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https://www.readbyqxmd.com/read/28649655/gene-expression-in-breast-and-adipose-tissue-after-12-months-of-weight-loss-and-vitamin-d-supplementation-in-postmenopausal-women
#1
Caitlin Mason, Lei Wang, Catherine Duggan, Ikuyo Imayama, Sushma S Thomas, Ching-Yun Wang, Larissa A Korde, Anne McTiernan
Adipose tissue is involved in the etiology of postmenopausal breast cancer, possibly through increased sex steroid hormone production, inflammation, and altered adipokines. Vitamin D may affect these pathways but its effect on gene expression in different tissues has not been examined. Within a double-blind, 12-month placebo-controlled randomized trial, we compared 2000 IU/day oral vitamin D3 supplementation (N = 39) vs. placebo (N = 40) on the expression of 5 genes in breast and adipose tissue in overweight/obese postmenopausal women (50-75 years)...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28647969/-knowledge-attitude-and-practice-to-chronic-diseases-and-associated-influencing-factors-in-uygur-population-in-kashgar-area-of-xinjiang-uygur-autonomous-region
#2
Z B Zhang, Z X Xue, M M Ma, Y H Li, D M Luo, X L Song, X F Chao, G Wang, Nurmamat Nazibam, Bawudun Ayxamgul, Mahat Sulayman, X J Wu, Z Y Zhou, B S Sun, Y Z Wang, M Wang
Objective: To investigate the knowledge, attitude and practice (KAP) to chronic diseases and associated influencing factors in Uygur adults in Kashgar of southern Xinjiang, and provide basic information for developing ethnic specific prevention and control strategies for chronic diseases. Methods: With stratified cluster random sampling, investigations, including questionnaire survey, physical examination and laboratory tests were performed among local residents who were aged ≥18 years and selected in Shufu county in southern Xinjiang...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28634547/kinesiophobia-pain-muscle-functions-and-functional-performances-among-older-persons-with-low-back-pain
#3
Nor Azizah Ishak, Zarina Zahari, Maria Justine
OBJECTIVES: This study aims (1) to determine the association between kinesiophobia and pain, muscle functions, and functional performances and (2) to determine whether kinesiophobia predicts pain, muscle functions, and functional performance among older persons with low back pain (LBP). METHODS: This is a correlational study, involving 63 institutionalized older persons (age = 70.98 ± 7.90 years) diagnosed with LBP. Anthropometric characteristics (BMI) and functional performances (lower limb function, balance and mobility, and hand grip strength) were measured...
2017: Pain Research and Treatment
https://www.readbyqxmd.com/read/28627195/exercise-improved-semen-quality-and-reproductive-hormone-levels-in-sedentary-obese-adults
#4
Miguel Ángel Rosety, Antonio Jesus Díaz, Jesús María Rosety, María Teresa Pery, Francisco Brenes-Martín, Marco Bernardi, Natalia García, Manuel Rosety-Rodríguez, Francisco Javier Ordoñez, Ignacio Rosety
INTRODUCTION: From the previously published literature on the relationship between obesity and infertility, it is clear that male obesity negatively impacts semen quality. Accordingly, this study was conducted to determine whether regular exercise may improve semen quality in sedentary obese adults. MATERIAL AND METHODS: Ninety obese adults were randomly allocated to the intervention (n = 45) or control group (n = 45). Participants in the intervention group performed a 16-week aerobic training program in a treadmill, three sessions per week, consisting of a warm-up (10-15 minutes), 35-50 minutes treadmill exercise (increasing five minutes per four weeks) at a work intensity of 50-65% of peak heart rate (increasing a 5% per four weeks) and cooling-down (5-10 minutes)...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28626911/clinical-findings-and-management-of-153-horses-with-large-colon-sand-accumulations
#5
Isabelle Kilcoyne, Julie E Dechant, Sharon J Spier, Mathieu Spriet, Jorge E Nieto
OBJECTIVE: To determine the influence of radiographic quantification of sand accumulation on the medical versus surgical management of large colon sand accumulations. To compare short- and long-term outcomes and complications associated with medical and surgical management of these horses. STUDY DESIGN: Retrospective. SAMPLE POPULATION: A total of 153 horses. METHODS: Medical records and abdominal radiographs of horses presented for colic between 2004 and 2014 were reviewed...
June 19, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28625710/effect-of-an-individualised-physical-exercise-program-on-lipid-profile-in-sedentary-patients-with-cardiovascular-risk-factors
#6
Francisco Javier Rubio Pérez, Luis Franco Bonafonte, Daiana Ibarretxe Guerediaga, Maria Pilar Oyon Belaza, Paola Ugarte Peyron
Physical exercise has become in an important tool in the reduction of cardiovascular risk. OBJECTIVES: To evaluate the effectiveness of an unsupervised physical exercise program that on the physical condition and the lipid profile. METHOD: The final sample included 49 sedentary men and women, who were non-smokers, with dyslipidaemia, overweight, and type1 obesity. The 4-month program included walking for 30-60minutes every day, and for three days a week, 30minutes of cycling at an intensity of 40-60% of maximum functional capacity, as well as isometric abdominals and static stretching...
June 15, 2017: Clínica e Investigación en Arteriosclerosis
https://www.readbyqxmd.com/read/28619403/practice-knowledge-and-barriers-for-screening-of-hepatocellular-carcinoma-among-high-risk-chinese-patients
#7
Kerui Xu, Shinobu Watanabe-Galloway, Fedja A Rochling, Jianjun Zhang, Paraskevi A Farazi, Hongyan Peng, Hongmei Wang, Jiangtao Luo
BACKGROUND: Hepatocellular carcinoma (HCC) is among the leading causes of cancer deaths in China. Considering its poor prognosis when diagnosed late, Chinese guidelines recommend biannual screening for HCC with abdominal ultrasound and serum α-fetoprotein (AFP) test for high-risk populations. OBJECTIVES: To investigate the practice, knowledge, and self-perceived barriers for HCC screening among high-risk hospital patients in China. METHODS: An interview-based questionnaire was conducted among Chinese patients with chronic hepatitis B and/or chronic hepatitis C infection from outpatient clinics at 2 tertiary medical institutions in Shanghai and Wuhan, China...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28617908/validation-of-single-c-arm-biplane-fluoroscopy-system-for-in-vivo-measurement-of-porcine-abdominal-strains
#8
Lindsey G Kahan, Charlotte Guertler, Jeffrey A Blatnik, Spencer P Lake
Hernia meshes significantly reduce recurrence rates in hernia repair. It's known that they affect the abdominal wall post-implantation, yet the understanding of in vivo mechanics in the mesh placement area is lacking. We established a single c-arm biplane fluoroscopic system to study strains at the interface between the mesh and repaired abdominal tissues. We aimed to validate this system for future porcine hernia repair studies. Custom MATLAB programs were written to correct for pincushion distortion, and direct linear transformation reconstructed objects in 3D...
June 15, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28611394/identification-of-the-ectoenzyme-cd38-as-a-marker-of-committed-preadipocytes
#9
A Carrière, Y Jeanson, J-A Côté, C Dromard, A Galinier, S Menzel, C Barreau, S Dupuis-Coronas, E Arnaud, A Girousse, V Cuminetti, J Paupert, B Cousin, C Sengenes, F Koch-Nolte, A Tchernof, L Casteilla
BACKGROUND/OBJECTIVES: Characterization of the adipocyte cellular lineage is required for a better understanding of white adipose tissue homeostasis and expansion. While several studies have focused on the phenotype of the most immature adipocyte progenitors, very few tools exist to identify committed cells. In haematopoiesis, the CD38 ectoenzyme is largely used to delineate various stages of stem cell lineage commitment. We hypothesize that this marker could be used to identify committed preadipocytes...
June 14, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28602897/lower-extremity-ischemia-after-abdominal-aortic-aneurysm-repair
#10
C A Behrendt, A Dayama, E S Debus, F Heidemann, N M Matolo, T Kölbel, N Tsilimparis
OBJECTIVE: Treatment reality of abdominal aortic aneurysm (AAA) is changing. Up to date, approximately 65% of intact AAA and 30% of ruptured AAA are treated endovascularly. As most comparative studies focus upon mortality and few major complications, some outcomes as lower extremity ischemia (LEI) after invasive AAA repair are often underreported. However, there is evidence for a worse outcome of patients suffering from this kind of complication. METHODS: Using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) vascular surgery targeted module from 2011 to 2014, we identified all patients undergoing endovascular aortic repair (EVAR) and open aortic repair (OAR) for AAA to illuminate the incidence and outcome of LEI after AAA repair...
June 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28602526/resident-operative-experience-at-independent-academic-medical-centers-a-comparison-to-the-national-cohort
#11
Amit R T Joshi, Amber W Trickey, Benjamin T Jarman, Kara J Kallies, Robert Josloff, Jonathan M Dort, Ravi Kothuru
PURPOSE: Independent Academic Medical Centers (IAMCs) comprise one-third of U.S. general surgery training programs. It is unclear whether IAMCs offer qualitatively or quantitatively different operative experiences than the national cohort. We analyzed a large representative sample of IAMCs to compare operative volume and variety, with a focus on low-volume procedures. METHODS: Accreditation Council for Graduate Medical Education Program Case Reports from 27 IAMCs were collected and analyzed for 3 academic years (2012-2015)...
June 8, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28601334/variation-in-readmission-expenditures-after-high-risk-surgery
#12
Bruce L Jacobs, Chang He, Benjamin Y Li, Alex Helfand, Naveen Krishnan, Tudor Borza, Amir A Ghaferi, Brent K Hollenbeck, Jonathan E Helm, Mariel S Lavieri, Ted A Skolarus
BACKGROUND: The Hospital Readmissions Reduction Program reduces payments to hospitals with excess readmissions for three common medical conditions and recently extended its readmission program to surgical patients. We sought to investigate readmission intensity as measured by readmission cost for high-risk surgeries and examine predictors of higher readmission costs. MATERIALS AND METHODS: We used the Healthcare Cost and Utilization Project's State Inpatient Database to perform a retrospective cohort study of patients undergoing major chest (aortic valve replacement, coronary artery bypass grafting, lung resection) and major abdominal (abdominal aortic aneurysm repair [open approach], cystectomy, esophagectomy, pancreatectomy) surgery in 2009 and 2010...
June 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28593701/comparison-of-efficacy-of-low-carbohydrate-and-low-fat-diet-education-program-in-non-alcoholic-fatty-liver-disease-randomized-controlled-study
#13
Eun Chul Jang, Dae Won Jun, Seung Min Lee, Yong Kyun Cho, Sang Bong Ahn
AIM: Composition of macronutrient is important in nonalcoholic fatty liver disease (NAFLD). Diet education program which mainly emphasize on reducing fat consumption has been used for NAFLD patients. We compared efficacy of conventional low-fat diet education with low-carbohydrate diet education in Korean NAFLD patients. METHODS: One hundred and six NAFLD patients were randomly allocated to low-fat diet education or low-carbohydrate education group for 8 weeks...
June 7, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28593266/wireless-monitoring-program-of-patient-centered-outcomes-and-recovery-before-and-after-major-abdominal-cancer-surgery
#14
Virginia Sun, Sinziana Dumitra, Nora Ruel, Byrne Lee, Laleh Melstrom, Kurt Melstrom, Yanghee Woo, Stephen Sentovich, Gagandeep Singh, Yuman Fong
Importance: A combined subjective and objective wireless monitoring program of patient-centered outcomes can be carried out in patients before and after major abdominal cancer surgery. Objective: To conduct a proof-of-concept pilot study of a wireless, patient-centered outcomes monitoring program before and after major abdominal cancer surgery. Design, Setting, and Participants: In this proof-of-concept pilot study, patients wore wristband pedometers and completed online patient-reported outcome surveys (symptoms and quality of life) 3 to 7 days before surgery, during hospitalization, and up to 2 weeks after discharge...
June 7, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28593090/dynamic-hip-adduction-abduction-and-abdominal-exercises-from-the-holmich-groin-injury-prevention-program-are-intense-enough-to-be-considered-strengthening-exercises-a-cross-sectional-study
#15
Kasper Krommes, Thomas Bandholm, Markus D Jakobsen, Lars L Andersen, Andreas Serner, Per Hölmich, Kristian Thorborg
BACKGROUND: Training intensity is an important variable in strength training and above 80% of one repetition maximum is recommended for promoting strength for athletes. Four dynamic and two isometric on-field exercises are included in the Hölmich groin-injury prevention study that initially failed to show a reduction in groin injuries in soccer players. It has been speculated that exercise-intensity in this groin-injury prevention program was too low to induce the strength gains necessary to protect against groin-related injuries...
June 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28583729/open-abdominal-surgical-training-differences-experienced-by-integrated-vascular-and-general-surgery-residents
#16
Adam Tanious, Mathew Wooster, Andrew Jung, Peter R Nelson, Paul A Armstrong, Murray L Shames
BACKGROUND: As the integrated vascular residency program reaches almost a decade of maturity, a common area of concern among trainees is the adequacy of open abdominal surgical training. It is our belief that although their overall exposure to open abdominal procedures has decreased, integrated vascular residents have an adequate and focused exposure to open aortic surgery during training. METHODS: National operative case log data supplied by the Accreditation Council for Graduate Medical Education were compiled for both graduating integrated vascular surgery residents (IVSRs) and graduating categorical general surgery residents (GSRs) for the years 2012 to 2014...
June 2, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28582821/normal-weight-central-obesity-is-associated-with-metabolic-disorders-in-chinese-postmenopausal-women
#17
Peng Ju Liu, Fang Ma, Hui Ping Lou, Yan Ning Zhu
BACKGROUND AND OBJECTIVES: This cross-sectional study examined whether normal-weight central obesity, defined as a high waist-to-height ratio (WHtR), is associated with metabolic disorders in Chinese postmenopausal women. METHODS AND STUDY DESIGN: We recruited 634 community-dwelling postmenopausal women with a normal body mass index (BMI) who participated in an annual health checkup. Normal-weight obesity (NWO) was defined as a normal BMI and WHtR in the highest tertile of the study population...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28582273/which-knife-was-used-using-a-porcine-model-to-assess-stab-wound-size
#18
Allison Zohn, Judy Melinek
Forensic pathologists who autopsy stab wound victims may be called upon to determine whether a specific weapon recovered as evidence caused the decedent's wounds. Some forensic training programs instruct pathologists to excise wounds and place them in formalin. There is little published information about the reliability of these assessments. To address these deficiencies, a porcine model was used to establish the limits of in situ knife wound measurements of wounds caused by 3 knives of different widths stabbed at 90 degrees to the skin surface...
June 2, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28581026/cross-sectional-association-between-testosterone-sex-hormone-binding-globulin-and-metabolic-syndrome-the-healthy-twin-study
#19
Heesun Moon, Inyoung Choi, Somi Kim, Hyeonyoung Ko, Jinyoung Shin, Kayoung Lee, Joohon Sung, Yun-Mi Song
OBJECTIVES: This study evaluated an association between testosterone, sex hormone-binding globulin (SHBG) and metabolic syndrome (MetS).We also evaluated the genetic and environmental influence on the association. DESIGN: Cross-sectional. SETTING: Community-based study. PARTICIPANTS: A total of 1,098 Korean adult men including 139 monozygotic twin pairs. MAIN OUTCOME MEASURE: MetS was defined using the National Cholesterol Education Program-Third Adult Treatment Panel (NCEP-ATP III) and International Diabetes Federation (IDF) criteria...
June 5, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28580396/combined-aerobic-and-resistance-training-improves-bone-health-of-female-cancer-survivors
#20
Hawley C Almstedt, Silvie Grote, Joshua R Korte, Stephanie Perez Beaudion, Todd C Shoepe, Sarah Strand, Heather P Tarleton
INTRODUCTION: Cancer pathogenesis and resulting treatment may lead to bone loss and poor skeletal health in survivorship. The purpose of this investigation was to evaluate the influence of 26 weeks of combined aerobic and resistance-training (CART) exercise on bone mineral density (BMD) in a multi-racial sample of female cancer survivors. METHODS: Twenty-six female cancer survivors volunteered to undergo CART for 1 h/day, 3 days/week, for 26 weeks. The Improving Physical Activity After Cancer Treatment (IMPAACT) Program involves supervised group exercise sessions including 20 min of cardiorespiratory training, 25 min of circuit-style resistance-training, and 15 min of abdominal exercises and stretching...
December 2016: Bone Reports
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