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Optic nerve sheath

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https://www.readbyqxmd.com/read/29344065/optociliary-shunt-vessels-role-in-diagnosis-and-treatment-of-atypical-pseudotumor-cerebri
#1
Frederico Castelo Moura, Ida Fortini
A 46-year-old man presented with severe visual loss and optic atrophy associated with optociliary shunt vessels. The diagnostic work-up revealed intracranial hypertension and cerebral venous sinus stenosis, with no evidence of previous thrombosis. In view of the severe visual dysfunction, both eyes were submitted to optic nerve sheath fenestration. After surgery, a regression of collateral vessels was observed in both eyes.
August 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/29338967/real-time-optic-nerve-sheath-diameter-measurement-during-lumbar-puncture
#2
Getaw Worku Hassen, Mohammed Al-Juboori, Barbara Koppel, Gokhan Akfirat, Hossein Kalantari
Measurement of optic nerve sheath diameter (ONSD) using point of care ultrasound has been used to indirectly assess the intracranial pressure (ICP) particularly in conditions where it is raised. Direct pressure measurements using probes reaching the ventricle system correlated with ONSD using ultrasound. Attempts were made to measure the ONSD pre and post lumbar puncture (LP) after draining cerebrospinal fluid (CSF) as well as post ventricular shunt placement. We report ONSD measurement and demonstrate dynamic changes during LP in a patient with known idiopathic intracranial hypertension (IIH)...
January 10, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29317136/localization-of-the-zinc-binding-tubulin-polymerization-promoting-protein-in-the-mice-and-human-eye
#3
Robert G Tripon, Judit Oláh, Tajwar Nasir, Lajos Csincsik, Chee Lok Li, Sándor Szunyogh, Haiyan Gong, Jane M Flinn, Judit Ovádi, Imre Lengyel
Tubulin Polymerization Promoting Protein (TPPP/p25) modulates the dynamics and stability of the microtubule network by its bundling and acetylation enhancing activities that can be modulated by the binding of zinc to TPPP/p25. Its expression is essential for the differentiation of oligodendrocytes, the major constituents of the myelin sheath, and has been associated with neuronal inclusions. In this paper, evidence is provided for the expression and localization of TPPP/p25 in the zinc-rich retina and in the oligodendrocytes in the optic nerve...
December 27, 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29313398/a-15-year-review-of-secondary-and-tertiary-optic-nerve-sheath-fenestration-for-idiopathic-intracranial-hypertension
#4
Andrew J Anzeljc, Patrick Frias, Brent R Hayek, Nancy Canter Weiner, Ted H Wojno, H Joon Kim
PURPOSE: Optic nerve sheath fenestration (ONSF) is a common surgical option for patients with idiopathic intracranial hypertension (IIH) with vision loss refractory to medical management. Little is known about the visual benefit of repeated ONSF. The authors aimed to assess the efficacy of secondary and tertiary ONSF in patients with IIH. METHODS: A retrospective chart review was performed on all patients with repeat ONSF for IIH at Emory University from 1999 to 2016...
January 9, 2018: Orbit
https://www.readbyqxmd.com/read/29276604/spontaneous-cerebrospinal-fluid-leak-from-the-optic-canal
#5
Kyle Hannabass, Jeb M Justice
Objective: To present a case of successful repair of a spontaneous cerebrospinal fluid leak in a previously unreported anatomic site. Methods: Retrospective chart review. Results: A 48-year-old woman developed a spontaneous cerebrospinal fluid leak from the optic nerve sheath and underwent a multilayer endoscopic closure with no damage to the optic nerve. Conclusion: Endoscopic surgeons can successfully repair cerebrospinal fluid leaks from the optic nerve sheath without causing loss of vision...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29243006/ocular-ultrasound-for-monitoring-pseudotumor-cerebri-syndrome
#6
Piergiorgio Lochner, Klaus Fassbender, Martin Lesmeister, Raffaele Nardone, Andrea Orioli, Francesco Brigo, Erwin Stolz
The aim of this study was to evaluate the feasibility of ocular ultrasound in the follow-up of pseudotumor cerebri syndrome and to correlate ultrasound with clinical parameters. In a cohort study of 22 consecutive adult patients, ocular ultrasound was performed measuring optic nerve sheath diameter, optic nerve diameter, and optic disc elevation compared with symptoms referred by the patients. The patients showed increased optic nerve sheath diameter [median, 6.51 mm (interquartile range 6.13-7.10)], optic nerve diameter [3...
December 14, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29207432/-sonography-of-the-optic-nerve-a-new-bedside-tool-in-intensive-care
#7
Christopher Hohmann, Konrad R Koch, Roman Pfister, Guido Michels
History and clinical findings Here, we present the case history of a 76-year old man with out-of-hospital cardiac arrest due to a cardiogenic shock and a consecutive no-flow-time of approximately 10 minutes. After 25 minutes of resuscitation procedures a spontaneous return of circulation could be established. The patient was admitted to our center for emergency coronary angiography. After coronary stenting the patient was admitted to our intensive care unit and treated in accordance with the guidelines on cardiogenic shock due to myocardial infarction...
December 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29196990/diagnostic-imaging-ultrasound
#8
Stefan C Kane, Su Lynn Khong, Fabricio da Silva Costa
Diagnostic ultrasound imaging, particularly that which includes pulsed wave Doppler interrogation, is a safe, real-time modality by which the risk of developing preeclampsia can be refined, and the effects of established disease can be assessed. This chapter outlines the rationale and technique for Doppler interrogation of the maternal ophthalmic and uterine arteries and grayscale imaging of the maternal optic nerve sheath diameter.
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29188303/analysis-of-petrous-apex-meningocele-associated-with-meningioma-is-there-any-relation-with-chronic-intracranial-hypertension
#9
Wan-Qun Yang, Jie-Ying Feng, Hong-Jun Liu, Biao Huang, Chang-Hong Liang
PURPOSE: Petrous apex meningocele (PAM) is an uncommon cystic lesion involving the petrous apex. The underlying cause of PAM may be related to chronic elevated intracranial pressure. The aim of the study was to explore the relationship between PAM and meningioma and between PAM and other intracranial hypertension findings. METHODS: Two hundred seventy-eight consecutive patients with meningiomas were retrospectively studied. Fifty age- and gender-matched controls were also enrolled in this study...
February 2018: Neuroradiology
https://www.readbyqxmd.com/read/29171933/transpalpebral-ultrasonographic-measurement-of-the-optic-nerve-sheath-diameter-in-healthy-dogs
#10
Joshua J Smith, Daniel J Fletcher, Stacy D Cooley, Margret S Thompson
OBJECTIVE: To develop a reference range for ultrasonographically measured optic nerve sheath diameter (ONSD-US) in dogs. We hypothesized that ONSD-US can be measured reliably and is associated with weight but not age, sex, or body condition score (BCS), and that the relationship between weight and ONSD-US in dogs is allometric due to canine size variations. DESIGN: Prospective, observational study. SETTING: University teaching hospital. ANIMALS: Seventy-eight healthy adult dogs...
January 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29165748/orbital-arteriovenous-fistula-around-the-optic-nerve-treated-by-transvenous-embolization
#11
Masayuki Sato, Yuji Matsumaru, Tatsuo Amano, Yuki Kamiya
(Background) Intraorbital arteriovenous fistula is a very rare disease, therefore an optimal treatment strategy has not yet been established. Here we describe the use of high-resolution cone-beam CT (CBCT) and selective angiography to visualize the detailed anatomy of orbital vessels. The information provided by the intra-operative imaging led to a change in treatment strategy and eventually to successful transvenous coil embolization. (Clinical presentation) A 55-year-old man presented with right exophthalmos, chemosis and diplopia 4 months previously...
October 11, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29162911/ultrasonographic-measurement-of-the-optic-nerve-sheath-diameter-and-its-association-with-eyeball-transverse-diameter-in-585-healthy-volunteers
#12
Dong Hwan Kim, Jin-Sun Jun, Ryul Kim
The optic nerve sheath diameter (ONSD) is considered as an indirect marker for intracranial pressure (ICP). However, the optimal cut-off value for an abnormal ONSD indicating elevated ICP and its associated factors have been unclear. Thus, we investigated normative values for the ONSD using ultrasonography and investigate the potential factors affecting it. We prospectively recruited healthy volunteers between September 2016 and March 2017. A total of 585 individuals were included, in which the mean ONSD was 4...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29155782/partial-optic-nerve-transection-in-rats-a-model-established-with-a-new-operative-approach-to-assess-secondary-degeneration-of-retinal-ganglion-cells
#13
Fancheng Yan, Sailiang Guo, Yijie Chai, Lan Zhang, Kegao Liu, Qingjun Lu, Ningli Wang, Shuning Li
Previous studies have shown that the secondary degeneration of retinal ganglion cells (RGCs) occurs commonly in glaucoma. Partial optic nerve transection is considered a useful and reproducible model. Compared with other optic nerve injury models used commonly for assessing secondary degeneration, e.g. complete optic nerve transection and optic nerve crush models, the partial optic nerve transection model is superior as it distinguishes primary from secondary degeneration in situ. Therefore, it serves as an excellent tool for evaluating secondary degeneration...
October 15, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29146762/natural-history-of-primary-paediatric-optic-nerve-sheath-meningioma-case-series-and-review
#14
Daniel S Narayan, Ghislaine L Traber, Edwin Figueira, Adnan Pirbhai, Klara Landau, Garry Davis, John Crompton, Dinesh Selva
PURPOSE: To study the natural history, clinical and radiological characteristics of primary paediatric optic nerve sheath meningioma (PPONSM). METHODS: Retrospective study of eight paediatric patients who were treated between 1994 and 2016 at the University Hospital Zurich, Switzerland and the Royal Adelaide Hospital, Australia. Clinical records and imaging studies were reviewed. RESULTS: The mean age at presentation was 11 years (range: 6-17 years)...
November 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29122307/role-of-serial-ultrasonic-optic-nerve-sheath-diameter-monitoring-in-head-injury
#15
A K Thotakura, N R Marabathina, A R Danaboyina, R R Mareddy
OBJECTIVES: To compare optic nerve sheath diameter (ONSD) measurements in head injury patients with a group of normal subjects and investigate the significance of serial ONSD monitoring in head injury patients. METHODS: All patients with a head injury admitted to our hospital with a program of conservative management at the time of admission were included in this prospective study. On admission, the patient was assessed using the Glasgow Coma Scale (GCS), orbital ultrasound for optic nerve sheath diameter (ONSD), and CT brain scan...
December 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29120977/use-of-a-scan-ultrasound-and-optical-coherence-tomography-to-differentiate-papilledema-from-pseudopapilledema
#16
Roberto Saenz, Han Cheng, Thomas C Prager, Laura J Frishman, Rosa A Tang
SIGNIFICANCE: Differentiating papilledema from pseudopapilledema reflecting tilted/crowded optic discs or disc drusen is critical but can be challenging. Our study suggests that spectral-domain optical coherence tomography (OCT) peripapillary retinal nerve fiber layer thickness and retrobulbar optic nerve sheath diameter (ONSD) measured by A-scan ultrasound provide useful information when differentiating the two conditions. PURPOSE: To evaluate the use of A-scan ultrasound and spectral-domain OCT retinal nerve fiber layer thickness (RNFLT) in differentiating papilledema associated with idiopathic intracranial hypertension from pseudopapilledema...
November 9, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29078396/thin-myelin-sheaths-as-the-hallmark-of-remyelination-persist-over-time-and-preserve-axon-function
#17
Ian D Duncan, Rachel L Marik, Aimee T Broman, Moones Heidari
The presence of thin myelin sheaths in the adult CNS is recognized as a marker of remyelination, although the reason there is not a recovery from demyelination to normal myelin sheath thickness remains unknown. Remyelination is the default pathway after myelin loss in all mammalian species, in both naturally occurring and experimental disease. However, there remains uncertainty about whether these thin sheaths thicken with time and whether they remain viable for extended periods. We provide two lines of evidence here that thin myelin sheaths may persist indefinitely in long-lived animal models...
November 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29075198/impacts-of-simulated-weightlessness-by-dry-immersion-on-optic-nerve-sheath-diameter-and-cerebral-autoregulation
#18
Marc Kermorgant, Florian Leca, Nathalie Nasr, Marc-Antoine Custaud, Thomas Geeraerts, Marek Czosnyka, Dina N Arvanitis, Jean-Michel Senard, Anne Pavy-Le Traon
Dry immersion (DI) is used to simulate weightlessness. We investigated in healthy volunteers if DI induces changes in ONSD, as a surrogate marker of intracranial pressure (ICP) and how these changes could affect cerebral autoregulation (CA). Changes in ICP were indirectly measured by changes in optic nerve sheath diameter (ONSD). 12 healthy male volunteers underwent 3 days of DI. ONSD was indirectly assessed by ocular ultrasonography. Cerebral blood flow velocity (CBFV) of the middle cerebral artery was gauged using transcranial Doppler ultrasonography...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29070755/a-case-of-optic-perineuritis-a-literature-review-of-japanese-cases-and-clinical-problems
#19
Makoto Takemaru, Keisuke Tachiyama, Yuji Shiga, Yuhei Kanaya, Yutaka Shimoe, Masaru Kuriyama
A 64-year-old woman was admitted to our hospital owing to decreased visual acuity and visual field defect. She had a similar history of decreased visual acuity and received steroid therapy 10 years ago. Brain MRI revealed gadolinium-enhancement in the sheath of the optic nerve, called "tram-track" and "doughnut" signs. Optic perineuritis (OPN) was diagnosed on the basis of her clinical manifestations, which improved on treatment with high-dose methylprednisolone (mPSL). However, clinical manifestations relapsed 10 days post-discharge; hence, she was re-admitted...
October 26, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29044088/management-of-idiopathic-intracranial-hypertension-in-an-infant-with-bilateral-congenital-cataract-and-associated-comitant-sensory-esotropia
#20
Jyoti Himanshu Matalia, Sheetal Shirke, Hemant Anaspure, Pooja Ghalla, Minal Kekatpure
In this report, we describe the management of a child with bilateral cataract, nystagmus, and comitant sensory esotropia. Routine ultrasonography done before cataract surgery revealed bilateral disc edema confirmed as idiopathic intracranial hypertension by a pediatric neurologist. The primary intervention for cataract surgery was followed by nonresolving papilledema, despite maximum medical therapy. To salvage the optic nerve function in a nonverbal child, bilateral optic nerve sheath decompression was planned with simultaneous medial rectus recessions for the persistent esotropia with the satisfactory postoperative outcome...
October 2017: Indian Journal of Ophthalmology
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