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https://www.readbyqxmd.com/read/27917504/constructing-and-enacting-kinship-in-sister-to-sister-egg-donation-families-a-multi-family-member-interview-study
#1
Hanna Van Parys, Veerle Provoost, Kristin Zeiler, Petra De Sutter, Guido Pennings, Ann Buysse
Although intra-familial egg donation has been practiced for more than 15 years in several countries, little is known about family relationships in this family type. Framed within the new kinship studies, this article focuses on the experiential dimension of kinship in sister-to-sister egg donation families: how is kinship 'unpacked' and 'reconstructed' in this specific family constellation? Qualitative data analysis of interviews with receiving parents, their donating sisters and the donor children revealed six themes: (1) being connected as an extended family; (2) disambiguating motherhood; (3) giving and receiving as structuring processes; (4) acknowledging and managing the 'special' link between donor and child; (5) making sense of the union between father and donor; and (6) kinship constructions being challenged...
December 5, 2016: Sociology of Health & Illness
https://www.readbyqxmd.com/read/27872720/a-comparative-study-on-the-effects-of-different-cryoprotectants-on-the-quality-of-canine-sperm-during-vitrification-process
#2
Sahar Nouri Gharajelar, Rajab Ali Sadrkhanloo, Masoud Onsori, Adel Saberivand
Cryopreservation has the capacity to extend spermatozoa's lifespan and viability. In addition, the semen samples can be collected, preserved and stored or sent to distant locations and still be used long after the death of the semen donor. In this study for the vitrification of dog sperm (fresh and swum-up sperm), different cryopreservation mediums on the basis of glycerol, milk and egg yolk were used. Then, all of the samples were vitrified in the liquid nitrogen and thawed at least 48 hr later for re-examination of sperm parameters...
2016: Veterinary Research Forum
https://www.readbyqxmd.com/read/27853913/differences-in-pregnancy-outcomes-in-donor-egg-frozen-embryo-transfer-fet-cycles-following-preimplantation-genetic-screening-pgs-a-single-center-retrospective-study
#3
Alison Coates, Brandon J Bankowski, Allen Kung, Darren K Griffin, Santiago Munne
PURPOSE: This study aims to test the hypothesis, in a single-center retrospective analysis, that live birth rates are significantly different when utilizing preimplantation genetic screening (PGS) compared to not utilizing PGS in frozen-thawed embryo transfers in our patients that use eggs from young, anonymous donors. The question therefore arises of whether PGS is an appropriate intervention for donor egg cycles. METHODS: Live birth rates per cycle and live birth rates per embryo transferred after 398 frozen embryo transfer (FET) cycles were examined from patients who elected to have PGS compared to those who did not...
November 16, 2016: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/27825378/buying-and-selling-human-eggs-infertility-providers-ethical-and-other-concerns-regarding-egg-donor-agencies
#4
Robert Klitzman
BACKGROUND: Egg donor agencies are increasingly being used as part of IVF in the US, but are essentially unregulated, posing critical ethical and policy questions concerning how providers view and use them, and what the implications might be. METHODS: Thirty-seven in-depth interviews of approximately 1 h were conducted - with 27 IVF providers and 10 patients. RESULTS: Clinicians vary in their views and interactions concerning egg donor agencies, ranging widely in whether and how often they use agencies...
November 8, 2016: BMC Medical Ethics
https://www.readbyqxmd.com/read/27822908/the-duration-of-gonadotropin-stimulation-does-not-alter-the-clinical-pregnancy-rate-in-ivf-or-icsi-cycles
#5
N Purandare, G Emerson, C Kirkham, C Harrity, D Walsh, E Mocanu
BACKGROUND: Ovarian stimulation is an essential part of assisted reproduction treatments. Research on whether the duration of stimulation alters the success in assisted reproduction has not been conclusive. AIM: The purpose of the study was to establish whether the duration of ovarian stimulation alters the success in assisted reproduction treatments. METHODS: All fresh (non-donor) stimulation cycles performed in an academic tertiary referral ART centre over a period of 18 years, between 1st January 1997 and 31st December 2014, were identified...
November 7, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27822347/acceptance-and-disclosure-comparing-genetic-symmetry-and-genetic-asymmetry-in-heterosexual-couples-between-egg-recipients-and-embryo-recipients
#6
R Hertz, M K Nelson
This paper explores the attitudes and experiences of 203 women in heterosexual couples who conceived via donated eggs (145) or donated embryos (58) in the last 5 years. Online surveys were sent to former patients (from many different countries) of a private Spanish clinic. By comparing the women in heterosexual couples who relied on donated eggs with those who relied on donated embryos, we examined the meaning of the absence of a genetic tie to a child in the two different situations - that of "genetic symmetry" where neither parent has a genetic tie to that of "genetic asymmetry" where only the mother does not have a genetic tie...
March 28, 2016: Facts, Views & Vision in ObGyn
https://www.readbyqxmd.com/read/27820604/influenza-immunization-elicits-antibodies-specific-for-an-egg-adapted-vaccine-strain
#7
Donald D Raymond, Shaun M Stewart, Jiwon Lee, Jack Ferdman, Goran Bajic, Khoi T Do, Michael J Ernandes, Pirada Suphaphiphat, Ethan C Settembre, Philip R Dormitzer, Giuseppe Del Giudice, Oretta Finco, Tae Hyun Kang, Gregory C Ippolito, George Georgiou, Thomas B Kepler, Barton F Haynes, M Anthony Moody, Hua-Xin Liao, Aaron G Schmidt, Stephen C Harrison
For broad protection against infection by viruses such as influenza or HIV, vaccines should elicit antibodies that bind conserved viral epitopes, such as the receptor-binding site (RBS). RBS-directed antibodies have been described for both HIV and influenza virus, and the design of immunogens to elicit them is a goal of vaccine research in both fields. Residues in the RBS of influenza virus hemagglutinin (HA) determine a preference for the avian or human receptor, α-2,3-linked sialic acid and α-2,6-linked sialic acid, respectively...
December 2016: Nature Medicine
https://www.readbyqxmd.com/read/27819301/talen-mediated-knock-in-via-non-homologous-end-joining-in-the-crustacean-daphnia-magna
#8
Takashi Nakanishi, Yasuhiko Kato, Tomoaki Matsuura, Hajime Watanabe
Transcription activator-like effector nucleases (TALENs) are versatile tools that enable the insertion of DNA into different organisms. Here, we confirmed TALEN-mediated knock-in via non-homologous end joining in the crustacean Daphnia magna, a model organism for ecological and toxicological genomics. We tested two different TALENs, ey1 TALEN and ey2 TALEN, both of which target the eyeless locus. The donor DNA plasmid, harbouring the H2B-GFP reporter gene, was designed to contain both TALEN target sites and was co-injected with each TALEN mRNA into eggs...
November 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27795455/blood-soy-milk-and-vitality-the-wartime-origins-of-blood-banking-in-china-1943-45
#9
Wayne Soon
This article examines the multiple meanings of blood transfusion and banking in modern China through the history of the first Chinese blood bank, established by the Overseas Chinese in 1943 to solicit blood for the war effort. Through investigating the attitudes of Chinese soldiers and civilians toward the blood bank, this article argues for the multiplicity of motivations underpinning society's attitudes toward blood banking and donation. Cultural notions of blood were an important but not the sole factor in their consideration...
2016: Bulletin of the History of Medicine
https://www.readbyqxmd.com/read/27789184/a-limited-survey-based-uncontrolled-follow-up-study-of-children-born-after-ooplasmic-transplantation-in-a-single-centre
#10
Serena H Chen, Claudia Pascale, Maria Jackson, Mary Ann Szvetecz, Jacques Cohen
Experimental ooplasmic transplantation from donor to recipient oocyte took place between 1996 and 2001 at Saint Barnabas Medical Center, USA. Indication for 33 patients was repeated implantation failure. Thirteen couples had 17 babies. One patient delivered twins from mixed ooplasmic and donor egg embryos. A limited survey-based follow-up study on the children is reported: 12 out of 13 parents completed a questionnaire on pregnancy, birth, health, academic performance and disclosure. Parents of a quadruplet did not participate...
October 24, 2016: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/27774232/gamete-donor-anonymity-and-limits-on-numbers-of-offspring-the-views-of-three-stakeholders
#11
Margaret K Nelson, Rosanna Hertz, Wendy Kramer
This paper discusses the attitudes of three groups of stakeholders in the world of assisted reproduction gamete donors, parents who use donated gamete, and offspring conceived with donated gametes with respect to the two issues of donor anonymity and limits on the number of offspring a single donor can produce. The data are drawn from on-line surveys which were made available between May 12, 2104 and August 15, 2014 to gamete donors, donor-conceived offspring, and parents who used donated gametes to conceive...
April 2016: Journal of Law and the Biosciences
https://www.readbyqxmd.com/read/27716543/deficiency-in-memory-b-cell-compartment-in-a-patient-with-infertility-and-recurrent-pregnancy-losses
#12
N Sung, H J Byeon, M D Salazar Garcia, A Skariah, L Wu, S Dambaeva, K Beaman, A Gilman-Sachs, J Kwak-Kim
Alterations in normal balance of B cell subsets have been reported in various rheumatic diseases. In this study, we report a woman with a history of recurrent pregnancy losses (RPL) and infertility who had low levels of memory B cells. A 35-year-old woman with a history of RPL and infertility was demonstrated to have increased peripheral blood CD19+ B cells with persistently low levels of memory B cell subsets. Prior to the frozen donor egg transfer cycle, prednisone and intravenous immunoglobulin G (IVIg) treatment was initiated and patient achieved dichorionic diamniotic twin pregnancies...
September 28, 2016: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/27701050/s-nitroso-n-acetyl-penicillamine-inhibits-spontaneous-exit-from-metaphase-ii-arrest-in-rat-eggs-cultured-in-vitro
#13
Shilpa Prasad, Shail K Chaube
BACKGROUND: Present study was designed to investigate the in vitro effects of nitric oxide (NO) donor such as S-nitroso-N-acetyl penicillamine (SNAP) on spontaneous exit from metaphase-II arrest (SEM-II) in rat eggs cultured in vitro. METHODS: Ovulated eggs were denuded and then exposed to various concentrations (0.0, 0.01, 0.1 and 1.0mM) of SNAP for 3h under in vitro culture conditions. The percentage of SEM-II, specific and total phosphorylated cyclin-dependent kinase-1 (Cdk1), cyclin B1 and anaphase promoting complex/cyclosome (APC/C) levels as well as Cdk1 activity were analyzed...
October 1, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27581197/generation-of-juvenile-rainbow-trout-derived-from-cryopreserved-whole-ovaries-by-intraperitoneal-transplantation-of-ovarian-germ-cells
#14
Seungki Lee, Naoto Katayama, Goro Yoshizaki
Cryopreservation of fish sperm offers the practical applications in the selective breeding and biodiversity conservation. However, because of the lack of cryopreservation methods for fish eggs and embryos, maternally inherited cytoplasmic compartments cannot be successfully preserved. We previously developed an alternative method to derive functional eggs and sperm from cryopreserved whole testis by transplanting testicular cells into female and male recipients. However, if target fish had ovaries, the previous method employing male-derived germ cells would be ineffective...
September 23, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27565261/gay-father-surrogacy-families-relationships-with-surrogates-and-egg-donors-and-parental-disclosure-of-children-s-origins
#15
Lucy Blake, Nicola Carone, Jenna Slutsky, Elizabeth Raffanello, Anke A Ehrhardt, Susan Golombok
OBJECTIVE: To study the nature and quality of relationships between gay father families and their surrogates and egg donors and parental disclosure of children's origins. DESIGN: Cross-sectional study. SETTING: Family homes. PATIENT(S): Parents in 40 gay father families with 3-9-year-old children born through surrogacy. INTERVENTION(S): Administration of a semistructured interview. MAIN OUTCOME MEASURE(S): Relationships between parents, children, surrogates, and egg donors and parental disclosure of children's origins were examined using a semistructured interview...
August 23, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27563721/being-an-identity-release-donor-a-qualitative-study-exploring-the-motivations-experiences-and-future-expectations-of-current-uk-egg-donors
#16
Susanna Graham, Vasanti Jadva, Tabitha Freeman, Kamal Ahuja, Susan Golombok
The objective of this study was to examine the motivations, experiences and future expectations of identity-release egg donors in the UK following the removal of donor anonymity and the increase in financial compensation for egg donation. This exploratory, in-depth qualitative study comprised semi-structured interviews with 11 women who had attended an egg donation screening appointment at a UK clinic during a four-month period in 2014. Interviews were conducted two to six weeks after the woman had donated or had withdrawn/been rejected from the donation process...
August 26, 2016: Human Fertility: Journal of the British Fertility Society
https://www.readbyqxmd.com/read/27553622/different-effectiveness-of-closed-embryo-culture-system-with-time-lapse-imaging-embryoscope-tm-in-comparison-to-standard-manual-embryology-in-good-and-poor-prognosis-patients-a-prospectively-randomized-pilot-study
#17
Yan-Guang Wu, Emanuela Lazzaroni-Tealdi, Qi Wang, Lin Zhang, David H Barad, Vitaly A Kushnir, Sarah K Darmon, David F Albertini, Norbert Gleicher
BACKGROUND: Previously manual human embryology in many in vitro fertilization (IVF) centers is rapidly being replaced by closed embryo incubation systems with time-lapse imaging. Whether such systems perform comparably to manual embryology in different IVF patient populations has, however, never before been investigated. We, therefore, prospectively compared embryo quality following closed system culture with time-lapse photography (EmbryoScope™) and standard embryology. We performed a two-part prospectively randomized study in IVF (clinical trial # NCT92256309)...
August 24, 2016: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/27542392/fatal-ovarian-hyperstimulation-syndrome-in-an-anonymous-egg-donor
#18
Shashank Pooniya, C Behera, A R Mridha, D N Bhardwaj, Tabin Millo
Ovarian hyperstimulation syndrome is a rare, but potentially life-threatening iatrogenic disorder arising from ovulation induction or ovarian hyperstimulation for assisted reproduction techniques. We report a case of a 26-year-old multiparous woman, an anonymous egg donor, who died a few hours after undergoing a procedure to donate eggs at an in vitro fertilization clinic. Her husband alleged that medical negligence had led to her death. The autopsy confirmed death due to ovarian hyperstimulation syndrome...
August 19, 2016: Medico-legal Journal
https://www.readbyqxmd.com/read/27496943/assisted-reproductive-technology-in-europe-2012-results-generated-from-european-registers-by-eshre
#19
C Calhaz-Jorge, C de Geyter, M S Kupka, J de Mouzon, K Erb, E Mocanu, T Motrenko, G Scaravelli, C Wyns, V Goossens
STUDY QUESTION: The 16th European IVF-monitoring (EIM) report presents the data of the treatments involving assisted reproductive technology (ART) and intrauterine insemination (IUI) initiated in Europe during 2012: are there any changes compared with previous years? SUMMARY ANSWER: Despite some fluctuations in the number of countries reporting data, the overall number of ART cycles has continued to increase year by year, the pregnancy rates (PRs) in 2012 remained stable compared with those reported in 2011, and the number of transfers with multiple embryos (3+) and the multiple delivery rates were lower than ever before...
August 2016: Human Reproduction
https://www.readbyqxmd.com/read/27496280/long-term-5-years-cryopreserved-spermatogonia-have-high-capacity-to-generate-functional-gametes-via-interspecies-transplantation-in-salmonids
#20
Seungki Lee, Yoshiko Iwasaki, Goro Yoshizaki
Although sperm cryopreservation is a powerful tool widely applicable in biodiversity conservation and broodstock management, cryopreservation of teleost eggs and embryos remains challenging. In the present study, we demonstrated that spermatogonia of rainbow trout (Oncorhynchus mykiss) cryopreserved for 5 years possessed the ability to differentiate into functional eggs or sperm in the gonads of triploid recipient masu salmon (Oncorhynchus masou). After cryopreservation for 5 years in liquid nitrogen, intraperitoneally transplanted spermatogonia migrated toward, and incorporated into, the gonads of xenogeneic recipients...
October 2016: Cryobiology
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