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https://www.readbyqxmd.com/read/29330731/human-plant-exposures-reported-to-a-regional-southwestern-poison-control-center-over-8%C3%A2-years
#1
Ben Enfield, Daniel E Brooks, Sharyn Welch, Maureen Roland, Jane Klemens, Kim Greenlief, Rachel Olson, Richard D Gerkin
BACKGROUND: There is little published data about human plant exposures reported to US poison control centers (PCCs). METHODS: A retrospective chart review of all reported plant exposures to a single regional PCC between January 1, 2003 and December 31, 2010 was done to understand better the characteristics of plant exposure cases. Specific generic plant codes were used to identify cases. Recorded variables included patient demographics, plant involved, exposure variables, symptoms, management site, treatments, and outcome...
January 12, 2018: Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology
https://www.readbyqxmd.com/read/29260012/time-courses-of-plasma-il-6-and-hmgb-1-reflect-initial-severity-of-clinical-presentation-but-do-not-predict-poor-neurologic-outcome-following-subarachnoid-hemorrhage
#2
Heikki Kiiski, Jaakko Långsjö, Jyrki Tenhunen, Marika Ala-Peijari, Heini Huhtala, Mari Hämäläinen, Eeva Moilanen, Juha Öhman, Jukka Peltola
Objective: Patients with aneurysmal subarachnoid hemorrhage (aSAH) experience high mortality and morbidity. Neuroinflammation causes brain damage expansion after aSAH. Due to the complexity of the inflammatory response multiple biomarkers are needed to evaluate its' progression. We studied inflammatory process after aSAH by measuring two inflammatory biomarkers, interleukin-6 (IL-6) and high-mobility group box 1 (HMGB1) at simultaneous time-points after aSAH. Methods: In this prospective population-based study, IL-6 and HMGB1 were measured in aSAH patients (n = 47) for up to five days...
March 2017: ENeurologicalSci
https://www.readbyqxmd.com/read/29258745/recovery-from-childhood-community-acquired-pneumonia-in-a-developing-country-prognostic-value-of-serum-procalcitonin
#3
Taiane S Fonseca, Ângela G Vasconcellos, Dominique Gendrel, Olli Ruuskanen, Cristiana M Nascimento-Carvalho
BACKGROUND: Childhood community-acquired pneumonia is a common and potentially life-threatening illness in developing countries. We assessed the prognostic value of serum procalcitonin level upon admission on clinical response to antibiotic treatment. METHODS: Out of 89 patients, the median (IQR) age was 19(12-29) months and 60% were boys. Viral (49.5%), typical bacterial (38%) and atypical bacterial (12.5%) infections as well as probable pneumococcal infections (26%) were diagnosed...
December 16, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29251667/procalcitonin-and-presepsin-as-prognostic-markers-after-out-of-hospital-cardiac-arrest
#4
Pirkka T Pekkarinen, Giuseppe Ristagno, Erika Wilkman, Serge Masson, Roberto Latini, Johanna Laurikkala, Stepani Bendel, Tero Ala-Kokko, Tero Varpula, Jukka Vaahersalo, Sari Karlsson, Marjaana Tiainen, Monica M Mion, Mario Plebani, Ville Pettilä, Markus B Skrifvars
BACKGROUND: Patients resuscitated from cardiac arrest commonly develop an inflammatory response called post-cardiac arrest syndrome that clinically resembles septic shock.Procalcitonin and presepsin are associated with inflammation. We hypothesized that these biomarkers reflect the severity of post-cardiac arrest syndrome and predict short-term haemodynamical instability and long-term neurological outcome after cardiac arrest. METHODS: As a subcohort analysis of a prospective, observational, multi-centre study "FINNRESUSCI", we obtained plasma from 277 intensive care unit (ICU) patients treated following out-of-hospital cardiac arrest (OHCA)...
December 14, 2017: Shock
https://www.readbyqxmd.com/read/29249008/secondary-imaging-for-suspected-appendicitis-after-equivocal-ultrasound-time-to-disposition-of-mri-compared-to-ct
#5
James F Martin, David J Mathison, Paul C Mullan, Hansel J Otero
PURPOSE: The purpose of this study was to compare MRI to CT as a secondary imaging modality for children age 5 years and older with suspected appendicitis after an equivocal abdominal ultrasound in terms of (1) the time to ED disposition decision, (2) surgery consultation rate, and (3) imaging test accuracy. METHODS: We retrospectively studied children with suspected appendicitis and equivocal ultrasound results who underwent MR or CT as secondary imaging in a pediatric emergency department over two-consecutive 9-month periods...
December 16, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/29179592/elevated-plasma-procalcitonin-level-predicts-poor-prognosis-of-st-elevation-myocardial-infarction-in-asian-elderly
#6
Junru Dai, Bangbo Xia, Xiaomiao Wu
Previous studies have focused on relationship between plasma procalcitonin level and myocardial infarction risk, but this relationship in Asian elderly has not been investigated. The aim of this study was to reveal the association of peripheral procalcitonin concentration (both immediate and average levels) with myocardial infarction prognosis in Asian elderly. A total of 400 ST-elevation myocardial infarction patients, 400 unstable angina patients and 400 controls were included. Plasma levels of high-sensitivity C-reactive protein and procalcitonin were measured using commercially available kits...
November 27, 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29177378/-progression-of-chronic-renal-disease-in-a-reference-hospital-of-social-security-of-peru-2012-2015
#7
Jessica Bravo-Zúñiga, Ricardo Chávez-Gómez, Jungmei Gálvez-Inga, Mirko Villavicencio-Carranza, José Espejo-Sotelo, Manuel Riveros-Aguilar
OBJECTIVES.: To describe the characteristics of the population with chronic kidney disease (CKD) stage 3 and 4, to determine the factors associated with CKD progression and admission to renal replacement therapy (RRT), as well as renal survival. MATERIALS AND METHODS.: Longitudinal retrospective study of patients referred between January 2012 and December 2015 to the Renal Health Unit of the Hospital Nacional Edgardo Rebagliati Martins (HNERM), who were evaluated and followed by a multidisciplinary team...
April 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29175384/neuron-specific-enolase-and-s-100b-in-prolonged-targeted-temperature-management-after-cardiac-arrest-a-randomised-study
#8
Christophe Henri Valdemar Duez, Anders Morten Grejs, Anni Nørgaard Jeppesen, Anne Dilani Schrøder, Eldar Søreide, Jørgen Feldbæk Nielsen, Hans Kirkegaard
BACKGROUND: We aimed to investigate the impact of prolonged targeted temperature management (TTM) in cardiac arrest patients on release of serum levels of NSE and S-100b and their prognostic performances. METHODS: This is a substudy of the Targeted Temperature Management for 24 vs 48hours trial. NSE and S-100b levels were analysed retrospectively in serum samples collected upon admission, at 24, 48, and 72hours after reaching the target temperature of 33 ±1°C...
November 21, 2017: Resuscitation
https://www.readbyqxmd.com/read/29170303/6%C3%A2-prognostic-value-of-the-glasgow-admission-prediction-score-hospital-length-of-stay-mortality-and-hospital-readmission
#9
Dominic Jones, Allan Cameron, Suzanne Mason, Colin O'Keeffe, David Lowe
INTRODUCTION: As patient numbers presenting to emergency departments (ED) increase, with their myriad of comorbidities, early hospital admission prediction and demand modelling are crucial both in the ED and beyond. The Glasgow admission prediction score (GAPS) (figure 1)1 has already been shown to be accurate in predicting hospital admission from the ED at the point of triage.2 As demand on EDs increase, data driven models such as GAPS will become increasingly important for predicting patient course...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29165723/the-impact-of-hyperosmolarity-on-long-term-outcome-in-patients-presenting-with-severe-hyperglycemic-crisis-a-population-based-study
#10
Ivan Kruljac, Miroslav Ćaćić, Petra Ćaćić, Lora Stanka Kirigin Biloš, Davor Kust, Božidar Perić, Maja Filipović-Grčić, Gorana Mirošević, Vedran Ostojić, Mario Štefanović, Milan Vrkljan
Aims We compared characteristics of patients with hyperglycemic hyperosmolar state (HHS) and patients with severe hyperglycemia without the signs of hyperosmolarity and ketoacidosis; analyzed long-term all-cause mortality and potential prognostic factors. Methods The studied population included 261 749 adults. HHS was diagnosed in patients with plasma glucose >33.0 mmol/L, ketonuria <1+, and serum osmolarity >320 mmol/L. Patients with plasma glucose >33.0 mmol/L, ketonuria <1+ and serum osmolarity <320 mmol/L were considered as controls (nHHS)...
November 17, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29158121/systemic-cytokines-and-chemokines-on-admission-of-children-hospitalized-with-community-acquired-pneumonia
#11
Ângela G Vasconcellos, Jorge Clarêncio, Daniela Andrade, Maria-Regina A Cardoso, Aldina Barral, Cristiana M Nascimento-Carvalho
Community-acquired pneumonia (CAP) is the main cause of death in children under-5 years worldwide and Streptococcus pneumoniae is the most common bacterial agent. However, it is difficult to identify pneumococcal infection among children with CAP. We aimed to assess association between any cytokine/chemokine and pneumococcal infection in childhood CAP. Furthermore, we evaluated the diagnostic value of cytokine/chemokine for pneumococcal infection. This prospective study was conducted at an Emergency Room, in Salvador, Brazil...
November 17, 2017: Cytokine
https://www.readbyqxmd.com/read/29150390/pulmonary-embolism-rule-out-criteria-perc-rule-in-european-patients-with-low-implicit-clinical-probability-percepic-a-multicentre-prospective-observational-study
#12
Andrea Penaloza, Caroline Soulié, Thomas Moumneh, Quentin Delmez, Alexandre Ghuysen, Dominique El Kouri, Christian Brice, Nicolas S Marjanovic, Jacques Bouget, Fares Moustafa, Albert Trinh-Duc, Catherine Le Gall, Lionel Imsaad, Jean-Marie Chrétien, Béatrice Gable, Philippe Girard, Olivier Sanchez, Jeannot Schmidt, Grégoire Le Gal, Guy Meyer, Nicolas Delvau, Pierre-Marie Roy
BACKGROUND: The ability of the pulmonary embolism rule-out criteria (PERC) to exclude pulmonary embolism without further testing remains debated outside the USA, especially in the population with suspected pulmonary embolism who have a high prevalence of the condition. Our main objective was to prospectively assess the predictive value of negative PERC to rule out pulmonary embolism among European patients with low implicit clinical probability. METHODS: We did a multicentre, prospective, observational study in 12 emergency departments in France and Belgium...
November 14, 2017: Lancet Haematology
https://www.readbyqxmd.com/read/29128152/intravenous-thrombolytic-therapy-for-acute-anterior-ischemic-stroke-experience-at-the-french-military-teaching-hospital-in-toulon-from-2003-to-2014
#13
P Sahuc-Rodrigues, E Sagui, D Wybrecht, J-B Veyrières, S Gazzola, A Dagain, J Valance, P Alla, A Faivre
INTRODUCTION: Intravenous thrombolysis with rt-PA is the key treatment for acute ischemic stroke (IS), and has largely been developed at the Military Teaching Hospital in Toulon since 2003. This report is of the results of our practices compared with those in the literature, as well as our attempts to identify factors predictive of a favorable outcome after thrombolysis. METHODS: All patients treated with rt-PA for IS in the carotid territory between 2003 and 2014 were prospectively included...
November 8, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/29105897/chronic-intensive-care-related-pain-exploratory-analysis-on-predictors-and-influence-on-health-related-quality-of-life
#14
P Baumbach, T Götz, A Günther, T Weiss, W Meissner
BACKGROUND: There is growing evidence for the development of chronic pain after intensive care. Nonetheless, there is only limited knowledge about factors leading to chronic intensive care-related pain (CIRP). Thus, the primary objective was the identification of predictors of CIRP. Moreover, we aimed to assess the impact of CIRP on patients' health-related quality of Life (HRQOL). METHODS: Comprehensive information on patients' pain before ICU admission and present pain was collected longitudinally by means of the German Pain Questionnaire 6 and 12 months after ICU discharge (ICUDC )...
November 5, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29102693/children-with-chronic-pain-response-trajectories-following-intensive-pain-rehabilitation-treatment
#15
Laura E Simons, Christine B Sieberg, Caitlin Conroy, Edin T Randall, Julie Shulman, David Borsook, Charles Berde, Navil F Sethna, Deirdre E Logan
Intensive pain rehabilitation programs for children with chronic pain are effective for many patients. However, characteristics associated with treatment response have not been well documented. Here we report trajectories of pain and functional impairment in patients with chronic pain up to one year after intensive pain rehabilitation and examine baseline factors associated with treatment response. Patients (n=253) with chronic pain and functional disability were assessed at 5 time points (admission, discharge, 1-month, 4-month, and 12-month follow-up)...
November 1, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29050948/detection-of-malaria-parasites-after-treatment-in-travelers-a-12-months-longitudinal-study-and-statistical-modelling-analysis
#16
Manijeh Vafa Homann, S Noushin Emami, Victor Yman, Christine Stenström, Klara Sondén, Hanna Ramström, Mattias Karlsson, Muhammad Asghar, Anna Färnert
The rapid clearance of malaria parasite DNA from circulation has widely been accepted as a fact without being systemically investigated. We assessed the persistence of parasite DNA in travelers treated for Plasmodium falciparum malaria in a malaria-free area. Venous blood was collected at the time of admission and prospectively up to one year. DNA and RNA were extracted and analyzed using species-specific and gametocyte-specific real-time PCR as well as merozoite surface protein 2 (msp2)-PCR. In 31 successfully treated individuals, asexual parasites were seen by microscopy until two days after treatment, whereas parasite DNA was detected by msp2- and species-specific PCR up to days 31 and 42, respectively...
November 2017: EBioMedicine
https://www.readbyqxmd.com/read/29047023/heparin-binding-protein-hbp-improves-prediction-of-sepsis-related-acute-kidney-injury
#17
Jonas Tverring, Suvi T Vaara, Jane Fisher, Meri Poukkanen, Ville Pettilä, Adam Linder
BACKGROUND: Sepsis-related acute kidney injury (AKI) accounts for major morbidity and mortality among the critically ill. Heparin-binding protein (HBP) is a promising biomarker in predicting development and prognosis of severe sepsis and septic shock that has recently been proposed to be involved in the pathophysiology of AKI. The objective of this study was to investigate the added predictive value of measuring plasma HBP on admission to the intensive care unit (ICU) regarding the development of septic AKI...
October 18, 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/29030902/the-prognostic-significance-of-early-and-late-right-precordial-lead-v4-r-st-segment-elevation-in-patients-with-acute-anterior-myocardial-infarction
#18
Muhammed Keskin, Ahmet Okan Uzun, Edibe Betül Börklü, Mert İlker Hayıroğlu, Ceyhan Türkkan, Ahmet İlker Tekkeşin, Ömer Kozan
BACKGROUND: The predictive significance of ST-segment elevation (STE) in lead V4 R in patients with anterior ST-segment elevation myocardial infarction (STEMI) has not been well-understood. In this study, we evaluated the prognostic value of early and late STE in lead V4 R in patients with anterior STEMI. METHODS: A total 451 patients with anterior STEMI who treated with primary percutaneous coronary intervention (PPCI) were prospectively enrolled in this study...
October 14, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29016242/early-predictors-of-abscess-development-after-perforated-pediatric-appendicitis
#19
Catherine M Dickinson, Nathan A Coppersmith, Francois I Luks
BACKGROUND: Approximately one-third of children with appendicitis present with advanced disease or perforation. Whereas this increases the risk for post-operative complications and re-admission, it is not yet possible to predict early on who will develop an abdominal abscess. We sought to identify specific risk factors for this complication, in an attempt to streamline post-operative care. PATIENTS AND METHODS: We reviewed the records of all cases of perforated appendicitis over a 12-month period at a tertiary children's hospital...
October 10, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28993841/extent-of-jugular-venous-distension-and-lower-extremity-edema-are-the-best-tools-from-history-and-physical-examination-to-identify-heart-failure-exacerbation
#20
H R Omar, M Guglin
INTRODUCTION: We aimed to identify the best tools from history and physical examination that predict severity of heart failure (HF) exacerbation among patients with an ejection fraction (EF) ≤ 30%. METHODS: Patients enrolled in the ESCAPE trial were divided into tertiles according to the combined value of pulmonary capillary wedge pressure (PCWP) and right atrial pressure (RAP) which we used as a marker of volume loading of both pulmonary and systemic compartments...
October 9, 2017: Herz
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