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Ellen Frank, Janice Pong, Yashvi Asher, Claudio N Soares
PURPOSE OF REVIEW: Depression is a complex and burdensome condition; it often leads to personal, societal and economic costs. Despite advances in treatments, its management over time remains a challenge; many treated for depression do not achieve full recovery or remain well for long. Novel ways to monitor patients are warranted, as well as better understanding of contributors to relapse or sustained wellness. Mobile health technologies (m-Health) are emerging as useful tools for real-time assessments of moods, behaviours and activities in a more convenient and less burdensome manner...
January 2018: Current Opinion in Psychiatry
Yashvi Wimalasena, Laura Kocierz, Dan Strong, Joanna Watterson, Brian Burns
Patients with respiratory distress present a frequent and challenging dilemma for emergency physicians (EPs). The accurate diagnosis and treatment of the underlying pathology is vitally important in these sick patients to ensure the best outcome and minimise harm from unnecessary treatments. Within the last decade, studies have shown lung ultrasonography (LU) to be valuable in the accurate diagnosis of a variety of lung pathologies, including cardiogenic pulmonary oedema, pleural effusion, pneumothorax, haemothorax and pneumonia...
March 3, 2017: Emergency Medicine Journal: EMJ
Yashvi Wimalasena, Brian Burns, Cliff Reid, Sandra Ware, Karel Habig
STUDY OBJECTIVE: The Greater Sydney Area Helicopter Emergency Medical Service undertakes in excess of 2,500 physician/paramedic out-of-hospital and interhospital retrievals each year, of which 8% require intubation. Emergency anesthesia of critically ill patients is associated with complications, including hypoxia. In July 2011, the service introduced apneic oxygenation with nasal cannulae to its emergency anesthesia standard operating procedure to reduce rates of desaturation during rapid sequence intubation...
April 2015: Annals of Emergency Medicine
Mark E Edsell, Yashvi H Wimalasena, William L Malein, Kimberly M Ashdown, Carla A Gallagher, Chris H Imray, Alex D Wright, Stephen D Myers
OBJECTIVE: Ascent to high altitude leads to a reduction in ambient pressure and a subsequent fall in available oxygen. The resulting hypoxia can lead to elevated pulmonary artery (PA) pressure, capillary stress, and an increase in interstitial fluid. This fluid can be assessed on lung ultrasound (LUS) by the presence of B-lines. We undertook a chamber and field study to assess the impact of high-intensity exercise in hypoxia on the development of pulmonary interstitial edema in healthy lowlanders...
December 2014: Wilderness & Environmental Medicine
Yashvi H Wimalasena, Alasdair R Corfield, Stephen Hearns
OBJECTIVE: To investigate the incidence and factors associated with desaturation related to emergency intubations within an aeromedical retrieval service pertaining to both primary prehospital and secondary interhospital missions. METHODS: A retrospective analysis of all rapid sequence intubations (RSI) was performed by the Emergency Medical Retrieval Service over a 4.5-year period (June 2008-November 2012). For each RSI, clinical indication for RSI, age, sex, traumatic or medical diagnosis, team leader specialty, Cormack and Lehane (C-L) grade of laryngoscope view, attempts at intubation, desaturation and hypotension was analysed...
August 2015: Emergency Medicine Journal: EMJ
Arthur R Bradwell, Stephen D Myers, Maggie Beazley, Kimberly Ashdown, Nick G Harris, Susie B Bradwell, Jamie Goodhart, Chris H Imray, Yashvi Wimalasena, Mark E Edsell, Kyle T S Pattinson, Alex D Wright, Stephen J Harris
OBJECTIVE: To assess the effect of acetazolamide (Az) on exercise performance during early acclimatization to altitude. METHODS: Az (250 mg twice daily) or placebo was administered for 3 days in a double-blind, randomized manner followed by a rapid ascent to 3459 m in the Italian Alps. Twenty healthy adults (age range, 18-67 years) were tested at 60% of sea-level peak power output for 15 minutes on a bicycle ergometer after 16 to 27 hours of altitude exposure. Exercise performance was measured in relation to peripheral oxygen saturations measured from pulse oximetry (Spo2), Lake Louise acute mountain sickness (AMS) score, and perceived difficulty...
September 2014: Wilderness & Environmental Medicine
Min Tae M Park, Jon Pipitone, Lawrence H Baer, Julie L Winterburn, Yashvi Shah, Sofia Chavez, Mark M Schira, Nancy J Lobaugh, Jason P Lerch, Aristotle N Voineskos, M Mallar Chakravarty
The cerebellum has classically been linked to motor learning and coordination. However, there is renewed interest in the role of the cerebellum in non-motor functions such as cognition and in the context of different neuropsychiatric disorders. The contribution of neuroimaging studies to advancing understanding of cerebellar structure and function has been limited, partly due to the cerebellum being understudied as a result of contrast and resolution limitations of standard structural magnetic resonance images (MRI)...
July 15, 2014: NeuroImage
Yashvi Wimalasena, Jeremy Windsor, Mark Edsell
High altitude pulmonary edema is a life-threatening condition that remains a concern for climbers and clinicians alike. Within the last decade, studies have shown ultrasonography to be valuable in the accurate diagnosis of a variety of lung pathologies, including cardiogenic pulmonary edema, pleural effusion, pneumothorax, and lung consolidation. Recently, studies conducted in remote areas have demonstrated that ultrasound lung comets can be used as a measure of subacute pulmonary edema and high altitude pulmonary edema in climbers ascending to altitude...
June 2013: Wilderness & Environmental Medicine
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