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https://www.readbyqxmd.com/read/29344319/sandalwood-album-oil-as-a-botanical-therapeutic-in-dermatology
#1
REVIEW
Ronald L Moy, Corey Levenson
Many skin conditions and diseases are characterized by inflammation, infection, and hyperplasia. Safe and effective topical treatment options that can be used long-term are needed. Traditional botanical medicines, which are often complex mixtures that exert their biological activities via multiple mechanisms of action, are being studied as potential new active ingredients in dermatology. Sandalwood album oil (SAO), also known as East Indian sandalwood oil (EISO), is an essential oil distilled from the Santalum album tree and has demonstrated biological activity as an anti-inflammatory, anti-microbial, and anti-proliferative agent...
October 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29329128/expanding-the-morphologic-heterogeneity-of-stromal-changes-in-molluscum-contagiosum-infection
#2
Kristen N Ruby, Ann E Perry, Konstantinos Linos
No abstract text is available yet for this article.
January 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29319288/an-unusual-reaction-to-molluscum-contagiosum
#3
Iria Neri, Camilla Loi, Michela Magnano, Paola Sgubbi, Annalisa Patrizi
No abstract text is available yet for this article.
February 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29282454/interventions-for-nongenital-molluscum-contagiosum-in-persons-without-immune-deficiency
#4
Johannes C van der Wouden, Sander Koning, Kenneth A Katz
Clinical Question: How effective and safe are treatments for nongenital molluscum contagiosum in persons without immune deficiency? Bottom Line: Compared with placebo, imiquimod, 5%, cream was not more effective in clearing molluscum contagiosum and caused more local adverse effects, including application site reactions, in children aged 2 to 12 years; because high-quality evidence for other interventions is lacking, allowing for natural resolution of the infection remains a reasonable approach...
December 27, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29274346/a-new-method-for-removal-of-eyelid-margin-molluscum
#5
Sanjay Khare, Saurabh Dubey, Rahul Nagar
No abstract text is available yet for this article.
December 20, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29241785/cantharidin-for-treatment-of-facial-molluscum-contagiosum-a-retrospective-review
#6
Marla N Jahnke, Sook Hwang, James L Griffith, Tor Shwayder
No abstract text is available yet for this article.
January 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29204384/approach-to-a-child-with-primary-immunodeficiency-made-simple
#7
REVIEW
Dhrubajyoti Sharma, Ankur K Jindal, Amit Rawat, Surjit Singh
Primary immunodeficiency disorders (PIDs) are a group of disorders affecting the capability to fight against infection. These include defects in T cells and B cells affecting cell-mediated and humoral immunity, respectively, combined humoral and cell-mediated immunodeficiency, defects in phagocytosis, complement defects, and defects in cytokine or cytokine signalling pathways which are detrimental for immune function. Depending upon the type and severity, age at onset of symptoms can vary from neonatal period to late childhood...
November 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29166239/molluscum-contagiosum-in-a-patient-with-atopic-dermatitis
#8
Katerina Damevska, Arben Emurlai
A 7-year-old boy presented to the dermatology clinic with a 3-month history of widespread, mildly pruritic skin lesions. He had a history of atopic dermatitis that had been treated with topical glucocorticoids for several months. The skin examination revealed numerous flesh-colored papules..
November 23, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29165834/juvenile-xanthogranuloma-with-angiomatous-appearance-and-a-peculiar-immunophenotype
#9
Joaquín López-Robles, Lucía Núñez, Elena Macias-Del-Toro, José Luis Ramírez-Bellver, José Luis Díaz, Luis Requena
Juvenile xanthogranuloma is the most common form of non-Langerhans cell histiocytosis in childhood. The clinical differential diagnosis of a solitary juvenile xanthogranuloma includes molluscum contagiosum, Spitz nevus, and melanoma. Lesions larger than 2 cm in diameter may be misdiagnosed as hemangiomas, but this is not typical of smaller juvenile xanthogranuloma. We report a case of solitary juvenile xanthogranuloma in a 10-year-old boy with angiomatous appearance and peculiar immunophenotype.
November 22, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29162529/vulvar-nodules-a-rare-presentation-of-mastocytosis
#10
Ashli Lawson, Adnan Mir, Ellen E Wilson
BACKGROUND: Mastocytosis is a rare benign disorder characterized by the finding of mast cells in the skin and other organs, occurring in both adult and pediatric age groups. The cutaneous form is the most common presentation in childhood and is rarely located on the vulva. CASE: A 9 year old prepubertal girl presented with bilateral vulvar nodules found incidentally by her pediatrician. Biopsy and histopathologic review confirmed mastocytosis. Her lesions significantly diminished over the following year...
November 18, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/29145905/-a-girl-with-a-tumour-on-the-thorax
#11
M B Notenboom-Kool, W Opstelten
A healthy 1-year old girl visits her general practitioner with a solitary dome-shaped tumour on her thorax. The lesion is about one cm in diameter and is present since several months. Pathological research reveals a solitary giant molluscum contagiosum. This is a common viral disease of the childhood. In contrast to this case, mollusca contagiosa typically present as several small papules.
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29120484/elisa-for-molluscum-contagiosum-virus
#12
Subuhi Sherwani, Mohammed Chowdhury, Joachim J Bugert
Molluscum contagiosum virus (MCV) is a common skin pathogen of children and young adults. Infection with MCV causes benign skin tumors in children and young adults and is mostly self-limiting. In contrast to orthopoxviruses, MCV infections tend to take a subacute clinical course but may persist for up to 12 months. Current numbers for MCV seroprevalence in different geographical areas are based on a variety of historical serological methods from complement fixation assays to MCV ELISAs based on purified MCV virions and MC133 antigen expressed in a Semliki Forest Virus expression system...
November 9, 2017: Current Protocols in Microbiology
https://www.readbyqxmd.com/read/29103323/treatment-of-molluscum-contagiosum-with-an-east-indian-sandalwood-oil-product
#13
Malika Haque, Daniel L Coury
OBJECTIVES: To evaluate the safety and efficacy of an East Indian sandalwood oil (EISO) product as a topical treatment for molluscum contagiosum. MATERIALS AND METHODS: Ten subjects ranging in age from 22 months to 29 years were recruited. Subjects were instructed to apply an EISO product to the lesions twice daily. Subjects were monitored every two to three weeks during the study and were questioned regarding local or systemic side effects. Assessment of response was recorded by counting lesions and documented by photographs...
November 22, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29027896/molluscum-contagiosum-and-pubic-hair-removal-in-male-patients
#14
Gino Antonio Vena, Nicoletta Cassano
No abstract text is available yet for this article.
November 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29024216/acrochordons-on-the-neck-a-remarkable-clinical-feature-of-tuberous-sclerosis-showing-different-patterns
#15
C Baykal
Sachs and Lipsker(1) recently published a few patients diagnosed with tuberous sclerosis (TS) presenting with multiple loosely arranged acrochordons (molluscum pendulum) located on the posterior neck showing a lace-like distribution and they proposed the term "molluscum pendulum necklace sign" for these typically located lesions. They detected acrochordons in five cases (17%) in a retrospectively analysed consecutive series of 29 TS patients, of whom four (three adults and one child) remarkably showed this typical pattern...
October 12, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29023949/more-about-molluscum-pendulum-acrochordons-in-tuberous-sclerosis-complex
#16
Dan Lipsker
I thank Dr Baykal for his interest in our recent work about the clinical relevance of molluscum pendulum/acrochordons in patients with tuberous sclerosis complex (TSC) (1).He confirms and expands our own findings (2). He correctly insists that MP are not only located on the (posterior) neck, as was also the case in 2 of the 4 patients with TSC and MP that we reported. More widespread involvement, especially of the lateral and anterior aspect of the neck and the upper back, were frequent in the patients he reports...
October 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28885709/prenylation-of-viral-proteins-by-enzymes-of-the-host-virus-driven-rationale-for-therapy-with-statins-and-ft-ggt1-inhibitors
#17
REVIEW
Ekaterina S Marakasova, Birgit Eisenhaber, Sebastian Maurer-Stroh, Frank Eisenhaber, Ancha Baranova
Intracellular bacteria were recently shown to employ eukaryotic prenylation system for modifying activity and ensuring proper intracellular localization of their own proteins. Following the same logic, the proteins of viruses may also serve as prenylation substrates. Using extensively validated high-confidence prenylation predictions by PrePS with a cut-off for experimentally confirmed farnesylation of hepatitis delta virus antigen, we compiled in silico evidence for several new prenylation candidates, including IRL9 (CMV) and few other proteins encoded by Herpesviridae, Nef (HIV-1), E1A (human adenovirus 1), NS5A (HCV), PB2 (influenza), HN (human parainfluenza virus 3), L83L (African swine fever), MC155R (molluscum contagiosum virus), other Poxviridae proteins, and some bacteriophages of human associated bacteria...
September 8, 2017: BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
https://www.readbyqxmd.com/read/28884917/molluscum-contagiosum-review-and-update-on-management
#18
REVIEW
Emily Forbat, Firas Al-Niaimi, Faisal R Ali
Molluscum contagiosum (MC) is an infectious dermatosis that commonly presents in children and immunocompromised individuals. Although lesions usually resolve spontaneously after several months, they can be symptomatic and cause psychosocial distress. We review the evidence underlying treatment methods available for MC lesions, including potassium hydroxide, salicylic acid, hydrogen peroxide, retinoids, cantharidin, cryotherapy, curettage, and pulsed dye laser to aid practicing dermatologists in therapy selection...
September 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28871935/topical-imiquimod-is-an-effective-and-safe-drug-for-molluscum-contagiosum-in-children
#19
George Badavanis, Efstathia Pasmatzi, Alexandra Monastirli, Sophia Georgiou, Dionysios Tsambaos
Dear Editor, Molluscum contagiosum (MC) is a very common skin infection caused by a molluscipox virus gene of the poxvirus family. It usually occurs in young children, sexually active adults, and immunocompromised individuals. The typical clinical picture of this infection is characterized by asymptomatic flesh-colored, single or multiple papules, measuring 2-6 mm in diameter with a central umbilication that occur on the skin and the mucous membranes. In adults, the skin lesions are predominantly located in the genital region, whereas in children they are found on the trunk, the extremities, and the face...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28866311/filaggrin-mutations-and-molluscum-contagiosum-skin-infection-in-patients-with-atopic-dermatitis
#20
Sara Manti, Maria Amorini, Caterina Cuppari, Annamaria Salpietro, Francesca Porcino, Salvatore Leonardi, Michele Miraglia Del Giudice, Gianluigi Marseglia, Davide Paolo Caimmi, Carmelo Salpietro
BACKGROUND: Although mutations in the filaggrin (FLG) gene have been reported to predispose patients with atopic dermatitis (AD) skin infection susceptibility, to date, the data reported in the literature are still controversial. OBJECTIVE: To evaluate the role of FLG polymorphisms expression and risk of developing a concomitant Molluscum contagiosum sustained skin infection in the pediatric population with AD. METHODS: A total of 100 children with AD and 97 healthy children were enrolled...
August 30, 2017: Annals of Allergy, Asthma & Immunology
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