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https://www.readbyqxmd.com/read/27920950/on-the-intrinsic-sterility-of-3d-printing
#1
Russell Y Neches, Kaitlin J Flynn, Luis Zaman, Emily Tung, Nicholas Pudlo
3D printers that build objects using extruded thermoplastic are quickly becoming commonplace tools in laboratories. We demonstrate that with appropriate handling, these devices are capable of producing sterile components from a non-sterile feedstock of thermoplastic without any treatment after fabrication. The fabrication process itself results in sterilization of the material. The resulting 3D printed components are suitable for a wide variety of applications, including experiments with bacteria and cell culture...
2016: PeerJ
https://www.readbyqxmd.com/read/27918636/4d-printing-of-shape-memory-based-personalized-endoluminal-medical-devices
#2
Matt Zarek, Nicola Mansour, Shir Shapira, Daniel Cohn
The convergence of additive manufacturing and shape-morphing materials is promising for the advancement of personalized medical devices. The capability to transform 3D objects from one shape to another, right off the print bed, is known as 4D printing. Shape memory thermosets can be tailored to have a range of thermomechanical properties favorable to medical devices, but processing them is a challenge because they are insoluble and do not flow at any temperature. This study presents here a strategy to capitalize on a series of medical imaging modalities to construct a printable shape memory endoluminal device, exemplified by a tracheal stent...
December 5, 2016: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/27917703/principles-of-the-kenzan-method-for-robotic-cell-spheroid-based-3d-bioprinting
#3
Nicanor I Moldovan, Narutoshi Hibino, Koichi Nakayama
Bioprinting is a technology with the prospect to change the way many diseases are treated, by replacing the damaged tissues with live, de novo created bio-similar constructs. However, after more than a decade of incubation and many proofs-of-concept, the field is still in its infancy. The current stagnation is the consequence of its early success: the first bioprinters, and most of those which followed, were modified versions of the 3D printers used in additive manufacturing, redesigned for layer-by-layer dispersion of biomaterials...
December 4, 2016: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/27908164/comparison-of-low-contrast-detectability-between-two-ct-reconstruction-algorithms-using-voxel-based-3d-printed-textured-phantoms
#4
Justin Solomon, Alexandre Ba, François Bochud, Ehsan Samei
PURPOSE: To use novel voxel-based 3D printed textured phantoms in order to compare low-contrast detectability between two reconstruction algorithms, FBP (filtered-backprojection) and SAFIRE (sinogram affirmed iterative reconstruction) and determine what impact background texture (i.e., anatomical noise) has on estimating the dose reduction potential of SAFIRE. METHODS: Liver volumes were segmented from 23 abdominal CT cases. The volumes were characterized in terms of texture features from gray-level co-occurrence and run-length matrices...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27906687/economic-3d-printing-approach-for-transplantation-of-human-stem-cell-derived-%C3%AE-like-cells
#5
Jiwon Song, Jeffrey R Millman
Transplantation of human pluripotent stem cells (hPSC) differentiated into insulin-producing β cells is a regenerative medicine approach being investigated for diabetes cell replacement therapy. This report presents a multifaceted transplantation strategy that combines differentiation into stem cell-derived β (SC-β) cells with 3D printing. By modulating the parameters of a low-cost 3D printer, we created a macroporous device composed of polylactic acid (PLA) that houses SC-β cell clusters within a degradable fibrin gel...
December 1, 2016: Biofabrication
https://www.readbyqxmd.com/read/27906236/drawing-optical-fibers-from-three-dimensional-printers
#6
John Canning, Md Arafat Hossain, Chunyang Han, Loic Chartier, Kevin Cook, Tristan Athanaze
The temperature distribution within extrusion nozzles of three low-cost desktop 3D printers is characterized using fiber Bragg gratings (FBGs) to assess their compatibility as micro-furnaces for optical fiber and taper production. These profiles show remarkably consistent distributions suitable for direct drawing of optical fiber. As proof of principle, coreless optical fibers (φ=30  μm) made from fluorinated acrylonitrile butadiene styrene (ABS) and polyethylene terephthalate glycol (PETG) are drawn...
December 1, 2016: Optics Letters
https://www.readbyqxmd.com/read/27903193/three-dimensional-assessment-of-the-effects-of-high-density-embolization-material-on-the-absorbed-dose-in-the-target-for-gamma-knife-radiosurgery-of-arteriovenous-malformations
#7
Yoichi Watanabe, Divyajot Sandhu, Leighton Warmington, Sean Moen, Ramachandra Tummala
OBJECTIVE Arteriovenous malformation (AVM) is an intracranial vascular disorder. Gamma Knife radiosurgery (GKRS) is used in conjunction with intraarterial embolization to eradicate the nidus of AVMs. Clinical results indicate that patients with prior embolization tend to gain less benefit from GKRS. The authors hypothesized that this was partly caused by dosimetric deficiency. The actual dose delivered to the target may be smaller than the intended dose because of increased photon attenuation by high-density embolic materials...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27892655/3d-printed-polycaprolactone-carbon-nanotube-composite-scaffolds-for-cardiac-tissue-engineering
#8
Chee Meng Benjamin Ho, Abhinay Mishra, Pearlyn Teo Pei Lin, Sum Huan Ng, Wai Yee Yeong, Young-Jin Kim, Yong-Jin Yoon
Fabrication of tissue engineering scaffolds with the use of novel 3D printing has gained lot of attention, however systematic investigation of biomaterials for 3D printing have not been widely explored. In this report, well-defined structures of polycaprolactone (PCL) and PCL- carbon nanotube (PCL-CNT) composite scaffolds have been designed and fabricated using a 3D printer. Conditions for 3D printing has been optimized while the effects of varying CNT percentages with PCL matrix on the thermal, mechanical and biological properties of the printed scaffolds are studied...
November 28, 2016: Macromolecular Bioscience
https://www.readbyqxmd.com/read/27892505/in-vivo-measurement-of-hemodynamic-information-in-stenosed-rat-blood-vessels-using-x-ray-piv
#9
Hanwook Park, Jun Hong Park, Sang Joon Lee
Measurements of the hemodynamic information of blood flows, especially wall shear stress (WSS), in animal models with circulatory vascular diseases (CVDs) are important to understand the pathological mechanism of CVDs. In this study, X-ray particle image velocimetry (PIV) with high spatial resolution was applied to obtain velocity field information in stenosed blood vessels with high WSS. 3D clips fabricated with a 3D printer were applied to the abdominal aorta of a rat cadaver to induce artificial stenosis in the real blood vessel of an animal model...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27886051/a-laminar-flow-based-microfluidic-tesla-pump-via-lithography-enabled-3d-printing
#10
Mohammed-Baker Habhab, Tania Ismail, Joe Fujiou Lo
Tesla turbine and its applications in power generation and fluid flow were demonstrated by Nicholas Tesla in 1913. However, its real-world implementations were limited by the difficulty to maintain laminar flow between rotor disks, transient efficiencies during rotor acceleration, and the lack of other applications that fully utilize the continuous flow outputs. All of the aforementioned limits of Tesla turbines can be addressed by scaling to the microfluidic flow regime. Demonstrated here is a microscale Tesla pump designed and fabricated using a Digital Light Processing (DLP) based 3D printer with 43 µm lateral and 30 µm thickness resolutions...
November 23, 2016: Sensors
https://www.readbyqxmd.com/read/27876267/open-wedge-high-tibial-osteotomy-using-three-dimensional-printed-models-experimental-analysis-using-porcine-bone
#11
Jun-Dae Kwun, Hee-June Kim, Jaeyoung Park, Il-Hyung Park, Hee-Soo Kyung
BACKGROUND: The purpose of this study was to evaluate the usefulness of three-dimensional (3D) printed models for open wedge high tibial osteotomy (HTO) in porcine bone. METHODS: Computed tomography (CT) images were obtained from 10 porcine knees and 3D imaging was planned using the 3D-Slicer program. The osteotomy line was drawn from the three centimeters below the medial tibial plateau to the proximal end of the fibular head. Then the osteotomy gap was opened until the mechanical axis line was 62...
November 18, 2016: Knee
https://www.readbyqxmd.com/read/27843644/effect-of-three-dimensional-printed-personalized-moisture-chamber-spectacles-on-the-periocular-humidity
#12
Chan Hee Moon, Jae Yong Kim, Myoung Joon Kim, Hungwon Tchah, Byeong Gak Lim, Jin Kwon Chung
Purpose. To assess the effect of three-dimensional (3D) printed personalized moisture chamber spectacles (PMCS) on the periocular humidity. Methods. Facial computed tomography (CT) scanning was conducted on 10 normal subjects. PMCS was designed based on volume rendered CT images and produced using a 3D printer. Periocular humidity of PMCS and commercially available uniformed moisture chamber spectacles (UMCS) were measured for 30 minutes via microhydrometer. Results. The mean ambient humidity was 15.76 ± 1...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27834416/accuracy-and-efficiency-of-full-arch-digitalization-and-3d-printing-a-comparison-between-desktop-model-scanners-an-intraoral-scanner-a-cbct-model-scan-and-stereolithographic-3d-printing
#13
Christian Wesemann, Jonas Muallah, James Mah, Axel Bumann
OBJECTIVE: The primary objective of this study was to compare the accuracy and time efficiency of an indirect and direct digitalization workflow with that of a three-dimensional (3D) printer in order to identify the most suitable method for orthodontic use. METHOD AND MATERIALS: A master model was measured with a coordinate measuring instrument. The distances measured were the intercanine width, the intermolar width, and the dental arch length. Sixty-four scans were taken with each of the desktop scanners R900 and R700 (3Shape), the intraoral scanner TRIOS Color Pod (3Shape), and the Promax 3D Mid cone beam computed tomography (CBCT) unit (Planmeca)...
November 10, 2016: Quintessence International
https://www.readbyqxmd.com/read/27828340/design-method-for-broadband-free-space-electromagnetic-cloak-based-on-isotropic-material-for-size-reduction-and-enhanced-invisibility
#14
Yongjune Kim, Ilsung Seo, Il-Suek Koh, Yongshik Lee
A design method is proposed that not only improves the invisibility of but also minimizes the size of a two-dimensional (2D) free-space electromagnetic cloak based on the quasi-conformal mapping (QCM) technique. The refractive index profile of the cloak based on the QCM is optimally scaled to minimize performance deterioration due to the imperfect isotropy of the cloak medium. Moreover, the method can be applied to compensate for the performance degradation due to size reduction. Based on the proposed method, as much as a 78...
October 3, 2016: Optics Express
https://www.readbyqxmd.com/read/27819188/feasibility-of-3-d-bioprinting-with-a-modified-desktop-3d-desktop-printer
#15
Todd Goldstein, Lee P Smith, Alex Krush, Kevin Mercadante, Dan Lagalante, Casey Epstein, John A Schwartz, David Zeltsman, Daniel Anthony Grande
Numerous studies have shown the capabilities of 3D printing for use in the medical industry. At the time of this publication, basic home desktop 3-D printer kits can cost as little as $300, while medical-specific 3D bioprinters can cost upwards of $300,000. The purpose of this study was to show how a commercially available desktop 3D printer could be modified to bioprint an engineered poly-L-lactic acid (PLLA) scaffold containing viable chondrocytes in a bioink. Our bioprinter was used to create a living 3D functional tissue-engineered cartilage scaffold...
November 7, 2016: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/27815012/three-dimensional-printed-final-occlusal-splint-for-orthognathic-surgery-design-and-validation
#16
E Shaheen, Y Sun, R Jacobs, C Politis
Orthognathic surgery is indicated for the treatment of significant skeletal malocclusion and is normally prepared using conventional face bows combined with two-dimensional cephalometric analysis and manually made splints. With recent developments in oral imaging, more orthognathic surgeries are being planned using three-dimensional computer-aided design and manufacturing (3D CAD/CAM) software. The purpose of this study was to present a protocol for the design and 3D printing of final digital occlusal splints based on 3D planning of orthognathic surgery and to validate the accuracy of these splints...
November 1, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27813710/usefulness-of-three-dimensional-modeling-in-surgical-planning-resident-training-and-patient-education
#17
Ciro Andolfi, Alejandro Plana, Patrick Kania, P Pat Banerjee, Stephen Small
BACKGROUND: Imaging has a critical impact on surgical decision making and three-dimensional (3D) digital models of patient pathology can now be made commercially. We developed a 3D digital model of a cancer of the head of the pancreas by integrating actual CT data with 3D modeling process. After this process, the virtual pancreatic model was also produced using a high-quality 3D printer. PATIENTS AND METHODS: A 56-year-old female with pancreatic head adenocarcinoma presented with biliary obstruction and jaundice...
November 4, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27806603/a-depth-sensing-technique-on-3d-printed-compensator-for-total-body-irradiation-patient-measurement-and-treatment-planning
#18
Min-Young Lee, Bin Han, Cesare Jenkins, Lei Xing, Tae-Suk Suh
PURPOSE: The purpose of total body irradiation (TBI) techniques is to deliver a uniform radiation dose to the entire volume of a patient's body. Due to variations in the thickness of the patient, it is difficult to produce such a uniform dose distribution throughout the body. In many techniques, a compensator is used to adjust the dose delivered to various sections of the patient. The current study aims to develop and validate an innovative method of using depth-sensing cameras and 3D printing techniques for TBI treatment planning and compensator fabrication...
November 2016: Medical Physics
https://www.readbyqxmd.com/read/27802690/note-3d-printed-spheroid-for-uniform-magnetic-field-generation
#19
Y Öztürk, B Aktaş
This article is focused on a novel and practical production method for a uniform magnetic field generator. The method involves building of a surface coil template using a desktop 3D printer and winding of a conducting wire onto the structure using surface grooves as a guide. Groove pattern was based on the parametric spheroidal helical coil formula. The coil was driven by a current source and the magnetic field inside was measured using a Hall probe placed into the holes on the printed structure. The measurements are found to be in good agreement with our finite element analysis results and indicate a fairly uniform field inside...
October 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27777787/practical-alignment-method-for-x-ray-spectral-measurement-in-micro-ct-system-based-on-3d-printing-technology
#20
Liqiang Ren, Di Wu, Yuhua Li, Bin Zheng, Yong Chen, Kai Yang, Hong Liu
This study presents a practical alignment method for X-ray spectral measurement in a rotating gantry based micro-computed tomography (micro-CT) system using three-dimensional (3D) printing technology. In order to facilitate the spectrometer placement inside the gantry, supporting structures including a cover and a stand were dedicatedly designed and printed using a 3D printer. According to the relative position between the spectrometer and the stand, the upright projection of the spectrometer collimator onto the stand was determined and then marked by a tungsten pinhole...
June 2016: Biomedical Physics & Engineering Express
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