keyword
https://read.qxmd.com/read/38463868/birth-weight-discordance-and-adverse-neonatal-outcomes-in-appropriately-grown-premature-twins
#21
JOURNAL ARTICLE
Ling Yang, Yan Zhou, Jie Qiu, Nacheng Lin, Ning Gu, Yimin Dai
OBJECTIVE: This study aimed to analyze the clinical characteristics of birth weight discordant twins (BWDT) who were premature and appropriate-for-gestational-age or large-for-gestational-age. Additionally, it assessed the impact of birth weight discordance on the prognosis of appropriately grown premature twins, and investigated the effect of maternal factors on neonatal outcomes. STUDY DESIGN: This retrospective cohort study included twins who were born alive after preterm labor at the Nanjing Drum Tower Hospital from January 2018 to December 2021, along with their mothers...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38459440/the-role-of-nutrition-in-analysis-of-risk-factors-and-short-term-outcomes-for-late-onset-necrotizing-enterocolitis-among-very-preterm-infants-%C3%A2-a-nationwide-multicenter-study-in-china
#22
MULTICENTER STUDY
Kun-Yao Hong, Yao Zhu, Fan Wu, Jian Mao, Ling Liu, Rong Zhang, Yan-Mei Chang, Wei Shen, Li-Xia Tang, Xiu-Zhen Ye, Yin-Ping Qiu, Li Ma, Rui Cheng, Hui Wu, Dong-Mei Chen, Ling Chen, Ping Xu, Hua Mei, San-Nan Wang, Fa-Lin Xu, Rong Ju, Zhi Zheng, Xiao-Mei Tong, Xin-Zhu Lin
BACKGROUND: Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease, primarily affects preterm newborns and occurs after 7 days of life (late-onset NEC, LO-NEC). Unfortunately, over the past several decades, not much progress has been made in its treatment or prevention. This study aimed to analyze the risk factors for LO-NEC, and the impact of LO-NEC on short-term outcomes in very preterm infants (VPIs) with a focus on nutrition and different onset times. METHOD: Clinical data of VPIs were retrospectively collected from 28 hospitals in seven different regions of China from September 2019 to December 2020...
March 8, 2024: BMC Pediatrics
https://read.qxmd.com/read/38442693/the-incidence-of-necrotizing-enterocolitis-and-late-onset-sepsis-during-the-covid-19-pandemic-in-sweden-a-population-based-cohort-study
#23
JOURNAL ARTICLE
Elena Palleri, Anna Svenningsson, Laszlo Markasz, Helene Engstrand Lilja
INTRODUCTION: The effect of the pandemic restrictions in the NICUs is not well studied. Necrotizing enterocolitis (NEC) is characterized by intestinal inflammation and bacterial invasion. This study aimed to investigate whether the incidence of NEC has changed during the COVID-19 pandemic in Sweden and whether it was associated with a change in the frequency of extremely preterm births. METHODS: Data were retrieved from the Swedish Neonatal Quality Register (SNQ) for infants registered between January 2017 and December 2021 born below a gestational age of 35 weeks...
March 5, 2024: Neonatology
https://read.qxmd.com/read/38439024/physiological-based-cord-clamping-in-very-preterm-infants-the-aeration-breathing-clamping-3-abc3-trial-statistical-analysis-plan-for-a-multicenter-randomized-controlled-trial
#24
RANDOMIZED CONTROLLED TRIAL
Sten P Willemsen, Ronny Knol, Emma Brouwer, Thomas van den Akker, Philip L J DeKoninck, Enrico Lopriore, Wes Onland, Willem P de Boode, Anton H van Kaam, Debbie H Nuytemans, Irwin K M Reiss, G Jeroen Hutten, Sandra A Prins, Estelle E M Mulder, Christian V Hulzebos, Sam J van Sambeeck, Mayke E van der Putten, Inge A Zonnenberg, Arjan B Te Pas, Marijn J Vermeulen
BACKGROUND: Mortality, cerebral injury, and necrotizing enterocolitis (NEC) are common complications of very preterm birth. An important risk factor for these complications is hemodynamic instability. Pre-clinical studies suggest that the timing of umbilical cord clamping affects hemodynamic stability during transition. Standard care is time-based cord clamping (TBCC), with clamping irrespective of lung aeration. It is unknown whether delaying cord clamping until lung aeration and ventilation have been established (physiological-based cord clamping, PBCC) is more beneficial...
March 4, 2024: Trials
https://read.qxmd.com/read/38438550/perinatal-risk-factors-associated-with-acute-kidney-injury-severity-and-duration-among-infants-born-extremely-preterm
#25
JOURNAL ARTICLE
Keia Sanderson, Russell Griffin, Nekayla Anderson, Andrew M South, Jonathan R Swanson, Michael Zappitelli, Heidi J Steflik, Marissa J DeFreitas, Jennifer Charlton, David Askenazi
BACKGROUND: We evaluated time-varying perinatal risk factors associated with early (≤7 post-natal days) and late (>7 post-natal days) severe acute kidney injury (AKI) occurrence and duration. METHODS: A secondary analysis of Preterm Erythropoietin Neuroprotection Trial data. We defined severe AKI (stage 2 or 3) per neonatal modified Kidney Disease: Improving Global Outcomes criteria. Adjusted Cox proportional hazards models were conducted with exposures occurring at least 72 h before severe AKI...
March 4, 2024: Pediatric Research
https://read.qxmd.com/read/38436311/-predictive-value-of-hemoglobin-decrease-for-necrotizing-enterocolitis-in-preterm-infants-with-late-onset-sepsis
#26
JOURNAL ARTICLE
Na Cai, Lei-Lei Shen, Sheng Chen
OBJECTIVES: To study the predictive value of hemoglobin (Hb) decrease for the occurrence of necrotizing enterocolitis (NEC) in preterm infants with late-onset sepsis (LOS) . METHODS: Clinical data of 93 LOS preterm infants were collected for retrospective analysis, among which 16 infants developed NEC while 77 infants did not. Based on the decrease in Hb levels from the most recent Hb measurement before LOS occurrence to the initial Hb levels during LOS, the infants were divided into three groups: no Hb decrease ( n =15), mild Hb decrease (Hb decrease <15 g/L; n =35), and severe Hb decrease (Hb decrease ≥15 g/L; n =43)...
February 15, 2024: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://read.qxmd.com/read/38434229/short-term-outcomes-of-early-oral-colostrum-administration-in-vlbw-neonates-an-open-label-randomized-controlled-trial
#27
JOURNAL ARTICLE
Sedigheh Tehranchi, Farzaneh Palizban, Maryam Khoshnood Shariati, Naeeme Taslimi Taleghani, Arefeh Fayazi, Mohammad Farjami
BACKGROUND: Oropharyngeal colostrum priming (OCP) has been proposed as a potential nutritional option for very low birth weight (VLBW) newborns. This study aimed to determine short-term outcomes of early oral colostrum administration in VLBW neonates. METHODS: This open-label randomized controlled trial was conducted on VLBW neonates admitted to Mahdieh Hospital, Tehran, Iran, between February and December 2022. According to the protocol, all eligible neonates were randomized evenly to the intervention group, which received oral colostrum (OC), and the control group, which received no OC...
2024: Medical Journal of the Islamic Republic of Iran
https://read.qxmd.com/read/38432888/clinical-characteristics-of-bronchopulmonary-dysplasia-in-very-preterm-infants
#28
JOURNAL ARTICLE
Yonghui Yang, Xiaori He, Xuefei Zhang, Pingyang Chen
OBJECTIVES: With the development of perinatal and neonatal intensive care medicine, the survival rate of very premature infants increases year by year. However, the incidence of bronchopulmonary dysplasia (BPD) increases year by year, which seriously affects the survival prognosis of very premature infants. How to prevent and treat BPD effectively has become the focus of neonatologists. This study aims to provide ideas for the prevention and treatment of BPD in very preterm infants via analyzing the clinical characteristics of BPD...
October 28, 2023: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://read.qxmd.com/read/38432084/a-multi-institutional-study-comparing-stoma-location-in-neonates-with-intestinal-perforation
#29
JOURNAL ARTICLE
Stephanie Y Chen, Gabriella Grisotti, Shale J Mack, Ashley E Walther, Rachel L Chapman, Richard A Falcone, Eugene S Kim
INTRODUCTION: Neonates with intestinal perforation often require laparotomy and intestinal stoma creation, with the stoma placed in either the laparotomy incision or a separate site. We aimed to investigate if stoma location is associated with risk of postoperative wound complications. METHODS: A multi-institutional retrospective review was performed for neonates ≤3 mo who underwent emergent laparotomy and intestinal stoma creation for intestinal perforation between January 1, 2009 and April 1, 2021...
March 2, 2024: Journal of Surgical Research
https://read.qxmd.com/read/38431920/mir-375-3p-targets-ywhab-to-attenuate-intestine-injury-in-neonatal-necrotizing-enterocolitis
#30
JOURNAL ARTICLE
Li Nan, Fan Kaisi, Zhang Mengzhen, Yang Yang, Yang Jiaming, Yang Huirong, Hou Xinwei, Wang Chen, Yang Liucheng, Wu Kai
PURPOSE: Necrotizing enterocolitis (NEC) is a significant contributor to neonatal mortality. This study aimed to investigate the role of high levels of miR-375-3p in breast milk in the development of NEC and elucidate its mechanism. METHODS: Differential expression of miR-375-3p in the intestines of breast-fed and formula-fed mice was confirmed using real-time polymerase chain reaction (RT-PCR). NEC mice models were established, and intestinal injury was assessed using HE staining...
March 3, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38429791/impact-of-hyperoxia-on-the-gut-during-critical-illnesses
#31
REVIEW
Ninan Dai, Juan Gu, Yanhong Luo, Yuanfa Tao, Yuehting Chou, Ying He, Han Qin, Tao Chen, Xiaoyun Fu, Miao Chen, Zhouxiong Xing
Molecular oxygen is typically delivered to patients via oxygen inhalation or extracorporeal membrane oxygenation (ECMO), potentially resulting in systemic hyperoxia from liberal oxygen inhalation or localized hyperoxia in the lower body from peripheral venoarterial (VA) ECMO. Consequently, this exposes the gastrointestinal tract to excessive oxygen levels. Hyperoxia can trigger organ damage due to the overproduction of reactive oxygen species and is associated with increased mortality. The gut and gut microbiome play pivotal roles in critical illnesses and even small variations in oxygen levels can have a dramatic influence on the physiology and ecology of gut microbes...
March 1, 2024: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38422245/analysis-of-bifidobacterium-animalis-subsp-lactis-bb-12-%C3%A2-and-lactobacillus-rhamnosus-gg-on-underweight-and-malabsorption-in-premature-infants
#32
JOURNAL ARTICLE
Meng Xing, Xuran Li, Yinzhu Zhang
OBJECTIVE: This study aimed to explore and analyze the therapeutic effect of the combination of Bifidobacterium animalis subsp. lactis BB-12® and Lactobacillus rhamnosus GG on underweight and malabsorption in premature infants. METHODS: This is a retrospective study. The clinical data of 68 premature infants admitted to Beijing United Family Hospital (Private Secondary Comprehensive Hospital, Chaoyang District, Beijing, China) from January 2016 to January 2022 were analyzed retrospectively...
2024: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/38418993/factors-influencing-necrotizing-enterocolitis-in-premature-infants-in-china-a-systematic-review-and-meta-analysis
#33
JOURNAL ARTICLE
Shuliang Zhao, Huimin Jiang, Yiqun Miao, Wenwen Liu, Yanan Li, Hui Liu, Aihua Wang, Xinghui Cui, Yuanyuan Zhang
BACKGROUND: Necrotizing enterocolitis (NEC) is a multifactorial gastrointestinal disease with high morbidity and mortality among premature infants. However, studies with large samples on the factors of NEC in China have not been reported. This meta-analysis aims to systematically review the literature to explore the influencing factors of necrotizing enterocolitis in premature infants in China and provide a reference for the prevention of NEC. METHODS: PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), China Biomedical Literature Database (CBM), Wanfang and VIP databases were systematically searched from inception to February 2023...
February 29, 2024: BMC Pediatrics
https://read.qxmd.com/read/38418592/recombinant-igf-1-bp3-protects-against-intestinal-injury-in-a-neonatal-mouse-nec-model
#34
JOURNAL ARTICLE
Xiaocai Yan, Elizabeth Managlia, Galen Carey, Norman Barton, Xiao-Di Tan, Isabelle G De Plaen
BACKGROUND: Recombinant human IGF-1/binding protein-3 (rhIGF-1/BP3) is currently being tested in phase II clinical trials in premature infants to prevent bronchopulmonary dysplasia, but its impact on the neonatal intestine remains unclear. The aim of this study was to determine whether rhIGF-1/BP3 protects against necrotizing enterocolitis (NEC) in mice and to investigate the mechanisms involved. METHODS: Neonatal mice were dam fed or injected intraperitoneally with rhIGF-1/BP3 (or vehicle) and submitted to an experimental NEC model...
February 28, 2024: Pediatric Research
https://read.qxmd.com/read/38417782/management-of-hematochezia-in-infants-with-congenital-heart-disease-admitted-to-the-acute-care-cardiology-unit-a-multi-center-retrospective-pilot-study
#35
JOURNAL ARTICLE
Sarah Pradhan, Courtney Strohacker, Susan Schachtner, Kelsey Palm, Amiee Trauth, Zhiqian Gao, Elisa Marcuccio
OBJECTIVE: To assess the evaluation and prevalence of benign hematochezia (BH) versus necrotizing enterocolitis (NEC) in infants with congenital heart disease (CHD) <6 months old admitted to the Acute Care Cardiology Unit (ACCU). STUDY DESIGN: A multicenter retrospective review of patient characteristics and evaluation of all hematochezia events in patients with CHD <6 months admitted to ACCU at three high-volume tertiary care centers from February 2019 to January 2021...
February 26, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38416365/does-early-fortification-of-human-milk-decrease-time-to-regain-birth-weight-as-compared-to-late-fortification-among-preterm-infants-a-randomized-controlled-trial
#36
JOURNAL ARTICLE
Gaurav Gupta, A Murugesan, S Thanigainathan, B Adhisivam
OBJECTIVES: To compare the duration required to regain birth weight following early fortification of human milk vs. late fortification among preterm infants. METHODS: This randomized controlled trial included hemodynamically stable 120 preterm infants (≤32 wk of gestation). The intervention and comparator groups received standard fortification with human milk fortifier when enteral feeds reached 30 ml/kg/d (early fortification) and 80 ml/kg/d (late fortification) respectively...
February 28, 2024: Indian Journal of Pediatrics
https://read.qxmd.com/read/38413889/risk-factor-analysis-and-nomogram-prediction-model-construction-for-nec-complicated-by-intestinal-perforation
#37
JOURNAL ARTICLE
Pei Huang, Nandu Luo, Xiaoqi Shi, Jiahong Yan, Jiaojiao Huang, Yan Chen, Zuochen Du
OBJECTIVE: To investigate the clinical characteristics of neonatal necrotizing enterocolitis (NEC) complicated by intestinal perforation and predict the incidence of intestinal perforation in NEC. METHODS: Neonates diagnosed with NEC at the Affiliated Hospital of Zunyi Medical University from January 2012 to May 2022 were enrolled, and the clinical data were collected and analyzed retrospectively. The patients were divided into two groups based on intestinal perforation occurrence or not...
February 27, 2024: BMC Pediatrics
https://read.qxmd.com/read/38413766/reassessing-acquired-neonatal-intestinal-diseases-using-unsupervised-machine-learning
#38
JOURNAL ARTICLE
Daniel R Gipson, Alan L Chang, Allison C Lure, Sonia A Mehta, Taylor Gowen, Erin Shumans, David Stevenson, Diomel de la Cruz, Nima Aghaeepour, Josef Neu
BACKGROUND: Acquired neonatal intestinal diseases have an array of overlapping presentations and are often labeled under the dichotomous classification of necrotizing enterocolitis (which is poorly defined) or spontaneous intestinal perforation, hindering more precise diagnosis and research. The objective of this study was to take a fresh look at neonatal intestinal disease classification using unsupervised machine learning. METHODS: Patients admitted to the University of Florida Shands Neonatal Intensive Care Unit January 2013-September 2019 diagnosed with an intestinal injury, or had imaging findings of portal venous gas, pneumatosis, abdominal free air, or had an abdominal drain placed or exploratory laparotomy during admission were included...
February 27, 2024: Pediatric Research
https://read.qxmd.com/read/38413758/the-impact-of-volume-and-neonatal-level-of-care-on-outcomes-of-moderate-and-late-preterm-infants
#39
JOURNAL ARTICLE
Elizabeth G Salazar, Molly Passarella, Brielle Formanowski, Ciaran S Phibbs, Scott A Lorch, Sara C Handley
OBJECTIVE: Evaluate the relationship of neonatal unit level of care (LOC) and volume with mortality or morbidity in moderate-late preterm (MLP) (32-36 weeks' gestation) infants. DESIGN: Retrospective cohort study of 650,865 inborn MLP infants in 4976 hospitals-years using 2003-2015 linked administrative data from 4 states. Exposure was combined neonatal LOC and MLP annual volume. The primary outcome was death or morbidity (respiratory distress syndrome, severe intraventricular hemorrhage, necrotizing enterocolitis, sepsis, infection, pneumothorax, extreme length of stay) with components as secondary outcomes...
February 27, 2024: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/38413262/association-of-exclusive-breast-milk-intake-and-outcomes-in-infants-with-uncomplicated-gastroschisis-a-national-cohort-study
#40
JOURNAL ARTICLE
Emily Hodgson, Daniel Briatico, Sarah Klapman, Erik Skarsgard, Marc Beltempo, Prakesh S Shah, Esther Huisman, J Mark Walton, Michael H Livingston
BACKGROUND: Enteral feeding is an essential part of the management of infants with gastroschisis. We hypothesized that exclusive breast milk is associated with improved neonatal outcomes. METHODS: We conducted a retrospective review of infants with uncomplicated gastroschisis through the Canadian Pediatric Surgery Network (CAPSNet) and Canadian Neonatal Network (CNN). The primary outcome was time to full enteral feeds. RESULTS: We identified 411 infants with gastroschisis treated at CAPSNet centres from 2014 to 2022...
February 3, 2024: Journal of Pediatric Surgery
keyword
keyword
850
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.