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Obesity and hypertension in children

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https://www.readbyqxmd.com/read/27908845/design-response-rates-and-population-characteristics-of-a-cross-sectional-study-in-zanzibar-tanzania
#1
Maria Adam Nyangasa, Soerge Kelm, Mohammed Ali Sheikh, Antje Hebestreit
BACKGROUND: Data on nutritional status and correlates of noncommunicable diseases are scarce for resource-poor settings in sub-Saharan countries. With the scope of a project, "Access to Food and Nutrition Status of the Zanzibari Population," data for investigating public health questions were collected using proven measurement and laboratory standards. OBJECTIVE: The present study aims at providing a descriptive overview of recruitment approaches, standardization, quality control measures, and data collection, with special attention to the design, responses, and participant characteristics of the overall project...
December 1, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27903995/prevalence-of-hypertension-and-obesity-related-hypertension-in-urban-school-aged-children-in-rasht
#2
Hamidreza Badeli, Amir Hassankhani, Zahra Naeemi, Sahar Hosseinzadeh, Shima Mehrabi, Motahhareh Pourkarimi, Sajjad Hosseini, Pourya Rahbar Nikoukar, Reza Nezamdoust, Alireza Rahimi, Asemeh Pourrajabi
INTRODUCTION: Hypertension is a worldwide health concern. Complications of hypertension not only affect adult patients, but also involve children. Given the importance of assessing children with hypertension in order to decrease adulthood complications, we aimed to assess the prevalence of hypertension in urban school-aged children in Rasht, Iran. MATERIALS AND METHODS: This cross-sectional study was conducted on 2072 school-aged children in Rasht, Iran, from January 2013 to December 2015...
November 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27900314/renal-and-cardiovascular-morbidities-associated-with-apol1-status-among-african-american-and-non-african-american-children-with-focal-segmental-glomerulosclerosis
#3
Robert P Woroniecki, Derek K Ng, Sophie Limou, Cheryl A Winkler, Kimberly J Reidy, Mark Mitsnefes, Matthew G Sampson, Craig S Wong, Bradley A Warady, Susan L Furth, Jeffrey B Kopp, Frederick J Kaskel
BACKGROUND AND OBJECTIVES: African-American (AA) children with focal segmental glomerulosclerosis (FSGS) have later onset disease that progresses more rapidly than in non-AA children. It is unclear how APOL1 genotypes contribute to kidney disease risk, progression, and cardiovascular morbidity in children. DESIGN SETTING PARTICIPANTS AND MEASUREMENTS: We examined the prevalence of APOL1 genotypes and associated cardiovascular phenotypes among children with FSGS in the Chronic Kidney Disease in Children (CKiD) study; an ongoing multicenter prospective cohort study of children aged 1-16 years with mild to moderate kidney disease...
2016: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/27899001/drug-interventions-for-the-treatment-of-obesity-in-children-and-adolescents
#4
REVIEW
Emma Mead, Greg Atkinson, Bernd Richter, Maria-Inti Metzendorf, Louise Baur, Nicholas Finer, Eva Corpeleijn, Claire O'Malley, Louisa J Ells
BACKGROUND: Child and adolescent obesity has increased globally, and can be associated with significant short- and long-term health consequences. OBJECTIVES: To assess the efficacy of drug interventions for the treatment of obesity in children and adolescents. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, PubMed (subsets not available on Ovid), LILACS as well as the trial registers ICTRP (WHO) and ClinicalTrials.gov. Searches were undertaken from inception to March 2016...
November 29, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27887573/in-vitro-function-of-upstream-visfatin-polymorphisms-that-are-associated-with-adverse-cardiometabolic-parameters-in-obese-children
#5
Delicia Shu Qin Ooi, Siong Gim Ong, Chew Kiat Heng, Kah Yin Loke, Yung Seng Lee
BACKGROUND: Visfatin is an adipokine associated with glucose and lipid metabolism. We previously reported two visfatin upstream single nucleotide polymorphisms (SNPs), c.-3187G > A (rs11977021) and c.-1537C > T (rs61330082), which were in perfect linkage disequilibrium, in a Singaporean cohort of severely obese children and are associated with visfatin level and adverse cardiometabolic parameters. We aim to functionally characterize the effect of c.-3187G > A and c...
November 25, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27882931/plasma-sfrp5-and-adiponectin-levels-in-relation-to-blood-pressure-among-obese-children
#6
C Yin, H Chu, H Li, Y Xiao
The aim was to clarify the associations of five adipocytokines: Sfrp5, Wnt5a, adiponectin, chemerin and high-sensitivity C-reactive protein (hsCRP) with blood pressure (BP), and to examine whether BP can be influenced by changes in these adipocytokines in obese children after a 6-month lifestyle intervention. We conducted a cross-sectional study in 263 obese children and performed a 6-month lifestyle intervention in a subgroup of 89 obese children with hypertension. Anthropometric data, adiponectin, chemerin, Sfrp5 and Wnt5a were assessed at baseline and after 6-month lifestyle intervention...
November 24, 2016: Journal of Human Hypertension
https://www.readbyqxmd.com/read/27864799/primordial-prevention-of-cardiometabolic-risk-in-childhood
#7
Meryem A Tanrikulu, Mehmet Agirbasli, Gerald Berenson
Fetal life and childhood are important in the development of cardiometabolic risk and later clinical disease of atherosclerosis, hypertension and diabetes mellitus. Molecular and environmental conditions leading to cardiometabolic risk in early life bring us a challenge to develop effective prevention and intervention strategies to reduce cardiovascular (CV) risk in children and later disease. It is important that prevention strategies begin at an early age to reduce future CV morbidity and mortality. Pioneering work from longitudinal studies such as Bogalusa Heart Study (BHS), the Finnish Youth Study and other programs provide an awareness of the need for public and health services to begin primordial prevention...
November 19, 2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27864335/effects-of-maternal-obesity-on-placental-function-and-fetal-development
#8
Kristy R Howell, Theresa Powell
Obesity has reached epidemic proportions and pregnancies in obese mothers have increased risk for complications including gestational diabetes, hypertensive disorders, preterm birth and caesarian section. Children born to obese mothers are at increased risk of obesity and metabolic disease and are susceptible to develop neuropsychiatric and cognitive disorders. Changes in placental function not only play a critical role in the development of pregnancy complications but may also be involved in linking maternal obesity to long-term health risks in the infant...
November 18, 2016: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/27845280/-vaspin-levels-and-carbohydrate-status-in-young-patients-with-hypertension-and-obesity
#9
V Zlatkina
The current pace of growth in body weight and complications in children and patients of the young age is a serious problem. The aim of the work was to determine the vaspin concentration depending on the presence of obesity in patients of the young age with arterial hypertension and the study of its relationship with carbohydrate metabolism. The progression of obesity and hypertension is accompanied by increase of insulin resistance. The increase in the blood concentration of vaspin is observed in patients with hypertension and normal body weight...
October 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27814594/cardiac-allograft-vasculopathy-microvascular-arteriolar-capillaries-capioles-and-survival
#10
Carlos A Labarrere, Beate R Jaeger, Ghassan S Kassab
Cardiac allograft vasculopathy (CAV) is a serious complication of heart transplantation in adults and children. Risk factors include human leukocyte antigen mismatches, number and duration of rejection episodes, type of immunosuppression, antibody-mediated rejection, hypertension, hyperlipidemia, obesity, smoking, diabetes, cytomegalovirus infection, mode of donor brain death, donor age and ischemia/reperfusion injury. Endothelial injury and dysfunction in CAV are characterized by changes in adhesion molecules and up-regulation of major histocompatibility class II antigens followed by endothelial activation of complement C4d...
January 1, 2017: Frontiers in Bioscience (Elite Edition)
https://www.readbyqxmd.com/read/27812911/the-obesity-paradox-is-it-really-a-paradox-hypertension
#11
REVIEW
Alessandro Lechi
This article is a narrative overview of the role of hypertension on the relationships between obesity, morbidity, and mortality. We used as sources MEDLINE/PubMed, CINAHL, EMBASE, and Cochrane Library, from inception to March 2016. Key words include overweight, obesity, visceral obesity, obesity paradox, and hypertension. In addition, we hand-searched references from the retrieved articles. This work is one of the works of the topical collection "Obesity Paradox". The positive association between overweight, obesity, and cardiovascular diseases is well established, though this relation is typically U shaped with an increased risk in low-weight subjects or even a beneficial effect of overweight and obesity, the so-called "obesity paradox"...
November 4, 2016: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/27807091/cohort-profile-pacific-islands-families-pif-growth-study-auckland-new-zealand
#12
E Rush, M Oliver, L D Plank, S Taylor, L Iusitini, S Jalili-Moghaddam, F Savila, J Paterson, E Tautolo
PURPOSE: This article profiles a birth cohort of Pacific children participating in an observational prospective study and describes the study protocol used at ages 14-15 years to investigate how food and activity patterns, metabolic risk and family and built environment are related to rates of physical growth of Pacific children. PARTICIPANTS: From 2000 to 2015, the Pacific Islands Families Study has followed, from birth, the growth and development of over 1000 Pacific children born in Auckland, New Zealand...
November 2, 2016: BMJ Open
https://www.readbyqxmd.com/read/27792699/-prevalence-of-high-blood-pressure-and-their-association-with-body-mass-index-in-children-between-5-and-11-years-of-nahbalam-yucatan
#13
Leonel Alejandro Saury-Paredes
OBJECTIVE: To determine the prevalence of high blood pressure in children aged between 5-11 years in the community of Nahbalam, Yucatan, and its association with the body mass index. MATERIAL AND METHODS: A transversal study with children of the primary school "Lazaro Cardenas del Rio" was performed, measuring blood pressure, height, and weight of 259 girls and boys; systolic and/or diastolic blood pressure equal or greater than percentile 95 for gender, age, and height at three measures was considered as hypertension; prehypertension was considered as blood pressure equal or greater than percentile 90 but lower than percentile 95...
September 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27762638/body-habitus-in-heart-failure-understanding-the-mechanisms-and-clinical-significance-of-the-obesity-paradox
#14
Parham Parto, Carl J Lavie, Ross Arena, Samantha Bond, Dejana Popovic, Hector O Ventura
The prevalence of obesity among adults and children worldwide has reached epic proportions and has become a major independent risk factor for the development of heart failure (HF), in addition to a contributor of hypertension and cardiovascular disease. The implications of obesity in the development of HF involve adverse effects on cardiac structure and function. Despite all of this, in the setting of chronic HF, excess body mass is associated with improved clinical outcomes, demonstrating the presence of an obesity paradox...
October 20, 2016: Future Cardiology
https://www.readbyqxmd.com/read/27754239/os-34-06-status-of-cardiovascular-health-in-chinese-children-and-adolescents
#15
Yinkun Yan, Hongbo Dong, Junting Liu, Xiaoyuan Zhao, Hong Cheng, Dongqing Hou, Guimin Huang, Jie Mi
OBJECTIVE: In 2010, the American Heart Association (AHA) defined a set of four health behaviors and four health factors to evaluate cardiovascular health (CVH) status for children and adolescents. We aimed to examine the age-, sex-, and region- specific prevalence of ideal CVH and each CVH component among Chinese children and adolescents based on a nationally representative survey. DESIGN AND METHOD: Data were obtained from the China Children Blood Pressure Survey conducted in 2013-2014, which comprised of 10818 children and adolescents aged 6-18 years old from eight urban cities...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754171/sy-13-4-current-trends-in-blood-pressure-and-other-cardiovascular-risk-factors-in-adolescents
#16
Young Hwan Song
Hypertension is a major health problem in most developed and developing countries. Worldwide, about one billion people were found to have hypertension, and 13% of all deaths were closely related to hypertension. Secular trends in the prevalence of adult hypertension vary by country; some western countries show a decreasing trend for hypertension, while data from some developing countries show increasing prevalence of hypertension. So, it is difficult to predict the future changes in the prevalence of adult hypertension in some countries...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754170/sy-13-3-distribution-of-24-h-ambulatory-blood-pressure-in-children
#17
Jun Oh
Hypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults and children. There is a paucity of data on the long-term sequelae of persistent hypertension in children, but it is already known that children with hypertension have evidence of end organ damage and are at risk of hypertension into adulthood. The prevalence of hypertension in children is rising, most likely due to a concurrent rise in obesity rates. In children with hypertension, non-pharmacological measures are often recommended as first-line therapy, but a significant proportion of children will eventually require pharmacological treatment to reduce blood pressure, especially those with evidence of end organ damage at presentation or during follow-up...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753957/os-09-01-prevalence-of-hypertension-after-three-separate-occasions-among-chinese-children-a-national-representative-cross-section-survey
#18
Hui Fan, Yingkun Yan, HongBo Dong, Jie Mi
OBJECTIVE: It was recommended that the diagnosis of hypertension among children should be established on at least three separate occasions. However, the national prevalence of hypertension after three separate occasions was scant in China. The goal of our study was to determine the prevalence of hypertension on up to three separate visits in a Chinese pediatric population, and examined the association between hypertension and weight status. DESIGN AND METHOD: Data were obtained from a national representative sample of 43304 children aged 6-17 years...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753812/ssa-04-3-leptin-adiponectin-in-cardiometabolic-disease
#19
Patricio Lopez-Jaramillo
Cardiovascular diseases (CVD) are major causes of death and illness worldwide. In recent decades an increased prevalence of CVD mortality has been reported in low-medium income countries, which has been associated with changes in life styles, deficiencies in health systems and the persistence of social inequities.The metabolic syndrome comprises a cluster of cardiometabolic risk factors, with insulin resistance and increased adiposity as its central features. Identifying individuals with metabolic syndrome is important due to its association with an increased risk of coronary heart disease and type 2 diabetes mellitus (DM2)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27752263/the-prevalence-of-metabolic-syndrome-and-cardiovascular-risk-factors-in-obese-children-and-adolescents-in-dalmatia-a-hospital-based-study
#20
Marko Šimunović, Joško Božić, Lukrecija Milić, Ivana Unić, Veselin Škrabić
Obesity and metabolic syndrome (MS) are one of the biggest public health issues in child and adolescent population. To the best of the authors' knowledge, this hospital based study is the first report on the prevalence of MS in obese children and adolescents in Dalmatia, the Mediterranean part of Croatia. The objectives of this study were to determine the prevalence of individual cardiovascular risk factors and MS. Between January 2009 and June 2014, 201 obese subjects aged 6 to 18 were analyzed retrospectively from our Pediatric Endocrine Unit database...
2016: International Journal of Endocrinology
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