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CD 73

Joshua D Dahlke, Jeffrey D Sperling, Phinnara Has, Todd R Lovgren, Brendan D Connealy, Dwight J Rouse
OBJECTIVE:  Given that recent consensus guidelines established to decrease cesarean delivery (CD) rates use 6 cm to define the onset of the active phase of labor, our objective was to evaluate maternal and neonatal outcomes after CD for the indication of arrest of dilation at 4 to 5 cm compared with ≥ 6 cm. STUDY DESIGN:  We performed a secondary analysis using data from the Maternal Fetal-Medicine Units Network Cesarean Registry. We included nulliparous women with term, singleton, vertex gestations who underwent primary CD for arrest of dilation...
April 24, 2018: American Journal of Perinatology
Antonio Rispo, Nicola Imperatore, Anna Testa, Olga Maria Nardone, Gaetano Luglio, Nicola Caporaso, Fabiana Castiglione
Background and aims: The postoperative course of Crohn's disease (CD) is best predicted by ileocolonoscopy. Ultrasonography (US) has been proposed as indicator for postsurgical recurrence (PSR), but further confirmation is needed. We performed a systemic review with meta-analysis to assess the pooled diagnostic accuracy of US in the evaluation of PSR. Methods: The systematic review was performed in PubMed/MEDLINE, EMBASE, SCOPUS, and Cochrane databases to identify studies assessing the US accuracy in PSR diagnosis...
April 23, 2018: Inflammatory Bowel Diseases
Jie Zhang, Shiyong Yang, Hongfei Yang, Yongjie Huang, Liming Zheng, Jing Yuan, Shoubiao Zhou
Four gramineous energy plants, Miscanthus sacchariflorus, M. floridulus, Phragmites australis, and Arundo donax were grown on copper tailings in the field for four years. Their phytoremediation potential was examined in terms of their effects on the fractions of heavy metals and soil enzyme activities. Results showed that plantation of these four gramineous plants has improved the proportion of organic material (OM)-binding fraction of heavy metals in copper tailings as a whole, and reduced the proportion of exchangeable and residual fractions...
May 12, 2018: International Journal of Phytoremediation
Emmanuel Gbenga Olumayede, Thompson Faraday Ediagbonya
The paper investigates the hypothesis that biotoxicities of trace metals depend not only on the concentration as expressed by the total amount, but also on their geochemical fractions and bioavailability. Airborne particles were collected using SKC Air Check XR 5000 high volume Sampler at a human breathing height of 1.5-2.0 meters, during the dry season months from November 2014 to March 2015 at different locations in Akure (7°10'N and 5°15'E). The geochemical-based sequential extractions were performed on the particles using a series of increasingly stringent solutions selected to extract metals (Cd, Cu, Cr, Ni, Pb, Zn, and Mn) into four operational geochemical phases-exchangeable, reducible, organic, and residual-and then quantified using an Atomic Absorption Spectrophotometer...
2018: TheScientificWorldJournal
Gaspare Drago, Cinzia Perrino, Silvia Canepari, Silvia Ruggieri, Luca L'Abbate, Valeria Longo, Paolo Colombo, Daniele Frasca, Martin Balzan, Giuseppina Cuttitta, Gianluca Scaccianoce, Giuseppe Piva, Salvatore Bucchieri, Mario Melis, Giovanni Viegi, Fabio Cibella, Martin Balzan, David Bilocca, Charles Borg, Stephen Montefort, Christopher Zammit, Salvatore Bucchieri, Fabio Cibella, Paolo Colombo, Giuseppina Cuttitta, Gaspare Drago, Giuliana Ferrante, Luca L'Abbate, Stefania La Grutta, Valeria Longo, Mario R Melis, Silvia Ruggieri, Giovanni Viegi, Remo Minardi, Giuseppe Piva, Rosaria Ristagno, Gianfranco Rizzo, Gianluca Scaccianoce
Cigarette smoke is the main source of indoor chemical and toxic elements. Cadmium (Cd), Thallium (Tl), Lead (Pb) and Antimony (Sb) are important contributors to smoke-related health risks. Data on the association between Rare Earth Elements (REE) Cerium (Ce) and Lanthanum (La) and domestic smoking are scanty. To evaluate the relationship between cigarette smoke, indoor levels of PM2.5 and heavy metals, 73 children were investigated by parental questionnaire and skin prick tests. The houses of residence of 41 "cases" and 32 "controls" (children with and without respiratory symptoms, respectively) were evaluated by 48-h PM2...
April 16, 2018: Environmental Research
Marla C Dubinsky, Raymond K Cross, William J Sandborn, Millie Long, Xue Song, Nianwen Shi, Yao Ding, Samantha Eichner, Brandee Pappalardo, Arijit Ganguli, Anthony Wang
Background: Extra-intestinal manifestations (EIMs) can impact morbidity in patients with inflammatory bowel diseases (IBD; Crohn's disease [CD] and ulcerative colitis [UC]). This study compared incidence rates of EIMs in patients with moderate to severe IBD receiving gut-selective vedolizumab (VDZ) vs those receiving systemic anti-tumor necrosis factor (anti-TNF) therapies. Methods: Adult IBD patients receiving VDZ or anti-TNFs were identified from the MarketScan claims database from September 28, 2012, through September 30, 2016...
April 13, 2018: Inflammatory Bowel Diseases
Xiuqing Zhai, Zhongwu Li, Bin Huang, Ninglin Luo, Mei Huang, Qiu Zhang, Guangming Zeng
The remediation of heavy metal-contaminated soils is a great challenge for global environmental sciences and engineering. To control the ecological risks of heavy metal-contaminated soil more effectively, the present study focused on the combination of soil washing (with FeCl3 ) and in situ immobilization (with lime, biochar, and black carbon). The results showed that the removal rate of Cd, Pb, Zn, and Cu was 62.9%, 52.1%, 30.0%, and 16.7%, respectively, when washed with FeCl3 . After the combined remediation (immobilization with 1% (w/w) lime), the contaminated soils showed 36...
April 13, 2018: Science of the Total Environment
Yangyang Wang, Fangfang Li, Jian Song, Ruiyang Xiao, Lin Luo, Zhihui Yang, Liyuan Chai
Red mud (RM) was used to remediate heavy metal-contaminated soils. Experiments with two different dosages of RM added to soils were carried out in this study. It was found that soil pH increased 0.3 and 0.5 unit with the dosage of 3 and 5% (wt%), respectively. At the dosage of 5%, the highest stabilization efficiencies for Cd, Pb, Cu and Zn reached 67.95, 64.21, 43.73 and 63.73%, respectively. The addition of RM obviously transferred Cd from the exchangeable fraction to the residual fraction. Meanwhile, in comparison with the control (no RM added), it reduced 24...
April 12, 2018: Environmental Geochemistry and Health
Liang Fu, Hualin Xie, Shuyun Shi
The concentrations of trace elements (Cr, Ni, As, Cd, Hg, and Pb) in Zanthoxylum bungeanum Maxim. essential oil (ZBMEO) were determined by inductively coupled plasma tandem mass spectrometry. The ZBMEO sample was directly analyzed after simple dilution with n-hexane. Aiming for a relatively high vapor pressure of n-hexane and its resultant loading on plasma, we used a narrow injector torch and optimized plasma radio frequency power and carrier gas flow to ensure stable operation of the plasma. An optional gas flow of 20% O2 in Ar was added to the carrier gas to prevent the incomplete combustion of highly concentrated organic carbon in plasma and the deposition of carbon on the sampling and skimmer cone orifices...
April 12, 2018: Analytical and Bioanalytical Chemistry
Merih Tepeoğlu, Gonca Özgün, M Zeyneb Tunca, Tugan Tezcaner, B Handan Özdemir
OBJECTIVE: The clinical behavior of gastrointestinal stromal tumors is divergent. The aim of the present study was to define the clinicopathological features that determine the patient's outcome. MATERIAL AND METHOD: Sixty-five gastrointestinal stromal tumors were reviewed with their histological, immunohistochemical and clinical features and compared with their clinical outcome statistically. RESULTS: Tumors were located in the stomach (n=39, 60%), small intestine (n=22, 33...
April 9, 2018: Türk Patoloji Dergisi
Soumik Mitra, Krishnendu Pramanik, Pallab Kumar Ghosh, Tithi Soren, Anumita Sarkar, Ramendra Sundar Dey, Sanjeev Pandey, Tushar Kanti Maiti
Application of heavy metal resistant plant growth promoting rhizobacteria has an important role as they help to evade metal-induced toxicity in plants on one hand and enhance plant growth on the other. The present study is therefore focused on the characterization of a cadmium resistant bacterial strain isolated from heavy metal contaminated rhizospheric soil designated as S8. This S8 strain was selected in terms of cadmium resistance and plant growth promoting traits. Moreover, it also showed resistance to lead and arsenic to a considerable extent...
May 2018: Microbiological Research
Jonathan P Robson, Pavlo Kokhanenko, Jean K Marshall, Anthony R Phillips, Jan van der Linden
Tissue perfusion during surgery is important in reducing surgical site infections and promoting healing. This study aimed to determine if insufflation of the open abdomen with heated, humidified (HH) carbon dioxide (CO2) increased visceral tissue perfusion and core body temperature during open abdominal surgery in a rodent model. Using two different rodent models of open abdominal surgery, visceral perfusion and core temperature were measured. Visceral perfusion was investigated using a repeated measures crossover experiment with rodents receiving the same sequence of two alternating treatments: exposure to ambient air (no insufflation) and insufflation with HH CO2...
2018: PloS One
Babak Djahed, Mahmoud Taghavi, Mehdi Farzadkia, Samira Norzaee, Mohammad Miri
An investigation of some heavy metals content in rice (Oryza sativa) and associated health risks was carried out for residents of Iranshahr city, Iran. Average daily rice consumption of the citizens and most widely used rice brands in the market of Iranshahr were determined using a questionnaire. Besides, the concentration of heavy metals in the gathered rice samples was measured by inductively coupled plasma mass spectrometry (ICP-MS). Monte Carlo uncertainty simulation was utilized in conducting exposure assessment and investigating the non-carcinogenic effects of the studied elements as well as the carcinogenic effect of As...
March 30, 2018: Food and Chemical Toxicology
Hongyu Chen, Jinjin Zhang, Jinwei Ren, Wenzhao Wang, Weiping Xiong, Yaodong Zhang, Li Bao, Hongwei Liu
Ganoderma leucocontextum is a well-known medicinal mushroom cultivated in the Tibet Plateau of China. Chemistry investigation on the fruiting bodies of this mushroom resulted in the isolation of sixteen secondary metabolites including three new lanostane triterpenes, ganoleucoins Q-S (1-3), as well as thirteen known compounds (4-16). The structures of compounds 1-3 were determined by NMR, MS, CD spectral analysis and chemical derivation method. The neuroprotective effects of compounds 1-16 were tested on PC12 cells...
March 30, 2018: Chemistry & Biodiversity
P Tulayakul, R Mingkhwan, H Hananantachai, R Netvichian, S Khaodhiar, T Songserm
The cross-sectional study of heavy metals and aflatoxins was conducted by studying duck egg, blood, liver, feed, and water samples from 11 free grazing farms. The duck feed, soil, and rice samples were lower than the standard limit for aflatoxins at 20 ng g-1 . The highest levels of aflatoxin were detected in the liver, intestine, and egg yolk; these were 3.04, 1.73, and 4.56 ng g-1 respectively, while the average levels were 1.6 ± 0.73, 1.31 ± 0.23, and 1.87 ± 0.99 ng g-1 , respectively...
March 29, 2018: Biological Trace Element Research
Aliya Naz, Abhiroop Chowdhury, Brijesh Kumar Mishra, K Karthikeyan
This study accessed the levels of Cd, Cr, Fe, Mn, Ni, Pb and Zn concentration in soils of different locations (mine, roadside, agricultural and control sites) of Sukinda chromite mine (the India's largest Chromite mine and listed among the world's ten most polluted regions). Geo-accumulation (Igeo ) index indicates that the mine, agricultural and roadside soils are 'heavily to extremely contaminated' due to Cr, Ni, Pb and Cd, hence human residing/working in this region can have health hazards due to contaminated soil via different exposure pathways...
March 26, 2018: Environmental Geochemistry and Health
Masatsugu Ono, Shoichiro Horita, Yumi Sato, Yayoi Nomura, So Iwata, Norimichi Nomura
Tumor necrosis factor α (TNFα) is a proinflammatory cytokine, and elevated levels of TNFα in serum are associated with various autoimmune diseases, including rheumatoid arthritis (RA), ankylosing spondylitis (AS), Crohn's disease (CD), psoriasis and systemic lupus erythaematosus. TNFα performs its pleiotropic functions by binding to two structurally distinct transmembrane receptors, TNF receptor (TNFR) 1 and TNFR2. Antibody-based therapeutic strategies that block excessive TNFα signaling have been shown to be effective in suppressing such harmful inflammatory conditions...
March 25, 2018: Protein Science: a Publication of the Protein Society
Majid Kermani, Mahdi Farzadkia, Roshanak Rezaei Kalantari, Zohreh Bahmani
The aim of this study was to evaluate the concentration of PM2.5 particles, potential sources, and determination of health risk assessment of heavy metals in various parts of composting facilities of Tehran's Kahrizak. A total of 60 PM2.5 particle samples were collected every 3 days from January to March 2016. To analyze the heavy metals, inductively coupled plasma atomic emission spectroscopy (ICP-AES) was applied. SEM-EDX analysis indicated that metals of Al, Si, Mg, Na, Au, S, Ca, K, and Co were dominant in the structure of particles...
March 25, 2018: Environmental Science and Pollution Research International
Amey Dilip Sonavane, Pratibha Sonawane, Deepak N Amarapurkar
OBJECTIVES: To identify similarities and differences between the pediatric-onset and adult-onset Inflammatory Bowel Disease (IBD) based cohorts and further characterize the pediatric cohort. METHODS: A retrospective analysis of pediatric patients attending the tertiary referral care gastroenterology center from 2004 to 2016 was conducted. All the patients were clinically evaluated, investigated and followed up at the centre. RESULTS: Sixty five patients with pediatric IBD were compared with 216 patients with adult-onset IBD...
March 23, 2018: Indian Journal of Pediatrics
Yanni Jiao, Jindong Chen, Wei Li, Yongjun Liu, Chenglong Xin, Luping Yang
Determination of ten metal levels in 160 squid samples caught from offshore and the oceanic fishing locations by ICP-MS was made. The mean metal concentration in the squid muscles decreasing in the order of: Zn, Fe, Cu, As, Mn, Se, Cd, Pb, Cr and Ni. Metal concentrations in the squids were assessed for human uses according to provisional tolerable weekly intake (PTWI) and provisional tolerable daily intake (PTDI)·The estimated hazard quotients for the individual metals from squids were found in accordance to the following sequence: As > Cd > Cu > Se > Cr > Zn > Pb > Fe > Mn > Ni, with the greatest hazard upon human health coming primarily from As (1...
March 2018: Marine Pollution Bulletin
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