Read by QxMD icon Read

Tension normal glaucoma

Achmed Pircher, Margherita Montali, Peter Wostyn, Joachim Pircher, Jatta Berberat, Luca Remonda, Hanspeter E Killer
PURPOSE: To investigate the cerebrospinal fluid (CSF) dynamics along the entire optic nerve (ON) in patients with normal-tension glaucoma (NTG). METHODS: Retrospective analysis of computed tomographic (CT) cisternographies in Caucasian patients with NTG. Fifty-six patients (99 of 112 eyes) fulfilled the diagnostic criteria of NTG and underwent CT-cisternography. Twelve subjects without NTG (24 eyes) served as controls. Contrast-loaded cerebrospinal fluid (CLCSF) density measurements in Hounsfield units (HU) were performed at four defined regions along the ON and in the basal cistern...
March 12, 2018: Acta Ophthalmologica
Florian S M Edlinger, Laura M Schrems-Hoesl, Christian Y Mardin, Robert Laemmer, Friedrich E Kruse, Wolfgang A Schrems
PURPOSE: Assessment of the diagnostic ability of segmented macular inner retinal layer thickness and peripapillary retinal nerve fiber layer (pRNFL) measured by spectral-domain optical coherence tomography (SD-OCT) in patients with normal-tension (NT) and high-tension (HT) perimetric and preperimetric glaucoma. METHODS: The 212 participants included 45 healthy subjects, 55 patients with ocular hypertension, 56 patients with preperimetric glaucoma, and 56 patients with perimetric glaucoma...
March 9, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
C Xiong, X Zhang
Migraine is a common primary headache disorder. The estimated annual prevalence rate of migraine in China is 9.3%. Migraine is typically involved with a series of ocular symptoms including glaucoma, visual performance tests relevant to glaucoma exhibited correlation between glaucoma and migraine. Even though migraine patients exhibit no glaucoma-related signs during intermissions of migraine attacks, the results of visual function tests (visual field, electrophysiology, ocular imaging) relevant to glaucoma still indicate abnormalities...
March 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
X Fan, L L Wu, G G Xiao, Z Z Ma, F Liu
Objective: To analyze potentials of frequency-doubling technology perimetry (FDP) for diagnosing open-angle glaucoma (OAG) in perimetrically normal eyes of OAG patients diagnosed with standard automated perimetry (SAP) and relating factors from abnormalities on FDP to visual field loss on SAP. Methods: A prospective cohort study. Sixty-eight eyes of 68 OAG patients visiting the ophthalmic clinic of Peking University Third Hospital during November 2003 and October 2007 [32 primary open-angle glaucoma patients and 36 normal tension glaucoma patients, 32 males and 36 females, with an average age of (59±13) years] with unilateral field loss detected by SAP (Octopus101 tG2 program) were examined with the FDP N-30 threshold program (Humphrey Instruments) at baseline...
March 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
B B Li, Y Cai, Y Z Pan, M Li, Y Fang, T Tian, X M Yan
Objective: To evaluate the association between corneal biomechanical parameters and visual field (VF) progression in normal tension glaucoma (NTG) using the Corvis-ST device, and to evaluate the ability of corneal biomechanical parameters to predict the VF progression. Methods: Corneal biomechanical parameters of newly diagnosed NTG patients were obtained using Corvis-ST in the baseline follow-up visit. The VF progression was defined as a 4-point increase in the Advanced Glaucoma Intervention Study (AGIS) score compared to the baseline in three consecutive follow-up visits (per 3-6 months)...
March 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Mihail Zemba, Tatiana Danilova, Liliana Pulbere, Alina-Cristina Stamate
Aim: To present diagnostic particularities, assessment of prognosis, and the need for treatment in a case of normal-tension glaucoma. Methods: - presentation of clinical changes and investigations supporting the diagnosis; - careful anamnesis that disclosed new elements, useful for the evaluation of the case. Results: after a two-year follow-up period, we can ascertain that the optic atrophy is non-progressive. Conclusions: the assessment of risk factors and a rigorous anamnesis were significant for the establishment of prognosis and need for treatment...
October 2017: Romanian Journal of Ophthalmology
Natalia Ivanovna Kurysheva, Tamara Yakovlevna Ryabova, Vitaliy Nikiforovich Shlapak
Relevance: Vascular factors may be involved in the development of both high tension glaucoma (HTG) and normal tension (NTG) glaucoma; however, they may be not exactly the same. Autonomic dysfunction characterized by heart rate variability (HRV) is one of the possible reasons of decrease in mean ocular perfusion pressure (MOPP). Purpose: To compare the shift of the HRV parameters in NTG and HTG patients after a cold provocation test (CPT). Methods: MOPP, 24-hour blood pressure and HRV were studied in 30 NTG, 30 HTG patients, and 28 healthy subjects...
March 2018: EPMA Journal
Arthur H Friedlander, Lindsay L Graves, Tina I Chang, K Karl Kawakami, Urie K Lee, Shannon C Grabich, Zhuang T Fang, Michelle R Zeidler, JoAnn A Giaconi
OBJECTIVE: Our objective was to determine primary open-angle glaucoma (POAG) prevalence among obstructive sleep apnea (OSA) patients because the perioperative environment risks further damaging the optic nerve. STUDY DESIGN: We analyzed a "convenience sample" referred by Sleep Medicine for oral appliances because of continuous positive airway pressure intolerance. We determined the aggregate prevalence of the 3 POAG subtypes-"classic" open-angle glaucoma (COAG), normal-tension glaucoma (NTG), and open-angle glaucoma suspect (OAGS)-among the index population and compared it with that of same hospital's general population...
January 31, 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Pushpa Raman, Nurull Bahya Suliman, Mimiwati Zahari, Michael Kook, Norlina Ramli
OBJECTIVE: To assess the relationship between baseline intraocular pressure (IOP), blood pressure (BP) and ocular perfusion pressure (OPP), and the 5-year visual field progression in normal-tension glaucoma (NTG) patients. DESIGN: Prospective, longitudinal study. METHODS: Sixty-five NTG patients who were followed up for 5 years are included in this study. All the enrolled patients underwent baseline 24-h IOP and BP monitoring via 2-hourly measurements in their habitual position and were followed up for over 5 years with reliable VF tests...
March 1, 2018: Eye
H E Killer, A Pircher
Normal tension glaucoma (NTG) is an exception in the "glaucoma family" where the major risk factor, increased intraocular pressure, is missing. If not increased intraocular pressure, then what other causes can then lead to glaucomatous optic disc change and visual field loss in NTG? Several possibilities will be discussed. Among them a higher sensitivity to normal pressure, vascular dysregulation, an abnormally high translaminar pressure gradient and a neurodegenerative process due to impaired cerebrospinal fluid dynamics in the optic nerve sheath compartment...
February 19, 2018: Eye
Rodolfo Mastropasqua, Luca Agnifili, Enrico Borrelli, Vincenzo Fasanella, Lorenza Brescia, Luca Di Antonio, Leonardo Mastropasqua
PURPOSE: To analyze the retinal radial peripapillary capillary (RPC) network in normal-tension glaucoma (NTG) and nonarteritic anterior ischemic optic neuropathy (NAION) eyes using optical coherence tomography angiography (OCTA). MATERIAL AND METHODS: Twenty-two patients with NTG, 22 patients with unilateral chronic NAION, and 23 age-matched controls were enrolled. Patients underwent OCTA to obtain en face angiograms of the peripapillary region. The main outcome measures were as follows: (1) the whole en face image perfusion density (WPD) and (2) the circumpapillary perfusion density (CPD)...
February 16, 2018: Current Eye Research
Ewa Kosior-Jarecka, Joanna Bartosińska, Urszula Łukasik, Dominika Wróbel-Dudzińska, Dorota Krasowska, Grażyna Chodorowska, Tomasz Żarnowski
The aim of the study was to evaluate the results of nailfold videocapillaroscopic examination in patients with normal-tension glaucoma (NTG) in comparison to age-matched individuals without glaucoma and young healthy volunteers and to assess the relation between the results of this examination with clinical status in NTG group. MATERIAL AND METHODS: The studied group consisted of 188 patients: 80 patients with NTG and 2 control groups (58 young healthy and 50 age-matched volunteers). The nailfold videocapillaroscopy (NVC) was performed in all participants...
February 16, 2018: Current Eye Research
Huan Xu, Ruyi Zhai, Yuan Zong, Xiangmei Kong, Chunhui Jiang, Xinghuai Sun, Yi He, Xiqi Li
PURPOSE: The aim of this study is to determine and compare the changes in the retinal vasculature in eyes with high-tension glaucoma (HTG) or normal-tension glaucoma (NTG). METHODS: The right eyes of 43 HTG subjects, 33 NTG subjects, and 51 age- and sex-matched normal subjects were included in this cross-sectional study. Signals were projected from the internal limiting membrane to retinal pigment epithelium. The retinal perfused vessel densities in the peripapillary and parafoveal regions were measured automatically with optic coherence tomography angiography and the split-spectrum amplitude-decorrelation angiography algorithm...
February 15, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Stephanie C Joachim
Glaucoma is one of the most common causes for blindness worldwide. Even if some risk factors for this disease are known, like increased intraocular pressure or increased age, its pathomechanism is still not fully understood. Multiple studies recently analyzed the role of a Helicobacter pylori infection in the glaucoma pathogenesis. Several studies showed a correlation, while others did not come to this conclusion. In summary, it is very likely that a Helicobacter pylori infection coincides with an increased risk for a primary open-angle or normal-tension glaucoma...
February 2018: Klinische Monatsblätter Für Augenheilkunde
Keiji Yoshikawa, Kazunori Santo, Hiroko Hizaki, Masayo Hashimoto
Purpose: To analyze factors related to long-term progression of visual field defects (VFD) in patients with normal tension glaucoma (NTG) under medical therapy. Patients and methods: Clinical data from 622 eyes of 311 primary open-angle glaucoma and NTG patients were collected from April 2006 to March 2016. Of these patients, those with normal intraocular pressure (IOP); glaucomatous VFD judged by Anderson's criteria; corrected visual acuity ≥0.7; receiving more than 6 years medical therapy; having undergone ≥10 visual field tests performed at 6-month intervals using a Humphrey field analyzer (Swedish Interactive Threshold Algorithms standard, C 24-2 program); and having reliability coefficients of visual field testing <33% and mean deviation (MD) more than -20 decibels in the initial visual field test were included in data analysis...
2018: Clinical Ophthalmology
Blake K Williamson, Nathan M Hawkey, Diane A Blake, Joshua W Frenkel, Kevin P McDaniel, Justin K Davis, Celine Satija, Alex Beazer, Suraj Dhungana, James Carlson, Susan McRitchie, Ramesh S Ayyala
Purpose: Glaucoma drainage device (GDD) implantation can lead to corneal decompensation. We evaluated changes over time in oxygen tension and in the metabolic environment of the aqueous humor after GDD implantation in the rabbit eye. Methods: Ahmed Glaucoma Valves were implanted in the left eyes of eight male New Zealand white rabbits. Right eyes were used as a control. Oxygen tension was measured immediately before surgery and at 1 and 2 months postoperation. Aqueous humor was collected from the surgical and control eyes at 1, 2, and 5 months postoperation...
February 2018: Translational Vision Science & Technology
Yoshiyuki Kita, Gábor Hollό, Akiko Murai, Ritsuko Kita, Akito Hirakata
PURPOSE: To determine the optical coherence tomography angiography (OCTA) characteristics of a case of optic disc melanocytoma (ODM) associated with glaucomatous visual field and retinal nerve fiber layer (RNFL) defects in normal tension glaucoma. METHODS: The left eye of a 37-year-old female patient followed for a stable ODM for 10 years was investigated with OCT, OCTA, fluorescein (FA), and indocyanine green (ICGA) angiography. The ODM was unchanged, but a previously unknown inferotemporal neuroretinal rim loss and inferotemporal and superotemporal wedge shape glaucomatous RNFL thinning were seen with corresponding glaucomatous visual field defects...
February 1, 2018: International Ophthalmology
Megumi Honjo, Nozomi Igarashi, Makoto Kurano, Yutaka Yatomi, Koji Igarashi, Kuniyuki Kano, Junken Aoki, Robert N Weinreb, Makoto Aihara
Purpose: To compare the levels of autotaxin (ATX), lysophosphatidic acid (LPA), and lysophosphatidylcholine (LPC) in the aqueous humor (AH) of healthy control subjects with those of patients with different subtypes of glaucoma, and also to investigate the relationship of the ATX-LPA pathway with IOP and subtype of glaucoma. Methods: This study included 164 eyes of 164 consecutive cases of cataract and glaucoma surgery (37 healthy, 31 normal tension glaucoma, 49 primary open angle glaucoma, 28 secondary open angle glaucoma, and 19 exfoliation glaucoma)...
February 1, 2018: Investigative Ophthalmology & Visual Science
Jessica N Cooke Bailey, Puya Gharahkhani, Jae H Kang, Mariusz Butkiewicz, David A Sullivan, Robert N Weinreb, Hugues Aschard, R Rand Allingham, Allison Ashley-Koch, Richard K Lee, Sayoko E Moroi, Murray H Brilliant, Gadi Wollstein, Joel S Schuman, John H Fingert, Donald L Budenz, Tony Realini, Terry Gaasterland, William K Scott, Kuldev Singh, Arthur J Sit, Robert P Igo, Yeunjoo E Song, Lisa Hark, Robert Ritch, Douglas J Rhee, Douglas Vollrath, Donald J Zack, Felipe Medeiros, Thasarat S Vajaranant, Daniel I Chasman, William G Christen, Margaret A Pericak-Vance, Yutao Liu, Peter Kraft, Julia E Richards, Bernard A Rosner, Michael A Hauser, Jamie E Craig, Kathryn P Burdon, Alex W Hewitt, David A Mackey, Jonathan L Haines, Stuart MacGregor, Janey L Wiggs, Louis R Pasquale
Purpose: Sex hormones may be associated with primary open-angle glaucoma (POAG), although the mechanisms are unclear. We previously observed that gene variants involved with estrogen metabolism were collectively associated with POAG in women but not men; here we assessed gene variants related to testosterone metabolism collectively and POAG risk. Methods: We used two datasets: one from the United States (3853 cases and 33,480 controls) and another from Australia (1155 cases and 1992 controls)...
February 1, 2018: Investigative Ophthalmology & Visual Science
Tae Hee Lee, Mi Sun Sung, Hwan Heo, Sang Woo Park
PURPOSE: The aim of this study was to investigate the association between tear film and meibomian gland parameters in patients with normal tension glaucoma (NTG), who underwent topical prostaglandin analog (PGA) monotherapy, and medication compliance. METHODS: Ocular surface disease index (OSDI), Schirmer's test, tear film break-up time (TBUT), keratoepitheliopathy (KEP) score with fluorescein, and meibomian gland parameters were assessed in 45 eyes of 45 patients with NTG (NTG group), who received topical PGA monotherapy for more than 1 year...
2018: PloS One
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"