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prevalence gastroesophageal reflux disease pediatric

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https://www.readbyqxmd.com/read/27868292/patterns-of-reflux-in-gastroesophageal-reflux-disease-in-pediatric-population-of-new-south-wales
#1
Sarath Kumar Narayanan, Ralph Clinton Cohen, Jonathan Saul Karpelowsky
This study is to determine the association of ambulatory pH monitoring (24hr pH) with symptoms of gastroesophageal reflux and its other investigations. The clinical and epidemiological profiles of subjects referred for reflux disorders are also studied. Symptoms or group of symptoms, profiles and prior investigations of 1259 consecutive pediatric subjects (with 1332 24hr pH studies performed) referred for evaluation of reflux disorders between 1988 and 2012 were retrospectively studied. Chi-square or fisher exact test was used for hypothesis testing, student t-test for the comparison of means and the Wilcoxon rank-sum test for comparing medians of continuous variables...
November 21, 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/27457769/prevalence-of-overlap-syndromes-and-symptoms-in-pediatric-functional-dyspepsia
#2
Craig A Friesen, John M Rosen, Jennifer V Schurman
BACKGROUND: The purpose was to evaluate the overlap frequency of irritable bowel syndrome (IBS), gastroesophageal reflux disease (GERD), and overactive bladder syndrome (OBS), as well as other gastrointestinal and systemic symptoms, in functional dyspepsia (FD). Additionally, we sought to determine whether adult Rome III FD subtypes were uniquely related to overlap syndromes or symptoms. METHODS: The study was a retrospective review of 100 consecutive pediatric patients, age 8-17 years, diagnosed with FD...
2016: BMC Gastroenterology
https://www.readbyqxmd.com/read/27274496/prevalence-and-characteristics-of-gastroesophageal-reflux-in-children-with-otitis-media-in-isfahan-iran
#3
Seyed Hamidreza Abtahi, Azadeh Kazerooni, Nezamodin Brejis, Zahra Abdeyazdan, Hossein Saneian
BACKGROUND: Otitis media (OM) is the most common cause of childhood hearing loss and reason to visit the pediatrician. Furthermore, gastroesophageal reflux (GER) has been associated with a variety of upper aerodigestive tract symptoms or diseases, such as sinusitis, laryngitis, and otits. The objective of the present study was to determine the frequency of GER in children, aged 3 months to 7 years, with OM. MATERIALS AND METHODS: This retrospective case-control study was conducted on 50 children with OM and 50 healthy children...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27138806/current-status-of-surgical-management-of-gastroesophageal-reflux-in-children
#4
Derek S Wakeman, Nicole A Wilson, Brad W Warner
PURPOSE OF REVIEW: Surgical therapy for gastroesophageal reflux disease (GERD) is controversial with considerable debate ranging from the indications for antireflux surgery to surgical technique. This article will attempt to clarify these issues with the most up-to-date information available on the prevalence, pathophysiology, diagnosis, and surgical treatment of GERD in children. Although laparoscopic Nissen fundoplication (LNF) has become the most popular operation performed for pathologic reflux, its superiority over both open surgery and other types of fundoplication is not well established...
June 2016: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/27068927/gastroesophageal-reflux-disease-in-children-with-interstitial-lung-disease
#5
M A Dziekiewicz, K Karolewska-Bochenek, Ł Dembiński, A Gawronska, K Krenke, J Lange, M Banasiuk, E Kuchar, M Kulus, P Albrecht, A Banaszkiewicz
Gastroesophageal reflux disease is common in adult patients with interstitial lung disease. However, no data currently exist regarding the prevalence and characteristics of the disease in pediatric patients with interstitial lung disease. The aim of the present study was to prospectively assess the incidence of gastroesophageal reflux disease and characterize its features in children with interstitial lung disease. Gastroesophageal reflux disease was established based on 24 h pH-impedance monitoring (MII-pH)...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27020622/signs-and-symptoms-associated-with-digestive-tract-development
#6
Mauro Batista de Morais
OBJECTIVE: To analyze the development and prevalence of gastrointestinal signs and symptoms associated with the development of the digestive tract, and to assess the measures aimed to reduce their negative impacts. SOURCE OF DATA: Considering the scope and comprehensiveness of the subject, a systematic review of the literature was not carried out. The Medline database was used to identify references that would allow the analysis of the study topics. SYNTHESIS OF RESULTS: Infants frequently show several gastrointestinal signs and symptoms...
May 2016: Jornal de Pediatria
https://www.readbyqxmd.com/read/26600973/eosinophilic-esophagitis-from-pathophysiology-to-treatment
#7
REVIEW
Alessandra D'Alessandro, Dario Esposito, Marcella Pesce, Rosario Cuomo, Giovanni Domenico De Palma, Giovanni Sarnelli
Eosinophilic esophagitis (EoE) is a chronic immune disease, characterized by a dense eosinophilic infiltrate in the esophagus, leading to bolus impaction and reflux-like symptoms. Traditionally considered a pediatric disease, the number of adult patients with EoE is continuously increasing, with a relatively higher incidence in western countries. Dysphagia and food impaction represent the main symptoms complained by patients, but gastroesophageal reflux-like symptoms may also be present. Esophageal biopsies are mandatory for the diagnosis of EoE, though clinical manifestations and proton pump inhibitors responsiveness must be taken into consideration...
November 15, 2015: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/26227470/is-mri-necessary-in-the-evaluation-of-pediatric-central-sleep-apnea
#8
Meghan Woughter, Amy M Perkins, Cristina M Baldassari
OBJECTIVES: (1) To determine the prevalence of central nervous system (CNS) pathology identified on head magnetic resonance imaging (MRI) scans in children with central sleep apnea (CSA); (2) to assess the yield of MRI in evaluation of CSA; and (3) to identify factors that predict CNS pathology in children with CSA. STUDY DESIGN: Case series with chart review. SETTING: Tertiary children's hospital. SUBJECTS AND METHODS: A chart review was conducted over 12 years...
December 2015: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/25605033/esophageal-atresia-and-transitional-care-step-1-a-systematic-review-and-meta-analysis-of-the-literature-to-define-the-prevalence-of-chronic-long-term-problems
#9
REVIEW
Martin J Connor, Laurie R Springford, Venediktos V Kapetanakis, Stefano Giuliani
BACKGROUND: Esophageal atresia (EA) is a rare congenital anomaly with high infantile survival rates. The aim of this study was to outline the prevalence of common long-term problems associated with EA repair in patients older than 10 years of age. DATA SOURCES: Original papers were identified by systematic searching of MEDLINE and EMBASE databases from January 1993 to July 2014. Fifteen articles (907 EA patients) met inclusion criteria. CONCLUSIONS: This is the first systematic review aiming to quantify the prevalence of the long-term problems associated with EA...
April 2015: American Journal of Surgery
https://www.readbyqxmd.com/read/25233350/impacts-of-endoscopic-gastroesophageal-flap-valve-grading-on-pediatric-gastroesophageal-reflux-disease
#10
Kai-Chi Chang, Jia-Feng Wu, Wei-Chung Hsu, Bor-Ru Lin, Huey-Ling Chen, Yen-Hsuan Ni
BACKGROUND: Gastroesophageal flap valve (GEFV) endoscopic grading is reported to be associated with gastroesophageal reflux disease (GERD) in adults; however its role in pediatric groups remains unknown. This study aimed to investigate the significance of GEFV grading and the associations to multichannel intraluminal impedance and pH monitoring (MII-pH) in children with GERD. METHODS: A total of 48 children with GERD symptoms who received esophagogastroduodenoscopy and MII-pH monitoring were enrolled...
2014: PloS One
https://www.readbyqxmd.com/read/25147680/the-prevalence-rate-of-helicobacter-pylori-infection-in-chronic-otitis-media-with-effusion-patients
#11
Nader Saki, Ali Reza Samarbaf Zadeh, Reza Sheikhpour Jonaky, Seyed Mahdi Noori, Gholam Abbas Kayedani, Soheila Nikakhlagh
BACKGROUND: Otitis media with effusion (OME) is a common disease in children. Viral or bacterial infections, allergy, adenoids, functional abnormalities of the Eustachian tube, and gastroesophageal reflux might have a possible role in the pathogenesis of OME. However, the exact pathogenesis of OME is still unsettled. OBJECTIVES: The purpose of this study was to compare Helicobacter pylori prevalence rates in the nasopharynx of pediatric patients with and without OME...
March 2014: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/25141229/impact-of-hiatal-hernia-on-pediatric-dyspeptic-symptoms
#12
Elena Scarpato, Maria D'Armiento, Massimo Martinelli, Valeria Mancusi, Severo Campione, Annalisa Alessandrella, Annamaria Staiano, Erasmo Miele
OBJECTIVES: Hiatal hernia (HH) affects from 10% to 50% of adult population. The correlation between HH, gastroesophageal reflux disease, dyspeptic symptoms, and esophagitis has long been known in adults. The primary objective of our prospective observational study was to estimate the prevalence of HH in children undergoing esophagogastroduodenoscopy (EGD), irrespective of their symptoms. METHODS: We prospectively enrolled 111 consecutive children (48 boys and 63 girls; mean age 94...
December 2014: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/25110424/pathophysiology-of-autism-spectrum-disorders-revisiting-gastrointestinal-involvement-and-immune-imbalance
#13
REVIEW
Mohtashem Samsam, Raheleh Ahangari, Saleh A Naser
Autism spectrum disorders (ASD) comprise a group of neurodevelopmental abnormalities that begin in early childhood and are characterized by impairment of social communication and behavioral problems including restricted interests and repetitive behaviors. Several genes have been implicated in the pathogenesis of ASD, most of them are involved in neuronal synaptogenesis. A number of environmental factors and associated conditions such as gastrointestinal (GI) abnormalities and immune imbalance have been linked to the pathophysiology of ASD...
August 7, 2014: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/24885375/an-italian-prospective-multicenter-survey-on-patients-suspected-of-having-non-celiac-gluten-sensitivity
#14
Umberto Volta, Maria Teresa Bardella, Antonino Calabrò, Riccardo Troncone, Gino Roberto Corazza
BACKGROUND: Non-celiac gluten sensitivity (NCGS) is still an undefined syndrome with several unsettled issues despite the increasing awareness of its existence. We carried out a prospective survey on NCGS in Italian centers for the diagnosis of gluten-related disorders, with the aim of defining the clinical picture of this new syndrome and to establish roughly its prevalence compared with celiac disease. METHODS: From November 2012 to October 2013, 38 Italian centers (27 adult gastroenterology, 5 internal medicine, 4 pediatrics, and 2 allergy) participated in this prospective survey...
2014: BMC Medicine
https://www.readbyqxmd.com/read/24753336/gastrointestinal-dysfunction-in-children-with-autism-spectrum-disorders
#15
Victor Kang, George C Wagner, Xue Ming
Gastrointestinal (GI) dysfunctions are frequently reported by parents of children with autism spectrum disorders (ASD) and have been recently recognized as a comorbid condition. However, the clinical significance of these GI dysfunctions remains to be delineated. This study describes the clinical characteristics, associated comorbid disorders, and endoscopic and colonoscopic evaluation of GI dysfunction in a cohort of 164 children with ASD evaluated at a pediatric neurology practice. Symptoms of GI dysfunction were prevalent: 49% of the children reported one or more chronic GI complaints, 22% exhibited diarrhea, 26% suffered from constipation...
August 2014: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/24742828/correlation-of-alox15-expression-with-eosinophilic-or-reflux-esophagitis-in-a-cohort-of-pediatric-patients-with-esophageal-eosinophilia
#16
Andres Matoso, Danisha Allen, Michael Herzlinger, Jason Ferreira, Sonja Chen, Shaolei Lu, Valeria Fabre, Renee Monahan, Dongfang Yang, Lelia Noble, Shamlal Mangray, Murray B Resnick
The differential diagnosis between eosinophilic esophagitis (EoE) and gastroesophageal reflux disease (GERD) is often challenging. We recently showed that the ALOX15 protein is expressed in 95% of esophageal biopsies from patients with a definitive diagnosis of EoE. Here we correlated ALOX15 expression with the clinical classification of EoE or GERD in a cohort of consecutive pediatric patients (n = 62) with at least 1 esophageal biopsy containing at least 15 eosinophils per high-power field (eos/HPF). The patients were categorized into the following groups: (1) at least 15 eos/HPF in the distal esophagus only (n = 24), (2) at least 15 eos/HPF in the proximal esophagus only (n = 5), and (3) at least 15 eos/HPF in the distal and proximal biopsies (n = 33)...
June 2014: Human Pathology
https://www.readbyqxmd.com/read/24051745/prevalence-of-eosinophilic-esophagitis-in-children-with-refractory-aerodigestive-symptoms
#17
COMPARATIVE STUDY
Courtney A Hill, Jyoti Ramakrishna, M Shannon Fracchia, Daniel Sternberg, Shilpa Ojha, Scott Infusino, Christopher J Hartnick
IMPORTANCE: Eosinophilic esophagitis (EoE) is an increasingly important diagnosis for children; it has a remarkable impact on their quality of life and can present with aerodigestive symptoms commonly evaluated by otolaryngologists. OBJECTIVES: To evaluate the prevalence of EoE in children presenting to a pediatric aerodigestive clinic, to describe their presentation, and to review the role of subsequent food allergy evaluation and treatment. DESIGN: Review of a prospective database...
September 2013: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/24006911/infants-under-3-months-old-with-cyanosis-at-the-emergency-room-could-it-be-gastroesophageal-reflux
#18
M Epifanio, J Eloi, A S Cassiano, D Pinheiro, J V Spolidoro
The aim of this study is to describe the prevalence of gastroesophageal reflux disease (GERD) in infants under 3 months old with a history of cyanotic episodes, who were examined at the emergency room of a university hospital. This descriptive study reviews reports of esophageal pH monitoring from a pediatric gastroenterology service over a period of 5 years. The following data were collected: age, sex, pediatric as well as other specialists' evaluations, and the esophageal pH monitoring reports. This study included 67 infants with a history of cyanotic episodes, with no primary cause determined by pediatrician and pediatric specialists' evaluations, who underwent esophageal pH monitoring...
May 2014: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/23974065/2013-update-on-celiac-disease-and-eosinophilic-esophagitis
#19
REVIEW
Rinaldo Pellicano, Claudio De Angelis, Davide Giuseppe Ribaldone, Sharmila Fagoonee, Marco Astegiano
Celiac disease is a chronic, immune-mediated disorder, characterized by small intestinal inflammation and villous atrophy after the ingestion of gluten by genetically susceptible individuals. Several extraintestinal manifestations have been associated to celiac disease. Eosinophilic esophagitis is a primary disorder of the esophagus characterized by upper gastrointestinal symptoms, absence of gastroesophageal reflux disease and more than 15 eosinophils per high-power field in biopsy specimens. Both celiac disease and eosinophilic esophagitis are caused by aberrant, but distinct, immune responses to ingested antigens and can be responsive to restricted food intake...
September 2013: Nutrients
https://www.readbyqxmd.com/read/23937680/association-of-problem-behavior-with-sleep-problems-and-gastroesophageal-reflux-symptoms
#20
Katsuyoshi Sakaguchi, Takakazu Yagi, Aya Maeda, Kunihiro Nagayama, Sawako Uehara, Yoko Saito-Sakoguchi, Kyoko Kanematsu, Shouichi Miyawaki
BACKGROUND: There are few large-scale epidemiologic studies examining the associations between sleep problems, gastroesophageal reflux disease (GERD) symptoms, lifestyle and food habits and problem behaviors (PB) in adolescents. The aim of this study was to evaluate the associations among these factors in Japanese adolescents. METHODS: A cross-sectional survey of 1840 junior high school students was carried out using questionnaires. The subjects were classified into PB or normal behavior (NB) groups using the Pediatric Symptom Checklist (PSC)...
February 2014: Pediatrics International: Official Journal of the Japan Pediatric Society
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