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https://www.readbyqxmd.com/read/29770287/ultra-early-optic-nerve-decompression-for-the-resection-of-anterior-clinoidal-meningioma
#1
Soichi Oya, Toru Matsui
Improvement in vision is one of the main goals of surgery for anterior clinoidal meningiomas with visual deficits. Early optic nerve decompression surgery has been advocated in previous studies to achieve the best visual outcome. Through this video, the authors describe their surgical techniques to decompress the optic nerve at the very early stage of surgery. A 35-year-old patient presented with subjective blurry vision in the right eye over the last 8 months. Magnetic resonance images showed a 3.2-cm meningioma arising at the right anterior clinoid...
February 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29768927/ultrasonographic-optic-nerve-sheath-diameter-to-detect-increased-intracranial-pressure-in-adults-a-meta-analysis
#2
Sung-Eun Kim, Eun Pyo Hong, Heung Cheol Kim, Si Un Lee, Jin Pyeong Jeon
Background The optimal optic nerve sheath diameter (ONSD) cut-off for identifying increased intracranial pressure (IICP) remains unclear in adult patients. Purpose To validate the diagnostic accuracy of ultrasonographic (US) ONSD > 5.0 mm as a cut-off for detecting IICP by computed tomographic (CT) through a meta-analysis. Material and Methods A systemic literature review was performed of online databases from January 1990 to September 2017. A bivariate random-effects model was used to estimate pooled sensitivity, specificity, and diagnostic odds ratio (DOR) with 95% confidence intervals (CIs)...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29767632/reply-to-comment-on-invasive-and-noninvasive-means-of-measuring-intracranial-pressure-a-review
#3
Xuan Zhang, Joshua E Medow, Bermans J Iskandar, Fa Wang, Mehdi Shokoueinejad, Joyce Koueik, John G Webster
In their comments, Drs. De Bernardo and Rosa stated that our paper was missing several references
 related to optic nerve sheath diameter ONSD assessments. Specifically, they state that we neglected to
 mention that ultrasound has been used since the 1970s, that we did not emphasize the role of
 Standardized A scans, and they reference some of their publications in which they emphasize the
 importance of these scans in diagnosing optic nerve lesions and benign intracranial hypertension...
May 16, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29765952/malignant-orbital-meningioma-originating-from-the-frontal-lobe
#4
Giancarlo A Garcia, Andrew E Choy, Anton N Hasso, Don S Minckler
Purpose of the Study: Orbital meningiomas are typically benign tumors, most commonly originating from the dura of the sphenoid wing or the optic nerve sheath. Procedures: We describe an unusual case of a malignant meningioma originating from the frontal lobe that ultimately produced orbital and distant metastases. Results and Conclusions: Orbital invasion by the meningioma was preceded by multiple incomplete resections, which may have facilitated access to the orbit...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29763714/optic-nerve-sheath-diameter-measured-using-early-unenhanced-brain-computed-tomography-shows-no-correlation-with-neurological-outcomes-in-patients-undergoing-targeted-temperature-management-after-cardiac-arrest
#5
Dong Hoon Lee, Sun Hwa Lee, Je Hyeok Oh, In Soo Cho, Young Hwan Lee, Chul Han, Wook Jin Choi, You Dong Sohn
AIM: Previous studies indicated that the optic nerve sheath diameter (ONSD) measured using brain computed tomography (CT) is a prognostic factor for poor neurological outcome after cardiac arrest. However, these studies were retrospective or included a small sample size. We performed a prospective multi-centre observational study to investigate the correlation between the ONSD on early brain CT and neurological outcomes in patients undergoing targeted temperature management (TTM). METHODS: This study used data from the Korean Hypothermia Network prospective registry between November 2015 and October 2016...
May 12, 2018: Resuscitation
https://www.readbyqxmd.com/read/29756721/-pseudotumor-cerebri-associated-with-hypovitaminosis-a-b6-and-d-about-two-cases
#6
Ana M Silva, José Méndez, Marisol Toma, Alejandra González, Federico Bois
Idiopathic endocranial hypertension is infrequently associated with hypovitaminosis A and D. The case of an 8-year-old female with 24-hour blurred vision and bilateral papilledema is presented. Nuclear magnetic resonance was normal. Opening pressure of cerebrospinal fluid: 260 mmH2O. She presented vitamin A and D deficiency and started replacement therapy. The second case corresponds to a 12-year-old male with fever and odynophagia of 3 days. History of glomerulonephritis and overweight. He had bipalpebral edema and papilledema...
June 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29746818/lymphatic-markers-in-the-human-optic-nerve
#7
A Trost, C Runge, D Bruckner, A Kaser-Eichberger, B Bogner, C Strohmaier, H A Reitsamer, F Schroedl
Tissues of the central nervous system (CNS), including the optic nerve (ON), are considered a-lymphatic. However, lymphatic structures have been described in the dura mater of human ON sheaths. Since it is known that lymphatic markers are also expressed by single non-lymphatic cells, these results need confirmation according to the consensus statement for the use of lymphatic markers in ophthalmologic research. The aim of this study was to screen for the presence of lymphatic structures in the adult human ON using a combination of four lymphatic markers...
May 7, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29740393/comparison-of-ocular-ultrasonography-and-magnetic-resonance-imaging-for-detection-of-increased-intracranial-pressure
#8
David F Patterson, Mai-Lan Ho, Jacqueline A Leavitt, Nathan J Smischney, Sara E Hocker, Eelco F Wijdicks, David O Hodge, John Jing-Wei Chen
Background/aims: To evaluate and compare the performance of ocular ultrasonography (US) and magnetic resonance imaging (MRI) for detecting increased intracranial pressure (ICP) in patients with idiopathic intracranial hypertension (IIH). Methods: Twenty-two patients with papilledema from IIH and 22 with pseudopapilledema were prospectively recruited based on funduscopic and clinical findings. Measurements of optic nerve sheath diameters (ONSDs) 3 mm behind the inner sclera were performed on B-scan US and axial T2-weighted MRI examinations...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29725955/analysis-of-cerebral-blood-flow-and-intracranial-hypertension-in-critical-patients-with-non-hepatic-hyperammonemia
#9
Alexandre Sanches Larangeira, Marcos Toshiyuki Tanita, Marcos Antonio Dias, Olavo Franco Ferreira Filho, Vinicius Daher Alvares Delfino, Lucienne Tibery Queiroz Cardoso, Cintia Magalhães Carvalho Grion
Hyperammonemia in adults is generally associated with cerebral edema, decreased cerebral metabolism, and increased cerebral blood flow. The aim of this study was to evaluate the association between non-hepatic hyperammonemia and intracranial hypertension assessed by Doppler flowmetry and measurement of the optic nerve sheath. A prospective cohort study in critically ill patients hospitalized in intensive care units of a University Hospital between March 2015 and February 2016. Clinical data and severity scores were collected and the Glasgow coma scale was recorded...
May 3, 2018: Metabolic Brain Disease
https://www.readbyqxmd.com/read/29725178/bedside-ultrasonography-as-an-alternative-to-computed-tomography-scan-for-the-measurement-of-optic-nerve-sheath-diameter
#10
Uday Yanamandra, Amul Gupta, Sushma Yanamandra, Subrat Kumar Das, Sagarika Patyal, Velu Nair
Background: Optic nerve sheath diameter (ONSD) as measured by optic nerve sheath ultrasonography (ONSU) is used as a surrogate marker of intracranial pressure (ICP), especially in resource-limited settings. There is a growing interest in the use of ONSU in emergency and high-altitude setups. Notwithstanding multiple studies done on this subject, there is a paucity of data regarding standardization of techniques and comparison of ONSU with computed tomography (CT). Materials and Methods: Thirty-five patients with a diagnosis of high-altitude cerebral edema were enrolled in the study...
April 2018: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/29713911/early-intervention-using-high-precision-radiotherapy-preserved-visual-function-for-five-consecutive-patients-with-optic-nerve-sheath-meningioma
#11
Toshihiko Inoue, Osamu Mimura, Norihisa Masai, Atuyuki Ohashi, Koji Ikenaga, Yoshishige Okuno, Iku Nishiguchi, Ryoongjin Oh
BACKGROUND: There has been a paradigm shift in the treatment for optic nerve sheath meningioma (ONSM) from surgery to fractionated stereotactic radiotherapy (FSRT) in other countries. However, FSRT has seldom been performed in Japan. The purpose of this retrospective study is to reconfirm the effectiveness of early intervention with precision radiotherapy for ONSM reported in our previous study. METHODS: Five consecutive patients with ONSM were retrospectively analyzed...
April 30, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29695767/cutaneous-neurofibromas-in-the-genomics-era-current-understanding-and-open-questions
#12
REVIEW
Robert J Allaway, Sara J C Gosline, Salvatore La Rosa, Pamela Knight, Annette Bakker, Justin Guinney, Lu Q Le
Cutaneous neurofibromas (cNF) are a nearly ubiquitous symptom of neurofibromatosis type 1 (NF1), a disorder with a broad phenotypic spectrum caused by germline mutation of the neurofibromatosis type 1 tumour suppressor gene (NF1). Symptoms of NF1 can include learning disabilities, bone abnormalities and predisposition to tumours such as cNFs, plexiform neurofibromas, malignant peripheral nerve sheath tumours and optic nerve tumours. There are no therapies currently approved for cNFs aside from elective surgery, and the molecular aetiology of cNF remains relatively uncharacterised...
April 26, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29681099/2016-children-s-tumor-foundation-conference-on-neurofibromatosis-type-1-neurofibromatosis-type-2-and-schwannomatosis
#13
Michael J Fisher, Allan J Belzberg, Peter de Blank, Thomas De Raedt, Florent Elefteriou, Rosalie E Ferner, Marco Giovannini, Gordon J Harris, Michel Kalamarides, Matthias A Karajannis, AeRang Kim, Conxi Lázaro, Lu Q Le, Wei Li, Robert Listernick, Staci Martin, Helen Morrison, Eric Pasmant, Nancy Ratner, Elisabeth Schorry, Nicole J Ullrich, David Viskochil, Brian Weiss, Brigitte C Widemann, Yuan Zhu, Annette Bakker, Eduard Serra
Organized and hosted by the Children's Tumor Foundation (CTF), the Neurofibromatosis (NF) conference is the premier annual gathering for clinicians and researchers interested in neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and schwannomatosis (SWN). The 2016 edition constituted a blend of clinical and basic aspects of NF research that helped in clarifying different advances in the field. The incorporation of next generation sequencing is changing the way genetic diagnostics is performed for NF and related disorders, providing solutions to problems like genetic heterogeneity, overlapping clinical manifestations, or the presence of mosaicism...
May 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29657371/comparison-of-optic-nerve-sheath-diameter-between-both-eyes-a-bedside-ultrasonography-approach
#14
Uday Yanamandra, Amul Gupta, Srinivasa A Bhattachar, Sushma Yanamandra, Subrat K Das, Sagarika Patyal, Rajan Grewal, Velu Nair
Context: Optic nerve sheath diameter (ONSD) has long been accepted as a reliable proxy of intracranial pressure especially in critical care and bedside settings. The present consensus is to measure ONSD in both eyes and take average value, which is cumbersome and a potential cause of discomfort to the patient. Aim: We aim to compare the values of ONSD of the right and left eye in a random sample as measured by bedside ocular ultrasonography (USG) in Indian adults...
March 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29651628/intracranial-and-intraocular-pressure-at-the-lamina-cribrosa-gradient-effects
#15
REVIEW
Gauti Jóhannesson, Anders Eklund, Christina Lindén
PURPOSE OF REVIEW: A pressure difference between the intraocular and intracranial compartments at the site of the lamina cribrosa has been hypothesized to have a pathophysiological role in several optic nerve head diseases. This paper reviews the current literature on the translamina cribrosa pressure difference (TLCPD), the associated pressure gradient, and its potential pathophysiological role, as well as the methodology to assess TLCPD. RECENT FINDINGS: For normal-tension glaucoma (NTG), initial studies indicated low intracranial pressure (ICP) while recent findings indicate that a reduced ICP is not mandatory...
April 12, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29644809/optic-nerve-sheath-meningioma-preliminary-analysis-of-the-role-of-radiation-therapy
#16
Jun Jin, Jin Deok Joo, Jung Ho Han, Hee Kyung Yang, Jeong Min Hwang, Yi Jun Kim, In Ah Kim, Chae Yong Kim
BACKGROUND: The purpose of this study was to evaluate the treatment outcome of our optic nerve sheath meningioma (ONSM) case series in terms of preventing tumor growth and preserving vision in ONSM patients. METHODS: Between July 2003 and March 2015, 1,398 patients with intracranial meningioma were diagnosed at Seoul National University Bundang Hospital. Among them, only 13 patients (0.93%) were diagnosed with ONSM and enrolled in the present study. Tumor volume changes of ONSM patients and their visual acuity were evaluated before and after treatments...
April 2, 2018: Brain Tumor Research and Treatment
https://www.readbyqxmd.com/read/29628552/ultrasonographic-optic-nerve-sheath-diameter-as-a-surrogate-measure-of-raised-intracranial-pressure-in-severe-pregnancy-induced-hypertension-patients
#17
Shiv Kumar Singh, Kiran Bhatia
Context: It is a well-known fact that severe pregnancy-induced hypertension (PIH) can be disastrous at times as it can cause a lot of complications to both pregnant women and her baby. Hence, it is always desirable to know the extent of severity by a real-time and easily accessible modality like ultrasound. Aims: The aim of the study was to evaluate the incidence of raised intracranial pressure (ICP) in severe preeclampsia and eclampsia patients using ocular ultrasonography with optic nerve sheath diameter (ONSD) measurement...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29594060/prevalence-of-radiological-signs-of-dysthyroid-optic-neuropathy-in-magnetic-resonance-imaging-in-patients-with-active-moderate-to-severe-and-very-severe-graves-orbitopathy
#18
Beata Rutkowska-Hinc, Edyta Maj, Anna Jabłońska, Justyna Milczarek-Banach, Tomasz Bednarczuk, Piotr Miśkiewicz
Background: Differentiating between dysthyroid optic neuropathy (DON), which requires urgent therapy to prevent blindness, and moderate-to-severe Graves orbitopathy (GO) remains challenging. There is no pathognomonic feature of DON in either ophthalmological or radiological examinations. Objectives: Our aim was to investigate the prevalence of radiological signs of DON in magnetic resonance imaging (MRI) in patients with moderate-to-severe and very severe GO. Methods: Two researchers reassessed MRI scans of 23 consecutive patients (46 eyes) with active, moderate-to-severe GO and 14 patients (23 eyes) with very severe GO...
March 2018: European Thyroid Journal
https://www.readbyqxmd.com/read/29565728/optic-nerve-sheath-fenestration-a-revised-lateral-approach-for-nerve-access
#19
Nathan W Blessing, David T Tse
Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, describes a disease of poorly understood pathophysiology with a specific set of signs and symptoms including potentially irreversible and blinding visual loss. Optic nerve sheath fenestration (ONSF) is a well-described surgical treatment for patients with IIH and progressive visual loss despite maximally tolerated medical therapy. A number of optic nerve access procedures have been described including medial transconjunctival, superomedial lid crease, and lateral orbitotomy with and without bone takedown...
March 22, 2018: Orbit
https://www.readbyqxmd.com/read/29557388/the-effect-of-increased-intra-abdominal-pressure-on-orbital-subarachnoid-space-width-and-intraocular-pressure
#20
Su-Meng Liu, Ning-Li Wang, Zhen-Tao Zuo, Wei-Wei Chen, Di-Ya Yang, Zhen Li, Yi-Wen Cao
In accordance with the trans-lamina cribrosa pressure difference theory, decreasing the trans-lamina cribrosa pressure difference can relieve glaucomatous optic neuropathy. Increased intracranial pressure can also reduce optic nerve damage in glaucoma patients, and a safe, effective and noninvasive way to achieve this is by increasing the intra-abdominal pressure. The purpose of this study was to observe the changes in orbital subarachnoid space width and intraocular pressure at elevated intra-abdominal pressure...
February 2018: Neural Regeneration Research
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