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Mohs Micrographic Surgery

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https://www.readbyqxmd.com/read/28195845/an-analysis-of-laser-therapy-for-the-treatment-of-nonmelanoma-skin-cancer
#1
Teo Soleymani, Michael Abrouk, Kristen M Kelly
BACKGROUND: Skin cancer remains the most prevalent type of cancer in the United States, and its burden on the health care system remains substantial. Standard treatments such as cryosurgery, electrodessication and curettage, topical and photodynamic therapies, and surgical excision including Mohs micrographic surgery are not without inherent morbidity, including risk of bleeding, infection, and scar. OBJECTIVE: Lasers may be an alternative for treatment of nonmelanoma skin cancer, and this paper reviews this therapeutic option...
February 9, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28181233/sebaceous-carcinoma-in-solid-organ-transplant-recipients
#2
Elika Hoss, Steven A Nelson, Amit Sharma
BACKGROUND: Though a rare tumor, sebaceous carcinoma is relatively well-described in immunocompetent patients, in whom it often occurs in a periorbital distribution where it has an overall poor prognosis with a high metastasis rate. The effect of transplant-related immunosuppression on the development of sebaceous carcinoma and its outcomes has not been characterized. METHODS: We collected 9 cases from a single institution of patients developing sebaceous carcinoma after solid organ transplantation...
February 8, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28178008/processing-adipose-rich-mohs-samples-a-comparative-study-of-effectiveness-of-pretreatment-with-liquid-nitrogen-versus-flash-freezing-spray
#3
Jeave Reserva, Zachary Kozel, Cindy Krol, Jodi Speiser, William Adams, Rebecca Tung
Processing of adipose-rich Mohs micrographic surgery (MMS) specimens poses challenges that may preclude complete margin evaluation. In this setting, the value of additional freezing methods using various cooling agents has not been previously investigated. The aim of this study is to compare the frozen section quality of high-adipose Mohs specimens processed without additional cooling treatments versus those pretreated with 1,1,1,2-tetrafluoroethane (TFE) or liquid nitrogen (LN2). A set of 3 sections were each taken from 24 adipose-rich Mohs micrographic surgery specimens...
January 26, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28178005/surgical-treatment-and-outcomes-of-patients-with-extramammary-paget-disease-a-cohort-study
#4
Sharon J Kim, Agnieszka K Thompson, Adeel S Zubair, Clark C Otley, Christopher J Arpey, Christian L Baum, Randall K Roenigk, Christine M Lohse, Jerry D Brewer
BACKGROUND: Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma occurring mainly in the anogenital region. Traditional management with wide local excision has shown high recurrence rates, thus Mohs micrographic surgery (MMS) has emerged as a promising treatment option. OBJECTIVE: To compare long-term outcomes after treatment with MMS or excision for primary EMPD. METHODS AND MATERIALS: Retrospective cohort review was conducted for 207 patients with EMPD treated at Mayo Clinic in Rochester, MN, between 1961 and 2012...
February 6, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28165350/sebaceous-carcinoma-treated-with-mohs-micrographic-surgery
#5
Kimberly L Brady, Eva A Hurst
BACKGROUND: Sebaceous carcinoma is a rare and potentially aggressive adnexal neoplasm with historic data indicating high rates of recurrence, metastasis, and cancer-specific mortality. OBJECTIVE: To evaluate the incidence of local recurrence, metastasis, disease-specific mortality, and all-cause mortality and to identify work-up approaches. PATIENTS AND METHODS/MATERIALS: Retrospective review of patients with sebaceous carcinoma treated with Mohs micrographic surgery between 2001 and 2013 at one institution...
February 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28139264/clinical-and-pathologic-factors-associated-with-subclinical-spread-of-invasive-melanoma
#6
Thuzar M Shin, Waqas R Shaikh, Jeremy R Etzkorn, Joseph F Sobanko, David J Margolis, Joel M Gelfand, Emily Y Chu, Rosalie Elenitsas, Christopher J Miller
BACKGROUND: Indications to treat invasive melanoma with Mohs micrographic surgery (MMS) or analogous techniques with exhaustive microscopic margin assessment have not been defined. OBJECTIVE: Identify clinical and histologic factors associated with subclinical spread of invasive melanoma. METHODS: This retrospective, cross-sectional study evaluated 216 invasive melanomas treated with MMS and melanoma antigen recognized by T cells 1 immunostaining...
January 28, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28135752/-vismodegib-therapy-for-periocular-basal-cell-carcinoma
#7
M Keserü, S Green, S Dulz
Background Basal cell carcinoma (BCC) is the commonest periorbital tumour. Mohs' micrographic surgery and secondary reconstruction is the therapeutic gold standard for periorbital BCC. In cases of inoperability for any reason, therapeutic alternatives are needed. Since the approval of vismodegib, an orally administered, targeted BCC therapy is available. Nevertheless there is little information on the use of vismodegib for periorbital BCC. Patients and Methods In a retrospective study, we analysed the data of 4 patients treated with vismodegib since 2014...
January 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28130559/basal-cell-carcinoma-arising-in-a-breast-augmentation-scar
#8
Lisa R Edwards, Nicole D Cresce, Mark A Russell
We report a case of a 46-year-old female who presented with a persistent lesion on the inferior right breast. The lesion was located within the scar from a breast augmentation procedure 12 years ago. The lesion had been treated as several conditions with no improvement. Biopsy revealed a superficial and nodular basal cell carcinoma, and the lesion was successfully removed with Mohs micrographic surgery. Basal cell carcinoma arising in a surgical scar is exceedingly rare with only 13 reported cases to date...
January 27, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28114205/two-suturing-techniques-for-the-prevention-and-treatment-of-nasal-valve-collapse-after-mohs-micrographic-surgery
#9
Anis Miladi, Joseph W McGowan, Heidi B Donnelly
BACKGROUND: Tumor extirpation of nonmelanoma skin cancer (NMSC) adjacent to the alar groove, using Mohs micrographic surgery (MMS), may risk causing internal nasal valve (INV) collapse, resulting in reduced airflow during inspiration. There are many surgical options described in the literature to repair INV collapse as a postoperative corrective procedure, but few exist as an intra-operative preventative procedure. OBJECTIVE: The authors present 2 distinct methods to prevent and treat INV collapse during the repair of a perialar surgical defect caused by MMS...
January 20, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28107593/patient-satisfaction-in-dermatology
#10
Emilie Brenaut, Claire-Alice De Salins, Laurent Misery, Anne-Marie Roguedas-Contios
We are pleased that there is a growing interest from doctors in patient'satisfaction. According to PubMed data and the key words 'patient' AND 'satisfaction', we found an impressive increase of the number of articles, from 179 in 1985 to 7,211 in 2015. We were highly interested by the lecture of the letter « Patient satisfaction and the waiting room in Mohs surgery: appropriate pre-warning may abrogate boredorm » from F.R. Ali, F. Al-Niaimi, E.E. Craythorne, R. Patalay and R. Mallipeddi and thank them for their interest in our paper...
January 20, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28107578/patient-satisfaction-and-the-waiting-room-in-mohs-surgery-appropriate-pre-warning-may-abrogate-boredom
#11
F R Ali, F Al-Niaimi, E E Craythorne, R Patalay, R Mallipeddi
Patient satisfaction in dermatology consultations has rightly been afforded attention by De Salins and colleagues.(1) When considering the patient journey through an outpatient appointment, a significant proportion of time is spent in the waiting room, a period which is poorly understood and may contribute to patient anxiety and perceived satisfaction with treatment.(2) In our outpatient Mohs micrographic surgery (MMS) unit, patients may be waiting for several hours in total whilst histological specimens are processed and analysed, prior to reconstruction, particularly if multiple MMS stages are needed...
January 20, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28099591/analysis-of-effectiveness-of-a-surgical-treatment-algorithm-for-basal-cell-carcinoma
#12
Flávio Barbosa Luz, Camila Ferron, Gilberto Perez Cardoso
BACKGROUND: Surgical excision is the treatment of choice for basal cell carcinoma and micrographic surgery considered the gold standard, however not yet used routinely worldwide available, as in Brazil. Considering this, a previously developed treatment guideline, which the majority of tumors were treated by conventional technique (not micrographic) was tested. OBJECTIVE: To establish the recurrence rate of basal cell carcinomas treated according to this guideline...
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28095571/effectiveness-of-the-mohs-and-close-technique-in-increasing-the-efficiency-of-a-mohs-micrographic-surgery
#13
Dhwani Mehta, Rebecca Jacobsen, Tonja Godsey, Brian Adams, Hugh Gloster
INTRODUCTION: Mohs micrographic surgery (MMS) is successful and cost effective, but may be time consuming as patients are required to wait for final wound repair until margins are clear. We propose for selected cases the "Mohs and Close technique" (MCT), in which the defect is immediately repaired after tumor resection rather than waiting until margins are clear. METHODS: MCT was only performed on tumors that had clearly de ned borders, low risk histology, whose resulting defect after exci- sion required either a primary or partial closure, and whose repair wouldn't change to a different repair option if further stages of exci- sion were necessary...
December 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28079637/ln2-cd10-and-ezrin-do-not-distinguish-between-atypical-fibroxanthoma-and-undifferentiated-pleomorphic-sarcoma-or-predict-clinical-outcome
#14
Allison Hanlon, Thomas Stasko, Dan Christiansen, Nika Cyrus, Anjela Galan
BACKGROUND: Atypical fibroxanthoma (AFX) is a rare cutaneous spindled cell neoplasm. For both diagnostic and therapeutic purposes, it is important to distinguish AFX from other poorly differentiated tumors, including undifferentiated pleomorphic sarcoma (UPS). OBJECTIVE: The authors aimed to identify the clinical, histologic, and immunohistochemical expression of LN2, ezrin, and CD10 in AFX and UPS tumors. METHODS AND MATERIALS: The authors retrospectively examined the charts of patients with AFX and UPS treated with Mohs micrographic surgery (MMS) at 2 academic institutions...
January 10, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28060173/squamous-cell-carcinoma-in-situ-upstaged-to-invasive-squamous-cell-carcinoma-a-5-year-single-institution-retrospective-review
#15
Sasima Eimpunth, Alina Goldenberg, Michael Shane Hamman, Gagik Oganesyan, Robert A Lee, Saowalak Hunnangkul, Silvia Soohyun Song, Tanya Greywal, Shang I Brian Jiang
BACKGROUND: Shave biopsy may not be able to accurately distinguish squamous cell carcinoma in situ (SCCIS) from invasive squamous cell carcinoma (SCC). Information on the incidence of biopsy-proven SCCIS upstaged to SCC after a more complete histologic examination is limited. OBJECTIVE: To determine the incidence and clinical risk factors associated with upstaging the biopsy diagnosis of SCCIS into invasive SCC based on findings during Mohs micrographic surgery (MMS)...
December 29, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28060172/applications-of-burow-s-grafts-in-the-reconstruction-of-mohs-micrographic-surgery-defects
#16
Anastasia Benoit, Brian C Leach, Joel Cook
BACKGROUND: Surgical defects in anatomically challenging locations, such as near free margins or crossing cosmetic subunits, may present reconstructive challenges to the dermatologic surgeon. For selected defects, Burow's grafts may produce functional and aesthetic results in a single operative session. OBJECTIVE: To describe the applications of the Burow's graft technique for the repair of defects after Mohs micrographic surgery. METHODS: An institutional review board-approved retrospective database review of surgical defects repaired with Burow's grafting after Mohs micrographic surgery at the Medical University of South Carolina was performed...
December 29, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28018683/nodular-fasciitis-complicating-a-staged-surgical-excision-of-dermatofibrosarcoma-protuberans
#17
C Helen Malone, Brandon Goodwin, Richard F Wagner, Vicente Resto, Brent Kelly
Dermatofibrosarcoma protuberans (DFSP) is an unusual spindle cell tumor with a high rate of local recurrence with traditional excision. Fortunately, Mohs micrographic surgery yields excellent cure rates for this neoplasm due to contiguous tumor spread and meticulous tumor mapping and margin analysis. We present the unique case of a patient treated with a modified Mohs technique with an analysis of the final margin with permanent sections, who developed a spindle cell neoplasm in the margins of her second stage excision consistent with nodular fasciitis...
2016: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/28005629/reconstruction-of-the-nipple-areola-complex-after-mohs-micrographic-surgery
#18
Zain Husain, Tiffany J Libby, David Ciocon
No abstract text is available yet for this article.
December 21, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28005628/effective-technique-for-periosteal-removal-during-mohs-micrographic-surgery
#19
Kachiu C Lee, Erich Karasko, Raymond Dufresne, Harold William Higgins
No abstract text is available yet for this article.
December 21, 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27990744/-en-face-ex-vivo-reflectance-confocal-microscopy-to-help-the-surgery-of-basal-cell-carcinoma-of-the-eyelid
#20
Marine Espinasse, Elisa Cinotti, Damien Grivet, Bruno Labeille, Virginie Prade, Catherine Douchet, Frédéric Cambazard, Gilles Thuret, Philippe Gain, Jean Luc Perrot
BACKGROUND: Fluorescence confocal microscopy (FCM) is a recent imaging technique for the examination of surgical cutaneous specimens and has been suggested as a fast alternative to Mohs micrographic surgery. Up-to-date it has been used in the fluorescence mode and with vertical sections of the specimen margins. The aim of this study was to evaluate FCM in the reflectance mode and with a horizontal ("en face") scanning of the surgical specimen in a series of basal cell carcinoma (BCC) of the eyelid...
December 19, 2016: Clinical & Experimental Ophthalmology
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