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Pelvic organ prolapse

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https://www.readbyqxmd.com/read/28822841/the-effciency-and-safety-of-tvt-abbrevo-versus-tvt-exact-in-the-normal-weight-and-overweight-patients-affected-by-stress-urinary-incontinence
#1
Yi Sun, Deyi Luo, Lu Yang, Xin Wei, Cai Tang, Mei Chen, Hong Shen, Qiang Wei
OBJECTIVE: To compare the compare efficacy between the two differernt slings in normal weight and overweight women. METHODS: There were 426 women, 220 women (119 normal weight and 101 overweight) accepted the TVT-A and 206 womens (141 normal weight and 92 overweight) accepted the TVT-E procedure. Data collected contained the subjectively efficiency, objectively efficiency, Questionnaire-Short Form (ICIQ-SF), Incontinence Quality Of Life questionnaire (I-QOL), Pelvic Floor Impact Questionnaire short form (PFIQ-7), Urogenital Distress Inventory short form (UDI-6) and (Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire short form) PISQ-12 at the 36 months after the surgery...
August 16, 2017: Urology
https://www.readbyqxmd.com/read/28815283/risk-factors-for-recurrence-after-hysterectomy-plus-native-tissue-repair-as-primary-treatment-for-genital-prolapse
#2
Stefano Manodoro, Matteo Frigerio, Alice Cola, Federico Spelzini, Rodolfo Milani
INTRODUCTION AND HYPOTHESIS: Identification of risk factors for pelvic organ prolapse (POP) recurrence is crucial to provide adequate preoperative counselling and tailor surgical treatment. The aim of this retrospective study was to identify risk factors for recurrence in a large series of patients with POP treated with primary transvaginal native-tissue repair involving high uterosacral ligament suspension. METHODS: Postoperative descent of POP-Q stage 2 or higher in any compartment was considered as recurrence...
August 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28815277/discontinuation-rate-and-adverse-events-after-1%C3%A2-year-of-vaginal-pessary-use-in-women-with-pelvic-organ-prolapse
#3
Theerarat Yimphong, Teerayut Temtanakitpaisan, Pranom Buppasiri, Chompilas Chongsomchai, Supparaluck Kanchaiyaphum
INTRODUCTION AND HYPOTHESIS: To ascertain the rate of discontinuation after vaginal pessary use among pelvic organ prolapse patients. METHODS: We enrolled women suffering from pelvic organ prolapse who opted to use vaginal pessary as the first line of treatment and were fitted with a pessary at the urogynecological clinic in Khon Kaen University's Srinagarind Hospital (Thailand) during the period between 2010 and 2016. Patients' medical records were retrospectively reviewed...
August 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28803112/in-vivo-documentation-of-shape-and-position-changes-of-mri-visible-mesh-placed-in-rectovaginal-septum
#4
Urbankova Iva, Sindhwani Nikhil, Callewaert Geertje, Turri Alice, Rinkijevic Rita, Hympanova Lucie, Feola Andrew, Deprest Jan
BACKGROUND AND OBJECTIVE: Large deformations in synthetic meshes used in pelvic organ prolapse surgery may lead to suboptimal support for the underlying tissue, graft-related complications as well as recurrence. Our aim was to quantify in vivo longitudinal changes in mesh shape and geometry in a large animal model. We compare two commonly used mesh shapes, armed and flat, that are differently affixed. The secondary outcomes were active and passive biomechanical properties. METHODS: A total of 18 animals were used...
August 5, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28802943/pregnancy-outcomes-after-transvaginal-sacrospinous-hysteropexy
#5
Sabri Cavkaytar, Mahmut Kuntay Kokanalı, Umit Tasdemir, Melike Doganay, Orhan Aksakal
AIM: To evaluate the pregnancy outcomes in women who underwent transvaginal sacrospinous hysteropexy with the review of the literature STUDY DESIGN: 54 women who underwent transvaginal sacrospinous hysteropexy due to ≥grade 2 uterine prolapse during six-year period were identified from a computer based database. 8 of these who had pregnancy resulted in live birth subsequent to transvaginal sacrospinous hysteropexy were enrolled in this study. They were examined in case of pelvic organ prolapse recurrence and were questioned about their current self satisfaction status and PISQ-12 questionnaire...
August 4, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28799675/biomimetic-implants-for-pelvic-floor-repair
#6
REVIEW
Mahshid Vashaghian, Sebastianus J Zaat, Theodoor H Smit, Jan-Paul Roovers
BACKGROUND: Polypropylene implants are used for the reconstructive surgery of urogynaecological disorders like pelvic organ prolapse, but severe complications associated with their use have been reported. There is evidence that surface properties and a difference in mechanical stiffness between the implant and the host tissue contribute to these adverse events. Electrospinning is an innovative engineering alternative that provides a biomimetic microstructure for implants, resulting in a different mechano-biological performance...
August 11, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28794464/expression-changes-in-pelvic-organ-prolapse-a-systematic-review-and-in-silico-study
#7
Maryam B Khadzhieva, Dmitry S Kolobkov, Svetlana V Kamoeva, Lyubov E Salnikova
Pelvic organ prolapse (POP) is a highly disabling condition common for a vast number of women worldwide. To contribute to existing knowledge in POP pathogenesis, we performed a systematic review of expression studies on both specific gene and whole-genome/proteome levels and an in silico analysis of publicly available datasets related to POP development. The most extensively investigated genes in individual studies were related to extracellular matrix (ECM) organization. Three premenopausal and two postmenopausal sets from two Gene Expression Omnibus (GEO) studies (GSE53868 and GSE12852) were analyzed; Gene Ontology (GO) terms related to tissue repair (locomotion, biological adhesion, immune processes and other) were enriched in all five datasets...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28783735/the-role-of-gpx1-in-the-pathogenesis-of-female-pelvic-organ-prolapse
#8
Shasha Hong, Li Hong, Bingshu Li, Debin Wu, Cheng Liu, Jie Min, Wenjun Guo, Ming Hu, Jianming Tang, Yang Li
Gestation and delivery can increase intra-abdominal pressure, which are well-known risk factors for Pelvic Organ Prolapse (POP). But the pathogenesis mechanism of POP remains unclear. Our previous research showed that the expression of glutathione peroxidase type 1 (GPX1) decreased in pelvic floor ligaments from POP patients, implying that oxidative stress (OS) may be related to POP. The aim of this study was to figure out the role of GPx1 regulation in the pathogenesis of POP. Women (>45 years) who received hysterectomy surgery were enrolled in this research, identified by screening...
2017: PloS One
https://www.readbyqxmd.com/read/28777192/sexual-function-after-prolapse-repair
#9
Abigail Shatkin-Margolis, Rachel N Pauls
PURPOSE OF REVIEW: The purpose of this review is to summarize available literature (from the last 18 months) assessing sexual function following pelvic reconstructive surgery for pelvic organ prolapse (POP). We include vaginal native tissue repair, abdominal/laparoscopic sacrocolpopexy, transvaginal mesh repair, and obliterative procedures. The goal is to assist providers in counseling patients and to identify areas needed for further research. RECENT FINDINGS: When compared with pessary management, women who undergo POP surgical repair achieve their sexual function goals more often...
August 1, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28770896/six-arms-mesh-implant-application-with-organ-preserving-in-a-young-patient-with-total-pelvic-organ-prolapse
#10
Gokmen Sukgen, Adem Altunkol, Deniz Abat
Pelvic Organ Prolapse (POP) is defined as the prolapse of the pelvic organs toward or through the vaginal opening as a result of the weakening of the combination of nerves, muscles and fascia, which normally protect and support the physical position of pelvic organs. In this case report, the 30-year old patient who applied with the pelvic prolapse through the vaginal opening was treated with Sacro Uterine Ligamentopexy and anterior 6 arms mesh implant, without applying hysterectomy. In the short follow-up period of three months, both anatomic improvement and positive developments in sexual and social life have been recorded in the patient's life...
July 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28767163/predictors-of-sexual-function-in-women-with-stress-urinary-incontinence
#11
Magdalena E Grzybowska, Dariusz Wydra
AIMS: To assess female sexual function (SF) in different grades of urodynamic stress urinary incontinence (SUI), with/without pelvic organ prolapse (POP); to investigate associations between clinical data and pelvic organ prolapse/urinary incontinence sexual questionnaire (PISQ) scores. METHODS: A cross-sectional study was conducted in sexually active women (130 with SUI and 126 controls). Stamey score and POP quantification (POP-Q) were used. Urogynecological examinations were performed; all participants completed PISQ...
August 2, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28762699/pelvic-organ-prolapse
#12
(no author information available yet)
No abstract text is available yet for this article.
August 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28762694/pelvic-organ-prolapse
#13
REVIEW
Cheryl B Iglesia, Katelyn R Smithling
Pelvic organ prolapse is the descent of one or more of the anterior vaginal wall, posterior vaginal wall, the uterus (cervix), or the apex of the vagina (vaginal vault or cuff scar after hysterectomy). Prevalence increases with age. The cause of prolapse is multifactorial but is primarily associated with pregnancy and vaginal delivery, which lead to direct pelvic floor muscle and connective tissue injury. Hysterectomy, pelvic surgery, and conditions associated with sustained episodes of increased intra-abdominal pressure, including obesity, chronic cough, constipation, and repeated heavy lifting, also contribute to prolapse...
August 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28762621/repair-of-damaged-ligaments-with-tissue-fixation-system-minisling-is-sufficient-to-cure-major-prolapse-in-all-three-compartments-5-year-data
#14
Hiromi Inoue, Yutaka Kohata, Takanori Fukuda, Mika Monma, Yosie Uzawa, Yuina Kubo, Remi Watanabe, Takeshi Kusaka
AIM: The ageing population in Japan brings problems of pelvic organ prolapse (POP), bladder and bowel incontinence, and fragility as regards major pelvic surgery. Existing data from tissue fixation system (TFS) surgery show high cure rates for these conditions, but long-term data are lacking. We aimed to elucidate the usefulness of TFS by assessing 5-year postoperative outcomes. METHODS: A total of 68 patients, mean age 70 years, underwent total pelvic floor repair...
August 1, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28746921/effects-of-transobturator-midurethral-sling-surgery-on-sexual-functions-one-year-follow-up
#15
Ergul Aslan, Funda Gungor Ugurlucan, Dilek Bilgic, Onay Yalcin, Nezihe Kizilkaya Beji
AIM: To evaluate sexual functions of women having stress urinary incontinence (SUI) preoperatively and 6 months and 12 months after undergoing a transobturator tape (TOT) ± pelvic organ prolapse (POP) surgery. METHODS: One hundred-ninety-five women with SUI ± POP were recruited and 150 sexually active women who had clinical ± urodynamic SUI and underwent TOT ± POP surgery were included in this prospective study. Urogynecologic symptoms were evaluated preoperatively, at 6 months, and 12 months by Female Sexual Function Index (FSFI)...
July 27, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28741303/open-retropubic-colposuspension-for-urinary-incontinence-in-women
#16
REVIEW
Marie Carmela M Lapitan, June D Cody, Atefeh Mashayekhi
BACKGROUND: Urinary incontinence is a common and potentially debilitating problem. Stress urinary, incontinence as the most common type of incontinence, imposes significant health and economic burdens on society and the women affected. Open retropubic colposuspension is a surgical treatment which involves lifting the tissues near the bladder neck and proximal urethra in the area behind the anterior pubic bones to correct deficient urethral closure to correct stress urinary incontinence...
July 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28733916/hysterectomy-technique-and-risk-of-pelvic-organ-prolapse-repair-a-danish-nationwide-cohort-study
#17
Rune Lykke, Ea Løwenstein, Jan Blaakær, Helga Gimbel
PURPOSE: The purpose was to investigate, in a large cohort, how hysterectomy technique influences the incidence of subsequent pelvic organ prolapse (POP) repair among women hysterectomized for benign conditions. METHODS: From the Danish National Patient Registry, we collected data on all hysterectomies on benign indications, and all POP operations performed in Denmark from January 1, 1977 to June 10, 2016. We excluded patients with prior POP repair. We analyzed the incidence of POP surgery by cumulative incidence curves and hazard ratio (HR) for women with and without POP diagnoses or concomitant POP repair at hysterectomy...
July 21, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28733790/is-a-dragging-sensation-a-symptom-of-female-pelvic-organ-prolapse
#18
Hans Peter Dietz, Candice Chatel, Ixora Kamisan Atan
INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) commonly presents with a "vaginal lump or bulge" and/or a "dragging sensation." The first symptom correlates strongly with clinical and imaging data. However, a "dragging sensation" may be less specific. Hence, we investigated the predictive value of both symptoms for POP. METHODS: This was a retrospective study involving archived data sets of women seen between November 2013 and May 2014. All underwent a clinical interview, POPQ examination, and 4D translabial ultrasound (TLUS)...
July 21, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28733058/unusual-perils-of-pelvic-organ-prolapse
#19
Brian J Liu, Patricia E Lee
BACKGROUND: Prolapse can be treated with expectant management, pessary, or surgery. Although we consider the first two options benign, rare but serious complications can arise. CASE 1: A 64-year-old presented with recurrent grade 4 prolapse. After 6 months of expectant management, she developed a fistula from an ulcerated area of the prolapse into the peritoneal cavity. CASE 2: An 81-year-old who diligently cared for her ring pessary for 18 years presented with a vesicovaginal fistula...
July 18, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28730531/comparing-different-tissue-engineered-repair-materials-for-the-treatment-of-pelvic-organ-prolapse-and-urinary-incontinence-which-material-is-better
#20
Xiaojuan Wang, Yisong Chen, Zhongyong Fan, Keqin Hua
INTRODUCTION AND HYPOTHESIS: Synthetic non-absorbable meshes are widely used to augment surgical repair of pelvic organ prolapse (POP) and stress urinary incontinence (SUI), but these meshes are associated with serious complications. This study compares the attachment and extracellular matrix (ECM) production of adipose-derived stem cells (ADSCs) on different biodegradable nanomaterials to develop tissue engineered repair materials. METHODS: Rat ADSCs were isolated and cultured on electrospun poly-L-lactic acid (PLA) and electrospun poly(L-lactide)-trimethylene carbonate-gycolide (PLTG) terpolymers for 1 and 2 weeks...
July 20, 2017: International Urogynecology Journal
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