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Sterile barrier

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https://www.readbyqxmd.com/read/27924201/central-line-associated-bloodstream-infections-in-the-intensive-care-unit-importance-of-the-care-bundle
#1
Aynur Atilla, Zahide Doğanay, Hale Kefeli Çelik, Leman Tomak, Özgür Günal, S Sırrı Kılıç
BACKGROUND: The importance and efficacy of a care bundle for preventing central line-associated bloodstream infections (CLABSIs) and infectious complications related to placing a central venous catheter (CVC) in patients in the intensive care unit (ICU). METHODS: A care bundle was implemented from July 2013 to June 2014 in a medical ICU and surgical ICU. Data were divided into three periods: the prior period (July 2012-June 2013), the intervention period (July 2013-June 2014; first and second periods), and the post-intervention period (July 2014-December 2014; third period)...
December 2016: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/27923272/elimination-of-diazinon-insecticide-from-cucumber-surface-by-atmospheric-pressure-air-dielectric-barrier-discharge-plasma
#2
Naghme Dorraki, Vahideh Mahdavi, Hamid Ghomi, Alireza Ghasempour
The food industry is in a constant search for new technologies to improve the commercial sterilization process of agricultural commodities. Plasma treatment may offer a novel and efficient method for pesticide removal from agricultural product surfaces. To study the proposed technique of plasma food treatment, the degradation behavior of diazinon insecticide by air-dielectric barrier discharge (DBD) plasma was investigated. The authors studied the effect of different plasma powers and treatment times on pesticide concentration in liquid form and coated on the surface of cucumbers, where the diazinon residue was analyzed with mass spectroscopy gas chromatography...
December 6, 2016: Biointerphases
https://www.readbyqxmd.com/read/27907138/barriers-to-modern-contraceptive-use-in-kinshasa-drc
#3
Mbadu Muanda, Parfait Gahungu Ndongo, Leah D Taub, Jane T Bertrand
Recent research from Kinshasa, DRC, has shown that only one in five married women uses modern contraception; over one quarter have an unmet need for family planning; and almost 400 health facilities across Kinshasa report that they provide modern contraception. This study addresses the question: with reasonable physical access and relatively high unmet need, why is modern contraceptive prevalence so low? To this end, the research team conducted 6 focus groups of women (non-users of any method, users of traditional methods, and users of modern methods) and 4 of husbands (of users of traditional methods and in non-user unions) in health zones with relatively strong physical access to FP services...
2016: PloS One
https://www.readbyqxmd.com/read/27902340/viral-bacterial-interactions-in-the-respiratory-tract
#4
Carla Bellinghausen, Gernot Gu Rohde, Paul Hm Savelkoul, Emiel Fm Wouters, Frank Rm Stassen
In the respiratory tract, viruses and bacteria can interact on multiple levels. It is well known that respiratory viruses, particularly influenza viruses, increase the susceptibility to secondary bacterial infections. Numerous mechanisms, including compromised physical and immunological barriers, and changes in the microenvironment have hereby been shown to contribute to the development of secondary bacterial infections. In contrast, our understanding of how bacteria shape a response to subsequent viral infection is still limited...
October 18, 2016: Journal of General Virology
https://www.readbyqxmd.com/read/27832813/the-need-for-maximal-sterile-barrier-precaution-in-routine-interventional-coronary-procedures-microbiology-analysis
#5
Avi Peretz, Fabio Kuzniec, Diab Ganem, Nabeeh Salman, Dahud Qarawani, Offer Amir
BACKGROUND: Maximal sterile barrier precautions (MSBP) including head coverings and face masks are advocated for use in invasive procedures, including coronary interventions. The rationale for MSBP assumes it is an obligatory measure for infection prevention. However, in many coronary catheterization laboratories, head coverings/face masks are not used in daily practice. This study prospectively evaluated the potential hazards of not routinely using head coverings/face masks in routine coronary interventions...
November 10, 2016: European Journal of Medical Research
https://www.readbyqxmd.com/read/27823943/patient-provider-conversations-about-sterilization-a-qualitative-analysis
#6
Katrina Kimport, Christine Dehlendorf, Sonya Borrero
OBJECTIVES: Although female sterilization is the second most commonly used contraceptive method in the US, research suggests that providers may serve as barriers to desired sterilization. STUDY DESIGN: We conducted a modified grounded theory analysis of audio-recorded contraceptive counseling visits with 52 women who specified on a previsit survey that they wanted no future children and a supplemental analysis of visits with 14 women who wanted or were unsure about future children in which sterilization was mentioned...
November 4, 2016: Contraception
https://www.readbyqxmd.com/read/27818131/threats-to-reproductive-health-care-time-for-obstetrician-gynecologists-to-get-involved
#7
David L Eisenberg, V C Leslie
To be healthy, support their families, and be productive members of their communities, women must have access to comprehensive reproductive health services including treatment of miscarriage and ectopic pregnancy and access to abortion, sterilization, and other contraceptive methods. However, in the United States, hospitals and legislative bodies are erecting barriers and limiting access to these basic health care services. These barriers are caused by factors such as hospital mergers (specifically those that are religiously affiliated); federal, state, and local legislation; hospital policies; and business-related decisions are threatening reproductive health care...
November 4, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27812146/differences-in-the-access-to-sterilization-between-women-living-and-not-living-with-hiv-results-from-the-genih-study-brazil
#8
Regina Maria Barbosa, Cristiane da Silva Cabral, Tania di Giacomo do Lago, Adriana de Araujo Pinho
BACKGROUND: In many countries, young women of reproductive age have been especially affected by the HIV epidemic, which have fostered research to better understand how HIV infection influences and shapes women´s fertility and reproductive and sexual decisions. In Brazil, few studies have focused on the impact of the HIV epidemic on contraceptive choices among women living with HIV (WLHIV). OBJECTIVE: This study evaluates the impact HIV infection may have in the access to female sterilization in Brazil, using a time-to-event analysis...
2016: PloS One
https://www.readbyqxmd.com/read/27806056/cross-mating-compatibility-and-competitiveness-among-aedes-albopictus-strains-from-distinct-geographic-origins-implications-for-future-application-of-sit-programs-in-the-south-west-indian-ocean-islands
#9
David Damiens, Cyrille Lebon, David A Wilkinson, Damien Dijoux-Millet, Gilbert Le Goff, Ambicadutt Bheecarry, Louis Clément Gouagna
The production of large numbers of males needed for a sustainable sterile insect technique (SIT) control program requires significant developmental and operational costs. This may constitute a significant economic barrier to the installation of large scale rearing facilities in countries that are undergoing a transition from being largely dependent on insecticide use to be in a position to integrate the SIT against Aedes albopictus. Alternative options available for those countries could be to rely on outsourcing of sterile males from a foreign supplier, or for one centralised facility to produce mosquitoes for several countries, thus increasing the efficiency of the mass-rearing effort...
2016: PloS One
https://www.readbyqxmd.com/read/27797468/host-cell-interactions-are-a-significant-barrier-to-the-clinical-utility-of-peptide-antibiotics
#10
Charles G Starr, Jing He, William C Wimley
Despite longstanding promise and many known examples, antimicrobial peptides (AMPs) have failed, thus far, to impact human medicine. Based on the physical chemistry and mechanism of action of AMPs, we hypothesized that host cell interactions could contribute to loss of activity in vivo where host cells are highly concentrated. To test this idea, we characterized AMP activity in the presence of human red blood cells (RBC). Indeed, we show that most of a representative set of natural and synthetic AMPs tested are significantly inhibited by preincubation with host cells, and would be effectively inactive at physiological cell density...
October 31, 2016: ACS Chemical Biology
https://www.readbyqxmd.com/read/27789359/lipid-nanoparticles-sln-nlc-overcoming-the-anatomical-and-physiological-barriers-of-the-eye-part-ii-ocular-drug-loaded-lipid-nanoparticles
#11
E Sánchez-López, M Espina, S Doktorovova, E B Souto, M L García
In the recent decades, various controlled delivery systems have been introduced with the aim to improve solubility, stability and bioavailability of poorly absorbed drugs. Among all, lipid nanoparticles gather interesting properties as drug or gene delivery carriers. These systems, composed either of solid lipids (SLN) or of solid and liquid lipids (NLC) stabilized with surfactants, combine the advantages of other colloidal particles such as polymeric nanoparticles, fat emulsions and liposomes avoiding their main disadvantages...
October 24, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27789356/applications-of-lipid-nanoparticles-in-gene-therapy
#12
Ana Del Pozo-Rodríguez, María Ángeles Solinís, Alicia Rodríguez-Gascón
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have been recognized, among the large number of non-viral vectors for gene transfection, as an effective and safety alternative to potentially treat both genetic and not genetic diseases. A key feature is the possibility to be designed to overcome the numerous challenges for successful gene delivery. Lipid nanoparticles (LNs) are able to overcome the main biological barriers for cell transfection, including degradation by nucleases, cell internalization intracellular trafficking, and selectively targeting to a specific cell type...
December 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27751177/successful-treatment-with-fecal-microbiota-transplantation-in-patients-with-multiple-organ-dysfunction-syndrome-and-diarrhea-following-severe-sepsis
#13
Yanling Wei, Jun Yang, Jun Wang, Yang Yang, Juan Huang, Hao Gong, Hongli Cui, Dongfeng Chen
BACKGROUND: The dysbiosis of intestinal microbiota plays an important role in the development of gut-derived infections, making it a potential therapeutic target against multiple organ dysfunction syndrome (MODS) after sepsis. However, the effectiveness of fecal microbiota transplantation (FMT) in treating this disease has been rarely investigated. METHODS: Two male patients, a 65-year-old and an 84-year-old, were initially diagnosed with cerebellar hemorrhage and cerebral infarction, respectively, after admission...
October 18, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27749446/tectonic-descemet-stripping-automated-endothelial-keratoplasty-for-the-management-of-sterile-corneal-perforations-in-decompensated-corneas
#14
Yoav Nahum, Irit Bahar, Massimo Busin
PURPOSE: To report the use of Descemet stripping automated endothelial keratoplasty (DSAEK) for treatment of sterile corneal perforations accompanying endothelial decompensation. METHODS: In this multicenter interventional case series, we reviewed the medical records of all tectonic DSAEK surgeries performed at Villa Serena-Villa Igea private Hospitals (Forlì, Italy) and Rabin Medical Center (Petach Tikva, Israel) between January 2014 and March 2016. RESULTS: Three patients with endothelial decompensation and sterile corneal perforation (n = 2) or impending corneal perforation (n = 1) underwent DSAEK between 2014 and 2015 at Villa Igea Hospital, Forlì, Italy, and Rabin Medical Center, Petach Tikva, Israel...
October 5, 2016: Cornea
https://www.readbyqxmd.com/read/27729683/usp-800-key-considerations-and-changes-for-health-systems
#15
EDITORIAL
Priya Sahadeo, Robert J Weber
On March 28, 2014, The United States Pharmacopeia and The National Formulary (USP-NF) published USP General Chapter <800> Hazardous Drugs-Handling in Healthcare Settings, as open for public comment in the USP Pharmacopeial Forum (PF) 40(3). Pharmacy directors must be proactive in understanding the impact that USP <800> will have on their processes for preparing sterile products. USP General Chapter <797> pertains to the compounding of both hazardous and nonhazardous drugs. USP <800> serves as a new standard to guide the handling of hazardous drugs in order to protect patients, health care personnel, and the environment...
November 2015: Hospital Pharmacy
https://www.readbyqxmd.com/read/27727097/ileus-is-a-predictor-of-local-infection-in-patients-with-acute-necrotizing-pancreatitis
#16
Robert A Moran, Niloofar Y Jalaly, Ayesha Kamal, Sandesh Rao, Robert Klapheke, Theodore W James, Swetha Kambhampati, Martin A Makary, Kenzo Hirose, Vivek Kumbhari, Ellen M Stein, Mouen A Khashab, Anne Marie Lennon, Anthony N Kalloo, Atif Zaheer, Ruben Hernaez, Vikesh K Singh
BACKGROUND & OBJECTIVES: Infected pancreatic necrosis (IPN) is associated with increased morbidity and mortality. Gut barrier dysfunction has been shown to increase the risk of bacterial translocation from the gut into the pancreatic bed. The primary aim of the study is to evaluate if ileus, a clinical marker of gut barrier dysfunction, can predict the development of IPN. METHODS: A retrospective cohort study of patients with necrotizing pancreatitis (NP) was conducted from 2000 to 2014...
November 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/27717553/new-developments-in-long-acting-reversible-contraception-the-promise-of-intrauterine-devices-and-implants-to-improve-family-planning-services
#17
David K Turok, Lori M Gawron, Samantha Lawson
After decades of having the developed world's highest rates of unintended pregnancy, the United States finally shows signs of improvement. This progress is likely due in large part to increased use of highly effective long-acting reversible methods of contraception. These methods can be placed and do not require any maintenance to provide years of contraception as effective as sterilization. Upon removal, fertility returns to baseline rates. This article addresses advances in both software-improved use and elimination of barriers to provide these methods; and hardware-novel delivery systems and devices...
October 4, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27659038/female-adult-aedes-albopictus-suppression-by-wolbachia-infected-male-mosquitoes
#18
James W Mains, Corey L Brelsfoard, Robert I Rose, Stephen L Dobson
Dengue, chikungunya and zika viruses are pathogens with an increasing global impact. In the absence of an approved vaccine or therapy, their management relies on controlling the mosquito vectors. But traditional controls are inadequate, and the range of invasive species such as Aedes albopictus (Asian Tiger Mosquito) is expanding. Genetically modified mosquitoes are being tested, but their use has encountered regulatory barriers and public opposition in some countries. Wolbachia bacteria can cause a form of conditional sterility, which can provide an alternative to genetic modification or irradiation...
September 23, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27648239/both-morph-and-species-dependent-asymmetries-affect-reproductive-barriers-between-heterostylous-species
#19
Barbara Keller, Jurriaan M de Vos, Alexander N Schmidt-Lebuhn, James D Thomson, Elena Conti
The interaction between floral traits and reproductive isolation is crucial to explaining the extraordinary diversity of angiosperms. Heterostyly, a complex floral polymorphism that optimizes outcrossing, evolved repeatedly and has been shown to accelerate diversification in primroses, yet its potential influence on isolating mechanisms remains unexplored. Furthermore, the relative contribution of pre- versus postmating barriers to reproductive isolation is still debated. No experimental study has yet evaluated the possible effects of heterostyly on pre- and postmating reproductive mechanisms...
September 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/27570140/request-and-fulfillment-of-postpartum-tubal-ligation-in-patients-after-high-risk-pregnancy
#20
Alexandra Albanese, Maureen French, Dana R Gossett
OBJECTIVE: Female sterilization is one of the most prevalent methods of contraception in the United States. Prior studies have shown that nearly half of postpartum tubal ligation (PPTL) requests go unfulfilled. This study seeks to establish whether obstetric or medical risk status influences patients' request for or subsequent completion of PPTL. METHODS: This study was a retrospective cohort study of women delivering at a university hospital in 2009-2010 who received prenatal care in the faculty and resident clinics...
August 26, 2016: Contraception
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