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Zhiping Dun, Shugan Zhu, Hao Jiang
OBJECTIVE: Frame-based stereotactic surgical planning systems (SSPSs) have been used for deep brain stimulation and radioneurosurgery. Here, we evaluated the feasibility, safety and efficacy of using a SSPS to aid spontaneous intracerebral haematoma (ICH) treatment. METHODS: Patients with moderate spontaneous putamen haematomas were randomized into two groups: treatment (group A) and control (group B). In group B, the catheter for evacuating haematomas was inserted into a target point, located at the centre of the haematoma, using conventional frame-based stereotactics; urokinase thrombolysis was subsequently delivered through the catheter...
October 2013: Journal of International Medical Research
Sergio Moreno-Jiménez, Daniel San-Juan, José M Lárraga-Gutiérrez, Miguel A Celis, Mario A Alonso-Vanegas, David J Anschel
Callosotomy by radioneurosurgery induces slow and progressive axonal degeneration of white matter fibers, a key consequence of neuronal or axonal injury (radionecrosis). However, the acute effects are not apparent when using conventional MRI techniques. Diffusion tensor imaging (DTI) during the first week following radioneurosurgical callosotomy allowed evaluation of these microstructural changes. The present report details that the use of sequential DTI to evaluate axonal degeneration following radioneurosurgical callosotomy in a patient normalized with the data of six healthy subjects...
July 2012: Seizure: the Journal of the British Epilepsy Association
A Tournade, C Riquelme
The three treatment options for intracranial arteriovenous malformation are resection, endovascular embolization, and stereotactic radioneurosurgery, in rare cases, the malformation can be eradicated using only one of these options; most cases require a combination of the options, even all three. The most recent advances have been in interventional neuroradiology with the introduction of highdefinition 3D imaging and hyperselective intranidal endovascular embolization using rnicrocatheters and microguidewires, giving marked advantages in terms of rapidity, efficacy, and safety, Nidal devascularization is now much improved, as shown by the increased interval between embolization sessions, while high-field functional magnetic resonance imaging plays a valuable role in the preembolization work-up and postembolization follow-up...
September 2000: Dialogues in Clinical Neuroscience
Olivia Amanda García-Garduño, Miguel Angel Celis, José Manuel Lárraga-Gutiérrez, Sergio Moreno-Jiménez, Arnulfo Martínez-Dávalos, Mercedes Rodríguez-Villafuerte
Micro-multileaf collimator systems coupled to linear accelerators for radioneurosurgery treatments require a rigorous dosimetric characterization in order to be used in 3D conformal and intensity modulated stereotactic radiosurgery and radiotherapy applications. This characterization involves high precision measurements of leaf transmission, leakage and beam penumbra through the collimation system and requires the use of detectors with high spatial resolution, high sensitivity and practically no energy dependence...
June 23, 2008: Journal of Applied Clinical Medical Physics
Li-Gen Wang, Yan Guo, Xiang Zhang, Mei Shi, Shao-Jun Song, Li-Chun Wei
BACKGROUND & OBJECTIVE: The trans-sphenoid surgery was one of the main methods for the treatment of functional pituitary micro-adenoma for many years, while the development of radiosurgical techniques in recent years has given neurosurgeons new ways to treat functional pituitary micro-adenoma. This report aimed to ascertain the effectiveness of X-Knife stereotactic radioneurosurgery on pituitary micro-adenoma. METHODS: From June 1996 to June 2001, 143 cases of functional pituitary micro-adenoma were treated by X-Knife radiosurgery, in which 73 cases of secreting prolactin (PRL),54 cases of secreting growth hormone(GH), 13 cases of secreting adrenal corticotrophin hormone (ACTH), and 3 cases of secreting both PRL and GH...
May 2003: Ai Zheng, Aizheng, Chinese Journal of Cancer
N Massager
Integration of the metabolic data of PET in the dosimetry planning of radiosurgical treatment with the Gamma Knife, can optimize the definition of the target volume for infiltrating or ill-defined brain tumors. Our experience of twenty patients treated with this technique demonstrates the interest of this original approach that should improve the results of radiosurgical treatment of cerebral tumors.
2002: Bulletin et Mémoires de L'Académie Royale de Médecine de Belgique
C B Shields, Y T Guan, P R Almond, H D Garretson, R D Lindberg
Two available commercial units for radiosurgery are the modified linear accelerator (LINAC scalpel) and the gamma knife. Advantages of the LINAC scalpel over the gamma knife are its greater accuracy, the availability of a wide range of collimator sizes that allow for a more homogeneous field of radiation for large lesions, state-of-the-art computer software programs, and lower expense. Radiosurgery does not require an incision, is painless, and can be performed on an outpatient basis. It is ideally suited for the treatment of inaccessible, deep intracranial lesions that are radioresistant to conventional forms of radiotherapy, such as arteriovenous malformations, meningiomas, vestibular schwannomas, selected primary brain tumors, and cerebral metastases...
July 1993: Journal of the Kentucky Medical Association
J T Leith, S Cook, P Chougule, P Calabresi, L Wahlberg, C Lindquist, M Epstein
UNLABELLED: We have collected the in vitro x-ray radiation survival characteristics of 181 lines from 12 different classes of exponentially growing human tumor cells (sarcomas, lung cancers, colo-rectal cancers, medulloblastomas, melanoma, breast cancers, prostate cancers, renal cell cancers, grades III and IV brain tumors, ovarian, and head and neck cancers). This information was used to intercompare survival after single high doses of 20-40 Gy for each tumor line. Radiosensitivities could roughly be divided into two groups...
1994: Acta Neurochirurgica. Supplement
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