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Oocyte donation

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https://www.readbyqxmd.com/read/28921586/down-syndrome-maternal-serum-markers-in-oocyte-donation-and-other-assisted-reproductive-technologies
#1
Aurore Bonnin, Françoise Muller, Marie-Victoire Senat, Corinne Sault, Armelle Galland, Joëlle Taieb, Sophie Dreux, Jean Bouyer, Alexandra Benachi
OBJECTIVE: Because maternal serum markers (PAPP-A, hCGβ, and AFP) used for Down syndrome (DS) screening have been described as predictors of obstetrical complications and because assisted reproductive technology (ART) pregnancies are known to be at increased risk for obstetrical complications, it is unclear whether or not correction factors should be applied to the calculated risk of DS. The purpose of this study was to evaluate DS maternal serum markers in oocyte donation (OD) and ART pregnancies in comparison with natural pregnancies...
September 16, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28916332/assessing-the-use-of-assisted-reproductive-technology-in-the-united-states-by-non-united-states-residents
#2
Aaron D Levine, Sheree L Boulet, Roberta M Berry, Denise J Jamieson, Hillary B Alberta-Sherer, Dmitry M Kissin
OBJECTIVE: To study cross-border reproductive care (CBRC) by assessing the frequency and nature of assisted reproductive technology (ART) care that non-U.S. residents receive in the United States. DESIGN: Retrospective study of ART cycles reported to the Centers for Disease Control and Prevention's National ART Surveillance System (NASS) from 2006 to 2013. SETTING: Private and academic ART clinics. PATIENT(S): Patients who participated in ART cycles in the United States from 2006 to 2013...
August 31, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28890894/risk-of-contamination-of-gametes-and-embryos-during-cryopreservation-and-measures-to-prevent-cross-contamination
#3
REVIEW
Daniel C Joaquim, Eduardo D Borges, Iara G R Viana, Paula A Navarro, Alessandra A Vireque
The introduction and widespread application of vitrification are one of the most important achievements in human assisted reproduction techniques (ART) of the past decade despite controversy and unclarified issues, mostly related to concerns about disease transmission. Guidance documents published by US Food and Drug Administration, which focused on the safety of tissue/organ donations during Zika virus spread in 2016, as well as some reports of virus, bacteria, and fungi survival to cryogenic temperatures, highlighted the need for a review of the way how potentially infectious material is handled and stored in ART-related procedures...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28882430/reproductive-outcomes-in-recipients-are-not-associated-with-oocyte-donor-body-mass-index-up-to-28%C3%A2-kg-m-2-a-cohort-study-of-2722-cycles
#4
Francisca Martínez, Alejandro Kava-Braverman, Elisabet Clúa, Ignacio Rodríguez, Sofia Gaggiotti Marre, Buenaventura Coroleu, Pedro N Barri
The effect of increasing donor body mass index (BMI) on clinical pregnancies was retrospectively analysed in a cohort of consecutive 2722 donor oocyte IVF cycles. The relationship between donor BMI and clinical pregnancies was assessed after adjusting for recipient BMI. Clinical pregnancy rates and live birth rates (LBR) were no different with increasing donor BMI (up to donor BMI ≤28 kg/m(2)). The odds of pregnancy did not vary with donor BMI. Compared with donor BMI quartile 1, OR 95% CI of clinical pregnancy was 1...
August 15, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28869028/-the-use-of-anti-m%C3%A3-llerian-hormone-in-fertility-treatment
#5
Fie Pilsgaard, Anna Garcia-Alix Grynnerup, Kristine Løssl, Anja Pinborg
The need for fertility treatment in Denmark is increasing, one of the main causes being postponed parenthood. Ovarian reserve is determined by the anti-Müllerian hormone (AMH) level and by antral follicle count. Both tests can predict the ovarian response to gonadotropin treatment prior to in vitro fertilization (IVF) and are used to individualize ovarian stimulation to achieve an appropriate number of follicles and to avoid ovarian hyperstimulation. A new assay detects low values of AMH and may predict who will benefit from IVF, and who should be referred directly to oocyte donation...
August 7, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28865549/effect-of-oocyte-vitrification-on-embryo-quality-time-lapse-analysis-and-morphokinetic-evaluation
#6
Ana Cobo, Aila Coello, Jose Remohí, Jose Serrano, Jose Maria de Los Santos, Marcos Meseguer
OBJECTIVE: To analyze whether oocyte vitrification may affect subsequent embryo development from a morphokinetic standpoint by means of time-lapse imaging. DESIGN: Observational cohort study. SETTING: University-affiliated private IVF center. PATIENT(S): Ovum donation cycles conducted with the use of vitrified (n = 631 cycles; n = 3,794 embryos) or fresh oocytes (n = 1,359 cycles; n = 9,935 embryos) over 2 years. INTERVENTIONS(S): None...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28860865/advanced-maternal-age-ethical-and-medical-considerations-for-assisted-reproductive-technology
#7
REVIEW
Brittany J Harrison, Tara N Hilton, Raphaël N Rivière, Zachary M Ferraro, Raywat Deonandan, Mark C Walker
OBJECTIVES: This review explores the ethical and medical challenges faced by women of advanced maternal age who decide to have children. Assisted reproductive technologies (ARTs) make post-menopausal pregnancy physiologically plausible, however, one must consider the associated physical, psychological, and sociological factors involved. METHODS: A quasi-systematic review was conducted in PubMed and Ovid using the key terms post-menopause, pregnancy + MeSH terms [donations, hormone replacement therapy, assisted reproductive technologies, embryo donation, donor artificial insemination, cryopreservation]...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28854722/quality-of-life-anxiety-and-depression-of-german-italian-and-french-couples-undergoing-cross-border-oocyte-donation-in-spain
#8
S Madero, S Gameiro, D García, D Cirera, R Vassena, A Rodríguez
STUDY QUESTION: What is the quality of life (QoL) and mental health of infertile heterosexual couples from different nations (Italy, Germany and France) undergoing cross-border oocyte donation (OD) in Spain? SUMMARY ANSWER: Women have lower QoL and more anxiety than their male partners; overall French couples have lower QoL than their Italian and German counterparts. WHAT IS KNOWN ALREADY: In Europe, thousands of couples move across national borders annually to seek ARTs, primarily OD, driven mainly by legal restrictions in their countries of origin...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28854595/dormancy-and-activation-of-human-oocytes-from-primordial-and-primary-follicles-molecular-clues-to-oocyte-regulation
#9
E H Ernst, M L Grøndahl, S Grund, K Hardy, A Heuck, L Sunde, S Franks, C Y Andersen, P Villesen, K Lykke-Hartmann
STUDY QUESTION: Do specific transcriptome dynamics in human oocytes from primordial and primary follicles identify novel pathways in oocyte activation? SUMMARY ANSWER: The transcriptomic profiles in oocytes from primordial and primary follicles, respectively, revealed several new canonical pathways as putative mediators of oocyte dormancy and activation. WHAT IS KNOWN ALREADY: Cellular signaling pathways including PI3K/AKT and AKT/mTOR as well as TGF-β and IGF signaling are known to regulate the primordial-to-primary transition in mammalian follicle development...
August 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28837025/comparison-of-two-different-dosage-of-gnrh-agonist-as-ovulation-trigger-in-oocyte-donors-a-randomized-controled-trial
#10
Sonia Morales Zarcos, Pamela Valdivieso Mejía, Carla Donado Stefani, Pascual Sánchez Martin, Fernando Sánchez Martin
OBJECTIVE: To compare the results obtained with two different GnRH agonist dosages: 0.3mg versus 0.4mg to trigger ovulation in oocyte donor cycles. METHODS: Experimental controlled randomized trial including 40 patients from a private practice center. The patients were randomized into two groups. Group A received a single dose of Triptorelin 0.3mg (Decapeptyl®) 36hours before pick-up. Group B patients received Triptorelin 0.4mg (Decapeptyl®) before pick-up to final oocyte maturation...
September 1, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28822010/vitrification-of-human-immature-oocytes-before-and-after-in-vitro-maturation-a-review
#11
REVIEW
Mohammad Ali Khalili, Abbas Shahedi, Sareh Ashourzadeh, Stefania Annarita Nottola, Guido Macchiarelli, Maria Grazia Palmerini
The use of immature oocytes subjected to in vitro maturation (IVM) opens interesting perspectives for fertility preservation where ovarian reserves are damaged by pathologies or therapies, as in PCO/PCOS and cancer patients. Human oocyte cryopreservation may offer some advantages compared to embryo freezing, such as fertility preservation in women at risk of losing fertility due to oncological treatment or chronic disease, egg donation and postponing childbirth. It also eliminates religious and/or other ethical, legal, and moral concerns of embryo freezing...
August 18, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28815355/egg-donation-of-vitrified-oocytes-bank-produces-similar-pregnancy-rates-by-blastocyst-transfer-when-compared-to-fresh-cycle
#12
Thais S Domingues, Ana Paula Aquino, Bruna Barros, Raquel Mazetto, Mariana Nicolielo, Carolina M Kimati, Talita Devecchi, Tatiana C S Bonetti, Paulo C Serafini, Eduardo L A Motta
PURPOSE: Advances in reproductive techniques, mainly the introduction of oocyte vitrification, have provided the opportunity to conceive from oocyte banks. The aim of this study was to compare the clinical outcomes of fresh and vitrified oocytes in an egg donation program following blastocyst transfer. METHODS: This retrospective observational study included 504 oocyte donation cycles. All donor women were younger than 30 years of age. The recipient cycles were divided into two groups: fresh oocytes (n = 78) or vitrified oocytes (n = 426)...
August 16, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28804713/comment-on-are-patients-with-polycystic-ovarian-syndrome-ideal-candidates-for-oocyte-donation
#13
COMMENT
Sahni Chetan, Rima Dada
No abstract text is available yet for this article.
2017: BioMed Research International
https://www.readbyqxmd.com/read/28687208/assisted-reproduction-techniques-in-latin-america-the-latin-american-registry-2014
#14
Fernando Zegers-Hochschild, Juan Enrique Schwarze, Javier Crosby, Carolina Musri, Maria Teresa Urbina
Multinational data on assisted reproduction techniques (IVF and intractytoplasmic sperm injection [ICSI], frozen embryo transfer, oocyte donation, preimplantation genetic diagnosis and fertility preservation) were collected from 159 institutions in 15 Latin American countries. A total of 41.34% of IVF-ICSI cycles were conducted in women aged 35-39 years and 23.35% in women aged 40 years and older. After removing freeze-all cases, delivery rate per oocyte retrieval was 25.05% for ICSI and 27.41% for IVF. Multiple births included 20...
September 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28687207/high-risk-of-preterm-birth-and-low-birth-weight-after-oocyte-donation-ivf-analysis-of-133-785-live-births
#15
Mohan Shashikant Kamath, Belavendra Antonisamy, Mariano Mascarenhas, Sesh Kamal Sunkara
A higher risk of pregnancy complications occurs after assisted reproductive techniques compared with spontaneously conceived pregnancies. This is attributed to the underlying infertility and assisted reproduction technique procedures involved during treatment. It is a matter of interest whether use of donor oocytes affects perinatal outcomes compared with pregnancies after autologous IVF. Anonymized data were obtained from the Human Fertilization and Embryology Authority. The analysis included 5929 oocyte donation and 127,856 autologous IVF live births...
September 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28670431/evaluation-on-hope-and-psychological-symptoms-in-infertile-couples-undergoing-assisted-reproduction-treatment
#16
Reza Omani Samani, Samira Vesali, Behnaz Navid, Bahareh Vakiliniya, Maryam Mohammadi
BACKGROUND: This study evaluated hope, depression, anxiety, and stress among three groups of infertile couples. MATERIALS AND METHODS: This cross-sectional study consisted of three groups of infertile couples-candidates for oocyte donation (n=60), embryo donation (n=60), and normal infertile (n=60). Participants included couples seen at Royan Institute, Tehran, Iran between 2013-2014 who were at least 18 years of age and could read and write in Persian. Participants provided demographic and general characteristics and completed the Persian version of the Adult Trait Hope Scale (hope, agency and pathway) and Depression, Anxiety, and Stress Scale (DASS)...
July 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28670425/vitrification-of-human-germinal-vesicle-oocytes-before-or-after-in-vitro-maturation
#17
Evangelia Kasapi, Byron Asimakopoulos, Katerina Chatzimeletiou, Stamatios Petousis, Yannis Panagiotidis, Nikos Prapas, Nikos Nikolettos
BACKGROUND: The use of immature oocytes derived from stimulated cycles could be of great importance, particularly for urgent fertility preservation cases. The current study aimed to determine whether in vitro maturation (IVM) was more successful before or after vitrification of these oocytes. MATERIALS AND METHODS: This prospective study was performed in a private in vitro fertilization (IVF) center. We collected 318 germinal vesicle (GV) oocytes from 104 stimulated oocyte donation cycles...
July 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28668152/endometrial-receptivity-in-eutopic-endometrium-in-patients-with-endometriosis-it-is-not-affected-and%C3%A2-let-me-show-you-why
#18
REVIEW
Jose Miravet-Valenciano, María Ruiz-Alonso, Eva Gómez, Juan A Garcia-Velasco
Many women with endometriosis experience compromised fertility. This disease clearly exerts quantitative damage on the ovaries, and perhaps, also qualitative damage. However, it remains controversial whether endometrial receptivity is compromised. Here we review the evidence from basic transcriptomic signature data to clinical data from an oocyte donation model and find support for the concept that endometrial receptivity is not impaired in women with endometriosis when healthy embryos reach the endometrial cavity...
July 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28638367/gnrh-agonist-trigger-and-lh-activity-luteal-phase-support-versus-hcg-trigger-and-conventional-luteal-phase-support-in-fresh-embryo-transfer-ivf-icsi-cycles-a-systematic-prisma-review-and-meta-analysis
#19
REVIEW
Thor Haahr, Matheus Roque, Sandro C Esteves, Peter Humaidan
INTRODUCTION: The use of GnRH agonist (GnRHa) for final oocyte maturation trigger in oocyte donation and elective frozen embryo transfer cycles is well established due to lower ovarian hyperstimulation syndrome (OHSS) rates as compared to hCG trigger. A recent Cochrane meta-analysis concluded that GnRHa trigger was associated with reduced live birth rates (LBRs) in fresh autologous IVF cycles compared to hCG trigger. However, the evidence is not unequivocal, and recent trials have found encouraging reproductive outcomes among couples undergoing GnRHa trigger and individualized luteal LH activity support...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28622634/type-of-gonadotropin-used-during-controlled-ovarian-stimulation-induces-differential-gene-expression-in-human-cumulus-cells-a-randomized-study
#20
María Cruz, Antonio Requena, David Agudo, Juan Antonio García-Velasco
BACKGROUND: The cumulus-oocyte complex plays a central role in the regulation of folliculogenesis where it is important for the maturation, reprogramming, and fertilization of oocytes. Consequently, cumulus cell gene expression profiling is being explored as a promising method for assessing oocyte competence in the near future. Through DNA microarray technology, we analyzed the potential differences in the gene expression profiles of cumulus cells from preovulatory follicles after controlled ovarian stimulation using different types of gonadotropins...
June 8, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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