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CD 73

Nurhan Sahin, Ayse Nur Akatli, Muhammet Reha Celik, Hakkı Ulutas, Emine Turkmen Samdanci, Cemil Colak
Pleural Malignant Mesothelioma (MM) is a fatal disease that has been associated with asbestos exposure. Differential diagnosis between the pleural infiltration of pulmonary carcinomas and MM is rather difficult particularly for epitheloid type mesothelioma.We aimed to investigate the utility of CD90, a cancer stem cell marker, in the differential diagnosis of MM and lung carcinoma, its prognostic significance and compare its value with that of Calretinin. Ninety pathology specimens including MM (n:30), pulmonary adenocarcinoma (n:30) and pulmonary squamous cell carcinoma (n:30) were used in this study...
October 19, 2016: Pathology Oncology Research: POR
Ahmed Sarkhy, Mohammad I El Mouzan, Elshazaly Saeed, Aziz Alanazi, Sharifa Alghamdi, Shirin Anil, Asaad Assiri
PURPOSE: To determine the socio-economic impact of gluten free diet (GFD) on Saudi children and their families. METHODS: A cross-sectional study was conducted in which an online questionnaire was sent to all families registered in the Saudi celiac patients support group. We included only children (age 18 years of age and younger) with biopsy-confirmed celiac disease (CD). RESULTS: A total of 113 children were included in the final analysis, the median age was 9...
September 2016: Pediatric Gastroenterology, Hepatology & Nutrition
Danyta I Tedjo, Agnieszka Smolinska, Paul H Savelkoul, Ad A Masclee, Frederik J van Schooten, Marieke J Pierik, John Penders, Daisy M A E Jonkers
Monitoring mucosal inflammation is crucial to prevent complications and disease progression in Crohn's disease (CD). Endoscopy is the current standard, but is invasive. Clinical activity scores and non-invasive biochemical markers do not correlate well with mucosal inflammation. Microbial perturbations have been associated with disease activity in CD. Therefore, we aimed to investigate its potential use to differentiate CD patients in remission from those with an exacerbation. From 71 CD patients repeated fecal samples were collected, resulting in 97 active disease and 97 remission samples based on a combination of biochemical and clinical parameters...
October 13, 2016: Scientific Reports
Manuel C Vallejo, Ahmed F Attaallah, Robert E Shapiro, Osama M Elzamzamy, Michael G Mueller, Warren S Eller
BACKGROUND: We aimed to determine the incidence of surgical site infection (SSI) after cesarean delivery (CD) and identify the risk factors in a rural population. METHODS: We identified 218 SSI patients by International Classification of Disease codes and matched them with 3131 parturients (control) from the electronic record database in a time-matched retrospective quality assurance analysis. RESULTS AND DISCUSSION: The incidence of SSI after CD was 7...
October 12, 2016: Journal of Anesthesia
Wan-Ru Sheng, Yue Chen, Shan-Shan Wang, Xiao-Li Wang, Ming-Lin Wang, Ru-Song Zhao
In this study, stable cadmium(II)-based metal-organic nanotubes (Cd-MONTs) were prepared and used as a coating material for solid-phase microextraction (SPME) of polychlorinated biphenyls (PCBs) from environmental water samples. The as-prepared Cd-MONT SPME coating material was characterized by thermal gravimetric analysis, scanning electron microscopy, and X-ray diffraction. The synthesized Cd-MONTs exhibited high thermal stability (385 °C) and excellent extraction performance toward PCBs. The important conditions were optimized systematically by the response surface method...
October 4, 2016: Analytical and Bioanalytical Chemistry
Anay Kumar Maurya, Deepak Parashar, T Satyanarayana
Thermophilc mold Sporotrichum thermophile secretes an acidstable and thermostable phytase, which finds application as a food and feed additive because of its adequate thermostability, acid stability, protease insensitivity and broad substrate spectrum. Low extracellular phytase production by the mold is a major bottleneck for its application on a commercial scale. We have successfully overcome this problem by constitutive secretary expression of codon optimized rStPhy under glyceraldehyde phosphate dehydrogenase (GAP) promoter in Pichia pastoris...
September 30, 2016: International Journal of Biological Macromolecules
Yaron Niv
BACKGROUND AND AIMS: The mucus layer of the intestinal tract is the main barrier between luminal microbes and the mucosa, and has an essential role in the body defense mechanisms. Previous research could not establish consistent results for mucin genes expression in Crohn's disease (CD) patients. In this meta-analysis we looked at the mucin expression in CD patients and compared it with healthy controls. METHOD: English medical literature searches were conducted for mucin expression in the mucosa of the ileum and colon of CD patients and compared it with normal mucosa...
September 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
D A Vassiliadi, M Balomenaki, A Asimakopoulou, E Botoula, M Tzanela, S Tsagarakis
CONTEXT: Cushing's disease (CD) has a significant relapse rate after successful transsphenoidal surgery (TSS). Many CD patients respond aberrantly to desmopressin testing (DT). Disappearance of this response post-surgery may suggest complete removal of abnormal corticotrophs and lower possibility of recurrence. OBJECTIVE: The utility of post-operative DT to predict long-term outcome compared to the widely used post-operative cortisol (Cort) level. DESIGN: Retrospective analysis...
September 23, 2016: Journal of Clinical Endocrinology and Metabolism
Nicole Wieghard, Solange Mongoue-Tchokote, J Isaac Young, Brett C Sheppard, V Liana Tsikitis
AIM: Limited data exist on Crohn's disease (CD)-associated small bowel adenocarcinoma [SBA]. A large-scale retrospective cohort study was conducted comparing the clinical features and outcome of Crohn's-associated SBA and de novo SBA. METHOD: Data for patients with small bowel adenocarcinoma was gathered from the 1992 to 2010 United States Surveillance, Epidemiology and End Results cancer registry (SEER)-Medicare linked database. 2,123 patients were identified, of whom 179 had CD-associated and 1,944 de novo SBA...
September 22, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
Nsikak O Abiaobo, Sifon Udi, Ofonmbuk I Obot
The concentration of five heavy metals; Cadmium (Cd), Copper (Cu), Lead (Pb), Mercury (Hg) and Zinc (Zn) in the tissues of periwinkle; Typanotonus fuscatus from Iko River Estuary were determined using UNICAM Solar Atomic Absorption Spectrophotometer 969 model. The results showed that Cd ranged from 68.83 - 130.5mg/kg with a mean value of 104.47±23.85mg/kg, Cu ranged from 34.9 - 73.62mg/kg with a mean value of 57.70±17.19mg/kg, Pb ranged between 54.27 - 102.54mg/kg with a mean value of 85.03±18.52mg/kg, Mercury ranged from 0...
September 22, 2016: Recent Patents on Biotechnology
Liqiang Ge, Long Cang, Jie Yang, Dongmei Zhou
With growing concerns on cadmium (Cd) contamination of rice grain from the public, the mechanism about the uptake and translocation of Cd in rice plant has been widely studied in recent years. However, the study about the effects of future warming on rice Cd accumulation was almost neglected. In the paper, hydroponic experiments of Cd exposure in growth chambers under different growth temperature (asymmetric and symmetric warming) were conducted to investigate how warming influenced Cd uptake and translocation in rice seedlings (6 liangyou 9368)...
September 19, 2016: Environmental Science and Pollution Research International
Guojian Liao, Yi Xu, Cheng Chen, Qianhua Wu, Renwei Feng, Junkang Guo, Ruigang Wang, Yongzhen Ding, Yang Sun, Yingming Xu, Wei Xia, Zhilian Fan, Liangyu Mo
Most current technologies can hardly simultaneously reduce the accumulation of arsenic (As) and cadmium (Cd) in crops. In this study, root application of selenite [Se (IV)] and selenate [Se (VI)] was used to assess their abilities to reduce the accumulation of As and Cd, and maintain the yields and quality of rice grains. The results show that Se (IV) showed a weaker ability than Se (VI) to maintain the grain contents of many essential elements, but a stronger ability to decrease As and Cd contents in rice grains, and maintain the yields, photosynthesis rate and stomatal conductance, and increase the grain contents of several amino acids (AAs), total Se, selenomethionine (SeMet) and selenocysteine (SeCys)...
December 1, 2016: Journal of Environmental Management
Silje Thorsvik, Jan Kristian Damås, Atle van Beelen Granlund, Trude Helen Flo, Kåre Bergh, Ann Elisabet Østvik, Arne Kristian Sandvik
BACKGROUND AND AIM: Accurate, non-invasive biomarkers are needed to diagnose and monitor inflammatory bowel disease (IBD). Neutrophil Gelatinase Associated Lipocalin (NGAL), also known as Lipocalin 2, is expressed in inflamed colonic epithelium and neutrophilic granulocytes. This study explores its properties as a biomarker in feces and plasma and, for the first time, compares fecal NGAL systematically with the existing fecal biomarker calprotectin. METHODS: NGAL was measured in feces from 73 patients with IBD, 21 patients with infectious enterocolitis, 21 patients with irritable bowel syndrome (IBS) and 23 healthy subjects using ELISA...
September 18, 2016: Journal of Gastroenterology and Hepatology
Sarah Bamberger, Christine Martinez Vinson, Damir Mohamed, Jérôme Viala, Jean-Claude Carel, Jean-Pierre Hugot, Dominique Simon
Inflammation contributes to growth failure associated with inflammatory bowel diseases. Anti-TNFα therapy induces sustained remission and short-term improvements in height velocity and/or height standard deviation score (H-SDS) patients with Crohn's disease. The purpose of this study was to evaluate growth and adult height in patients with Crohn's disease taking maintenance infliximab or adalimumab therapy.This university-hospital based retrospective study included 61 patients, with a median follow-up of 2...
2016: PloS One
Dane T Lamb, Mohammed Kader, Hui Ming, Liang Wang, Sedigheh Abbasi, Mallavarapu Megharaj, Ravi Naidu
Cadmium accumulates in plant tissues at low soil loadings and is a concern for human health. Yet at higher levels it is also of concern for ecological receptors. We determined Cd partitioning constants for 41 soils to examine the role of soil properties controlling Cd partitioning and plant uptake. From a series of sorption and dose response studies, transfer functions were developed for predicting Cd uptake in Cucumis sativa L. (cucumber). The parameter log Kf was predicted with soil pHca, logCEC and log OC...
September 12, 2016: Ecotoxicology
Qinchun Li, Xiaoyan Yang, Hongbin Wang, Haijuan Wang, Shujuan He
A field survey was conducted to evaluate soil metal pollution and endogenous trans-zeatin content in the leaves of plants growing at six sites in a metal-polluted area located in Gejiu, Yunnan, China. Five plant species were collected, and the physicochemical properties and concentrations of five metals in the soil were analyzed. The trans-zeatin content in plant leaves was measured by high-performance liquid chromatography. Based on the Nemerow pollution index, the six sites were classified into four levels of pollution (i...
September 9, 2016: Environmental Science and Pollution Research International
Nils-Olaf Huebner, Kathleen Dittmann, Vivien Henck, Christian Wegner, Axel Kramer
BACKGROUND: One important aspect in combatting resistance to antibiotics is to increase the awareness and knowledge by epidemiological studies. We therefore conducted a German-wide point-prevalence survey for multidrug resistant bacterial organisms (MDROs) and Clostridium difficile (CD) to assess the epidemiology and structure quality of infection control in German hospitals. METHOD: 1550 hospitals were asked to participate and to report surveillance data on the prevalence of Methicillin-resistant and Vancomycin resistant Staphylococcus aureus (MRSA, VRSA/GRSA), Vancomycin resistant Enterococcus faecalis/faecium (VRE), multiresistant strains of Escherichia coli (EC), Klebsiella spp...
2016: BMC Infectious Diseases
Janette Musilova, Julius Arvay, Alena Vollmannova, Tomas Toth, Jan Tomas
Due to its status as one of the most contaminated regions in Slovakia, 45 soil and plant samples were collected in the Middle Spis region. In soil, the exchangeable soil reaction, humus content and heavy metals content (Zn, Cd, Cu, Pb, Hg) were determined. Total content of heavy metals (TC-HMs) and content of mobile forms (MF-HMs) in soil, as well as metal content in plants, were determined by atomic absorption spectrometry. The concentration ranges for total Zn, Cd, Cu, Pb and Hg in soil were 33.1-953, 0.65-6...
October 2016: Bulletin of Environmental Contamination and Toxicology
Matthew Cauldwell, Kate Von Klemperer, Anselm Uebing, Lorna Swan, Philip J Steer, Michael Gatzoulis, Mark R Johnson
OBJECTIVE: To examine the duration of the passive and active parts of the second stage (SS) of labour in women with cardiac disease (CD) and to assess the adherence to antenatal care plans regarding timing of assisted delivery. Cardiac parameters were measured in a subset of women to investigate any differences between the passive and active SS of labour. STUDY DESIGN: Cohort study of 73 women with CD, classified into mWHO Class Groups I-IV. Women were matched with an equal number of women controlling for gestational age, maternal age (+/- five years), parity, use of regional anaesthesia, and spontaneous versus assisted delivery...
November 1, 2016: International Journal of Cardiology
Lucas M T Branco, Tamires Zanao, Thiago J De Rezende, Raphael F Casseb, Marcio F Balthazar, Susan C Woolley, Marcondes C França
Cognitive decline (CD) is common but often under-recognized in ALS due to the scarcity of adequate cognitive screening methods. In this scenario, the Amyotrophic Lateral Sclerosis Cognitive Behavioural Screen (ALS-CBS) is the most investigated instrument and presents high sensitivity to identify CD. Currently, there are no validated cognitive screening tools for ALS patients in the Brazilian population and little is known about the frequency of ALS related CD in the country. We assessed the accuracy of the Brazilian Portuguese version of ALS-CBS Cognitive Section (ALS-CBS-Br) for classifying the cognitive status of Brazilian patients compared to a standard neuropsychological battery, and estimated the prevalence of CD in the Brazilian ALS population...
August 18, 2016: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
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