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https://www.readbyqxmd.com/read/28214166/sleeve-gastrectomy-in-the-elderly-a-case-control-study-with-long-term-follow-up-of-3-years
#1
Andrés Navarrete, Ricard Corcelles, Gabriel Diaz Del Gobbo, Sofía Perez, Josep Vidal, Antonio Lacy
BACKGROUND: Advanced age is considered to be a relative contraindication to bariatric surgery because of increased perioperative risk and suboptimal excess weight loss. OBJECTIVES: The aim of this study was to analyze the safety and effectiveness of the sleeve gastrectomy (SG) procedure in a cohort of elderly patients (aged≥60 yr) compared with younger patients (aged<60 yr). SETTING: Hospital clinic, Barcelona, Spain. METHODS: A retrospective analysis of all cases of SG in patients≥60 years old between January 2006 and December 2012 was performed...
December 14, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28210308/my-night-on-call-in-spain
#2
Iñigo Ojanguren
The day starts at 8:00 h with a clinical session in the Respiratory Service of the Vall d'Hebron University Hospital, in Barcelona, Spain; from 8:00 to 9:00 h, a colleague discusses and explains to the rest of the department the most important articles published in the past month in his assigned respiratory journal. I run out at 8:55 h as I am about to start a respiratory outpatient clinic, where I will see 24 patients over the next few hours. Hopefully I'll have a break at 15:00 h so that I have the opportunity to have lunch and recover my energy to immerse myself in the evening-night shift...
September 2016: Breathe
https://www.readbyqxmd.com/read/28209963/the-impact-of-esophagogastric-varices-on-the-prognosis-of-patients-with-hepatocellular-carcinoma
#3
Wei-Yao Hsieh, Ping-Hsien Chen, I-Yen Lin, Chien-Wei Su, Yee- Chao, Teh-Ia Huo, Yi-Hsiang Huang, Ming-Chih Hou, Han-Chieh Lin, Jaw-Ching Wu
Whether or not esophagogastric varices (EGV) could determine the outcomes of patients with hepatocellular carcinoma (HCC) is still unclear. A total of 990 treatment-naive HCC patients who received an esophagogastroduodenoscopy at the time of HCC diagnosis were retrospectively enrolled. The factors in terms of prognosis were analyzed by Cox proportional hazards model and propensity score matching analysis. Among the enrolled patients, 480 (48.5%) patients had EGV. Patients with EGV had a significantly lower cumulative 5-year survival rate than those without EGV (24...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28196467/cost-effectiveness-of-strategies-to-increase-screening-coverage-for-cervical-cancer-in-spain-the-criverva-study
#4
Marta Trapero-Bertran, Amelia Acera Pérez, Silvia de Sanjosé, Josep Maria Manresa Domínguez, Diego Rodríguez Capriles, Ana Rodriguez Martinez, Josep Maria Bonet Simó, Norman Sanchez Sanchez, Pablo Hidalgo Valls, Mireia Díaz Sanchis
BACKGROUND: The aim of the study is to carry out a cost-effectiveness analysis of three different interventions to promote the uptake of screening for cervical cancer in general practice in the county of Valles Occidental, Barcelona, Spain. METHODS: Women aged from 30 to 70 years (n = 15,965) were asked to attend a general practice to be screened. They were randomly allocated to one of four groups: no intervention group (NIG); one group where women received an invitation letter to participate in the screening (IG1); one group where women received an invitation letter and informative leaflet (IG2); and one group where women received an invitation letter, an informative leaflet and a phone call reminder (IG3)...
February 14, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28196078/data-driven-system-to-predict-academic-grades-and-dropout
#5
Sergi Rovira, Eloi Puertas, Laura Igual
Nowadays, the role of a tutor is more important than ever to prevent students dropout and improve their academic performance. This work proposes a data-driven system to extract relevant information hidden in the student academic data and, thus, help tutors to offer their pupils a more proactive personal guidance. In particular, our system, based on machine learning techniques, makes predictions of dropout intention and courses grades of students, as well as personalized course recommendations. Moreover, we present different visualizations which help in the interpretation of the results...
2017: PloS One
https://www.readbyqxmd.com/read/28195873/niace-score-for-hepatocellular-carcinoma-patients-treated-by-surgery-or-transarterial-chemoembolization
#6
Xavier Adhoute, Guillaume Pénaranda, Jean Luc Raoul, Emilie Bollon, Bernard Pol, Yves P Letreut, Hervé Perrier, Olivier Bayle, Olivier Monnet, Patrick Beaurain, Cyril Muller, Jean Hardwigsen, Gaëlle Lefolgoc, Paul Castellani, Jean P Bronowicki, Marc Bourlière
BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) prognostic scores could be useful in addition to the Barcelona Clinic Liver Cancer (BCLC) system to clarify patient prognosis and guide treatment decision. The NIACE (tumor Nodularity, Infiltrative nature of the tumor, serum Alpha-fetoprotein level, Child-Pugh stage, ECOG performance status) score distinguishes different prognosis groups among BCLC A, B, and C HCC patients. Our aims are to evaluate the NIACE score and its additive value in two HCC cohorts treated either by surgery or by chemoembolization, and then according to the BCLC recommendations...
February 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28192235/high-hcv-subtype-heterogeneity-in-a-chronically-infected-general-population-revealed-by-high-resolution-hcv-subtyping
#7
Francisco Rodriguez-Frias, Leonardo Nieto, Josep Gregori, Damir Garcia-Cehic, Rosario Casillas, David Tabernero, Maria Homs, Maria Blasi, Marta Vila, Qian Chen, Victor Vargas, Lluís Castells, Lluís Viladomiu, Joan Genesca, Beatriz Minguez, Salvador Augustin, Judit Carbonell, Celia Perales, Maria Eugenia Soria, Miriam Asensio, Meritxell Llorens, Laura Ordeig, Cristina Godoy, Maria Buti, Rafael Esteban, Tomas Pumarola, Juan Ignacio Esteban, Josep Quer
OBJECTIVES: Accurately characterize the chronically-infected general HCV population in the Barcelona area by a highly sensitive subtyping method able to identify the 67 recognized hepatitis C virus (HCV) subtypes, and to discriminate mixed infections in a single individual. This information has strong implications on patient management, in deciding the optimal combination of direct-acting antivirals (DAAs) for each patient. METHODS: HCV subtyping by UDPS. All HCV patients who attended Vall d'Hebron Hospital outpatient clinics from February 2015 to May 2016 (N=1473) were included...
February 10, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28192185/hepatic-decompensation-is-the-major-driver-of-death-in-hcv-infected-cirrhotic-patients-with-successfully-treated-early-hepatocellular-carcinoma
#8
Giuseppe Cabibbo, Salvatore Petta, Marco Barbara, Simona Attardo, Laura Bucci, Fabio Farinati, Edoardo G Giannini, Giulia Negrini, Francesca Ciccarese, Gian Lodovico Rapaccini, Maria Di Marco, Eugenio Caturelli, Marco Zoli, Franco Borzio, Rodolfo Sacco, Roberto Virdone, Fabio Andrea Marra Mega, Filomena Morisco, Luisa Benvegnù, Antonio Gasbarrini, Gianluca Svegliati-Baroni, Francesco Giuseppe Foschi, Andrea Olivani, Alberto Masotto, Gerardo Nardone, Antonio Colecchia, Marcello Persico, Antonio Craxì, Franco Trevisani, Calogero Cammà
BACKGROUND & AIMS: A major problem in assessing the long-term outcome of HCV-infected cirrhotic patients with successfully treated Barcelona Clinic Liver Cancer (BCLC) A hepatocellular carcinoma (HCC) arises from the lack of models accounting for early changes during follow-up. AIM: of study is to estimate the impact on 5-year overall survival (OS) of early (occurring within 12 months after complete radiological response) time-dependents events (HCC recurrence or hepatic decompensation) in a large cohort of successfully treated HCC patients with HCV cirrhosis...
February 9, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28188509/anticoagulation-in-atrial-fibrillation-noac-prescribing-in-primary-health-care
#9
Carla Bastida, Núria Corominas, José Miguel Sotoca, Marina Rovira
Background Few studies assess the use of non-vitamin K antagonist oral anticoagulants (NOACs) in daily practice for the prevention of thromboembolic complications associated to nonvalvular atrial fibrillation (AF). Objectives Describe NOACs' use and analyze its prescribing pattern. Evaluate possible factors associated to adverse events (AEs) and the applicability of prescription support forms. Methods We included patients with AF treated with a NOAC during 2014 in three primary healthcare centers in Barcelona, Spain...
February 10, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28188189/vascular-invasion-and-metastasis-is-predictive-of-outcome-in-barcelona-clinic-liver-cancer-stage-c-hepatocellular-carcinoma
#10
Ali A Mokdad, Amit G Singal, Jorge A Marrero, Hao Zhu, Adam C Yopp
Background: Patients with Barcelona Clinic Liver Cancer (BCLC) stage C hepatocellular carcinoma (HCC) have variable long-term outcomes. Better delineation of prognosis is important for clinical trial enrollment and clinical practice in an era of precision medicine. We hypothesized that stratification of patients with BCLC stage C HCC by presence of vascular invasion and/or metastasis improves prognostic discrimination. Methods: Using a prospectively maintained database, we identified 234 patients diagnosed with BCLC stage C HCC between 2005 and 2015...
February 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28181987/-pelfi-project-recruitment-and-sociodemographic-characteristics-of-immigrant-and-autochthonous-families-from-alicante-and-barcelona-city-subcohorts
#11
Ana Cayuela-Mateo, José Miguel Martínez-Martínez, Laia Ferrer Serret, Emily Felt, Jordi Casabona I Barbarà, Francisco Collazos Sanchez, Elena Ronda-Pérez
This study is a part of the multi-centre project "Platform of Longitudinal Studies of Immigrant Families (PELFI)" of the Immigration and Health Subprogram of the CIBER-ESP. It describes the field work and data collection of two sub-cohorts of immigrant and native families, and their main socio-demographic characteristics. Prospective observational cohort study in carried out in Barcelona and Alicante, Spain. The study population is a a non-probabilistic sample of 180 families of Colombian, Ecuadorian and Moroccan origin and 50 families of Spanish origin...
February 9, 2017: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/28176511/prevalence-of-illicit-drug-use-at-the-end-of-pregnancy-a-cross-sectional-study-at-the-time-of-birth
#12
Amadeu Roca Comas, Joan S Vila Domènech, Joana Massa Solé, Patricia Timoneda Paz, Mar Peñas Boira, Francisco J Herrero Espinet, Josep Sánchez Jiménez, Anna Ballester Martínez
BACKGROUND: Drug use during pregnancy is associated with adverse perinatal outcomes. This study was conducted to assess the prevalence of consumption of drugs of abuse in pregnant women at the end of gestation. METHODS: Cross-sectional study of all consecutive pregnant women in labor admitted to a regional hospital in Calella (Barcelona, Spain) in labor over one year period (2014- 2015). Women who gave written consent to take part in the study provided a urine sample on admission and completed a questionnaire with toxic habits-related questions...
February 7, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28170405/treatment-algorithm-based-on-the-multivariate-survival-analyses-in-patients-with-advanced-hepatocellular-carcinoma-treated-with-trans-arterial-chemoembolization
#13
Hasmukh J Prajapati, Hyun S Kim
PURPOSE: To develop the treatment algorithm from multivariate survival analyses (MVA) in patients with Barcelona clinic liver cancer (BCLC) C (advanced) Hepatocellular carcinoma (HCC) patients treated with Trans-arterial Chemoembolization (TACE). METHODS: Consecutive unresectable and non-tranplantable patients with advanced HCC, who received DEB TACE were studied. A total of 238 patients (mean age, 62.4yrs) was included in the study. Survivals were analyzed according to different parameters from the time of the 1st DEB TACE...
2017: PloS One
https://www.readbyqxmd.com/read/28170052/illicit-drug-policy-in-spain-the-opinion-of-health-and-legal-professionals
#14
Paola Rossi, Ester Blay, Víctor Costela, Marta Torrens
The high frequency of criminal behaviour and related legal problems associated with substance addiction generates a field of interaction between legal and healthcare systems. This study was developed as a multicentre project to investigate the opinions of professionals from legal and healthcare systems about policies on illegal drugs and their implementation in practice. A multiple choice questionnaire designed ad hoc was administered to a sample of 230 professionals from legal and healthcare fields working in the cities of Barcelona, Granada and Bilbao...
January 12, 2017: Adicciones
https://www.readbyqxmd.com/read/28167552/pharmacokinetic-of-benznidazole-in-healthy-volunteers-implications-in-future-clinical-trials
#15
I Molina, F Salvador, A Sánchez-Montalvá, M A Artaza, R Moreno, L Perin, A Esquisabel, L Pinto, J L Pedraz
BACKGROUND: Despite its toxicity and low efficacy in the chronic phase, benznidazole is the drug of choice in Chagas disease. Scarce information about pharmacokinetics and pharmacodynamics of benznidazole has been published. METHODS: We performed a phase I, open-label, non-randomized pharmacokinetic study of benznidazole (Abarax®) conducted in 8 healthy adult volunteers at the Infectious Diseases Department of the Vall d'Hebron University Hospital (Barcelona, Spain)...
February 6, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28166821/deb-tace-for-intermediate-and-advanced-hcc-initial-experience-in-a-brazilian-cancer-center
#16
Jose Hugo Mendes Luz, Paula M Luz, Henrique S Martin, Hugo R Gouveia, Raphal Braz Levigard, Felipe Diniz Nogueira, Bernardo Caetano Rodrigues, Tiago Nepomuceno de Miranda, Marcelo Henrique Mamede
BACKGROUND: According to Barcelona Clinic Liver Cancer classification transarterial chemoembolization is indicated in patients with Hepatocellular Carcinoma in the intermediate stage. Drug-eluting microspheres can absorb and release the chemotherapeutic agent slowly for 14 days after its intra-arterial administration. This type of transarterial chemoembolization approach appears to provide at least equivalent effectiveness with less toxicity. METHODS: This is a prospective, single-center study, which evaluated 21 patients with intermediate and advanced hepatocellular carcinoma who underwent transarterial chemoembolization with drug-eluting microspheres...
February 6, 2017: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/28164648/validation-of-a-new-panel-of-automated-chemiluminescence-assays-for-anticardiolipin-antibodies-in-the-screening-for-antiphospholipid-syndrome
#17
D Janek, L Slavik, J Ulehlova, V Krcova, A Hlusi, J Prochazkova
BACKGROUND: Antibodies anticardiolipin (aCL) and anti-β2-glycoprotein I (aβ2GPI) are two of three laboratory criteria of antiphospholipid syndrome (APS). All of assays of antiphospholipid antibodies (aPL), coagulation assays as well as ELISAs, show methodological shortcomings, that affect their sensitivity and specificity. Therefore, we decided to validate these parameters for a new chemiluminescent examination (CLIA). METHODS: aCL and aβ2GPI antibodies were measured by ELISAs (AIDA, Bad Kreuznach, Germany) and aβ2GPI with CLIA kits (Werfen, Barcelona, Spain)...
July 1, 2016: Clinical Laboratory
https://www.readbyqxmd.com/read/28163603/rem-sleep-behavior-disorder-rbd-update-on-diagnosis-and-treatment
#18
Birgit Högl, Ambra Stefani
BACKGROUND: REM sleep behavior disorder (RBD) is parasomnia characterized by dream enactment and enabled by disruption of physiological muscle atonia during REM sleep. Over the past few years, diagnostic criteria and the methods used to confirm diagnosis have been updated. OBJECTIVE: In this review article, the current knowledge regarding RBD diagnosis and treatment is presented. METHODS: A selective literature search was carried out. RESULTS AND DISCUSSION: Although several RBD screening questionnaires have been developed, diagnosis can only be definitely confirmed on the basis of polysomnography...
2017: Somnologie: Schlafforschung und Schlafmedizin, Somnology: Sleep Research and Sleep Medicine
https://www.readbyqxmd.com/read/28161600/equine-viral-arteritis-in-breeding-and-sport-horses-in-central-spain
#19
Fatima Cruz-Lopez, Richard Newton, Ana Sanchez-Rodriguez, Joanne Ireland, Lapo Mughini-Gras, Miguel A Moreno, Paloma Fores
Equine viral arteritis (EVA) may have a high economic impact on breeding stud farms due to the occurrence of EVA-associated abortion outbreaks and the ability of the virus to persist in carrier stallions. While the consequences of EVA in premises with sport horses are usually less severe, the first confirmed outbreak of EVA in Spain occurred in a riding club in Barcelona, but no data on the seroprevalence of EVA in sport horses have been reported in Spain. Given the importance of both Spanish Purebred (SP) breeding horses and sport horses for Spain's equine industry, the aim of this study was to determine and compare the seroprevalence of EVA in these two horse populations in central Spain...
January 27, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28160422/survival-benefit-of-hepatic-resection-for-hepatocellular-carcinoma-beyond-the-barcelona-clinic-liver-cancer-classification
#20
Kenei Furukawa, Hiroaki Shiba, Takashi Horiuchi, Yoshihiro Shirai, Koichiro Haruki, Yuki Fujiwara, Taro Sakamoto, Takeshi Gocho, Katsuhiko Yanaga
BACKGROUND: The Barcelona Clinic Liver Cancer (BCLC) classification is the most widely used staging system for hepatocellular carcinoma (HCC), but its prognostic ability in patients after resection has not been yet validated. The aim of this study was to evaluate the BCLC classification among patients after resection. METHODS: The subjects were 196 patients who underwent hepatic resection for HCC between April 2003 and December 2014 at Jikei University Hospital...
February 3, 2017: Journal of Hepato-biliary-pancreatic Sciences
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