keyword
https://read.qxmd.com/read/38493431/evaluation-of-the-protective-and-therapeutic-effects-of-extra-virgin-olive-oil-rich-in-phenol-in-experimental-model-of-neonatal-necrotizing-enterocolitis-by-clinical-disease-score-%C3%A4-nflammation-apoptosis-and-oxidative-stress-markers
#1
JOURNAL ARTICLE
Mustafa Tuşat, Recep Eroz, Ferhan Bölükbaş, Erkan Özkan, Hüseyin Erdal
BACKGROUND AND AIM: Necrotizing Enterocolitis (NEC) is an inflammation-associated ischemic necrosis of the intestine. To investigate the effects of extra virgin olive oil (EVOO) on inflammation, oxidative stress, apoptosis, and histological changes in NEC-induced newborn rats. MATERIALS AND METHODS: 24 rats were randomly divided into three groups: control, NEC and NEC + EVOO. NEC induction was performed using hypoxia-hyperoxia, formula feeding, and cold stress...
March 17, 2024: Pediatric Surgery International
https://read.qxmd.com/read/38493321/nr3c2-microdeletions-an-underrecognized-cause-of-pseudohypoaldosteronism-type-1a-a-case-report-and-literature-review
#2
JOURNAL ARTICLE
Bobby L Boyanton, Yuri A Zarate, Brannon G Broadfoot, Thomas Kelly, Brendan D Crawford
OBJECTIVES: Pseudohypoaldosteronism type 1A (PHA1A) is caused by haploinsufficiency of the mineralocorticoid receptor (MR). Heterozygous small insertions/deletions, transitions, and/or transversions within NR3C2 comprise the majority (85%-90%) of pathogenic copy number variants. Structural chromosomal abnormalities, contiguous gene deletion syndromes, and microdeletions are infrequent. We describe a neonate with PHA1A due to a novel NR3C2 microdeletion involving exons 1-2. METHODS: Literature review identified 39 individuals with PHA1A due to NR3C2 microdeletions...
March 16, 2024: Laboratory Medicine
https://read.qxmd.com/read/38493272/automated-diagnosis-of-plus-disease-in-retinopathy-of-prematurity-using-quantification-of-vessels-characteristics
#3
JOURNAL ARTICLE
Sayed Mehran Sharafi, Nazanin Ebrahimiadib, Ramak Roohipourmoallai, Afsar Dastjani Farahani, Marjan Imani Fooladi, Elias Khalili Pour
The condition known as Plus disease is distinguished by atypical alterations in the retinal vasculature of neonates born prematurely. It has been demonstrated that the diagnosis of Plus disease is subjective and qualitative in nature. The utilization of quantitative methods and computer-based image analysis to enhance the objectivity of Plus disease diagnosis has been extensively established in the literature. This study presents the development of a computer-based image analysis method aimed at automatically distinguishing Plus images from non-Plus images...
March 16, 2024: Scientific Reports
https://read.qxmd.com/read/38493168/pregnancy-planning-and-neonatal-outcome-a-retrospective-cohort-study
#4
JOURNAL ARTICLE
Isa Reuterwall, Jenny Niemeyer Hultstrand, Alisa Carlander, Maria Jonsson, Tanja Tydén, Merit Kullinger
BACKGROUND: Unplanned pregnancy is common, and although some research indicates adverse outcomes for the neonate, such as death, low birth weight, and preterm birth, results are inconsistent. The purpose of the present study was to investigate associated neonatal outcomes of an unplanned pregnancy in a Swedish setting. METHODS: We conducted a retrospective cohort study in which data from 2953 women were retrieved from the Swedish Pregnancy Planning Study, covering ten Swedish counties from September 2012 through July 2013...
March 16, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38493094/awareness-and-healthcare-seeking-behavior-of-neonatal-danger-signs-and-predictor-variables-among-mothers-caregivers-in-four-developing-regional-state-of-ethiopia
#5
JOURNAL ARTICLE
Nagasa Dida, Lonsako Abute, Tariku Dejene, Tolasa Yadate, Temesgen Geleta, Rachana Sharma, Hnin Su Mon, Tesfaye Simireta, Hailemariam Addisu
INTRODUCTION: Mothers/caregivers should be aware of a newborn's danger signs and promptly seek medical attention. Hence, this study assessed mothers'/caregivers' awareness, healthcare seeking behaviors for neonatal danger signs and their determinants in the developing regional state of Ethiopia. METHODS: A community-based cross-sectional study was employed among mothers/caregivers of neonates in the developing regional state of Ethiopia. The sample was determined in collaboration with the Central Statistics Agency of Ethiopia...
March 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38493088/postnatal-care-and-acceptability-of-emollient-therapy-in-very-low-birthweight-infants-in-harare-zimbabwe-a-qualitative-analysis
#6
JOURNAL ARTICLE
Alexa Hui, Gwendoline Chimhini, Margaret Saungweme, Dorah Kaisi, Elisabeth Munetsi, Hilda A Mujuru, Gary L Darmstadt
BACKGROUND: Preterm birth (birth before 37 completed weeks of pregnancy) is the leading cause of neonatal and child under-five mortality globally, both of which are highest regionally in sub-Saharan Africa. The skin barrier plays a critical role in neonatal health and increasing evidence supports the use of topical emollient therapy to promote postnatal growth and reduce hospital-acquired infections in preterm infants. The World Health Organization (WHO) currently recommends emollient therapy in preterm or low birthweight infants globally but calls for further research on impacts of emollient use, especially in Africa...
March 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38493008/effects-of-the-covid-19-pandemic-on-gestational-diabetes-in-castilla-la-mancha-spain
#7
JOURNAL ARTICLE
Dulce M ª Calderón Vicente, Amparo Marco Martínez, Inés Gómez García, Rosa Quílez Toboso, Iván Quiroga López, Manolo Delgado Rey, Javier Gargallo Vaamonde, María Olmos Alemán, Raquel Miralles Moragrega, César Gonzalvo Díaz, Javier González López
SUBJECT-MATTER: To assess the effect of the 2019 coronavirus (COVID-19) pandemic on gestational diabetes (GDM). MATERIAL AND METHODS: In this retrospective, multicentre, non-interventional study carried out in Castilla-La Mancha, Spain, we compared 663 women with GDM exposed to the pandemic (pandemic group), with 622 women with GDM seen one year earlier (pre-pandemic group). The primary endpoint was a Large for Gestational Age (LGA) newborn as an indicator of poor GDM control...
March 15, 2024: Endocrinología, diabetes y nutrición
https://read.qxmd.com/read/38492916/the-future-of-neonatal-cerebral-oxygenation-monitoring-directions-after-the-safeboosc-iii-trial
#8
JOURNAL ARTICLE
Valerie Y Chock, Zachary A Vesoulis, Mohamed El-Dib, Topun Austin, Frank van Bel
No abstract text is available yet for this article.
March 14, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38492913/motivations-for-and-against-participation-in-neonatal-research-insights-from-interviews-of-diverse-parents-approached-for-neonatal-research-in-the-us
#9
JOURNAL ARTICLE
Elliott Mark Weiss, Pamela K Donohue, Susan H Wootton, Emily Stevens, Stephanie L Merhar, Mihai Puia-Dumitrescu, Amanda Mercer, Ellie Oslin, Kathryn M Porter, Benjamin S Wilfond
OBJECTIVE: To describe parents' motivations for and against participation in neonatal research, including the views of those who declined participation. STUDY DESIGN: We performed 44 semi-structured, qualitative interviews of parents approached for neonatal research. Here we describe their motivations for and against participation. RESULTS: Altruism was an important reason parents chose to participate. Some hoped participation in research would benefit their infant...
March 14, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38492743/-antenatal-care-for-fetuses-with-congenital-diaphragmatic-hernia
#10
JOURNAL ARTICLE
Charles Mégier, Alexandra Letourneau, Lina Bejjani, Meriem Macha Boumerzoug, Cécile Suffee, Van Huynh, Julien Saada, Grégoire Dumery, Alexandra Benachi
Congenital diaphragmatic hernia (CDH) can be diagnosed prenatally and its severity assessed by fetal imaging. The prognosis of a fetus with CDH is based on whether or not the hernia is isolated, the measurement of lung volume on ultrasound and MRI, and the position of the liver. The birth of a child with CDH should take place in a center adapted to the care of such children, and in accordance with the recommendations defined by the French National Diagnosis and Care Protocol. It has recently been demonstrated that for moderate and severe forms of CDH, tracheal occlusion using a balloon placed in utero by fetoscopy (FETO) increases survival until discharge from the neonatal unit, but at the cost of an increased risk of prematurity...
March 14, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38492741/-neurodevelopment-and-neuroprotection-in-young-children
#11
JOURNAL ARTICLE
Stéphane Marret, Alexandra Chadie, Jean-Baptiste Muller, Clément Chollat
In France, the most pessimistic estimates put the prevalence of neurodevelopmental disorders (NDD) at 15% of births. The two largest populations of newborns at highest risk of NDD are premature babies and babies born into siblings with one or more infants who already have an autism spectrum disorder or another NDD. The high prevalence of these disorders justifies a health promotion policy, centred on the child and his or her family. Prevention is based on the early identification of high-risk factors, by informing families and training pregnancy and early childhood professionals, and implementing perinatal prevention protocols for high-risk newborns (antenatal corticosteroid therapy and magnesium sulfate for women at risk of preterm delivery before 32 weeks, developmental care, therapeutic hypothermia for full-term infants with early neonatal encephalopathy presumed to be anoxic)...
March 14, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38492713/the-simultaneous-occurrence-of-gestational-diabetes-and-hypertensive-disorders-of-pregnancy-affects-fetal-growth-and-neonatal-morbidity
#12
JOURNAL ARTICLE
Chioma Onuoha, Carolin C M Schulte, Tanayott Thaweethai, Sarah Hsu, Deepti Pant, Kaitlyn E James, Sarbattama Sen, Anjali Kaimal, Camille E Powe
BACKGROUND: Gestational diabetes (GDM) is associated with an increased risk of hypertensive disorders of pregnancy (HDP), but there are limited data on fetal growth and neonatal outcomes when both conditions are present. OBJECTIVES: We evaluated the risk of abnormal fetal growth and neonatal morbidity in pregnancies with co-occurrence of GDM and HDP. STUDY DESIGN: In a retrospective study of 47,093 singleton pregnancies, we compared the incidence of appropriate for gestational age birthweight (AGA) in pregnancies affected by GDM alone, HDP alone, or both GDM and HDP (GDM/HDP) to that in pregnancies affected by neither disorder using generalized estimating equations (covariates: maternal age, nulliparity, BMI, insurance type, race, marital status and prenatal care site)...
March 14, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38492667/maternal-and-neonatal-outcomes-of-french-prospective-multicenter-cohort-study-covipreg-during-the-first-two-covid-19-waves
#13
JOURNAL ARTICLE
Alexandre J Vivanti, Camille Couffignal, Jeanne Sibiude, Anne-Gael Cordier, Vassilis Tsatsaris, Flore Rozenberg, Odile Launay, Alexandra Benachi, Daniele De Luca, Pierre-Yves Ancel, Estelle Marcault, Yves Ville, Julie Carrara, Dominique Luton, Marc Dommergues, Constance Borie, Gilles Kayem, Laurence Lecomte, Marianne Leruez-Ville, Claire Périllaud-Dubois, Valérie Biran, Pauline Manchon, Olivier Picone, Christelle Vauloup-Fellous
BACKGROUND: SARS-CoV-2 infection on pregnant women was the subject of many questions since the COVID-19 pandemic. METHODS: We aim to assess maternal and neonatal outcomes of SARS-CoV-2 infection contracted during 2nd and 3rd trimesters of pregnancy during the first two COVID-19 waves across a prospective French multicenter cohort study. Patients were included between April 2020 and January 2021 in 10 maternity hospitals in Paris area with two groups (i) pregnant women with a positive SARS-CoV-2 nasopharyngeal RT-PCR between [14WG; 37WG[(symptomatic infection), (ii) pregnant women with a negative serology (or equivocal) at delivery and without a positive SARS-CoV-2 nasopharyngeal RT-PCR at any time during pregnancy (G2 group) MAIN FINDINGS: 2410 pregnant women were included, of whom 310 had a positive SARS-CoV-2 nasopharyngeal RT-PCR and 217 between [14WG; 37WG[...
March 14, 2024: Journal of Gynecology Obstetrics and Human Reproduction
https://read.qxmd.com/read/38492551/on-punctate-white-matter-lesions-in-preterm-infants-is-ultrasound-diagnosis-feasible
#14
JOURNAL ARTICLE
Philippe Quétin, Nicolas Leboucq, Charlotte Boyer, Françoise Crozier, Philippe Delachartre, Marilyne Grinand, Philippe Masson, Olivier Claris
OBJECTIVES: To observe hyperechoic nodular or punctate white matter lesions (HNPL) in a population of preterm infants using routine cranial ultrasound (cUS), to describe the characteristics of HNPL, and to compare them with punctate white matter lesions (PWML) detected in magnetic resonance imaging (MRI). DESIGN: Retrospective observational single-center cohort study. SETTING: Level 2B neonatal unit in France. PATIENTS: 307 infants born <33 weeks gestation undergoing routine cUS with a total of 961 cUS performed...
March 1, 2024: European Journal of Paediatric Neurology: EJPN
https://read.qxmd.com/read/38492472/hla-g-isoforms-hla-c-allotype-and-their-expressions-differ-between-early-abortus-and-placenta-in-relation-to-spontaneous-abortions
#15
JOURNAL ARTICLE
Mayuri Bora, Sushmita Singha, Taruna Madan, Gitanjali Deka, Sumita Gogoi Hazarika, Shashi Baruah
INTRODUCTION: Spontaneous abortion (SAB) affects approximately 10% of clinically recognized pregnancies. Fetal trophobalst invasion and remodeling of maternal spiral arteries is reported to be dependent on crosstalk between HLA-C/HLA-G expressed on extra villous trophoblast (EVTs)and Killer cell Immunoglobin like receptors (KIRs) of decidual NK (dNK). Immune dysfunction in decidua contributes to early miscarriage. METHODOLOGY: The study used mother neonate paired cord blood and term placenta samples (n = 46), elective abortus (n = 17,gestational age = 10-12 weeks of pregnancy) and SAB abortus (n = 24, gestational age = 12-15 weeks of pregnancy) for HLA-G, KIR2D and HLA-C...
March 11, 2024: Placenta
https://read.qxmd.com/read/38492471/placentae-of-small-appropriately-grown-for-gestational-age-neonates-exhibit-sexually-dimorphic-transcriptomic-changes-representative-of-placental-insufficiency
#16
JOURNAL ARTICLE
Adam Ewing, Jessica L O'Callaghan, Sharon McCracken, Stacy Ellery, Martha Lappas, Olivia J Holland, Anthony Perkins, Zarqa Saif, Vicki L Clifton
INTRODUCTION: Previous studies have reported that neonates less than the 25th BWC especially if they were male, were more likely to be associated with birth complications suggesting small neonates often identified as appropriately grown are at risk of adverse outcomes. We have questioned whether smaller neonates not typically categorized as "small for gestational age" may not reach their genetically determined growth due to placental insufficiency. METHODS: RNA-Seq was performed on the Illumina NovaSeq 600 using term placentae from neonates that were less than the 10th birthweight centile (BWC) (n = 39), between the 10th and the 30th BWC (n = 15) or greater than the 30th BWC (n = 23)...
February 23, 2024: Placenta
https://read.qxmd.com/read/38492414/relationships-between-preterm-medical-factors-and-feeding-behaviors-at-term-equivalent-age
#17
JOURNAL ARTICLE
Carolyn Ibrahim, Molly Grabill, Joan Smith, Roberta Pineda
AIM: To identify relationships between early medical factors and preterm infant feeding behaviors at term-equivalent age. METHODS: Forty-three very preterm infants born ≤32 weeks gestation had standardized feeding assessments using the Neonatal Eating Outcome Assessment at term-equivalent age (36-42 weeks postmenstrual age). Medical factors were collected and analyses were run to determine if associations between different medical factors and feeding performance exist...
February 28, 2024: Early Human Development
https://read.qxmd.com/read/38492127/updates-to-the-melbourne-children-s-regional-infant-brain-software-package-m-crib-s
#18
JOURNAL ARTICLE
Chris L Adamson, Bonnie Alexander, Claire E Kelly, Gareth Ball, Richard Beare, Jeanie L Y Cheong, Alicia J Spittle, Lex W Doyle, Peter J Anderson, Marc L Seal, Deanne K Thompson
The delineation of cortical areas on magnetic resonance images (MRI) is important for understanding the complexities of the developing human brain. The previous version of the Melbourne Children's Regional Infant Brain (M-CRIB-S) (Adamson et al. Scientific Reports, 10(1), 10, 2020) is a software package that performs whole-brain segmentation, cortical surface extraction and parcellation of the neonatal brain. Available cortical parcellation schemes in the M-CRIB-S are the adult-compatible 34- and 31-region per hemisphere Desikan-Killiany (DK) and Desikan-Killiany-Tourville (DKT), respectively...
March 16, 2024: Neuroinformatics
https://read.qxmd.com/read/38492082/pregnancy-in-myasthenia-gravis-a-retrospective-analysis-of-maternal-and-neonatal-outcome-from-a-large-tertiary-care-centre-in-germany
#19
JOURNAL ARTICLE
Jakob Draxler, Andreas Meisel, Frauke Stascheit, Maike Stein, Lea Gerischer, Philipp Mergenthaler, Meret Herdick, Paolo Doksani, Sophie Lehnerer, Stefan Verlohren, Sarah Hoffmann
PURPOSE: Myasthenia gravis (MG) is a rare, potentially life-threatening autoimmune disease with fluctuating muscle weakness frequently affecting women of childbearing age. MG can affect maternal as well as neonatal outcome with risk of worsening of myasthenic symptoms in the mothers and risk of transient neonatal myasthenia gravis (TNMG) and arthrogryposis multiplex congenita (AMC) or foetal acetylcholine receptor antibody-associated disorders (FARAD) in the neonates. METHODS: Retrospective analysis of maternal and neonatal outcome in a cohort of pregnant MG patients treated at a tertiary care centre in Germany...
March 16, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38492032/ototoxic-and-nephrotoxic-drugs-in-neonatal-intensive-care-units-results-of-a-spanish-and-italian-survey
#20
JOURNAL ARTICLE
Cristina Arribas, Nunzia Decembrino, Genny Raffaeli, Ilaria Amodeo, Juan Luis González-Caballero, Mónica Riaza, Roberto Ortiz-Movilla, Luca Massenzi, Camilla Gizzi, Gabriella Araimo, Donatella Cattarelli, Salvatore Aversa, Stefano Martinelli, Simonetta Frezza, Luigi Orfeo, Fabio Mosca, Giacomo Cavallaro, Felipe Garrido
UNLABELLED: Neonates face heightened susceptibility to drug toxicity, often exposed to off-label medications with dosages extrapolated from adult or pediatric studies. Premature infants in Neonatal Intensive Care Units (NICUs) are particularly at risk due to underdeveloped pharmacokinetics and exposure to multiple drugs. The study aimed to survey commonly used medications with a higher risk of ototoxicity and nephrotoxicity in Spanish and Italian neonatal units. A prospective cross-sectional study was conducted in Italian and Spanish neonatal units using a web-based survey with 43 questions...
March 16, 2024: European Journal of Pediatrics
keyword
keyword
849
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.