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Smoking and wbc count

Zhen-Wei Shen, Jie Xing, Qing-Lian Wang, Ali Faheem, Xiang Ji, Jie Li, Wei-Wei Bian, Zheng Jiang, Xiu-Jun Li, Fu-Zhong Xue, Jing Liu
PURPOSE: Limited numbers of literatures have focused on the association between γ-glutamyltransferase (GGT) and chronic kidney disease (CKD), and their results were controversial. Therefore, in this study, we set up a large-scale cohort of Chinese population to discover and verify the association between serum GGT and CKD. METHODS: Our cohort study was based on 21,818 patients who visited Health Management Center of Shandong Provincial Hospital, China, to receive routine health check-up during the period of 2005-2010, and we used multivariate Cox regression model to clarify whether elevated serum GGT increased the risk of CKD or not...
October 4, 2016: International Urology and Nephrology
Yufei Dai, Yong Niu, Huawei Duan, Bryan A Bassig, Meng Ye, Xiao Zhang, Tao Meng, Ping Bin, Xiaowei Jia, Meili Shen, Rong Zhang, Wei Hu, Xiaofa Yang, Roel Vermeulen, Debra Silverman, Nathaniel Rothman, Qing Lan, Shanfa Yu, Yuxin Zheng
The International Agency for Research on Cancer has classified carbon black (CB) as a possible (Group 2B) human carcinogen. Given that most CB manufacturing processes result in the emission of various types of chemicals, it is uncertain if the adverse health effects that have been observed in CB-exposed workers are related to CB specifically or are due to other exposures. To address this issue, we conducted a cross-sectional molecular epidemiology study in China of 106 male factory workers who were occupationally exposed to pure CB and 112 unexposed male workers frequency-matched by age and smoking status from the same geographic region...
October 2016: Environmental and Molecular Mutagenesis
Bartłomiej Górski, Ewa Nargiełło, Grzegorz Opolski, Ewa Ganowicz, Renata Górska
BACKGROUND: Many epidemiological studies have proven that local infection may influence the levels of systemic lipid profile and inflammatory mediators. OBJECTIVES: The aim of this research was to evaluate the association between the state of the oral cavity, lipids and inflammatory mediator concentrations in Poles after acute myocardial infarction (MI). MATERIAL AND METHODS: A total of 134 subjects with a mean age of 54.3 years (± 8.1) were included in the study...
July 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Takakazu Higuchi, Fumio Omata, Kenji Tsuchihashi, Kazuhiko Higashioka, Ryosuke Koyamada, Sadamu Okada
While cigarette smoking is a well-recognized cause of elevated white blood cell (WBC) count, studies on longitudinal effect of smoking cessation on WBC count are limited. We attempted to determine causal relationships between smoking and elevated WBC count by retrospective cross-sectional study consisting of 37,972 healthy Japanese adults who had a health check-up between April 1, 2008 and March 31, 2009 and longitudinal study involving 1730 current smokers who had more than four consecutive annual health check-ups between April 1, 2007 and March 31, 2012...
December 2016: Preventive Medicine Reports
Kyu Rae Lee, Ki Dong Ko, In Cheol Hwang, Heuy Sun Suh, Kyoung Kon Kim
OBJECTIVE: The Korea National Health and Nutrition Examination Survey (KNHANES) has been performed every 3 years in Korea to help prevent cardiovascular mortality in the general population. Previous studies showed an association between blood lead levels and cardiovascular mortality. In order to assess the relationship between blood lead concentration and blood pressure in the healthy general population, we investigated whether blood lead levels were related to blood pressure in a non-smoking healthy population without any known medical diseases in the 2013 KNHANES...
August 23, 2016: Postgraduate Medical Journal
Hans Mouser, Frank H Miller, Senta M Berggruen
History A 35-year-old man from the upper Midwest region of the United States who had no relevant medical history initially presented to an acute care clinic with multiple small tender skin lesions. His temperature was 38.1°C, and physical examination revealed several small fluctuant masses that were draining purulent material. Skin culture of one of the draining lesions was performed at this time, but there was no subsequent bacterial growth. A diagnosis of furunculosis was made, and Bactrim (sulfamethoxazole-trimethoprim; AR Scientific, Philadelphia, Pa) and a regimen of chlorhexidine washes were prescribed...
September 2016: Radiology
Gunnar Gudmundsson, Olof Birna Margretardottir, Martin Ingi Sigurdsson, Tamara B Harris, Lenore J Launer, Sigurdur Sigurdsson, Orn Olafsson, Thor Aspelund, Vilmundur Gudnason
BACKGROUND AND AIMS: Airflow limitation, i.e. reduced forced expiratory volume in 1-s (FEV1), is associated with increased prevalence of atherosclerosis, however, causal mechanisms remain elusive. The objective of the study was to determine if the association between airflow obstruction and markers of atherosclerosis is mediated by systemic inflammation. METHODS: 1154 subjects from the longitudinal AGES Reykjavik study were included. Population characteristics, systemic inflammation markers from blood (white blood cell counts (WBC) and level of C-reactive protein (CRP)) were compared between patients with and without airflow limitation defined by reduced FEV1 on spirometry...
September 2016: Atherosclerosis
Sasa Dusanov, Eli Heggen, Serena Tonstad
BACKGROUND: Metabolic syndrome (MetSyn) magnifies risks of cardiovascular disease (CVD) and type 2 diabetes, but its expression varies within the obese population. We examined body mass index (BMI), metabolic traits, and fat distribution in morbidly obese individuals. METHODS: Lipids and inflammatory, oxidative stress and hepatic biomarkers in 346 women and 203 men (BMI ≥35 kg/m(2) and co-morbidity or ≥40 kg/m(2)) were stratified by MetSyn components (1-5, excluding diabetes)...
August 11, 2016: Metabolic Syndrome and related Disorders
Emin Ozlu, Ayse Serap Karadag, Aybala E Toprak, Tugba K Uzuncakmak, Fethullah Gerin, Feyza Aksu, Ozlem Ozakpınar, Necmettin Akdeniz
BACKGROUND AND OBJECTIVE: The current study aimed to evaluate cardiovascular risk factors, haematological and biochemical parameters, and serum endocan concentrations in lichen planus (LP) patients. METHODS: This study was conducted with 86 cases, including 43 LP patients and 43 healthy controls. Cardiovascular risk factors, haematological and biochemical parameters, and endocan levels were evaluated. RESULTS: The serum endocan concentrations of LP patients were not significantly different from those of the healthy controls (p > 0...
2016: Dermatology: International Journal for Clinical and Investigative Dermatology
Y K Tulgar, S Cakar, S Tulgar, O Dalkilic, B Cakiroglu, B S Uyanik
OBJECTIVE: Smoking commonly leads to death. Although the neutrophil/lymphocyte Ratio, platelet/lymphocyte ratio and platelet indices have been shown to be important for the diagnosis, prognosis and severity of some diseases, the smoking status of patients in these studies has not been well defined. In this study, we compared ratios derived from complete blood count and platelet indices to smoking status and length in smokers and non-smokers. PATIENTS AND METHODS: The data of healthy males and females aged between 18-60 years who presented to our institute for a routine check-up were collected, and subjects were divided in two groups - smokers and non-smokers...
July 2016: European Review for Medical and Pharmacological Sciences
M Petersen, R Steinert, O Jannasch, M Venerito, C Meissner, S Kropf, R Albrecht, H Lippert, F Meyer
PURPOSE: In hepatic resections, there has been a high quality demand. The aim of this systematic clinical, prospective, unblinded unicenter observational study with two arms in an unselected patient cohort was to investigate whether hemostat device can significantly improve outcome in resective liver surgery, in particular, in high risk patients. METHODS: All consecutive patients (mean age, 60.5 [range, 17 - 96] years) who underwent hepatic resection (ntotal = 770) were prospectively documented in a computer-based registry at a university hospital (tertiary center) over a time period of 10 years and retrospectively evaluated specifically with regard to the use (-/+; in daily practice and intraoperative decision-making) of hemostat device (Tissucol(®), n = 59/Tachocomb(®), n = 202/combination, n = 55) indicated (among others) by drainage volume, inflammatory parameters and rate of specific complications (nvalidated = 541 [100 %])...
July 2016: Zeitschrift Für Gastroenterologie
Kyungdo Han, Eunkyung Hwang, Jun-Beom Park
This study was performed to assess the relationship between the amount of green tea that is consumed and periodontitis. It is based on data obtained from the Korea National Health and Nutrition Examination Survey, conducted between 2008 and 2010. A community periodontal index equal to code 3 was defined as moderate periodontitis, and code 4 was defined as severe periodontitis (n = 16,726). Consumption of green tea less than one cup per day was associated with a decreased prevalence of periodontal disease among Korean adults...
2016: Nutrients
Yun-Mi Song, Joohon Sung, Kayoung Lee
BACKGROUND: This study aimed to evaluate genetic and environmental relations between change in estimated glomerular filtration rate (eGFR) and changes in cardiometabolic factors. METHODS: In 1772 Korean adults without diabetes and chronic kidney disease at baseline, changes in eGFR using the Chronic Kidney Disease Epidemiology Collaboration equation, blood pressure (BP), fasting serum glucose (FSG), insulin, homeostasis model assessment of insulin resistance index (HOMA-IR), hemoglobin A1c, triglycerides, high and low density lipoprotein cholesterol (HDL and LDL), uric acid, white blood cell (WBC) count, and body mass index (BMI) were calculated as follows: (value at follow-up - value at baseline) × 100/[value at baseline × follow-up interval (years)]...
June 23, 2016: Clinical and Experimental Nephrology
Takeshi Miyayama, Shin-Ichiro Miura, Tomo Komaki, Takashi Kuwano, Joji Morii, Hiroaki Nishikawa, Keijiro Saku
A 26-year-old male suffered sustained chest pain. Electrocardiogram showed ST-segment elevation in the anteroseptal wall and reciprocal ST-segment change in the inferior wall. The troponin-I level and the white blood cell count were elevated. We gave a diagnosis of acute myocardial infarction. He underwent urgent coronary angiography, which revealed 90% diffuse stenosis in the middle right coronary artery and total occlusion in the proximal left anterior descending coronary artery (LAD). Since the electrocardiogram indicated that the culprit lesion was in the proximal LAD, we performed percutaneous coronary intervention...
July 2016: Journal of Clinical Medicine Research
Jia Sun, Jonas Axelsson, Anna Machowska, Olof Heimbürger, Peter Bárány, Bengt Lindholm, Karin Lindström, Peter Stenvinkel, Abdul Rashid Qureshi
BACKGROUND AND OBJECTIVES: The high risk of cardiovascular disease (CVD) and premature death in patients with CKD associates with a plethora of elevated circulating biomarkers that may reflect distinct signaling pathways or simply, are epiphenomena of CKD. We compared the predictive strength of 12 biomarkers analyzed concomitantly in patients with stage 5 CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: From 1994 to 2014, 543 patients with stage 5 CKD (median age =56 years old; 63% men; 199 patients had CVD) took part in our study on malnutrition, inflammation, and CVD in incident dialysis patients...
July 7, 2016: Clinical Journal of the American Society of Nephrology: CJASN
Kenji Obayashi, Keigo Saeki, Norio Kurumatani
Chronic low-grade systemic inflammation increases cardiovascular risk and mortality. Subjective assessment of sleep quality in previous observational studies has demonstrated associations with biomarkers of systemic inflammation, although the results are conflicting. In this cross-sectional study on 1098 elderly individuals, circulating white blood cell (WBC) count and actigraphic sleep quality were measured as indices of systemic inflammation and objective sleep quality, respectively. Lower sleep efficiency (SE) and longer wake after sleep onset (WASO) were significantly associated with increased WBC count in females (n=581) but no significant associations were observed in the association between WBC count and all objective sleep parameters in males (n=517)...
October 1, 2016: Physiology & Behavior
Rajini Kurup, Keon Flemming, Sudish Daniram, Shenika Marks-James, Roberta Roberts Martin
Objective. To evaluate the hematological and biochemistry profile of patients with or without HIV-TB at the Georgetown Chest Clinic, Guyana. Methods. An observational, laboratory based study was designed to assess the relationship of PTB and HIV with patients routine biochemical and hematological values. The study was conducted during the period January 2013 to December 2014; a total sample size of 316 patients was enrolled following exclusion and inclusion criteria. Results. Mean age of study population was 40...
2016: Tuberculosis Research and Treatment
Bethany Lowndes, Cornelius A Thiels, Elizabeth B Habermann, Juliane Bingener, Susan Hallbeck, Denny Yu
BACKGROUND: Patient factors impact laparoscopic cholecystectomy (LC) difficulty, specifically operative duration. This study quantifies the impact of patient factors on LC duration. METHODS: The national surgery database (American College of Surgeons National Surgical Quality Improvement Program) was reviewed for all elective LC for biliary colic from 2005 to 2013. Multivariate general linear model and logistic regression were used to evaluate patient factors as predictors of operative duration greater than 60 minutes, adjusted for resident involvement and cholangiography...
August 2016: American Journal of Surgery
M Panova-Noeva, I M Hermanns, A Schulz, D Laubert-Reh, T Zeller, S Blankenberg, H M Spronk, T Münzel, K J Lackner, H Ten Cate, P S Wild
INTRODUCTION: The advancements in cancer treatment and detection of early cancer have resulted in steady increase of adult cancer survivors over the years. However, due to the long term toxic effects of chemotherapy and radiotherapy, the incidence of cardiovascular diseases (CVD) is increasing in survivors. Identifying risk factors and interventions to reduce the excess burden of CVD in this vulnerable population is urgently needed. AIM: To investigate the cardiovascular risk factors (CVRFs), inflammation and coagulation profile in cancer survivors from a large population-based study...
April 2016: Thrombosis Research
Hanne M Frøyshov, Åshild Bjørnerem, Torgeir Engstad, Dag Seeger Halvorsen
BACKGROUND AND AIMS: High levels of inflammatory markers shortly after an ischemic stroke are associated with a worse prognosis. Whether inflammatory markers predict long-term mortality in stroke-survivors is less clear. We examined whether a persisting inflammatory response (levels of inflammatory markers >1 year after the stroke event) was associated with long-term mortality. METHODS: We recruited participants from the Tromsø Study, Norway, in a nested case-control design...
May 4, 2016: Aging Clinical and Experimental Research
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