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https://www.readbyqxmd.com/read/29217142/pharmacist-led-depression-screening-and-intervention-in-an-underserved-rural-and-multiethnic-diabetic-population
#1
Charlotte Wilson, Geoffrey Twigg
OBJECTIVES: To test the feasibility of implementation and integration of community pharmacist-led depression screening for patients with diabetes in an underserved rural area and to assess the response rate of prescribers to pharmacist-led depression screening and treatment recommendation. SETTING: Independent community pharmacy-run diabetes education center. PRACTICE DESCRIPTION: Clinical community pharmacy site on Maryland's Eastern Shore...
December 4, 2017: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/29212532/delivery-of-screening-and-brief-intervention-for-unhealthy-alcohol-use-in-an-urban-academic-federally-qualified-health-center
#2
Marcus A Bachhuber, Megan A O'Grady, Henry Chung, Charles J Neighbors, Joseph DeLuca, Elenita M D'Aloia, Arelis Diaz, Chinazo O Cunningham
BACKGROUND: Screening and brief intervention (SBI) for unhealthy drinking has not been widely implemented in primary care partly due to reliance on physicians to perform it. METHODS: We implemented a model of nursing staff-delivered SBI for unhealthy drinking for adult patients receiving primary care at an academically-affiliated Federally Qualified Health Center in the Bronx, NY. Our model consisted of nursing staff screening all patients with the alcohol use disorders identification test consumption questions (AUDIT-C) and, if screening positive, providing BI or referral to specialty services...
December 7, 2017: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29207795/association-between-vascular-endothelial-markers-and-carotid-intima-media-thickness-in-children-and-adolescents-with-type-1-diabetes-mellitus
#3
Noushin Rostampour, Kiavash Fekri, Elham Hashemi-Dehkordi, Mahdieh Obodiat
Introduction: Type 1 Diabetes Mellitus (T1DM) is one of the important risk factor for cardiovascular disease. Endothelial dysfunction and increased Carotid Intima-Media Thickness (CIMT) result in cardiovascular complications. Vascular Cell Adhesion Molecule-1 (VCAM-1) and Intercellular Adhesion Molecule-1 (ICAM-1) are two adhesion molecules that are markers of early atherosclerosis and play a significant role in developing atherosclerosis. Aim: To evaluate CIMT and its association with the levels of ICAM-1 and VCAM-1 in children and adolescents with T1DM...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29204366/assessment-of-diabetic-polyneuropathy-in-zanzibar-comparison-between-traditional-methods-and-an-automated-point-of-care-nerve-conduction-device
#4
Elinor C Vogt, Marianne Øksnes, Faiza Suleiman, Buthayna Ali Juma, Hrafnkell B Thordarson, Ola Ommedal, Eirik Søfteland
Aim: Scant information is available about the prevalence of diabetic polyneuropathy, as well as the applicability of screening tools in sub-Saharan Africa. We aimed to investigate these issues in Zanzibar (Tanzania). Methods: One hundred consecutive diabetes patients were included from the diabetes clinic at Mnazi Mmoja Hospital. Clinical characteristics were recorded. Further, we investigated: a) self-reported numbness of the lower limbs, b) ten-point monofilament test, c) the Sibbald 60-s Tool and d) nerve conduction studies (NCS, using an automated handheld point-of-care device, the NC-stat DPNCheck)...
December 2017: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/29202988/mobile-phone-generated-vibrations-used-to-detect-diabetic-peripheral-neuropathy
#5
Jonathan David May, Matthew William John Morris
BACKGROUND: In the current United Kingdom population the incidence of diabetic peripheral neuropathy is increasing. The presence of diabetic neuropathy affects decision making and treatment options. This study seeks to evaluate if the vibrations generated from a mobile phone can be used to screen patients for diabetic peripheral neuropathy. METHODS: This study comprised of 61 patients; a control group of 21 patients; a lower limb injury group of 19 patients; a diabetic peripheral neuropathy group of 21 patients...
December 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29201921/selective-screening-strategies-for-gestational-diabetes-a-prospective-cohort-observational-study
#6
Sumaiya Adam, Paul Rheeder
Aim: We aimed to develop a prediction model for the diagnosis of gestational diabetes and to evaluate the performance of published prediction tools on our population. Methods: We conducted a cohort study on nondiabetic women < 26 weeks gestation at a level 1 clinic in Johannesburg, South Africa. At recruitment, participants completed a questionnaire and random basal glucose and HbA1c were evaluated. A 75 g 2-hour OGTT was scheduled between 24-28 weeks gestation, as per FIGO guidelines...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29201075/development-and-evaluation-of-patient-information-leaflet-for-diabetic-foot-ulcer-patients
#7
Sonal Sekhar M, Unnikrishnan Mk, Navya Vyas, Gabriel Sunil Rodrigues
Background: Patient education (PE) is as important as medical and surgical interventions in the management of diabetic foot ulcer (DFU). Patient information leaflets (PILs) are globally accepted patient counseling aids. Objectives: This study aimed at developing PILs for DFU patients and investigating its validation. Methods: The PILs were prepared based on different model leaflets available from various online resources, including "Patient UK"...
July 2017: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29196298/risk-assessment-in-patients-with-diabetes-with-the-timi-risk-score-for-atherothrombotic-disease
#8
Brian A Bergmark, Deepak L Bhatt, Eugene Braunwald, David A Morrow, Ph Gabriel Steg, Yared Gurmu, Avivit Cahn, Ofri Mosenzon, Itamar Raz, Erin Bohula, Benjamin M Scirica
OBJECTIVE: Improved risk assessment for patients with type 2 diabetes and elevated cardiovascular (CV) risk is needed. The TIMI Risk Score for Secondary Prevention (TRS 2°P) predicts a gradient of risk in patients with prior myocardial infarction (MI) but has not been evaluated in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: CV event rates were compared by baseline TRS 2°P in 16,488 patients enrolled in SAVOR-TIMI 53 with type 2 diabetes and high CV risk or established CV disease...
December 1, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29191260/physical-activity-as-a-vital-sign-a-systematic-review
#9
Yvonne M Golightly, Kelli D Allen, Kirsten R Ambrose, Jamie L Stiller, Kelly R Evenson, Christiane Voisin, Jennifer M Hootman, Leigh F Callahan
INTRODUCTION: Physical activity (PA) is strongly endorsed for managing chronic conditions, and a vital sign tool (indicator of general physical condition) could alert providers of inadequate PA to prompt counseling or referral. This systematic review examined the use, definitions, psychometric properties, and outcomes of brief PA instruments as vital sign measures, with attention primarily to studies focused on arthritis. METHODS: Electronic databases were searched for English-language literature from 1985 through 2016 using the terms PA, exercise, vital sign, exercise referral scheme, and exercise counseling...
November 30, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/29191108/a-screening-tool-using-five-risk-factors-was-developed-for-fall-risk-prediction-in-chinese-community-dwelling-elderly-individuals
#10
Li Kang, Xiaoyu Chen, Peipei Han, Yixuan Ma, Liye Jia, Liyuan Fu, Hairui Yu, Lu Wang, Lin Hou, Xing Yu, Zongyang An, Xuetong Wang, Lu Li, Yuanyuan Zhang, Peng Zhao, Qi Guo
OBJECTIVE: The objective of this study was to determine falls risk profiles to derive a falls risks prediction score and establish a simple and practical clinical screening tool for Chinese community-dwelling elderly individuals. METHOD: This was a prospective cohort study (N=619) among adults aged 60 years and older. Falls were ascertained at a 1-year follow-up appointment. Sociodemographic information, medical history and physical performance data were collected...
November 30, 2017: Rejuvenation Research
https://www.readbyqxmd.com/read/29190701/a-non-threshold-region-specific-method-for-detecting-rare-variants-in-complex-diseases
#11
Ai-Ru Hsieh, Dao-Peng Chen, Amrita Sengupta Chattopadhyay, Ying-Ju Li, Chien-Ching Chang, Cathy S J Fann
A region-specific method, NTR (non-threshold rare) variant detection method, was developed-it does not use the threshold for defining rare variants and accounts for directions of effects. NTR also considers linkage disequilibrium within the region and accommodates common and rare variants simultaneously. NTR weighs variants according to minor allele frequency and odds ratio to combine the effects of common and rare variants on disease occurrence into a single score and provides a test statistic to assess the significance of the score...
2017: PloS One
https://www.readbyqxmd.com/read/29189129/fdg-pet-ct-imaging-in-diabetic-patients-a-special-emphasis-on-imaging-of-infection
#12
Zohar Keidar
Nuclear Medicine (NM) imaging plays a major role in the assessment of infection and inflammation. Tracers, including single photon emitting radionuclides for single photon emission tomography (SPECT) and agents for positron emission tomography (PET), reflect primarily tissue and cellular function or metabolism. In the specific clinical setting of a patient with suspected infectious or inflammatory process, planar scintigraphy, SPECT or PET procedures are used to support a clinically suspected diagnosis. Integrating metabolic and anatomic information using a single SPECT/CT or PET/CT technique has substantially improved the diagnostic accuracy of these imaging tests and advanced the NM technology to be a significant and important tool in the field of infection and inflammation...
November 29, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29165880/hvidoere-smiley-faces-international-diabetes-quality-of-life-assessment-tool-for-young-children
#13
Hilary Hoey, Karin Lange, T C Skinner, Henrik Mortensen, Peter Swift, Henk-Jan Aanstoot, Luis Castaňo, Fergus Cameron, Carine de Beaufort
BACKGROUND: Few diabetes-specific quality of life (QOL) tools are available for young children. OBJECTIVES: To design and evaluate, a new age-specific QOL questionnaire and its associations with treatment regimens and metabolic control. METHODS: Clinical, demographic data and centrally analyzed HbA1c were collected on 1133 children <11 years (girls 48%; mean ± SD age 8.0 ± 2.1 years; diabetes duration ≥1 year) from 18 centers (Europe, Japan, North America and Australia)...
November 22, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/29157580/obstructive-sleep-apnea-and-diet-controlled-gestational-diabetes
#14
Ekasitt Wanitcharoenkul, Naricha Chirakalwasan, Somvang Amnakkittikul, Suranut Charoensri, Sunee Saetung, Suwannee Chanprasertyothin, La-Or Chailurkit, Panyu Panburana, Sommart Bumrungphuet, Boonsong Ongphiphadhanakul, Sirimon Reutrakul
BACKGROUND: Obstructive sleep apnea (OSA) was shown to be associated with gestational diabetes mellitus (GDM). However, prevalence of OSA in GDM women, its relationship to metabolic control, and predictive factors have not been studied. MATERIAL AND METHODS: Eighty-two obese pregnant women with diet-controlled GDM between 24 and 34 weeks of gestation participated. The Berlin questionnaire was used to assess OSA symptoms. OSA was diagnosed using an overnight monitor...
November 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29138275/enhanced-predictive-capability-of-a-1-hour-oral-glucose-tolerance-test-a-prospective-population-based-cohort-study
#15
Manan Pareek, Deepak L Bhatt, Mette L Nielsen, Ram Jagannathan, Karl-Fredrik Eriksson, Peter M Nilsson, Michael Bergman, Michael H Olsen
OBJECTIVE: To examine whether the 1-h blood glucose measurement would be a more suitable screening tool for assessing the risk of diabetes and its complications than the 2-h measurement. RESEARCH DESIGN AND METHODS: We conducted a prospective population-based cohort study of 4,867 men, randomly selected from prespecified birth cohorts between 1921 and 1949, who underwent an oral glucose tolerance test with blood glucose measurements at 0, 1, and 2 h. Subjects were followed for up to 39 years, with registry-based recording of events...
November 14, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29136281/genetic-prediction-of-type-2-diabetes-using-deep-neural-network
#16
J Kim, J Kim, M J Kwak, M Bajaj
Type 2 diabetes (T2DM) has strong heritability but genetic models to explain heritability have been challenging. We tested deep neural network (DNN) to predict T2DM using the nested case-control study of Nurses' Health Study (3,326 females, 45.6% T2DM) and Health Professionals Follow-up Study (2,502 males, 46.5% T2DM). We selected 96, 214, 399, and 678 SNPs through Fisher's exact test and L1-penalized logistic regression. We split each dataset randomly in 4:1 to train prediction models and test their performance...
November 14, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/29135052/enhanced-effect-of-human-mesenchymal-stem-cells-expressing-human-tnf-%C3%AE-r-fc-and-ho-1-gene-on-porcine-islet-xenotransplantation-in-humanized-mice
#17
Han-Sin Lee, Sanghyun Song, Du Yeon Shin, Geun-Soo Kim, Jong-Hyun Lee, Chan Woo Cho, Kyo Won Lee, Hyojun Park, Curie Ahn, Jaeseok Yang, Heung-Mo Yang, Jae Berm Park, Sung-Joo Kim
BACKGROUND: Porcine islet xenotransplantation is considered an attractive alternative treatment for type 1 diabetes mellitus. However, it is largely limited because of initial rejection due to Instant Blood-Mediated Inflammatory Reaction (IBMIR), oxidative stress, and inflammatory responses. Recently, soluble tumor necrosis factor-ɑ receptor type I (sTNF-αR) and heme oxygenase (HO)-1 genes (HO-1/sTNF-αR) have been shown to improve the viability and functionality of porcine islets after transplantation...
November 14, 2017: Xenotransplantation
https://www.readbyqxmd.com/read/29129000/health-literacy-in-type-2-diabetes-patients-a-systematic-review-of-systematic-reviews
#18
Rosario Caruso, Arianna Magon, Irene Baroni, Federica Dellafiore, Cristina Arrigoni, Francesco Pittella, Davide Ausili
Aim To summarize, critically review, and interpret the evidence related to the systematic reviews on health literacy (HL) amongst type 2 diabetes mellitus (T2DM). Methods The methodology for this study consisted of a systematic review of systematic reviews, using the PRISMA statement and flowchart to select studies, and searching on PubMed, CINAHL, Scopus, and Cochrane. The search covered the period between January 2006 and June 2016. Results From the 115 identified record by the queries, only six systematic reviews were included, following a quality evaluation using AMSTAR...
November 11, 2017: Acta Diabetologica
https://www.readbyqxmd.com/read/29125486/putative-dementia-cases-fluctuate-as-a-function-of-mini-mental-state-examination-cut-off-points
#19
Ilka M Rosa, Ana G Henriques, Jens Wiltfang, Odete A B da Cruz E Silva
As the population ages, there is a growing need to quickly and accurately identify putative dementia cases. Many cognitive tests are available; among those commonly used are the Cognitive Dementia Rating (CDR) and the Mini-Mental Status Examination (MMSE). The aim of this work was to compare the validity and reliability of these cognitive tests in a primary care based cohort (pcb-Cohort). The MMSE and the CDR were applied to 568 volunteers in the pcb-Cohort. Distinct cut-off points for the MMSE were considered, namely MMSE 27, MMSE 24, and MMSE PT (adapted for the Portuguese population)...
November 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29124943/simultaneous-inter-arm-and-inter-leg-systolic-blood-pressure-differences-to-diagnose-peripheral-artery-disease-a-diagnostic-accuracy-study
#20
Ángel Herráiz-Adillo, Alba Soriano-Cano, José Alberto Martínez-Hortelano, Miriam Garrido-Miguel, Julián Ángel Mariana-Herráiz, Vicente Martínez-Vizcaíno, Blanca Notario-Pacheco
PURPOSE: Inter-arm systolic blood pressure differences (IASBPD) and inter-leg systolic blood pressure differences (ILSBPD) have arisen as potential tools to detect peripheral artery disease (PAD) and individuals at high cardiovascular risk. This study aims to evaluate the diagnostic accuracy of IASBPD and ILSBPD to detect PAD, and whether IASBPD or ILSBPD improves diagnostic accuracy of the oscillometric ankle-brachial index (ABI). MATERIALS AND METHODS: In this prospective study, eligible for inclusion were consecutive adults, with at least one of the following cardiovascular risk factors: diabetes, dyslipidemia, hypertension, smoking habit or age ≥65...
November 10, 2017: Blood Pressure
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