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Iodine deficiency

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https://www.readbyqxmd.com/read/29052174/phagocytosis-deficiency-of-macrophages-in-nod-h-2-h4-mice-accelerates-the-severity-of-iodine-induced-autoimmune-thyroiditis
#1
Xue He, Chuhui Xiong, Aihua Liu, Wei Zhao, Xinghai Xia, Shiqiao Peng, Chenyan Li, Mi Zhou, Yushu Li, Xiaoguang Shi, Zhongyan Shan, Weiping Teng
Apoptosis occurs in many autoimmune diseases. Excess iodine induces thyrocyte apoptosis and increases the incidence and prevalence of autoimmune thyroiditis (AIT). However, the sequence of events between the appearance of thyrocyte apoptosis and the occurrence of thyroiditis remains uncharacterized. Furthermore, few studies have investigated the role of macrophage phagocytosis in the development of AIT. Therefore, we evaluated the relationship between apoptosis and inflammatory infiltration in NOD.H-2(h4) mouse thyroids by comparing the sequence of events in tissue samples...
October 20, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29050705/iodine-nutritional-status-in-asturian-schoolchildren
#2
María Riestra Fernández, Edelmiro Menéndez Torre, Francisco Díaz Cadórniga, Juan Carlos Fernández Fernández, Elías Delgado Álvarez
INTRODUCTION: Iodine deficiency is a public health problem, and iodine nutritional status should therefore be regularly measured. OBJECTIVE: To ascertain iodine nutritional status in Asturias and its relation to use of iodized salt and to other sociodemographic and nutritional parameters. MATERIAL AND METHODS: A descriptive, observational study was conducted in a random sample of schoolchildren aged 5 to 14 years, in whom urinary iodine levels were measured by high-performance liquid chromatography...
November 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/29050668/microbial-transformation-of-iodine-from-radioisotopes-to-iodine-deficiency
#3
Chris M Yeager, Seigo Amachi, Russell Grandbois, Daniel I Kaplan, Chen Xu, Kathy A Schwehr, Peter H Santschi
Iodine is a biophilic element that is important for human health, both as an essential component of several thyroid hormones and, on the other hand, as a potential carcinogen in the form of radioiodine generated by anthropogenic nuclear activity. Iodine exists in multiple oxidation states (-1, 0, +1, +3, +5, and +7), primarily as molecular iodine (I2), iodide (I(-)), iodate [Formula: see text] , or organic iodine (org-I). The mobility of iodine in the environment is dependent on its speciation and a series of redox, complexation, sorption, precipitation, and microbial reactions...
2017: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/29033409/evaluation-of-serum-ferritin-and-thyroid-function-in-the-second-trimester-of-pregnancy
#4
Leqi He, Chunmei Shen, Yanan Zhang, Zaoping Chen, Heyuan Ding, Jun Liu, Bingbing Zha
Ferritin is a universal intracellular protein that acts as an iron carrier. Several studies have indicated that iron deficiency affects thyroid function in non-pregnant women. Our objective was to assess the relationship between serum ferritin levels and thyroid function in pregnant women during the second trimester. Pregnant women with sufficient iodine intake and normal antithyroid antibodies during the second trimester were recruited from the obstetric outpatient department of the Fifth People's Hospital of Fudan University...
October 13, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29032778/has-iodized-salt-reduced-iodine-deficiency-disorders-among-school-aged-children-in-north-west-iran-a-9-year-prospective-study
#5
Sakineh Nouri Saeidlou, Fariba Babaei, Parvin Ayremlou, Rasoul Entezarmahdi
OBJECTIVE: Low iodine intakes are associated with goitre and other iodine-deficiency disorders (IDD) that have affected billions of people worldwide. We aimed to assess total goitre rate (TGR) and urinary iodine concentration (UIC) in schoolchildren between 2007 and 2015, percentage of iodized salt consumption by households, and salt iodine content at production, distribution and household levels in north-west Iran. Design/Setting/Subjects UIC assessed among schoolchildren in nine consecutive years; 240 schoolchildren aged 8-10 years selected by systematic random sampling each year in the West Azerbaijan Province...
October 16, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29030200/iodine-supplementation-in-pregnancy-in-mildly-deficient-regions
#6
Sarah C Bath
No abstract text is available yet for this article.
October 10, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29030199/effect-of-iodine-supplementation-in-pregnant-women-on-child-neurodevelopment-a-randomised-double-blind-placebo-controlled-trial
#7
Sueppong Gowachirapant, Nidhi Jaiswal, Alida Melse-Boonstra, Valeria Galetti, Sara Stinca, Ian Mackenzie, Susan Thomas, Tinku Thomas, Pattanee Winichagoon, Krishnamachari Srinivasan, Michael B Zimmermann
BACKGROUND: Iodine deficiency during pregnancy might be associated with reduced intelligence quotient (IQ) score in offspring. We assessed the effect of iodine supplementation in mildly iodine-deficient pregnant women on neurodevelopment of their offspring in areas where schoolchildren were iodine sufficient. METHODS: In this randomised, placebo-controlled trial, pregnant women in Bangalore, India, and Bangkok, Thailand, were randomly assigned (1:1) to receive 200 μg iodine orally once a day or placebo until delivery...
October 10, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29027055/socio-demographic-characters-distribution-and-transformation-of-iodine-in-soil-plant-and-wheat-grains-at-district-diamer-gilgit-baltistan-pakistan
#8
Faridullah, Didar Ahmad, Hina Shabbir, Toqeer Ahmed, Muhammad Irshad, Arif Alam, Asif Sardar
Iodine deficiency in soils and plants is a common problem in the hilly areas and has still been ignored. The aim of the current study is to investigate associated health issues, socio-economic characteristics and people's perception regarding iodine deficiency. Furthermore, a follow-up study was conducted to determine iodine and nutrients concentration in soil and crops at District Diamer, Gilgit-Baltistan, Pakistan. A descriptive and empirical analysis was examined. Most importantly, male was significantly observed as more affected for iodine deficiency than female, as contrary to the literature, socio-economic factors such as households' income and awareness (education) are reported as negative and significant contributor to reduce the iodine deficiency among the people irrespective of the gender...
October 12, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/29019745/imaging-of-nonmalignant-adrenal-lesions-in-children
#9
Kiran M Sargar, Geetika Khanna, Rebecca Hulett Bowling
The adrenal glands in children can be affected by a variety of benign lesions. The diagnosis of adrenal lesions can be challenging, but assessment of morphologic changes in correlation with the clinical presentation can lead to an accurate diagnosis. These lesions can be classified by their cause: congenital (eg, discoid adrenal gland, horseshoe adrenal gland, and epithelial cysts), vascular and/or traumatic (eg, adrenal hemorrhage), infectious (eg, granulomatous diseases), enzyme deficiency disorders (eg, congenital adrenal hyperplasia [CAH] and Wolman disease), benign neoplasms (eg, pheochromocytomas, ganglioneuromas, adrenal adenomas, and myelolipomas), and adrenal mass mimics (eg, extralobar sequestration and extramedullary hematopoiesis)...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29016579/iodine-and-thyroid-function-status-and-anti-thyroid-peroxidase-antibody-among-pregnant-women-in-eastern-nepal
#10
Lalit Narayan Chaudhary, Saroj Khatiwada, Basanta Gelal, Sharad Gautam, Madhab Lamsal, Hanoon Pokharel, Nirmal Baral
BACKGROUND: Iodine deficiency, thyroid dysfunction and development of thyroid autoimmunity during pregnancy may affect mother and the developing fetus. This study was carried out to find iodine status, thyroid dysfunction and thyroid autoimmunity among pregnant women. METHODS: Ninety two pregnant women from three districts of eastern Nepal (Sunsari, Morang and Jhapa) were enrolled for the study, and urine and blood samples were collected. Urinary iodine concentration (UIC), free thyroxine (free T4), thyroid stimulating hormone (TSH), thyroglobulin and anti-thyroid peroxidase (TPO) antibody levels were estimated...
September 8, 2017: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28982133/simultaneous-assessment-of-iodine-iron-vitamin-a-malarial-antigenemia-and-inflammation-status-biomarkers-via-a-multiplex-immunoassay-method-on-a-population-of-pregnant-women-from-niger
#11
Eleanor Brindle, Lorraine Lillis, Rebecca Barney, Sonja Y Hess, K Ryan Wessells, Césaire T Ouédraogo, Sara Stinca, Michael Kalnoky, Roger Peck, Abby Tyler, Christopher Lyman, David S Boyle
Deficiencies of vitamin A, iron, and iodine are major public health concerns in many low- and middle-income countries, but information on their status in populations is often lacking due to high costs and logistical challenges associated with assessing micronutrient status. Accurate, user-friendly, and low-cost analytical tools are needed to allow large-scale population surveys on micronutrient status. We present the expansion of a 7-plex protein microarray tool for the simultaneous measurement of up to seven biomarkers with relevance to the assessment of the key micronutrients iron, iodine, and vitamin A, and inflammation and malaria biomarkers: α-1-acid glycoprotein, C-reactive protein, ferritin, retinol binding protein 4, soluble transferrin receptor, thyroglobulin, and histidine-rich protein II...
2017: PloS One
https://www.readbyqxmd.com/read/28981457/micronutrient-status-and-dietary-intake-of-iron-vitamin-a-iodine-folate-and-zinc-in-women-of-reproductive-age-and-pregnant-women-in-ethiopia-kenya-nigeria-and-south-africa-a-systematic-review-of-data-from-2005-to-2015
#12
REVIEW
Rajwinder Harika, Mieke Faber, Folake Samuel, Judith Kimiywe, Afework Mulugeta, Ans Eilander
A systematic review was conducted to evaluate the status and intake of iron, vitamin A, iodine, folate and zinc in women of reproductive age (WRA) (≥15-49 years) and pregnant women (PW) in Ethiopia, Kenya, Nigeria and South Africa. National and subnational data published between 2005 and 2015 were searched via Medline, Scopus and national public health websites. Per micronutrient, relevant data were pooled into an average prevalence of deficiency, weighted by sample size (WAVG). Inadequate intakes were estimated from mean (SD) intakes...
October 5, 2017: Nutrients
https://www.readbyqxmd.com/read/28981159/hypervalent-aryliodine-compounds-as-precursors-for-radiofluorination
#13
Victor W Pike
Over the last two decades or so, hypervalent iodine compounds, such as diaryliodonium salts and aryliodonium ylides, have emerged as useful precursors for labeling homoarenes and heteroarenes with no-carrier-added cyclotron-produced [(18) F]fluoride ion (t1/2 = 109.8 min). They permit rapid and effective radiofluorination at electron-rich as well as electron-deficient aryl rings, and often with unrestricted choice of ring position. Consequently, hypervalent aryliodine compounds have found special utility as precursors to various small-molecule (18) F-labeling synthons and to many radiotracers for biomedical imaging with positron emission tomography...
October 5, 2017: Journal of Labelled Compounds & Radiopharmaceuticals
https://www.readbyqxmd.com/read/28969507/societal-costs-of-micronutrient-deficiencies-in-6-to-59-month-old-children-in-pakistan
#14
Simon Wieser, Beatrice Brunner, Christina Tzogiou, Rafael Plessow, Michael B Zimmermann, Jessica Farebrother, Sajid Soofi, Zaid Bhatti, Imran Ahmed, Zulfiqar A Bhutta
BACKGROUND: In Pakistan, nearly half of children younger than 5 years are stunted and 1 in 3 is underweight. Micronutrient deficiencies, a less visible form of undernutrition, are also endemic. They may lead to increased morbidity and mortality as well as to impaired cognitive and physical development. OBJECTIVE: To estimate the lifetime costs of micronutrient deficiencies in Pakistani children aged between 6 and 59 months. METHODS: We develop a health economic model of the lifetime health and cost consequences of iodine, iron, vitamin A, and zinc deficiencies...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28965575/severe-selenium-deficits-in-pregnant-women-irrespective-of-autoimmune-thyroid-disease-in-an-area-with-marginal-selenium-intake
#15
Urszula Ambroziak, Sandra Hybsier, Urszula Shahnazaryan, Małgorzata Krasnodębska-Kiljańska, Eddy Rijntjes, Zbigniew Bartoszewicz, Tomasz Bednarczuk, Lutz Schomburg
OBJECTIVES: Selenium (Se) deficiency is related to an increased risk of preterm labor, miscarriage, preeclampsia, gestational diabetes, and other obstetric complications. As the Se status declines during pregnancy, we hypothesized that the decline may be exacerbated in women with autoimmune thyroid disease (AITD). MATERIAL AND METHODS: Pregnant women (n=74; 30 [23-38] years) were consecutively recruited from the district of Warsaw, Poland, and divided into healthy subjects (HS, n=45), and women with a diagnosis of AITD (AITD, n=29)...
December 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28953213/body-iodine-status-in-women-with-postmenopausal-osteoporosis
#16
Tufan Arslanca, Vakkas Korkmaz, Seyma B Arslanca, Burak Karadag, Yusuf Ergün
OBJECTIVE: Postmenopausal osteoporosis is a frequent cause of morbidity and can negatively impact life expectancy; iodine is an essential element for bone mineralization, and iodine deficiency is frequently observed. The aim of the present study was to understand the connection between postmenopausal osteoporosis and the level of iodine in the body. METHODS: A total of 132 participants were divided into three groups: group 1 consisted of healthy postmenopausal women (n = 34), group 2 comprised osteopenic women (n = 38), and group 3 included women with postmenopausal osteoporosis (n = 60)...
September 25, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28946925/iodine-concentration-of-milk-alternative-drinks-available-in-the-uk-in-comparison-with-cows-milk
#17
Sarah C Bath, Sarah Hill, Heidi Goenaga Infante, Sarah Elghul, Carolina J Nezianya, Margaret P Rayman
Iodine deficiency is present in certain groups of the UK population, notably in pregnant women; this is of concern as iodine is required for fetal brain development. UK milk is rich in iodine and is the principal dietary iodine source. UK sales of milk-alternative drinks are increasing but data are lacking on their iodine content. As consumers may replace iodine-rich milk with milk-alternative drinks, we aimed to measure the iodine concentration of those available in the UK. Using inductively coupled plasma-MS, we determined the iodine concentration of seven types of milk-alternative drink (soya, almond, coconut, oat, rice, hazelnut and hemp) by analysing forty-seven products purchased in November/December 2015...
October 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28946048/ph-dependent-synthesis-of-iodine-deficient-bismuth-oxyiodide-microstructures-visible-light-photocatalytic-activity
#18
Gongjuan Wu, Yan Zhao, Yawen Li, Hongmei Ma, Jingzhe Zhao
Bismuth oxyiodides have exhibited high potential for applications in visible-light photocatalytic environmental remediation and solar energy conversion. In this work, a series of iodine-deficient bismuth oxyiodides (Bi4O5I2, Bi7O9I3, Bi5O7I) can be simply prepared through a pH-dependent aqueous procedure with feeding Bi/I ratio of 2:1. The compositions of the Bi-based oxyiodides are closely related to acid-base circumstances, with Bi4O5I2 formed in weakly acidic medium (pH = 5) and Bi7O9I3, Bi5O7I in basic medium (pH = 8 and 11)...
September 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28936757/vitamin-d-deficiency-affects-thyroid-autoimmunity-and-dysfunction-in-iodine-replete-area-korea-national-health-and-nutrition-examination-survey
#19
Mijin Kim, Eyun Song, Hye-Seon Oh, Suyeon Park, Hyemi Kwon, Min Ji Jeon, Won Gu Kim, Won Bae Kim, Young Kee Shong, Tae Yong Kim
PURPOSE: We evaluated the effects of vitamin D levels and iodine intake on thyroid autoimmunity and dysfunction in the Korean population. METHODS: In this nationwide population-based study, data were obtained from the Korea National Health and Nutrition Examination Survey VI-1 and 2 (2013 and 2014), which was the first nationwide survey that measured both serum 25-hydroxy vitamin D [25(OH)D] levels and urinary iodine concentrations (UICs) in Korea. A total of 4181 participants who underwent laboratory tests for thyroid function, serum 25(OH)D levels, and UICs were included...
September 21, 2017: Endocrine
https://www.readbyqxmd.com/read/28925418/mhealth-application-areas-and-technology-combinations-a-comparison-of-literature-from-high-and-low-middle-income-countries
#20
Haitham Abaza, Michael Marschollek
BACKGROUND: With the continuous and enormous spread of mobile technologies, mHealth has evolved as a new subfield of eHealth. While eHealth is broadly focused on information and communication technologies, mHealth seeks to explore more into mobile devices and wireless communication. Since mobile phone penetration has exceeded other infrastructure in low and middle-income countries (LMICs), mHealth is seen as a promising component to provide pervasive and patient-centered care. OBJECTIVES: The aim of our research work for this paper is to examine the mHealth literature to identify application areas, target diseases, and mHealth service and technology types that are most appropriate for LMICs...
August 8, 2017: Methods of Information in Medicine
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