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Sterile packaging

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https://www.readbyqxmd.com/read/28647423/sterilizing-service-unit-packing-area-to-glove-or-regular-hand-hygiene-that-is-the-question
#1
Dayane de Melo Costa, Lillian Kelly de Oliveira Lopes, Anaclara Ferreira Veiga Tipple, Roel Beltran Castillo, Honghua Hu, Anand Kumar Deva, Karen Vickery
BACKGROUND: During functionality testing and packaging of reusable surgical instruments (RSI) for sterilisation, instruments are frequently touched. Considering the lack of standards relating to hand hygiene frequency and use of gloves in the sterilising service unit packing area, we aimed to determine the effect of hand hygiene and glove use on maintenance of RSI cleanliness. METHODS: Following manual and automated cleaning, Halsted-mosquito forceps were assessed for adenosine triphosphate (ATP), protein and microbial contamination after handling with gloved and ungloved but washed hands utilising an ATP surface swab test, bicinchoninic acid assay, and standard culture plate/broth, respectively...
June 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28616079/surgical-site-infection-and-its-associated-factors-following-cesarean-section-a-cross-sectional-study-from-a-public-hospital-in-ethiopia
#2
Kelemu Abebe Gelaw, Amlaku Mulat Aweke, Feleke Hailemichael Astawesegn, Birhanu Wondimeneh Demissie, Liknaw Bewket Zeleke
BACKGROUND: A cesarean section is a surgical procedure in which incisions are made through a woman's abdomen and uterus to deliver her baby. Surgical site infections are a common surgical complication among patients delivered with cesarean section. Further it caused to increase maternal morbidity, stay of hospital and the cost of treatment. METHODS: Hospital based cross-sectional study was conducted to assess the magnitude of surgical site infection following cesarean Site Infections and its associated factors at Lemlem Karl hospital July 1, 2013 to June 30, 2016...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28577503/ph-triggered-controlled-drug-delivery-from-contact-lenses-addressing-the-challenges-of-drug-leaching-during-sterilization-and-storage
#3
Furqan A Maulvi, Harsh H Choksi, Ankita R Desai, Akanksha S Patel, Ketan M Ranch, Bhavin A Vyas, Dinesh O Shah
In the present work a novel cyclosporine-loaded Eudragit S100 (pH-sensitive) nanoparticles-laden contact lenses were designed to provide sustained release of cyclosporine at therapeutic rates, without leaching of drug during sterilization and storage period (shelf life). The nanoparticles were prepared by Quasi-emulsion solvent diffusion technique using different weight ratios of cyclosporine to Eudragit S100. The contact lenses with direct drug entrapment were also fabricated (DL-50) for comparison. The percentage swelling and optical transparency of nanoparticles-laden contact lenses were improved in comparison to DL-50 lenses...
May 27, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28571138/bacterial-contamination-of-adult-house-flies-musca-domestica-and-sensitivity-of-these-bacteria-to-various-antibiotics-captured-from-hamadan-city-iran
#4
Mansour Nazari, Tahereh Mehrabi, Seyed Mostafa Hosseini, Mohammad Yousef Alikhani
INTRODUCTION: House flies (Musca domestica) have been known as a mechanical vector in spreading infectious diseases such as cholera, shigellosis, salmonellosis and skin infections. AIM: To investigate the bacterial contaminations of house flies and determine the resistance of these bacteria against various antibiotics. MATERIALS AND METHODS: An analytical descriptive cross- sectional study was conducted. The study was performed from July to September 2015 in Hamadan University of Medical Sciences, Hamadan, Iran...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28511502/comparative-evaluation-of-three-herbal-solutions-on-the-disinfection-of-guttapercha-cones-an-in-vitro-study
#5
Pratap Kumar Mukka, Samba Shiva Rao Pola, Nanda Kumar Kommineni, Mayuri Sailaja Pachalla, Anand Ramtheerth Karne, Karthik Labishetty, Supriya Kommineni, Praveen Chilakabathini
INTRODUCTION: Guttapercha (GP) cones are usually supplied in aseptic, sealed packages from the manufacturers, but once exposed to the dental office environment or even by handling; they can be contaminated by a number of microorganisms. Supplementary decontamination of GP cones is critical. As they cannot be sterilized by moist or dry heat, cold sterilization, using disinfectants should be used. AIM: The aim of the study was to evaluate rapid, reliable, convenient and effective method of disinfection of GP cones using readily available herbal solutions such as Aloevera Juice, Amla Juice and Pancha Tulsi...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28504125/preparation-of-chitosan-tio2-composite-film-with-efficient-antimicrobial-activities-under-visible-light-for-food-packaging-applications
#6
Xiaodong Zhang, Gang Xiao, Yaoqiang Wang, Yan Zhao, Haijia Su, Tianwei Tan
By incorporation of TiO2 nano-powder in chitosan, a chitosan-TiO2 composite film was prepared with efficient antimicrobial activity against food-borne pathogenic microbes and expected to be a promising food packaging material. Scanning electron microscopy analysis showed that the TiO2 nano-powder was successfully and uniformly dispersed into the chitosan matrix. TiO2 addition led to enhanced hydrophilicity, to better mechanical properties, and to decreased light transmittance in visible light region of the composite film...
August 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28500861/overview-of-high-risk-medical-device-recalls-in%C3%A2-obstetrics%C3%A2-and-gynecology-from-2002-through-2016-%C3%A2-implications-for-device-safety
#7
Timothy M Janetos, Comeron W Ghobadi, Shuai Xu, Jessica R Walter
The field of women's health has endured numerous recent controversies involving medical devices such as pelvic meshes, laparoscopic morcellators, and a hysteroscopic sterilization device. With the recent passage of the 21st Century Cures Act, new legislation will change how the Food and Drug Administration regulates medical devices. Given these controversies and new changes, we investigated high-risk, class I recalls in women's health from 2002 through 2016. Class I recalls for medical devices are defined by the Food and Drug Administration as the most serious recall events and are designated for situations when there is a reasonable probability of serious adverse health consequences or death...
April 29, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28475151/antimicrobial-optical-and-mechanical-properties-of-chitosan-starch-films-with-natural-extracts
#8
Jessica I Lozano-Navarro, Nancy P Díaz-Zavala, Carlos Velasco-Santos, Ana L Martínez-Hernández, Beatriz I Tijerina-Ramos, Margarita García-Hernández, José L Rivera-Armenta, Ulises Páramo-García, Adriana I Reyes-de la Torre
Natural extracts possess several kinds of antioxidants (anthocyanins, betalains, thymol, carvacrol, and resveratrol) that have also demonstrated antimicrobial properties. In order to study these properties, extracts from cranberry, blueberry, beetroot, pomegranate, oregano, pitaya, and resveratrol (from grapes) were obtained. Growth inhibition tests of mesophilic aerobes, coliforms, and fungi were conducted in films prepared from the extracts in accordance with Mexican Official Norms (NOM). Optical properties such as transparency and opacity, mechanical properties, and pH were also analyzed in these materials...
May 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28471056/essential-oil-bioactive-fibrous-membranes-prepared-via-coaxial-electrospinning
#9
Zhi-Cheng Yao, Si-Cong Chen, Zeeshan Ahmad, Jie Huang, Ming-Wei Chang, Jing-Song Li
A novel antimicrobial composite material was prepared by encapsulating orange essential oil (OEO) in zein prolamine (ZP) via the coaxial electrospinning (ES) technique. By manipulating process parameters, the morphological features of ZP/OEO fibers were modulated. Fine fibers with diameters ranging from 0.7 to 2.3 μm were obtained by regulating ZP solution concentration and process parameters during the ES process. Optimal loading capacity (LC) and encapsulation efficiency (EE) of OEO in fibrous ZP mats were determined to be 22...
June 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28447477/simultaneous-visualization-of-hydrogen-peroxide-and-water-concentrations-using-photofragmentation-laser-induced-fluorescence
#10
Kajsa Larsson, Marcus Aldén, Joakim Bood
A concept based on photofragmentation laser-induced fluorescence (PFLIF) is for the first time demonstrated for simultaneous detection of hydrogen peroxide (H2O2) and water (H2O) vapor in various mixtures containing the two constituents in a bath of argon gas. A photolysis laser pulse at 248 nm dissociates H2O2 into OH fragments, whereupon a probe pulse, delayed 100 ns and tuned to an absorption line in the A(2)Σ(+) (v = 1) ← X(2)Π(v = 0) band of OH near 282 nm, induces fluorescence. The total OH fluorescence reflects the H2O2 concentration, while its spectral shape is utilized to determine the H2O concentration via a model predicting the ratio between the fluorescence intensities of the A(2)Σ(+) (v = 1) → X(2)Π(v = 1) and the A(2)Σ(+) (v = 0) → X(2)Π(v = 0) bands...
January 1, 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28377648/comparison-of-antimicrobial-efficacy-of-diode-laser-triphala-and-sodium-hypochlorite-in-primary-root-canals-a-randomized-controlled-trial
#11
Seby Thomas, Sharath Asokan, Baby John, Geetha Priya, S Kumar
AIM: To evaluate the antimicrobial efficacy of diode laser, triphala, and sodium hypochlorite (NaOCl) against Enterococc-cus faecalis contaminated primary root canals. MATERIALS AND METHODS: Forty-nine single-rooted human primary teeth were reduced up to cemento-enamel junction and biomechanically prepared. After sterilization, five teeth were selected as negative controls and remaining teeth were inoculated with E. faecalis. The teeth were then randomly divided into four groups...
January 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28339392/stability-of-ribavirin-for-inhalation-packaged-in-syringes-or-glass-vials-when-stored-frozen-refrigerated-and-at-room-temperature
#12
COMPARATIVE STUDY
Bayli Larson, Lane R Bushman, Matthew L Casciano, Alan R Oldland, Jennifer J Kiser, Tyree H Kiser
The primary aim of this study was to investigate ribavirin solution for inhalation stability under three different conditions (frozen, refrigerated, room temperature) over a 45-day period. A ribavirin 6000-mg vial was reconstituted with 90 mL of Sterile Water for Injection per the package insert to yield a concentration of approximately 67 mg/mL. The solution was then placed in either syringes or empty glass vials and stored in the freezer (-20°C), in the refrigerator (~0°C to 4°C), or at room temperature (~20°C to 25°C)...
November 2016: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28336072/microneedle-enzyme-sensor-arrays-for-continuous-in-vivo-monitoring
#13
Anthony E G Cass, Sanjiv Sharma
Microneedle enzyme sensors by virtue of their minimally invasive and hence pain-free penetration of skin allow for the measurement of metabolites, biomarkers, and drugs in the interstitial fluid that bathes the dermal tissue. Such devices if they are to be adopted widely into clinical practice need to be capable of delivering reliable measurements over extended periods of time (days) and to be fabricated by low-cost, scalable methods. Using injection molding of the base structures in polycarbonate, metal film deposition by sputtering and enzyme immobilization by electrodeposition can meet these requirements...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28333657/current-perspectives-on-the-syringe-delivery-system
#14
Michael J Akers
An article on the topic of sterile product packaging and delivery systems was published in the November/December 2015 issue of the International Journal of Pharmaceutical Compounding. This article expands the discussion on the syringe packaging system and provides more detail about the history, changes, challenges, and use of syringes in the compounding pharmacy.
May 2016: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28331535/rosettr-protocol-and-software-for-seedling-area-and-growth-analysis
#15
Filipa Tomé, Karel Jansseune, Bernadette Saey, Jack Grundy, Korneel Vandenbroucke, Matthew A Hannah, Henning Redestig
BACKGROUND: Growth is an important parameter to consider when studying the impact of treatments or mutations on plant physiology. Leaf area and growth rates can be estimated efficiently from images of plants, but the experiment setup, image analysis, and statistical evaluation can be laborious, often requiring substantial manual effort and programming skills. RESULTS: Here we present rosettR, a non-destructive and high-throughput phenotyping protocol for the measurement of total rosette area of seedlings grown in plates in sterile conditions...
2017: Plant Methods
https://www.readbyqxmd.com/read/28271926/listeria-monocytogenes-internalizes-in-romaine-lettuce-grown-in-greenhouse-conditions
#16
Archana G Shenoy, Haley F Oliver, Amanda J Deering
Listeria monocytogenes has been implicated in a number of outbreaks involving fresh produce, including an outbreak in 2016 resulting from contaminated packaged salads. The persistence and internalization potential of L. monocytogenes in romaine lettuce was evaluated, and the persistence of two L. monocytogenes strains was assessed on three romaine lettuce cultivars. Seeds were germinated, and plants grown in three soil types (i.e., standard potting mix, autoclaved potting mix, and top soil) and sterile soft-top agar for up to 21 days...
April 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28184276/segregation-for-reduction-of-regulated-medical-waste-in-the-operating-room-a-case-report
#17
Helen Ki Shinn, Youngyoen Hwang, Byung-Gun Kim, Chunwoo Yang, WonJu Na, Jang-Ho Song, Hyun Kyoung Lim
One-third of all hospital-regulated medical waste (RMW) comes from the operating room (OR), and it considerably consists of disposable packaging and wrapping materials for the sterilization of surgical instruments. This study sought to identify the amount and type of waste produced by ORs in order to reduce the RMW so as to achieve environmentally-friendly waste management in the OR. We performed an initial waste segregation of 4 total knee replacement arthroplasties (TKRAs) and 1 total hip replacement arthroplasty, and later of 1 extra TKRA, 1 laparoscopic anterior resection of the colon, and 1 pelviscopy (with radical vaginal hysterectomy), performed at our OR...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28163377/destruction-of-biological-particles-using-non-thermal-plasma
#18
REVIEW
Akira Mizuno
Mechanism of inactivation of bio-particles exposed to non-thermal plasma (NTP), namely, dielectric barrier discharge (DBD), and plasma jet (PJ), has been studied using E. coli, B. subtilis spore, S. cerevisiae and bacteriophages. States of different biological components were monitored during the course of inactivation. Analysis of green fluorescent protein, GFP, introduced into E. coli. or B. subtiles spore cells proved that radicals generated by NTP penetrate into microbes, destroying the cell membrane and finally damage the genes...
January 2017: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/28119764/relevant-in-vitro-predictors-of-human-acellular-dermal-matrix-associated-inflammation-and-capsule-formation-in-a-nonhuman-primate-subcutaneous-tissue-expander-model
#19
Maryellen Sandor, Patrick Leamy, Pearl Assan, Amardeep Hoonjan, Li-Ting Huang, Marianne Edwards, Wenqi Zuo, Hui Li, Hui Xu
Objective: Benchtop methods were evaluated for preclinical inflammation/capsule formation correlation following implantation of human acellular dermal matrices. Methods: Dermal matrices were compared with native dermis for structure (histology, scanning electron microscopy), collagen solubility (hydroxyproline), enzymatic susceptibility (collagenase), and thermal stability (differential scanning calorimetry). Results were compared with implantation outcomes in a primate tissue expander model. Results: Native dermis, electron beam-sterilized, and freeze-dried human acellular dermal matrices had equivalent morphology, acid-soluble collagen (60...
2017: Eplasty
https://www.readbyqxmd.com/read/28118825/optimization-of-mosquito-egg-production-under-mass-rearing-setting-effects-of-cage-volume-blood-meal-source-and-adult-population-density-for-the-malaria-vector-anopheles-arabiensis
#20
Wadaka Mamai, Nanwintoum S Bimbile-Somda, Hamidou Maiga, José Guillermo Juarez, Zaynab A I Muosa, Adel Barakat Ali, Rosemary Susan Lees, Jeremie R L Gilles
BACKGROUND: Anopheles arabiensis is one of the major malaria vectors that put millions of people in endemic countries at risk. Mass-rearing of this mosquito is crucial for strategies that use sterile insect technique to suppress vector populations. The sterile insect technique (SIT) package for this mosquito species is being developed by the Insect Pest Control Subprogramme of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture. To improve mass-rearing outcomes for An...
January 24, 2017: Malaria Journal
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