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Iodine deficiency

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https://www.readbyqxmd.com/read/29446011/continuously-sustained-elimination-of-iodine-deficiency-a-quarter-of-a-century-success-in-the-islamic-republic-of-iran
#1
H Delshad, P Mirmiran, Z Abdollahi, F Salehi, F Azizi
BACKGROUND: Iodine deficiency and related disorders were very common in Iran prior to 1996, when universal salt iodization (USI) was implemented and in 2000 Iran was declared iodine deficiency disorders (IDD) free. The aim of this study was to evaluate the adequacy of iodine intake by Iranian households in all 30 provinces of Iran, a quarter of a century after the intervention. METHODS: A total of 18,000 school-aged children (8-10 years with mean 8.7 ± 1 year) were included in this study...
February 14, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29413100/interaction-between-iodine-and-glucosinolates-in-rutabaga-sprouts-and-selected-biomarkers-of-thyroid-function-in-male-rats
#2
Paweł Paśko, Krzysztof Okoń, Mirosław Krośniak, Ewelina Prochownik, Paweł Żmudzki, Jadwiga Kryczyk-Kozioł, Paweł Zagrodzki
Rutabaga sprouts belong to the Brassicaceae family and may exert a negative influence on thyroid function, because they are a rich in glucosinolates. These sprouts are also valuable source of iodine (6.5 ± 0.6 μg/100 g of fresh weight). Sprouts were tested in a long-term experiment with young male rats as an element of their diet, combined with two models of hypothyroidism, the first - deficit of iodine and the second - sulfadimethoxine ingestion as a pharmacological agent caused inhibition of thyroid peroxidase...
March 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29413098/status-and-interrelationship-of-toenail-elements-in-pacific-children
#3
Shamshad Karatela, Neil I Ward, Irene Suilan Zeng, Janis Paterson
OBJECTIVE: Elemental deficiencies or in excess effects growth and development. Pacific population are at a disadvantage due to food insecurity as compared to New Zealand European households. This study aims to evaluate the status and interrelationship of elements (essential, non-essential and toxic) in nine-year-old Pacific children who were part of the Pacific Island Families Study living in New Zealand. MATERIALS AND METHODS: This observational study included 278 eligible nine-year-old children...
March 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29407004/breast-milk-is-conditionally-perfect
#4
Miriam Erick
Breast milk is the universal preferred nutrition for the newborn human infant. New mother have been encouraged to exclusively breastfeed by health care professionals and consumer-advocacy forums for years, citing "breast milk is the perfect food". The benefits are numerous and include psychological, convenience, economical, ecological and nutritionally superior. Human milk is a composite of nutritional choices of the mother, commencing in the pre-conceptual era. Events influencing the eventual nutritional profile of breast milk for the neonate start with pre-conceptual dietary habits through pregnancy and finally to postpartum...
February 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29402856/evaluation-of-dynamic-thiol-disulphide-homeostasis-in-children-and-adolescents-with-non-autoimmune-subclinical-hypothyroidism
#5
Seyit Ahmet Ucakturk, Murat Alışık, Çagatay Ugur, Selin Elmaogullari, Eda Mengen, Özcan Erel
<br>To evaluate the thiol/disulphide homeostasis in children with non-autoimmune subclinical hypothyroidism. <br> Materials (Subjects) and Methods<br>Thiol-disulphide homeostasis [native thiol-disulphide exchanges (native thiol (SH), disulphide (SS), and total thiol (SS+SH))] was evaluated in 60 children and adolescents who were negative for thyroid auto-antibodies (anti-thyroid peroxidase, anti-thyroglobulin) and had a TSH value higher than 5 mIU/L and in 40 sex- and age-matched healthy control subjects who were negative for thyroid auto-antibodies and had normal TSH levels...
January 25, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29402848/do-statins-affect-thyroid-volume-and-nodule-size-in-patients-with-hyperlipidemia-in-a-mildly-to-moderately-iodine-deficient-region-a-prospective-study
#6
Canan Demir, Cuneyd Anil, Yusuf Bozkus, Umut Mousa, Altug Kut, Asli Nar, Neslihan B Tutuncu
OBJECTIVE: The objective of this study was to assess the anti-proliferative pleiotropic effects of statins on thyroid function, volume and nodularity. SUBJECTS AND METHODS: One hundred and six hyperlipidemic patients were included in this prospective study. Sixty nine patients in the statin groups received atorvastatin (16 patients received 10 mg, 18 received 20 mg) or rosuvastatin (20 patients received 10 mg, 15 received 20 mg); 37 patients in the control group assessed as not requiring drugs only made lifestyle changes...
January 23, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29386451/-recent-trends-of-trace-element-studies-in-clinical-medicine-in-japan
#7
Hiroko Kodama
The deficiency or excess intake of trace elements, including zinc, copper, selenium and iodine, has often been reported. Zinc deficiency is often observed in infants fed breast milk with low zinc concentration, individuals administered chelating medicines, athletes and patients with diabetes mellitus, hepatic cirrhosis or nephrosis syndrome. Menkes disease is associated with severe copper deficiency, and there is no effective treatment. Deficiencies of selenium and iodine are observed in patients who receive special formulas of milk and enteral formula with low selenium and iodine concentrations, respectively...
2018: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
https://www.readbyqxmd.com/read/29360482/biomonitoring-equivalents-for-interpretation-of-urinary-iodine
#8
Sean M Hays, Devika Poddalgoda, Kristin Macey, Lesa Aylward, Andy Nong
Iodine is an essential nutrient whose deficiency or excess exposure can cause adverse health effects. The primary sources of iodine exposure in the general population are iodized salt, dairy products, bread and sea food. Urinary iodine concentrations (UIC) have been measured by Canadian Health Measures Survey (CHMS) and US National Health and Nutrition Examination Survey (NHANES). The Institute of Medicine (IOM), the US Agency for Toxic Substances and Disease Registry (ATSDR) and World Health Organization (WHO) have established exposure guidance values for nutrition (IOM Estimated Average Requirement (EAR), Recommended Dietary Allowance (RDA), WHO Recommended Nutrient Intake (RNI)) and toxicity (IOM Tolerable Upper Intake Level (UL); ATSDR Minimal Risk Level (MRL), WHO International Programme on Chemical Safety (IPCS) Tolerable Daily Intake (TDI))...
January 19, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29358829/the-bioaccessibility-of-iodine-in-the-biofortified-vegetables-throughout-cooking-and-simulated-digestion
#9
Rui Li, De-Wang Li, Ai-Lan Yan, Chun-Lai Hong, Hui-Ping Liu, Le-Hua Pan, Ming-Yi Song, Zhi-Xi Dai, Ming-Li Ye, Huan-Xin Weng
Biofortification of crops with exogenous iodine is a novel strategy to control iodine deficiency disorders (IDD). The bioaccessibility of iodine (BI) in the biofortified vegetables in the course of soaking, cooking and digestion, were examined. Under hydroponics, the concentration of iodine in leafstalks of the celery and pakchoi increased with increasing exogenous iodine concentration, 54.8-63.9% of the iodine absorbed by pakchoi was stored in the soluble cellular substance. Being soaked in water within 8 h, the iodine loss rate of the biofortified celery was 3...
January 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29344036/primordial-and-primary-preventions-of-thyroid-disease
#10
REVIEW
Fereidoun Azizi, Ladan Mehran, Farhad Hosseinpanah, Hossein Delshad, Atieh Amouzegar
Background: Primordial and primary preventions of thyroid diseases are concerned with avoiding the appearance of risk factors, delaying the progression to overt disease, and minimizing the impact of illness. Summary: Using related key words, 446 articles related to primordial and primary, preventions of thyroid diseases published between 2001-2015 were evaluated, categorized and analyzed. Prevention and elimination of iodine deficiency are major steps that have been successfully achieved and maintained in many countries of the world in last 2 decades...
October 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29342090/development-of-databases-on-iodine-in-foods-and-dietary-supplements
#11
REVIEW
Abby G Ershow, Sheila A Skeaff, Joyce M Merkel, Pamela R Pehrsson
Iodine is an essential micronutrient required for normal growth and neurodevelopment; thus, an adequate intake of iodine is particularly important for pregnant and lactating women, and throughout childhood. Low levels of iodine in the soil and groundwater are common in many parts of the world, often leading to diets that are low in iodine. Widespread salt iodization has eradicated severe iodine deficiency, but mild-to-moderate deficiency is still prevalent even in many developed countries. To understand patterns of iodine intake and to develop strategies for improving intake, it is important to characterize all sources of dietary iodine, and national databases on the iodine content of major dietary contributors (including foods, beverages, water, salts, and supplements) provide a key information resource...
January 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29340973/reference-intervals-for-thyrotropin-in-an-area-of-northern-italy-the-pordenone-thyroid-study-tripp
#12
R Tozzoli, F D'Aurizio, P Metus, A Steffan, C Mazzon, M Bagnasco
PURPOSE: Thyrotropin (TSH) is the most accurate marker of thyroid dysfunction in the absence of pituitary or hypothalamic disease. Studies on TSH reference intervals (RIs) showed wide inter-individual variability and prompted an intense debate about the best estimation of TSH RIs. DESIGN: We performed a population study on TSH RIs, using current data stored in the laboratory information system (LIS), at the Hospital Department of Laboratory Medicine, Pordenone (Italy), historically an area of mild-moderate iodine deficiency with a relatively high goiter prevalence...
January 16, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29340704/delayed-conception-in-women-with-low-urinary-iodine-concentrations-a-population-based-prospective-cohort-study
#13
J L Mills, G M Buck Louis, K Kannan, J Weck, Y Wan, J Maisog, A Giannakou, Q Wu, R Sundaram
STUDY QUESTION: Is iodine deficiency associated with decreased fecundability? SUMMARY ANSWER: Moderate to severe iodine deficiency is associated with a 46% decrease in fecundability. WHAT IS KNOWN ALREADY: Iodine deficiency is common in women of childbearing age but its effect on fecundability has not been investigated. STUDY DESIGN, SIZE, DURATION: The LIFE Study, a population-based prospective cohort study, enrolled 501 women who had discontinued contraception within 2 months to become pregnant between 2005 and 2009...
January 11, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29340407/t-buona-mediated-direct-c-h-halogenation-of-electron-deficient-hetero-arenes
#14
Xia Liu, Xin Zhao, Fushun Liang, Baoyi Ren
An efficient halogenation of electron-deficient (hetero)arenes is described. The reaction utilizes common t-BuONa as a catalyst (for iodination) or a promoter (for bromination and chlorination), and perfluorobutyl iodide, CBr4 or CCl4 as the readily-available halogenating agents, respectively. The protocol features broad scope, high efficiency, mild conditions and gram scalability. An ionic pathway involving halogen bond formation and halophilic attack is proposed. The utility of the resulting iodinated heteroarenes is demonstrated in visible light-mediated Caryl-Caryl cross-coupling reaction...
January 17, 2018: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29335065/effects-of-maternal-marginal-iodine-deficiency-on-interactions-between-cerebellar-bergmann-glia-cells-and-purkinje-cells-in-rat-offspring
#15
Ye Yu, Jing Dong, Yuan Wang, Yi Wang, Hui Min, Zhong Yan Shan, Wei Ping Teng, Jie Chen
Iodine deficiency (ID) during early pregnancy has an adverse effect on children's psychomotor and motor function but the mechanism has not been clarified. Therefore, our aim was to study the effect of maternal marginal ID on cerebellar neurodevelopment and the underlying mechanism. After obtaining marginal ID rats, we examined interactions between Bergmann glia cells (BGs) and Purkinje cells (PCs) using immunofluorescence and expression of the glutamate transporter and receptor by western blot. Our results showed that marginal ID reduced the number of contacted points between BGs and PCs, and disturbed expression of the glutamate transporter and receptor...
December 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/29334717/-the-ten-year-retrospect-of-nutrition-and-health-status-of-pregnant-women-in-china
#16
C X Dong, S A Yin
Improvement of the nutrition and health status of pregnant women should be one of the top priority strategies of improving the physical fitness of next generation and reserve of talented person for national sustainable development. This paper reviews the nutrition and health status of pregnant women in China over the recent ten years and discusses the underlying factors and changing trends. The most popular nutrition-related problem is dietary imbalance, and many micronutrient intakes are lower than the recommended dietary intakes or adequate intakes, and some of nutrient intakes are still at a very low level for a long time such as vitamin D and calcium...
January 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29334343/breast-milk-iodine-concentrations-and-iodine-levels-of-infants-according-to-the-iodine-status-of-the-country-of-residence-a-systematic-review-and-meta-analysis
#17
Pantea Nazeri, Ali Kabir, Hosein Dalili, Parvin Mirmiran, Fereidoun Azizi
BACKGROUND: Iodine, an essential micronutrient, plays a critical role in normal growth and development, especially during the first two years of life. This systematic review and meta-analysis is among the first to evaluate breast-milk iodine concentrations and infant iodine status in countries characterized by iodine sufficiency or deficiency. METHODS: PubMed, Web of Science, Cochrane Library, Google Scholar, and other relevant databases, as well as reference lists of previous reviews, were searched for relevant studies published between 1986 and 2016...
January 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29322022/less-than-total-thyroidectomy-for-goiter-when-and-how
#18
REVIEW
Özer Makay
Benign goiter is the most common endocrine disease that requires surgery, especially in endemic areas suffering from iodine-deficiency. Recent European and American guidelines recommended total thyroidectomy for the surgical treatment of multinodular goiter. Total thyroidectomy has now become the technique of choice and is widely considered the most reliable approach in preventing recurrence. Nevertheless, total thyroidectomy carries a substantial risk in terms of hypoparathyroidism and the morbidity associated with injury to the inferior laryngeal nerve...
December 2017: Gland Surgery
https://www.readbyqxmd.com/read/29318297/iodine-catalyzed-transformation-of-aryl-substituted-alcohols-under-solvent-free-and-highly-concentrated-reaction-conditions
#19
Marjan Jereb, Dejan Vražič
Iodine-catalyzed transformations of alcohols under solvent-free reaction conditions (SFRC) and under highly concentrated reaction conditions (HCRC) in the presence of various solvents were studied in order to gain insight into the behavior of the reaction intermediates under these conditions. Dimerization, dehydration and substitution were the three types of transformations observed with benzylic alcohols. Dimerization and substitution reactions were predominant in the case of primary- and secondary alcohols, whereas dehydration prevailed in the case of tertiary alcohols...
December 2017: Acta Chimica Slovenica
https://www.readbyqxmd.com/read/29303778/veganism-as-a-cause-of-iodine-deficient-hypothyroidism
#20
Olga Yeliosof, Lawrence A Silverman
BACKGROUND: Iodine deficiency is the most common cause of acquired hypothyroidism worldwide. Although uncommon in the Western world, the incidence of iodine deficiency may be rising due to the increased use of restrictive diets. CASE PRESENTATION: We present a 23-month-old boy diagnosed with iodine deficiency hypothyroidism, induced by a vegan diet. CONCLUSIONS: This case highlights the risk for iodine deficiency in children on a vegan diet after discontinuation of breast/formula feeding that could lead to acquired hypothyroidism...
January 26, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
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