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https://www.readbyqxmd.com/read/29912877/low-cost-three-dimensional-printed-phantom-for-neuraxial-anesthesia-training-development-and-comparison-to-a-commercial-model
#1
Azad Mashari, Mario Montealegre-Gallegos, Jelliffe Jeganathan, Lu Yeh, Joshua Qua Hiansen, Massimiliano Meineri, Feroze Mahmood, Robina Matyal
METHODS: Anonymized CT DICOM data was segmented to create a 3D model of the lumbar spine. The 3D model was modified, placed inside a digitally designed housing unit and fabricated on a desktop 3D printer using polylactic acid (PLA) filament. The model was filled with an echogenic solution of gelatin with psyllium fiber. Twenty-two staff anesthesiologists performed a spinal and epidural on the 3D printed simulator and a commercially available Simulab phantom. Participants evaluated the tactile and ultrasound imaging fidelity of both phantoms via Likert-scale questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29911853/3d-printed-wearable-sensors-with-liquid-metals-for-the-pose-detection-of-snakelike-soft-robots
#2
Luyu Zhou, Qing Gao, Jun-Fu Zhan, Chao-Qi Xie, Jianzhong Fu, Yong He
Liquid metal-based flexible sensors, which utilize advanced liquid conductive material to serve as sensitive element, is emerging as a promising solution to measure large deformations. Nowadays, one of the biggest challenges for precise control of soft robots is the detection of their real time positions. Existing fabrication methods are unable to fabricate flexible sensors that match the shape of soft robots. In this report, we firstly described a novel 3D printed multi-function inductance flexible and stretchable sensor with liquid metals (LMs), which is capable of measuring both axial tension and curvature...
June 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29906220/three-dimensional-printing-of-personalized-nasal-stents-for-patients-with-cleft-lip
#3
Dongyuan Luo, Ting Li, Hongtao Wang, Yiyang Chen
OBJECTIVE: This report describes the design and printing of personalized nasal stents for cleft lip using 3-dimensional (3D) technology. MATERIALS AND METHODS: We used silicone rubber to make the impressions, a 3D laser scanner to obtain 3D data, and Dental SG resin cartridges as printing material. We printed the personalized nasal stents using a photosensitive resin printer. RESULTS: We placed the stents in patients after cleft lip surgery...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29905512/cranioplasty-with-a-low-cost-customized-polymethylmethacrylate-implant-using-a-desktop-3d-printer
#4
Jesús A Morales-Gómez, Everardo Garcia-Estrada, Jorge E Leos-Bortoni, Miriam Delgado-Brito, Luis E Flores-Huerta, Adriana A De La Cruz-Arriaga, Luis J Torres-Díaz, Ángel R Martínez-Ponce de León
OBJECTIVE Cranioplasty implants should be widely available, low in cost, and customized or easy to mold during surgery. Although autologous bone remains the first choice for repair, it cannot always be used due to infection, fragmentation, bone resorption, or other causes, which led to use of synthetic alternatives. The most frequently used allogenic material for cranial reconstructions with long-term results is polymethylmethacrylate (PMMA). Three-dimensional printing technology has allowed the production of increasingly popular customized, prefabricated implants...
June 15, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29903557/3d-volume-rendering-and-3d-printing-additive-manufacturing
#5
REVIEW
Rujuta A Katkar, Robert M Taft, Gerald T Grant
Three-dimensional (3D) volume-rendered images allow 3D insight into the anatomy, facilitating surgical treatment planning and teaching. 3D printing, additive manufacturing, and rapid prototyping techniques are being used with satisfactory accuracy, mostly for diagnosis and surgical planning, followed by direct manufacture of implantable devices. The major limitation is the time and money spent generating 3D objects. Printer type, material, and build thickness are known to influence the accuracy of printed models...
July 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29900562/3d-printed-replicas-for-endodontic-education
#6
M Reymus, C Fotiadou, A Kessler, K Heck, R Hickel, C Diegritz
AIM: To assess the feasibility of producing artificial teeth for endodontic training using 3D printing technology, to analyse the accuracy of the printing process, and to evaluate the teeth by students when used during training. METHODOLOGY: Sound extracted human teeth were selected, digitalized by cone beam computed tomography (CBCT) and appropriate software and finally reproduced by a stereolithographic printer. The printed teeth were scanned and compared with the original ones (trueness) and to one another (precision)...
June 14, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29890772/mineloc-a-rapid-production-of-lab-on-a-chip-biosensors-using-3d-printer-and-the-sandbox-game-minecraft
#7
Kyukwang Kim, Hyeongkeun Kim, Seunggyu Kim, Jessie S Jeon
Here, MineLoC is described as a pipeline developed to generate 3D printable models of master templates for Lab-on-a-Chip (LoC) by using a popular multi-player sandbox game “Minecraft”. The user can draw a simple diagram describing the channels and chambers of the Lab-on-a-Chip devices with pre-registered color codes which indicate the height of the generated structure. MineLoC converts the diagram into large chunks of blocks (equal sized cube units composing every object in the game) in the game world...
June 10, 2018: Sensors
https://www.readbyqxmd.com/read/29883809/additive-manufacturing-of-hierarchical-injectable-scaffolds-for-tissue-engineering
#8
A Béduer, N Piacentini, L Aeberli, A Da Silva, C A Verheyen, F Bonini, A Rochat, A Filippova, L Serex, P Renaud, T Braschler
We present a 3D-printing technology allowing free-form fabrication of centimetre-scale injectable structures for minimally invasive delivery. They result from the combination of 3D printing onto a cryogenic substrate and optimisation of carboxymethylcellulose-based cryogel inks. The resulting highly porous and elastic cryogels are biocompatible, and allow for protection of cell viability during compression for injection. Implanted into the murine subcutaneous space, they are colonized with a loose fibrovascular tissue with minimal signs of inflammation and remain encapsulation-free at three months...
June 5, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29882516/perfusion-directed-3d-mineral-formation-within-cell-laden-hydrogels
#9
Stephen William Sawyer, Shivkumar Vishnempet Shridhar, Kairui Zhang, Lucas Albrecht, Alex Filip, Jason Horton, Pranav Soman
Despite the promise of stem cell engineering and the new advances in bioprinting technologies, one of the major challenges in the manufacturing of large scale bone tissue scaffolds is the inability to perfuse nutrients throughout thick constructs. Here, we report a scalable method to create thick, perfusable bone constructs using a combination of cell-laden hydrogels and a 3D printed sacrificial polymer. Osteoblast-like Saos-2 cells were encapsulated within a gelatin methacrylate (GelMA) hydrogel and 3D printed polyvinyl alcohol (PVA) pipes were used to create perfusable channels...
June 8, 2018: Biofabrication
https://www.readbyqxmd.com/read/29881468/a-new-wipe-sampling-instrument-for-measuring-the-collection-efficiency-of-trace-explosives-residues
#10
Elizabeth L Robinson, Edward Sisco, Matthew E Staymates, Jeffrey A Lawrence
Trace explosives detection, a crucial component of many security screening environments, commonly employs wipe-sampling. Since collection of an explosive residue is necessary for detection, it is important to have a thorough understanding of the parameters that affect the efficiency of collection. Current wipe-sampling evaluation techniques for explosive particles have their limits: manual sampling (with fingers or a wand) is limited in its ability to isolate a single parameter and the TL-slip/peel tester is limited to a linear sample path...
January 14, 2018: Analytical Methods: Advancing Methods and Applications
https://www.readbyqxmd.com/read/29879163/improvement-of-quality-of-3d-printed-objects-by-elimination-of-microscopic-structural-defects-in-fused-deposition-modeling
#11
Evgeniy G Gordeev, Alexey S Galushko, Valentine P Ananikov
Additive manufacturing with fused deposition modeling (FDM) is currently optimized for a wide range of research and commercial applications. The major disadvantage of FDM-created products is their low quality and structural defects (porosity), which impose an obstacle to utilizing them in functional prototyping and direct digital manufacturing of objects intended to contact with gases and liquids. This article describes a simple and efficient approach for assessing the quality of 3D printed objects. Using this approach it was shown that the wall permeability of a printed object depends on its geometric shape and is gradually reduced in a following series: cylinder > cube > pyramid > sphere > cone...
2018: PloS One
https://www.readbyqxmd.com/read/29873765/development-and-implementation-of-an-inexpensive-easily-producible-time-efficient-external-ventricular-drain-simulator-using-3-dimensional-printing-and-image-registration
#12
Hansen Bow, Le He, Muhammad Aanish Raees, Sumit Pruthi, Rohan Chitale
BACKGROUND: External ventricular drain (EVD) placement is one of the most commonly performed procedures in neurosurgery, frequently by the junior neurosurgery resident. Simulators for EVD placement are often costly, time-intensive to create, and complicated to set up. OBJECTIVE: To describe creation of a simulator that is inexpensive, time-efficient, and simple to set up. METHODS: This simulator involves printing a hollow head using a desktop 3-dimensional (3D) printer...
June 5, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29872379/hope-hybrid-drive-combining-optogenetics-pharmacology-and-electrophysiology
#13
Sebastien Delcasso, Sachira Denagamage, Zelie Britton, Ann M Graybiel
Understanding the neural mechanisms underlying human cognition and determining the causal factors for the development of brain pathologies are among the greatest challenges for society. Electrophysiological recordings offer remarkable observations of brain activity as they provide highly precise representations of information coding in both temporal and spatial domains. With the development of genetic tools over the last decades, mice have been a key model organism in neuroscience. However, conducting chronic in vivo electrophysiology in awake, behaving mice remains technically challenging, and this difficulty prevents many research teams from acquiring critical recordings in their mouse models...
2018: Frontiers in Neural Circuits
https://www.readbyqxmd.com/read/29870845/accuracy-and-safety-of-using-customized-guiding-template-for-cervical-pedicle-screw-insertion-in-severe-cervical-deformity-fracture-and-subluxation-a-retrospective-study-of-9-cases
#14
Hsin Hung Wu, I-Chang Su, Cheng-Ta Hsieh, Chih-Ju Chang
PURPOSE: To assess the accuracy and safety of self-developed customized guiding templates used for cervical pedicle screw (CSP) insertion surgery. MATERIALS AND METHODS: A total of 57 screws were implanted in 9 patients with the assistance of the customized guiding templates from July 2016 to December 2017. The customized guiding templates were manufactured from acrylonitrile-butadiene-styrene (ABS) plastic material using a 3D printer after establishing the pedicle screw trajectories for each vertebrae with the assistance of a virtual surgical planning (VSP) software program, developed by our team, for the insertion of CPSs...
June 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29863333/maldi-matrix-application-utilizing-a-modified-3d-printer-for-accessible-high-resolution-mass-spectrometry-imaging
#15
Lulu Tucker, Antonio Conde-González, Diego Cobice, Gregory Hamm, Richard J A Goodwin, Colin J Campbell, David James Clarke, Colin Logan Mackay
Successful matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI) relies on the selection of the most appropriate matrix and optimization of the matrix application parameters. In order to achieve reproducible high spatial-resolution imaging data, several commercially available automated matrix application platforms have become available. How-ever, the high cost of these commercial matrix sprayers is restricting access into this emerging research field. Here, we report an automated platform for matrix deposition, employing a converted commercially-available 3D printer ($300) and other parts commonly found in an analytical chemistry lab as a low-cost alternative to commercial sprayers...
June 4, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29859953/on-site-3-dimensional-printing-and-preoperative-adaptation-decrease-operative-time-for-mandibular-fracture-repair
#16
Brett J King, Earl Peter Park, Brian J Christensen, Raman Danrad
PURPOSE: The purpose of this study was to compare the intraoperative time and operating room costs between patients with mandibular fractures treated with traditional adaptation and fixation and patients treated with preadapted plates created with on-site 3-dimensionally printed models. PATIENTS AND METHODS: We designed a prospective comparative cohort study for patients with mandibular fractures. The control group received traditional open reduction and internal fixation of their mandibular fractures...
May 15, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29849015/the-influence-of-selective-laser-melting-slm-process-parameters-on-in-vitro-cell-response
#17
Bartłomiej Wysocki, Joanna Idaszek, Joanna Zdunek, Krzysztof Rożniatowski, Marcin Pisarek, Akiko Yamamoto, Wojciech Święszkowski
The use of laser 3D printers is very perspective in the fabrication of solid and porous implants made of various polymers, metals, and its alloys. The Selective Laser Melting (SLM) process, in which consolidated powders are fully melted on each layer, gives the possibility of fabrication personalized implants based on the Computer Aid Design (CAD) model. During SLM fabrication on a 3D printer, depending on the system applied, there is a possibility for setting the amount of energy density (J/mm³) transferred to the consolidated powders, thus controlling its porosity, contact angle and roughness...
May 30, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29848804/3d-bioprinter-applied-picosecond-pulsed-electric-fields-for-targeted-manipulation-of-proliferation-and-lineage-specific-gene-expression-in-neural-stem-cells
#18
Ross A Petrella, Pete A Mollica, Martina Zamponi, John A Reid, Shu Xiao, Robert D Bruno, Patrick C Sachs
Picosecond pulse electric fields (psPEF) have the potential to elicit functional changes in mammalian cells in a non-contact manner. Such electro-manipulation of pluripotent and multipotent cells could be a tool in both neural interface and tissue engineering. Here, we describe the potential of psPEF in directing neural stem cells (NSCs) gene expression, metabolism, and proliferation. As a comparison mesenchymal stem cells (MSCs) were also tested.
 Approach. A psPEF electrode was anchored on a customized commercially available 3-D printer, which allowed us to deliver pulses with high spatial precision and systematically control the electrode position in three-axes...
May 31, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29845674/egain-assisted-room-temperature-sintering-of-silver-nanoparticles-for-stretchable-inkjet-printed-thin-film-electronics
#19
Mahmoud Tavakoli, Mohammad H Malakooti, Hugo Paisana, Yunsik Ohm, Daniel Green Marques, Pedro Alhais Lopes, Ana P Piedade, Anibal T de Almeida, Carmel Majidi
Coating inkjet-printed traces of silver nanoparticle (AgNP) ink with a thin layer of eutectic gallium indium (EGaIn) increases the electrical conductivity by six-orders of magnitude and significantly improves tolerance to tensile strain. This enhancement is achieved through a room-temperature "sintering" process in which the liquid-phase EGaIn alloy binds the AgNP particles (≈100 nm diameter) to form a continuous conductive trace. Ultrathin and hydrographically transferrable electronics are produced by printing traces with a composition of AgNP-Ga-In on a 5 µm-thick temporary tattoo paper...
May 29, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29813103/open-source-micro-tensile-testers-via-additive-manufacturing-for-the-mechanical-characterization-of-thin-films-and-papers
#20
Krishanu Nandy, David W Collinson, Charlie M Scheftic, L Catherine Brinson
The cost of specialized scientific equipment can be high and with limited funding resources, researchers and students are often unable to access or purchase the ideal equipment for their projects. In the fields of materials science and mechanical engineering, fundamental equipment such as tensile testing devices can cost tens to hundreds of thousands of dollars. While a research lab often has access to a large-scale testing machine suitable for conventional samples, loading devices for meso- and micro-scale samples for in-situ testing with the myriad of microscopy tools are often hard to source and cost prohibitive...
2018: PloS One
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