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https://www.readbyqxmd.com/read/28073650/the-utilisation-of-one-district-hospital-emergency-department-by-people-with-parkinson-s-disease
#1
Marion Harris, Margaret Fry
BACKGROUND: Parkinson's disease (PD) is the second most common neurodegenerative disorder in Australia and the economic burden is more than $8.3 billion a year and predicted to escalate. However, little is known of the trends and characteristics of people with Parkinson's disease presenting to emergency departments (ED). METHOD: The study design was a 12 month retrospective medical record audit. The study was conducted in one metropolitan 300 bed district hospital in an outer suburb of Sydney...
January 7, 2017: Australasian Emergency Nursing Journal: AENJ
https://www.readbyqxmd.com/read/28073241/prognostic-value-of-total-triiodothyronine-and-free-thyroxine-levels-for-the-heart-failure-in-patients-with-acute-myocardial-infarction
#2
Min Gyu Kang, Jong Ryeal Hahm, Kye-Hwan Kim, Hyun-Woong Park, Jin-Sin Koh, Seok-Jae Hwang, Jin-Yong Hwang, Jong Hwa Ahn, Yongwhi Park, Young-Hoon Jeong, Jeong Rang Park, Choong Hwan Kwak
Background/Aims: Although a low triiodothyronine (T3) state is closely associated with heart failure (HF), it is uncertain whether total T3 levels on admission is correlated with the clinical outcomes of acute myocardial infarction (AMI). The aim of this study is to investigate the prognostic value of total T3 levels for major adverse cardiovascular and cerebrovascular events (MACCEs) in patients with AMI undergone percutaneous coronary intervention (PCI). Methods: A total of 765 PCI-treated AMI patients (65...
January 11, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28062626/c-type-natriuretic-peptides-in-coronary-disease
#3
Timothy C R Prickett, Robert N Doughty, Richard W Troughton, Chris M Frampton, Gillian A Whalley, Chris J Ellis, Eric A Espiner, A Mark Richards
AIMS: C-type natriuretic peptide (CNP) is a paracrine growth factor expressed in the vascular endothelium. Although upregulated in atheromatous arteries, the predictive value of plasma CNP products for outcome in coronary disease is unknown. This study aimed to compare the prognostic value of plasma CNP products with those of other natriuretic peptides in individuals with coronary artery disease, and investigate their associations with cardiac and renal function. METHODS AND RESULTS: Plasma concentrations of CNP and amino-terminal proCNP (NT-proCNP) were measured at baseline in 2129 individuals after an index acute coronary syndrome admission and related to cardiac and renal function, other natriuretic peptides [atrial NP (ANP) and B-type NP (BNP)] and prognosis (primary end point, mortality; secondary end point, cardiac readmission)...
January 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28053181/comparison-of-risk-scoring-systems-for-patients-presenting-with-upper-gastrointestinal-bleeding-international-multicentre-prospective-study
#4
Adrian J Stanley, Loren Laine, Harry R Dalton, Jing H Ngu, Michael Schultz, Roseta Abazi, Liam Zakko, Susan Thornton, Kelly Wilkinson, Cristopher J L Khor, Iain A Murray, Stig B Laursen
OBJECTIVE:  To compare the predictive accuracy and clinical utility of five risk scoring systems in the assessment of patients with upper gastrointestinal bleeding. DESIGN:  International multicentre prospective study. SETTING:  Six large hospitals in Europe, North America, Asia, and Oceania. PARTICIPANTS:  3012 consecutive patients presenting over 12 months with upper gastrointestinal bleeding. MAIN OUTCOME MEASURES:  Comparison of pre-endoscopy scores (admission Rockall, AIMS65, and Glasgow Blatchford) and post-endoscopy scores (full Rockall and PNED) for their ability to predict predefined clinical endpoints: a composite endpoint (transfusion, endoscopic treatment, interventional radiology, surgery, or 30 day mortality), endoscopic treatment, 30 day mortality, rebleeding, and length of hospital stay...
January 4, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28004493/economic-evaluation-of-nasogastric-versus-intravenous-hydration-in-infants-with-bronchiolitis
#5
Ed Oakley, Rob Carter, Bridie Murphy, Meredith Borland, Jocelyn Neutze, Jason Acworth, David Krieser, Stuart Dalziel, Andrew Davidson, Susan Donath, Kim Jachno, Mike South, Franz E Babl
OBJECTIVE: Bronchiolitis is the most common lower respiratory tract infection in infants and the leading cause of hospitalisation. We aimed to assess whether intravenous hydration (IVH) was more cost-effective than nasogastric hydration (NGH) as a planned secondary economic analysis of a randomised trial involving 759 infants (aged 2-12 months) admitted to hospital with a clinical diagnosis of bronchiolitis and requiring non-oral hydration. No Australian cost data exist to aid clinicians in decision-making around interventions in bronchiolitis...
December 22, 2016: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/27994354/role-of-brain-natriuretic-peptide-as-a-novel-prognostic-biomarker-in-acute-ischemic-stroke
#6
Bindu Menon, Krishnana Ramalingam, Jyoti Conjeevaram, K Munisusmitha
AIM: We investigated to study the prognostic importance of brain natriuretic peptide (BNP) in ischemic stroke. MATERIALS AND METHODS: We prospectively enrolled 100 patients with acute ischemic stroke and measured plasma BNP levels and compared with age- and sex-matched healthy controls. Risk factors, biochemical parameters, lipid profile, carotid and vertebral Doppler, imaging, and cardiac evaluation were done. Stroke severity was assessed by the National Institutes of Health Stroke Scale (NIHSS) score on admission and functional disability by Barthel Index (BI) at 3 months...
October 2016: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/27991996/simple-prediction-model-for-unfavorable-outcome-in-ischemic-stroke-after-intravenous-thrombolytic-therapy
#7
Daniel Amitrano, Ivan Rocha Ferreira da Silva, Bernardo B Liberato, Valéria Batistella, Janaina Oliveira, Osvaldo J M Nascimento
Objective: We aimed to develop a model to predict unfavorable outcome in patients with acute ischemic stroke treated with intravenous thrombolytic therapy (IVT), based on simple variables present on admission. Methods: Retrospective analysis of acute ischemic stroke patients treated with IVT in a hospital in Rio de Janeiro. Clinical and radiographic variables were selected for analysis. Multivariate logistic regression was used to develop a predictive model. Results: We analyzed a total of 82 patients...
December 2016: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/27990628/action-plans-with-brief-patient-education-for-exacerbations-in-chronic-obstructive-pulmonary-disease
#8
REVIEW
Maxwell Howcroft, E Haydn Walters, Richard Wood-Baker, Julia Ae Walters
BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) are a major driver of decline in health status and impose high costs on healthcare systems. Action plans offer a form of self-management that can be delivered in the outpatient setting to help individuals recognise and initiate early treatment for exacerbations, thereby reducing their impact. OBJECTIVES: To compare effects of an action plan for COPD exacerbations provided with a single short patient education component and without a comprehensive self-management programme versus usual care...
19, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27943327/videotaping-of-surgical-procedures-and-outcomes-following-extraperitoneal-laparoscopic-radical-prostatectomy-for-clinically-localized-prostate-cancer
#9
Catherine Paterson, Sarah McLuckie, Chin Yew-Fung, Benjie Tang, Stephen Lang, Ghulam Nabi
BACKGROUND: Video-recording of emerging minimally invasive surgical procedures is likely to become an integral component of patient record-keeping in the future for prostate cancer treatment. No prior work has shown the impact of videotaping of laparoscopic prostatectomy on patient outcomes. Our aim was to determine correlation between independent peer review of videotaping quality scores of extraperitoneal laparoscopic prostatectomy (ELRP) with complications, re-admissions, functional, and early oncological outcomes...
December 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27916210/heart-type-fatty-acid-binding-protein-in-the-assessment-of-acute-pulmonary-embolism
#10
Hai-Yan Qian, Ji Huang, Yue-Jin Yang, Yan-Min Yang, Zhi-Zhong Li, Jing-Mei Zhang
OBJECTIVE: To explore the predictive value of heart-type fatty acid binding protein (H-FABP) in the stratification and prognosis of patients with acute pulmonary embolism (APE). METHODS: According to risk stratification, 69 patients with APE admitted into the emergency department within 24 hours after onset were divided into the following 3 groups: high-risk group, moderate-risk group and low-risk group. H-FABP- and cardiac troponin I (cTNI)-positive rates of all groups were analyzed and compared, and the correlation between major adverse events (death, endotracheal intubation and cardiopulmonary resuscitation) and the cardiac markers (heart rate, arterial partial pressure of oxygen, right ventricular dimension, pulmonary arterial pressure, etc...
December 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27912923/predictors-of-30-day-mortality-in-patients-admitted-to-emergency-departments-for-acute-heart-failure
#11
Matthieu Marchetti, Antoine Benedetti, Olivier Mimoz, Jean-Yves Lardeur, Jérémy Guenezan, Nicolas Marjanovic
OBJECTIVES: Acute heart failure (AHF) is a leading cause of admission in emergency departments (ED). It is associated with significant in-hospital mortality, suggesting that there is room for improvement of care. Our aims were to investigate clinical patterns, biological characteristics and determinants of 30-day mortality. METHODS: We conducted a single site, retrospective review of adult patients (≥18years) admitted to ED for AHF over a 12-month period. Data collected included demographics, clinical, biological and outcomes data...
November 22, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27903616/immediate-rule-out-of-acute-myocardial-infarction-using-electrocardiogram-and-baseline-high-sensitivity-troponin-i
#12
Johannes Tobias Neumann, Nils Arne Sörensen, Francisco Ojeda, Tjark Schwemer, Jonas Lehmacher, Saskia Gönner, Nikolas Jarsetz, Till Keller, Sarina Schaefer, Thomas Renné, Ulf Landmesser, Peter Clemmensen, Nataliya Makarova, Renate B Schnabel, Tanja Zeller, Mahir Karakas, John W Pickering, Martin Than, William Parsonage, Jaimi Greenslade, Louise Cullen, Dirk Westermann, Stefan Blankenberg
AIMS: Serial measurements of high-sensitivity troponin are used to rule out acute myocardial infarction (AMI) with an assay specific cutoff at the 99th percentile. Here, we evaluated the performance of a single admission troponin with a lower cutoff combined with a low risk electrocardiogram (ECG) to rule out AMI. METHODS: Troponin I measured with a high-sensitivity assay (hs-TnI) was determined at admission in 1040 patients presenting with suspected AMI (BACC study)...
January 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/27903080/inter-pregnancy-interval-and-adverse-outcomes-evidence-for-an-additional-risk-in-health-disparate-populations
#13
Shyama Appareddy, Jason Pryor, Beth Bailey
OBJECTIVE: Short interpregnancy interval (IPI), <18 months between pregnancies, is a potential cause of adverse delivery and birth outcomes, and may be a particular issue among those with other risks. Our goal was to examine IPI and delivery/infant complications in Tennessee. METHODS: Birth certificate/vital records data included 101,912 women with a previous delivery. IPI groups (<6, 6-12, 12-18, 18-60 months) were compared on outcomes. RESULTS: Thirty-nine percent of the deliveries had IPI <18 months, 9% were <6 months, rates 11% and 27% higher than nationally...
December 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27889914/predictors-of-long-term-mortality-in-older-patients-hospitalized-for-acutely-decompensated-heart-failure-clinical-relevance-of-natriuretic-peptides
#14
Andrea Passantino, Piero Guida, Rocco Lagioia, Enrico Ammirati, Fabrizio Oliva, Maria Frigerio, Domenico Scrutinio
BACKGROUND: Acute heart failure is a common cause of hospitalization among older patients. Optimized risk stratification might improve the outcome for this subgroup of patients. Natriuretic peptides have been used in the diagnosis of heart failure and in evaluating the prognosis of patients hospitalized for heart failure. However, their utility in the elderly is still controversial. OBJECTIVE: To evaluate long-term survival and prognostic factors for elderly patients hospitalized for acutely decompensated heart failure and evaluate the prognostic utility of NT-proBNP...
November 27, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27884923/clinical-metrics-in-emergency-medicine-the-shock-index-and-the-probability-of-hospital-admission-and-inpatient-mortality
#15
Kamna S Balhara, Yu-Hsiang Hsieh, Bachar Hamade, Ryan Circh, Gabor D Kelen, Jamil D Bayram
STUDY OBJECTIVES: The shock index (SI), defined as the ratio of HR to systolic BP, has been studied as an alternative prognostic tool to traditional vital signs in specific disease states and subgroups of patients. However, literature regarding its utility in the general ED population is lacking. Our main objective was to determine the probability of admission and inpatient mortality based on the first measured SI at initial presentation in the general adult ED population in our tertiary care centre...
November 24, 2016: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/27881180/polypharmacy-and-adverse-outcomes-after-hip-fracture-surgery
#16
Maria Härstedt, Cecilia Rogmark, Richard Sutton, Olle Melander, Artur Fedorowski
BACKGROUND: We aimed to explore the effects of polypharmacy and specific drug classes on readmissions and mortality after hip surgery. METHODS: We analyzed data on 272 consecutive hip fracture patients (72.1% females; age 82 ± 9 years) who underwent acute hip replacement. We collected detailed data on the pharmacological treatment upon admission and discharge. Patients were followed up over a period of 6 months after discharge using the Swedish National Hospital Discharge Register and the Swedish National Cause of Death Register...
November 24, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27875713/prognostic-value-of-degree-and-types-of-anaemia-on-clinical-outcomes-for-hospitalised-older-patients
#17
Emma Riva, Riccardo Colombo, Guido Moreo, Sara Mandelli, Carlotta Franchi, Luca Pasina, Mauro Tettamanti, Ugo Lucca, Pier Mannuccio Mannucci, Alessandro Nobili
STUDY OBJECTIVE: This study investigated in a large sample of in-patients the impact of mild-moderate-severe anaemia on clinical outcomes such as in-hospital mortality, re-admission, and death within three months after discharge. METHODS: A prospective multicentre observational study, involving older people admitted to 87 internal medicine and geriatric wards, was done in Italy between 2010 and 2012. The main clinical/laboratory data were obtained on admission and discharge...
March 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27863295/the-effect-of-early-psychological-symptom-severity-on-long-term-functional-recovery-a-secondary-analysis-of-data-from-a-cohort-study-of-minor-injury-patients
#18
Sara F Jacoby, Justine Shults, Therese S Richmond
BACKGROUND: The mental health consequences of injuries can interfere with recovery to pre-injury levels of function and long term wellbeing. OBJECTIVES: The purpose of this study was to explore the relationship between psychological symptoms after minor injury and long-term functional recovery and disability. DESIGN: This exploratory study uses secondary data derived from a longitudinal cohort study of psychological outcomes after minor injury...
January 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/27862659/triglyceride-to-high-density-lipoprotein-cholesterol-ratio-predicts-worse-outcomes-after-acute-ischaemic-stroke
#19
Q-W Deng, H Wang, C-Z Sun, F-L Xing, H-Q Zhang, L Zuo, Z-T Gu, F-L Yan
BACKGROUND AND PURPOSE: The effect of the triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) ratio (TG/HDL-C) on clinical outcomes of acute ischaemic stroke (AIS) patients is unclear. This study sought to determine whether the TG/HDL-C ratio in AIS patients is associated with worse outcomes at 3 months. METHODS: Acute ischaemic stroke patients who were admitted from 2011 to 2014 were enrolled in this study. TG, total cholesterol (TC), HDL-C and low-density lipoprotein cholesterol (LDL-C) were collected on admission...
February 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27861823/predictors-of-12-months-relapse-after-withdrawal-treatment-in-hospitalized-patients-with-chronic-migraine-associated-with-medication-overuse-a-longitudinal-observational-study
#20
Alberto Raggi, Ambra M Giovannetti, Matilde Leonardi, Emanuela Sansone, Silvia Schiavolin, Marcella Curone, Licia Grazzi, Susanna Usai, Domenico D'Amico
BACKGROUND: Studies addressing relapse rates conflate relapse into chronic migraine (CM) and medication overuse (MO), and the consequent need to repeat withdrawal. We aim to identify 12-months predictors of relapse into CM (based on headaches frequency) separately from occurrence of another structured withdrawal. METHODS: Hospitalized patients with CM-MO under withdrawal were enrolled. Candidate predictors included demographic, disability, quality of life, depression scores, general self-efficacy, social support, headaches frequency and intensity, class of overused medications, history of withdrawal treatment in the three years prior to enrollment, attendance to emergency room (ER) between enrollment and follow-up, nonattendance to outpatient neurological examinations...
January 2017: Headache
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