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Sterile barrier

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https://www.readbyqxmd.com/read/29771940/unplanned-pregnancies-and-contraceptive-use-among-hiv-positive-women-in-care
#1
Madeline Y Sutton, Wen Zhou, Emma L Frazier
Among 230,360 women with diagnosed HIV in the United States (U.S.), ~ 8,500 give birth annually, and unplanned pregnancies (as with HIV-negative women) are prevalent. However, unplanned pregnancies and contraceptive use among HIV-positive women have been understudied. To examine unplanned pregnancies and contraceptive use among HIV-positive women, we used 2013-2014 data from the Medical Monitoring Project (MMP), an HIV surveillance system that produces national estimates for HIV-positive adults in care in the U...
2018: PloS One
https://www.readbyqxmd.com/read/29771901/achilles-tenotomy-as-an-office-procedure-and-current-practising-trends-among-new-zealand-orthopaedic-surgeons
#2
Lewis Agius, Angus Wickham, Cameron Walker, Joshua Knudsen
BACKGROUND: Percutaneous Achilles tenotomy (PAT) is performed during the final phase of casting with Ponseti method. Several settings have been proposed as venues for this procedure, however it is increasingly being performed in theatre under a general anaesthetic (GA). General anaesthesia, however, is expensive and not without risks. The purpose of the present study was to compare results of outpatient releases to theatre releases, and assess current practising trends among orthopaedic surgeons...
May 18, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29762868/candidemia-in-children-epidemiology-prevention-and-management
#3
REVIEW
Elpis Mantadakis, Zoe Dorothea Pana, Theoklis Zaoutis
Candidemia is the leading cause of invasive fungal infections in hospitalized children. The highest rates of candidemia have been recorded in neonates and infants <1 year of age. Candidemia is more frequent in neonates and young infants than in adults, and is associated with better clinical outcomes, but higher inpatient costs. Over the last 10 years, a declining trend has been noted in the incidence of pediatric candidemia in the US and elsewhere due to the hospital-wide implementation of central-line insertion and maintenance bundles that emphasize full sterile barrier precautions, chlorhexidine skin preparation during line insertion, meticulous site and tubing care, and daily discussion of catheter necessity...
May 15, 2018: Mycoses
https://www.readbyqxmd.com/read/29750600/exploring-respiratory-protection-practices-for-prominent-hazards-in-healthcare-settings
#4
Kerri Wizner, Mahiyar Nasarwanji, Edward Fisher, Andrea L Steege, James M Boiano
The use of respiratory protection, an important component of personal protective equipment (PPE) in healthcare, is dependent on the hazard and environmental conditions in the workplace. This requires the employer and healthcare worker (HCW) to be knowledgeable about potential exposures and their respective protective measures. However, the use of respirators is inconsistent in healthcare settings, potentially putting HCWs at risk for illness or injury. To better understand respirator use, barriers, and influences, the National Institute for Occupational Safety and Health (NIOSH) Health and Safety Practices Survey of Healthcare Workers provided an opportunity to examine self-reported use of respirators and surgical masks for targeted hazards...
May 11, 2018: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/29722362/focused-ultrasound-with-microbubbles-induces-sterile-inflammatory-response-proportional-to-the-blood-brain-barrier-opening-attention-to-experimental-conditions
#5
EDITORIAL
Zsofia I Kovacs, Scott R Burks, Joseph A Frank
This editorial highlights the findings of McMahon [1] and demonstrates the need for careful attention to experimental conditions that influence microbubble concentration and pharmacokinetics contributed to focused ultrasound-induced blood brain barrier opening and sterile inflammation.
2018: Theranostics
https://www.readbyqxmd.com/read/29703229/impact-of-an-integrated-control-campaign-on-tsetse-populations-in-burkina-faso
#6
Lassané Percoma, Adama Sow, Soumaïla Pagabeleguem, Ahmadou H Dicko, Oumarou Serdebéogo, Mariam Ouédraogo, Jean-Baptiste Rayaissé, Jérémy Bouyer, Adrien M G Belem, Issa Sidibé
BACKGROUND: Tsetse flies are the sole vectors of human and animal trypanosomosis. In Burkina Faso, a project aiming to create zones free of tsetse flies and trypanosomosis was executed from June 2006 to December 2013. After the determination of tsetse distribution in the intervention area from December 2007 to November 2008, the control campaign was launched in November 2009 and ended in December 2013. The goal was to eliminate tsetse flies from 40,000 km2 of area, through an integrated control campaign including insecticide targets, traps and cattle, sequential aerial treatment (SAT) and the mass treatment of livestock using trypanocides...
April 27, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29692350/the-evolution-of-polymorphic-hybrid-incompatibilities-in-house-mice
#7
Erica L Larson, Dan Vanderpool, Brice A J Sarver, Colin Callahan, Sara Keeble, Lorraine P Provencio, Michael D Kessler, Vanessa Stewart, Erin Nordquist, Matthew D Dean, Jeffrey M Good
Resolving the mechanistic and genetic bases of reproductive barriers between species is essential to understanding the evolutionary forces that shape speciation. Intrinsic hybrid incompatibilities are often treated as fixed between species, yet there can be considerable variation in the strength of reproductive isolation between populations. The extent and causes of this variation remain poorly understood in most systems. We investigated the genetic basis of variable hybrid male sterility (HMS) between two recently diverged subspecies of house mice, Mus musculus domesticus and M...
April 24, 2018: Genetics
https://www.readbyqxmd.com/read/29691912/effect-of-hybridization-with-genome-exclusion-on-extinction-risk
#8
Claudio S Quilodrán, Mathias Currat, Juan I Montoya-Burgos
Human-induced habitat changes may lead to the breakdown of reproductive barriers between distantly related species. This phenomenon may result in fertile first-generation hybrids (F1 ) that exclude the genome of one parental species during gametogenesis, thus disabling introgression. The species extinction risk associated with hybridization with genome exclusion is largely underappreciated because the phenomenon produces only F1 hybrid phenotype, leading to the misconception that hybrids are sterile and potentially of minor conservation concern...
April 24, 2018: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/29685519/contraception-in-dogs-and-cats
#9
REVIEW
Cheryl S Asa
Although surgical sterilization is the most common approach to reproductive management of dogs and cats in North America and many other places, there is growing interest in nonsurgical and reversible methods. This review summarizes the methods currently available for use as reversible contraception in dogs and cats, along with cautions about reported side effects. The products covered include synthetic steroid hormones, peptide hormone agonists, vaccines, and a barrier method.
April 20, 2018: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/29685108/population-structure-genetic-diversity-and-downy-mildew-resistance-among-ocimum-species-germplasm
#10
Robert M Pyne, Josh A Honig, Jennifer Vaiciunas, Christian A Wyenandt, James E Simon
BACKGROUND: The basil (Ocimum spp.) genus maintains a rich diversity of phenotypes and aromatic volatiles through natural and artificial outcrossing. Characterization of population structure and genetic diversity among a representative sample of this genus is severely lacking. Absence of such information has slowed breeding efforts and the development of sweet basil (Ocimum basilicum L.) with resistance to the worldwide downy mildew epidemic, caused by the obligate oomycete Peronospora belbahrii...
April 23, 2018: BMC Plant Biology
https://www.readbyqxmd.com/read/29665816/selective-localization-of-igg-from-cerebrospinal-fluid-to-brain-parenchyma
#11
Marlene Thorsen Mørch, Sofie Forsberg Sørensen, Reza Khorooshi, Nasrin Asgari, Trevor Owens
BACKGROUND: Encounter of autoantibodies with specific antigens can lead to hypersensitivity reactions and pathology. In multiple sclerosis and neuromyelitis optica spectrum disease (NMOSD), immunoglobulin-G (IgG) deposition has been observed in pathological lesions in the central nervous system. The paradigmatic autoantibodies in NMOSD are specific for the water channel aquaporin-4, localized to astrocytic end-feet at the blood-brain barrier and ependymal cells at the cerebrospinal fluid-brain barrier...
April 17, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29629920/pleural-effusions-in-hematologic-malignancies-and-their-management-with-indwelling-pleural-catheters
#12
Erik Vakil, Carlos A Jimenez, Saadia A Faiz
PURPOSE OF REVIEW: Pleural effusions in patients with hematologic malignancy may represent malignant pleural effusion (MPE) or occur secondary to infection, treatment effects, and other common causes. The impact of MPE on prognosis in this cohort remains unclear. Indwelling pleural catheters (IPCs) are routinely placed for palliation of recurrent symptomatic MPEs, but perceived concerns over infection and bleeding may limit their use in patients with hematologic malignancies. However, recent evidence suggests IPCs are both well tolerated and effective in this cohort...
April 6, 2018: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/29628669/variation-in-the-practice-of-central-venous-catheter-and-chest-tube-insertions-among-surgery-residents
#13
Edward Eun Cho, Elizabeth Bevilacqua, Jeffrey Brewer, James Hassett, Weidun Alan Guo
Objectives: Central venous catheter (CVC) and chest tube (CT) insertions are common bedside procedures frequently performed by surgery residents. Despite published guidelines, variability in the practice exists. We sought to characterize the surgery residents' practice patterns surrounding these two bedside procedures. Materials and Methods: Over the last 1½ months of the academic year in 2012 and 2013, surgery residents across the US were surveyed online. Participants reported levels of agreement for 15 questions in a 5-point Likert scale format...
January 2018: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29611399/effect-of-central-line-bundle-compliance-on-central-line-associated-bloodstream-infections
#14
Kyoung Hwa Lee, Nan Hyoung Cho, Su Jin Jeong, Mi Na Kim, Sang Hoon Han, Young Goo Song
PURPOSE: The present study aimed to evaluate the effect of central line (CL) bundle compliance on central line-associated bloodstream infections (CLABSIs) in different departments of the same hospital, including the intensive care unit (ICU) and other departments. MATERIALS AND METHODS: The four components of the CL bundle were hand hygiene, use of maximal sterile barrier precautions, chlorhexidine use, and selection of an appropriate site for venous access. Compliance of the CL bundle and CLABSIs were measured for every department [emergency room (ER), ICU, general ward (GW), and operating room (OR)]...
May 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29604317/therapeutic-time-window-of-anti-high-mobility-group-box-1-antibody-administration-in-mouse-model-of-spinal-cord-injury
#15
Masahide Nakajo, Naohiro Uezono, Hideyuki Nakashima, Hidenori Wake, Setsuro Komiya, Masahiro Nishibori, Kinichi Nakashima
Spinal cord injury (SCI) is a devastating neurologic disorder that often leads to permanent disability, and there is no effective treatment for it. High mobility group box-1 (HMGB1) is a damage-associated molecular protein that triggers sterile inflammation upon injuries. We have previously shown that two administrations of neutralizing monoclonal antibody (mAb) against HMGB1 (immediately after (0 hours) and 6 hours after) SCI dramatically improves functional recovery after SCI in mice. However, when considering clinical application, 0 hours after SCI is not practical...
March 28, 2018: Neuroscience Research
https://www.readbyqxmd.com/read/29579817/sterility-and-safety-validation-for-transport-packaging-of-organs-and-tissues
#16
M Cobos, L Trunzo, M V Vogt, O Romero, C Anessi, J Pachado, M N Ciávaro, C Horak, M C Bacqué
The bags used in the transport of organs and tissues must be sterile, nontoxic, pyrogen free, and must serve as a barrier throughout their useful life. The goal of this study was to show the sterility, safety, and functionality of the bags subjected to irradiation, through validated procedures and techniques. The selected sterilization method was the use of gamma radiation. The sterilization dose was determined based on validated standards for the sterilization of medical products, ISO 11137-2: 2013 and ISO/TS 13004: 2013, using the Verification Dose Maximum method on samples belonging to 3 manufacturing lots...
March 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29574175/developing-process-maps-as-a-tool-for-a-surgical-infection-prevention-quality-improvement-initiative-in-resource-constrained-settings
#17
Jared A Forrester, Luca A Koritsanszky, Demisew Amenu, Alex B Haynes, William R Berry, Seifu Alemu, Fekadu Jiru, Thomas G Weiser
BACKGROUND: Surgical infections cause substantial morbidity and mortality in low-and middle-income countries (LMICs). To improve adherence to critical perioperative infection prevention standards, we developed Clean Cut, a checklist-based quality improvement program to improve compliance with best practices. We hypothesized that process mapping infection prevention activities can help clinicians identify strategies for improving surgical safety. STUDY DESIGN: We introduced Clean Cut at a tertiary hospital in Ethiopia...
March 21, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29564863/-nursing-care-experiences-of-periwound-moisture-associated-dermatitis-after-simultaneous-pancreas-kidney-transplantation
#18
Pei-Ying Yeh, Hsiao-Ping Chen, Jing-Yi Wu
Simultaneous pancreas-kidney (SPK) transplantation is the primary surgical treatment for type I diabetes mellitus with end-stage renal disease. However, this transplant surgery has a high-risk of surgical complications, including duodenal anastomotic leakage, which may lead to pancreas transplantation failure if the leakage worsens. This case report describes a patient who suffered from duodenal anastomotic leakage after SPK transplantation. The digestive enzymes eroded the wound and skin around the wound, resulting in periwound moisture-associated dermatitis...
April 2018: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29550386/maternal-exposure-to-silver-nanoparticles-are-associated-with-behavioral-abnormalities-in-adulthood-role-of-mitochondria-and-innate-immunity-in-developmental-toxicity
#19
Shayan Amiri, Aliakbar Yousefi-Ahmadipour, Mir-Jamal Hosseini, Arya Haj-Mirzaian, Majid Momeny, Heshmat Hosseini-Chegeni, Tahmineh Mokhtari, Sharmin Kharrazi, Gholamreza Hassanzadeh, Seyed Mohammad Amini, Somayeh Jafarinejad, Mahmoud Ghazi-Khansari
Silver nanoparticles (Ag-NPs) are currently used in a wide range of consumer products. Considering the small size of Ag-NPs, they are able to pass through variety of biological barriers and exert their effects. In this regard, the unique physicochemical properties of Ag-NPs along with its high application in the industry have raised concerns about their negative effects on human health. Therefore, it investigated whether prenatal exposure to low doses of Ag-NPs is able to induce any abnormality in the cognitive and behavioral performance of adult offspring...
March 14, 2018: Neurotoxicology
https://www.readbyqxmd.com/read/29547112/-anaerobic-bacteria-the-unknown-members-of-the-lung-microbiota
#20
Charles-Antoine Guilloux, Claudie Lamoureux, Geneviève Héry-Arnaud
Lungs were considered as sterile for a long time. However, it is now evident that the lungs of healthy people are colonized by microorganisms. Among the bacteria present in the pulmonary microbiota, a significant proportion is anaerobic (strict or facultative). Even though interest in the pulmonary microbiota is increasing, few studies have focused on these unknowns that represent the lung resident anaerobic bacteria. This review describes the biodiversity of anaerobes in physiological conditions, and in different chronic respiratory diseases (cystic fibrosis, COPD, asthma)...
March 2018: Médecine Sciences: M/S
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