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https://www.readbyqxmd.com/read/29690761/printing-of-patterned-engineered-e-coli-biofilms-with-a-low-cost-3d-printer
#1
Dominik Tobias Schmieden, Samantha J Basalo Vázquez, Hector Sangüesa, Marit van der Does, Timon Idema, Anne Sara Meyer
Biofilms can grow on virtually any surface available, with impacts ranging from endangering the lives of patients to degrading unwanted water contaminants. Biofilm research is challenging due to the high degree of biofilm heterogeneity. A method for the production of standardized, reproducible, and patterned biofilm-inspired materials could be a boon for biofilm research and allow for completely new engineering applications. Here, we present such a method, combining 3D printing with genetic engineering. We prototyped a low-cost 3D printer that prints bioink, a suspension of bacteria in a solution of alginate that solidifies on a calcium-containing substrate...
April 24, 2018: ACS Synthetic Biology
https://www.readbyqxmd.com/read/29690641/intelligent-fault-diagnosis-of-delta-3d-printers-using-attitude-sensors-based-on-support-vector-machines
#2
Kun He, Zhijun Yang, Yun Bai, Jianyu Long, Chuan Li
Health condition is a vital factor affecting printing quality for a 3D printer. In this work, an attitude monitoring approach is proposed to diagnose the fault of the delta 3D printer using support vector machines (SVM). An attitude sensor was mounted on the moving platform of the printer to monitor its 3-axial attitude angle, angular velocity, vibratory acceleration and magnetic field intensity. The attitude data of the working printer were collected under different conditions involving 12 fault types and a normal condition...
April 23, 2018: Sensors
https://www.readbyqxmd.com/read/29688690/three-dimensionally-printed-microelectromechanical-switches
#3
Yongwoo Lee, Jungmin Han, Bongsik Choi, Jinsu Yoon, Jinhee Park, Yeamin Kim, Jieun Lee, Dae Hwan Kim, Dong Myong Kim, Meehyun Lim, Min-Ho Kang, Sungho Kim, Sung-Jin Choi
Three-dimensional (3D) printers have attracted considerable attention from both industry and academia and especially in recent years due to their ability to overcome the limitations of two-dimensional (2D) processes and to enable large-scale facile integration techniques. With 3D printing technologies, complex structures can be created using only a computer-aided design (CAD) file as a reference; consequently, complex shapes can be manufactured in a single step with little dependence on manufacturer technologies...
April 24, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29684169/characterization-and-performance-tests-of-a-new-osl-tl-personal-dosemeter-for-individual-monitoring
#4
A L M C Malthez, E M Yoshimura, V L S N Button, M B Freitas
We propose a personal dosemeter based on the combination of thermoluminescence (TL) and optically stimulated luminescence (OSL) detectors employing the advantages of both techniques. The new OSL/TL dosemeter using a badge manufactured in a 3D printer was tested for assessment of photon doses in simulated and actual situations of exposure. Additionally, Brazilian national performance tests adapted to the new dosemeter were run as well as the performance tests of international standards on the passive dosimetry systems...
April 19, 2018: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29680281/multi-purposable-filaments-of-hpmc-for-3d-printing-of-medications-with-tailored-drug-release-and-timed-absorption
#5
Hossam Kadry, Taslim A Al-Hilal, Ali Keshavarz, Farzana Alam, Changxue Xu, Abraham Joy, Fakhrul Ahsan
Three-dimensional printing (3DP), though developed for nonmedical applications and once regarded as futuristic only, has recently been deployed for the fabrication of pharmaceutical products. However, the existing feeding materials (inks and filaments) that are used for printing drug products have various shortcomings, including the lack of biocompatibility, inadequate extrudability and printability, poor drug loading, and instability. Here, we have sought to develop a filament using a single pharmaceutical polymer, with no additives, which can be multi-purposed and manipulated by computational design for the preparation of tablets with desired release and absorption patterns...
April 19, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29671367/3d-bio-printing-technology-for-body-tissues-and-organs-regeneration
#6
Esmaeil Biazar, Masoumeh Najafi S, Saeed Heidari K, Meysam Yazdankhah, Ataollah Rafiei, Dariush Biazar
In the last decade, the use of new technologies in the reconstruction of body tissues has greatly developed. Utilising stem cell technology, nanotechnology and scaffolding design has created new opportunities in tissue regeneration. The use of accurate engineering design in the creation of scaffolds, including 3D printers, has been widely considered. Three-dimensional printers, especially high precision bio-printers, have opened up a new way in the design of 3D tissue engineering scaffolds. In this article, a review of the latest applications of this technology in this promising area has been addressed...
April 19, 2018: Journal of Medical Engineering & Technology
https://www.readbyqxmd.com/read/29658700/3d-printed-graphene-polylactic-acid-electrodes-promise-high-sensitivity-in-electroanalysis
#7
C Lorena Manzanares Palenzuela, Filip Novotný, Petr Krupička, Zdeněk Sofer, Martin Pumera
Additive manufacturing provides a unique tool for prototyping structures toward electrochemical sensing, due to its ability to produce highly versatile, tailored-shaped devices in a low-cost and fast way with minimized waste. Here we present 3D-printed graphene electrodes for electrochemical sensing. Ring- and disc-shaped electrodes were 3D-printed with a Fused Deposition Modeling printer and characterized using cyclic voltammetry and scanning electron microscopy. Different redox probes K3 Fe(CN)6 :K4 Fe(CN)6 , FeCl3 , ascorbic acid, Ru(NH3 )6 Cl3 , and ferrocene monocarboxylic acid) were used to assess the electrochemical performance of these devices...
April 16, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29656459/desktop-stereolithography-3d-printing-of-a-poly-dimethylsiloxane-based-material-with-sylgard-184-properties
#8
Nirveek Bhattacharjee, Cesar Parra-Cabrera, Yong Tae Kim, Alexandra P Kuo, Albert Folch
The advantageous physiochemical properties of poly(dimethylsiloxane) (PDMS) have made it an extremely useful material for prototyping in various technological, scientific, and clinical areas. However, PDMS molding is a manual procedure and requires tedious assembly steps, especially for 3D designs, thereby limiting its access and usability. On the other hand, automated digital manufacturing processes such as stereolithography (SL) enable true 3D design and fabrication. Here the formulation, characterization, and SL application of a 3D-printable PDMS resin (3DP-PDMS) based on commercially available PDMS-methacrylate macromers, a high-efficiency photoinitiator and a high-absorbance photosensitizer, is reported...
April 14, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29615324/comparing-the-accuracy-trueness-and-precision-of-models-of-fixed-dental-prostheses-fabricated-by-digital-and-conventional-workflows
#9
Ji-Young Sim, Yeon Jang, Woong-Chul Kim, Hae-Young Kim, Dong-Hwan Lee, Ji-Hwan Kim
PURPOSE: This study aimed to evaluate and compare the accuracy. METHODS: A reference model was prepared with three prepared teeth for three types of restorations: single crown, 3-unit bridge, and inlay. Stone models were fabricated from conventional impressions. Digital impressions of the reference model were created using an intraoral scanner (digital models). Physical models were fabricated using a three-dimensional (3D) printer. Reference, stone, and 3D printed models were subsequently scanned using an industrial optical scanner; files were exported in a stereolithography file format...
March 31, 2018: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/29608267/additive-manufacturing-of-catalytically-active-living-materials
#10
Abhijit Saha, Trevor G Johnston, Ryan T Shafranek, Cassandra J Goodman, Jesse G Zalatan, Duane W Storti, Mark A Ganter, Alshakim Nelson
Living materials, which are composites of living cells residing in a polymeric matrix, are designed to utilize the innate functionalities of the cells to address a broad range of applications such as fermentation and biosensing. Herein, we demonstrate the additive manufacturing of catalytically active living materials (AMCALM) for continuous fermentation. A multi-stimuli-responsive yeast-laden hydrogel ink-based on F127-dimethacrylate-was developed and printed using a direct-write 3D printer. The reversible stimuli-responsive behaviors of the polymer hydrogel inks to temperature and pressure are critical, as they enabled the facile incorporation of yeast cells and subsequent fabrication of 3D lattice constructs...
April 2, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29607200/initial-experience-with-a-3d-printed-model-for-preoperative-simulation-of-the-nuss-procedure-for-pectus-excavatum
#11
Naoto Matsuo, Keitaro Matsumoto, Yasuaki Taura, Yuka Sakakibara, Daisuke Taniguchi, Katsunori Takagi, Yusuke Yamane, Masayuki Obatake, Naoya Yamasaki, Takeshi Nagayasu
The incidence of pectus excavatum has been estimated to be between 0.1% and 0.8% though a large autopsy series reports. After publication of the Nuss procedure for pectus excavatum, it became widely accepted. However, there are still some complications, such as over-correction and recurrence. To reduce differences in the procedure due to surgeons' experience level, preoperative simulation may be useful. Thus, we performed simulated surgery using a specific patient's three-dimensional (3D) chest wall model made by a 3D printer before operation...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29607159/application-of-3d-printing-in-the-surgical-planning-of-hypertrophic-obstructive-cardiomyopathy-and-physician-patient-communication-a-preliminary-study
#12
Hong-Chang Guo, Yang Wang, Jiang Dai, Chang-Wei Ren, Jin-Hua Li, Yong-Qiang Lai
Background: The aim of this study was to evaluate the effect of 3-dimensional (3D) printing in treatment of hypertrophic obstructive cardiomyopathy (HOCM) and its roles in doctor-patient communication. Methods: 3D-printed models were constructed preoperatively and postoperatively in seven HOCM patients received surgical treatment. Based on multi-slice computed tomography (CT) images, regions of disorder were segmented using the Mimics 19.0 software (Materialise, Leuven, Belgium)...
February 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29605694/pharmaceutical-3d-printing-design-and-qualification-of-a-single-step-print-and-fill-capsule
#13
Derrick M Smith, Yash Kapoor, Gerard R Klinzing, Adam T Procopio
Fused deposition modeling 3D printing (3DP) has a potential to change how we envision manufacturing in the pharmaceutical industry. A more common utilization for FDM is to build upon existing hot melt extrusion technology where the drug is dispersed in the polymer matrix. However, reliable manufacturing of drug-containing FDM filaments remains a challenge along with the limitation of active ingredients which can sustain the processing risks involved in the HME process. To circumvent this obstacle, a single step FDM process was developed to manufacture thin-walled drug-free capsules which can be filled with dry or liquid drug product formulations...
March 29, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29605693/defined-drug-release-from-3d-printed-composite-tablets-consisting-of-drug-loaded-polyvinylalcohol-and-a-water-soluble-or-water-insoluble-polymer-filler
#14
Tatsuaki Tagami, Noriko Nagata, Naomi Hayashi, Emi Ogawa, Kaori Fukushige, Norihito Sakai, Tetsuya Ozeki
3D-printed tablets are a promising new approach for personalized medicine. In this study, we fabricated composite tablets consisting of two components, a drug and a filler, by using a fused deposition modeling-type 3D printer. Polyvinylalcohol (PVA) polymer containing calcein (a model drug) was used as the drug component and PVA or polylactic acid (PLA) polymer without drug was used as the water-soluble or water-insoluble filler, respectively. Various kinds of drug-PVA/PVA and drug-PVA/PLA composite tablets were designed, and the 3D-printed tablets exhibited good formability...
March 29, 2018: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29602152/how-to-recognize-the-traces-left-on-a-crime-scene-by-a-3d-printed-liberator-part-1-discharge-exterior-ballistic-and-wounding-potential
#15
Hanna Honsberger, Damien Rhumorbarbe, Denis Werner, Fabiano Riva, Matthieu Glardon, Alain Gallusser, Olivier Delémont
The Liberator is a firearm that can be manufactured from its blueprints, using a 3D-printer. This weapon made of nineteen pieces - eighteen in printed plastic and one metallic nail - raises questions such as its ability to fire a round, its wounding potential and the traces produced by its discharge. In particular, knowledge must be gained to infer that a 3D-printed handgun was used, reconstruct the shooting event involving such handgun, and gather information related to the type of 3D-printed handgun used...
May 2018: Forensic Science International
https://www.readbyqxmd.com/read/29596418/accessing-microfluidics-through-feature-based-design-software-for-3d-printing
#16
Peter G Shankles, Larry J Millet, Jayde A Aufrecht, Scott T Retterer
Additive manufacturing has been a cornerstone of the product development pipeline for decades, playing an essential role in the creation of both functional and cosmetic prototypes. In recent years, the prospects for distributed and open source manufacturing have grown tremendously. This growth has been enabled by an expanding library of printable materials, low-cost printers, and communities dedicated to platform development. The microfluidics community has embraced this opportunity to integrate 3D printing into the suite of manufacturing strategies used to create novel fluidic architectures...
2018: PloS One
https://www.readbyqxmd.com/read/29595787/four-in-one-3d-printer-paves-way-for-custom-made-robots-and-phones
#17
Mark Zastrow
No abstract text is available yet for this article.
March 29, 2018: Nature
https://www.readbyqxmd.com/read/29576649/error-analysis-how-precise-is-fused-deposition-modeling-in-fabrication-of-bone-models-in-comparison-to-the-parent-bones
#18
M V Reddy, Krishnakiran Eachempati, A V Gurava Reddy, Aakash Mugalur
Background: Rapid prototyping (RP) is used widely in dental and faciomaxillary surgery with anecdotal uses in orthopedics. The purview of RP in orthopedics is vast. However, there is no error analysis reported in the literature on bone models generated using office-based RP. This study evaluates the accuracy of fused deposition modeling (FDM) using standard tessellation language (STL) files and errors generated during the fabrication of bone models. Materials and Methods: Nine dry bones were selected and were computed tomography (CT) scanned...
March 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29575596/verification-of-acuros-xb-dose-algorithm-using-3d-printed-low-density-phantoms-for-clinical-photon-beams
#19
Rodolfo Zavan, Philip McGeachy, Joseph Madamesila, Jose-Eduardo Villarreal-Barajas, Rao Khan
The transport-based dose calculation algorithm Acuros XB (AXB) has been shown to accurately account for heterogeneities primarily through comparisons with Monte Carlo simulations. This study aims to provide additional experimental verification of AXB for clinically relevant flattened and unflattened beam energies in low density phantoms of the same material. Polystyrene slabs were created using a bench-top 3D printer. Six slabs were printed at varying densities from 0.23 to 0.68 g/cm3 , corresponding to different density humanoid tissues...
March 25, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29569667/a-3d-printed-flow-distributor-with-uniform-flow-rate-control-for-multi-stacked-microfluidic-systems
#20
Young-June Park, Taejong Yu, Se-Jun Yim, Donghyun You, Dong-Pyo Kim
In the scale-up of chemical production in a microfluidic system, it is challenging to prevent flow maldistribution from a single inlet into stacked multiple microchannel exits. In the present study, a compact flow distributor equipped with a fluidic damper is developed by computational fluid dynamics (CFD) along with experimental validation. A microfluidic flow distributor, which is equipped with an optimized fluidic damper and consists of 25 exit channels, is fabricated as an integrated body using a digital light processing (DLP) type 3D printer...
March 23, 2018: Lab on a Chip
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