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https://www.readbyqxmd.com/read/27922605/pattern-of-structural-brain-changes-in-social-anxiety-disorder-after-cognitive-behavioral-group-therapy-a-longitudinal-multimodal-mri-study
#1
V R Steiger, A B Brühl, S Weidt, A Delsignore, M Rufer, L Jäncke, U Herwig, J Hänggi
Social anxiety disorder (SAD) is characterized by fears of social and performance situations. Cognitive behavioral group therapy (CBGT) has in general positive effects on symptoms, distress and avoidance in SAD. Prior studies found increased cortical volumes and decreased fractional anisotropy (FA) in SAD compared with healthy controls (HCs). Thirty-three participants diagnosed with SAD attended in a 10-week CBGT and were scanned before and after therapy. We applied three neuroimaging methods-surface-based morphometry, diffusion tensor imaging and network-based statistics-each with specific longitudinal processing protocols, to investigate CBGT-induced structural brain alterations of the gray and white matter (WM)...
December 6, 2016: Molecular Psychiatry
https://www.readbyqxmd.com/read/27918602/analytical-methods-based-on-the-light-scattering-of-plasmonic-nanoparticles-at-the-single-particle-level-with-dark-field-microscopy-imaging
#2
Tian Li, Xi Wu, Feng Liu, Na Li
This minireview summarizes analytical methods based on the light-scattering of plasmonic nanoparticles, primarily gold nanoparticles (AuNPs), at the single particle level from recent year publications. Examples are presented to illustrate simple and highly sensitive approaches based on AuNP localized surface plasmon resonance light-scattering with the dark-field microscopy imaging technology.
December 5, 2016: Analyst
https://www.readbyqxmd.com/read/27917203/population-genomics-diversity-of-plasmodium-falciparum-in-malaria-patients-attending-okelele-health-centre-okelele-ilorin-kwara-state-nigeria
#3
Olatunji Matthew Kolawole, Olugbenga Ayodeji Mokuolu, Yetunde Adeola Olukosi, Tolulope Ololade Oloyede
BACKGROUND: Plasmodium falciparum, the most dangerous malaria parasite species to humans remains an important public health concern in Okelele, a rural community in Ilorin, Kwara State, Nigeria. There is however little information about the genetic diversity of Plasmodium falciparum in Nigeria. OBJECTIVE: To determine the population genomic diversity of Plasmodium falciparum in malaria patients attending Okelele Community Healthcare Centre, Okelele, Ilorin, Kwara State...
September 2016: African Health Sciences
https://www.readbyqxmd.com/read/27914087/in-vitro-and-in-vivo-biofilm-formation-by-pathogenic-streptococci
#4
Yashuan Chao, Caroline Bergenfelz, Anders P Håkansson
This manuscript presents novel approaches to grow and evaluate Streptococcal biofilm formation using the human respiratory pathogen Streptococcus pneumoniae (the pneumococcus) as the main model organism on biological surfaces in vitro and in vivo. Most biofilm models are based on growth on abiotic surfaces, which is relevant for many pathogens whose growth on surfaces or medical devices is a major cause of disease transmission and infections, especially in hospital environments. However, most infections with commensal organisms require biofilm formation on biological surfaces in the host at the site of colonization or infection...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27911438/evolutionary-convergence-in-experimental-pseudomonas-populations
#5
Peter A Lind, Andrew D Farr, Paul B Rainey
Model microbial systems provide opportunity to understand the genetic bases of ecological traits, their evolution, regulation and fitness contributions. Experimental populations of Pseudomonas fluorescens rapidly diverge in spatially structured microcosms producing a range of surface-colonising forms. Despite divergent molecular routes, wrinkly spreader (WS) niche specialist types overproduce a cellulosic polymer allowing mat formation at the air-liquid interface and access to oxygen. Given the range of ways by which cells can form mats, such phenotypic parallelism is unexpected...
December 2, 2016: ISME Journal
https://www.readbyqxmd.com/read/27909654/bone-substitutes-and-expanders-in-spine-surgery-a-review-of-their-fusion-efficacies
#6
Abhijeet Kadam, Paul W Millhouse, Christopher K Kepler, Kris E Radcliff, Michael G Fehlings, Michael E Janssen, Rick C Sasso, James J Benedict, Alexander R Vaccaro
STUDY DESIGN: A narrative review of literature. OBJECTIVE: This manuscript intends to provide a review of clinically relevant bone substitutes and bone expanders for spinal surgery in terms of efficacy and associated clinical outcomes, as reported in contemporary spine literature. SUMMARY OF BACKGROUND DATA: Ever since the introduction of allograft as a substitute for autologous bone in spinal surgery, a sea of literature has surfaced, evaluating both established and newly emerging fusion alternatives...
2016: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/27907127/escherichia-coli-removal-in-biochar-modified-biofilters-effects-of-biofilm
#7
A R M Nabiul Afrooz, Alexandria B Boehm
The presence of microbial contaminants in urban stormwater is a significant concern for public health; however, their removal by traditional stormwater biofilters has been reported as inconsistent and inadequate. Recent work has explored the use of biochar to improve performance of stormwater biofilters under simplified conditions that do not consider potential effects of biofilm development on filter media. The present study investigates the role of biofilm on microbial contaminant removal performance of stormwater biofilters...
2016: PloS One
https://www.readbyqxmd.com/read/27904885/a-novel-protective-vaccine-antigen-from-the-core-escherichia-coli-genome
#8
Danilo G Moriel, Lendl Tan, Kelvin G K Goh, Minh-Duy Phan, Deepak S Ipe, Alvin W Lo, Kate M Peters, Glen C Ulett, Scott A Beatson, Mark A Schembri
Escherichia coli is a versatile pathogen capable of causing intestinal and extraintestinal infections that result in a huge burden of global human disease. The diversity of E. coli is reflected by its multiple different pathotypes and mosaic genome composition. E. coli strains are also a major driver of antibiotic resistance, emphasizing the urgent need for new treatment and prevention measures. Here, we used a large data set comprising 1,700 draft and complete genomes to define the core and accessory genome of E...
November 2016: MSphere
https://www.readbyqxmd.com/read/27904880/microbial-community-patterns-associated-with-automated-teller-machine-keypads-in-new-york-city
#9
Holly M Bik, Julia M Maritz, Albert Luong, Hakdong Shin, Maria Gloria Dominguez-Bello, Jane M Carlton
In densely populated urban environments, the distribution of microbes and the drivers of microbial community assemblages are not well understood. In sprawling metropolitan habitats, the "urban microbiome" may represent a mix of human-associated and environmental taxa. Here we carried out a baseline study of automated teller machine (ATM) keypads in New York City (NYC). Our goal was to describe the biodiversity and biogeography of both prokaryotic and eukaryotic microbes in an urban setting while assessing the potential source of microbial assemblages on ATM keypads...
November 2016: MSphere
https://www.readbyqxmd.com/read/27903060/satellite-imagery-technology-in-public-health-analysis-of-site-catchment-areas-for-assessment-of-poliovirus-circulation-in-nigeria-and-niger
#10
Marina Takane, Shizu Yabe, Yumiko Tateshita, Yusuke Kobayashi, Akihiko Hino, Kazuo Isono, Hiromasa Okayasu, Ousmane M Diop, Takeo Tadono
Environmental surveillance supplements the surveillance of acute flaccid paralysis by monitoring wastewater for poliovirus circulation. Building on previous work, we analysed wastewater flow to optimise selection and placement of sampling sites with higher digital surface model (DSM) resolution. The newly developed 5-m mesh DSM from the panchromatic, remote-sensing instruments for stereo mapping on-board the Japanese advanced land observing satellite was used to estimate catchment areas and flow of sewage water based on terrain topography...
November 21, 2016: Geospatial Health
https://www.readbyqxmd.com/read/27902350/novel-reassortant-h9n2-viruses-in-pigeons-and-evidence-for-antigenic-diversity-of-h9n2-viruses-isolated-from-quails-in-egypt
#11
Ahmed Kandeil, Rabeh El-Shesheny, Asmaa Maatouq, Yassmin Moatasim, Zhipeng Cai, Pamela McKenzie, Richard Webby, Ghazi Kayali, Mohamed Ahmed Ali
The endemicity of avian influenza viruses (AIVs) among Egyptian poultry represents a public health risk. Co-circulation of low pathogenic AIV H9N2 subtype with highly pathogenic AIV H5N1 subtype in Egyptian farms potentiates the possibility to generate novel reassortant viruses. Herein, the genetic characteristics of surface glycoproteins of 59 Egyptian H9N2 viruses, isolated between 2013 and 2015, were analyzed. To elucidate the potential of genetic reassortment, 10 H9N2 isolates were selected based on different avian hosts (chickens, ducks, pigeons and quails) and conducted for phylogenetic analyses of full genome sequences...
November 11, 2016: Journal of General Virology
https://www.readbyqxmd.com/read/27900188/single-leg-balance-and-core-motor-control-in-children-when-does-the-risk-for-acl-injury-occurs
#12
Allison B Hutchinson, Paul Yao, Mark R Hutchinson
INTRODUCTION: While numerous publications have demonstrated the correlation of poor single-leg balance and core motor control with an increased risk of anterior cruciate ligament (ACL) injuries in skeletally mature female athletes, few have analysed the preadolescent population regarding when indeed comparative deficits in balance and core control actually occur. The purpose of this study was to assess whether the neuromotor factors that place mature females at increased risk of ACL injury actually are present in preadolescents and if so when...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27898721/hepatitis-b-virus-infections-and-associated-factors-among-pregnant-women-attending-antenatal-care-clinic-at-deder-hospital-eastern-ethiopia
#13
Abdi Umare, Berhanu Seyoum, Tesfaye Gobena, Tamirat Haile Mariyam
BACKGROUND: Hepatitis B virus (HBV) infection is a serious public health problem worldwide. Reports have shown that 68,600 people die of HBV infection and more than 300,000 deaths due to liver cancer secondary to hepatitis B every year globally. Women who are infected with HBV can vertically transmit the infection to their infants. This study aims to determine the prevalence of HBV infection and associated factors among pregnant women. METHODS AND FINDINGS: A hospital-based cross-sectional study was conducted among pregnant women who attended antenatal care clinic (ANC) for routine pregnancy check-up between 18 March 2015 and 15 May 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27897136/an-image-based-skeletal-dosimetry-model-for-the-icrp-reference-adult-female-internal-electron-sources
#14
Shannon E O'Reilly, Lindsay S DeWeese, Matthew R Maynard, Didier A Rajon, Michael B Wayson, Emily L Marshall, Wesley E Bolch
An image-based skeletal dosimetry model for internal electron sources was created for the ICRP-defined reference adult female. Many previous skeletal dosimetry models, which are still employed in commonly used internal dosimetry software, do not properly account for electron escape from trabecular spongiosa, electron cross-fire from cortical bone, and the impact of marrow cellularity on active marrow self-irradiation. Furthermore, these existing models do not employ the current ICRP definition of a 50 µm bone endosteum (or shallow marrow)...
December 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27895130/metq-of-neisseria-gonorrhoeae-is-a-surface-expressed-antigen-that-elicits-bactericidal-and-functional-blocking-antibodies
#15
Evgeny A Semchenko, Christopher J Day, Kate L Seib
Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection (STI) gonorrhoea, is a growing public health threat for which a vaccine is urgently needed. We have characterized the functional role of the gonococcal MetQ protein, which is the methionine binding component of an ABC transporter system, and assessed its potential as a candidate antigen for inclusion in a gonococcal vaccine. MetQ is highly conserved in all strains investigated to date, it is localized on the bacterial surface, and it binds L-methionine with high affinity...
November 28, 2016: Infection and Immunity
https://www.readbyqxmd.com/read/27892531/a-genome-wide-association-study-identifies-a-horizontally-transferred-bacterial-surface-adhesin-gene-associated-with-antimicrobial-resistant-strains
#16
Masato Suzuki, Keigo Shibayama, Koji Yahara
Carbapenems are a class of last-resort antibiotics; thus, the increase in bacterial carbapenem-resistance is a serious public health threat. Acinetobacter baumannii is one of the microorganisms that can acquire carbapenem-resistance; it causes severe nosocomial infection, and is notoriously difficult to control in hospitals. Recently, a machine-learning approach was first used to analyze the genome sequences of hundreds of susceptible and resistant A. baumannii strains, including those carrying commonly acquired resistant mechanisms, to build a classifier that can predict strain resistance...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27891360/why-should-viral-markers-be-mandatory-in-ocular-surgeries-a-hospital-based-retrospective-study
#17
Anita Ambastha, Rakhi Kusumesh, Gyan Bhasker
INTRODUCTION: Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus I, II (HIV-I,II) are serious global and public health problem. Knowledge of the seroprevalence would enable early diagnosis, treatment of patients and also help in prevention of horizontal spread of infection by application of universal infection control measures. AIM: To determine the seroprevalence of HBV, HCV and HIV I, II infection in patients undergoing ocular surgery...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891087/a-monte-carlo-evaluation-of-weighted-community-detection-algorithms
#18
Kathleen M Gates, Teague Henry, Doug Steinley, Damien A Fair
The past decade has been marked with a proliferation of community detection algorithms that aim to organize nodes (e.g., individuals, brain regions, variables) into modular structures that indicate subgroups, clusters, or communities. Motivated by the emergence of big data across many fields of inquiry, these methodological developments have primarily focused on the detection of communities of nodes from matrices that are very large. However, it remains unknown if the algorithms can reliably detect communities in smaller graph sizes (i...
2016: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/27890622/multi-functional-nanoparticles-as-theranostic-agents-for-treatment-imaging-in-pancreatic-cancer
#19
L R Jaidev, David Raj Chellappan, Dhiraj Vasanth Bhavsar, Ravi Ranganathan, Banudevi Sivanantham, Anuradha Subramanian, Uma Sharma, Narnamangalam R Jagannathan, Uma Maheswari Krishnan, Swaminathan Sethuraman
: Theranostics has received considerable attention since both therapy and imaging modalities can be integrated into a single nanocarrier. In this study, fluorescent iron oxide (FIO) nanoparticles and gemcitabine (G) encapsulated poly(lactide-co-glycolide) (PLGA) nanospheres (PGFIO) conjugated with human epidermal growth factor receptor 2, (HER-2) antibody (HER-PGFIO) were prepared and characterized. HER-PGFIO showed the magnetic moment of 10 emu/g, relaxivity (r2) of 773 mM(-1)s(-1) and specific absorption rate (SAR) of 183 W/g...
November 23, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27890403/isoelectric-points-and-points-of-zero-charge-of-metal-hydr-oxides-50years-after-parks-review
#20
REVIEW
Marek Kosmulski
The pH-dependent surface charging of metal (hydr)oxides is reviewed on the occasion of the 50th anniversary of the publication by G.A. Parks: "Isoelectric points of solid oxides, solid hydroxides, and aqueous hydroxo complex systems" in Chemical Reviews. The point of zero charge (PZC) and isoelectric point (IEP) became standard parameters to characterize metal oxides in aqueous dispersions, and they define adsorption (surface excess) of ions, stability against coagulation, rheological properties of dispersions, etc...
November 5, 2016: Advances in Colloid and Interface Science
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