keyword
https://read.qxmd.com/read/30489337/role-of-immunotherapy-in-stage-iii-nonsmall-cell-lung-cancer
#1
REVIEW
Anna Wrona
PURPOSE OF REVIEW: Despite aggressive treatment based on definitive chemoradiotherapy, 5-year overall survival in unresectable stage III nonsmall cell lung cancer remains poor (15-20%). The novel immunotherapy based on immune checkpoint inhibitors (ICIs) presents as the therapeutic 'Holly Grail' in lung cancer treatment. RECENT FINDINGS: Preclinical models provide evidence of immunotherapy-radiotherapy (IM-RT) synergy. The exposure to ionizing radiation turns tumor in an in-situ vaccine, primes the innate immune system, increases immunotherapy efficacy by overcoming the immunosuppressive microenvironment of immune-resistant tumors and promotes a systemic, out-of-field antitumor T-cell-mediated response called abscopal effect...
January 2019: Current Opinion in Oncology
https://read.qxmd.com/read/27679095/total-laparoscopic-hysterectomy-tlh-a-holly-grail-or-a-harbinger-of-trouble
#2
K Datsun, M Allam, K ElSapagh
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
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