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Goiter in children

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https://www.readbyqxmd.com/read/28061776/poor-dietary-diversity-wealth-status-and-use-of-un-iodized-salt-are-associated-with-goiter-among-school-children-a-cross-sectional-study-in-ethiopia
#1
Zegeye Abebe, Ejigu Gebeye, Amare Tariku
BACKGROUND: Globally, more than two billion people are at risk of iodine deficiency disorders, 32% of which are school children. Iodine deficiency has been recognized as a severe public health concern in Ethiopia, however little is known about the problem. Therefore, this study aimed to assess the prevalence of goiter and associated factors among school children (6 to 12 years) in Dabat District, northwest Ethiopia. METHODS: A school-based cross-sectional study was conducted from February 21 to March 31, 2016...
January 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28003823/larger-thyroid-volume-and-adequate-iodine-nutrition-in-chinese-schoolchildren-local-normative-reference-values-compared-with-who-ign
#2
Zhe Mo, Xiaoming Lou, Guangming Mao, Zhifang Wang, Wenming Zhu, Zhijian Chen, Xiaofeng Wang
Objective. Thyroid volume measured by ultrasound to define goiter needs reliable local thyroid volume reference from iodine-sufficient populations. The aim of this study is to explore the reference interval for normal thyroid volume in schoolchildren aged 8-10 years from Zhejiang Province, China. Methods. A probability-proportionate-to-size sampling method was applied to select a representative sample of 1213 children aged 8-10 years in Zhejiang Province to detect the thyroid volume, salt iodine, and urine iodine...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28001012/iodine-deficiency-and-nutrition-in-scandinavia
#3
Sofia Manousou, Lisbeth Dahl, Betina H Thuesen, Lena Hulthén, Helena N Filipsson
Iodine nutrition is a result of geological conditions, iodine fortification and monitoring strategies within a country together with the dietary habits of the population. This review summarizes the basis for the current iodine situation in the Scandinavian countries in order to identify gaps in knowledge, determine necessary future steps, highlight landmarks in Scandinavian iodine research and consider ongoing studies in Scandinavian countries with high international impact. Historically, iodine deficiency disorders such as goiter were common in Norway and Sweden, but not in Denmark...
December 20, 2016: Minerva Medica
https://www.readbyqxmd.com/read/27942480/diagnostic-imaging-of-benign-and-malignant-neck-masses-in-children-a-pictorial-review
#4
REVIEW
Ruth Elizabeth Brown, Srikrishna Harave
Neck masses are frequently encountered in pediatric medicine, and can present a diagnostic dilemma for the clinicians involved. There are several means by which neck masses in children can be subdivided, for example by age at presentation, anatomical location including compartments and fascia of the neck, their classical appearance when imaged, or by etiology. When imaging children the clinicians must be mindful of radiation exposure and as such ultrasound (US) is often attempted first. Cross sectional imaging can be helpful for problem solving with CT being particularly useful for assessing the patient in more acute scenarios, for example when there is airway compromise...
October 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/27927635/associations-between-iodine-intake-thyroid-volume-and-goiter-rate-in-school-aged-chinese-children-from-areas-with-high-iodine-drinking-water-concentrations
#5
Wen Chen, Xiang Li, Yalan Wu, Jianchao Bian, Jun Shen, Wen Jiang, Long Tan, Xiaoming Wang, Wei Wang, Elizabeth N Pearce, Michael B Zimmermann, Alicia L Carriquiry, Wanqi Zhang
BACKGROUND: Excessive iodine intake may have adverse effects on the thyroid, particularly in children, but the safe upper iodine intake concentration in children is unclear. OBJECTIVE: We assessed the adverse effects of high iodine intake from iodine-rich drinking water on thyroid size in children by examining associations between thyroid volume (Tvol), total goiter rate (TGR), and iodine intake. DESIGN: In a multistage cross-sectional survey, we collected two 24-h urine samples on 2 nonconsecutive days and determined 24-h urinary iodine excretion, then calculated habitual daily iodine intake...
December 7, 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27867886/genotype-phenotype-correlations-of-dyshormonogenetic-goiter-in-children-and-adolescents-from-south-india
#6
Bangaraiah Gari Ramesh, Panchangam Ramakanth Bhargav, Bangaraiah Gari Rajesh, Nangedda Vimala Devi, Rajagopalan Vijayaraghavan, Bhongir Aparna Varma
BACKGROUND: Dyshormonogenetic goiter is one of the most common causes of hypothyroidism in children and adolescents in iodine nonendemic areas. The exact genotype-phenotypic correlations (GPCs) and risk categorization of hypothyroid phenotypes of dyshormonogenetic mutations are largely speculative. The genetic studies in pediatric dyshormonogenesis are very sparse from Indian sub-continent. In this context, we analyzed the implications of TPO, NIS, and DUOX2 gene mutations in hypothyroid children with dyshormonogenetic hypothyroidism (DH) from South India...
November 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27807474/iodine-deficiency-and-associated-factors-among-school-children-a-cross-sectional-study-in-ethiopia
#7
Sintayehu Hailu, Mamo Wubshet, Haile Woldie, Amare Tariku
BACKGROUND: Iodine deficiency remains a public health problem in the world. It is the leading cause of preventable mental retardation and brain damage worldwide. Though 12 million school age children are at risk of developing iodine deficiency, there is a scarcity of literature showing the magnitude of iodine deficiency in Ethiopia. Therefore, this study aimed to determine the prevalence and associated factors of iodine deficiency among school children in Robe District, southeast Ethiopia...
2016: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/27567653/iodine-deficiency-in-school-children-in-aligarh-district-india
#8
Ahmad Nadeem Aslami, Mohammed A Ansari, N Khalique, Umesh Kapil
We carried out this study to assess iodine deficiency disorders among school children of 6-12 years age group in Aligarh district of India. The prevalence of goiter was 5.2%. Median Urinary Iodine Excretion level was 150 ug/L; 22.5% of students had biochemical iodine deficiency. 50.4% households were consuming adequately iodized salt.
August 8, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27560630/current-status-of-iodine-deficiency-related-disorders-prophylaxis-in-slovakia-the-life-s-work-of-julian-podoba-remained-unfinished
#9
J Podoba, K Racova, H Urbankova, M Srbecky
OBJECTIVE: Prophylaxis of iodine deficiency-related disorders with iodized salt in Slovakia was introduced in 1951. This prophylactic measure yielded remarkably good results. Endemic goiter and endemic cretinism disappeared. Sufficient iodine intake, mainly in children and adolescents, was confirmed in several local and international studies carried out in the period 1991-95. Unfortunately, since seventies, there has been no institution which would have dealt with iodine prophylaxis in such an extent as this important measure of Slovak preventive medicine would require...
January 2016: Endocrine Regulations
https://www.readbyqxmd.com/read/27541030/ethical-and-surgical-dilemmas-in-patients-with-neglected-surgical-diseases-visiting-a-field-hospital-in-a-zone-of-recent-disaster
#10
Guy Lin, Tal Marom, David Dagan, Merin Ofer
OBJECT: The massive typhoon Haiyan (Yolanda) ripped across the central Philippines on November 8, 2013, and damaged infrastructure including hospitals. The Israeli Defense Forces field hospital was directed by the Philippine authorities to Bogo City in the northern part of the island of Cebu, to assist the damaged local hospital. Hundreds of patients with neglected diseases sought for medical treatment which was merely out of reach for them. Our ethical dilemmas were whether to intervene, when the treatment we could offer was not the best possible...
August 19, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27521067/2016-american-thyroid-association-guidelines-for-diagnosis-and-management-of-hyperthyroidism-and-other-causes-of-thyrotoxicosis
#11
Douglas S Ross, Henry B Burch, David S Cooper, M Carol Greenlee, Peter Laurberg, Ana Luiza Maia, Scott A Rivkees, Mary Samuels, Julie Ann Sosa, Marius N Stan, Martin A Walter
BACKGROUND: Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions and patient preference. This document describes evidence-based clinical guidelines for the management of thyrotoxicosis that would be useful to generalist and subspecialty physicians and others providing care for patients with this condition. METHODS: The American Thyroid Association (ATA) previously cosponsored guidelines for the management of thyrotoxicosis that were published in 2011...
October 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27489467/celiac-disease-in-children-and-adolescents-with-hashimoto-thyroiditis
#12
Hale Tuhan, Sakine Işık, Ayhan Abacı, Erdem Şimşek, Ahmet Anık, Özden Anal, Ece Böber
AIM: The aim of this study was to evaluate clinical and laboratory findings and determine the prevalence of celiac disease (CD) in children with Hashimoto thyroiditis (HT). MATERIAL AND METHODS: The data of a total of 80 patients with positive anti-thyroid antibodies who were aged between 6 and 17.9 years were retrospectively studied. Age, gender, complaints at the time of presentation, family history of thyroid disorders, clinical and laboratory findings were recorded...
June 2016: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/27462586/dilated-cardiomyopathy-with-graves-disease-in-a-young-child
#13
Yu Jung Choi, Jun Ho Jang, So Hyun Park, Jin-Hee Oh, Dae Kyun Koh
Graves disease (GD) can lead to complications such as cardiac arrhythmia and heart failure. Although dilated cardiomyopathy (DCMP) has been occasionally reported in adults with GD, it is rare in children. We present the case of a 32-month-old boy with DCMP due to GD. He presented with irritability, vomiting, and diarrhea. He also had a history of weight loss over the past few months. On physical examination, he had tachycardia without fever, a mild diffuse goiter, and hepatomegaly. The chest radiograph showed cardiomegaly with pulmonary edema, while the echocardiography revealed a dilated left ventricle with an ejection fraction (EF) of 28%...
June 2016: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/27395838/assessment-of-iodine-deficiency-in-school-children-in-aligarh-district-india
#14
Ahmad Nadeem Aslami, Mohammed A Ansari, N Khalique, Umesh Kapil
We carried out the study to assessw iodine deficiency disorders among school children of 6-12 years age group in Aligarh district of India. The prevalence of goiter was 5.2%. Modern Urinary Iodine Excretion level was 150 μg/l, 22.5% of students had biochemical iodine deficiency. 50.4% households were consuming adequately iodized salt.
June 1, 2016: Indian Pediatrics
https://www.readbyqxmd.com/read/27370068/iodine-status-and-prevalence-of-thyroid-disorders-after-introduction-of-mandatory-universal-salt-iodization-for-16-years-in-china-a-cross-sectional-study-in-10-cities
#15
Zhongyan Shan, Lulu Chen, Xiaolan Lian, Chao Liu, Bingyin Shi, Lixin Shi, Nanwei Tong, Shu Wang, Jianping Weng, Jiajun Zhao, Xiaochun Teng, Xiaohui Yu, Yaxin Lai, Weiwei Wang, Chenyan Li, Jinyuan Mao, Yongze Li, Chenling Fan, Weiping Teng
BACKGROUND: The goal of eliminating iodine deficiency worldwide was successfully achieved in China after the implementation of a mandatory universal salt iodization program for the last 16 years. Thus, China has been assessed as a country with more than adequate iodine levels. This survey aimed to investigate the current iodine status in China and the effects of an increased iodine intake on the spectrum and prevalence of thyroid disorders. METHODS: A total of 15,008 adult subjects from 10 cities in eastern and central China were investigated...
August 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27366719/a-community-based-case-control-study-to-investigate-the-role-of-iron-deficiency-in-the-persistence-of-goiter
#16
Rambha Pathak, Chintu Chaudhary, Rashmi Agarwalla, Zakirhusain Shaikh, R K D Goel, Bilkish Patvegar
OBJECTIVES: To find out the magnitude of iron deficiency anemia in the age group of 6-12 years and investigate the role of iron deficiency as a possible contributor to endemic goiter in school children in Ambala. MATERIALS AND METHODS: The present study was conducted as a subset of a cross-sectional study among 2700 children from 6 to 12 years of age to find out the prevalence of goiter. All the subjects who were found to be suffering from goiter in the cross-sectional study were enrolled in the case-control study as cases and were compared with age- and sex-matched controls (children without goiter) from the same cohort...
July 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27350707/prevalence-of-mental-retardation-in-urban-and-rural-populations-of-the-goiter-zone-in-northwest-india
#17
Shailja Sharma, Sunil Kumar Raina, Ashok Kumar Bhardwaj, Sanjeev Chaudhary, Vipasha Kashyap, Vishav Chander
BACKGROUND: The existence of an endemic goiter belt along the southern slopes of the Himalayas has been known for a long time. Prevalence of neonatal hypothyroidism is high and there has been little work on the prevalence of mental retardation in this part of India. OBJECTIVE: The study was conducted with the aim to know the prevalence of mental retardation in the urban and rural populations of Himachal Pradesh, India and to generate a hypothesis on the differential distribution (geographical) of mental retardation...
April 2016: Indian Journal of Public Health
https://www.readbyqxmd.com/read/27272160/lateralized-exanthem-mimicking-figurate-inflammatory-dermatosis-of-infancy-after-methimazole-therapy
#18
T Arrigo, P M Cutroneo, M Vaccaro, D Impollonia, V Squadrito, A Mecchio, C Salpietro, D Altavilla
We reported a case of an 11-year-old girl admitted to our hospital for goiter, tachycardia, sweating, and visible and palpable thyroid. Thyroid function tests revealed a low thyrotropin level (<0.004 mIU/L) and elevated free thyroxine level (3.4 ng/ dL) diagnosed with Graves' disease and treated with methimazole. This anti-thyroid drug is recommended as first-line treatment in children with Graves' disease because it produces minor adverse effects with respect to propylthiouracil. She developed a lateralized exanthem mimicking figurate inflammatory dermatosis of infancy after methimazole therapy...
December 2016: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/27266024/-assessment-of-the-iodine-status-in-the-population-in-western-kazakhstan-according-to-data-of-urinary-iodine-concentrations
#19
Kh I Kudabaeva, G K Koshmaganbetova, Ye Sh Bazargaliev, A M Baspakova
To evaluate iodine status in the population of Western Kazakhstan on the example oftheAktobe region according to data of urinary iodine concentrations. There were examined 2257 children aged from 7 to 12 years. Urinary iodine was carried out in 10% of schoolchildren by semiquantitative method under field conditions. According to the 30-cluster survey the prevalence of goiter in the region amounted to 42.71 ± 1.04%. The proportion of children with optimal urinary iodine concentrations is only 12.8%, more than 300 mcg/l--57...
2016: Gigiena i Sanitariia
https://www.readbyqxmd.com/read/27244854/iodine-deficiency-and-hypothyroidism-from-voluntary-diet-restrictions-in-the-us-case-reports
#20
Stephanie Booms, Elizabeth Hill, Leah Kulhanek, Jennifer Vredeveld, Brigid Gregg
Iodine deficiency is rare in the United States today, and this is largely due to the effectiveness of iodization in the general food supply. Recent trends among specific populations of children in the United States include adopting food restrictions, such casein-free and gluten-free diets. Although the effect of these types of diets on overall nutrition status and certain micronutrients has been studied in children with autism spectrum disorder, the effect of these limitations on iodine levels in children has not been assessed...
June 2016: Pediatrics
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