keyword
https://read.qxmd.com/read/37726698/a-dietary-pattern-of-frequent-plant-based-foods-intake-reduced-the-associated-risks-for-atopic-dermatitis-exacerbation-insights-from-the-singapore-malaysia-cross-sectional-genetics-epidemiology-cohort
#21
JOURNAL ARTICLE
Jun Jie Lim, Kavita Reginald, Yee-How Say, Mei Hui Liu, Fook Tim Chew
BACKGROUND: The prevalence of atopic dermatitis (AD) has been increasing in recent years, especially in Asia. There is growing evidence to suggest the importance of dietary patterns in the development and management of AD. Here, we seek to understand how certain dietary patterns in a Singapore/Malaysia population are associated with various risks of AD development and exacerbation. METHODS: A standardized questionnaire following the International Study of Asthma and Allergies in Childhood (ISAAC) guidelines was investigator-administered to a clinically and epidemiology well-defined allergic cohort of 13,561 young Chinese adults aged 19-22...
September 19, 2023: BMC Public Health
https://read.qxmd.com/read/37638038/-limosilactobacillus-reuteri-in-immunomodulation-molecular-mechanisms-and-potential-applications
#22
REVIEW
Zichen Luo, Ailing Chen, Anni Xie, Xueying Liu, Shanyu Jiang, Renqiang Yu
Frequent use of hormones and drugs may be associated with side-effects. Recent studies have shown that probiotics have effects on the prevention and treatment of immune-related diseases. Limosilactobacillus reuteri ( L. reuteri ) had regulatory effects on intestinal microbiota, host epithelial cells, immune cells, cytokines, antibodies (Ab), toll-like receptors (TLRs), tryptophan (Try) metabolism, antioxidant enzymes, and expression of related genes, and exhibits antibacterial and anti-inflammatory effects, leading to alleviation of disease symptoms...
2023: Frontiers in Immunology
https://read.qxmd.com/read/37622257/maternal-fish-oil-and-or-probiotics-intervention-allergic-diseases-in-children-up-to-two-years-old
#23
RANDOMIZED CONTROLLED TRIAL
Miisa Komulainen, Lotta Saros, Tero Vahlberg, Merja Nermes, Tuomas Jartti, Kirsi Laitinen
BACKGROUND: As n-3 long-chain polyunsaturated fatty acids and probiotics possess immunomodulatory properties, theoretically they could lower the risk of allergic diseases. But their effects remain controversial. We aimed to study the effects of fish oil and probiotics separately or in combination from early pregnancy onwards to lower the risk of allergic diseases in the infants. METHODS: In this double-blind trial, women (n = 439) in early pregnancies were randomized into four intervention groups: fish oil + placebo, probiotics + placebo, fish oil + probiotics, and placebo + placebo...
August 2023: Pediatric Allergy and Immunology
https://read.qxmd.com/read/37531845/limosilactobacillus-fermentum-modulates-the-gut-airway-axis-by-improving-the-immune-response-through-foxp3-activation-on-combined-allergic-rhinitis-and-asthma-syndrome-caras
#24
JOURNAL ARTICLE
Raquel F P Cavalcanti, Francisco A A F Gadelha, Laércia K D Paiva Ferreira, Larissa A M Paiva Ferreira, José V Chaves Júnior, Rayanne S de Araújo Batista, Taynara B L Melo, Fábio S de Souza, Adriano F Alves, Leônia Maria Batista, Marcia R Piuvezam
Combined allergic rhinitis and asthma syndrome (CARAS) is an allergic airway inflammatory disorder orchestrated by the type 2 immune response. The close gut-lung relationship has been described, however, the effect of gut-modulating agents such as probiotics in allergic airway disorder is unclear. Thus, the goal of this study was to evaluate theLimosilactobacillus fermentumsupplementation in animals with CARAS. Therefore, BALB/c mice were ovalbumin (OVA) -sensitized and -challenged after being supplemented withL...
July 26, 2023: Immunobiology
https://read.qxmd.com/read/37515878/lactobacillus-rhamnosus-76-alleviates-airway-inflammation-in-ovalbumin-allergic-mice-and-improves-mucus-secretion-by-down-regulating-stat6-spdef-pathway
#25
JOURNAL ARTICLE
Yangfan Hou, Shuping Zheng, Fan Zou, Dan Wang, Hongju Da, Yong Zhou, Xinping Fan, Jianghao Liu, Hongyan Zhao, Jin He, Hongxin Li, Xiuzhen Sun, Yun Liu
Previous studies have reported a correlation between the dysregulation of intestinal microbiota and the occurrence of asthma. This study aimed to investigate the effect of probiotic Lactobacillus rhamnosus 76 (LR76) on ovalbumin (OVA)-allergic mice and the mechanism of LR76 affecting mucus secretion in asthma. OVA-allergic mice were supplemented with LR76, and 16HBE cells induced by interleukin-13 (IL-13) were treated with LR76 supernatant (LR76-s) to observe the effect of LR76. In OVA-sensitized mice, LR76 alleviated the inflammatory cell infiltration in lung tissue and reduced the inflammatory cell counts of BALF...
July 17, 2023: Immunobiology
https://read.qxmd.com/read/37496406/the-effectiveness-of-probiotics-in-treating-food-and-cow-s-milk-allergies-among-pediatric-age-group-a-meta-analysis-of-randomized-controlled-trials
#26
JOURNAL ARTICLE
Hua Feng, Yongning Wu
The global prevalence of allergies is on the rise. Food allergies are of special concern among children under 5 years of age, leading to morbidity and mortality. Though the standard management is avoidance, probiotics are being used widely to prevent and treat food allergies. We aimed to determine the effect of probiotics as a therapeutic option for controlling food and cow's milk allergy among children under 5 years of age. A systematic search of electronic medical literature databases was conducted. We included all eligible randomized controlled trials available from inception until May 2021...
April 30, 2023: Iranian Journal of Allergy, Asthma, and Immunology
https://read.qxmd.com/read/37464466/low-dose-perinatal-supplementation-with-enterococcus-faecalis-increases-concentrations-of-short-chain-fatty-acids-in-the-offspring-but-does-not-protect-them-against-asthma
#27
JOURNAL ARTICLE
Jeanne L Arntz, Moumen M Alhasan, Swarali Datye, Fariz G Kalahleh, Yahia Almousa, Gabriela Barrientos, Andreas Schwiertz, Melanie L Conrad
Childhood allergic asthma is associated with a dysbiotic gut microbiome in early life, and maternal perinatal treatment with probiotics is a potential way alter the infant microbiome, which may improve asthma outcomes. This study used a mouse model to examine the effect of maternal supplementation with the probiotic Enterococcus faecalis on fecal short-chain fatty acid (SCFA) concentrations and asthma risk in offspring. Pregnant/lactating mice were treated daily, from gestation day 6 to postnatal day 21, with an oral suspension of 10 6, 10 7 or 10 8 colony-forming units of a live preparation of the probiotic E...
July 19, 2023: International Immunology
https://read.qxmd.com/read/37384109/clinical-trial-of-a-probiotic-and-herbal-supplement-for-lung-health
#28
JOURNAL ARTICLE
Nancy M Wenger, Luhua Qiao, Teodora Nicola, Zoha Nizami, Isaac Martin, Brian A Halloran, Kosuke Tanaka, Michael Evans, Xin Xu, Timothy G Dinan, Charles Kakilla, Gillian DunnGalvin, Namasivayam Ambalavanan, Kent A Willis, Amit Gaggar, Charitharth Vivek Lal
INTRODUCTION: Dysbiosis of the gut microbiome may augment lung disease via the gut-lung axis. Proteobacteria may contribute to tissue proteolysis followed by neutrophil recruitment, lung tissue injury, and perpetuation of chronic inflammation. To study the effects of probiotics across the gut-lung axis, we sought to determine if a Lactobacillus probiotic and herbal blend was safe and well-tolerated in healthy volunteers and asthmatic patients. METHODS: We conducted a 1-month randomized, open-label clinical trial in Cork, Ireland with healthy and asthmatic patients who took the blend twice a day...
2023: Frontiers in Nutrition
https://read.qxmd.com/read/37371713/the-role-of-the-microbiome-in-the-pathogenesis-and-treatment-of-asthma
#29
REVIEW
Katarzyna Logoń, Gabriela Świrkosz, Monika Nowak, Martyna Wrześniewska, Aleksandra Szczygieł, Krzysztof Gomułka
The role of the microbiome in the pathogenesis and treatment of asthma is significant. The purpose of this article is to show the interplay between asthma and the microbiome, and main areas that require further research are also highlighted. The literature search was conducted using the PubMed database. After a screening process of studies published before May 2023, a total of 128 articles were selected in our paper. The pre-treatment bronchial microbiome in asthmatic patients plays a role in their responsiveness to treatment...
June 2, 2023: Biomedicines
https://read.qxmd.com/read/37346906/cost-effectiveness-of-therapeutic-infant-formulas-for-cow-s-milk-protein-allergy-management
#30
JOURNAL ARTICLE
Narissara Suratannon, Panote Prapansilp, Athitaya Srinarongsook, Pornthep Tanpowpong, Pantipa Chatchatee, Krit Pongpirul
Cow's milk protein allergy (CMPA) is children's most common food allergy. Therapeutic infant formulas for CMPA lead to symptom-free and potentially benefit early tolerance induction and reducing the allergic march in non-breastfed babies. This study assessed the cost-effectiveness of CMPA management with different therapeutic infant formulas in Thailand, which may reflect situations in developing countries throughout Asia. An analytic decision model was developed to simulate the occurrence of eczema, urticaria, asthma, rhinoconjunctivitis, or being symptom-free in infants with CMPA over 36 months...
2023: Frontiers in Nutrition
https://read.qxmd.com/read/37340968/lung-microbiota-its-relationship-to-respiratory-system-diseases-and-approaches-for-lung-targeted-probiotic-bacteria-delivery
#31
REVIEW
Nilufer Yuksel, Busra Gelmez, Ayca Yildiz-Pekoz
Microorganisms that make up the local microbiota (such as Lactobacillus sp. and Bifidobacterium sp.) play a crucial role in the modulation of diseases and health states by taking place not only in the gut but also in many parts of our body. There is also interference between the gut and the lung via the gut-lung axis. The relationship between respiratory diseases and lung microbiota, which become more of an issue of particular importance in recent years, shows that probiotics play an essential role in maintaining the balance of microorganisms in the respiratory tract...
June 21, 2023: Molecular Pharmaceutics
https://read.qxmd.com/read/37316240/-development-and-prevention-of-childhood-asthma
#32
JOURNAL ARTICLE
Manabu Miyamoto
No abstract text is available yet for this article.
2023: Arerugī, [Allergy]
https://read.qxmd.com/read/37314373/updates-in-the-diagnosis-and-practical-management-of-allergic-rhinitis
#33
REVIEW
Chiara Trincianti, Maria Angela Tosca, Giorgio Ciprandi
INTRODUCTION: Allergic rhinitis (AR) is a widespread disease that can be associated with other conditions, including conjunctivitis, rhinosinusitis, asthma, food allergy, and atopic dermatitis. Diagnosis is based on the history and documentation of sensitization, such as the production of allergen-specific IgE, preferably using molecular diagnostics. Treatments are based on patient education, non-pharmacological and pharmacological remedies, allergen-specific immunotherapy (AIT), and surgery...
2023: Expert Review of Clinical Pharmacology
https://read.qxmd.com/read/37277225/strains-of-faecalibacterium-prausnitzii-and-its-extracts-reduce-blood-glucose-levels-percent-hba1c-and-improve-glucose-tolerance-without-causing-hypoglycemic-side-effects-in-diabetic-and-prediabetic-mice
#34
JOURNAL ARTICLE
John Kallassy, Emily Gagnon, Dawn Rosenberg, Lawrence K Silbart, Simon A McManus
INTRODUCTION: The commensal bacterium Faecalibacterium prausnitzii is a prominent member of the microbiome of animals and humans, and it plays an important role in several physiological processes. Numerous studies have correlated the reduction of F. prausnitzii abundance with many disease states, including irritable bowel syndrome, Crohn's disease, obesity, asthma, major depressive disorder, and metabolic diseases in humans. Studies have also correlated F. prausnitzii with diseases in humans involved in altered glucose metabolism, including diabetes...
June 2023: BMJ Open Diabetes Research & Care
https://read.qxmd.com/read/37094604/probiotics-in-asthma-management-fiction-or-truth
#35
EDITORIAL
Giorgio Ciprandi, Maria Angela Tosca, Lorenzo Drago
No abstract text is available yet for this article.
May 2023: Expert Review of Clinical Immunology
https://read.qxmd.com/read/37075794/therapeutic-and-preventive-effect-of-orally-administered-prebiotics-on-atopic-dermatitis-in-a-mouse-model
#36
JOURNAL ARTICLE
Minje Kang, Ji-Hye Jung, Ji-Young Kim, Seok-Ho Hong, Young Her
PURPOSE: Recently, interest is increasing in using prebiotics, which are nutrient ingredients of live microorganism that improve the intestinal environments by promoting the growth of beneficial gut microflora. Although numerous studies have demonstrated the beneficial effects of probiotics on atopic dermatitis (AD) development, few have examined preventive and therapeutic effects of prebiotics on the onset and progression of AD. METHODS: In this study, we investigated therapeutic and preventive effect of prebiotics, including β-glucan and inulin, using an oxazolone (OX)-induced AD-like mouse model...
January 17, 2023: Allergy, Asthma & Immunology Research
https://read.qxmd.com/read/37073761/treating-asthma-patients-with-probiotics-a-systematic-review-and-meta-analysis
#37
JOURNAL ARTICLE
Qiwei Xie, Jiatian Yuan, Yaoweng Wang
OBJECTIVE: To evaluate the role of probiotics in the treatment of asthma patients by meta-analysis. METHODS: PubMed, Embase, The Cochrane Library, Web of Science, and other databases were searched by computer, and the relevant literature on the treatment of asthma by probiotics that met the inclusion criteria was screened by manual retrieval. Meta-analysis was performed using Revman 5.4 software and the combined effect was evaluated by odds ratio (OR) or mean difference (MD) and 95 % confidence interval (CI)...
April 11, 2023: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://read.qxmd.com/read/37041761/study-on-intestinal-flora-and-asthma-knowledge-graph-analysis-based-on-citespace-2001-2021
#38
REVIEW
Hang Zheng, Huan Dai, Xiumei Yan, Qiangwei Xiang
Asthma is a common chronic inflammatory disease of the airway. Intestinal flora, a significant risk factor for asthma, has become a widespread concern in the pathogenesis of asthma. To review the literature related to intestinal flora in asthma, summarize research direction, and report trends, this study used CiteSpace to perform bibliometric statistics and analysis on the research papers of intestinal flora and asthma collected in the Web of science core collection from 2001 to 2021. Eventually, a total of 613 articles were included...
2023: Journal of Asthma and Allergy
https://read.qxmd.com/read/37002629/immunosuppressive-effects-of-two-probiotics-lactobacillus-paracasei-dsm-13434-and-lactobacillus-plantarum-dsm-15312-on-cd4-t-cells-of-multiple-sclerosis-patients
#39
JOURNAL ARTICLE
Khadijeh Chakamian, Behrouz Robat-Jazi, Abdorreza Naser Moghadasi, Fatemeh Mansouri, Masoumeh Nodehi, Elahe Motevaseli, Maryam Izad, Saeed Yekaninejad, Mahdieh Shirzad, Kiana Bidad, Mona Oraei, Bita Ansaripour, Ali Akbar Saboor-Yaraghi
T cells play an important role in the development and progression of multiple sclerosis (MS), an autoimmune disease of the central nervous system. In the present study, the immunomodulatory impacts of two Lactobacillus strains, L paracasei DSM 13434 and L plantarum DSM 15312, on the frequency and cytokine production of CD4+ T cells in MS patients were explored. Thirty MS patients were enrolled in this study. The CD4+ T cells were isolated, cultured, and exposed to the media containing cell-free supernatants of L plantarum (group1), L paracasei (group 2), the mixture group of cell-free supernatants of both probiotics (group 3), and vehicle (control) group (group 4)...
February 20, 2023: Iranian Journal of Allergy, Asthma, and Immunology
https://read.qxmd.com/read/36967171/enrichment-of-formula-in-probiotics-or-prebiotics-and-risk-of-infection-and-allergic-diseases-up-to-age-5-5-years-in-the-nationwide-etude-longitudinale-fran%C3%A3-aise-depuis-l-enfance-elfe-cohort
#40
JOURNAL ARTICLE
Moufidath Adjibade, Camille Davisse-Paturet, Amandine Divaret-Chauveau, Karine Adel-Patient, Chantal Raherison, Marie-Noëlle Dufourg, Sandrine Lioret, Marie-Aline Charles, Blandine de Lauzon-Guillain
BACKGROUND: An increasing number of infant and follow-on formulas are enriched with probiotics and/or prebiotics; however, evidence for health effects of such enrichment in early childhood remains inconclusive. OBJECTIVES: The present study aimed to assess whether the consumption of formula enriched with probiotics or prebiotics was associated with the risk of infection and allergic diseases in early childhood. METHODS: Analyses involved data for 8389 formula-fed children from the Etude Longitudinale Française depuis l'Enfance (ELFE) cohort...
April 2022: Journal of Nutrition
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