keyword
MENU ▼
Read by QxMD icon Read
search

Breast cancer in young women

keyword
https://www.readbyqxmd.com/read/28925272/-fertility-preserving-methods-in-women-with-breast-cancer-before-gonadotoxic-therapy
#1
N Halászová, I Crha, M Huser, V Weinberger, J Žáková, M Ješeta, E Lousová, E Filipinská, P Ventruba
OBJECTIVE: To present current options and own experiences with ovarian stimulation in young women with breast cancer before gonadotoxic therapy. DESIGN: Review article with own experiencies. METHODS: Literary search, analysis of own experiences with complex therapy in women with breast cancer planning pregnancy, definitions of stimulating protocols, using methods of assisted reproduction. SETTING: Department of Obstetrics and Gynecology, Faculty of Medicine, Masaryk University and University Hospital Brno...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28912475/the-impact-of-young-age-for-prognosis-by-subtype-in-women-with-early-breast-cancer
#2
Weibin Lian, Fangmeng Fu, Yuxiang Lin, Minjun Lu, Boyang Chen, Peidong Yang, Bangwei Zeng, Meng Huang, Chuan Wang
Young age (≤40 years) use to be considered an independent risk factor for the prognosis of women with early-stage breast cancer. We conducted a retrospective analysis to investigate this claim in a population of young patients who were stratified by molecular subtype. We identified 2,125 women with stage I to III breast cancer from the Fujian Medical University Union Hospital. Multivariable Cox proportional hazards models were used to analyze the relationship between age groups stratified by molecular subtype and 5-year disease-free survival (DFS), 5-year distant metastasis-free survival (DMFS), and 5-year breast cancer-specific survival (BCSS)...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28903991/biology-and-etiology-of-young-onset-breast-cancers-among-premenopausal-african-american-women-results-from-the-amber-consortium
#3
Lynn Chollet-Hinton, Andrew F Olshan, Hazel B Nichols, Carey K Anders, Jennifer L Lund, Emma H Allott, Traci N Bethea, Chi-Chen Hong, Stephanie M Cohen, Thaer Khoury, Gary R Zirpoli, Virginia F Borges, Lynn A Rosenberg, Elisa V Bandera, Christine B Ambrosone, Julie R Palmer, Melissa A Troester
BACKGROUND: African American (AA) women have higher incidence of aggressive, young-onset (<40 years) breast cancers. Young- and older-onset disease may have distinct tumor biologies and etiologies; however, studies investigating age differences among AA women have been rare and generally underpowered. METHODS: We examined tumor characteristics and breast cancer risk factors associated with premenopausal young (<40) vs. older (≥40) AA women's breast cancer in the African American Breast Cancer Epidemiology and Risk Consortium (2,008 cases and 5,144 controls)...
September 13, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28900476/breast-cancer-in-angola-molecular-subtypes-a-first-glance
#4
Fernando Miguel, Lygia Vieira Lopes, Eduardo Ferreira, Emília Ribas, Alexis Fuentes Pelaez, Conceição Leal, Teresina Amaro, Paula Lopes, Cristina Mendes Santos, Carlos Lopes, Lúcio Lara Santos
PURPOSE: The aim of this study was to investigate the breast cancer (BC) molecular subtypes according to its surrogate immunohistochemistry (IHC) markers. We conducted a preliminary study, to correlate the clinical pathological profiles and molecular subtypes of breast cancer in Luanda, Angola. METHODS: From January 2011 to 30 December 2014, 140 consecutive cases of microscopically confirmed invasive breast carcinoma were classified regarding histology and IHC (ER, PR, HER2, and Ki-67)...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28894168/the-association-of-young-age-with-local-recurrence-in-women-with-early-stage-breast-cancer-after-breast-conserving-therapy-a-meta-analysis
#5
Xiang-Ming He, De-Hong Zou
The aim of this meta-analysis is to determine the relationship between young age and local recurrence in patients with early-stage breast cancer after breast-conserving therapy. Eligible studies were retrieved from various electronic databases. Among the 19 studies included, 14 studies were analyzed for 5-year local recurrence rate and 8 studies for 10-year local recurrence rate using random effects models. Both results showed that young patients were at higher risk of local recurrence compared to old patients (5-year: RR = 2...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28888722/breast-cancer-risk-after-radiation-therapy-for-hodgkin-lymphoma-influence-of-gonadal-hormone-exposure
#6
Inge M Krul, Annemieke W J Opstal-van Winden, Berthe M P Aleman, Cécile P M Janus, Anna M van Eggermond, Marie L De Bruin, Michael Hauptmann, Augustinus D G Krol, Michael Schaapveld, Annegien Broeks, Karen R Kooijman, Sandra Fase, Marnix L Lybeert, Josée M Zijlstra, Richard W M van der Maazen, Ausrele Kesminiene, Ibrahima Diallo, Florent de Vathaire, Nicola S Russell, Flora E van Leeuwen
BACKGROUND: Young women treated with chest radiation therapy (RT) for Hodgkin lymphoma (HL) experience a strongly increased risk of breast cancer (BC). It is unknown whether endogenous and exogenous gonadal hormones affect RT-associated BC risk. METHODS: We conducted a nested case-control study among female 5-year HL survivors treated before age 41. Hormone exposure and HL treatment data were collected through medical records and questionnaires for 174 BC case patients and 466 control patients...
July 18, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28887687/kaiso-is-highly-expressed-in-tnbc-tissues-of-women-of-african-ancestry-compared-to-caucasian-women
#7
Blessing I Bassey-Archibong, Shawn M Hercules, Lyndsay G A Rayner, Desiree H A Skeete, Suzanne P Smith Connell, Ian Brain, Adetola Daramola, Adekunbiola A F Banjo, Jung S Byun, Kevin Gardner, Jonathan Dushoff, Juliet M Daniel
PURPOSE: Triple-negative breast cancer (TNBC) is most prevalent in young women of African ancestry (WAA) compared to women of other ethnicities. Recent studies found a correlation between high expression of the transcription factor Kaiso, TNBC aggressiveness, and ethnicity. However, little is known about Kaiso expression and localization patterns in TNBC tissues of WAA. Herein, we analyze Kaiso expression patterns in TNBC tissues of African (Nigerian), Caribbean (Barbados), African American (AA), and Caucasian American (CA) women...
September 8, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28884745/clinicopathologic-and-genetic-characteristics-of-young-patients-with-pleural-diffuse-malignant-mesothelioma
#8
Marina Vivero, Raphael Bueno, Lucian R Chirieac
Pleural diffuse malignant mesothelioma typically presents during the seventh decade of life and has poor prognosis. Recent epidemiologic studies have shown differences between young and older mesothelioma patients, but the biology of pleural mesothelioma in young patients is poorly understood. We studied the clinicopathologic and genetic characteristics in pleural mesothelioma patients aged 35 years and younger. Thirty-six consecutive pleural mesothelioma patients aged 35 years and younger were compared with 48 older patients...
September 8, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28877720/reduced-ovarian-reserve-in-young-early-breast-cancer-patients-preliminary-data-from-a-prospective-cohort-trial
#9
Antonia Wenners, Jana Grambach, Juliane Koss, Nicolai Maass, Walter Jonat, Andreas Schmutzler, Christoph Mundhenke
BACKGROUND: The numerous side effects of chemotherapy in patients with breast cancer are well known. However, the precise effects of chemotherapy on ovarian function in premenopausal women are poorly investigated. The patients are at risk of developing sexual hormone deficiency and impaired fertility. This prospective cohort study addresses predictive parameters of ovarian reserve after chemotherapy. METHODS: Fifty-one premenopausal women (28-46 years) with primary breast cancer were included in the trial...
September 6, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28856726/increased-risk-of-breast-cancer-at-a-young-age-in-women-with-fibrous-dysplasia
#10
Bas C J Majoor, Alison M Boyce, Judith V M G Bovée, Vincent T H B M Smit, Michael T Collins, Anne-Marie Cleton-Jansen, Olaf M Dekkers, Neveen A T Hamdy, Sander P D Dijkstra, Natasha M Appelman-Dijkstra
Background Fibrous dysplasia is a rare bone disorder caused by mutations of the GNAS-gene, which are also identified in malignancies. We explored the potential relationship between breast cancer and fibrous dysplasia in two fibrous dysplasia cohorts from the Netherlands and the USA Patients and Methods Data on fibrous dysplasia and breast cancer diagnosis were retrieved from hospital-records of 134 (Netherlands) and 121 (USA) female patients. Results were validated with breast cancer data of 645 female fibrous dysplasia patients from the Dutch Pathology Registry (PALGA)...
August 30, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28845050/preservation-of-fertility-or-ovarian-function-in-patients-with-breast-cancer-or-gynecologic-and-internal-malignancies
#11
Angrit Stachs, Steffi Hartmann, Bernd Gerber
Because of the efficacy of systemic therapies, neoplasias which occur in pediatric and adolescent patients and in young adults have high cure rates. This means that fulfilling their wish to have children has become a more pressing concern, particularly among young women with malignant tumors. Premature ovarian failure is also a not insignificant problem as it has a lasting detrimental effect on quality of life. Every oncology patient who may potentially wish to have children should be informed about their options for preserving fertility prior to starting treatment...
August 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28844016/breast-cancer-in-young-women-and-prognosis-how-important-are-proliferation-markers
#12
Hanna Fredholm, Kristina Magnusson, Linda S Lindström, Nicholas P Tobin, Henrik Lindman, Jonas Bergh, Lars Holmberg, Fredrik Pontén, Jan Frisell, Irma Fredriksson
AIM: Compared to middle-aged women, young women with breast cancer have a higher risk of systemic disease. We studied expression of proliferation markers in relation to age and subtype and their association with long-term prognosis. METHODS: Distant disease-free survival (DDFS) was studied in 504 women aged <40 years and 383 women aged ≥40 years from a population-based cohort. Information on patient characteristics, treatment and follow-up was collected from medical records...
August 24, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28838807/skeletal-health-in-breast-cancer-survivors
#13
REVIEW
Olivier Bruyère, Pierre Bergmann, Etienne Cavalier, Evelien Gielen, Stefan Goemaere, Jean-Marc Kaufman, Serge Rozenberg, Jean-Jacques Body
Although some risk factors for breast cancer might be protective for osteoporosis, several cross-sectional studies have reported, nevertheless, that patients with breast cancer have a lower bone mass and potentially a higher incidence of fractures than expected. In any case, it appears that patients with breast cancer are not protected from osteoporosis, which provides further support for the recommendation that bone health is assessed after a diagnosis of breast cancer. Most adjuvant therapies will lead to increased bone loss and a higher fracture rate...
August 18, 2017: Maturitas
https://www.readbyqxmd.com/read/28831642/different-prognosis-of-young-breast-cancer-patients-in-their-20s-and-30s-depending-on-subtype-a-nationwide-study-from-the-korean-breast-cancer-society
#14
Jai Min Ryu, Jonghan Yu, Seung Il Kim, Ku Sang Kim, Hyeong-Gon Moon, Jung Eun Choi, Joon Jeong, Kyung Do Byun, Seok Jin Nam, Jeong Eon Lee, Se Kyung Lee, Seok Won Kim
PURPOSE: Numerous studies have demonstrated that breast cancer in young women (BCY) has unfavorable prognostic features and more unfavorable subtypes. However, few studies have evaluated the effect of subtype disparities on breast cancer prognosis by age, especially for BCY. We analyzed breast cancer mortality stratified by tumor subtype according to age among patients younger than 50 years. METHODS: Data from the Korean Breast Cancer Society Registry for patients diagnosed with invasive breast cancer when aged less than 50 years between 2003 and 2010 were reviewed retrospectively...
August 22, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28831437/paloma-3-phase-iii-trial-of-fulvestrant-with-or-without-palbociclib-in-premenopausal-and-postmenopausal-women-with-hormone-receptor-positive-human-epidermal-growth-factor-receptor-2-negative-metastatic-breast-cancer-that-progressed-on-prior-endocrine-therapy
#15
Hiroji Iwata, Seock-Ah Im, Norikazu Masuda, Young-Hyuck Im, Kenichi Inoue, Yoshiaki Rai, Rikiya Nakamura, Jee Hyun Kim, Justin T Hoffman, Ke Zhang, Carla Giorgetti, Shrividya Iyer, Patrick T Schnell, Cynthia Huang Bartlett, Jungsil Ro
PURPOSE: To assess efficacy and safety of palbociclib plus fulvestrant in Asians with endocrine therapy-resistant metastatic breast cancer. PATIENTS AND METHODS: The Palbociclib Ongoing Trials in the Management of Breast Cancer 3 (PALOMA-3) trial, a double-blind phase III study, included 521 patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer with disease progression on endocrine therapy. Patient-reported outcomes (PROs) were assessed on study treatment and at the end of treatment...
August 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28830795/indications-for-postmastectomy-radiation-after-neoadjuvant-chemotherapy-in-ypn0-and-ypn1-3-axillary-node-positive-women
#16
Barbara Fowble, Abhishek Keshav Jairam, Frederick Wang, Anne Peled, Michael Alvarado, Cheryl Ewing, Laura Esserman, Catherine Park, Ann Lazar
INTRODUCTION: Downstaging with neoadjuvant chemotherapy (NAC) might obscure indications for postmastectomy radiation (PMRT). The degree of downstaging that results in local-regional recurrence (LRR) rates low enough to omit PMRT remains controversial. We examined the rate of LRR in women who received NAC who underwent mastectomy without PMRT. PATIENTS AND METHODS: Between 2004 and 2013, 81 women with stage I to IIIA breast cancer had NAC and mastectomy; 48 patients (59%) were clinical N0 and 33 patients (41%) were clinical N1; median age was 45 years; 33 patients (41%) had hormone receptor-positive (HR(+))HER2(-), 21 patients (26%) HR(+)HER2(+), 19 patients (23%) HR(-) HER2(-), and 7 patients (9%) HR(-)HER2(+) disease...
August 1, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28822332/eso-esmo-3rd-international-consensus-guidelines-for-breast-cancer-in-young-women-bcy3
#17
Shani Paluch-Shimon, Olivia Pagani, Ann H Partridge, Omalkhair Abulkhair, Maria-João Cardoso, Rebecca Alexandra Dent, Karen Gelmon, Oreste Gentilini, Nadia Harbeck, Anita Margulies, Dror Meirow, Giancarlo Pruneri, Elzbieta Senkus, Tanja Spanic, Medha Sutliff, Luzia Travado, Fedro Peccatori, Fatima Cardoso
The 3rd International Consensus Conference for Breast Cancer in Young Women (BCY3) took place in November 2016, in Lugano, Switzerland organized by the European School of Oncology (ESO) and the European Society of Medical Oncologists (ESMO). Consensus recommendations for the management of breast cancer in young women were updated from BCY2 with incorporation of new evidence to inform the guidelines, and areas of research priorities were identified. This manuscript summarizes the ESO-ESMO international consensus recommendations, which are also endorsed by the European Society of Breast Specialists (EUSOMA)...
October 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28822001/trends-in-stage-specific-breast-cancer-incidence-in-new-south-wales-australia-insights-into-the-effects-of-25%C3%A2-years-of-screening-mammography
#18
Gemma Jacklyn, Kevin McGeechan, Les Irwig, Nehmat Houssami, Stephen Morrell, Katy Bell, Alexandra Barratt
PURPOSE: Screening mammography aims to improve breast cancer (BC) prognosis by increasing the incidence of early-stage tumours in order to decrease the incidence of late-stage cancer, but no reports have investigated these potential effects in an Australian population. Therefore we aimed to identify temporal trends in stage-specific BC in New South Wales (NSW), Australia, between 1972 and 2012. METHODS: An observational study of women who received a diagnosis of BC from 1972-2012 as recorded in the NSW Cancer Registry, a population-based registry with almost complete coverage and high rates of histological verification...
August 19, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28820618/college-women-s-responses-to-a-celebrity-health-disclosure
#19
Julia H Drizin, Vanessa L Malcarne, Melody K Schiaffino, Kristen J Wells
Celebrities can have a powerful influence on people's health-related attitudes and behaviors, often by publicly disclosing their own personal health decisions. In May 2013, Angelina Jolie, an internationally recognized actress, director, and author, wrote an op-ed for the New York Times disclosing her decision to undergo a prophylactic double mastectomy to reduce her risk of breast cancer after learning that she carried the BRCA1 gene mutation. This cross-sectional study examined whether exposure to Angelina Jolie and her mastectomy disclosure and parasocial involvement (PSI) with Angelina Jolie were related to female college students' perceived risk of breast cancer and breast cancer screening intentions...
August 18, 2017: Health Communication
https://www.readbyqxmd.com/read/28819909/adjunctive-breast-specific-gamma-imaging-for-detecting-cancer-in-women-with-calcifications-at-mammography
#20
Hyun Woo Chung, Young So, Jung-Hyun Yang, Kyoung Sik Park, Young Bum Yoo, Nami Choi, Mi Young Kim, Jayoun Kim, Eun Jeong Lee
BACKGROUND: Mammography detects calcium deposits sensitively, but the specificity for differentiating malignancy from benign calcifications is low. Thus, we investigated whether adjunctive breast-specific gamma imaging (BSGI) has incremental value for detecting cancer in women with suspicious calcifications detected by mammography, and compared BSGI with adjunctive ultrasonography (US). METHODS: The medical records of women without a personal history of breast cancer who underwent mammography for breast evaluation from 2009 to 2014 were reviewed retrospectively...
August 17, 2017: Annals of Surgical Oncology
keyword
keyword
84812
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"