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https://www.readbyqxmd.com/read/27908556/the-relationship-between-neutrophil-to-lymphocyte-ratio-and-intracerebral-hemorrhage-in-type-2-diabetes-mellitus
#1
Peng Luo, Rui Li, Siyuan Yu, Tingting Xu, Shufan Yue, Yongli Ji, Xin Chen, Haiting Xie
INTRODUCTION: Chronic systematic inflammation has been suggested to be associated with the occurrence and development of cardiovascular events. Low-grade systematic inflammation persists in type 2 diabetes mellitus (T2DM) patients. In addition, the risk of cerebral hemorrhage in these patients is increased compared with non-diabetic patients. Neutrophil-to-lymphocyte ratio (NLR) is the ratio derived by dividing the neutrophil count with the lymphocyte count from a peripheral blood sample...
November 28, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27852246/comparison-of-intraocular-pressure-andvault-after-implantation-of-implantable-collamer-lens-with-and-without-a-central-hole
#2
Haiting Chen, Guangzeng Niu, Yuxiang Fan, Jingxue Ma
BACKGROUD: The Implantable Collamer Lens (ICL) has been used widely for refractive errors, We performed this prospective randomized comparative study to compare postoperative intraocular pressure (IOP) and vaults of the eyes implanted with conventional ICL and central hole ICL. METHODS: This study evaluated 44 eyes of 22 patients who underwent central hole ICL implantation in one eye and conventional ICL implantation in the other eye by randomization assignment...
November 16, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27843199/corrigendum-to-sphingosine-1-phosphate-signaling-in-immune-cells-and-inflammation-roles-and-therapeutic-potential
#3
Masayo Aoki, Hiroaki Aoki, Rajesh Ramanathan, Nitai C Hait, Kazuaki Takabe
[This corrects the article DOI: 10.1155/2016/8606878.].
2016: Mediators of Inflammation
https://www.readbyqxmd.com/read/27775533/hemespred-structure-based-ligand-specific-heme-binding-residues-prediction-by-using-fast-adaptive-ensemble-learning-scheme
#4
Jian Zhang, Haiting Chai, Bo Gao, Guifu Yang, Zhiqiang Ma
Heme is an essential biomolecule that widely exists in numerous extant organisms. Accurately identifying heme binding residues (HEMEs) is of great importance in disease progression and drug development. In this study, a novel predictor named HEMEsPred was proposed for predicting HEMEs. First, several sequence- and structure-based features, including amino acid composition, motifs, surface preferences and secondary structure, were collected to construct feature matrices. Second, a novel fast-adaptive ensemble learning scheme was designed to overcome the serious class-imbalance problem as well as to enhance the prediction performance...
October 4, 2016: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/27770884/bis-naphthalimides-self-assembly-organogel-formation-and-application-in-detection-of-p-phenylenediamine
#5
Xinhua Cao, Na Zhao, Aiping Gao, Haiting Lv, Yuling Jia, Renmiao Wu, Yongquan Wu
Two new gelators containing bis-naphthalimides group were designed and synthesized. The gelator 1b could form gels in DMF and mixed solvent of DMSO/H2O (10/1, v/v). The self-assembly processes of 1b in two kinds of solvents were detailedly investigated by UV-vis, fluorescence, infrared spectroscopy, field emission scanning electron microscope (FE-SEM), X-ray diffraction and contact angle experiments. The experiment results showed the hydrogen bonding was the main force for the gel formation. The gel 1b formed in mixed solvent of DMSO/H2O (10/1, v/v) possessed of the ability of distinguishing of o-phenylenediamine, m-phenylenediamine and p-phenylenediamine...
January 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27765801/targeting-pp2a-to-overcome-enzalutamide-resistance-in-ar-breast-tumors
#6
LETTER
Ion Cristóbal, Blanca Torrejón, Manuel Pedregal, Federico Rojo, Jesús García-Foncillas
No abstract text is available yet for this article.
January 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/27693036/the-lncrna-h19-interacts-with-mir-140-to-modulate-glioma-growth-by-targeting-iaspp
#7
Haiting Zhao, Renjun Peng, Qing Liu, Dingyang Liu, Peng Du, Jian Yuan, Gang Peng, Yiwei Liao
H19, one of the first found cancer-associated long non-coding RNAs (lncRNAs), is involved in the development and progression of many types of tumors. An aberrant expression of H19 was observed in hepatocellular carcinoma, cervical cancer, breast cancer, ovarian cancer, and colorectal cancer. However, the exact effects and molecular mechanisms of H19 in glioma progression are still unknown up to now. In this study, we investigated the role of H19 in human glioma cell lines and clinical tumor samples in order to determine the function of this molecule...
September 28, 2016: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/27685199/steric-structure-dependent-gel-formation-hierarchical-structures-rheological-behavior-and-surface-wettability
#8
Xinhua Cao, Na Zhao, Ruohan Li, Haiting Lv, Zongwen Zhang, Aiping Gao, Tao Yi
A series of bicholesteryl-based gelators with different central linker atoms C, N, and O (abbreviated to GC, GN, and GO, respectively) have been designed and synthesized. The self-assembly processes of these gelators were investigated by using gelation tests, field-emission scanning electron microscopy, field-emission transmission electron microscopy, UV/Vis absorption, IR spectroscopy, X-ray diffraction, rheology, and contact-angle experiments. The gelation ability, self-assembly morphology, rheological, and surface-wettability properties of these gelators strongly depend on the central linker atom of the gelator molecule...
September 29, 2016: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/27681506/increased-interleukin-35-expression-in-tumor-infiltrating-lymphocytes-correlates-with-poor-prognosis-in-patients-with-breast-cancer
#9
Zhonghua Zhao, Xi Chen, Shengnan Hao, Rui Jia, Nana Wang, Shaoshui Chen, Mianli Li, Chuanxin Wang, Haiting Mao
Interleukin-35 (IL-35) is a recently discovered inhibitory cytokine, which is firstly discovered to be produced by regulatory T cells (Tregs) and proposed as a key effector molecule of Treg function. This study aims to analyze the correlation between IL-35 expression in tumor-infiltrating lymphocytes (TILs) of breast cancer tissue and patients' clinical characteristics. Plasma IL-35 was also determined in 60 patients with breast invasive ductal carcinoma (IDC) and 30 healthy women by enzyme-linked immunosorbent assay...
September 24, 2016: Cytokine
https://www.readbyqxmd.com/read/27663707/a-review-on-automated-sorting-of-source-separated-municipal-solid-waste-for-recycling
#10
Sathish Paulraj Gundupalli, Subrata Hait, Atul Thakur
A crucial prerequisite for recycling forming an integral part of municipal solid waste (MSW) management is sorting of useful materials from source-separated MSW. Researchers have been exploring automated sorting techniques to improve the overall efficiency of recycling process. This paper reviews recent advances in physical processes, sensors, and actuators used as well as control and autonomy related issues in the area of automated sorting and recycling of source-separated MSW. We believe that this paper will provide a comprehensive overview of the state of the art and will help future system designers in the area...
September 20, 2016: Waste Management
https://www.readbyqxmd.com/read/27623533/high-performance-pbse-colloidal-quantum-dot-vertical-field-effect-phototransistors
#11
Haiting Zhang, Yating Zhang, Xiaoxian Song, Yu Yu, Mingxuan Cao, Yongli Che, Jianlong Wang, Junbo Yang, Haitao Dai, Guizhong Zhang, Jianquan Yao
Here, vertical field effect phototransistors (VFEPTs) based on lead selenide colloidal quantum dots (PbSe CQDs) for infrared photo detection were investigated, using Au/Ag nanowires as the source transparent electrode. VFEPTs have the advantage of easy fabrication of ultrashort channel length devices, as the channel length is simply determined here by the PbSe CQDs active layer's thickness (260 nm). In ultrashort channels, photo-excited carriers quickly (in nanoseconds) transfer to the drain. As soon as a hole (electron) reaches the drain, a hole (electron) is replenished from the source...
October 21, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27578613/high-performance-ambipolar-self-assembled-au-ag-nanowire%C3%A2-based-vertical-quantum-dot-field-effect-transistor
#12
Xiaoxian Song, Yating Zhang, Haiting Zhang, Yu Yu, Mingxuan Cao, Yongli Che, Jianlong Wang, Haitao Dai, Junbo Yang, Xin Ding, Jianquan Yao
Most lateral PbSe quantum dot field effect transistors (QD FETs) show a low on current/off current (I on/I off) ratio in charge transport measurements. A new strategy to provide generally better performance is to design PbSe QD FETs with vertical architecture, in which the structure parameters can be tuned flexibly. Here, we fabricated a novel room-temperature operated vertical quantum dot field effect transistor with a channel of 580 nm, where self-assembled Au/Ag nanowires served as source transparent electrodes and PbSe quantum dots as active channels...
October 7, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27575365/a-crossover-crossback-prospective-study-of-dibutyl-phthalate-exposure-from-mesalamine-medications-and-semen-quality-in-men-with-inflammatory-bowel-disease
#13
Feiby L Nassan, Brent A Coull, Niels E Skakkebaek, Michelle A Williams, Ramace Dadd, Lidia Mínguez-Alarcón, Stephen A Krawetz, Elizabeth J Hait, Joshua R Korzenik, Alan C Moss, Jennifer B Ford, Russ Hauser
BACKGROUND: Phthalates are widely used chemicals with ubiquitous exposure. Dibutyl-phthalate (DBP), a male reproductive toxicant in animals, is understudied in humans. Some mesalamine medications used to treat inflammatory bowel disease (IBD) have DBP in their coating, whereas other mesalamine formulations do not. OBJECTIVES: Taking advantage of differences in mesalamine formulations, we investigated whether high-DBP exposure from mesalamine medications was associated with decreased semen parameters...
October 2016: Environment International
https://www.readbyqxmd.com/read/27565741/identification-of-dna-binding-proteins-using-multi-features-fusion-and-binary-firefly-optimization-algorithm
#14
Jian Zhang, Bo Gao, Haiting Chai, Zhiqiang Ma, Guifu Yang
BACKGROUND: DNA-binding proteins (DBPs) play fundamental roles in many biological processes. Therefore, the developing of effective computational tools for identifying DBPs is becoming highly desirable. RESULTS: In this study, we proposed an accurate method for the prediction of DBPs. Firstly, we focused on the challenge of improving DBP prediction accuracy with information solely from the sequence. Secondly, we used multiple informative features to encode the protein...
2016: BMC Bioinformatics
https://www.readbyqxmd.com/read/27548247/high-prevalence-of-eosinophilic-gastrointestinal-disease-in-children-with-intestinal-failure
#15
Danielle A Stamm, Elizabeth Hait, Heather J Litman, Paul D Mitchell, Christopher Duggan
OBJECTIVES: The aim of the present study was to describe the prevalence and clinical features of gastrointestinal (GI) eosinophilic inflammation among pediatric patients with intestinal failure (IF). METHODS: Medical records of all patients studied in our institution's IF program who underwent GI endoscopy over a 15-year period were reviewed, and clinical, pathologic, nutrition, and laboratory data collected. RESULTS: One hundred five patients underwent 208 GI endoscopic procedures with biopsy...
September 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27463926/platinum-scatterer-based-random-lasers-from-dye-doped-polymer-dispersed-liquid-crystals-in-capillary-tubes
#16
Jianlong Wang, Yating Zhang, Mingxuan Cao, Xiaoxian Song, Yongli Che, Haiting Zhang, Heng Zhang, Jianquan Yao
The resonance characteristics of platinum-scatter-based random lasers from dye-doped polymer-dispersed liquid crystals (DDPDLCs) in capillary tubes were researched for the first time, to the best of our knowledge. After adding platinum nanoparticles (Pt NPs) into the liquid crystal mixtures, the emission spectra of DDPDLCs revealed a lower lasing threshold in comparison with those of DDPDLCs without Pt NPs due to light scattering of liquid crystal droplets and the local field enhancement around Pt NPs. Furthermore, the full width at half-maximum (FWHM) and the lasing threshold were determined by the doping density of the Pt NPs...
July 20, 2016: Applied Optics
https://www.readbyqxmd.com/read/27459945/the-roles-of-bile-acids-and-sphingosine-1-phosphate-signaling-in-the-hepatobiliary-diseases
#17
REVIEW
Masayuki Nagahashi, Kizuki Yuza, Yuki Hirose, Masato Nakajima, Rajesh Ramanathan, Nitai C Hait, Phillip B Hylemon, Huiping Zhou, Kazuaki Takabe, Toshifumi Wakai
Based on research carried out over the last decade, it has become increasingly evident that bile acids act not only as detergents, but also as important signaling molecules that exert various biological effects via activation of specific nuclear receptors and cell signaling pathways. Bile acids also regulate the expression of numerous genes encoding enzymes and proteins involved in the synthesis and metabolism of bile acids, glucose, fatty acids, and lipoproteins, as well as energy metabolism. Receptors activated by bile acids include, farnesoid X receptor α, pregnane X receptor, vitamin D receptor, and G protein-coupled receptors, TGR5, muscarinic receptor 2, and sphingosine-1-phosphate receptor (S1PR)2...
September 2016: Journal of Lipid Research
https://www.readbyqxmd.com/read/27376869/source-insights-into-the-11-h-daytime-and-nighttime-fine-ambient-particulate-matter-in-china-as-well-as-the-synthetic-studies-using-the-new-multilinear-engine-2-species-ratios-me2-sr-method
#18
Guoliang Shi, Gang Chen, Guirong Liu, Haiting Wang, Yingze Tian, Yinchang Feng
Modeled results are very important for environmental management. Unreasonable modeled result can lead to wrong strategy for air pollution management. In this work, an improved physically constrained source apportionment (PCSA) technology known as Multilinear Engine 2-species ratios (ME2-SR) was developed to the 11-h daytime and nighttime fine ambient particulate matter in urban area. Firstly, synthetic studies were carried out to explore the effectiveness of ME2-SR. The estimated source contributions were compared with the true values...
October 1, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27373088/-long-term-outcome-of-budesonide-middle-meatus-treatment-for-chronic-rhinosinusitis-patients-following-endoscopic-sinus-surgery
#19
Xiaodong Chen, Haiting Wang, Zhaohui Shi, Xiaoyuan Li, Boyi Shan, Tao Xue, Li Qiao, Fuquan Chen
OBJECTIVE: To investigate the long term clinical effect of budesonide treatment in middle meatus for chronic rhinosinusitis(CRS) following endoscopic sinus surgery (ESS). METHOD: A total number of 53 patients with CRS received ESS were divided into two groups according to budesonide treatment: budesonide-treated group with 21 cases (39.6%) and control group with 32 cases (60.4%). Gelatin sponges soaked with 1 ml budesonide suspension were put in middle meatus in budesonide-treated group, while only gelatin sponges were put in middle meatus in control group...
February 2016: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/27364161/expression-purification-and-characterization-of-recombinant-canine-fgf21-in-escherichia-coli
#20
Zhong Zheng, Chengjun Yang, Ruofeng Yin, Jinxi Jiang, Haiting He, Xinxin Wang, Mujie Kan, Yechen Xiao
The canine metabolic diseases, such as obesity and diabetes, have become a worldwide problem. Fibroblast growth factor 21 (FGF21) is a potent regulator which has many biological functions relative to metabolism regulation. It suggests that FGF21 plays important roles in regulating canine metabolic diseases. To acquire the recombinant canine FGF21 (rcFGF21) in Escherichia coli, the recombinant bacteria were induced by 0.5 mM IPTG for 16 hours at 16 °C, and the rcFGF21 protein was purified by Ni-NTA. 8 mg rcFGF21 was acquired from one liter bacteria...
2016: Protein and Peptide Letters
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