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Strategic adherence

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https://www.readbyqxmd.com/read/28702176/monitoring-and-evaluating-the-adherence-to-a-complementary-food-supplement-ying-yang-bao-among-young-children-in-rural-qinghai-china-a-mixed-methods-evaluation-study
#1
Qiong Wu, Yanfeng Zhang, Suying Chang, Wei Wang, Michelle Helena van Velthoven, Huijun Han, Min Xing, Li Chen, Xiaozhen Du, Robert W Scherpbier
BACKGROUND: Large investments are currently made in community-based complementary food supplement (Ying Yang Bao, YYB) programs to improve nutrition of young children in rural areas in China. However, there is a lack of knowledge about the experience and challenges of implementing YYB programs in China. We aimed to: 1) monitor distribution of YYB; 2) assess children's adherence to and acceptability of YYB; and 3) evaluate community-based strategies to improve the program. METHODS: This mixed methods evaluation study combined data from surveys and focus groups that took place during a controlled interventional evaluation trial...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28684081/self-reported-adherence-to-diet-and-preferences-towards-type-of-meal-plan-in-patient-with-type-2-diabetes-mellitus-a-cross-sectional-study
#2
V Ponzo, R Rosato, E Tarsia, I Goitre, F De Michieli, M Fadda, T Monge, A Pezzana, F Broglio, S Bo
BACKGROUND AND AIMS: Few studies have evaluated the attitudes of patients with type 2 diabetes mellitus (T2DM) towards the given dietary plans. In this study, we aimed to evaluate: i) the self-reported adherence of T2DM patients to the prescribed diets; ii) the use of other types of diet schemes; iii) the patients' preferences towards the type of meal plans. METHODS AND RESULTS: A 16 multiple-choice items questionnaire was administered to 500 T2DM patients; 71.2% (356/500) of them had the perception of having received a dietary plan; only 163/356 declared to be fully adherent...
June 1, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28673254/a-cross-sectional-study-to-evaluate-second-line-virological-failure-and-elevated-bilirubin-as-a-surrogate-for-adherence-to-atazanavir-ritonavir-in-two-urban-hiv-clinics-in-lilongwe-malawi
#3
Dennis Miyoge Ongubo, Robertino Lim, Hannock Tweya, Christopher Chikhosi Stanley, Petros Tembo, Richard Broadhurst, Salem Gugsa, McNeil Ngongondo, Colin Speight, Tom Heller, Sam Phiri, Mina C Hosseinipour
BACKGROUND: Malawi's national antiretroviral therapy program provides atazanavir/ritonavir-based second line regimens which cause concentration-dependent rise in indirect bilirubin. We sought to determine if elevated bilirubin, as a surrogate of atazanavir/ritonavir adherence, can aid in the evaluation of second line virological failure in Malawi. METHODS: We conducted a cross-sectional study of HIV-infected patients ≥15 years who were on boosted protease inhibitor-based second line antiretroviral therapy for at least 6 months in two urban HIV clinics in Lilongwe, Malawi...
July 3, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28671699/developing-new-platform-chemicals-what-is-required-for-a-new-bio-based-molecule-to-become-a-platform-chemical-in-the-bioeconomy
#4
José-Vitor Bomtempo, Flavia Chaves Alves, Fabio de Almeida Oroski
This paper proposes a framework with six dimensions that can be useful for evaluating the potential and the current stage of a bio-based platform chemical. The framework considers the technological and strategic challenges to be fulfilled by a company that intends to lead a platform based on a bio-based chemical. A platform chemical should be an intermediate molecule, with a structure able to generate a number of derivatives, that is produced at a competitive cost, capable of allowing exploitation of the scale and scope economies, and inserted within a complete innovation ecosystem that is able to create value with governance mechanisms that are capable of allowing coordination of the innovation process and facilitation of the value capture by the focal company leading the platform, in our case the producer of the platform molecule...
July 3, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28634619/implementation-of-li-rads-into-a-radiological-practice
#5
REVIEW
Stefan T Siedlikowski, Ania Z Kielar, Eleanor L Ormsby, Bijan Bijan, Christopher Kagay
Since its introduction in 2011, Liver Imaging Reporting and Data System (LI-RADS) has become an increasingly utilized method for radiologists to categorize lesions for hepatocellular carcinoma (HCC) in patients at risk (American College of Radiology, www.acr.org/quality-safety/resources/lirads 2016). This overview article presents insight into methods of incorporating LI-RADS into an existing clinical practice, highlighting concrete ways to establish this system as a mainstay in any radiologist's evidence-based armamentarium...
June 20, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28622609/the-strategic-defense-of-physician-autonomy-state-public-health-agencies-as-countervailing-powers
#6
Laura Senier, Rachael Lee, Lauren Nicoll
Advances in genetic testing and the aggressive marketing of genetic tests by commercial diagnostic laboratories have driven both consumer demand and the need for unbiased information about how tests should guide healthcare delivery. This paper uses the countervailing powers framework to explore the role of state public health agencies as arbiters of quality and safety, specifically through their efforts to encourage physicians to follow evidence-based recommendations for screening for hereditary cancers. Social scientists have often viewed actions by the state to regulate cost, quality, or safety as a threat to physician autonomy...
August 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28544082/a-resource-of-potential-drug-targets-and-strategic-decision-making-for-obstructive-sleep-apnoea-pharmacotherapy
#7
REVIEW
Richard L Horner, Kevin P Grace, Andrew Wellman
There is currently no pharmacotherapy for obstructive sleep apnoea (OSA) but there is no principled a priori reason why there should not be one. This review identifies a rational decision-making strategy with the necessary logical underpinnings that any reasonable approach would be expected to navigate to develop a viable pharmacotherapy for OSA. The process first involves phenotyping an individual to quantify and characterize the critical predisposing factor(s) to their OSA pathogenesis and identify, a priori, if the patient is likely to benefit from a pharmacotherapy that targets those factors...
July 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28485693/rapid-assessment-of-facilitators-and-barriers-related-to-the-acceptance-challenges-and-community-perception-of-daily-regimen-for-treating-tuberculosis-in-india
#8
Himanshu Negandhi, Ritika Tiwari, Anjali Sharma, Rajesh Nair, Sanjay Zodpey, Ramesh Reddy Allam, Ganesh Oruganti
INTRODUCTION: The Revised National Tuberculosis Control Program (RNTCP) is the largest tuberculosis (TB) control program in the world based on Directly Observed Treatment Short-Course (DOTS) strategy. Globally, most countries have been using a daily regimen and in India a shift towards a daily regimen for TB treatment has already begun. The daily strategy is known to improve program coverage along with compliance. Such strategic shifts have both management and operational implications...
2017: Global Health Action
https://www.readbyqxmd.com/read/28482180/the-development-of-multitasking-in-children-aged-7-12years-evidence-from-cross-sectional-and-longitudinal-data
#9
Tian-Xiao Yang, Weizhen Xie, Chu-Sheng Chen, Mareike Altgassen, Ya Wang, Eric F C Cheung, Raymond C K Chan
This study investigated the development of multitasking ability across childhood. A sample of 65 typically developing children aged 7, 9, and 11years completed two multitasking tests across three time points within a year. Cross-sectional and longitudinal data consistently indicated continuous linear growth in children's multitasking ability. By the age of 12years, children could effectively perform a simple multitasking scenario comprising six equally important tasks, although their ability to strategically organize assorted tasks with varied values and priorities in a complex multitasking setting had not reached proficiency yet...
September 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28356212/the-use-of-think-aloud-protocols-to-identify-a-decision-making-process-of-community-pharmacists-aimed-at-improving-cms-star-ratings-scores
#10
David L George, Michael J Smith, JoLaine R Draugalis, Eleni L Tolma, Shellie L Keast, Justin B Wilson
BACKGROUND: The Center for Medicare and Medicaid Services (CMS) created the Star Rating system based on multiple measures that indicate the overall quality of health plans. Community pharmacists can impact certain Star Ratings measure scores through medication adherence and patient safety interventions. OBJECTIVE: To explore methods, needs, and workflow issues of community pharmacists to improve CMS Star Ratings measures. METHODS: Think-aloud protocols (TAPs) were conducted with active community retail pharmacists in Oklahoma...
March 22, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28339590/reducing-antimicrobial-use-in-an-academic-pediatric-institution-evaluation-of-the-effectiveness-of-a-prospective-audit-with-real-time-feedback
#11
Zachary I Willis, Jessica Gillon, Meng Xu, James C Slaughter, M Cecilia Di Pentima
Introduction: Antimicrobial use is decreasing across freestanding children's hospitals, predominantly in institutions with antimicrobial stewardship programs (ASPs) in place. A highly effective ASP should effect a greater decrease in use than predicted by existing trends. Antimicrobial stewardship programs depend on clinician adherence to program recommendations, but little is known about factors associated with adherence. Methods: Parenteral antimicrobial-use data for our institution and 43 additional freestanding children's hospitals were obtained and normalized for patient census...
October 7, 2016: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28288178/can-application-and-transfer-of-strategy-be-observed-in-low-visibility-condition
#12
Imen El Karoui, Kalliopi Christoforidis, Lionel Naccache
It has been long assumed that cognitive control processes can only be applied on consciously visible stimuli, but empirical evidence is contradictory. In the present study, we investigated strategic adaptation to conflict both in unmasked and in low-visibility masked trials. Using a paradigm derived from the Stroop task, we studied the application of strategies, but also the transfer of a strategy developed in unmasked trials to masked trials, and the trial-to-trial dynamics of strategic processing. In unmasked trials, we found evidence of strategic adaptation to conflict, both in reaction times and in ERPs (N2 and P300)...
2017: PloS One
https://www.readbyqxmd.com/read/28207500/strategic-use-of-dual-regimens-of-boosted-protease-inhibitors-plus-maraviroc-in-poorly-adherent-subjects-in-view-of-long-acting-drugs-a-retrospective-study
#13
Amedeo Ferdinando Capetti, Mariangela Micale, Laura Carenzi, Fosca Niero, Simona Landonio, Stefania Vimercati, Gianfranco Dedivitiis, Giuliano Rizzardini
In view of the forthcoming long-acting antiretrovirals, measures should be taken to prevent the selection of HIV drug resistance mutations. All subjects who had been switched to boosted protease inhibitors plus maraviroc (bPIs/MVC) with baseline HIV-1 RNA >50 copies/mL between June, 2014, and April, 2015, were retrospectively evaluated. HIV-1 RNA, CD4+ T-cells, serum glucose, creatinine, ALT, and adverse events were controlled every 3 to 4 months. We retrospectively analyzed 44 patients: 18 were taking darunavir/ritonavir (DRV/r) and 26 atazanavir/ritonavir (ATV/r) once daily, plus MVC 300 mg once daily...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28130505/a-national-evaluation-using-standardised-patient-actors-to-assess-sti-services-in-public-sector-clinical-sentinel-surveillance-facilities-in-south-africa
#14
MULTICENTER STUDY
Pamela K Kohler, Eva Marumo, Suzanne L Jed, Gladys Mema, Sean Galagan, Kenneth Tapia, Erushka Pillay, Julia DeKadt, Evasen Naidoo, Julia C Dombrowski, King K Holmes
OBJECTIVES: Quality concerns in STI service delivery and missed opportunities for integration with HIV testing and prevention services in South Africa have been well documented. This national evaluation aimed to evaluate current utilisation and adherence to national STI guidelines, including partner notification and integration with HIV services, for diagnosis and management of STIs. METHODS: Facility surveys assessed infrastructure and resource availability, and standardised patient (SP) assessments evaluated quality of STI care in 50 public clinics in nine provinces in South Africa...
June 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28122765/random-number-generation-in-hiv-disease-associations-with-neuropsychological-functions-and-activities-of-daily-living
#15
David P Sheppard, Steven Paul Woods, Katie L Doyle, Marizela Verduzco
OBJECTIVE: HIV is associated with frontostriatal dysregulation and executive dysfunction. This study evaluated whether HIV-infected individuals evidence deficits in random number generation (RNG), which is a strategic task requiring paced, rule-guided production of digits. METHOD: In total, 74 HIV+ adults and 54 seronegative comparison participants completed a comprehensive research neuropsychological battery. Participants produced a random digit sequence by avoiding any order and using numbers 1 through 10 for 100 s at a pace of 1 digit/s...
February 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28027668/social-determinants-of-health-and-retention-in-hiv-care-in-a-clinical-cohort-in-ontario-canada
#16
Beth Rachlis, Ann N Burchell, Sandra Gardner, Lucia Light, Janet Raboud, Tony Antoniou, Jean Bacon, Anita Benoit, Curtis Cooper, Claire Kendall, Mona Loutfy, Wendy Wobeser, Frank McGee, Anita Rachlis, Sean B Rourke
Continuous HIV care supports antiretroviral therapy initiation and adherence, and prolongs survival. We investigated the association of social determinants of health (SDH) and subsequent retention in HIV care in a clinical cohort in Ontario, Canada. The Ontario HIV Treatment Network Cohort Study is a multi-site cohort of patients at 10 HIV clinics. Data were collected from medical charts, interviews, and via record linkage with the provincial public health laboratory for viral load tests. For participants interviewed in 2009, we used three-category multinomial logistic regression to identify predictors of retention in 2010-2012, defined as (1) continuous care (≥2 viral loads ≥90 days in all years; reference category); (2) discontinuous care (only 1 viral load/year in ≥1 year); and (3) a gap in care (≥1 year in 2010-2012 with no viral load)...
December 27, 2016: AIDS Care
https://www.readbyqxmd.com/read/28012339/rare-nodular-malignant-melanoma-of-the-heel-in-the-caribbean-a-case-report
#17
Wayne A Warner, Vandana Devika Sookdeo, Srikanth Umakanthan, Kevin Sarran, Lemuel Pran, Maurice Fortuné, Wesley Greaves, Sharda Narinesingh, Dave Harnanan, Ravi Maharaj
INTRODUCTION: Malignant melanoma of the heel is a rare melanoma subtype with incidence rates that reflect the complex relationship between sun exposure at certain geographic locations, individual melanin levels and overall melanoma risk. It is oftentimes characterized by poor prognosis because of delays in presentation resulting in longitudinal tumor invasion, lymph node involvement and metastasis. PRESENTATION OF CASE: A 59-year-old woman was admitted to the Eric Williams Medical Sciences Complex, Trinidad and Tobago with a 5mm pruritic lesion on her left heel...
November 27, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27930606/a-framework-for-health-communication-across-the-hiv-treatment-continuum
#18
Stella Babalola, Lynn M Van Lith, Elizabeth C Mallalieu, Zoe R Packman, Emily Myers, Kim Seifert Ahanda, Emily Harris, Tilly Gurman, Maria-Elena Figueroa
BACKGROUND: As test and treat rolls out, effective interventions are needed to address the determinants of outcomes across the HIV treatment continuum and ensure that people infected with HIV are promptly tested, initiate treatment early, adhere to treatment, and are virally suppressed. Communication approaches offer viable options for promoting relevant behaviors across the continuum. CONCEPTUAL FRAMEWORK: This article introduces a conceptual framework, which can guide the development of effective health communication interventions and activities that aim to impact behaviors across the HIV treatment continuum in low- and medium-income countries...
January 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27923008/a-framework-for-health-communication-across-the-hiv-treatment-continuum
#19
Stella Babalola, Lynn M Van Lith, Elizabeth C Mallalieu, Zoe R Packman, Emily Myers, Kim Seifert Ahanda, Emily Harris, Tilly Gurman, Maria-Elena Figueroa
BACKGROUND: As test and treat rolls out, effective interventions are needed to address the determinants of outcomes across the HIV treatment continuum and ensure that people infected with HIV are promptly tested, initiate treatment early, adhere to treatment, and are virally suppressed. Communication approaches offer viable options for promoting relevant behaviors across the continuum. CONCEPTUAL FRAMEWORK: This article introduces a conceptual framework, which can guide the development of effective health communication interventions and activities that aim to impact behaviors across the HIV treatment continuum in low- and medium-income countries...
January 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/27894229/-self-reported-experience-in-patients-treated-with-hepatitis-c-direct-acting-antivirals
#20
Irene Cañamares Orbis, Javier Saez de la Fuente, Ismael Escobar Rodriguez, Concepción Esteban Alba, Ana Such Díaz, Ismael Escobar Rodríguez
BACKGROUND AND OBJECTIVE: To learn about and analyze the self-reported treatment experience of HCV patients who started treatment with direct acting antivirals agents (DAA), at a real-time, proactive and integrated into the pharmaceutical care healthcare process, using a prospective questionnaire completed by patients as clinical tool. MATERIAL AND METHODS: Observational and cross-sectional study conducted between April (start of the National Strategic Plan) and December 2015 in the Outpatient Pharmacy Service...
November 1, 2016: Farmacia Hospitalaria
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