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Taewoong Rho, Mila Jung, Min Won Lee, Young-Won Chin, Kee Dong Yoon
Efficient high-performance countercurrent chromatography methods were developed to isolate five typical compounds from the extracts of Gentiana macrophylla. n-Butanol soluble extract of G. macrophylla contained three hydrophilic iridoids, loganic acid (1), swertiamarin (2) and gentiopicroside (3), and a chromene derivative, macrophylloside D (4) which were successfully isolated by flow rate gradient (1.5 mL/min in 0-60 min, 5.0 mL/min in 60-120 min), and consecutive flow rate gradient HPCCC using n-butanol/0...
October 24, 2016: Journal of Separation Science
M I Alvarez-Mora, L Rodriguez-Revenga, I Madrigal, M Guitart-Mampel, G Garrabou, M Milà
Mitochondrial involvement plays an important role in neurodegenerative diseases. At least one-third of adult carriers of a FMR1 premutation (55-200 CGG repeats) are at risk of presenting an adult-onset neurodegenerative disorder known as fragile X-associated tremor/ataxia syndrome (FXTAS). In an attempt to provide new insights into the mechanisms involved in the pathogenesis of FXTAS, we characterized mitochondrial function and dynamics by the assessment of oxidative respiratory chain function, mitochondrial content, oxidative stress levels, and mitochondrial network complexity...
October 22, 2016: Molecular Neurobiology
Luke David Knibbs, Craig P Coorey, Matthew John Bechle, Christine Therese Cowie, Mila Dirgawati, Jane S Heyworth, Guy Barrington Marks, Julian D Marshall, Lidia Morawska, Gavin Pereira, Michael G Hewson
Including satellite observations of nitrogen dioxide (NO2) in land-use regression (LUR) models can improve their predictive ability, but requires rigorous evaluation. We used 123 passive NO2 samplers sited to capture within-city and near-road variability in two Australian cities (Sydney and Perth) to assess the validity of annual mean NO2¬ estimates from existing national satellite-based LUR models (developed with 68 regulatory monitors). The samplers spanned roadside, urban near traffic (≤100 m to a major road), and urban background (>100 m to a major road) locations...
October 21, 2016: Environmental Science & Technology
P S Whitfield, N Herron, W E Guise, K Page, Y Q Cheng, I Milas, M K Crawford
We have examined the crystal structures and structural phase transitions of the deuterated, partially deuterated and hydrogenous organic-inorganic hybrid perovskite methyl ammonium lead iodide (MAPbI3) using time-of-flight neutron and synchrotron X-ray powder diffraction. Near 330 K the high temperature cubic phases transformed to a body-centered tetragonal phase. The variation of the order parameter Q for this transition scaled with temperature T as Q ∼ (Tc-T)(β), where Tc is the critical temperature and the exponent β was close to ¼, as predicted for a tricritical phase transition...
October 21, 2016: Scientific Reports
Vladimir Tomović, Marija Jokanović, Mila Tomović, Milana Lazović, Branislav Šojić, Snežana Škaljac, Maja Ivić, Sunčica Koćić-Tanackov, Igor Tomašević, Aleksandra Martinović
Concentrations of cadmium (Cd) and lead (Pb) were determined in livers (n = 52) and kidneys (n = 52) of female cattle (345-2717 days old) from dairy farms in the region Vojvodina. Cd and Pb were analysed by inductively coupled plasma-optical emission spectrometry, after microwave digestion. Cd and Pb concentrations did not exceed the Serbian and European maximum set limits in any sample. The Cd concentrations in the livers and kidneys ranged from 0.033 to 0.151 mg kg(-1) wet weight and from 0.055 to 0...
October 18, 2016: Food Additives & Contaminants. Part B, Surveillance
Zuzana Sestakova, Katarina Kalavska, Lenka Hurbanova, Dana Jurkovicova, Jan Gursky, Michal Chovanec, Daniela Svetlovska, Vera Miskovska, Jana Obertova, Patrik Palacka, Katarina Rejlekova, Zuzana Sycova-Mila, Silvia Cingelova, Stanislav Spanik, Jozef Mardiak, Miroslav Chovanec, Michal Mego
Germ cell tumors (GCTs) are extraordinarily sensitive to cisplatin (CDDP)-based chemotherapy. DNA damage represents one of the most important factors contributing to toxic effects of CDDP-based chemotherapy. This study was aimed to evaluate the prognostic value of DNA damage level in peripheral blood lymphocytes (PBLs) from chemo-naïve GCT patients. PBLs isolated from 59 chemotherapy-naïve GCT patients were included into this prospective study. DNA damage levels in PBLs were evaluated by the Comet assay and scored as percentage tail DNA by the Metafer-MetaCyte analyzing software...
October 7, 2016: Oncotarget
Daniel Turudic, Danica Batinic, Anja Tea Golubic, Mila Lovric, Danko Milosevic
: Diagnostic criteria for determination of inclination towards idiopathic calcium oxalate (CaOx) urolithiasis based on biochemical urine parameters are not sufficiently well defined in children. The aim of this study was to determine the risk of CaOx urolithiasis in children from concentrations of calcium, oxalate, citrate, and glycosaminoglycans in urine and their ratios, all standardized in respect to creatinine. We collected and analyzed 24-h urine samples of children with CaOx urolithiasis (n = 61) and compared with urine samples of matched control group of healthy children (n = 25)...
October 11, 2016: European Journal of Pediatrics
O Vallès-Fructuoso, B Ruiz-de Pablo, M Fernández-Plaza, V Fuentes-Milà, O Vallès-Fructuoso, G Martínez-Estalella
OBJECTIVE: To determine the perspective of intensive care nursing staff on the limitation of life support treatment (LLST) in the Intensive Care Units. METHOD: An exploratory qualitative study was carried out by applying the theory of Strauss and Corbin as the analysis tool. Constructivist paradigm. POPULATION: Nursing staff from three Intensive Care Units of Hospital Universitari de Bellvitge. Convenience sampling to reach theoretical saturation of data...
October 1, 2016: Enfermería Intensiva
Katarina Kalavska, Michal Chovanec, Miriam Zatovicova, Martina Takacova, Paulina Gronesova, Daniela Svetlovska, Magdalena Baratova, Vera Miskovska, Jana Obertova, Patrik Palacka, Jan Rajec, Zuzana Sycova-Mila, Zuzana Cierna, Karol Kajo, Stanislav Spanik, Pavel Babal, Jozef Mardiak, Silvia Pastorekova, Michal Mego
Despite the fact that testicular germ cell tumors (TGCTs) are one of the most chemosensitive solid tumors, a small proportion of patients fail to be cured following cisplatin-based first line chemotherapy. Upregulation of carbonic anhydrase IX (CA IX) in various solid tumors is associated with poor outcome. The current prospective study investigated the prognostic value of serum CA IX level in TGCTs. In total, 83 patients (16 non-metastatic following orchiectomy with no evidence of disease, 57 metastatic chemotherapy-naïve and 10 metastatic relapsed chemotherapy-pretreated) starting adjuvant and/or new line of chemotherapy and 35 healthy controls were enrolled in the study...
October 2016: Oncology Letters
Jessica K Witt, J Eric T Taylor, Mila Sugovic, John T Wixted
No abstract text is available yet for this article.
September 1, 2016: Journal of Vision
Tanja T Radović, Svetlana D Grujić, Srđan R Kovačević, Mila D Laušević, Milan A Dimkić
In the present work, the sorption ability of 17 pharmaceutical compounds, two metabolites, and 15 pesticides (34 target compounds in total) onto four different river sediments was investigated separately. Selected compounds present the most frequently prescribed pharmaceuticals in human and animal medicine and the most frequently used pesticides in agriculture. Their presence into the surface, ground, and waste waters was confirmed into the numerous papers in literature, as well as their presence into the river sediments (for some of them)...
September 29, 2016: Environmental Science and Pollution Research International
S Sivakumar, F S Taccone, K A Desai, C Lazaridis, M Skarzynski, M Sekhon, W Henderson, D Griesdale, L Chapple, A Deane, L Williams, R Strickland, K Lange, D Heyland, M Chapman, M J Rowland, P Garry, J Westbrook, R Corkill, C A Antoniades, K T Pattinson, G Fatania, A J Strong, R B Myers, C Lazaridis, C M Jermaine, C S Robertson, C G Rusin, J Hofmeijer, L Sondag, M C Tjepkema-Cloostermans, A Beishuizen, F H Bosch, M J A M van Putten, L Carteron, C Patet, D Solari, M Oddo, M A Ali, C Dias, R Almeida, A Vaz-Ferreira, J Silva, E Monteiro, A Cerejo, A P Rocha, A A Elsayed, A M Abougabal, B N Beshey, K M Alzahaby, S Pozzebon, A Blandino Ortiz, S Cristallini, O Lheureux, A Brasseur, J L Vincent, J Creteur, F S Taccone, M Hravnak, K Yousef, Y Chang, E Crago, R M Friedlander, S A Abdelmonem, S A Tahon, T A Helmy, H S Meligy, F Puig, I Dunn-Siegrist, J Pugin, S Gupta, D Govil, S Srinivasan, S J Patel, J K N, A Gupta, D S Tomar, M Shafi, R Harne, D P Arora, N Talwar, S Mazumdar, E E Papakrivou, D Makris, E Manoulakas, B Tsolaki, B Karadodas, E Zakynthinos, I Palacios Garcia, A Diaz Martin, V Sanchez Encinares, M Pachón Ibañez, J Garnacho Montero, G Labrador, T Cebrero Cangueiro, V Poulose, J Koh, J W Kam, H Yeter, A Kara, O Aktepe, A Topeli, I Tsolakoglou, G Intas, P Stergiannis, A A Kolaros, E Chalari, E Athanasiadou, A Martika, G Fildisis, V Faivre, C Mengelle, B Favier, D Payen, A Poppe, M S Winkler, E Mudersbach, J Schreiber, M L Wruck, E Schwedhelm, S Kluge, C Zöllner, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, A García-de la Torre, M V de la Torre-Prados, T Tsvetanova-Spasova, P Nuevo-Ortega, C Rueda-Molina, A Fernández-Porcel, E Camara-Sola, L Salido-Díaz, A García-Alcántara, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, D E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, B Suberviola, J Riera, L Rellan, M Sanchez, J C Robles, E Lopez, R Vicente, E Miñambres, M Santibañez, M Le Guen, J Moore, N Mason, M Windpassinger, O Plattner, E Mascha, D I Sessler, Outcomes Research, U Melia, J Fontanet, J P van den Berg, M M R F Struys, H E M Vereecke, E W Jensen, P J T Rood, F van de Schoor, K van Tertholen, P Pickkers, M van den Boogaard, Z J Beardow, H Redhead, K Paramasivam, T Numan, M van den Boogaard, A M Kamper, P Rood, L M Peelen, P M Zeman, A J Slooter, C E van Ewijk, G E Jacobs, A R J Girbes, S N Myatra, M M Harish, N R Prabu, S Siddiqui, A P Kulkarni, J V Divatia, L D Murbach, M A Leite, E F Osaku, C R L M Costa, M Pelenz, N M Neitzke, M M Moraes, J L Jaskowiak, M M M Silva, R S Zaponi, L R L Abentroth, S M Ogasawara, A C Jorge, P A D Duarte, N Hernández-Sánchez, L A Sánchez-Hurtado, F J García-Guillen, S A Ñamendys-Silva, B Maghsoudi, M Emami, M B Khosravi, F Zand, H R Tabatabaie, M Masjedi, G Sabetiyan, A Mokri, J Troubleyn, M Diltoer, R Jacobs, D N Nguyen, E De Waele, J De Regt, P M Honoré, V Van Gorp, H D Spapen, R S Contreras, N D Toapanta, G Moreno, J Sabater, H Torrado, M Gonzalez, M Marin, E Farigola, A Gonzalez, J Fernandez, A Vera, X Gisbert, C Juliá, J Uya, L Corral, I Elias-Jones, L Gemmell, A MacKay, D Randall, A Adwaney, M Blunden, J R Prowle, C J Kirwan, N Thomas, A Martin, H Owen, L Darwin, D Conway, D Atkinson, M Sharman, J Moore, C Barbanti, J Amour, P Gaudard, B Rozec, P Mauriat, M M'rini, P L Leger, G Cambonie, J M Liet, C Girard, S Laroche, P Damas, Z Assaf, G Loron, L Lecourt, P Pouard, D Randall, A Adwaney, M Blunden, J R Prowle, C J Kirwan, S H Kim, S Na, J Kim, S Y Oh, C W Jung, S H Yoo, S H Min, E J Chung, H Lee, N J Lee, K W Lee, K S Suh, H G Ryu, D C Marshall, R J Goodson, J D Salciccioli, J Shalhoub, E K Potter, J Kirk-Bayley, N D Karanjia, L G Forni, B C Creagh-Brown, M Bossy, M Nyman, A Tailor, B Creagh-Brown, D D'Antini, S Spadaro, F Valentino, F Sollitto, G Cinnella, L Mirabella, F J Redondo Calvo, N Bejarano, D Padilla, V Baladron, P Villajero, R Villazala, J Redondo, A S Yuste, J Liu, F Shen, J L Teboul, N Anguel, A Beurton, N Bezaz, C Richard, X Monnet, T Fossali, R Colombo, D Ottolina, M Rossetti, C Mazzucco, A Marchi, A Porta, E Catena, K H Tollisen, G Ø Andersen, F Heyerdahl, D Jacobsen, M C de Waard, A R J Girbes, M C O van IJzendoorn, H Buter, W P Kingma, G J Navis, E C Boerma, J Rulisek, M Balik, S Zacharov, H S Kim, S J Jeon, H Namgung, E Lee, E Lee, Y J Cho, Y J Lee, A Huang, L Cioccari, N Luethi, J Mårtensson, R Bellomo, M Forsberg, G Edman, J Höjer, S Forsberg, M T Chiquito Freile, F N Hidalgo, J A Martinez Molina, R Lecumberri, A Figuerola Rosselló, P Medrano Travieso, G Tuero Leon, J Gonzalez Sanchez, L Sahuquillo Frias, D Balsells Rosello, J A Garcia Verdejo, J A Noria Serrano, D Winterwerp, T van Galen, A Vazin, I Karimzade, A Zand, E Ozen, S Ekemen, A Akcan, E Sen, B Buyukkidan Yelken, N Kureshi, L Fenerty, G Thibault-Halman, M Erdogan, S Walling, R S Green, D B Clarke, P Briassoulis, K Kalimeris, A Ntzouvani, T Nomikos, K Papaparaskeva, E Politi, G Kostopanagiotou, K Crewdson, M Rehn, A Weaver, K Brohi, D Lockey, S Wright, K Thomas, C Baker, L Mansfield, V Stafford, C Wade, G Watson, A Bryant, T Chadwick, J Shen, J Wilkinson, J Furneval, A Henderson, K Hugill, P Howard, A Roy, S Bonner, S Baudouin, C Sánchez Ramírez, S Hípola Escalada, M A Hernández Viera, M Cabrera Santana, L Caipe Balcázar, N Sangil Monroy, F Artiles Campelo, C F Lübbe Vázquez, P Saavedra Santana, S Ruiz Santana, L Carteron, C Patet, H Quintard, D Solari, P Bouzat, M Oddo, T Wollersheim, J Malleike, K Haas, N Carbon, J Schneider, C Birchmeier, J Fielitz, S Spuler, S Weber-Carstens, L Enseñat, A Pérez-Madrigal, P Saludes, L Proença, G Gruartmoner, C Espinal, J Mesquida, W Huber, M Eckmann, F Elkmann, A Gruber, T Lahmer, U Mayr, A Herner, R Schellnegger, J Schneider, R M Schmid, W Ayoub, W Samy, A Esmat, A Battah, S Mukhtar, W Mongkolpun, D Orbegozo Cortés, C P R Cordeiro, J L Vincent, J Creteur, S Funcke, H Groesdonk, B Saugel, G Wagenpfeil, S Wagenpfeil, D A Reuter, M M Fernandez, R Fernandez, M Magret, A González-Castro, M T Bouza, M Ibañez, C García, B Balerdi, A Mas, V Arauzo, J M Añón, F Ruiz, J Ferreres, R Tomás, M Alabert, A I Tizón, S Altaba, N Llamas, E C Goligher, E Fan, M Herridge, S Vorona, M Sklar, M Dres, N Rittayamai, A Lanys, C Urrea, G Tomlinson, W D Reid, G D Rubenfeld, B P Kavanagh, L J Brochard, N D Ferguson, A Serpa Neto, M Gama de Abreu, P Pelosi, M J Schultz, C Guérin, L Papazian, J Reignier, L Ayzac, A Loundou, J M Forel, C Rolland-Debord, C Bureau, T Poitou, M Clavel, S Perbet, N Terzi, A Kouatchet, T Similowski, A Demoule, N Hunfeld, Z Trogrlic, S Ladage, R J Osse, B Koch, W Rietdijk, J Devlin, M van der Jagt, E Picetti, P Ceccarelli, F Mensi, L Malchiodi, S Risolo, I Rossi, M V Antonini, F Servadei, M L Caspani, A Roquilly, S Lasocki, P Seguin, T Geeraerts, P F Perrigault, C Dahyot-Fizelier, C Paugam-Burtz, F Cook, R Cinotti, D Demeure Dit Latte, P J Mahe, C Fortuit, F Feuillet, K Asehnoune, C Marzorati, S Spina, V Scaravilli, A Vargiolu, M Riva, C Giussani, E Sganzerla, G Citerio, S Barbadillo, F J González de Molina, F Álvarez-Lerma, A Rodríguez, T Zakharkina, I Martin-Loeches, S Matamoros, P Povoa, A Torres, J Kastelijn, J J Hofstra, M de Jong, M Schultz, P Sterk, A Artigas, L J Bos, A S Moreau, I Martin-Loeches, P Povoa, J Salluh, A Rodriguez, S Nseir, E de Jong, J A van Oers, A Beishuizen, A R J Girbes, M W N Nijsten, D W de Lange, D Bonvicini, D Labate, L Benacchio, A Olivieri, E Pizzirani, J C Lopez-Delgado, M Gonzalez-Romero, V Fuentes-Mila, D Berbel-Franco, I Romera-Peregrina, A Martinez-Pascual, J Perez-Sanchez, R Abellan-Lencina, R E Ávila-Espinoza, G Moreno-Gonzalez, F Sbraga, S Griffiths, M P W Grocott, B Creagh-Brown, J Doyle, P Wilkerson, Y Soon, S Huddart, M Dickinson, A Riga, A Zuleika, K Miyamoto, Y Kawazoe, T Morimoto, T Yamamoto, A Fuke, A Hashimoto, H Koami, S Beppu, Y Katayama, M Ito, Y Ohta, H Yamamura, S L Rygård, L B Holst, J Wetterslev, P I Johansson, A Perner, I W Soliman, D W de Lange, D van Dijk, J J M van Delden, O L Cremer, A J C Slooter, L M Peelen, D McWilliams, C Snelson, A Das Neves, C I Loudet, M Busico, D Vazquez, D Villalba, M Veronesi, A Lischinsky, F J L López, L Benito Mori, G Plotnikow, A Díaz, S Giannasi, R Hernandez, L Krzisnik, C Cecotti, L Viola, R Lopez, J P Sottile, G Benavent, E Estenssoro, C M Chen, C C Lai, K C Cheng, W Chou, K S Chan, L E Roeker, C M Horkan, F K Gibbons, K B Christopher, P J M Weijs, K M Mogensen, J D Rawn, M K Robinson, K B Christopher, Z Tang, C Qiu, B Ouyang, C Cai, X Guan, T Regueira, L Cea, S Juan Carlos, B Elisa, C Puebla, A Vargas, M K Poulsen, L P Thomsen, S Kjærgaard, S E Rees, D S Karbing, T Wollersheim, S Frank, M C Müller, N M Carbon, V Skrypnikov, P A Pickerodt, R Falk, A Mahlau, S Weber-Carstens, A Lee, R Inglis, R Morgan, G Barker, K Kamata, T Abe, D Saitoh, Y Tokuda, R S Green, M B Butler, M Erdogan, H Tae Hwa, L Jae Gil, R Hernández Vaquero, E Rodriguez-Ruiz, A Lopez Lago, J L Garcia Allut, A Estany Gestal, M A Garcia Gonzalez, D O Thomas-Rüddel, D Schwarzkopf, C Fleischmann, K Reinhart, S Suwanpasu, Y Sattayasomboon, N M Filgueiras Filho, J C A Oliveira, C S Ballalai, C V De Lucia, G P Araponga, L N Veiga, C S Silva, M E Garrido, B B Ramos, E F Ricaldi, S S Gomes, L Gemmell, A MacKay, C Wright, R I Docking, P Doherty, E Black, P Stenhouse, M P Plummer, M E Finnis, L K Phillips, P Kar, S Bihari, V Biradar, S Moodie, M Horowitz, J E Shaw, A M Deane, T Yatabe, S Inoue, M Sakaguchi, M Egi, Y Ali Abdelhamid, M P Plummer, M E Finnis, L K Phillips, P Kar, S Bihari, V Biradar, S Moodie, M Horowitz, J E Shaw, A M Deane, M Hokka, M Egi, S Mizobuchi, P Kar, M Plummer, Y Ali Abdelhamid, E Giersch, M Summers, S Hatzinikolas, S Heller, M Chapman, K Jones, M Horowitz, A Deane, R Schweizer, M Jacquet-Lagreze, P Portran, S Junot, B Allaouchiche, J L Fellahi, P Guerci, B Ergin, A Kapucu, C Ince, L Cioccari, N Luethi, M Crisman, R Bellomo, J Mårtensson, C Righy Shinotsuka, D Fagnoul, A Brasseur, D Orbegozo, J L Vincent, J C Preiser, J C Preiser, O Lheureux, A Thooft, S Brimioulle, J L Vincent, H Iwasaka, S Tahara, M Nagamine, A Ichigatani, A Rugerio Cabrera, E Monares Zepeda, J Franco Granillo, J S Aguirre Sánchez, A A Tanaka Montoya, A Pedraza Montenegro, G A Gálvez Blanco, C M Coronado Robles, A Drolz, T Horvatits, K Roedl, K Rutter, S Kluge, G C Funk, B Schneeweiss, V Fuhrmann, G Sabetian, F Pooresmaeel, F Zand, S Ghaffaripour, A Farbod, H Tabei, L Taheri, R Anandanadesan, V Metaxa, C Teixeira, S M Pereira, P Hernández-Marrero, A S Carvalho, M Beckmann, C S Hartog, D Schwarzkopf, A Raadts, A Robertsen, R Førde, N O Skaga, E Helseth, S Honeybul, K Ho, P Martinez Lopez, M Nieto Gonzalez, P Nuevo Ortega, E Camara Sola, T Spasova, M V de la Torre-Prados, O Kopecky, K Rusinova, P Waldauf, Z Cepeplikova, M Balik, J Palamidessi Domínguez, P Matia Almudevar, S Alcántara Carmona, J J Rubio Muñoz, D Palacios Castañeda, A Naharro Abellán, P Rodríguez Villamizar, J Veganzones Ramos, L Pérez Pérez, A Pérez Lucendo, M Camós Ejarque, A Estella, V Lopez Camps, M C Martín, N Masnou, S Barbosa, A Varela, I Palma, L Cristina, E Nunes, I Pereira, G Campello, C Granja, R Pande, M Pandey, S Varghese, M Chanu, M J Van Dam, E W M T Ter Braak, A Estella, M Gracia, R Viciana, M Recuerda, L Perez Fontaiña, B Tharmalingam, F Kovari, L Rose, M Mcginlay, R Amin, K Burns, B Connolly, N Hart, P Jouvet, S Katz, D Leasa, C Mawdsley, D Mcauley, M Schultz, B Blackwood, S Denham, R Worrall, M Arshad, P Isherwood, A Khadjibaev, D Sabirov, A Rosstalnaya, F Parpibaev, V Sharipova, G A Galvez Blanco, C I Olvera Guzman, J S Aguirre Sánchez, J Franco Granillo, S Gupta, D Govil, S Srinivasan, S J Patel, J K N, A Gupta, M Shafi, D S Tomar, R Harne, D P Arora, N Talwar, S Mazumdar, Y S Cha, S J Lee, N Tyagi, R K Rajput, S Taneja, V K Singh, S C Sharma, S Mittal, B K Rao, J Ayachi, N Fraj, S Romdhani, A Khedher, K Meddeb, N Sma, A Azouzi, R Bouneb, I Chouchene, M El Ghardallou, M Boussarsar, R Jennings, E Walter, J M Ribeiro, I Moniz, R Marçal, A C Santos, C Candeias, Z Costa E Silva, S E Zamora Gomez, O R Perez Nieto, J A Castanon Gonzalez, A I Vasquez Cuellar, H Mildh, V Pettilä, A M Korhonen, S Karlsson, T Ala-Kokko, M Reinikainen, S T Vaara, M Zaleska-Kociecka, M Grabowski, M Dąbrowski, S Wozniak, K Piotrowska, M Banaszewski, J Imiela, J Stepinska, A González Pérez, P Florez Ordoñez, A Giribet, M A Alonso Cuervo, R Alonso Cuervo, M A Rodriguez Esteban, L Iglesias Fraile, C Ponte Mittelbrum, G Muñiz Albaiceta, J Koeze, F Keus, W Dieperink, I C C van der Horst, M van Meurs, J G Zijlstra, S Roberts, C Hernandez Caballero, G Isgro, D Hall, S Beitland, A-M S Trøseid, B S Brusletto, B E Waldum-Grevbo, J P Berg, K Sunde, D García Huertas, F Manzano, M M Jiménez- Quintana, A Osuna, F Santiago-Ruiz, C Rodríguez-Mejías, R Wangensteen, H R Jamaati, M Masjedi, F Zand, S M R Hashemian, G Sabetian, G Abbasi, V Khaloo, S H A Tabei, A Kafilzadeh, H Haddad Bakhodaei, J A Diaz, R Silva, D J Garcia, E Luis, M N Gomez, R Soriano, P L Gonzalez, I A Ibrahim, M M Rafik, A M Al-Ansary, M A Algendi, A A Ali, V Fuhrmann, K Roedl, T Horvatits, A Drolz, K Rutter, D Benten, J Kluwe, S Siedler, S Kluge, I Adedugbe, G T Bird, R M Kennedy, S Sharma, M B Butler, G Yugi, B A Haroon, T Witter, W Khaliq, M Singer, A A Havaldar, B Krishna, S Sriram, E D Valenzuela Espinoza, M O Pozo, V S Kanoore Edul, M Furche, M F Motta, A Risso Vazquez, P N Rubatto Birri, C Ince, A Dubin, A Dogliotti, A Ramos, C Lovesio, E Delile, R Nevière, P-A Thiébaut, J Maupoint, P Mulder, D Coquerel, S Renet, J C do Rego, J Rieusset, V Richard, F Tamion, W Khaliq, D T Andreis, M Singer, B Smit, Y M Smulders, M C de Waard, H M Oudemans van Straaten, A R J Girbes, E C Eringa, A M E Spoelstra-de Man, L Alegría, D Soto, C Luengo, J Gomez, N Jarufe, A Bruhn, R Castro, E Kattan, P Tapia, R Rebolledo, P Achurra, G Ospina-Tascón, J Bakker, G Hernández, P Bertini, F 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G Drossos, Z Uz, Y Ince, R Papatella, E Bulent, P Guerci, C Ince, B De Mol, V Vicka, D Gineityte, D Ringaitiene, I Norkiene, J Sipylaite, C Möller, C Fleischmann, D O Thomas-Rueddel, V Vlasakov, B Rochwerg, P Theurer, L Gattinoni, K Reinhart, C S Hartog, A González Pérez, J Zanabili Al Sibai, P Martinez Camblor, P Alvarez Fernandez, J M García Gala, J Silba Guisasola, G Muñiz Albaiceta, T Tamura, T Yatabe, I Miyajima, K Yamashita, M Yokoyama, F Ampatzidou, G Kehagioglou, E Dalampini, M Nastou, A Baddour, A Ignatiadis, T Asteri, G Drossos, K E Hathorn, S W Purtle, C M Horkan, F K Gibbons, K B Christopher, M V Viana, T A Tonietto, L A Gross, V L Costa, A L J Tavares, B O Lisboa, R B Moraes, S R Vieira, L V Viana, M J Azevedo, G D Ceniccola, R S F Pequeno, T P Holanda, V S Mendonça, W M C Araújo, L S F Carvalho, E Segaran, L Vickers, K Brinchmann, I Wignall, F Rubulotta, I De Brito-Ashurst, R Del Olmo, M J Esteban, C Vaquerizo, R Carreño, V Gálvez, G Kaminsky, B Nieto, M Fuentes, M A De la Torre, E Torres, A Alonso, C Velayos, T Saldaña, A Escribá, J Grip, R Kölegård, P Sundblad, O Rooyackers, Ben Naser, F Jaziri, A Ben Jazia, M Barghouth, O Hentati, W Skouri, M El Euch, M Mahfoudhi, S Turki, K Ben Abdelghni, Ben Abdallah, B N M Maha, J Cánovas, F Sotos, A López, M Lorente, A Burruezo, D Torres, K Polok, A Włudarczyk, J Górka, A Hałek, J Musiał, W Szczeklik, A Ben Jazia, F Jaziri, M Bargouth, M Bennasr, S Turki, K Ben Abdelghani, T Ben Abdallah, H J de Grooth, I L Geenen, J J Parienti, H M Oudemans-van Straaten, H P Shum, H S King, K C Chan, W W Yan, J Gonzalez Londoño, C Lorencio Cardenas, M Morales Pedrosa, C Murcia Gubianas, C Fuster Bertolin, N Vila Batllori, J M Sirvent, K Wykes, J Jack, P Morgan, A Mukhopadhyay, H Y Chan, Y Kowitlawakul, D Remani, C S F Leong, C J Henry, Z A Puthucheary, N Mendsaikhan, T Begzjav, G Lundeg, M Dünser, E D Valenzuela Espinoza, S P Welsh, M F Motta, E Guerra, M C L Zerpa, F Zechner, M Furche, F Berdaguer, P N Rubatto Birri, A Risso-Vazquez, A Dubin, F D Masevicius, D Greaney, A Magee, G Fitzpatrick, R G Lugo-Cob, L A Sánchez-Hurtado, P C Arvizu-Tachiquín, B C Tejeda-Huezo, A A Cano-Oviedo, J A Baltazar-Torres, M S Aydogan, T Togal, A Taha, H Z Chai, C Kam, S S Yang Razali, V Sivasamy, L Y Kuan, V Poulose, M A Lopez Morales, S Castro, T Pires, L Melão, A Krystopchuk, I Pereira, C Granja, L U Taniguchi, E M C Pires, J M Vieira, L C P Azevedo
No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
Gad Rennert, Mila Pinchev, Naomi Gronich, Walid Saliba, Anath Flugelman, Idit Lavi, Hadassah Goldberg, Georgeta Fried, Mariana Steiner, Arie Bitterman, Keren Landsman, Hedy Rennert
PURPOSE: Bisphosphonates are used for treatment or prevention of osteoporosis and of bone metastases. The use of oral bisphosphonates was suggested to be associated with reduced risk of developing breast cancer and their positive influence on breast cancer survival was only demonstrated with third generation bisphosphonates. We studied the association of use of oral bisphosphonates after breast cancer diagnosis on overall and breast cancer survival. EXPERIMENTAL DESIGN: A nested case-control analysis was performed using data from the population-based Breast Cancer in Northern Israel Study (BCINIS)...
September 28, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Antonella Piazza, Paola Rucci, Massimo Clo, Dino Gibertoni, Lucia Camellini, Marinella Di Stani, Maria Pia Fantini, Mila Ferri, Angelo Fioritti
PURPOSE: To estimate the treated prevalence of eating disorders (ED) in Emilia-Romagna, Italy, and to compare health services utilization among age groups and geographical areas. METHODS: The study cohort consists of patients aged 12-64 years with a primary or secondary ED diagnosis, treated in regional healthcare facilities in 2012. Patients were followed up for 1 year from the first contact. Data were extracted from regional administrative databases. RESULTS: The study cohort included 1550 cases, 36...
September 29, 2016: Eating and Weight Disorders: EWD
Amelia Gamini, Anna Coslovi, Mila Toppazzini, Isabella Rustighi, Cristiana Campa, Amedeo Vetere, Sergio Paoletti
CE applications to charged polysaccharides are briefly reported. A simple procedure is presented to determine the esterification degree of a hyaluronan derivative. In this case the degree of substitution was as low as 14 %.The molecular weight distribution of mannuronic oligosaccharides mixture produced by hydrolysis of native polymannuronic is readily calculated from peak area of the species resolved by CE on the basis of a specific degree of polymerization.The influence of the applied electric field strength on the free solution mobility of hyaluronan samples is briefly addressed for molar masses of the order of 10(5) and 10(6) g/mol...
2016: Methods in Molecular Biology
Mila Toppazzini, Anna Coslovi, Marco Rossi, Anna Flamigni, Edi Baiutti, Cristiana Campa
This chapter reports an overview of the recent advances in the analysis of mono- and oligosaccharides by capillary electrophoresis (CE); furthermore, relevant reviews and research articles recently published in the field are tabulated. Additionally, pretreatments and procedures applied to uncharged and acidic carbohydrates (i.e., monosaccharides and lower oligosaccharides carrying carboxylate, sulfate, or phosphate groups) are described.Representative examples of such procedures are reported in detail, upon describing robust methodologies for the study of (1) neutral oligosaccharides derivatized by reductive amination and by formation of glycosylamines; (2) sialic acid derivatized with 2-aminoacridone, released from human serum immunoglobulin G; (3) anomeric couples of neutral glycosides separated using borate-based buffers; (4) unsaturated, underivatized oligosaccharides from lyase-treated alginate...
2016: Methods in Molecular Biology
Mila Petrova, Julia Riley, Julian Abel, Stephen Barclay
BACKGROUND: Electronic Palliative Care Coordination Systems (EPaCCS) are England's pre-eminent initiative in enabling advance care planning and improved communication and coordination at the end of life. EPaCCS have been under development for 8 years after being proposed, as Locality Registers, in the 2008 End of Life Care Strategy for England. EPaCCS are electronic registers or tools and processes for sharing data which aim to enable access to information about dying patients. Striking outcomes have been reported around EPaCCS, such as 77...
September 16, 2016: BMJ Supportive & Palliative Care
Karolina Pakos-Zebrucka, Izabela Koryga, Katarzyna Mnich, Mila Ljujic, Afshin Samali, Adrienne M Gorman
In response to diverse stress stimuli, eukaryotic cells activate a common adaptive pathway, termed the integrated stress response (ISR), to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eukaryotic translation initiation factor 2 alpha (eIF2α) by one of four members of the eIF2α kinase family, which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery. The gene expression program activated by the ISR optimizes the cellular response to stress and is dependent on the cellular context, as well as on the nature and intensity of the stress stimuli...
October 2016: EMBO Reports
Marina Šagud, Bjanka Vuksan-Ćusa, Božina Nada, Mila Lovrić, Alma Mihaljević-Peleš, Milivoj Kramarić
No abstract text is available yet for this article.
September 13, 2016: Journal of Clinical Psychopharmacology
Jelena Bila, Aleksandra Sretenovic, Jelena Jelicic, Natasa Tosic, Irena Glumac, Marija Dencic Fekete, Darko Antic, Milena Todorovic Balint, Olivera Markovic, Zoran Milojevic, Milica Radojkovic, Goran Trajkovic, Mila Puric, Sonja Pavlovic, Biljana Mihaljevic
BACKGROUND: To personalize the treatment approach for patients with multiple myeloma (MM), molecular markers such as cereblon (CRBN) are currently the focus of investigation. The aim of the present study was to test the prognostic significance of CRBN expression in MM patients ineligible for autologous stem cell transplantation (ASCT). PATIENTS AND METHODS: The data from 92 previously untreated patients were analyzed. The distribution according to the International Staging System score was 26...
August 10, 2016: Clinical Lymphoma, Myeloma & Leukemia
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