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VitaminK

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https://www.readbyqxmd.com/read/26877111/-update-on-the-control-of-patients-on-treatment-with-vitamink-antagonist-oral-anticoagulants-in-primary-care
#1
P Fernández López, M I López Ramiro, I Merino de Haro, G Cedeño Manzano, F J Díaz Siles, A Hermoso Sabio
BACKGROUND: In Spain, more than 80% of patients with atrial fibrillation (AF) receive oral anticoagulant therapy (OAT), and 72% of these patients are followed up in the Primary Care (PC) setting. Recent studies have shown that there is insufficient control of patients on OAT. The objective of the present study was to obtain more detailed information on the state of control of patients on treatment with vitaminK antagonist (VKA) oral anticoagulants (OAC), on the diseases for which the therapy was indicated and on concomitant diseases...
February 11, 2016: Semergen
https://www.readbyqxmd.com/read/25192579/-progress-of-anticoagulation-therapy-in-atrial-fibrillation
#2
REVIEW
Miguel Hernández Olmedo, Carmen Suárez Fernández
Atrial fibrillation is currently a very prevalent disease and it represents one of the most common causes of disabling stroke. Antithrombotic therapies have reduced the incidence of this complication although they pose many limitations and difficulties. As a result, a large number of high risk patients do not receive an appropriate treatment. In recent years, four new oral anticoagulants (NOAC) with relevant advantages in comparison to vitaminK antagonists have been released. Four large phaseiii clinical trials have demonstrated that NOAC are at least as safe and efficacious as warfarin in stroke prevention in non-valve atrial fibrillation patients with moderate-high thrombotic risk, being their main advantage the reduction in intracranial hemorrhage...
August 7, 2015: Medicina Clínica
https://www.readbyqxmd.com/read/2076430/the-effect-of-oxidizing-agents-on-cell-division-and-shape
#3
M Tomono, T Urayama
Certain oxidizing agents such as vitaminK(VK) and lipid peroxides were found to suppress an increase in cytoplasmic Ca2+ concentration by growth factors, and inhibit on cell proliferation. These oxidizing agents induced a marked change in cell shape. In a detailed analysis of each phase in the cell cycle, the inhibition of an increase in cytoplasmic Ca2+ and cell division occurred only when the agents were added at G0/G1 phase. The addition to S or M phase cells did not influence in cytoplasmic Ca2+ and cell division...
October 1990: Human Cell
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