14
Bircan Kayaaslan, Esragul Akinci, Alpay Ari, Zeliha Kocak Tufan, Saygın Nayman Alpat, Ozgur Gunal, Selma Tosun, Rahmet Guner, Fehmi Tabak
BACKGROUND: Entecavir (ETV) and tenofovir disoproxil fumarat (TDF) are the two first-line therapies recommended in the treatment of chronic hepatitis B because of having potent antiviral effect and high genetic barriers against resistance. We aimed to compare efficacy of these drugs and to evaluate predictors of viral suppression. METHODS: This multicenter retrospective study was conducted in nucleos(t)ide analogue-naive chronic hepatitis B (CHB) patients from different 6 centers...
July 27, 2017: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/28695900/reliability-validity-and-sensitivity-to-change-of-neurogenic-bowel-dysfunction-score-in-patients-with-spinal-cord-injury
#15
D Erdem, D Hava, P Keskinoğlu, Ç Bircan, Ö Peker, K Krogh, S Gülbahar
STUDY DESIGN: Psychometrics study. OBJECTIVES: The aim of this study is to investigate the validity, reliability and sensitivity to change of neurogenic bowel dysfunction (NBD) score. SETTING: Dokuz Eylül University Faculty of Medicine, Turkey. METHODS: The study included 42 patients with spinal cord injury (SCI). The reliability of NBD score was assessed by test-retest reliability and internal consistency. Cronbach's alpha coefficient was calculated to determine internal consistency...
July 11, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28689102/monthly-methylprednisolone-in-combination-with-interferon-beta-or-glatiramer-acetate-for-relapsing-remitting-multiple-sclerosis-a-multicentre-single-blind-prospective-trial
#16
Serkan Ozakbas, Bilge Piri Cinar, Gorkem Kosehasanoğullari, Turhan Kahraman, Didem Oz, Behice Bircan Kursun
OBJECTIVES: Multiple sclerosis is usually clinically characterized by repeated subacute relapses followed by remissions. Corticosteroids are used for relapses, and this treatment has been shown to increase the speed of recovery from these. We aimed to evaluate the efficacy and safety of pulsed methylprednisolone given every month as an add-on therapy to interferon beta or glatiramer acetate in patients with relapsing-remitting multiple sclerosis. PATIENTS AND METHODS: This was a multi-center, examiner-blinded, prospective study...
September 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28575785/effect-of-season-of-birth-on-cord-blood-ige-and-ige-at-birth-a-systematic-review-and-meta-analysis
#17
REVIEW
Nugroho Harry Susanto, Don Vicendese, Agus Salim, Adrian J Lowe, Shyamali C Dharmage, Rachel Tham, Caroline Lodge, Frances Garden, Katie Allen, Cecilie Svanes, Joachim Heinrich, Michael J Abramson, Bircan Erbas
BACKGROUND: Elevated cord blood IgE is important on the pathway to allergic disease. The association between season of birth and infant cord blood IgE is not well-established. Study findings differ on which birth season is associated with higher cord blood IgE risk and its magnitude. We conducted a systematic review and meta-analysis of studies on season of birth and cord blood IgE. METHODS: We searched Medline, Web of Science, Scopus and ProQuest Health databases, and reviewed reference lists of articles that met the inclusion criteria...
August 2017: Environmental Research
https://www.readbyqxmd.com/read/28332960/evaluation-of-transplanted-kidneys-and-comparison-with-healthy-volunteers-and-kidney-donors-with-diffusion-weighted-magnetic-resonance-imaging-initial-experience
#18
Ümit Özçelik, Halime Çevik, Hüseyin Yüce Bircan, Feza Yarbuğ Karakayalı, İclal Işıklar, Mehmet Haberal
OBJECTIVES: The aim of this study was to evaluate the feasibility of diffusion-weighted magnetic resonance, by comparing imaging in renal allograft recipients for functional assessment of kidney transplants versus imaging of these features in healthy volunteers and kidney donors with native kidneys. MATERIALS AND METHODS: Seventy renal transplant recipients (group A) with stable graft function at postoperative month 1, 40 healthy volunteers (group B), and 40 kidney donors (group C) underwent diffusion-weighted magnetic resonance imaging...
March 22, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28315571/the-relationship-of-micronucleus-frequency-and-nuclear-division-index-with-coronary-artery-disease-syntax-and-gensini-scores
#19
Emrah İpek, Emrah Ermiş, Handan Uysal, Halit Kızılet, Selami Demirelli, Erkan Yıldırım, Sedat Ünver, Bircan Demir, Nergiz Kızılet
OBJECTIVE: We aimed to evaluate the relationship of micronucleus (MN) frequency and nuclear division index (NDI) with SYNTAX and Gensini scores and thrombolysis in myocardial infarction (TIMI) frame counts of coronary arteries in patients undergoing coronary angiography. METHODS: In a single-center prospective observational study, a total of 63 individuals, 48 consecutive patients with coronary artery disease (CAD) and 15 healthy people were included. Before coronary angiography (exposure to X-ray), blood samples were collected for lymphocyte cultures, MN and NDI measurements...
June 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28301056/age-at-onset-and-persistence-of-eczema-are-related-to-subsequent-risk-of-asthma-and-hay-fever-from-birth-to-18%C3%A2-years-of-age
#20
Adrian J Lowe, Bianca Angelica, John Su, Caroline J Lodge, David J Hill, Bircan Erbas, Catherine M Bennett, Lyle C Gurrin, Christine Axelrad, Michael J Abramson, Katrina J Allen, Shyamali C Dharmage
BACKGROUND: Few studies have simultaneously addressed the importance of age of onset and persistence of eczema for the subsequent development of asthma and hay fever, particularly into early adulthood. METHODS: A high-risk birth cohort was recruited comprising 620 infants, who were then followed up frequently until 2 years of age, annually from age 3 to 7, then at 12 and 18 years, to document any episodes of eczema, current asthma, and hay fever. The generalized estimation equation technique was used to examine asthma and hay fever outcomes at 6 (n = 325), 12 (n = 248) and 18 (n = 240) years, when there was consistency of associations across the follow-ups...
June 2017: Pediatric Allergy and Immunology
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