Karthik Nagaraja Rao, Ripudaman Arora, Prajwal Dange, Nitin Nagarkar, Antti A Mäkitie, Luiz P Kowalski, Avraham Eisbruch, Marc Hamoir, Francisco J Civantos, Vincent Vander Poorten, Sweet Ping Ng, Sandra Nuyts, Mark Zafereo, Ameya A Asarkar, Paweł Golusinski, Ohad Ronen, Alfio Ferlito
OBJECTIVE: To determine the overall surgical outcomes of infranotch T4b oral cancers and compare them with T4a oral cancers. METHODS: PubMed, EMBASE and Cochrane databases from 2000 to 2022 were systematically searched. Clinical studies reporting at least one outcome following curative surgery and adjuvant therapy for comparison of patients with either infranotch T4b (IN-T4b) or T4a tumour. The heterogeneity of the included studies was determined using Tau-squared, Chi-squared, and the Higgins I2 test...
October 7, 2023: Oncology and Therapy