Matti Uusitupa, Tauseef A Khan, Effie Viguiliouk, Hana Kahleova, Angela A Rivellese, Kjeld Hermansen, Andreas Pfeiffer, Anastasia Thanopoulou, Jordi Salas-Salvadó, Ursula Schwab, John L Sievenpiper
Prevention of type 2 diabetes (T2D) is a great challenge worldwide. The aim of this evidence synthesis was to summarize the available evidence in order to update the European Association for the Study of Diabetes (EASD) clinical practice guidelines for nutrition therapy. We conducted a systematic review and, where appropriate, meta-analyses of randomized controlled trials (RCTs) carried out in people with impaired glucose tolerance (IGT) (six studies) or dysmetabolism (one study) to answer the following questions: What is the evidence that T2D is preventable by lifestyle changes? What is the optimal diet (with a particular focus on diet quality) for prevention, and does the prevention of T2D result in a lower risk of late complications of T2D? The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was applied to assess the certainty of the trial evidence...
November 1, 2019: Nutrients