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https://www.readbyqxmd.com/read/28633541/the-development-of-a-glucose-dehydrogenase-3d-printed-glucose-sensor-a-proof-of-concept-study
#1
Anngela Adams, Aldin Malkoc, Jeffrey T La Belle
This work represents a preliminary proof-of-concept design and verification of a 3D-printed glucose biosensor. The proof of concept presented is the first example of glucose dehydrogenase sensor fabricated by a 3D-printer while maintaining similar features to current lab-industry standards. The sensor was verified to detect physiological glucose concentrations between 0 and 400 mg/dL with a linear coefficient as high as .97. This study showed that it was possible to use 3D-printed technology to create a biosensor sensitive to glucose detection...
June 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28631418/the-effects-of-biodentine-polycaprolactone-3d-scaffold-with-odontogenesis-properties-on-human-dental-pulp-cells
#2
C-C Ho, H-Y Fang, B Wang, T-H Huang, M-Y Shie
AIM: To determine the feasibility of using three-dimensional printed Biodentine/polycaprolactone composite scaffolds for orthopaedic and dental applications. The physicochemical properties and the odontogenic differentiation of human dental pulp cells (hDPCs) were investigated. METHODOLOGY: Biodentine was well-suspended in ethanol and dropped slowly into molten polycaprolactone with vigorous stirring. The Biodentine/polycaprolactone composite scaffolds were then fabricated into controlled macropore sizes and structures using an extrusion-based three-dimensional (3D) printer...
June 20, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28630927/welding-of-3d-printed-carbon-nanotube-polymer-composites-by-locally-induced-microwave-heating
#3
Charles B Sweeney, Blake A Lackey, Martin J Pospisil, Thomas C Achee, Victoria K Hicks, Aaron G Moran, Blake R Teipel, Mohammad A Saed, Micah J Green
Additive manufacturing through material extrusion, often termed three-dimensional (3D) printing, is a burgeoning method for manufacturing thermoplastic components. However, a key obstacle facing 3D-printed plastic parts in engineering applications is the weak weld between successive filament traces, which often leads to delamination and mechanical failure. This is the chief obstacle to the use of thermoplastic additive manufacturing. We report a novel concept for welding 3D-printed thermoplastic interfaces using intense localized heating of carbon nanotubes (CNTs) by microwave irradiation...
June 2017: Science Advances
https://www.readbyqxmd.com/read/28628294/fused-deposition-modeling-3d-printing-for-bio-analytical-device-fabrication-procedures-materials-and-applications
#4
Gert Ij Salentijn, Pieter E Oomen, Maciej Grajewski, Elisabeth Verpoorte
In this work, the use of fused deposition modeling (FDM) in a (bio)analytical/lab-on-a-chip research laboratory is described. First, the specifications of this 3D printing method that are important for the fabrication of (micro)devices were characterized for a benchtop FDM 3D printer. These include resolution, surface roughness, leakage, transparency, material deformation, and the possibilities for integration of other materials. Next, the autofluorescence, solvent compatibility, and biocompatibility of 12 representative FDM materials were tested and evaluated...
June 19, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28619543/circumferential-three-dimensional-printed-tracheal-grafts-research-model-feasibility-and-early-results
#5
Faiz Y Bhora, Erik E Lewis, Sadiq S Rehmani, Adil Ayub, Wissam Raad, Adnan M Al-Ayoubi, Robert S Lebovics
BACKGROUND: Methods for tracheal graft research have presented persistent challenges to investigators, and three-dimensional (3D)-printed biosynthetic grafts offer one potential development platform. We aimed to develop an efficient research platform for customizable circumferential 3D-printed tracheal grafts and evaluate feasibility and early structural integrity with a large-animal model. METHODS: Virtual 3D models of porcine subject tracheas were generated using preoperative computed tomography scans...
June 13, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28612085/moving-from-millifluidic-to-truly-microfluidic-sub-100-%C3%AE-m-cross-section-3d-printed-devices
#6
Michael J Beauchamp, Gregory P Nordin, Adam T Woolley
Three-dimensional (3D) printing has generated considerable excitement in recent years regarding the extensive possibilities of this enabling technology. One area in which 3D printing has potential, not only for positive impact but also for substantial improvement, is microfluidics. To date many researchers have used 3D printers to make fluidic channels directed at point-of-care or lab-on-a-chip applications. Here, we look critically at the cross-sectional sizes of these 3D printed fluidic structures, classifying them as millifluidic (larger than 1 mm), sub-millifluidic (0...
July 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28610691/radiological-properties-of-3d-printed-materials-in-kilovoltage-and-megavoltage-photon-beams
#7
O L Dancewicz, S R Sylvander, T S Markwell, S B Crowe, J V Trapp
PURPOSE: This study evaluates the radiological properties of different 3D printing materials for a range of photon energies, including kV and MV CT imaging and MV radiotherapy beams. METHODS: The CT values of a number of materials were measured on an Aquilion One CT scanner at 80kVp, 120kVp and a Tomotherapy Hi Art MVCT imaging beam. Attenuation of the materials in a 6MV radiotherapy beam was investigated. RESULTS: Plastic filaments printed with various infill densities have CT values of -743±4, -580±1 and -113±3 in 120kVp CT images which approximate the CT values of low-density lung, high-density lung and soft tissue respectively...
June 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28587563/how-precise-are-preinterventional-measurements-using-centerline-analysis-applications-objective-ground-truth-evaluation-reveals-software-specific-centerline-characteristics
#8
Philipp Hoegen, Stefan Wörz, Matthias Müller-Eschner, Philipp Geisbüsch, Wei Liao, Karl Rohr, Matthias Schmitt, Fabian Rengier, Hans-Ulrich Kauczor, Hendrik von Tengg-Kobligk
PURPOSE: To evaluate different centerline analysis applications using objective ground truth from realistic aortic aneurysm phantoms with precisely defined geometry and centerlines to overcome the lack of unknown true dimensions in previously published in vivo validation studies. METHODS: Three aortic phantoms were created using computer-aided design (CAD) software and a 3-dimensional (3D) printer. Computed tomography angiograms (CTAs) of phantoms and 3 patients were analyzed with 3 clinically approved and 1 research software application...
June 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28586401/3d-printing-and-milling-a-real-time-pcr-device-for-infectious-disease-diagnostics
#9
Geoffrey Mulberry, Kevin A White, Manjusha Vaidya, Kiminobu Sugaya, Brian N Kim
Diagnosing infectious diseases using quantitative polymerase chain reaction (qPCR) offers a conclusive result in determining the infection, the strain or type of pathogen, and the level of infection. However, due to the high-cost instrumentation involved and the complexity in maintenance, it is rarely used in the field to make a quick turnaround diagnosis. In order to provide a higher level of accessibility than current qPCR devices, a set of 3D manufacturing methods is explored as a possible option to fabricate a low-cost and portable qPCR device...
2017: PloS One
https://www.readbyqxmd.com/read/28584246/micro-drive-and-headgear-for-chronic-implant-and-recovery-of-optoelectronic-probes
#10
Jinho Chung, Farnaz Sharif, Dajung Jung, Soyoun Kim, Sebastien Royer
Silicon probes are multisite electrodes used for the electrophysiological recording of large neuronal ensembles. Optoelectronic probes (OEPs) are recent upgrades that allow, in parallel, the delivery of local optical stimuli. The procedures to use these delicate electrodes for chronic experiments in mice are still underdeveloped and typically assume one-time uses. Here, we developed a micro-drive, a support for OEPs optical fibers, and a hat enclosure, which fabrications consist in fitting and fastening together plastic parts made with 3D printers...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28578984/comparison-of-dimensional-accuracy-of-conventionally-and-digitally-manufactured-intracoronal-restorations
#11
Reza Eftekhar Ashtiani, Leila Nasiri Khanlar, Minoo Mahshid, Alireza Moshaverinia
STATEMENT OF PROBLEM: Advances have been made in digital dentistry for the fabrication of dental prostheses, but evidence regarding the efficacy of digital techniques for the fabrication of intracoronal restorations is lacking. PURPOSE: The purpose of this in vitro study was to compare the dimensional accuracy of intracoronal restorations fabricated with digital and conventional techniques. MATERIAL AND METHODS: A sound mandibular molar tooth received a standard onlay preparation, and onlays were fabricated with 1 of 3 fabrication techniques...
June 2, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28562693/from-medical-imaging-data-to-3d-printed-anatomical-models
#12
Thore M Bücking, Emma R Hill, James L Robertson, Efthymios Maneas, Andrew A Plumb, Daniil I Nikitichev
Anatomical models are important training and teaching tools in the clinical environment and are routinely used in medical imaging research. Advances in segmentation algorithms and increased availability of three-dimensional (3D) printers have made it possible to create cost-efficient patient-specific models without expert knowledge. We introduce a general workflow that can be used to convert volumetric medical imaging data (as generated by Computer Tomography (CT)) to 3D printed physical models. This process is broken up into three steps: image segmentation, mesh refinement and 3D printing...
2017: PloS One
https://www.readbyqxmd.com/read/28559498/3d-printers-provide-a-window-into-the-heart
#13
Bridget M Kuehn
No abstract text is available yet for this article.
May 30, 2017: Circulation
https://www.readbyqxmd.com/read/28554463/accuracy-of-printed-dental-models-made-with-2-prototype-technologies-and-different-designs-of-model-bases
#14
Leonardo Tavares Camardella, Oswaldo de Vasconcellos Vilella, Hero Breuning
INTRODUCTION: The aim of this study was to compare the accuracy of printed models from intraoral scans with different designs of model bases, using 2 types of 3-dimensional printing techniques. METHODS: Three types of model base design were created: regular base, horseshoe-shaped base, and horseshoe-shaped base with a bar connecting the posterior region. The digital models were printed with the 3-dimensional printers using different techniques: stereolithography and triple jetting technology (polyjet)...
June 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28552791/three-dimensional-printing-technologies-applications-and-limitations-in-neurosurgery
#15
REVIEW
Josephine U Pucci, Brandon R Christophe, Jonathan A Sisti, Edward S Connolly
Three-dimensional (3D) printers are a developing technology penetrating a variety of markets, including the medical sector. Since its introduction to the medical field in the late 1980s, 3D printers have constructed a range of devices, such as dentures, hearing aids, and prosthetics. With the ultimate goals of decreasing healthcare costs and improving patient care and outcomes, neurosurgeons are utilizing this dynamic technology, as well. Digital Imaging and Communication in Medicine (DICOM) can be translated into Stereolithography (STL) files, which are then read and methodically built by 3D Printers...
May 24, 2017: Biotechnology Advances
https://www.readbyqxmd.com/read/28541035/three-dimensional-printing-of-silver-microarchitectures-using-newtonian-nanoparticle-inks
#16
Sanghyeon Lee, Jung Hyun Kim, Muhammad Wajahat, Hwakyung Jeong, Won Suk Chang, Sung Ho Cho, Ji Tae Kim, Seung Kwon Seol
Although three-dimensional (3D) printing has recently emerged as a technology to potentially bring about the next industrial revolution, the limited selection of usable materials restricts its use to simple prototyping. In particular, metallic 3D printing with submicrometer spatial resolution is essential for the realization of 3D-printed electronics. Herein, a meniscus-guided 3D printing method that exploits a low-viscosity (∼7 mPa·s) silver nanoparticle (AgNP) ink meniscus with Newtonian fluid characteristics (which is compatible with conventional inkjet printers) to fabricate 3D silver microarchitectures is reported...
June 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28530209/reproducible-3d-printed-head-tanks-for-electrical-impedance-tomography-with-realistic-shape-and-conductivity-distribution
#17
James Avery, Kirill Aristovich, Barney Low, David Holder
OBJECTIVE: Electrical impedance tomography (EIT) has many promising applications in brain injury monitoring. To evaluate both instrumentation and reconstruction algorithms, experiments are first performed in head tanks. Existing methods, whilst accurate, produce a discontinuous conductivity, and are often made by hand, making it hard for other researchers to replicate. APPROACH: We have developed a method for constructing head tanks directly in a 3D printer. Conductivity was controlled through perforations in the skull surface, which allow for saline to pass through...
May 22, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28520846/patient-specific-augmentation-rhinoplasty-using-a-three-dimensional-simulation-program-and-three-dimensional-printing
#18
Yim Don Choi, Youngjun Kim, EunSoo Park
Background: The convergence of three-dimensional (3D) simulation, tissue engineering, and 3D printing technology is creating a paradigm shift in plastic surgery. In augmentation rhinoplasty, determining the ideal material and design method has been a critical issue for many years. Thus, these technologies are expected to make important contributions to augmentation rhinoplasty. Objectives: We sought to validate the feasibility of the 3D carving simulation and patient-specific implant fabrication system (3D carving system) in a clinical trial using reproducibility tests...
May 17, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28518077/inkjet-printed-polyvinyl-alcohol-multilayers
#19
Iulia Salaoru, Zuoxin Zhou, Peter Morris, Gregory J Gibbons
Inkjet printing is a modern method for polymer processing, and in this work, we demonstrate that this technology is capable of producing polyvinyl alcohol (PVOH) multilayer structures. A polyvinyl alcohol aqueous solution was formulated. The intrinsic properties of the ink, such as surface tension, viscosity, pH, and time stability, were investigated. The PVOH-based ink was a neutral solution (pH 6.7) with a surface tension of 39.3 mN/m and a viscosity of 7.5 cP. The ink displayed pseudoplastic (non-Newtonian shear thinning) behavior at low shear rates, and overall, it demonstrated good time stability...
May 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28513626/fabrication-of-cerebral-aneurysm-simulator-with-a-desktop-3d-printer
#20
Yu Liu, Qing Gao, Song Du, ZiChen Chen, JianZhong Fu, Bing Chen, ZhenJie Liu, Yong He
Now, more and more patients are suffering cerebral aneurysm. However, long training time limits the rapid growth of cerebrovascular neurosurgeons. Here we developed a novel cerebral aneurysm simulator which can be better represented the dynamic bulging process of cerebral aneurysm The proposed simulator features the integration of a hollow elastic vascular model, a skull model and a brain model, which can be affordably fabricated at the clinic (Fab@Clinic), under $25.00 each with the help of a low-cost desktop 3D printer...
May 17, 2017: Scientific Reports
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