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Iodine deficiency

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https://www.readbyqxmd.com/read/28814477/iodine-excess-exposure-during-pregnancy-and-lactation-impairs-maternal-thyroid-function-in-rats
#1
Caroline Serrano-Nascimento, Rafael Salgueiro, Kaio Vitzel, Thiago Urgal Pantaleao, Vania Maria Correa da Costa, Maria Tereza Nunes
Adequate maternal iodine consumption during pregnancy and lactation guarantees normal thyroid hormones (TH) production, which is crucial to the development of the fetus. Indeed, iodine deficiency is clearly related to maternal hypothyroidism and deleterious effects in the fetal development. Conversely, the effects of iodine excess (IE) consumption on maternal thyroid function are still controversial. Therefore, this study aimed to investigate the impact of IE exposure during pregnancy and lactation periods on maternal hypothalamus-pituitary-thyroid axis...
August 16, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28803408/iodine-rich-herbs-and-potassium-iodate-have-different-effects-on-the-oxidative-stress-and-differentiation-of-th17-cells-in-iodine-deficient-nod-h-2-h4-mice
#2
Cheng-Han Gao, Jin-Qiao Qu, Xi-Yu Zhou, Tian-Shu Gao
Iodine-rich herbs such as seaweed, kelp, and sea tangle were widely used to treat various types of goiter with good effect and without any adverse side effects in China. When compared with potassium iodate (PI), iodine-rich herbs had a positive effect on the recovery of goiter resulting from iodine deficiency without any obvious harmful effects. In NOD.H-2(h4) mice, an autoimmune thyroiditis-prone model, iodine excess can increase infiltration of lymphocytes and structural damage of the thyroid follicles, hence resulting in thyroiditis...
August 12, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28802296/iodine-status-among-pregnant-women-in-rural-sabah-malaysia
#3
Kuang Kuay Lim, Ying Ying Chan, Chien Huey Teh, Hasimah Ismail, Rafidah Yusof, Jamail Muhi, Kuang Hock Lim, Leng Huat Foo
BACKGROUND AND OBJECTIVES: In 2000, legislation on mandatory universal salt iodisation was enacted in Sabah, Malaysia, to reduce the incidence of iodine deficiency disorders among its population. To evaluate the iodine levels among pregnant women from selected rural divisions in Sabah 13 years after the enactment of the universal salt iodisation programme. METHODS AND STUDY DESIGN: This cross-sectional study was conducted from 1 May to 30 June, 2013, in three rural divisions of Sabah (the Interior, the West Coast, and Kudat)...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28789730/iodine-status-of-postpartum-women-and-their-infants-in-australia-after-the-introduction-of-mandatory-iodine-fortification
#4
Dao Huynh, Dominique Condo, Robert Gibson, Beverly Muhlhausler, Philip Ryan, Sheila Skeaff, Maria Makrides, Shao J Zhou
Mandatory I fortification in bread was introduced in Australia in 2009 in response to the re-emergence of biochemical I deficiency based on median urinary I concentration (UIC)<100 µg/l. Data on the I status of lactating mothers and their infants in Australia are scarce. The primary aim of this study was to assess the I status, determined by UIC and breast milk I concentration (BMIC), of breast-feeding mothers in South Australia and UIC of their infants. The secondary aim was to assess the relationship between the I status of mothers and their infants...
June 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28781775/availability-of-adequately-iodized-in-northwest-ethiopia-a-cross-sectional-study
#5
Zegeye Abebe, Amare Tariku, Ejigu Gebeye
BACKGROUND: Universal salt iodization is the most cost-effective, safe and sustainable strategy to eliminate iodine deficiency disorders. However, little is known about the availability of adequately iodized salt in the northwestern part of Ethiopia. Thus, the aim of this study was to assess the availability of adequately iodized salt at the household level and associated factors in Dabat District, northwest Ethiopia. METHODS: A community-based cross-sectional study was conducted from February 21 to March 31, 2016...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28771408/promoting-early-child-development-with-interventions-in-health-and-nutrition-a-systematic-review
#6
REVIEW
Tyler Vaivada, Michelle F Gaffey, Zulfiqar A Bhutta
CONTEXT: Although effective health and nutrition interventions for reducing child mortality and morbidity exist, direct evidence of effects on cognitive, motor, and psychosocial development is lacking. OBJECTIVE: To review existing evidence for health and nutrition interventions affecting direct measures of (and pathways to) early child development. DATA SOURCES: Reviews and recent overviews of interventions across the continuum of care and component studies...
August 2017: Pediatrics
https://www.readbyqxmd.com/read/28770411/effect-of-iodine-nutrition-on-pregnancy-outcomes-in-an-iodine-sufficient-area-in-china
#7
Yue Xiao, Huakun Sun, Chenyan Li, Yongze Li, Shiqiao Peng, Chenling Fan, Weiping Teng, Zhongyan Shan
Many studies focused on the association between thyroid disease and pregnancy outcomes. The present study explored the effect of iodine nutrition during the first trimester on pregnancy outcomes. One thousand five hundred sixty-nine pregnant, euthyroid women at ≤12 weeks of gestation in an iodine-sufficient area in China were recruited. According to the World Health Organization (WHO) criteria for iodine nutrition during pregnancy, participants were divided into four groups: adequate iodine (median urinary iodine concentration (UIC), 150-249 μg/L), mild deficiency (UIC, 100-150 μg/L), moderate and severe deficiency (UIC, <100 μg/L), and more than adequate and excessive (UIC, ≥250 μg/L) groups...
August 2, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28766267/iodine-status-after-bariatric-surgery-a-prospective-10-year-report-from-the-swedish-obese-subjects-sos-study
#8
Sofia Manousou, Lena M S Carlsson, Robert Eggertsen, Lena Hulthén, Peter Jacobson, Kerstin Landin-Wilhelmsen, Penelope Trimpou, Per-Arne Svensson, Helena Filipsson Nyström
CONTEXT: Bariatric surgery can lead to nutrient deficiencies. Gastric by-pass (GBP) entails restriction and malabsorption, whereas, vertical banded gastroplasty (VBG) is only restrictive. OBJECTIVE: The objective of this study is to study whether GBP-patients develop iodine deficiency from malabsorption, and if GBP- and VBG-patients develop lower 24-h urinary iodine excretion (24-UIE) than obese non-operated controls (OB-controls) due to lower iodine intake. DESIGN: The Swedish Obese Subjects (SOS) study is a prospective, non-randomized study of 4047 obese patients included 1987-2001, who chose bariatric surgery or non-surgical treatment...
August 2, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28760114/assessing-selenium-manganese-and-iodine-status-in-pediatric-patients-receiving-parenteral-nutrition
#9
Jacob Clarke Johnsen, Susan Anne Reese, Mark Mackay, Collin R Anderson, Daniel Jackson, Irasema Libertad Paul
BACKGROUND: Pediatric patients who are receiving parenteral nutrition (PN) unsupplemented with trace minerals can become deficient. Due to shortages in trace mineral products and the 2004 American Society for Parenteral and Enteral Nutrition report stating that individualized trace element supplementation may be warranted, a review was conducted concerning the trace minerals selenium (Se), manganese (Mn), and iodine (I). METHOD: A retrospective review of pediatric patients receiving PN that contained Se and Mn was conducted to determine if a difference existed between them and patients receiving PN without Se and Mn...
August 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28760007/double-fortified-salt-intervention-improved-iron-intake-but-not-energy-and-other-nutrient-intakes-in-female-tea-plantation-workers-from-west-bengal-india
#10
Sudha Venkatramanan, Grace Marquis, Lynnette Neufeld, Michael Wenger, Laura Murray-Kolb, Gregory Reinhart, Jere Haas
BACKGROUND: Iron deficiency is a global public health concern and has implications on the health status of women in reproductive age. OBJECTIVE: We hypothesized that improving iron intake with double fortified salt would improve food intake, resulting in higher energy, nutrient intakes, and weight indicators of female tea plantation workers. METHODS: In this randomized double-masked study, the participants (n = 245) were assigned to receive salt double fortified with iron and iodine (DFS; treatment) or salt fortified with iodine (control) and followed for 7...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28756810/serum-thyroglobulin-a-sensitive-biomarker-of-iodine-nutrition-status-and-affected-by-thyroid-abnormalities-and-disease-in-adult-populations
#11
Yang DU, Yan Hui Gao, Zhuo Ying Feng, Fan Gang Meng, Li Jun Fan, Dian Jun Sun
OBJECTIVE: To evaluate the usefulness of the thyroglobulin (Tg) level in adults as a nutritional biomarker of iodine status and to identify the factors related to the serum Tg level. METHODS: A cross-sectional study was conducted in adult populations of areas differing in iodine nutrition from three provinces (Autonomous Region) in China. Serum levels of thyroid hormones and Tg as well as thyroid autoantibodies were measured. The thyroid volume and nodule were measured by ultrasound...
July 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28749486/milestones-and-controversies-in-maternal-and-child-health-examining-a-brief-history-of-micronutrient-fortification-in-the-us
#12
A Deavenport-Saman, A Britt, K Smith, R A Jacobs
Fortification of our food and drinking supply has decreased morbidity rates related to micronutrient deficiencies among mothers and their children, particularly during the perinatal and neonatal periods of development. The purpose of this historical review is to examine the impact of public policy changes related to micronutrient fortification. We provide a historical investigation of achievements and controversies related to iodine, vitamin D, fluoride and folic acid fortifications in our food and drinking supply...
July 27, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28749399/re-establishment-of-normal-radioactive-iodine-uptake-reference-range-in-the-era-of-universal-salt-iodization-in-the-indian-population
#13
Sanjana Ballal, Ramya Soundararajan, Chandrasekhar Bal
BACKGROUND & OBJECTIVES: The reference radioactive iodine uptake (RAIU) values established in the 1970s in the era of widespread iodine deficiency were relatively high. Now, after four decades of successful Universal Salt Iodization (USI) programme in India, there is a need to re-establish these reference ranges. The present study was aimed to quantify the two-hour and 24-h RAIU values in iodine sufficient euthyroid individuals and validate the results in Graves' and Hashimoto's thyroiditis patients...
March 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28748081/comparison-of-two-sources-of-iodine-delivery-on-breast-milk-iodine-and-maternal-and-infant-urinary-iodine-concentrations-in-southern-ethiopia-a-randomized-trial
#14
Tafere Gebreegziabher, Barbara J Stoecker
Iodine deficiency during pregnancy and lactation could expose the infant to severe iodine deficiency disorders. A randomized supplementation trial among rural lactating women was conducted in Sidama zone, southern Ethiopia, to compare the methods of iodine delivery on breast milk iodine, and on maternal and infant urinary iodine concentrations. Women were randomly assigned either to receive 225 μg iodine as potassium iodide capsule daily for 6 months or 450 g of appropriately iodized salt (30-40 μg I as KIO3/g of salt) weekly for household consumption for 6 months...
July 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28746059/nutrition-micronutrients-in-child-growth-and-development-a-systematic-review-on-current-evidence-recommendations-and-opportunities-for-further-research
#15
Mohammad Yawar Yakoob, Clifford W Lo
OBJECTIVE: An important aspect of malnutrition is deficiency of different micronutrients during pregnancy or early childhood. We systematically reviewed the role of nutrition in child growth (weight or height gain) and development. METHODS: A comprehensive literature search was done on PubMed/Cochrane Library browsing through 38,795 abstracts until December 31, 2016 to select systematic reviews/meta-analyses and individual randomized controlled trials (RCTs) of micronutrient supplementation...
July 25, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28737011/a-distinctive-patchy-osteomalacia-characterises-phospho1-deficient-mice
#16
Alan Boyde, Katherine A Staines, Behzad Javaheri, Jose Luis Millan, Andrew A Pitsillides, Colin Farquharson
The phosphatase PHOSPHO1 is involved in the initiation of biomineralisation. Bones in Phospho1 knockout (KO) mice show histological osteomalacia with frequent bowing of long bones and spontaneous fractures: they contain less mineral, with smaller mineral crystals. However, the consequences of Phospho1 ablation on the microscale structure of bone are not yet fully elucidated. Tibias and femurs obtained from wild-type and Phospho1 null (KO) mice (25-32 weeks old) were embedded in PMMA, cut and polished to produce near longitudinal sections...
August 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28736886/size-of-thyroid-carcinoma-by-histotype-and-variants-a-population-based-study-in-a-mildly-iodine-deficient-area
#17
Michela Marina, Gian Paolo Ceda, Luigi Corcione, Paolo Sgargi, Maria Michiara, Enrico Maria Silini, Graziano Ceresini
BACKGROUND: Data relating the size of thyroid cancer with histological types and variants are scarce. METHODS: All incident thyroid cancer diagnosed between 2003 and 2012 in a mildly iodine-deficient area were derived from a population-based tumor registry. Undifferentiated/anaplastic thyroid cancer and incidental cases were excluded. Major diameter of thyroid cancer, as assessed by pathological examination, was stratified in classes: ≤10 mm; 11-20 mm; 21-40 mm; and >40 mm...
July 24, 2017: Head & Neck
https://www.readbyqxmd.com/read/28727455/electron-deficient-chiral-lactic-acid-based-hypervalent-iodine-reagents
#18
Jihan Qurban, Mohamed Elsherbini, Thomas Wirth
Novel electron-deficient chiral hypervalent iodine reagents were prepared in good overall yields. The reactivity and stereoselectivity of these reagents in oxidative rearrangements of alkenes to α-aryl ketones was investigated. The results show that the new reagents have good reactivity and generate products with high enantiomeric excess.
July 20, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28720593/vitamin-a-endocrine-tissues-and-hormones-interplay-and-interactions
#19
Julie Brossaud, Veronique Pallet, Jean-Benoit Corcuff
Vitamin A (retinol) is a micronutrient critical for cell proliferation and differentiation. In adults, vitamin A and metabolites such as retinoic acid (RA) play major roles in vision, immune and brain functions, and tissue remodelling and metabolism. This review presents the physiological interactions of retinoids and endocrine tissues and hormonal systems. Two endocrine systems have been particularly studied. In the pituitary, retinoids targets the corticotrophs with a possible therapeutic use in corticotropinomas...
July 18, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28694389/are-lower-tsh-cutoffs-in-neonatal-screening-for-congenital-hypothyroidism-warranted-a-debate
#20
Samantha Lain, Caroline Trumpff, Scott D Grosse, Antonella Olivieri, Guy Van Vliet
When newborn screening (NBS) for congenital hypothyroidism (CH) using thyroid stimulating hormone (TSH) as a primary screening test was introduced, typical TSH screening cutoffs were 20 to 50 mU/L of whole blood. Over the years, lowering of TSH cutoffs has contributed to an increased prevalence of detected CH. However, a consensus on the benefit deriving from lowering TSH cutoffs at screening is lacking. The present paper outlines arguments both for and against the lowering of TSH cutoffs at NBS. It includes a review of recently published evidence from Australia, Belgium, and Italy...
July 10, 2017: European Journal of Endocrinology
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