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Strategic adherence

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https://www.readbyqxmd.com/read/28901787/medication-management-strategies-used-by-older-adults-with-heart-failure-a-systems-based-analysis
#1
Robin S Mickelson, Richard J Holden
BACKGROUND: Older adults with heart failure use strategies to cope with the constraining barriers impeding medication management. Strategies are behavioral adaptations that allow goal achievement despite these constraining conditions. When strategies do not exist, are ineffective or maladaptive, medication performance and health outcomes are at risk. While constraints to medication adherence are described in literature, strategies used by patients to manage medications are less well-described or understood...
September 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28877623/management-challenges-in-british-columbia-s-healthcare-system
#2
Howard Peter Greenwald
Purpose The purpose of this paper is to identify the operational and management challenges in a globally budgeted, regionalized healthcare system and their implications for public service. Design/methodology/approach Concentrating on British Columbia's regional health authorities (RHAs) and hospitals, this study utilized data from interviews of key informants, documents (histories, legislation, agreements between RHAs and provincial government, and RHA organizational charts), news reports, and participant observation at board meetings...
June 19, 2017: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/28870152/subjective-patient-reported-versus-objective-adherence-to-subcutaneous-interferon-%C3%AE-1a-in-multiple-sclerosis-using-rebismart%C3%A2-the-core-study
#3
Chiara Zecca, Giulio Disanto, Sarah Mühl, Claudio Gobbi
BACKGROUND: Patient adherence to treatment is key to preventing the worsening of neurological disability in multiple sclerosis (MS). The RebiSmart® autoinjector facilitates self-administration of subcutaneous interferon β-1a (sc IFN β-1a) and records objective adherence data. The CORE study was undertaken to evaluate the relationship between subjectively reported and objective adherence of MS patients using RebiSmart® in Switzerland and explore variables associated with objective adherence...
September 4, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28866988/a-new-generation-computerised-metacognitive-cognitive-remediation-programme-for-schizophrenia-circuits-a-randomised-controlled-trial
#4
C Reeder, V Huddy, M Cella, R Taylor, K Greenwood, S Landau, T Wykes
BACKGROUND: Cognitive remediation (CR) is a psychological therapy, which improves cognitive and social functioning in people with schizophrenia. It is now being implemented within routine clinical services and mechanisms of change are being explored. We designed a new generation computerised CR programme, CIRCuiTS (Computerised Interactive Remediation of Cognition - a Training for Schizophrenia), to enhance strategic and metacognitive processing, with an integrated focus on the transfer of cognitive skills to daily living...
September 4, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28859470/medication-nonadherence-in-korean-patients-with-rheumatoid-arthritis-the-importance-of-belief-about-medication-and-illness-perception
#5
Young Sun Suh, Yun-Hong Cheon, Hyun-Ok Kim, Rock-Bum Kim, Ki Soo Park, Sang-Hyon Kim, Seung-Geun Lee, Eun-Kyoung Park, Jian Hur, Sang-Il Lee
Background/Aims: To investigate medication nonadherence in Korean patients with rheumatoid arthritis (RA) and analyze related factors. Methods: A total of 292 patients with RA participated in this study. Medication nonadherence, intentional or unintentional, was gauged via self-reported questionnaire. Patient perceptions of illness, treatment beliefs, and moods were measured via Brief Illness Perception Questionnaire, Beliefs about Medicines Questionnaire, and Patient Health Questionnaire-2, respectively...
April 20, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28837563/demographic-clinical-and-behavioural-determinants-of-hiv-serostatus-non-disclosure-to-sex-partners-among-hiv-infected-pregnant-women-in-the-eastern-cape-south-africa
#6
Oladele Vincent Adeniyi, Anthony Idowu Ajayi, Nonkosi Selanto-Chairman, Daniel Ter Goon, Gerry Boon, Yusimi Ordaz Fuentes, George Justus Hofmeyr, Gordana Avramovic, Craig Carty, John Lambert
OBJECTIVES: Drawing from a baseline sample of a cohort study, the study examines the extent and correlates of serostatus non-disclosure to sex partners and family members, and reasons for non-disclosure among HIV-infected pregnant women in the Eastern Cape Province, South Africa. METHODS: This longitudinal cohort study recruited 1709 pregnant women living with HIV who attended three of the largest maternity centres in the Eastern Cape, South Africa, for delivery between September 2015 and May 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28760901/synthetic-porcine-hepcidin-exerts-opposite-roles-in-escherichia-coli-and-salmonella-infections
#7
Dan Liu, Zhen-Shun Gan, Wan Ma, Hai-Tao Xiong, Yun-Qing Li, Yi-Zhen Wang, Hua-Hua Du
Hepcidin, an antimicrobial peptide, was discovered to integrate diverse signals from iron status and infection threat and orchestrate a series of host protective responses. There have been several studies investigating the antimicrobial role of hepcidin but controversial. Here, we aim to examine the role of hepcidin in bacterial adherence and invasion in vitro We found that porcine hepcidin could decrease the amount of extracellular pathogen enterotoxigenic Escherichia coli (ETEC) K88 that adhered to cells by aggregating bacteria...
July 31, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28702176/monitoring-and-evaluating-the-adherence-to-a-complementary-food-supplement-ying-yang-bao-among-young-children-in-rural-qinghai-china-a-mixed-methods-evaluation-study
#8
Qiong Wu, Yanfeng Zhang, Suying Chang, Wei Wang, Michelle Helena van Velthoven, Huijun Han, Min Xing, Li Chen, Xiaozhen Du, Robert W Scherpbier
BACKGROUND: Large investments are currently made in community-based complementary food supplement (Ying Yang Bao, YYB) programs to improve nutrition of young children in rural areas in China. However, there is a lack of knowledge about the experience and challenges of implementing YYB programs in China. We aimed to: 1) monitor distribution of YYB; 2) assess children's adherence to and acceptability of YYB; and 3) evaluate community-based strategies to improve the program. METHODS: This mixed methods evaluation study combined data from surveys and focus groups that took place during a controlled interventional evaluation trial...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28684081/self-reported-adherence-to-diet-and-preferences-towards-type-of-meal-plan-in-patient-with-type-2-diabetes-mellitus-a-cross-sectional-study
#9
V Ponzo, R Rosato, E Tarsia, I Goitre, F De Michieli, M Fadda, T Monge, A Pezzana, F Broglio, S Bo
BACKGROUND AND AIMS: Few studies have evaluated the attitudes of patients with type 2 diabetes mellitus (T2DM) towards the given dietary plans. In this study, we aimed to evaluate: i) the self-reported adherence of T2DM patients to the prescribed diets; ii) the use of other types of diet schemes; iii) the patients' preferences towards the type of meal plans. METHODS AND RESULTS: A 16 multiple-choice items questionnaire was administered to 500 T2DM patients; 71.2% (356/500) of them had the perception of having received a dietary plan; only 163/356 declared to be fully adherent...
July 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28673254/a-cross-sectional-study-to-evaluate-second-line-virological-failure-and-elevated-bilirubin-as-a-surrogate-for-adherence-to-atazanavir-ritonavir-in-two-urban-hiv-clinics-in-lilongwe-malawi
#10
Dennis Miyoge Ongubo, Robertino Lim, Hannock Tweya, Christopher Chikhosi Stanley, Petros Tembo, Richard Broadhurst, Salem Gugsa, McNeil Ngongondo, Colin Speight, Tom Heller, Sam Phiri, Mina C Hosseinipour
BACKGROUND: Malawi's national antiretroviral therapy program provides atazanavir/ritonavir-based second line regimens which cause concentration-dependent rise in indirect bilirubin. We sought to determine if elevated bilirubin, as a surrogate of atazanavir/ritonavir adherence, can aid in the evaluation of second line virological failure in Malawi. METHODS: We conducted a cross-sectional study of HIV-infected patients ≥15 years who were on boosted protease inhibitor-based second line antiretroviral therapy for at least 6 months in two urban HIV clinics in Lilongwe, Malawi...
July 3, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28671699/developing-new-platform-chemicals-what-is-required-for-a-new-bio-based-molecule-to-become-a-platform-chemical-in-the-bioeconomy
#11
José-Vitor Bomtempo, Flavia Chaves Alves, Fabio de Almeida Oroski
This paper proposes a framework with six dimensions that can be useful for evaluating the potential and the current stage of a bio-based platform chemical. The framework considers the technological and strategic challenges to be fulfilled by a company that intends to lead a platform based on a bio-based chemical. A platform chemical should be an intermediate molecule, with a structure able to generate a number of derivatives, that is produced at a competitive cost, capable of allowing exploitation of the scale and scope economies, and inserted within a complete innovation ecosystem that is able to create value with governance mechanisms that are capable of allowing coordination of the innovation process and facilitation of the value capture by the focal company leading the platform, in our case the producer of the platform molecule...
July 3, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28634619/implementation-of-li-rads-into-a-radiological-practice
#12
REVIEW
Stefan T Siedlikowski, Ania Z Kielar, Eleanor L Ormsby, Bijan Bijan, Christopher Kagay
Since its introduction in 2011, Liver Imaging Reporting and Data System (LI-RADS) has become an increasingly utilized method for radiologists to categorize lesions for hepatocellular carcinoma (HCC) in patients at risk (American College of Radiology, www.acr.org/quality-safety/resources/lirads 2016). This overview article presents insight into methods of incorporating LI-RADS into an existing clinical practice, highlighting concrete ways to establish this system as a mainstay in any radiologist's evidence-based armamentarium...
June 20, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28622609/the-strategic-defense-of-physician-autonomy-state-public-health-agencies-as-countervailing-powers
#13
Laura Senier, Rachael Lee, Lauren Nicoll
Advances in genetic testing and the aggressive marketing of genetic tests by commercial diagnostic laboratories have driven both consumer demand and the need for unbiased information about how tests should guide healthcare delivery. This paper uses the countervailing powers framework to explore the role of state public health agencies as arbiters of quality and safety, specifically through their efforts to encourage physicians to follow evidence-based recommendations for screening for hereditary cancers. Social scientists have often viewed actions by the state to regulate cost, quality, or safety as a threat to physician autonomy...
August 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28544082/a-resource-of-potential-drug-targets-and-strategic-decision-making-for-obstructive-sleep-apnoea-pharmacotherapy
#14
REVIEW
Richard L Horner, Kevin P Grace, Andrew Wellman
There is currently no pharmacotherapy for obstructive sleep apnoea (OSA) but there is no principled a priori reason why there should not be one. This review identifies a rational decision-making strategy with the necessary logical underpinnings that any reasonable approach would be expected to navigate to develop a viable pharmacotherapy for OSA. The process first involves phenotyping an individual to quantify and characterize the critical predisposing factor(s) to their OSA pathogenesis and identify, a priori, if the patient is likely to benefit from a pharmacotherapy that targets those factors...
July 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28485693/rapid-assessment-of-facilitators-and-barriers-related-to-the-acceptance-challenges-and-community-perception-of-daily-regimen-for-treating-tuberculosis-in-india
#15
Himanshu Negandhi, Ritika Tiwari, Anjali Sharma, Rajesh Nair, Sanjay Zodpey, Ramesh Reddy Allam, Ganesh Oruganti
INTRODUCTION: The Revised National Tuberculosis Control Program (RNTCP) is the largest tuberculosis (TB) control program in the world based on Directly Observed Treatment Short-Course (DOTS) strategy. Globally, most countries have been using a daily regimen and in India a shift towards a daily regimen for TB treatment has already begun. The daily strategy is known to improve program coverage along with compliance. Such strategic shifts have both management and operational implications...
2017: Global Health Action
https://www.readbyqxmd.com/read/28482180/the-development-of-multitasking-in-children-aged-7-12years-evidence-from-cross-sectional-and-longitudinal-data
#16
Tian-Xiao Yang, Weizhen Xie, Chu-Sheng Chen, Mareike Altgassen, Ya Wang, Eric F C Cheung, Raymond C K Chan
This study investigated the development of multitasking ability across childhood. A sample of 65 typically developing children aged 7, 9, and 11years completed two multitasking tests across three time points within a year. Cross-sectional and longitudinal data consistently indicated continuous linear growth in children's multitasking ability. By the age of 12years, children could effectively perform a simple multitasking scenario comprising six equally important tasks, although their ability to strategically organize assorted tasks with varied values and priorities in a complex multitasking setting had not reached proficiency yet...
September 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28356212/the-use-of-think-aloud-protocols-to-identify-a-decision-making-process-of-community-pharmacists-aimed-at-improving-cms-star-ratings-scores
#17
David L George, Michael J Smith, JoLaine R Draugalis, Eleni L Tolma, Shellie L Keast, Justin B Wilson
BACKGROUND: The Center for Medicare and Medicaid Services (CMS) created the Star Rating system based on multiple measures that indicate the overall quality of health plans. Community pharmacists can impact certain Star Ratings measure scores through medication adherence and patient safety interventions. OBJECTIVE: To explore methods, needs, and workflow issues of community pharmacists to improve CMS Star Ratings measures. METHODS: Think-aloud protocols (TAPs) were conducted with active community retail pharmacists in Oklahoma...
March 22, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28339590/reducing-antimicrobial-use-in-an-academic-pediatric-institution-evaluation-of-the-effectiveness-of-a-prospective-audit-with-real-time-feedback
#18
Zachary I Willis, Jessica Gillon, Meng Xu, James C Slaughter, M Cecilia Di Pentima
Introduction: Antimicrobial use is decreasing across freestanding children's hospitals, predominantly in institutions with antimicrobial stewardship programs (ASPs) in place. A highly effective ASP should effect a greater decrease in use than predicted by existing trends. Antimicrobial stewardship programs depend on clinician adherence to program recommendations, but little is known about factors associated with adherence. Methods: Parenteral antimicrobial-use data for our institution and 43 additional freestanding children's hospitals were obtained and normalized for patient census...
October 7, 2016: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28288178/can-application-and-transfer-of-strategy-be-observed-in-low-visibility-condition
#19
Imen El Karoui, Kalliopi Christoforidis, Lionel Naccache
It has been long assumed that cognitive control processes can only be applied on consciously visible stimuli, but empirical evidence is contradictory. In the present study, we investigated strategic adaptation to conflict both in unmasked and in low-visibility masked trials. Using a paradigm derived from the Stroop task, we studied the application of strategies, but also the transfer of a strategy developed in unmasked trials to masked trials, and the trial-to-trial dynamics of strategic processing. In unmasked trials, we found evidence of strategic adaptation to conflict, both in reaction times and in ERPs (N2 and P300)...
2017: PloS One
https://www.readbyqxmd.com/read/28207500/strategic-use-of-dual-regimens-of-boosted-protease-inhibitors-plus-maraviroc-in-poorly-adherent-subjects-in-view-of-long-acting-drugs-a-retrospective-study
#20
Amedeo Ferdinando Capetti, Mariangela Micale, Laura Carenzi, Fosca Niero, Simona Landonio, Stefania Vimercati, Gianfranco Dedivitiis, Giuliano Rizzardini
In view of the forthcoming long-acting antiretrovirals, measures should be taken to prevent the selection of HIV drug resistance mutations. All subjects who had been switched to boosted protease inhibitors plus maraviroc (bPIs/MVC) with baseline HIV-1 RNA >50 copies/mL between June, 2014, and April, 2015, were retrospectively evaluated. HIV-1 RNA, CD4+ T-cells, serum glucose, creatinine, ALT, and adverse events were controlled every 3 to 4 months. We retrospectively analyzed 44 patients: 18 were taking darunavir/ritonavir (DRV/r) and 26 atazanavir/ritonavir (ATV/r) once daily, plus MVC 300 mg once daily...
February 2017: Medicine (Baltimore)
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