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https://www.readbyqxmd.com/read/27900423/contamination-fractionation-and-biological-risk-related-to-metals-in-surface-sediments-from-the-largest-deep-freshwater-lake-in-china
#1
Hua-Bing Li, Yang-Guang Gu, Rong Wang, Hui-Bin Lu
The toxicity and mobility of metals in the environment are driven by their specific chemical forms and binding states. However, heavy metal fractionation in sediments from plateau deep lakes in China is rare. This study analyzed surface sediments collected from Fuxian Lake, the largest deep freshwater lake in China; parameters examined included total metal concentrations, chemical partitioning, and biological risk assessment. The average total concentrations (mg/kg) were 7.9 for Cd, 97.6 for Pb, 102.8 for Cr, 60...
November 29, 2016: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/27868331/patient-resilience-in-the-fracture-orthopaedic-rehabilitation-geriatric-environment
#2
Sabrina Kohler, Sze Ming Loh
OBJECTIVE: To explore the relationship between resilience and rehabilitation outcomes in older orthopaedic patients. METHODS: Geriatric rehabilitation patients admitted to a general metropolitan hospital following a fracture were interviewed face-to-face. Their resilience was assessed using the Connor-Davidson Resilience Scale (CD-RISC), and rehabilitation outcomes were assessed according to functional independence measure (FIM) gain, length of stay, discharge destination and mortality rate...
November 20, 2016: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/27865658/characterization-of-particulate-phase-polycyclic-aromatic-hydrocarbons-emitted-from-incense-burning-and-their-bioreactivity-in-raw264-7-macrophage
#3
Tzu-Ting Yang, Su-Chen Ho, Lu-Te Chuang, Hsiao-Chi Chuang, Ya-Ting Li, Jyun-Jie Wu
This study investigated the effects of particle-bound polycyclic aromatic hydrocarbons (PAHs) produced from burning three incense types on and their bioreactivity in the RAW 264.7 murine macrophage cell line. Gas chromatography/mass spectrometry was used to determine the levels of 16 identified PAHs. Macrophages were exposed to incense particle extracts at concentrations of 0, 3.125, 6.25, 12.5, 25, 50, and 100 μg/mL for 24 h. After exposure, cell viability and nitric oxide (NO) and inflammatory mediator [tumor necrosis factor (TNF)-α] production of the cells were examined...
January 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27852169/fatigue-in-a-population-based-cohort-of-patients-with-inflammatory-bowel-disease-20-years-after-diagnosis-the-ibsen-study
#4
Gert Huppertz-Hauss, Marte Lie Høivik, Lars-Petter Jelsness-Jørgensen, Randi Opheim, Magne Henriksen, Ole Høie, Øistein Hovde, Iril Kempski-Monstad, Inger Camilla Solberg, Jørgen Jahnsen, Geir Hoff, Bjørn Moum, Tomm Bernklev
OBJECTIVE: Fatigue is a major concern for patients with ulcerative colitis (UC) and Crohn's disease (CD), but evidence from population-based studies regarding fatigue in long-standing inflammatory bowel disease (IBD) patients is scarce. Our aims were to assess fatigue scores and the prevalence of chronic fatigue in IBD patients 20 years after diagnosis and to identify variables associated with fatigue in this cohort. METHODS: Twenty years after diagnosis, patients from a cohort with incident IBD were invited to a follow-up visit that included a structured interview, a clinical examination, laboratory tests and the Fatigue Questionnaire (FQ)...
November 17, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27848931/serum-albumin-and-c-reactive-protein-albumin-ratio-are-useful-biomarkers-of-crohn-s-disease-activity
#5
Guangming Qin, Jiangfeng Tu, Lingang Liu, Laisheng Luo, Jiaqi Wu, Lisha Tao, Chenjing Zhang, Xiaoge Geng, Xiaojun Chen, Xinbo Ai, Bo Shen, Wensheng Pan
BACKGROUND Serum albumin (ALB) may be low during acute inflammation, but it is also affected by nutritional status. Therefore, we hypothesized that ALB and the C-reactive protein/ALB ratio (CRP/ALB) may be associated with disease activity in patients with Crohn's disease (CD). MATERIAL AND METHODS Altogether, 100 patients with CD and 100 age- and sex-matched healthy volunteers were retrospectively enrolled in the current study. The patients with CD were subdivided into patients with active disease (Crohn's Disease Activity Index >150) and those in remission...
November 16, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27812912/levels-of-metals-in-kidney-liver-and-muscle-tissue-and-their-influence-on-the-fitness-for-the-consumption-of-wild-boar-from-western-slovakia
#6
Jozef Gašparík, Łukasz J Binkowski, Andrej Jahnátek, Peter Šmehýl, Milan Dobiaš, Norbert Lukáč, Martyna Błaszczyk, Magdalena Semla, Peter Massanyi
Due to environmental pollution, wild animals are exposed to various pollutants. Some game animals, such as wild boars are used by people for food, but their meat is not evaluated regarding pollution transfer, since they are unavailable on the official market. The aim of this paper is to present the concentrations of chosen metals (Cd, Co, Cu, Hg, Pb, and Zn) in the kidneys, liver, and muscles of wild boars (n = 40) hunted in eastern Slovakia, as derivatives of physiological distribution and anthropogenic pollution...
November 3, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27810536/seasonal-variations-in-the-blood-concentration-of-selected-heavy-metals-in-sheep-and-their-effects-on-the-biochemical-and-hematological-parameters
#7
Anton Kovacik, Julius Arvay, Eva Tusimova, Lubos Harangozo, Eva Tvrda, Katarina Zbynovska, Peter Cupka, Stefania Andrascikova, Jan Tomas, Peter Massanyi
The main objective of this study was to assess the concentration of various heavy metals (Cd, Pb, Zn, Cu, Hg) in the blood of sheep, followed by biochemical and hematological analysis in order to reveal possible associations. Blood was collected in two different seasons: winter (fed by fodder) and spring (grazing animals). The higher concentrations of Pb (p < 0.01), Cu (p < 0.05) and Hg, but lower of Cd and Zn were found in spring. Evaluation of the biochemical and hematological parameters during different seasons showed a possible environmental effect on the health of animals...
October 27, 2016: Chemosphere
https://www.readbyqxmd.com/read/27803867/prevalence-and-characteristics-of-ophthalmological-extra-intestinal-manifestations-in-chinese-patients-with-inflammatory-bowel-disease
#8
Ying-Chao Li, Wei-Zhi Li, Chang-Rui Wu, Yun Feng, Li Ren, Chen Mi, Yang Li
AIM: To investigate the prevalence of ophthalmological extra-intestinal manifestations (O-EIMs) in Chinese patients with inflammatory bowel disease (IBD) and to identify risk factors for the development of O-EIMs. METHODS: The study population consisted of Chinese patients with a definite diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) in a large teaching hospital between January 1995 and December 2014. Demographic and clinical characteristics of patients were extracted retrospectively...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27785711/long-term-disease-course-and-pregnancy-outcomes-in-women-with-inflammatory-bowel-disease-an-indian-cohort-study
#9
Rajesh Kumar Padhan, Saurabh Kedia, Sushil Kumar Garg, Sawan Bopanna, V Pratap Mouli, Rajan Dhingra, Govind Makharia, Vineet Ahuja
BACKGROUND: The literature on interaction between pregnancy and inflammatory bowel disease (IBD) is inconsistent, and there are no reports on this aspect from Asia. This study evaluated the impact both IBD and pregnancy have on each other in a large cohort of Indian patients. METHODS: In total, 514 females with ulcerative colitis (UC) or Crohn's disease (CD) aged between 18 and 45 years attending IBD clinic, at our institute, from July 2004 to July 2013 were screened, and patients with data on pregnancy status were included (n = 406)...
October 26, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27785311/obesity-and-outcome-of-crohn-s-associated-perianal-fistula-surgery-a-case-control-study
#10
Ashish Manne, Ali S Khan, Talha A Malik
BACKGROUND: Evidence suggests that obesity (body mass index (BMI) > 30 kg/m(2)) adversely affects several outcomes in Crohn's disease (CD). CD-associated perianal fistula (CDPF) represents a debilitating phenotype with a clinical course that may be affected by obesity. We hypothesized that obese CD patients would be more likely to have poor outcomes following CDPF surgery. METHODS: We designed a case-control study of CD patients who underwent surgery for CDPF between 2000 and 2013 with documented pre-operative BMI and post-operative outcome...
December 2015: Gastroenterology Research
https://www.readbyqxmd.com/read/27761727/the-role-of-cd90-in-the-differential-diagnosis-of-pleural-malignant-mesothelioma-pulmonary-carcinoma-and-comparison-with-calret%C3%A4-n%C3%A4-n
#11
Nurhan Sahin, Ayse Nur Akatli, Muhammet Reha Celik, Hakkı Ulutas, Emine Turkmen Samdanci, Cemil Colak
Pleural Malignant Mesothelioma (MM) is a fatal disease that has been associated with asbestos exposure. Differential diagnosis between the pleural infiltration of pulmonary carcinomas and MM is rather difficult particularly for epitheloid type mesothelioma.We aimed to investigate the utility of CD90, a cancer stem cell marker, in the differential diagnosis of MM and lung carcinoma, its prognostic significance and compare its value with that of Calretinin. Ninety pathology specimens including MM (n:30), pulmonary adenocarcinoma (n:30) and pulmonary squamous cell carcinoma (n:30) were used in this study...
October 19, 2016: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/27738597/socioeconomic-impacts-of-gluten-free-diet-among-saudi-children-with-celiac-disease
#12
Ahmed Sarkhy, Mohammad I El Mouzan, Elshazaly Saeed, Aziz Alanazi, Sharifa Alghamdi, Shirin Anil, Asaad Assiri
PURPOSE: To determine the socio-economic impact of gluten free diet (GFD) on Saudi children and their families. METHODS: A cross-sectional study was conducted in which an online questionnaire was sent to all families registered in the Saudi celiac patients support group. We included only children (age 18 years of age and younger) with biopsy-confirmed celiac disease (CD). RESULTS: A total of 113 children were included in the final analysis, the median age was 9...
September 2016: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/27734914/the-fecal-microbiota-as-a-biomarker-for-disease-activity-in-crohn-s-disease
#13
Danyta I Tedjo, Agnieszka Smolinska, Paul H Savelkoul, Ad A Masclee, Frederik J van Schooten, Marieke J Pierik, John Penders, Daisy M A E Jonkers
Monitoring mucosal inflammation is crucial to prevent complications and disease progression in Crohn's disease (CD). Endoscopy is the current standard, but is invasive. Clinical activity scores and non-invasive biochemical markers do not correlate well with mucosal inflammation. Microbial perturbations have been associated with disease activity in CD. Therefore, we aimed to investigate its potential use to differentiate CD patients in remission from those with an exacerbation. From 71 CD patients repeated fecal samples were collected, resulting in 97 active disease and 97 remission samples based on a combination of biochemical and clinical parameters...
October 13, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27734126/independent-risk-factors-for-surgical-site-infection-after-cesarean-delivery-in-a-rural-tertiary-care-medical-center
#14
Manuel C Vallejo, Ahmed F Attaallah, Robert E Shapiro, Osama M Elzamzamy, Michael G Mueller, Warren S Eller
BACKGROUND: We aimed to determine the incidence of surgical site infection (SSI) after cesarean delivery (CD) and identify the risk factors in a rural population. METHODS: We identified 218 SSI patients by International Classification of Disease codes and matched them with 3131 parturients (control) from the electronic record database in a time-matched retrospective quality assurance analysis. RESULTS AND DISCUSSION: The incidence of SSI after CD was 7...
October 12, 2016: Journal of Anesthesia
https://www.readbyqxmd.com/read/27704175/cadmium-ii-based-metal-organic-nanotubes-as-solid-phase-microextraction-coating-for-ultratrace-level-analysis-of-polychlorinated-biphenyls-in-seawater-samples
#15
Wan-Ru Sheng, Yue Chen, Shan-Shan Wang, Xiao-Li Wang, Ming-Lin Wang, Ru-Song Zhao
In this study, stable cadmium(II)-based metal-organic nanotubes (Cd-MONTs) were prepared and used as a coating material for solid-phase microextraction (SPME) of polychlorinated biphenyls (PCBs) from environmental water samples. The as-prepared Cd-MONT SPME coating material was characterized by thermal gravimetric analysis, scanning electron microscopy, and X-ray diffraction. The synthesized Cd-MONTs exhibited high thermal stability (385 °C) and excellent extraction performance toward PCBs. The important conditions were optimized systematically by the response surface method...
November 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27697488/bioprocess-for-the-production-of-recombinant-hap-phytase-of-the-thermophilic-mold-sporotrichum-thermophile-and-its-structural-and-biochemical-characteristics
#16
Anay Kumar Maurya, Deepak Parashar, T Satyanarayana
Thermophilc mold Sporotrichum thermophile secretes an acidstable and thermostable phytase, which finds application as a food and feed additive because of its adequate thermostability, acid stability, protease insensitivity and broad substrate spectrum. Low extracellular phytase production by the mold is a major bottleneck for its application on a commercial scale. We have successfully overcome this problem by constitutive secretary expression of codon optimized rStPhy under glyceraldehyde phosphate dehydrogenase (GAP) promoter in Pichia pastoris...
September 30, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27689200/mucin-genes-expression-in-the-intestine-of-crohn-s-disease-patients-a-systematic-review-and-meta-analysis
#17
REVIEW
Yaron Niv
BACKGROUND AND AIMS: The mucus layer of the intestinal tract is the main barrier between luminal microbes and the mucosa, and has an essential role in the body defense mechanisms. Previous research could not establish consistent results for mucin genes expression in Crohn's disease (CD) patients. In this meta-analysis we looked at the mucin expression in CD patients and compared it with healthy controls. METHOD: English medical literature searches were conducted for mucin expression in the mucosa of the ileum and colon of CD patients and compared it with normal mucosa...
September 2016: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/27662440/the-desmopressin-test-predicts-better-than-basal-cortisol-the-long-term-surgical-outcome-of-cushing-s-disease
#18
D A Vassiliadi, M Balomenaki, A Asimakopoulou, E Botoula, M Tzanela, S Tsagarakis
CONTEXT: Cushing's disease (CD) has a significant relapse rate after successful transsphenoidal surgery (TSS). Many CD patients respond aberrantly to desmopressin testing (DT). Disappearance of this response post-surgery may suggest complete removal of abnormal corticotrophs and lower possibility of recurrence. OBJECTIVE: The utility of post-operative DT to predict long-term outcome compared to the widely used post-operative cortisol (Cort) level. DESIGN: Retrospective analysis...
September 23, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27659145/prognosis-of-small-bowel-adenocarcinoma-in-crohn-s-disease-compares-favourably-with-de-novo-small-bowel-adenocarcinoma
#19
Nicole Wieghard, Solange Mongoue-Tchokote, J Isaac Young, Brett C Sheppard, V Liana Tsikitis
AIM: Limited data exist on Crohn's disease (CD)-associated small bowel adenocarcinoma [SBA]. A large-scale retrospective cohort study was conducted comparing the clinical features and outcome of Crohn's-associated SBA and de novo SBA. METHOD: Data for patients with small bowel adenocarcinoma was gathered from the 1992 to 2010 United States Surveillance, Epidemiology and End Results cancer registry (SEER)-Medicare linked database. 2,123 patients were identified, of whom 179 had CD-associated and 1,944 de novo SBA...
September 22, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27659131/heavy-metal-concentration-in-periwinkle-tympanotomus-fuscatus-in-iko-river-estuary-nigeria
#20
Nsikak O Abiaobo, Sifon Udi, Ofonmbuk I Obot
The concentration of five heavy metals; Cadmium (Cd), Copper (Cu), Lead (Pb), Mercury (Hg) and Zinc (Zn) in the tissues of periwinkle; Typanotonus fuscatus from Iko River Estuary were determined using UNICAM Solar Atomic Absorption Spectrophotometer 969 model. The results showed that Cd ranged from 68.83 - 130.5mg/kg with a mean value of 104.47±23.85mg/kg, Cu ranged from 34.9 - 73.62mg/kg with a mean value of 57.70±17.19mg/kg, Pb ranged between 54.27 - 102.54mg/kg with a mean value of 85.03±18.52mg/kg, Mercury ranged from 0...
September 22, 2016: Recent Patents on Biotechnology
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