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https://www.readbyqxmd.com/read/29776810/congenital-heart-disease-in-adults-assessmentof-functional-capacity-using-cardiopulmonary-exercise-testing
#1
Sílvia Aguiar Rosa, Ana Agapito, Rui M Soares, Lídia Sousa, José Alberto Oliveira, Ana Abreu, Ana Sofia Silva, Sandra Alves, Helena Aidos, Fátima F Pinto, Rui Cruz Ferreira
AIM: The aim of the study was to compare functional capacity in different types of congenital heart disease (CHD), as assessed by cardiopulmonary exercise testing (CPET). METHODS: A retrospective analysis was performed of adult patients with CHD who had undergone CPET in a single tertiary center. Diagnoses were divided into repaired tetralogy of Fallot, transposition of the great arteries (TGA) after Senning or Mustard procedures or congenitally corrected TGA, complex defects, shunts, left heart valve disease and right ventricular outflow tract obstruction...
May 15, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29761312/recovery-of-upper-body-muscle-power-after-short-intensive-exercise-comparing-boys-and-men
#2
Yitzhak Weinstein, Omri Inbar, Ron Mor-Unikovski, Anthony Luder, Gal Dubnov-Raz
PURPOSE: Boys' lower-body muscle power generation (PO) recovers faster than men's following intensive exercise. The purpose of this study was to examine whether boys differ from adult men in recovering from upper-body muscle power generation following intensive exercise. METHODS: Fifteen prepubertal boys (M ± SD age 10.6 ± 1.0 years) and 13 men (31.1 ± 5.0 years) performed two upper-body Wingate Anaerobic Tests (WAnT), separated by either 2-min or 10-min recovery intervals...
May 14, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29757824/improvements-in-key-cardiopulmonary-exercise-testing-variables-following-cardiac-rehabilitation-in-patients-with-coronary-artery-disease
#3
Dejana Popovic, Nikhil Kumar, Sundeep Chaudhry, Akshay Bagai, Ross Arena, Naresh Kumar
PURPOSE: Improvements in cardiorespiratory fitness (VO2peak) post-cardiac rehabilitation (post-CR) are used to gauge therapeutic efficacy. The aim of the present study was to assess the effect of supervised CR on other cardiopulmonary exercise testing (CPX) variables, specifically those that reflect ventilatory efficiency and VO2 changes in relation to changes in work rate (WR). METHODS: Patients (n = 142; mean age 63 ± 9 y; 23% female) with coronary artery disease (CAD) participated in supervised CR for 3 to 6 mo completing 60 ± 17 sessions (range: 32-96 sessions), with intensity derived from the baseline CPX...
May 11, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29740332/metabolic-and-fatigue-profiles-are-comparable-between-prepubertal-children-and-well-trained-adult-endurance-athletes
#4
Anthony Birat, Pierre Bourdier, Enzo Piponnier, Anthony J Blazevich, Hugo Maciejewski, Pascale Duché, Sébastien Ratel
The aim of this study was to determine whether prepubertal children are metabolically comparable to well-trained adult endurance athletes and if this translates into similar fatigue rates during high-intensity exercise in both populations. On two different occasions, 12 prepubertal boys (10.5 ± 1.1 y), 12 untrained men (21.2 ± 1.5 y), and 13 endurance male athletes (21.5 ± 2.7 y) completed an incremental test to determine the power output at VO2max (PVO2max ) and a Wingate test to evaluate the maximal anaerobic power (Pmax ) and relative decrement in power output (i...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29738892/effect-of-short-term-cold-water-immersion-on-muscle-pain-sensitivity-in-elite-track-cyclists
#5
Sebastian Klich, Igor Krymski, Kamil Michalik, Adam Kawczyński
OBJECTIVE: To determine the effect of short-term cold-water immersion (CWI) on muscle pain sensitivity after maximal anaerobic power training in track cyclists. DESIGN: Repeated measures. SETTING: University Laboratory. PARTICIPANTS: 12 elite sprint track cyclists (age 24,75 ± 4,23 years). MAIN OUTCOME MEASURES: PPT measurements were made on dominant lower extremity (right) in 20 reference points, including anterior thigh muscles, posterior thigh muscles and posterior cuff muscles...
May 1, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29738374/effect-of-interleukin-1-blockade-on-left-ventricular-systolic-performance-and-work-a-post-hoc-pooled-analysis-of-two-clinical-trials
#6
Leo F Buckley, Salvatore Carbone, Cory R Trankle, Justin M Canada, Claudia Oddi Erdle, Jessica A Regan, Michele M Viscusi, Dinesh Kadariya, Hayley Billingsley, Ross Arena, Antonio Abbate, Benjamin W Van Tassell
BACKGROUND: Interleukin-1 (IL-1) blockade appears to improve anaerobic exercise in patients with systolic heart failure through improved left ventricular systolic performance. However, it is unclear whether IL-1 blockade affects left ventricular systolic performance. METHODS: We pooled data from two clinical trials of patients with systolic heart failure who were randomized to IL-1 blockade or placebo. We estimated changes in left ventricular systolic performance (left ventricular ejection fraction [LVEF] and end-systolic elastance [LVEes]) and pressure-volume area, a surrogate of oxygen consumption, after 14 days of treatment...
April 30, 2018: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/29730785/may-the-force-be-with-you-why-resistance-training-is-essential-for-subjects-with-type-2-diabetes-mellitus-without-complications
#7
REVIEW
Roberto Codella, Marta Ialacqua, Ileana Terruzzi, Livio Luzi
Physical activity, together with diet and pharmacological therapy, represents one of the three cornerstones in type 2 diabetes mellitus treatment and care. The therapeutic appeal of regular physical activity stems from: (i) its non-pharmacological nature; (ii) its beneficial effects on the metabolic risk factors associated with diabetes complications; (iii) its low costs. Evidence accumulated in the last years suggests that aerobic training-endurance training-constitutes a safe modality of intervention, achievable, and effective in diabetes treatment, whenever it is not limited by comorbidities...
May 5, 2018: Endocrine
https://www.readbyqxmd.com/read/29727012/reliability-of-repeated-arm-crank-cardiopulmonary-exercise-tests-in-patients-with-small-abdominal-aortic-aneurysm
#8
J W Durrand, K Wagstaff, A Kasim, L Cawthorn, G R Danjoux, E Kothmann
Arm-crank ergometry may be useful in patients unable to pedal, for instance due to peripheral arterial disease. Twenty participants with small abdominal aortic aneurysm undertook two serial arm-crank tests and then a pedal test, four of whom had indeterminate anaerobic thresholds, precluding analysis. The mean (SD) peak arm and leg oxygen consumptions in 16 participants were 13.71 (2.62) ml.kg-1 .min-1 and 16.82 (4.44) ml.kg-1 .min-1 , with mean (SD) individual differences of 3.11 (2.48) ml.kg-1 .min-1 , p = 0...
May 4, 2018: Anaesthesia
https://www.readbyqxmd.com/read/29721434/physiological-parameter-values-in-greyhounds-before-and-after-high-intensity-exercise
#9
Francisco Javier Pellegrino, Analía Risso, Pablo G Vaquero, Yanina A Corrada
Dog sports competitions have greatly expanded. The availability of reference values for each type of activity could help assess fitness accurately. Heart rate (HR), blood lactate (BL) and rectal temperature (RT) are relevant physiological parameters to determine the dogs response to effort. Previous studies in greyhounds have reported the effect of high-intensity exercise on many physiological parameters immediately after completing different racing distances and recovery times. However, there are no studies concerning physiological changes over shorter racing distances...
2018: Open Veterinary Journal
https://www.readbyqxmd.com/read/29720949/active-recovery-after-high-intensity-interval-training-does-not-attenuate-training-adaptation
#10
Thimo Wiewelhove, Christoph Schneider, Alina Schmidt, Alexander Döweling, Tim Meyer, Michael Kellmann, Mark Pfeiffer, Alexander Ferrauti
Objective: High-intensity interval training (HIIT) can be extremely demanding and can consequently produce high blood lactate levels. Previous studies have shown that lactate is a potent metabolic stimulus, which is important for adaptation. Active recovery (ACT) after intensive exercise, however, enhances blood lactate removal in comparison with passive recovery (PAS) and, consequently, may attenuate endurance performance improvements. Therefore, the aim of this study was to examine the influence of regular ACT on training adaptations during a HIIT mesocycle...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29719514/longer-work-rest-intervals-during-high-intensity-interval-training-hiit-lead-to-elevated-levels-of-mir-222-and-mir-29c
#11
Boris Schmitz, Florian Rolfes, Katrin Schelleckes, Mirja Mewes, Lothar Thorwesten, Michael Krüger, Andreas Klose, Stefan-Martin Brand
Aim: MicroRNA-222 (miR-222) and miR-29c have been identified as important modulators of cardiac growth and may protect against pathological cardiac remodeling. miR-222 and -29c may thus serve as functional biomarkers for exercise-induced cardiac adaptations. This investigation compared the effect of two workload-matched high-intensity interval training (HIIT) protocols with different recovery periods on miR-222 and -29c levels. Methods: Sixty-three moderately trained females and males (22.0 ± 1.7 years) fulfilled the eligibility criteria and were randomized into two HIIT groups using sex and exercise capacity...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29719513/adaptive-changes-after-2-weeks-of-10-s-sprint-interval-training-with-various-recovery-times
#12
Robert A Olek, Sylwester Kujach, Ewa Ziemann, Wieslaw Ziolkowski, Piotr Waz, Radoslaw Laskowski
Purpose: The aim of this study was to compare the effect of applying two different rest recovery times in a 10-s sprint interval training session on aerobic and anaerobic capacities as well as skeletal muscle enzyme activities. Methods: Fourteen physically active but not highly trained male subjects (mean maximal oxygen uptake 50.5 ± 1.0 mlO2 ·kg-1 ·min-1 ) participated in the study. The training protocol involved a series of 10-s sprints separated by either 1-min (SIT10:1) or 4-min (SIT10:4) of recovery...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29719466/effect-of-high-dose-ginsenoside-complex-ug0712-supplementation-on-physical-performance-of-healthy-adults-during-a-12-week-supervised-exercise-program-a-randomized-placebo-controlled-clinical-trial
#13
Eon Sook Lee, Yun Jun Yang, Jun Hyung Lee, Yeong Sook Yoon
Background: Ginseng has been used as an ergogenic agent, although evidence for its effectiveness is weak. A randomized, double-blind, placebo-controlled clinical trial was conducted to evaluate the effect of a ginsenoside complex (UG0712) on changes in exercise performance. Methods: Sedentary individuals ( n   =  117) were randomly assigned into one of three groups: low-dose ginsenoside supplementation (100 mg/d, n   =  39), high-dose ginsenoside supplementation (500 mg/d, n   =  39), or a placebo group (500 mg/d, n   =  39)...
April 2018: Journal of Ginseng Research
https://www.readbyqxmd.com/read/29698982/a-fast-track-to-hypoalgesia-the-anaerobic-exercise-effect-on-pain-sensitivity
#14
Gil Samuelly-Leichtag, Einat Kodesh, Yoav Meckel, Irit Weissman-Fogel
Maximal anaerobic exercise, is a short high intensity effort, involves activation of the hypothalamus-pituitary-adrenal axis, and may suggest hypoalgesic effects. In addition, this exercise-induced muscle pain may contribute to hypoalgesia via the pain inhibits pain phenomenon, which is related to the diffuse noxious inhibitory control (DNIC) mechanism. We aimed to investigate whether: 1) a single bout of 30 s maximal anaerobic exercise has an analgesic effect on experimental pain sensitivity; 2) DNIC is the underlying mechanism of anaerobic exercise-induced hypoalgesia (EIH)...
April 26, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29692190/routine-pre-and-post-neoadjuvant-chemotherapy-fitness-testing-is-not-indicated-for-oesophagogastric-cancer-surgery
#15
R J Drummond, D Vass, H Wadhawan, C F Craig, C K MacKay, G M Fullarton, M J Forshaw
Introduction There is a known correlation between anaerobic threshold (AT) during cardiopulmonary exercise testing and development of cardiopulmonary complications in high-risk patients undergoing oesophagogastric cancer surgery. This study aimed to assess the value of routine retesting following neoadjuvant chemotherapy. Methods Patients undergoing neoadjuvant chemotherapy with subsequent oesophagogastric cancer surgery with pre- and post-neoadjuvant chemotherapy cardiopulmonary exercise data were identified from a prospectively maintained database...
April 25, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29683925/short-term-8-weeks-high-intensity-interval-training-in-diseased-cohorts
#16
James E M Blackwell, Brett Doleman, Philip J J Herrod, Samuel Ricketts, Bethan E Phillips, Jonathan N Lund, John P Williams
BACKGROUND & AIM: Exercise training regimes can lead to improvements in measures of cardiorespiratory fitness (CRF), improved general health, and reduced morbidity and overall mortality risk. High intensity interval training (HIIT) offers a time-efficient approach to improve CRF in healthy individuals, but the relative benefits of HIIT compared to traditional training methods are unknown in across different disease cohorts. METHODS: This systematic review and meta-analysis compares CRF gains in randomised controlled trials of short-term (<8 weeks) HIIT vs...
April 21, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29666705/the-role-of-moderate-aerobic-exercise-as-determined-by-cardiopulmonary-exercise-testing-in-als
#17
Anna Caroline Marques Braga, Anabela Pinto, Susana Pinto, Mamede de Carvalho
Introduction: The efficacy of cardiopulmonary exercise testing (CPET) to determining exercise intensity has not been established in Amyotrophic Lateral Sclerosis (ALS). We studied this intervention. Methods: We included 48 ALS patients randomized in 2 groups: G1 ( n = 24), exercise intensity leveled by CPET; G2 ( n = 24), standard care limited by fatigue, during 6 months. ALS functional scale (ALSFRS-R) and forced vital capacity (FVC) were performed every 3 months; CPET was done at admission ( T 1) and 6 months later ( T 2)...
2018: Neurology Research International
https://www.readbyqxmd.com/read/29650336/acute-physiological-responses-to-low-intensity-blood-flow-restriction-cycling
#18
H J Thomas, B R Scott, J J Peiffer
OBJECTIVES: Blood flow restriction (BFR) during interval cycling may stimulate aerobic and anaerobic adaptations. However, acute physiological responses to BFR interval cycling have not been extensively investigated. DESIGN: Eighteen males completed low-intensity (LI), low-intensity with BFR (LIBFR ) and high-intensity (HI) interval cycling sessions in randomised and counterbalanced order. These included a standardised warm-up and three two-min intervals interspersed with two-min recovery...
April 9, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29644702/influence-of-group-iii-iv-muscle-afferents-on-small-muscle-mass-exercise-performance-a-bioenergetics-perspective
#19
Ryan M Broxterman, Thomas J Hureau, Gwenael Layec, David E Morgan, Amber D Bledsoe, Jacob E Jessop, Markus Amann, Russell S Richardson
The direct influence of group III/IV muscle afferents on exercise performance remains equivocal. Therefore, all-out intermittent isometric single-leg knee-extensor exercise and phosphorous magnetic resonance spectroscopy (31 P-MRS) were utilized to provide a high time resolution assessment of exercise performance and skeletal muscle bioenergetics in control conditions (CTRL) and with the attenuation of group III/IV muscle afferent feedback via lumbar intrathecal fentanyl (FENT). In both conditions, seven recreationally active men performed 60 maximal voluntary quadriceps contractions (MVC; 3 s contraction, 2 s relaxation), while knee-extensor force and 31 P-MRS were assessed during each MVC...
April 12, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29623546/exercise-rehabilitation-in-ventricular-assist-device-recipients-a-meta-analysis-of-effects-on-physiological-and-clinical-outcomes
#20
REVIEW
Liza Grosman-Rimon, Spencer D Lalonde, Nina Sieh, Maureen Pakosh, Vivek Rao, Paul Oh, Sherry L Grace
Exercise rehabilitation in heart failure patients has been shown to improve quality of life (QoL) and survival. It is also recommended in clinical practice guidelines for ventricular assist device (VAD) recipients. However, there have only been two meta-analyses on the effects of exercise rehabilitation in VAD patients, on only two outcomes. The objective of the review was to quantitatively evaluate the effect of exercise rehabilitation in VAD recipients on functional capacity, exercise physiology parameters, chronotropic responses, inflammatory biomarkers and neurohormones, heart structure and function, and clinical outcomes...
April 6, 2018: Heart Failure Reviews
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