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https://www.readbyqxmd.com/read/28637590/evaluation-of-readmissions-due-to-surgical-site-infections-a-potential-target-for-quality-improvement
#1
Romil Shah, Emily Pavey, Mila Ju, Ryan Merkow, Ravi Rajaram, Michael W Wandling, Mark E Cohen, Allison Dahlke, Anthony Yang, Karl Bilimoria
INTRODUCTION: Readmissions have become a focus of pay-for-performance programs. Surgical site infections (SSI) are the reason for most readmissions. Readmissions for SSI could be a unique target for quality improvement. METHODS: Readmission risk for SSI were evaluated for patients undergoing colectomies from 2013 to 2014. Hazard models were developed to examine factors associated with and hospital-level variation in risk-adjusted rates of readmission for SSI. RESULTS: Among 59,088 patients at 525 hospitals, the rate of readmissions for SSI ranged from 1...
June 8, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28622787/monitoring-of-the-newborn-dog-and-prediction-of-neonatal-mortality
#2
Hanna Mila, Aurélien Grellet, Marine Delebarre, Claire Mariani, Alexandre Feugier, Sylvie Chastant-Maillard
Despite the high neonatal mortality rate in puppies, pertinent criteria for health evaluation of the newborns are not defined. This study was thus designed to measure and to characterize factors of variation of six health parameters in dog neonates, and to evaluate their value as predictors of neonatal mortality. A total of 347 purebred puppies under identical conditions of housing and management were examined within the first 8h after birth and then at Day 1. The first health evaluation included Apgar score, weight, blood glucose, lactate and β-hydroxybutyrate concentration, rectal temperature and urine specific gravity (SG)...
August 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28617938/fragile-x-syndrome-an-overview-and-update-of-the-fmr1-gene
#3
REVIEW
Montserrat Mila, Maria Isabel Alvarez-Mora, Irene Madrigal, Laia Rodriguez-Revenga
Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability and the leading form of the monogenic cause of autism. FMR1 premutation is the first single-gene cause of primary ovarian failure (FXPOI) and one of the most common causes of ataxia (FXTAS), multiple additional phenotypes such as fibromyalgia, hypothyroidism, migraine headaches, sleep disturbances, sleep apnea, restless legs syndrome, central pain syndrome, neuropathy and neuropsychiatric alterations has been described. Clinical involvement in men and women carrying the FMR1 premutation currently constitutes a real health problem in the society that should be taken into account...
June 15, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28609984/a-new-species-of-i-pamphagus-i-orthoptera-pamphagidae-from-algeria-with-a-key-to-all-the-species-of-the-genus
#4
Naima Benkenana, Bruno Massa
The authors describe Pamphagus milevitanus n. sp. occurring in the North and South highlands of Constantine, in Mila, Setif and Oum-el Bouaghi provinces, where it is fairly common. They compare the characters of this species with those of the most related species of the genus and present a complete plate and a key to all the species of the genus Pamphagus known to date.
April 12, 2017: Zootaxa
https://www.readbyqxmd.com/read/28599819/between-the-best-way-to-deliver-patient-care-and-chaos-and-low-clinical-value-general-practitioners-and-practice-managers-views-on-data-sharing
#5
Mila Petrova, Matthew Barclay, Sam S Barclay, Stephen I G Barclay
OBJECTIVE: In the UK, General Practitioners and Practice Managers are key to enabling health information exchange (typically referred to as 'data sharing'). This study aimed to survey GPs and PMs for familiarity, engagement with and perceptions of patient data sharing. METHODS: Cross-sectional survey. All 107 general practices in England's second largest Clinical Commissioning Group, Cambridgeshire & Peterborough CCG. Descriptive statistics; hierarchical logistic regression; thematic analysis...
August 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28591430/qualitative-hplc-dad-esi-tof-ms-analysis-cytotoxic-and-apoptotic-effects-of-croatian-endemic-centaurea-ragusina-l-aqueous-extracts
#6
Mila Radan, Ivana Carev, Vele Tešević, Olivera Politeo, Vedrana Čikeš Čulić
Centaurea ragusina L., an endemic Croatian plant species, revealed a good cytotoxic activity of aqueous extracts on human bladder (T24) and human glioblastoma (A1235) cancer cell lines. The chemical constituents were tentatively identified using high performance liquid chromatography HPLC-DAD-ESI-TOF-MS in negative ionization mode. The main compounds of herba extract were sesquiterpene lactones: solstitialin A-3, 13 diacetate and epoxyrepdiolide; organic acid: quinic acid. The main compounds of flower extract were organic acids: quinic acid, citric acid and malic acid; sesquiterpene lactone: cynaropicrin; phenolic compounds: chlorogenic acid and phenylpropanoid: syringin...
June 7, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28571612/microbiological-quality-of-argentinian-paprika
#7
María G Melo González, Stella M Romero, Mila Arjona, Ada G Larumbe, Graciela Vaamonde
The aim of this study was to evaluate the microbiological quality of paprika produced in Catamarca, Argentina. Microbiological analyses were carried out for the enumeration of total aerobic mesophilic bacteria, coliforms, yeasts and molds, and the detection of Salmonella in samples obtained from different local producers during three consecutive years. The mycobiota was identified paying special attention to the mycotoxigenic molds. Standard plate counts of aerobic mesophilic bacteria ranged from 2.7×10(5) to 3...
May 29, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28570206/increased-incidence-of-gonorrhoea-and-chlamydia-in-greenland-1990-2012
#8
Mila Broby Johansen, Anders Koch, Jan Wohlfahrt, Mads Kamper-Jørgensen, Steen Hoffmann, Bolette Soborg
BACKGROUND: Since the 1970s, Greenland has presented the highest reported incidence rates of the sexually transmitted infections (STIs) gonorrhoea and chlamydia in the Arctic regions. OBJECTIVE: This study aims to describe sex- and age-specific incidence rates of gonorrhoea and chlamydia from 1990 to 2012 in Greenland, and to evaluate if changes in case definitions, diagnostic procedures and implementation of STI interventions during the period coincide with rate changes...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28569991/the-role-of-5-lipoxygenase-in-aggregatibacter-actinomycetemcomitans-induced-alveolar-bone-loss
#9
Mila Fernandes Moreira Madeira, Celso Martins Queiroz Junior, Jôice Dias Corrêa, Sílvia Maria Cordeiro Werneck, Fabiana Simão Machado, Thiago Mattar Cunha, Gustavo Pompermaier Garlet, Mauro Martins Teixeira, Tarcília Aparecida da Silva, Daniele G Souza
AIM: Leukotrienes (LTs) are pro-inflammatory lipid mediators formed by the enzyme 5-lipoxygenase (5-LO). The involvement of 5-LO metabolites in periodontal disease (PD) is not well defined. This study aimed to assess the role of 5-LO in experimental PD induced by Aggregatibacter actinomycetemcomitans (Aa). MATERIAL AND METHODS: In vivo experiments were carried out using SV129 wild type (WT) and 5-LO deficient (5lo(-/-) ) mice inoculated with Aa. Osteoclasts were stimulated in vitro with AaLPS in the presence or not of selective inhibitors of the 5-LO pathway, or LTB4 or platelet-activating factor (PAF), since PAF has already been shown to increase osteoclast activity...
June 1, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28567315/respiratory-syncytial-virus-associated-myocarditis-requiring-venoarterial-extracorporeal-membrane-oxygenation
#10
Anamaria Milas, Aditya Shah, Neesha Anand, Meghan Saunders-Kurban, Samir Patel
Severe fulminant myocarditis causing cardiogenic shock can be a rapidly progressing, life threatening condition. Respiratory syncytial virus (RSV) is a very rare infectious culprit infrequently described in medical literature as a cause of myocarditis, particularly in adults. We present a case of acute fulminant myocarditis in a patient with PCR positive RSV infection requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO).
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/28551066/socially-induced-plasticity-in-sensorimotor-gating-in-the-african-cichlid-fish-astatotilapia-burtoni
#11
Heike Neumeister, Mila Adelman, William Gallagher, Jiangtao Gou, Karin Merrins, Melissa Perkowski, Stephanie Shih, Beth Terranova, Thomas Preuss
Deficits in prepulse inhibition (PPI), social defeat and social withdrawal are hallmark features of several neurological and neuropsychiatric disorders. However, the link between social environment and PPI i.e., the possible role of social defeat in driving PPI plasticity, is far from clear. Here we explored these questions in the African cichlid fish Astatotilapia burtoni, where males exist as two distinct yet reversible phenotypes. In fish communities, DOMs exhibit frequent aggressive and territorial behaviors, threatening and attacking SUBs, which respond either by engaging in fights and fleeing, or by avoiding interaction with DOMs altogether...
May 24, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28550081/randomized-controlled-trial-for-the-effect-of-vitamin-d-supplementation-on-vascular-stiffness-in-ckd
#12
Adeera Levin, Mila Tang, Taylor Perry, Nadia Zalunardo, Monica Beaulieu, Joshua A Dubland, Kelly Zerr, Ognjenka Djurdjev
BACKGROUND AND OBJECTIVES: Vitamin D is implicated in vascular health in CKD. This study compared placebo, calcifediol, and calcitriol treatment with changes in vascular stiffness, BP, proteinuria, mineral metabolism parameters, C-reactive protein, and fibroblast growth factor 23 in patients with stable CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted a double-blind, randomized controlled trial in outpatient CKD clinics in Vancouver, Canada, from February of 2011 to August of 2014, enrolling 119 patients with an eGFR of 15-45 ml/min per 1...
May 26, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28534732/evaluation-of-adaptive-noise-management-technologies-for-school-age-children-with-hearing-loss
#13
Jace Wolfe, Mila Duke, Erin Schafer, Christine Jones, Lori Rakita
BACKGROUND: Children with hearing loss experience significant difficulty understanding speech in noisy and reverberant situations. Adaptive noise management technologies, such as fully adaptive directional microphones and digital noise reduction, have the potential to improve communication in noise for children with hearing aids. However, there are no published studies evaluating the potential benefits children receive from the use of adaptive noise management technologies in simulated real-world environments as well as in daily situations...
May 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28531415/challenges-for-dietitians-in-nutritional-support-of-elderly
#14
Denis Mlakar Mastnak, Mila Terčelj
No abstract text is available yet for this article.
August 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28522107/differences-in-neurohumoral-and-hemodynamic-response-to-prolonged-head-up-tilt-between-patients-with-high-and-normal-standing-norepinephrine-forms-of-postural-orthostatic-tachycardia-syndrome
#15
Luka Crnošija, Magdalena Krbot Skorić, Mila Lovrić, Anamari Junaković, Vladimir Miletić, Rujana Šprljan Alfirev, Antun Pavelić, Ivan Adamec, Mario Habek
OBJECTIVE: To investigate the optimal timing for blood sample collection of catecholamines and the possible correlations between neurohumoral and hemodynamic responses to prolonged head-up tilt (HUT) in postural orthostatic tachycardia syndrome (POTS). METHODS: Nineteen patients underwent a 30-minute, 70° HUT test. Blood samples (norepinephrine (NE), epinephrine and dopamine) were taken in the 10th minute of supine, and 10th, 20th and 30th minutes of HUT. RESULTS: There were no significant differences in the proportion of high and normal standing NE patients in the different time points...
May 11, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28511642/impact-of-a-workplace-sit-less-move-more-program-on-efficiency-related-outcomes-of-office-employees
#16
Anna Puig-Ribera, Judit Bort-Roig, Maria Giné-Garriga, Angel M González-Suárez, Iván Martínez-Lemos, Jesús Fortuño, Joan C Martori, Laura Muñoz-Ortiz, Raimon Milà, Nicholas D Gilson, Jim McKenna
BACKGROUND: Few studies have examined the impact of 'sit less, move more' interventions on workplace performance. This study assessed the short and mid-term impacts of and patterns of change within, a 19-week workplace web-based intervention (Walk@WorkSpain; W@WS; 2010-11) on employees´ presenteeism, mental well-being and lost work performance. METHODS: A site randomised control trial recruited employees at six Spanish university campuses (n = 264; 42 ± 10 years; 171 female), assigned by worksite and campus to an Intervention (IG; used W@WS; n = 129; 87 female) or an active Comparison group (A-CG; pedometer, paper diary and self-reported sitting time; n = 135; 84 female)...
May 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28500750/nausea-and-vomiting-in-children-and-adolescents-receiving-intrathecal-methotrexate-a-prospective-observational-study
#17
Jacqueline Flank, Komail Nadeem, Sheliza Moledina, Mila Khanna, Christina Schindera, Angela Punnett, L Lee Dupuis
BACKGROUND: The prevalence of nausea and vomiting after receipt of intrathecal methotrexate (IT-MTX) in pediatric oncology patients is unknown. METHODS: Patients (4-18 years) about to receive IT-MTX were eligible to participate in this prospective, observational study. Patients received antiemetics as prescribed by their clinical team. Nausea severity (patient-assessed), timing of emetic episodes, and administration of antiemetics were recorded beginning immediately prior to IT-MTX administration, for the next 24 hr (acute phase), and for a maximum of 7 additional days (delayed phase)...
May 13, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28498985/hiv-antibodies-detect-hiv-persistence-and-low-level-viral-replication
#18
Sheila M Keating, Christopher D Pilcher, Vivek Jain, Mila Lebedeva, Dylan Hampton, Mohamed Abdel-Mohsen, Xutao Deng, Gary Murphy, Alex Welte, Shelley N Facente, Frederick Hecht, Steven G Deeks, Satish K Pillai, Michael P Busch
BACKGROUND: HIV antibodies are generated and maintained by ongoing systemic expression of HIV antigen. We investigated whether HIV antibody responses as measured by high-throughput quantitative and qualitative assays could be used to indirectly measure persistent HIV replication in individuals on antiretroviral therapy (ART). METHODS: HIV antibody measurements were made over time on and off suppressive ART and were compared to measures of HIV reservoir size and expression of anti-viral restriction factors...
May 11, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28490270/change-point-detection-for-infinite-horizon-dynamic-treatment-regimes
#19
Yair Goldberg, Moshe Pollak, Alexis Mitelpunkt, Mila Orlovsky, Ahuva Weiss-Meilik, Malka Gorfine
A dynamic treatment regime is a set of decision rules for how to treat a patient at multiple time points. At each time point, a treatment decision is made depending on the patient's medical history up to that point. We consider the infinite-horizon setting in which the number of decision points is very large. Specifically, we consider long trajectories of patients' measurements recorded over time. At each time point, the decision whether to intervene or not is conditional on whether or not there was a change in the patient's trajectory...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/28484521/urinary-podocyte-associated-mrna-levels-correlate-with-proximal-tubule-dysfunction-in-early-diabetic-nephropathy-of-type-2-diabetes-mellitus
#20
Ligia Petrica, Sorin Ursoniu, Florica Gadalean, Adrian Vlad, Gheorghe Gluhovschi, Victor Dumitrascu, Daliborca Vlad, Cristina Gluhovschi, Silvia Velciov, Flaviu Bob, Petru Matusz, Oana Milas, Alina Secara, Anca Simulescu, Roxana Popescu
AIM: The study assessed mRNA expression of podocyte-associated molecules in urinary sediments of patients with type 2 diabetes mellitus (DM) in relation to urinary podocytes, biomarkers of podocyte injury and of proximal tubule (PT) dysfunction. METHODS: A total of 76 patients with type 2 DM and 20 healthy subjects were enrolled in a cross-sectional study, and assessed concerning urinary podocytes, urinary mRNA of podocyte-associated genes, urinary biomarkers of podocyte damage and of PT dysfunction...
2017: Diabetology & Metabolic Syndrome
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