keyword
MENU ▼
Read by QxMD icon Read
search

Locked in

keyword
https://www.readbyqxmd.com/read/28214576/amplified-induced-neural-oscillatory-activity-predicts-musicians-benefits-in-categorical-speech-perception
#1
Gavin M Bidelman
Event-related brain potentials (ERPs) reveal musical experience refines neural encoding and confers stronger categorical perception (CP) and neural organization for speech sounds. In addition to evoked brain activity, the human EEG can be decomposed into induced (non-phase-locked) response whose various frequency bands reflect different mechanisms of perceptual-cognitive processing. Here, we aimed to clarify which spectral properties of these neural oscillations are most prone to music-related neuroplasticity and which are linked to behavioral benefits in the categorization of speech...
February 15, 2017: Neuroscience
https://www.readbyqxmd.com/read/28214499/current-techniques-to-treat-pathologic-perforator-veins
#2
Kathleen Ozsvath, Eric Hager, Michael Harlander-Locke, Elna Masuda, Steve Elias, Ellen D Dillavou
Pathologic perforating veins have become an interest to the venous specialist caring for patients with CEAP 4 to 6 disease. Historically, open perforator ligation and then subdermal endoscopic perforator ligation was described. These methods had clear shortcomings. More recently, thermal ablation techniques, including radiofrequency ablation and laser ablation, have been described. Ultrasound-guided sclerotherapy has also been used as a possible means to treat pathologic perforator veins. This report describes and summarizes the updated techniques to treat perforating veins in a challenging patient population...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28214457/operative-fixation-of-rib-fractures-indications-techniques-and-outcomes
#3
David Galos, Benjamin Taylor, Toni McLaurin
Rib fractures are extremely common injuries and vary in there severity from single nondisplaced fractures to multiple segmental fractures resulting in flail chest and respiratory compromise. Historically, rib fractures have been treated conservatively with pain control and respiratory therapy. However this method may not be the best treatment modality in all situations. Operative fixation of select rib fractures has been increasing in popularity especially in patients with flail chest and respiratory compromise...
January 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28214455/dorsal-plating-of-distal-radius-fractures-historical-context-and-appropriate-use
#4
Omri Ayalon, Nader Paksima
The management of distal radius fractures has evolved over time from a largely nonoperative paradigm to a more commonly performed operative procedures today. Surgical trends have similarly developed, with dorsal plating falling out of favor due to complications involving extensor tendon pathology as well as due to the ubiquity of the volar plate along with the advent of locking plate technology. However, with the improvement in design of newer generation dorsal plates, this technique should be used in the appropriate clinical situation, including dorsal comminution and angulation with concomitant carpal pathology...
January 2017: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/28212557/using-high-sensitivity-sequencing-for-the-detection-of-mutations-in-btk-and-plc%C3%AE-2-genes-in-cellular-and-cell-free-dna-and-correlation-with-progression-in-patients-treated-with-btk-inhibitors
#5
Adam Albitar, Wanlong Ma, Ivan DeDios, Jeffrey Estella, Inhye Ahn, Mohammed Farooqui, Adrian Wiestner, Maher Albitar
Patients with chronic lymphocytic leukemia (CLL) that develop resistance to Bruton tyrosine kinase (BTK) inhibitors are typically positive for mutations in BTK or phospholipase c gamma 2 (PLCγ2). We developed a high sensitivity (HS) assay utilizing wild-type blocking polymerase chain reaction achieved via bridged and locked nucleic acids. We used this high sensitivity assay in combination with Sanger sequencing and next generation sequencing (NGS) and tested cellular DNA and cell-free DNA (cfDNA) from patients with CLL treated with the BTK inhibitor, ibrutinib...
February 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/28211816/levodopa-carbidopa-intestinal-gel-pharmacokinetics-lower-variability-than-oral-levodopa-carbidopa
#6
Ahmed A Othman, Matthew Rosebraugh, Krai Chatamra, Charles Locke, Sandeep Dutta
In a double-blind, double-dummy, double-titration Phase 3 trial in advanced Parkinson's disease (PD) patients, the efficacy and safety of Levodopa-carbidopa intestinal gel (LCIG) infusion were characterized relative to immediate-release oral levodopa-carbidopa (LC-oral) treatment. We present in this report the comparative pharmacokinetic profiles of LCIG and LC-oral from this pivotal study. The results presented in this report clearly demonstrate that LCIG results in lower variability and fluctuations in levodopa and carbidopa plasma concentrations compared to LC-oral...
February 16, 2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28211451/motor-neuron-disease-communication-for-completely-locked-in-patients
#7
Ian Fyfe
No abstract text is available yet for this article.
February 17, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28211205/locking-interconversion-of-aromatic-oligoamide-foldamers-by-intramolecular-side-chain-crosslinking-toward-absolute-control-of-helicity-in-synthetic-aromatic-foldamers
#8
Lu Zheng, Chengyuan Yu, Yulin Zhan, Xuebing Deng, Ying Wang, Hua Jiang
A series of foldamers of 8-amino-2-quinolinecarboxylic acid were stapled by intramolecular ring-closing olefin metathesis to generate the constrained aromatic foldamers with varying lengths of hydrocarbon side-chains. Investigations clearly revealed that the side-chain crosslinkers are capable of completely locking the interconversions of the stapled aromatic foldamers over a wide range of temperature in CDCl3, even in C2D2Cl4. Hence, the stapled foldamers with the short hydrocarbon crosslinker can be easily separated by silica gel chromatography to generate foldamers with stable, absolute one-handed helicity...
February 16, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28210709/clinical-outcomes-of-eus-guided-drainage-of-debris-containing-pancreatic-pseudocysts-a-large-multicenter-study
#9
Dennis Yang, Sunil Amin, Susana Gonzalez, Daniel Mullady, Steven A Edmundowicz, John M DeWitt, Mouen A Khashab, Andrew Y Wang, Satish Nagula, Jonathan M Buscaglia, Juan Carlos Bucobo, Mihir S Wagh, Peter V Draganov, Tyler Stevens, John J Vargo, Harshit S Khara, David L Diehl, Rajesh N Keswani, Srinadh Komanduri, Patrick S Yachimski, Anoop Prabhu, Richard S Kwon, Rabindra R Watson, Adam J Goodman, Petros Benias, David L Carr-Locke, Christopher J DiMaio
Background and study aims Data on clinical outcomes of endoscopic drainage of debris-free pseudocysts (PDF) versus pseudocysts containing solid debris (PSD) are very limited. The aims of this study were to compare treatment outcomes between patients with PDF vs. PSD undergoing endoscopic ultrasound (EUS)-guided drainage via transmural stents. Patients and methods Retrospective review of 142 consecutive patients with pseudocysts who underwent EUS-guided transmural drainage (TM) from 2008 to 2014 at 15 academic centers in the United States...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28210529/awareness-of-gestational-diabetes-and-its-risk-factors-among-pregnant-women-in-samoa
#10
Lucy Anne Price, Lauren Jade Lock, Lucy Elizabeth Archer, Zubair Ahmed
Gestational diabetes mellitus (GDM) is a subtype of diabetes mellitus defined as the development, or first recognition, of glucose intolerance during pregnancy. The risk of developing type 2 diabetes mellitus (T2DM) is greater in mothers with GDM compared to the general population. Preventing the development of GDM could help lower the prevalence of T2DM and long-term morbidity in children of affected mothers. The purpose of this study was to investigate the awareness of GDM and its risk factors among pregnant women in Samoa, exploring where participants obtained information, and understanding their attitudes towards diet and physical activity...
February 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28210218/phasic-firing-and-coincidence-detection-by-subthreshold-negative-feedback-divisive-or-subtractive-or-better-both
#11
Gemma Huguet, Xiangying Meng, John Rinzel
Phasic neurons typically fire only for a fast-rising input, say at the onset of a step current, but not for steady or slow inputs, a property associated with type III excitability. Phasic neurons can show extraordinary temporal precision for phase locking and coincidence detection. Exemplars are found in the auditory brain stem where precise timing is used in sound localization. Phasicness at the cellular level arises from a dynamic, voltage-gated, negative feedback that can be recruited subthreshold, preventing the neuron from reaching spike threshold if the voltage does not rise fast enough...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28210214/arginine-vasopressin-alters-both-spontaneous-and-phase-locked-synaptic-inputs-to-airway-vagal-preganglionic-neuron-via-activation-of-v1a-receptor-insights-into-stress-related-airway-vagal-excitation
#12
Xianxia Yan, Xingxin Chen, Yuhong Guo, Ding He, Yonghua Chen, Chunmei Xia, Jijiang Wang
The airway vagal preganglionic neurons (AVPNs) in the external formation of the nucleus ambiguus (eNA) play a major role in the vagal control of tracheobronchial smooth muscle tone and maintenance of airway resistance. The eNA receives vasopressinergic projection from the hypothalamic paraventricular nucleus (PVN), the key node for the genesis of psychological stress. Since airway vagal excitation is reportedly to be associated with the psychological stress-induced/exacerbated airway hyperresponsiveness in asthmatics, arginine vasopressin (AVP) might be involved in stress-related airway vagal excitation...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28210048/effect-of-a-pelvic-wedge-and-belt-on-the-medial-and-lateral-hamstring-muscles-during-knee-flexion
#13
Won-Gyu Yoo
[Purpose] This study developed a pelvic wedge and belt and investigated their effects on the selective activation of medial and lateral hamstring muscles during knee flexion. [Subjects and Methods] Nine adults were enrolled. The participants performed exercises without and with the pelvic wedge and belt, and the electromyographic activities of the medial and lateral hamstring muscles were recorded. [Results] The activity of the medial hamstring was increased significantly when using the pelvic wedge and belt, while the activity of the lateral hamstring did not differ significantly...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28208957/open-reduction-and-internal-fixation-of-displaced-calcaneum-intra-articular-fractures-by-locking-calcaneal-plate
#14
Santosha, Shams Gulrez, Arambam Mahendra Singh, Sanjib Waikhom, Vishal Pakhrin, Sagnik Mukherjee, Rajkumar Debbarma, Prabhu Shrinivas Prashant
INTRODUCTION: Calcaneal fractures constitute the most common fractures in hindfoot. Lots of controversies exist in the management of calcaneal fractures but now-a-days, it is preferable to perform open reduction and internal fixation and early mobilizatation. AIM: To evaluate the functional outcome after open reduction and internal fixation of displaced intra-articular fractures of the calcaneum by locking calcaneal plate. MATERIALS AND METHODS: The study was conducted in the Department of Orthopaedic Surgery from September 2013 to April 2016...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208953/open-reduction-and-volar-plate-fixation-of-dorsally-displaced-distal-radius-fractures-a-prospective-study-of-functional-and-radiological-outcomes
#15
Arjun Ballal, Anand Kumar Sadasivan, Anoop Hegde, Ashwin Shetty
INTRODUCTION: The fractures of the distal radius have always posed a unique challenge to the orthopaedic fraternity. The complex ligamentous and bony anatomy offers a wide variety of fractures to be dealt with around this zone. Over the years these injuries have become common especially in the elderly age group as well as the implants and surgical techniques have improved. AIM: To assess the radiological and functional outcome after fixation of intra-articular dorsally displaced distal radius fractures with open reduction and volar Locking Compression Plate fixation (LCP)...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208474/key-lock-colloids-in-a-nematic-liquid-crystal
#16
Nuno M Silvestre, M Tasinkevych
The Landau-de Gennes free energy is used to study theoretically the effective interaction of spherical "key" and anisotropic "lock" colloidal particles. We assume identical anchoring properties of the surfaces of the key and of the lock particles, and we consider planar degenerate and perpendicular anchoring conditions separately. The lock particle is modeled as a spherical particle with a spherical dimple. When such a particle is introduced into a nematic liquid crystal, it orients its dimple at an oblique angle θ_{eq} with respect to the far field director n_{∞}...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28208342/phase-reduction-theory-for-hybrid-nonlinear-oscillators
#17
Sho Shirasaka, Wataru Kurebayashi, Hiroya Nakao
Hybrid dynamical systems characterized by discrete switching of smooth dynamics have been used to model various rhythmic phenomena. However, the phase reduction theory, a fundamental framework for analyzing the synchronization of limit-cycle oscillations in rhythmic systems, has mostly been restricted to smooth dynamical systems. Here we develop a general phase reduction theory for weakly perturbed limit cycles in hybrid dynamical systems that facilitates analysis, control, and optimization of nonlinear oscillators whose smooth models are unavailable or intractable...
January 2017: Physical Review. E
https://www.readbyqxmd.com/read/28207779/self-organized-synchronization-of-digital-phase-locked-loops-with-delayed-coupling-in-theory-and-experiment
#18
Lucas Wetzel, David J Jörg, Alexandros Pollakis, Wolfgang Rave, Gerhard Fettweis, Frank Jülicher
Self-organized synchronization occurs in a variety of natural and technical systems but has so far only attracted limited attention as an engineering principle. In distributed electronic systems, such as antenna arrays and multi-core processors, a common time reference is key to coordinate signal transmission and processing. Here we show how the self-organized synchronization of mutually coupled digital phase-locked loops (DPLLs) can provide robust clocking in large-scale systems. We develop a nonlinear phase description of individual and coupled DPLLs that takes into account filter impulse responses and delayed signal transmission...
2017: PloS One
https://www.readbyqxmd.com/read/28207333/handgun-legislation-and-changes-in-statewide-overall-suicide-rates
#19
Michael D Anestis, Joye C Anestis, Sarah E Butterworth
OBJECTIVES: To examine the extent to which 4 laws regulating handgun ownership were associated with statewide suicide rate changes. METHODS: To test between-group differences in statewide suicide rate changes between 2013 and 2014 in all 50 states and the District of Columbia with and without specific laws, we ran analyses of covariance. RESULTS: We found significant differences in suicide rate changes from 2013 to 2014 in states with mandatory waiting periods and universal background checks relative to states without such laws...
February 16, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28205485/asymptomatic-flexor-tendon-damages-after-volar-locking-plate-fixation-of-distal-radius-fractures
#20
Susumu Tokunaga, Yoshihiro Abe
BACKGROUND: To investigate asymptomatic flexor tendon damages after volar locking plate fixation of distal radius fractures in 32 wrists of 32 patients with distal radius fractures fixed using two plate types. Sixteen patients received the Acu-Loc volar distal radius plate, and the remaining 16 patients received the Aptus distal radius correction plate. METHODS: The flexor pollicis longus (FPL) tendon and flexor digitorum profundus were evaluated according to intraoperative findings at plate removal...
March 2017: Journal of Hand Surgery Asian-Pacific Volume
keyword
keyword
84759
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"