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https://www.readbyqxmd.com/read/28798972/diagnostic-precision-of-triage-algorithms-for-mass-casualty-incidents-english-version
#1
A R Heller, N Salvador, M Frank, J Schiffner, R Kipke, C Kleber
BACKGROUND: Regarding survival and quality of life recent mass casualty incidents again emphasize the importance of early identification of the correct degree of injury/illness to enable prioritization of treatment amongst patients and their transportation to an appropriate hospital. The present study investigated existing triage algorithms in terms of sensitivity (SE) and specificity (SP) as well as its process duration in a relevant emergency patient cohort. METHODS: In this study 500 consecutive air rescue missions were evaluated by means of standardized patient records...
August 10, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28783081/culturing-toxic-benthic-blooms-the-fate-of-natural-biofilms-in-a-microcosm-system
#2
Francesca Di Pippo, Roberta Congestri
A microcosm designed for culturing aquatic phototrophic biofilms on artificial substrata was used to perform experiments with microphytobenthos sampled during summer toxic outbreaks of Ostreopsis cf. ovata along the Middle Tyrrhenian coast. This dynamic approach aimed at exploring the unique and complex nature of O. cf. ovata bloom development in the benthic system. Epibenthic assemblages were used as inocula for co-cultures of bloom organisms on polycarbonate slides at controlled environmental conditions. Biofilm surface adhesion, growth, and spatial structure were evaluated along with shifts in composition and matrix production in a low disturbance regime, simulating source habitat...
August 6, 2017: Microorganisms
https://www.readbyqxmd.com/read/28776045/whole-genome-sequencing-of-human-clinical-klebsiella-pneumoniae-isolates-reveals-misidentification-and-misunderstandings-of-klebsiella-pneumoniae-klebsiella-variicola-and-klebsiella-quasipneumoniae
#3
S Wesley Long, Sarah E Linson, Matthew Ojeda Saavedra, Concepcion Cantu, James J Davis, Thomas Brettin, Randall J Olsen
Klebsiella pneumoniae is a major threat to public health, causing significant morbidity and mortality worldwide. The emergence of highly drug-resistant strains is particularly concerning. There has been a recognition and division of Klebsiella pneumoniae into three distinct phylogenetic groups: Klebsiella pneumoniae, Klebsiella variicola, and Klebsiella quasipneumoniae. K. variicola and K. quasipneumoniae have often been described as opportunistic pathogens that have less virulence in humans than K. pneumoniae does...
July 2017: MSphere
https://www.readbyqxmd.com/read/28772873/a-new-energy-critical-plane-damage-parameter-for-multiaxial-fatigue-life-prediction-of-turbine-blades
#4
Zheng-Yong Yu, Shun-Peng Zhu, Qiang Liu, Yunhan Liu
As one of fracture critical components of an aircraft engine, accurate life prediction of a turbine blade to disk attachment is significant for ensuring the engine structural integrity and reliability. Fatigue failure of a turbine blade is often caused under multiaxial cyclic loadings at high temperatures. In this paper, considering different failure types, a new energy-critical plane damage parameter is proposed for multiaxial fatigue life prediction, and no extra fitted material constants will be needed for practical applications...
May 8, 2017: Materials
https://www.readbyqxmd.com/read/28744481/visualizing-antimicrobials-in-bacterial-biofilms-three-dimensional-biochemical-imaging-using-tof-sims
#5
Sarah K Davies, Sarah Fearn, Luke P Allsopp, Freya Harrison, Ecaterina Ware, Stephen P Diggle, Alain Filloux, David S McPhail, Jacob G Bundy
Bacterial biofilms are groups of bacteria that exist within a self-produced extracellular matrix, adhering to each other and usually to a surface. They grow on medical equipment and inserts such as catheters and are responsible for many persistent infections throughout the body, as they can have high resistance to many antimicrobials. Pseudomonas aeruginosa is an opportunistic pathogen that can cause both acute and chronic infections and is used as a model for research into biofilms. Direct biochemical methods of imaging of molecules in bacterial biofilms are of high value in gaining a better understanding of the fundamental biology of biofilms and biochemical gradients within them...
July 2017: MSphere
https://www.readbyqxmd.com/read/28710994/toxic-compounds-from-tobacco-in-placenta-samples-analyzed-by-uplc-qtof-ms
#6
Somayeh Mohammadi, Celia Domeno, Isabel Nerin, Margarita Aznar, Pilar Samper, Gholamreza Khayatian, Cristina Nerin
Polycyclic aromatic hydrocarbons (PAHs), tobacco-specific nitrosamines (TSNAs) and aromatic amines are carcinogens present in cigarette smoke. These compounds are distributed in the human body and they could be transferred to the foetus during the pregnancy. Placenta is the main barrier to these toxic compounds and its study is the objective of this work. A method based on solid-phase extraction (SPE) with ultra-performance liquid chromatography-tandem quadrupole-time-of-flight mass spectrometry (UPLC-QTOF-MS) has been examined and optimized for the analysis of 9 target analytes (4 tobacco-specific nitrosamines and some of their metabolites, 3 aromatic amines, nicotine and cotinine) in 26 placenta samples from smoking and non-smoking women...
June 20, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28701789/mental-workload-and-neural-efficiency-quantified-in-the-prefrontal-cortex-using-fnirs
#7
Mickaël Causse, Zarrin Chua, Vsevolod Peysakhovich, Natalia Del Campo, Nadine Matton
An improved understanding of how the brain allocates mental resources as a function of task difficulty is critical for enhancing human performance. Functional near infrared spectroscopy (fNIRS) is a field-deployable optical brain monitoring technology that provides a direct measure of cerebral blood flow in response to cognitive activity. We found that fNIRS was sensitive to variations in task difficulty in both real-life (flight simulator) and laboratory settings (tests measuring executive functions), showing increased concentration of oxygenated hemoglobin (HbO2) and decreased concentration of deoxygenated hemoglobin (HHb) in the prefrontal cortex as the tasks became more complex...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28666311/fully-automatic-and-precise-data-analysis-developed-for-time-of-flight-mass-spectrometry
#8
S Meyer, A Riedo, M B Neuland, M Tulej, P Wurz
Scientific objectives of current and future space missions are focused on the investigation of the origin and evolution of the solar system with the particular emphasis on habitability and signatures of past and present life. For in situ measurements of the chemical composition of solid samples on planetary surfaces, the neutral atmospheric gas, and the thermal plasma of planetary atmospheres, the application of mass spectrometers making use of time-of-flight mass analysers is a technique widely used. However, such investigations imply measurements with good statistics and thus, a large amount of data to be analysed...
June 30, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28665327/green-mind-theory-how-brain-body-behaviour-links-into-natural-and-social-environments-for-healthy-habits
#9
Jules Pretty, Mike Rogerson, Jo Barton
We propose a Green Mind Theory (GMT) to link the human mind with the brain and body, and connect the body into natural and social environments. The processes are reciprocal: environments shape bodies, brains, and minds; minds change body behaviours that shape the external environment. GMT offers routes to improved individual well-being whilst building towards greener economies. It builds upon research on green exercise and nature-based therapies, and draws on understanding derived from neuroscience and brain plasticity, spiritual and wisdom traditions, the lifeways of original cultures, and material consumption behaviours...
June 30, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28662566/ontogeny-of-flight-capacity-and-pectoralis-function-in-a-precocial-ground-bird-alectoris-chukar
#10
Bret W Tobalske, Brandon E Jackson, Kenneth P Dial
Flight is the defining characteristic of birds, yet the mechanisms through which flight ability develops are only beginning to be understood. Wing-assisted incline running (WAIR) and controlled flapping descent (CFD) are behaviors that may offer significant adaptive benefits to developing birds. Recent research into these forms of locomotion has focused on species with precocial development, with a particularly rich data set from chukar partridge (Alectoris chukar). Here we briefly review the kinematics and aerodynamics of flight development in this species...
June 28, 2017: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/28662066/mitochondrial-dna-markers-reveal-high-genetic-diversity-and-strong-genetic-differentiation-in-populations-of-dendrolimus-kikuchii-matsumura-lepidoptera-lasiocampidae
#11
Qiulei Men, Guoxi Xue, Dan Mu, Qingling Hu, Minyi Huang
Dendrolimus kikuchii Matsumura, 1927 is a serious forest pest causing great damage to coniferous trees in China. Despite its economic importance, the population genetics of this pest are poorly known. We used three mitochondrial genes (COI, COII and Cytb) to investigate the genetic diversity and genetic differentiation of 15 populations collected from the main distribution regions of D. kikuchii in China. Populations show high haplotype and nucleotide diversity. Haplotype network and phylogenetic analysis divides the populations into three major clades, the central and southeastern China (CC+SEC) clade, the eastern China (EC) clade, and the southwestern China (SWC) clade...
2017: PloS One
https://www.readbyqxmd.com/read/28655496/mosquito-aging-modulates-the-heart-rate-and-the-proportional-directionality-of-heart-contractions
#12
Charlotte R Doran, Tania Y Estévez-Lao, Julián F Hillyer
Mosquito aging impacts a myriad of physiological processes, including digestion, flight, mating, reproductive success, and immunity. In the present study, we conducted intravital video imaging in 1, 3, 5, 10, 15 and 20-day-old Anopheles gambiae female adults to assess whether aging impacts mosquito heart physiology. We found that the heart contraction rate increases over the first 15days of adulthood and then decreases. These changes occur for both contraction directions, although aging results in a relative change in the anterograde versus retrograde contraction rates...
June 24, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28642430/avian-egg-shape-form-function-and-evolution
#13
Mary Caswell Stoddard, Ee Hou Yong, Derya Akkaynak, Catherine Sheard, Joseph A Tobias, L Mahadevan
Avian egg shape is generally explained as an adaptation to life history, yet we currently lack a global synthesis of how egg-shape differences arise and evolve. Here, we apply morphometric, mechanistic, and macroevolutionary analyses to the egg shapes of 1400 bird species. We characterize egg-shape diversity in terms of two biologically relevant variables, asymmetry and ellipticity, allowing us to quantify the observed morphologies in a two-dimensional morphospace. We then propose a simple mechanical model that explains the observed egg-shape diversity based on geometric and material properties of the egg membrane...
June 23, 2017: Science
https://www.readbyqxmd.com/read/28636611/unmanned-aircraft-systems-as-a-new-source-of-disturbance-for-wildlife-a-systematic-review
#14
Margarita Mulero-Pázmány, Susanne Jenni-Eiermann, Nicolas Strebel, Thomas Sattler, Juan José Negro, Zulima Tablado
The use of small Unmanned Aircraft Systems (UAS; also known as "drones") for professional and personal-leisure use is increasing enormously. UAS operate at low altitudes (<500 m) and in any terrain, thus they are susceptible to interact with local fauna, generating a new type of anthropogenic disturbance that has not been systematically evaluated. To address this gap, we performed a review of the existent literature about animals' responses to UAS flights and conducted a pooled analysis of the data to determine the probability and intensity of the disturbance, and to identify the factors influencing animals' reactions towards the small aircraft...
2017: PloS One
https://www.readbyqxmd.com/read/28630743/comparison-of-five-video-assisted-intubation-devices-by-novice-and-expert-laryngoscopists-for-use-in-the-aeromedical-evacuation-environment
#15
Matthew C Wallace, SSgt Tyler Britton, Robbie Meek, Sharon Walsh-Hart, Col Todd E Carter, Steven J Lisco
BACKGROUND: The critically ill or injured patient undergoing military medical evacuation may require emergent intubation. Intubation may be life-saving, but it carries risks. The novice or infrequent laryngoscopist has a distinct disadvantage because experience is critical for the rapid and safe establishment of a secured airway. This challenge is compounded by the austere environment of the back of an aircraft under blackout conditions. This study determined which of five different video-assisted intubation devices (VAIDs) was best suited for in-flight use by U...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28630012/assessing-passeriformes-health-in-south-texas-via-select-venous-analytes
#16
J Pistone, J J Heatley, T A Campbell, G Voelker
The handheld point of care analyzer is a quick and feasible option to obtain hematology data from individuals. The iSTAT-1® was used to evaluate select venous blood analytes obtained via jugular venipuncture from 238 passerine birds from South Texas. These data were used to assess the health of birds in the area while taking into consideration life history (migratory or sedentary), locale, seasonality, sex, and age. We attributed increased values of pO2 and hematocrit, in addition to hemoglobin and glucose concentrations of migratory birds compared to sedentary birds as the increased need of oxygen carrying capacity and energy for long duration flights...
August 2017: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28618194/sexual-dimorphism-in-the-alpine-butterflies-boloria-pales-and-boloria-napaea-differences-in-movement-and-foraging-behaviour-lepidoptera-nymphalidae
#17
Stefan Ehl, Katharina Hostert, Jana Korsch, Patrick Gros, Thomas Schmitt
Sexual dimorphism is a widespread phenomenon in Lepidoptera. It is reflected in differences in life history, behaviour and morphology. Analyses of differences in behaviour are mostly difficult and time-consuming, especially in high mountain ecosystems. To enhance our knowledge on sexual dimorphisms of alpine butterflies, we performed a mark-release-recapture study on two species common in the Alps: Boloria pales and Boloria napaea. We analysed movement and foraging behaviour to investigate differences between sexes...
June 15, 2017: Insect Science
https://www.readbyqxmd.com/read/28612235/bio-logging-new-technologies-to-study-conservation-physiology-on-the-move-a-case-study-on-annual-survival-of-himalayan-vultures
#18
Sherub Sherub, Wolfgang Fiedler, Olivier Duriez, Martin Wikelski
Bio-logging, the on-animal deployment of miniaturised electronic data recorders, allows for the study of location, body position, and physiology of individuals throughout their ontogeny. For terrestrial animals, 1 Hz GPS-position, 3D-body acceleration, and ambient temperature provide standard data to link to the physiology of life histories. Environmental context is added at ever finer scales using remote sensing earth observation data. Here we showcase the use of such bio-logging approaches in a conservation physiology study on endangered Himalayan vultures (Gyps himalayensis)...
July 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28582768/investigation-on-the-influence-of-time-of-day-on-benzene-metabolic-pharmacokinetics-by-direct-breath-analysis-in-mice
#19
Yuling Zhang, Wanyang Sun, Dewei Shang, Hao Gao, Zhen Zhou, Xue Li
Benzene, well known as a ubiquitous environmental pollutant, can lead to increasing risk of cancer, bone marrow failure as well as other serious diseases. Benzene has been classified as carcinogenic to humans with no recommended safe level of exposure. In this study, the influence of time-of-day on benzene metabolism has been tentatively explored in a mouse model based on direct real-time breath analysis by using membrane inlet single photon ionization time of flight mass spectrometry (MI-SPI-TOFMS). The exhaled breath of eight mice was monitored at a time resolution of less than 20 s after intraperitoneal (I...
October 2017: Chemosphere
https://www.readbyqxmd.com/read/28549311/reaction-of-diazepam-and-related-benzodiazepines-with-chlorine-kinetics-transformation-products-and-in-silico-toxicological-assessment
#20
Inmaculada Carpinteiro, Rosario Rodil, José Benito Quintana, Rafael Cela
In this work, the reaction of four benzodiazepines (diazepam, oxazepam, nordazepam and temazepam) during water chlorination was studied by means of liquid chromatography-quadrupole-time of flight-mass spectrometry (LC-QTOF-MS). For those compounds that showed a significant degradation, i.e. diazepam, oxazepam and nordazepam, parameters affecting to the reaction kinetics (pH, chlorine and bromide level) were studied in detail and transformation products were tentatively identified. The oxidation reactions followed pseudofirst-order kinetics with rate constants in the range of 1...
May 3, 2017: Water Research
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