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https://www.readbyqxmd.com/read/28733906/the-advanced-diarem-score-improves-prediction-of-diabetes-remission-1%C3%A2-year-post-roux-en-y-gastric-bypass
#1
Judith Aron-Wisnewsky, Nataliya Sokolovska, Yuejun Liu, Doron S Comaneshter, Shlomo Vinker, Tal Pecht, Christine Poitou, Jean-Michel Oppert, Jean-Luc Bouillot, Laurent Genser, Dror Dicker, Jean-Daniel Zucker, Assaf Rudich, Karine Clément
AIMS/HYPOTHESIS: Not all people with type 2 diabetes who undergo bariatric surgery achieve diabetes remission. Thus it is critical to develop methods for predicting outcomes that are applicable for clinical practice. The DiaRem score is relevant for predicting diabetes remission post-Roux-en-Y gastric bypass (RYGB), but it is not accurate for all individuals across the entire spectrum of scores. We aimed to develop an improved scoring system for predicting diabetes remission following RYGB (the Advanced-DiaRem [Ad-DiaRem])...
July 21, 2017: Diabetologia
https://www.readbyqxmd.com/read/28728577/integrating-data-from-randomized-controlled-trials-and-observational-studies-to-predict-the-response-to-pregabalin-in-patients-with-painful-diabetic-peripheral-neuropathy
#2
Joe Alexander, Roger A Edwards, Alberto Savoldelli, Luigi Manca, Roberto Grugni, Birol Emir, Ed Whalen, Stephen Watt, Marina Brodsky, Bruce Parsons
BACKGROUND: More patient-specific medical care is expected as more is learned about variations in patient responses to medical treatments. Analytical tools enable insights by linking treatment responses from different types of studies, such as randomized controlled trials (RCTs) and observational studies. Given the importance of evidence from both types of studies, our goal was to integrate these types of data into a single predictive platform to help predict response to pregabalin in individual patients with painful diabetic peripheral neuropathy (pDPN)...
July 20, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28726154/use-of-continuous-glucose-monitoring-in-youth-onset-type-2-diabetes
#3
REVIEW
Christine L Chan
PURPOSE OF REVIEW: Continuous glucose monitoring (CGM) technology has long been accepted as a tool for managing glycemia in type 1 diabetes (T1D) and is receiving increased attention as a tool for monitoring glucose patterns in patients with other forms of diabetes, in particular type 2 diabetes (T2D). Recent studies in adults with T2D have shown benefits of CGM in the investigation of glycemic variability, as well as utility as a tool for improving glycemic control. The literature on CGM use in youth-onset T2D, however, is sparse...
September 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28724059/screening-tests-for-distal-symmetrical-polyneuropathy-in-latin-american-patients-with-type-2-diabetes-mellitus
#4
Nicolás Gómez-Banoy, Virginia Cuevas, Fernando Soler, Maria Fernanda Pineda, Ismena Mockus
Objective: This cross sectional study intended to evaluate two bedside tests (Neuropad and VibraTip) as screening tools for distal symmetrical polyneuropathy (DSPN) in Latin American patients with type 2 diabetes mellitus (T2D). Subjects and methods: Ninety-three Colombian patients diagnosed with T2D were recruited. Anthropometric variables, glycemic control parameters, lipid profile and renal function were assessed for each patient. DSPN was defined by a Michigan Neuropathy Screening Instrument (MNSI) clinical score greater than 2...
July 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28714443/a-spanish-language-risk-perception-survey-for-developing-diabetes-translation-process-and-assessment-of-psychometric-properties
#5
Kevin L Joiner, Rosa Maria Sternberg, Christine Kennedy, Jyu-Lin Chen, Yoshimi Fukuoka, Susan L Janson
BACKGROUND AND PURPOSE: Create a Spanish-language version of the Risk Perception Survey for Developing Diabetes (RPS-DD) and assess psychometric properties. RESEARCH DESIGN AND METHODS: The Spanish-language version was created through translation, harmonization, and presentation to the tool's original author. It was field tested in a foreignborn Latino sample and properties evaluated in principal components analysis. RESULTS: Personal Control, Optimistic Bias, and Worry multi-item Likert subscale responses did not cluster together...
December 1, 2016: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28703868/cardiac-vagal-tone-a-non-invasive-measure-of-parasympathetic-tone-is-a-clinically-relevant-tool-in-type-1-diabetes-mellitus
#6
C Brock, N Jessen, B Brock, P E Jakobsen, T K Hansen, J M Rantanen, S Riahi, Y K Dimitrova, A Dons-Jensen, Q Aziz, A M Drewes, A D Farmer
AIMS: To compare a novel index of parasympathetic tone, cardiac vagal tone, with established autonomic variables and to test the hypotheses that (1) cardiac vagal tone would be associated with established time and frequency domain measures of heart rate and (2) cardiac vagal tone would be lower in people with Type 1 diabetes than in a matched healthy cohort and lower still in people with established neuropathy. METHODS: Cardiac vagal tone is a validated cardiometrically derived index of parasympathetic tone...
July 13, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28702090/translation-and-validation-of-diabetes-self-management-profile-dsmp-into-brazilian-portuguese-language-first-instrument-to-assess-type-1-diabetes-self-management-in-a-pediatric-population
#7
Caroline Gouveia Buff Passone, Lygia Spassapan Oliveira Esteves, Roberta Dias Savoldelli, Michael A Harris, Durval Damiani, Thais Della Manna
OBJECTIVE: To translate and validate the instrument Diabetes Self-Management Profile (DSMP)-Conventional and Flexible Regimens into Brazilian Portuguese language in order to evaluate the quality of diabetes self-management in children and adolescents with type 1 diabetes and their caregivers. METHODS: DSMP was submitted to forward and back translation method and validated in a group of type 1 diabetes youths between 6 and 18 years (n = 102), and their families...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28694205/association-of-variants-in-sh2b1-and-rabep1-with-worsening-of-low-density-lipoprotein-and-glucose-parameters-in-patients-treated-with-psychotropic-drugs
#8
Aurélie Delacrétaz, Adna Zdralovic, Frederik Vandenberghe, Nuria Saigi-Morgui, Anaïs Glatard, Lina Quteineh, Mehdi Gholam-Rezaee, Wassim Raffoul, Lee Ann Applegate, Paris Jafari, Franziska Gamma, Armin von Gunten, Philippe Conus, Chin B Eap
Genetic factors associated with Body Mass Index (BMI) have been widely studied over the last decade. We examined whether genetic variants previously associated with BMI in the general population are associated with cardiometabolic parameter worsening in the psychiatric population receiving psychotropic drugs, a high-risk group for metabolic disturbances. Classification And Regression Trees (CARTs) were used as a tool capable of describing hierarchical associations, to pinpoint genetic variants best predicting worsening of cardiometabolic parameters (i...
July 7, 2017: Gene
https://www.readbyqxmd.com/read/28692629/physical-activity-dimensions-associated-with-impaired-glucose-metabolism
#9
Hanan Amadid, Nanna B Johansen, Anne-Louise Bjerregaard, Dorte Vistisen, Kristine Færch, Søren Brage, Torsten Lauritzen, Daniel R Witte, Annelli Sandbæk, Marit E Jørgensen
PURPOSE: Physical activity (PA) is important in the prevention of type 2 diabetes, yet little is known about the role of specific dimensions of PA, including sedentary time in subgroups at risk of impaired glucose metabolism (IGM). We applied a data driven decision tool to identify dimensions of PA associated with IGM across age, sex and body mass index (BMI) groups. METHODS: This cross-sectional study included 1,501 individuals (mean (SD) age 65.6 (6.8) years) at high risk of type 2 diabetes from the ADDITION-PRO study...
July 7, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28690913/ghrelin-amylin-gastric-inhibitory-peptide-and-cognition-in-middle-aged-hiv-infected-and-uninfected-women-the-women-s-interagency-hiv-study
#10
Samy I McFarlane, Michelle M Mielke, Anthony Uglialoro, Sheila M Keating, Susan Holman, Howard Minkoff, Howard A Crystal, Deborah R Gustafson
OBJECTIVE: To explore the gut-brain axis by examining gut hormone levels and cognitive test scores in women with (HIV+) and without (HIV-) HIV infection. DESIGN/METHODS: Participants included 356 women (248 HIV+, 108 at risk HIV-) in the Brooklyn Women's Interagency HIV Study (WIHS) with measured levels of ghrelin, amylin and gastric inhibitory peptide (GIP), also known as glucose-dependent insulinotropic polypeptide. Cross-sectional analyses using linear regression models estimated the relationship between gut hormones and Trails A, Trails B, Stroop interference time, Stroop word recall, Stroop color naming and reading, and Symbol Digit Modalities Test (SDMT) with consideration for age, HIV infection status, Wide Range Achievement Test score (WRAT), CD4 count, insulin resistance, drug use, and race/ethnicity...
February 2017: Journal of Neurology & Neurophysiology
https://www.readbyqxmd.com/read/28689339/longitudinal-impact-of-a-park-based-afterschool-healthy-weight-program-on-modifiable-cardiovascular-disease-risk-factors-in-youth
#11
Sarah E Messiah, Emily M D'Agostino, Eric Hansen, M Sunil Mathew, Deidre Okeke, Maria Nardi, Jack Kardys, Kristopher L Arheart
Community-based programs hold significant potential to prevent cardiovascular disease (CVD) risk in youth. We describe here the longitudinal change in several modifiable CVD risk factors after participation in up to 3 years of Fit2Play™, a park-based afterschool program. Children ages 6-15 years old (N = 2261, mean age 9.0 years, 50% Hispanic, 47% non-Hispanic black, 54% male) who participated in Fit2Play™ for either 1-3 school years between 2010 and 2016 had height, weight, 4-site skinfold thicknesses, systolic and diastolic blood pressure, the progressive aerobic cardiovascular endurance run test, and health/wellness knowledge and behavior scores collected at the beginning and end of the school year(s)...
July 8, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28681942/time-to-glucose-peak-during-an-oral-glucose-tolerance-test-identifies-prediabetes-risk
#12
Stephanie T Chung, Joon Ha, Anthony U Onuzuruike, Kannan Kasturi, Mirella Galvan-De La Cruz, Brianna A Bingham, Rafeal L Baker, Jean N Utumatwishima, Lilian S Mabundo, Madia Ricks, Arthur S Sherman, Anne E Sumner
CONTEXT: Morphological characteristics of the glucose curve during an OGTT (time to peak and shape) may reflect different phenotypes of insulin secretion and action, but their ability to predict diabetes risk is uncertain. OBJECTIVE: To compare the ability of time to glucose peak and curve shape to detect prediabetes and β-cell function. DESIGN AND PARTICIPANTS: In a cross-sectional evaluation using an OGTT, 145 adults without diabetes (age 42±9y (mean±SD), range 24-62y, BMI 29...
July 6, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28678303/a-comparison-of-discovered-regularities-in-blood-glucose-readings-across-two-data-collection-approaches-used-with-a-type-1-diabetic-youth
#13
Victor Lee, Travis Thurston, Chris Thurston
BACKGROUND: Type 1 diabetes requires frequent testing and monitoring of blood glucose levels in order to determine appropriate type and dosage of insulin administration. This can lead to thousands of individual measurements over the course of a lifetime of a single individual, of which very few are retained as part of a permanent record. The third author, aged 9, and his family have maintained several years of written records since his diagnosis with Type 1 diabetes at age 20 months, and have also recently begun to obtain automated records from a continuous glucose monitor...
July 5, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28676311/the-seattle-spine-score-predicting-30-day-complication-risk-in-adult-spinal-deformity-surgery
#14
Quinlan D Buchlak, Vijay Yanamadala, Jean-Christophe Leveque, Alicia Edwards, Kellen Nold, Rajiv Sethi
BACKGROUND: Complication rates in complex spine surgery range from 25% to 80% in published studies. Numerous studies have shown that surgeons are not able to accurately predict whether patients are likely to face post-operative complications, in part due to biases based on individual experience. The purpose of this study was to develop and evaluate a predictive risk model and decision support system that could accurately predict the likelihood of 30-day postoperative complications in complex spine surgery based on routinely measured preoperative variables...
July 1, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28673573/exercise-for-type-1-diabetes-mellitus-management-general-considerations-and-new-directions
#15
Juliano Boufleur Farinha, Maurício Krause, Josianne Rodrigues-Krause, Alvaro Reischak-Oliveira
Type 1 diabetes mellitus (T1DM) is characterized by the loss of insulin secreting cells due to a directed autoimmune process, which is linked to oxidative stress and inflammation. Exercise training is known to induce several benefits by reducing inflammation and improving antioxidant defenses. In this context, exercise training may be considered as an efficient and relatively inexpensive non-pharmacological tool for diabetes treatment, added to the usual insulin administration. Unfortunately, most people with T1DM do not reach the recommended levels of physical activity due to concerns with hypoglycemic episodes...
July 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28670738/clinical-assessment-of-the-lag-time-and-tmax-of-pellets-with-controlled-release-of-glucose-in-vitro-in-vivo-comparison-using-13-c-breath-test
#16
David Neumann, Jan Muselík, Dana Sabadková, Sylvie Pavloková, Jana Špirková, Aleš Franc
Maintaining a stable glycemia in diabetes mellitus type 1 requires flexible insulin application and carbohydrates intake to affected individuals. In real life, there might be some situations limiting the insulin-sugar balance control, e.g. night sleep or prolonged sport activities. Glucose pellets with pre-determined time lag between pellet administration and glucose release were developed to mimic "snack eaten in advance". In this article, (13) C-glucose breath test is introduced to translate the laboratory dissolution testing to clinical confirmation of the glucose release pattern using 5 per cent of δ abundance to differentiate (13) C appearance in exhaled breath...
July 3, 2017: Biopharmaceutics & Drug Disposition
https://www.readbyqxmd.com/read/28669595/the-effect-of-educational-program-based-on-the-precede-proceed-model-on-improving-self-care-behaviors-in-a-semi-urban-population-with-type-2-diabetes-referred-to-health-centers-of-bavi-iran
#17
Neda Barasheh, Ghodratollah Shakerinejad, Sedigheh Nouhjah, Mohammad Hossein Haghighizadeh
AIMS: Self-care in patients with diabetes reduces the number of hospital admissions, costs and improves their quality of life so that just by training self-care to them can reduce 80 percent of diabetic complications. Therefore, this study aimed to investigate the effect of educational program based on precede-proceed model on improving self-care behaviors in patients with type 2 diabetes referred to health centers in city Bavi in 2016-2017. MATERIALS AND METHODS: This quasi-experimental study, conducted on 110 patient women with type 2 diabetes referred to health centers in Bavi city in 2016-2017...
June 23, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28668679/novel-application-of-published-risk-factors-for-methicillin-resistant-s-aureus-in-acute-bacterial-skin-and-skin-structure-infections
#18
Kimberly C Claeys, Evan J Zasowski, Abdalhamid M Lagnf, Donald P Levine, Susan L Davis, Michael J Rybak
MRSA ABSSSIs are associated with a significant clinical and economic burden, however rapid identification of MRSA remains a challenge. This study aimed to use a novel method of predictive modeling to determine those at highest risk of MRSA ABSSSIs. Risk factors for MRSA were derived from a combination of previously published literature and multivariable logistic regression of individual patient data (IPD) using the "adaptation method." A risk-scoring tool was derived from weight-proportional integer-adjusted coefficients of the predictive model...
June 28, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28653237/the-economic-burden-of-insulin-related-hypoglycemia-in-spain
#19
Witesh Parekh, Nicki Hoskins, James Baker-Knight, Antonio Ramirez de Arellano, Pedro Mezquita Raya
INTRODUCTION: An analysis was conducted to estimate the economic burden of insulin-related hypoglycemia in adults in Spain, derived from a novel concept developed for the UK known as the Local Impact of Hypoglycemia Tool. METHODS: Costs per severe and non-severe hypoglycemic episode were calculated for patients with type 1 diabetes (T1DM) and type 2 diabetes (T2DM). The costs per episode were applied to the population of adults with T1DM and T2DM using insulin in Spain according to the number of severe and non-severe episodes experienced per year...
June 26, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28651639/development-and-testing-of-a-mobile-application-to-support-diabetes-self-management-for-people-with-newly-diagnosed-type-2-diabetes-a-design-thinking-case-study
#20
Mira Petersen, Nana F Hempler
BACKGROUND: Numerous mobile applications have been developed to support diabetes-self-management. However, the majority of these applications lack a theoretical foundation and the involvement of people with diabetes during development. The aim of this study was to develop and test a mobile application (app) supporting diabetes self-management among people with newly diagnosed type 2 diabetes using design thinking. METHODS: The app was developed and tested in 2015 using a design-based research approach involving target users (individuals newly diagnosed with type 2 diabetes), research scientists, healthcare professionals, designers, and app developers...
June 26, 2017: BMC Medical Informatics and Decision Making
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