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https://www.readbyqxmd.com/read/27884123/the-spanish-version-of-the-childbirth-experience-questionnaire-ceq-e-reliability-and-validity-assessment
#1
F J Soriano-Vidal, A Oliver-Roig, J Cabrero-García, N Congost-Maestre, A Dencker, M Richart-Martínez
BACKGROUND: The Childbirth Experience Questionnaire (CEQ) was originally designed to study women's perceptions of labour and birth. The main objective of our study was to adapt the CEQ to the Spanish context and determine its psychometric properties. This would provide an opportunity to evaluate women's experiences in order to improve evidence in the Spanish context as recommended by national guidelines. METHODS: The CEQ was translated into Spanish using a standard forward and back translation method (CEQ-E)...
November 24, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27864355/disability-pension-due-to-common-mental-disorders-and-healthcare-use-before-and-after-policy-changes-a-nationwide-study
#2
S Rahman, E Mittendorfer-Rutz, K Alexanderson, J Jokinen, P Tinghög
BACKGROUND: Despite common mental disorders (CMDs) being a main reason for preterm exit from the labour market, there is limited knowledge regarding healthcare use around the time of being granted disability pension (DP) due to CMD. The aim was to study specialized healthcare use before and after being granted DP due to CMD and whether these trajectories differed before and after changes in DP granting criteria in Sweden in 2008. METHODS: Included individuals lived in Sweden, aged 19-64 years with incident DP due to CMD before (wave 1, 2005-06, n = 24 298) or after (wave 2, 2009-10, n = 4056) the changes in 2008...
November 17, 2016: European Journal of Public Health
https://www.readbyqxmd.com/read/27863606/use-of-complementary-and-alternative-medicine-in-pregnancy-and-its-impact-on-obstetric-outcome
#3
Juliana Yusof, Zaleha Abdullah Mahdy, Rushdan Mohd Noor
OBJECTIVE: To evaluate the prevalence of use of complementary and alternative medicine (CAM) in a Malaysian antenatal population and its impact on obstetric outcome. DESIGN: Cross sectional study. SETTING: Obstetric Unit, Hospital Sultanah Bahiyah, Alor Setar, Kedah. MATERIAL AND METHOD: Women attending antenatal clinic and Patient Admission Centre (PAC) above 30 weeks gestation were given structured questionnaires to fill...
November 2016: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/27836377/-prevention-of-spontaneous-preterm-birth-excluding-preterm-premature-rupture-of-membranes-guidelines-for-clinical-practice%C3%A2-%C3%A2-text-of-the-guidelines-short-text
#4
L Sentilhes, M-V Sénat, P-Y Ancel, E Azria, G Benoist, J Blanc, G Brabant, F Bretelle, S Brun, M Doret, C Ducroux-Schouwey, A Evrard, G Kayem, E Maisonneuve, L Marcellin, S Marret, N Mottet, S Paysant, D Riethmuller, P Rozenberg, T Schmitz, H Torchin, B Langer
OBJECTIVES: To determine the measures to prevent spontaneous preterm birth (excluding preterm premature rupture of membranes)and its consequences. MATERIALS AND METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: In France, premature birth concerns 60,000 neonates every year (7.4 %), half of them are delivered after spontaneous onset of labor...
November 8, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27821647/preclinical-evaluation-of-drugs-to-block-inflammation-driven-preterm-birth
#5
Demelza J Ireland, Elizabeth A Nathan, Shaofu Li, Adrian K Charles, Lisa F Stinson, Matthew W Kemp, John P Newnham, Jeffrey A Keelan
Intrauterine inflammation, the major cause of early preterm birth, can have microbial and sterile aetiologies. We assessed in a Transwell model the anti-inflammatory efficacies of five drugs on human extraplacental membranes delivered after preterm spontaneous labour (30-34 wk). Drugs [TPCA1 (IKKβ inhibitor), 5 z-7-oxozeaenol (OxZ, TAK1 inhibitor), inhibitor of NF-κB essential modulator binding domain (iNBD), SB239063 (p38 MAPK inhibitor) and N-acetyl cysteine (free radical scavenger free radicals)] were added after 12 h equilibration to the amniotic compartment...
November 7, 2016: Innate Immunity
https://www.readbyqxmd.com/read/27817049/overexpression-of-endogenous-anti-oxidants-with-selenium-supplementation-protects-trophoblast-cells-from-reactive-oxygen-species-induced-apoptosis-in-a-bcl-2-dependent-manner
#6
Alisha Khera, Jessica J Vanderlelie, Olivia Holland, Anthony V Perkins
The human placenta provides life support for the developing foetus, and a healthy placenta is a prerequisite to a healthy start to life. Placental tissue is subject to oxidative stress which can lead to pathological conditions of pregnancy such as preeclampsia, preterm labour and intrauterine growth restriction. Up-regulation of endogenous anti-oxidants may alleviate placental oxidative stress and provide a therapy for these complications of pregnancy. In this study, selenium supplementation, as inorganic sodium selenite (NaSel) or organic selenomethionine (SeMet), was used to increase the protein production and cellular activity of the important redox active proteins glutathione peroxidase (GPx) and thioredoxin reductase (Thx-Red)...
November 5, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27806709/benefits-and-harms-of-screening-for-and-treatment-of-asymptomatic-bacteriuria-in-pregnancy-a-systematic-review
#7
Konstanze Angelescu, Barbara Nussbaumer-Streit, Wiebke Sieben, Fülöp Scheibler, Gerald Gartlehner
BACKGROUND: Most European and North American clinical practice guidelines recommend screening for asymptomatic bacteriuria (ASB) as a routine pregnancy test. Antibiotic treatment of ASB in pregnant women is supposed to reduce maternal upper urinary tract infections (upper UTIs) and preterm labour. However, most studies supporting the treatment of ASB were conducted in the 1950s to 1980s. Because of subsequent changes in treatment options for ASB and UTI, the applicability of findings from these studies has come into question...
November 2, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27806664/complement-c5a-is-present-in-csf-of-human-newborns-and-is-elevated-in-association-with-preterm-birth
#8
Rozalia Pataky, A Forbes Howie, Guillermina Girardi, James P Boardman
Neuroinflammation contributes to developmental brain injury associated with preterm birth, but the mediators that drive it are incompletely understood. Previous studies have shown that complement C5a is present and injurious in the brains of fetal mice exposed to preterm labour. Here, we demonstrate that C5a is present in the cerebrospinal fluid of newborn human infants, and that levels are elevated in those born preterm. The difference is not explained by systemic infection. The role of complement activation in the neonatal brain and its role as a potential therapeutic target for preterm brain injury warrants further study...
November 2, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27783473/impact-of-azithromycin-on-pregnancy-prolongation-in-women-at-risk-of-preterm-labor-a-time-to-event-analysis
#9
Isabelle Goyer, Gabrielle Ferland, Ni Ruo, Caroline Morin, Marie-Sophie Brochet, Lucie Morin, Ema Ferreira
BACKGROUND: Since 2006, the empiric use of azithromycin in women at risk of premature birth has become prevalent in our institution without any evidence of its efficacy. Although antibiotics can prolong pregnancy in preterm prolonged rupture of membranes, no published data are available for women with intact membranes. OBJECTIVES: To describe the purpose of adding azithromycin to the usual treatments (cerclage, tocolysis, rest, etc.) to prolong pregnancy in women with intact membranes who are at risk of or already in preterm labour...
September 13, 2016: Journal of Population Therapeutics and Clinical Pharmacology
https://www.readbyqxmd.com/read/27780541/atf3-is-a-negative-regulator-of-inflammation-in-human-fetal-membranes
#10
Ratana Lim, Gillian Barker, Stella Liong, Caitlyn Nguyen-Ngo, Stephen Tong, Tu'uhevaha Kaitu'u-Lino, Martha Lappas
INTRODUCTION: Infection and inflammation stimulate pro-inflammatory cytokines, prostaglandins and matrix metalloproteinase (MMP)-9, which play a central role in myometrial contractions and rupture of fetal membranes. In human and mouse immune cells, activating transcription factor 3 (ATF3) is a negative regulator of inflammation. No studies have examined the role of ATF3 in human labour. METHODS: Primary amnion cells were used to determine the effect of interleukin (IL)-1β and the bacterial product fibroblast-stimulating lipopeptide (fsl-1) on ATF3 expression, and the effect of ATF3 siRNA on pro-labour mediators...
November 2016: Placenta
https://www.readbyqxmd.com/read/27769268/second-harmonic-generation-microscopy-reveals-collagen-fibres-are-more-organised-in-the-cervix-of-postmenopausal-women
#11
Brenda F Narice, Nicola H Green, Sheila MacNeil, Dilly Anumba
BACKGROUND: During labour, the cervix undergoes a series of changes to allow the passage of the fetoplacental unit. While this visible transformation is well-described, the underlying and causative microscopic changes, in which collagen plays a major role, are poorly understood and difficult to visualise. Recent studies in mice and humans have shown that Second Harmonic Generation (SHG) microscopy, a non-destructive imaging technique, can detect changes in the cervical collagen. However, the question of whether SHG can identify changes in the arrangement of cervical collagen at different physiological stages still needs addressing...
October 21, 2016: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/27764886/-female-preterm-monozygotic-twins-discordant-for-fetal-megacystis-due-to-cloacal-dysgenesis-after-conception-by-intracytoplasmatic-sperm-injection-case-report-and-review-of-literature
#12
M Schneider, I Schmeh, A Fruth, C Whybra-Trümpler, E Mildenberger
Monozygotic twins were previously regarded as "identical". By now an increasing number of case reports of monozygotic but discordant twins have been reported, and therefore discordance between monozygotic twins is being investigated intensively. We report a case of female preterm monozygotic twins who were discordant for fetal megacystis due to cloacal dysgenesis. Pregnancy was achieved after intracytoplasmatic sperm injection and transfer of 2 embryos. By the first trimester fetal megacystis with consecutive oligohydramnios and hypoplasia of the lungs was diagnosed...
October 2016: Zeitschrift Für Geburtshilfe und Neonatologie
https://www.readbyqxmd.com/read/27762324/maternal-and-live-birth-outcomes-of-pregnancies-following-assisted-reproductive-technology-a-retrospective-cohort-study
#13
Linling Zhu, Yu Zhang, Yifeng Liu, Runjv Zhang, Yiqing Wu, Yun Huang, Feng Liu, Meigen Li, Saijun Sun, Lanfeng Xing, Yimin Zhu, Yiyi Chen, Li Xu, Liangbi Zhou, Hefeng Huang, Dan Zhang
This study was carried out to explore associations between assisted reproductive technology (ART) and maternal and neonatal outcomes compared with similar outcomes following spontaneously conceived births. We conducted a retrospective cohort study of pregnancies conceived by ART (N = 2641) during 2006-2014 compared to naturally conceived pregnancies (N = 5282) after matching for maternal age and birth year. Pregnancy complications, perinatal complications and neonatal outcomes of enrolled subjects were investigated and analysed by multivariate logistic regression...
October 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27756710/is-ureaplasma-spp-the-leading-causative-agent-of-acute-chorioamnionitis-in-patients-with-preterm-birth
#14
Judith Kikhney, Dinah von Schöning, Ina Steding, Julia Schulze, Annett Petrich, Andreas Hiergeist, Udo Reischl, Annette Moter, Anke Thomas
OBJECTIVES: The aim of this study was to detect microorganisms in foetal membranes and placental tissue in preterm chorioamnionitis by combining FISH with broad range PCR. The combination of the two molecular techniques enables identification and localization of the microorganisms within the tissue, confirming their clinical relevance. METHODS: In a prospective cohort study, we compared 31 patients with preterm premature rupture of membranes or preterm labour and preterm delivery by caesarean section with a control group of 26 participants with elective caesarean section at term...
October 15, 2016: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/27750180/comparison-of-the-actim-partus-test-and-the-fetal-fibronectin-test-in-the-prediction-of-spontaneous-preterm-birth-in-symptomatic-women-undergoing-cervical-length-measurement
#15
Merel M C Bruijn, Jolande Y Vis, Femke F Wilms, Martijn A Oudijk, Anneke Kwee, Martina M Porath, Guid Oei, Hubertina C J Scheepers, Marc E A Spaanderman, Kitty W M Bloemenkamp, Monique C Haak, Antoinette C Bolte, Frank P H A Vandenbussche, Mallory D Woiski, Caroline J Bax, Jérôme M J Cornette, Johannes J Duvekot, Bas W A Nij Bijvank, Jim van Eyck, Maureen T M Franssen, Krystyna M Sollie, Joris A M van der Post, Patrick M M Bossuyt, Brent C Opmeer, M Kok, Ben W J Mol, Gert-Jan van Baaren
OBJECTIVE: To compare the accuracy of the Actim Partus test and fetal fibronectin (fFN) test in the prediction of spontaneous preterm delivery within seven days in symptomatic women undergoing cervical length measurement. STUDY DESIGN: We performed a post-hoc analysis on frozen samples of a nationwide cohort study in all 10 perinatal centres in the Netherlands. We selected samples from women with signs of preterm labour between 24 and 34 weeks of gestational age and a cervical length below 30mm...
November 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27748297/association-of-organochlorine-pesticides-with-the-mrna-expression-of-tumour-necrosis-factor-alpha-tnf-%C3%AE-cyclooxygenase-2-cox-2-genes-in-idiopathic-preterm-birth
#16
Vipin Tyagi, M D Mustafa, Tusha Sharma, B D Banerjee, Rafat S Ahmed, A K Tripathi, Kiran Guleria
BACKGROUND & OBJECTIVES: Preterm birth (PTB) is an important cause of prenatal death, neonatal morbidity and mortality and adult illness. Increased inflammation occurs in normal parturition, and inflammatory cytokines and oxidative stress are found to be higher in PTB cases. The present study was planned to investigate the association of organochlorine pesticides (OCPs) with mRNA expression of inflammatory pathway genes such as tumour necrosis factor-alpha (TNF-α) and cyclooxygenase-2 (COX-2) in preterm delivery (PTD) cases...
June 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27738479/optimal-weight-gain-during-pregnancy-in-japanese-women
#17
Shunji Suzuki
BACKGROUND: In order to examine the optimal weight gain during pregnancy in Japanese women, we analyzed the perinatal outcomes in Japanese women with the optimal range of weight gain during pregnancy according to the Japanese (the Japanese Ministry of Health, Labour and Welfare: JMHLW and the Japan Society for the Study of Obesity: JASSO) guidelines compared with those according to the USA (the Institute of Medicine: IOM) guideline. METHODS: We compared the obstetric outcomes in two groups of gestational weight gain within the optimal range based on the IOM and Japanese guidelines in women of pre-pregnancy body mass index (BMI) categories of underweight, normal, overweight and obese...
November 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27728996/social-stress-predicts-preterm-birth-in-twin-pregnancies
#18
David J Owen, Lorna Wood, Barbara Tomenson, Francis Creed, James P Neilson
OBJECTIVE: To investigate whether stress, anxiety and depression predict preterm birth in twin pregnancies. METHODS: A prospective cohort study with a convenience sample of women pregnant with dichorionic, diamniotic twins. They were interviewed at 24-28 weeks using the Life Events and Difficulties Schedule and the Hospital Anxiety and Depression Scale. Corticotrophin-releasing hormone, ACTH and cortisol levels were assessed at 28 weeks. The main outcome was premature delivery; there were 42 preterm and 73 term births...
October 11, 2016: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27680327/neonatal-and-obstetric-outcomes-in-diet-and-insulin-treated-women-with-gestational-diabetes-mellitus-a-retrospective-study
#19
Sarah H Koning, Klaas Hoogenberg, Kirsten A Scheuneman, Mick G Baas, Fleurisca J Korteweg, Krystyna M Sollie, Bertine J Schering, Aren J van Loon, Bruce H R Wolffenbuttel, Paul P van den Berg, Helen L Lutgers
BACKGROUND: To evaluate the neonatal and obstetric outcomes of pregnancies complicated by gestational diabetes mellitus (GDM). Screening and treatment - diet-only versus additional insulin therapy - were based on the 2010 national Dutch guidelines. METHODS: Retrospective study of the electronic medical files of 820 singleton GDM pregnancies treated between January 2011 and September 2014 in a university and non-university hospital. Pregnancy outcomes were compared between regular care treatment regimens -diet-only versus additional insulin therapy- and pregnancy outcomes of the Northern region of the Netherlands served as a reference population...
September 29, 2016: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/27671425/health-providers-perception-of-quality-of-care-for-neonates-in-health-facilities-in-a-municipality-in-southern-ghana
#20
Kokui Elikplim Pomevor, Augustine Adomah-Afari
Purpose The purpose of this paper is to assess available human resources for neonatal care and their skills, in order to explore health providers' perceptions of quality of neonatal care in health facilities in Ghana. Design/methodology/approach Data were gathered using qualitative interviews with health providers working in the maternity and paediatric wards and midwives; direct observation; and documentary review at a regional hospital, a municipal hospital and four health centres in a municipality in a region in Southern Ghana...
October 10, 2016: International Journal of Health Care Quality Assurance
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