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https://www.readbyqxmd.com/read/29223110/systemic-inflammatory-markers-associated-with-cardiovascular-disease-and-acute-and-chronic-exposure-to-fine-particulate-matter-air-pollution-pm2-5-among-us-nhanes-adults-with-metabolic-syndrome
#1
Arvind Dabass, Evelyn O Talbott, Judith R Rager, Gary M Marsh, Arvind Venkat, Fernando Holguin, Ravi K Sharma
BACKGROUND: There has been no investigation to date of adults with metabolic syndrome examining the association of short and long-term exposure to fine particulate matter (PM2.5) air pollution with cardiovascular-disease related inflammatory marker (WBC and CRP) levels in a nationally representative sample. The goal of this study is to assess the susceptibility of adults with metabolic syndrome to PM2.5 exposure as suggested by increased cardiovascular-disease related inflammatory marker levels...
December 6, 2017: Environmental Research
https://www.readbyqxmd.com/read/29212563/clinically-relevant-and-simple-immune-system-measure-is-related-to-symptom-burden-in-bipolar-disorder
#2
Ole Köhler-Forsberg, Louisa Sylvia, Thilo Deckersbach, Michael Joshua Ostacher, Melvin McInnis, Dan Iosifescu, Charles Bowden, Susan McElroy, Joseph Calabrese, Michael Thase, Richard Charles Shelton, Mauricio Tohen, James Kocsis, Edward Friedman, Terence Ketter, Andrew Alan Nierenberg
OBJECTIVE: Immunological theories, particularly the sickness syndrome theory, may explain psychopathology in mood disorders. However, no clinical trials have investigated the association between overall immune system markers with a wide range of specific symptoms including potential gender differences. METHODS: We included two similar clinical trials, the lithium treatment moderate-dose use study and clinical and health outcomes initiatives in comparative effectiveness for bipolar disorder study, enrolling 765 participants with bipolar disorder...
December 7, 2017: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/29155119/high-serum-bilirubin-is-associated-with-lower-prevalence-of-peripheral-arterial-disease-among-cardiac-patients
#3
Michishige Ozeki, Hideaki Morita, Masatoshi Miyamura, Tomohiro Fujisaka, Shu-Ichi Fujita, Takahide Ito, Kensaku Shibata, Suguru Tanaka, Koichi Sohmiya, Masaaki Hoshiga, Nobukazu Ishizaka
Several studies have shown that subjects with higher serum bilirubin may have a lower risk of cardiovascular disorders. We herein investigated whether serum bilirubin concentration is associated with lower extremity ischemia among cardiology patients. In total, 935 patients without a history of angioplasty or bypass surgery of the lower limb arteries and who had bilateral ankle-brachial index measurements were included in the study. Peripheral arterial disease (PAD) was defined to be present when ABI of either or both sides was <0...
November 18, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29121708/factors-associated-with-a-prolonged-length-of-hospital-stay-in-patients-with-diabetic-foot-a-single-center-retrospective-study
#4
Sang Kyu Choi, Cheol Keun Kim, Dong In Jo, Myung Chul Lee, Jee Nam Kim, Hyun Gon Choi, Dong Hyeok Shin, Soon Heum Kim
BACKGROUND: We conducted this study to identify factors that may prolong the length of the hospital stay (LHS) in patients with diabetic foot (DF) in a single-institution setting. METHODS: In this single-center retrospective study, we evaluated a total of 164 patients with DF, and conducted an intergroup comparison of their baseline demographic and clinical characteristics, including sex, age, duration of diabetes, smoking status, body mass index, underlying comorbidities (e...
November 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29113395/association-between-fibrinogen-level-and-the-severity-of-coronary-stenosis-in-418-male-patients-with-myocardial-infarction-younger-than-35-years-old
#5
Xiong-Yi Gao, Bing-Yang Zhou, Min-Zhou Zhang, Xi Zhao, Ping Qing, Cheng-Gang Zhu, Na-Qiong Wu, Yuan-Lin Guo, Ying Gao, Xiao-Lin Li, Yao Wang, Geng Liu, Qian Dong, Li-Heng Guo, Jian-Jun Li
Fibrinogen (Fib) is a useful marker for predicting the severity of coronary artery disease (CAD) in adult population. However, whether Fib can be a predictor for the presence and severity of CAD in very young MI patients (≤35 years old) remains to be determined. A total of 418 males from 61,863 patients with MI who were under 35 years old were sequentially recruited in our study. The patients were divided into two main groups and three subgroups according to coronary angiograph and Gensini score (GS) system: no coronary artery stenosis (group A), the results of the coronary artery stenosis (group B); low GS, intermediate GS and high GS...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/29056349/clinical-characteristics-of-spontaneous-isolated-visceral-artery-dissection
#6
Yoshihiro Tanaka, Tsuyoshi Yoshimuta, Keiichi Kimura, Kenji Iino, Yudai Tamura, Kenji Sakata, Kenshi Hayashi, Hirofumi Takemura, Masakazu Yamagishi, Masa-Aki Kawashiri
OBJECTIVE: Spontaneous isolated visceral artery dissection (SIVAD) involving the celiac artery or superior mesenteric artery is rare, but it can be fatal. Given its rare incidence, the clinical characteristics of SIVAD are not fully understood. Therefore, the aim of this study was to investigate the clinical characteristics and prognosis of SIVAD. METHODS: We retrospectively reviewed 39 consecutive patients diagnosed with SIVAD from January 2007 to December 2016...
October 19, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28956553/benzene-exposure-from-the-bp-refinery-flaring-incident-alters-hematological-and-hepatic-functions-among-smoking-subjects
#7
Mark A D'Andrea, G Kesava Reddy
OBJECTIVES: To evaluate the health effects of benzene exposure among smoking subjects from a prolonged flaring incident that occurred at the British Petroleum (BP) refinery in Texas City, USA. MATERIAL AND METHODS: The study included smoking subjects who had been exposed and unexposed to the benzene release. Using medical charts, clinical data including white blood cell (WBC) counts, platelet counts, hemoglobin, hematocrit, blood urea nitrogen (BUN), creatinine, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) in the case of smoking subjects exposed to benzene was reviewed and analyzed...
September 27, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28942957/increased-circulating-blood-cell-counts-in-combat-related-ptsd-associations-with-inflammation-and-ptsd-severity
#8
Daniel Lindqvist, Synthia H Mellon, Firdaus S Dhabhar, Rachel Yehuda, S Marlene Grenon, Janine D Flory, Linda M Bierer, Duna Abu-Amara, Michelle Coy, Iouri Makotkine, Victor I Reus, Kirstin Aschbacher, F Saverio Bersani, Charles R Marmar, Owen M Wolkowitz
Inflammation is reported in post-traumatic stress disorder (PTSD). Few studies have investigated circulating blood cells that may contribute to inflammation. We assessed circulating platelets, white blood cells (WBC) and red blood cells (RBC) in PTSD and assessed their relationship to inflammation and symptom severity. One-hundred and sixty-three male combat-exposed veterans (82 PTSD, 81 non-PTSD) had blood assessed for platelets, WBC, and RBC. Data were correlated with symptom severity and inflammation. All cell counts were significantly elevated in PTSD...
December 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28910242/how-does-the-social-get-under-the-gums-the-role-of-socio-economic-position-in-the-oral-systemic-health-link
#9
Noha Gomaa, Belinda Nicolau, Arjumand Siddiqi, Howard Tenenbaum, Michael Glogauer, Carlos Quiñonez
OBJECTIVES: To evaluate the extent of association between systemic inflammation and periodontal disease in American adults, and to assess whether socio-economic position mediated this relationship. METHODS: We used data from the National Health and Nutrition Examination Survey (NHANES IV) (2001-2010). Systemic inflammation was defined by individual and aggregate (cumulative inflammatory load) biomarkers (C-reactive protein, white blood cell counts, neutrophil counts, and neutrophil:lymphocyte ratio)...
September 14, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28886262/effectiveness-of-antibiotic-treatment-in-infertile-patients-with-sterile-leukocytospermia-induced-by-tobacco-use
#10
Bogdan Pajovic, Ljiljana Pajovic, Marko Vukovic
Our study investigated whether antibiotic therapy in infertile tobacco users with sterile leukocytospermia and a history of former sexual transmitted disease (STD) has an advantage over cessation of smoking alone. For this study, 80 male infertile smokers were divided into two subgroups. The first group numbered 40 patients treated with a two week course of doxycycline, 100 mg, twice daily, while the second group simply ceased smoking. A control group of 20 patients with chronic abacterial prostatitis (CPPS III a) were treated with the same antibiotic for two weeks...
September 8, 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28790546/effect-of-cigarette-smoking-on-haematological-parameters-in-healthy-population
#11
Maja Malenica, Besim Prnjavorac, Tamer Bego, Tanja Dujic, Sabina Semiz, Selma Skrbo, Amar Gusic, Ajla Hadzic, Adlija Causevic
OBJECTIVE: Tobacco cigarette smoking is one of the major leading causes of death throughout the world. Smoking has both acute and chronic effect on haematological parameters. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics in healthy smokers. SUBJECTS AND METHOD: One hundred and fifty six subjects participated in this study, 56 smokers and 100 non-smokers. The smokers were regularly consuming 10-20 cigarettes per day for at least 3 years...
April 2017: Medical Archives
https://www.readbyqxmd.com/read/28747965/systemic-white-blood-cell-count-as-a-biomarker-associated-with-severity-of-chronic-obstructive-lung-disease
#12
Hyeon-Kyoung Koo, Hyung Koo Kang, Pamela Song, Hye Kyeong Park, Sung-Soon Lee, Hoon Jung
BACKGROUND: Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, is associated with the severity of COPD, independent of other inflammatory conditions, such as metabolic syndrome. METHODS: The WBC counts were compared between 1227 COPD patients and 8679 non-COPD adults older than 40. The relationships between the WBC count, lung function, and symptoms score in COPD patients, were determined, using general linear regression analyses...
July 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28747453/serum-matrix-metalloproteinase-9-levels-and-prognosis-of-acute-ischemic-stroke
#13
RANDOMIZED CONTROLLED TRIAL
Chongke Zhong, Jingyuan Yang, Tan Xu, Tian Xu, Yanbo Peng, Aili Wang, Jinchao Wang, Hao Peng, Qunwei Li, Zhong Ju, Deqin Geng, Yonghong Zhang, Jiang He
OBJECTIVE: To examine the association between serum matrix metalloproteinases-9 (MMP-9) levels and prognosis of acute ischemic stroke. METHODS: We measured serum MMP-9 levels in 3,186 participants (2,008 men and 1,178 women) from the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS). Study outcome data on death, major disability (modified Rankin Scale score ≥3), and vascular disease were collected at 3 months after stroke onset. RESULTS: During 3 months of follow-up, 767 participants (24...
August 22, 2017: Neurology
https://www.readbyqxmd.com/read/28733767/relationship-between-plasma-pentraxin-3-level-and-risk-of-chronic-kidney-disease-in-the-korean-elderly-the-dong-gu-study
#14
Ran Lee, Min-Ho Shin, Hee-Nam Kim, Young-Hoon Lee, Seong-Woo Choi, Hye-Ran Ahn, Sun-Seog Kweon
Purpose This study investigated the cross-sectional association between chronic kidney disease (CKD) and plasma pentraxin 3 (PTX3) levels in a Korean population, in a community-based cohort study. METHODS: A total of 1816 (891 men, 925 women) subjects were randomly selected from the cohort of participants for the final analyses. Plasma PTX3 concentration was determined using enzyme-linked immunosorbent assays. The participants were divided into four quartiles according to the PTX3 levels...
November 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28644146/association-between-fibrinogen-level-and-the-severity-of-coronary-stenosis-in-418-male-patients-with-myocardial-infarction-younger-than-35-years-old
#15
Xiong-Yi Gao, Bing-Yang Zhou, Min-Zhou Zhang, Xi Zhao, Ping Qing, Cheng-Gang Zhu, Na-Qiong Wu, Yuan-Lin Guo, Ying Gao, Xiao-Lin Li, Yao Wang, Geng Liu, Qian Dong, Li-Heng Guo, Jian-Jun Li
Fibrinogen (Fib) is a useful marker for predicting the severity of coronary artery disease (CAD) in adult population. However, whether Fib can be a predictor for the presence and severity of CAD in very young MI patients (≤35 years old) remains to be determined. A total of 418 males from 61,863 patients with MI who were under 35 years old were sequentially recruited in our study. The patients were divided into two main groups and three subgroups according to coronary angiograph and Gensini score (GS) system: no coronary artery stenosis (group A), the results of the coronary artery stenosis (group B); low GS, intermediate GS and high GS...
June 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/28638984/associations-of-aldosterone-and-renin-concentrations-with-inflammation-the-study-of-health-in-pomerania-and-the-german-conn-s-registry
#16
A Grotevendt, H Wallaschofski, M Reincke, C Adolf, M Quinkler, M Nauck, W Hoffmann, R Rettig, A Hannemann
PURPOSE: Chronic inflammation is an age-independent and body mass index-independent contributor to the development of multi-morbidity. Alterations of the renin-angiotensin-aldosterone system are observed within the context of proinflammatory states. We assessed circulating aldosterone, renin, and inflammatory biomarker concentrations in healthy, normotensive subjects and patients with primary aldosteronism. METHODS: We included 1177 normotensive individuals from the population-based Study of Health in Pomerania (first follow-up, Study of Health in Pomerania-1) and 103 primary aldosteronism patients from the German Conn's Registry...
August 2017: Endocrine
https://www.readbyqxmd.com/read/28625128/the-wnt-%C3%AE-catenin-signalling-pathway-inhibitor-sclerostin-is-a-biomarker-for-early-atherosclerosis-in-obesity
#17
Djordje S Popovic, Milena Mitrovic, Dragana Tomic-Naglic, Tijana Icin, Ivana Bajkin, Bojan Vukovic, Damir Benc, Zeljko Zivanovic, Branka Kovacev-Zavisic, Edita Stokic
BACKGROUND: Sclerostin is an inhibitor of the wingless-type mouse mammary tumor virus integration site family/β-catenin signalling pathway (WβcSP), which plays an important role in bone metabolism and in vascular biology. It could act protective regarding atherosclerosis development through its effect on WβcSP in vascular cells. Nevertheless, results of studies analyzing association between circulating sclerostin level (CSL) and atherosclerotic diseases (AD) are showing conflicting results...
2017: Current Neurovascular Research
https://www.readbyqxmd.com/read/28620476/vitamin-d-and-inflammatory-markers-cross-sectional-analyses-using-data-from-the-english-longitudinal-study-of-ageing-elsa
#18
Cesar de Oliveira, Jane P Biddulph, Vasant Hirani, Ione Jayce Ceola Schneider
Recent evidence suggests that low vitamin D concentrations are associated with increased levels of inflammatory markers. However, there are limited studies investigating associations between vitamin D levels and inflammatory markers in the general population and much of this evidence in older adults is inconclusive. Therefore, this study investigates the cross-sectional association of serum 25-hydroxyvitamin D (25(OH)D) levels with inflammatory markers in 5870 older English adults from wave 6 (2012-2013) of the English Longitudinal Study of Ageing (ELSA)...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28576612/evaluation-of-an-association-between-long-sleep-duration-and-periodontal-disease-among-men-and-women-using-nationally-representative-data
#19
Kyungdo Han, Yong-Moon Park, Jun-Beom Park
OBJECTIVE: To assess the association between long sleep duration and periodontal disease among men and women using nationally representative data. METHODS: In this study, we performed a cross-sectional analysis and used multivariable logistic regression analysis models. We analysed data from 2012 through 2014 from the Korean National Health and Nutrition Examination Survey. The analysis in this study was confined to a total of 14,675 respondents over 19 years of age...
May 30, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28496956/effects-of-opium-addiction-and-cigarette-smoking-on-hematological-parameters
#20
Gholamabbas Shahabinejad, Majid Sirati-Sabet, Mohammad Kazemi-Arababadi, Saeideh Nabati, Gholamreza Asadikaram
BACKGROUND: The aim of the present study was to investigate the effects of opium addiction and cigarette smoking on the complete blood count (CBC). METHODS: Eighty-six male subjects, including 31 opium-addicted cigarette smokers (OACS), 19 opium-addicted non-cigarette smokers (OANCS), 17 non-opium-addicted cigarette smokers (NOACS), and 19 non-opium-addicted non-cigarette smokers (NOANCS) participated in this study. The CBC test was measured in all individuals. FINDINGS: The OACS had significantly higher white blood cell (WBC), lymphocyte, and red blood cell (RBC) count but lower in mean corpuscular volume (MCV) compared to NOANCS...
July 2016: Addiction & Health
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