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Smoking and wbc count

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https://www.readbyqxmd.com/read/28496956/effects-of-opium-addiction-and-cigarette-smoking-on-hematological-parameters
#1
Gholamabbas Shahabinejad, Majid Sirati-Sabet, Mohammad Kazemi-Arababadi, Saeideh Nabati, Gholamreza Asadikaram
BACKGROUND: The aim of the present study was to investigate the effects of opium addiction and cigarette smoking on the complete blood count (CBC). METHODS: Eighty-six male subjects, including 31 opium-addicted cigarette smokers (OACS), 19 opium-addicted non-cigarette smokers (OANCS), 17 non-opium-addicted cigarette smokers (NOACS), and 19 non-opium-addicted non-cigarette smokers (NOANCS) participated in this study. The CBC test was measured in all individuals. FINDINGS: The OACS had significantly higher white blood cell (WBC), lymphocyte, and red blood cell (RBC) count but lower in mean corpuscular volume (MCV) compared to NOANCS...
July 2016: Addiction & Health
https://www.readbyqxmd.com/read/28490753/wbc-count-predicts-the-risk-of-new-onset-peripheral-arterial-disease-in-a-chinese-community-based-population
#2
Yuxi Li, Fangfang Fan, Jia Jia, Jianping Li, Yong Huo, Yan Zhang
This longitudinal cohort study investigated whether peripheral WBC counts could predict peripheral arterial disease (PAD) incidence after a 2.3-year follow-up in a Chinese community-based population without PAD at baseline. A total of 3555 Chinese subjects without fever and PAD at baseline from an atherosclerosis cohort were included in our analysis. The ankle brachial index (ABI) was measured, and PAD was defined as an ABI <0.9. Multivariate regression models were used to evaluate the association of WBC count and new-onset PAD...
May 11, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28488901/association-of-shiftwork-and-immune-cells-among-police-officers-from-the-buffalo-cardio-metabolic-occupational-police-stress-study
#3
Michael D Wirth, Michael E Andrew, Cecil M Burchfiel, James B Burch, Desta Fekedulegn, Tara A Hartley, Luenda E Charles, John M Violanti
Shift workers suffer from a constellation of symptoms associated with disruption of circadian rhythms including sleep abnormalities, and abnormal hormone secretion (e.g. melatonin, cortisol). Recent, but limited, evidence suggests that shift workers have elevated levels of circulating white blood cells (WBCs) compared to their day working counterparts. Interestingly, recent reviews highlight the strong linkage between the immune system and circadian rhythms which includes, but is not limited to, circulating cell populations and functions...
May 10, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28449059/marijuana-use-impacts-midlife-cardiovascular-events-in-hiv-infected-men
#4
David R Lorenz, Anupriya Dutta, Shibani S Mukerji, Alex Holman, Hajime Uno, Dana Gabuzda
Background.: Marijuana use is prevalent among persons infected with HIV, but its long-term effects on HIV disease progression and comorbidities are unknown. Methods.: A prospective study of 558 HIV-infected men enrolled in the Multicenter AIDS Cohort Study between 1990-2010: 182 HIV seroconverters and 376 with viral suppression on combination antiretroviral therapy (ART). Associations between heavy marijuana use and HIV disease markers or white blood cell (WBC) count were examined using mixed-effects and linear regression models...
April 25, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28448810/associations-between-blood-btexs-concentrations-and-hematologic-parameters-among-adult-residents-of-the-u-s-gulf-states
#5
Brett T Doherty, Richard K Kwok, Matthew D Curry, Christine Ekenga, David Chambers, Dale P Sandler, Lawrence S Engel
BACKGROUND: Studies of workers exposed to benzene at average air concentrations below one part per million suggest that benzene, a known hematotoxin, causes hematopoietic damage even at low exposure levels. However, evidence of such effects outside of occupational settings and for other volatile organic compounds (VOCs) is limited. OBJECTIVE: To investigate associations between ambient exposures to five VOCs, including benzene, and hematologic parameters among adult residents of the U...
April 26, 2017: Environmental Research
https://www.readbyqxmd.com/read/28399321/septic-arthritis-of-the-wrist-incidence-risk-factors-and-predictors-of-infection
#6
John D Jennings, Elizabeth Zielinski, Rick Tosti, Asif M Ilyas
Septic arthritis of the wrist can result in permanent damage to the joint, making timely diagnosis crucial to initiate empiric antibiotics and surgical intervention. Although septic arthritis is routinely included in the differential diagnosis of atraumatic wrist pain, the incidence is unknown. Unlike large joints, there is no consensus on cell count values considered pathognomonic for wrist septic arthritis. The goal of this retrospective study was to determine the incidence of wrist septic arthritis and to identify the clinical, serum, and joint fluid values that predict infection...
May 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/28369251/white-blood-cell-count-and-total-and-cause-specific-mortality-in-the-women-s-health-initiative
#7
Geoffrey C Kabat, Mimi Y Kim, JoAnn E Manson, Lawrence Lessin, Juan Lin, Sylvia Wassertheil-Smoller, Thomas E Rohan
White blood cell (WBC) count appears to predict total mortality and coronary heart disease (CHD) mortality, but it is unclear to what extent the association reflects confounding by smoking, underlying illness, or comorbid conditions. We used data from the Women's Health Initiative to examine the associations of WBC count with total mortality, CHD mortality, and cancer mortality. WBC count was measured at baseline in 160,117 postmenopausal women and again in year 3 in 74,375 participants. Participants were followed for a mean of 16 years...
March 22, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28360982/joint-effect-of-cigarette-smoking-and-body-mass-index-on-white-blood-cell-count-in-korean-adults
#8
A-Ra Cho, Won-Jun Choi, Shin-Hye Kim, Jae-Yong Shim, Yong-Jae Lee
BACKGROUND: White blood cell count is an independent risk factor for cardiovascular disease. Several lifestyle and metabolic factors such as cigarette smoking and obesity are known to be associated with an elevated white blood cell count. However, the joint effect of cigarette smoking and obesity on white blood cell count has not yet been fully described. METHODS: We explored the joint effect of cigarette smoking and obesity on white blood cell count using multiple logistic regression analyses after adjusting for confounding variables in a population-based, cross-sectional study of 416,065 Korean adults...
March 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/28260878/effect-of-simvastatin-on-mmps-and-timps-in-cigarette-smoke-induced-rat-copd-model
#9
Jiawei Sun, Jie Bao, Yanan Shi, Bin Zhang, Lindong Yuan, Junhong Li, Lihai Zhang, Mo Sun, Ling Zhang, Wuzhuang Sun
BACKGROUND: Proteases may play an important role in the development of chronic obstructive pulmonary disease and emphysema in response to cigarette smoke exposure (CSE). The current study was designed to investigate the expression of matrix metalloproteinase (MMP)-8, MMP-9, MMP-12, tissue inhibitor of MMP (TIMP)-1, and TIMP-4 in rat lung tissues in response to CSE, and assessed the effect of simvastatin in regulating expression of MMPs and TIMPs. METHODS: Thirty normal Sprague Dawley (SD) rats were divided into control (n=10), CSE (n=10), and CSE plus simvastatin (n=10) groups...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28237243/non-small-cell-lung-cancer-patients-with-adenocarcinoma-morphology-have-a-better-outcome-compared-with-patients-diagnosed-with-non-small-cell-lung-cancer-favor-adenocarcinoma
#10
Iris Shiran, Eyal Heller, Shlomit Jessel, Iris Kamer, Inbal Daniel-Meshulam, Rossie Navon, Damien Urban, Amir Onn, Jair Bar
BACKGROUND: Non-small-cell lung cancer (NSCLC) includes 2 major histologic subtypes: squamous cell carcinoma and non-squamous carcinoma, mainly adenocarcinoma, a distinction that carries significant clinical and therapeutic implications. NSCLC is diagnosed as adenocarcinoma or as squamous cell carcinoma on the basis of histologic parameters. However, when morphology is inconclusive, tumors with immunohistochemistry (IHC) findings characteristic of adenocarcinoma are referred to as "NSCLC favor adenocarcinoma" (NFA)...
February 2, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/28213596/white-cell-count-in-the-normal-range-and-short-term-and-long-term-mortality-international-comparisons-of-electronic-health-record-cohorts-in-england-and-new-zealand
#11
Anoop Dinesh Shah, Simon Thornley, Sheng-Chia Chung, Spiros Denaxas, Rod Jackson, Harry Hemingway
OBJECTIVES: Electronic health records offer the opportunity to discover new clinical implications for established blood tests, but international comparisons have been lacking. We tested the association of total white cell count (WBC) with all-cause mortality in England and New Zealand. SETTING: Primary care practices in England (ClinicAl research using LInked Bespoke studies and Electronic health Records (CALIBER)) and New Zealand (PREDICT). DESIGN: Analysis of linked electronic health record data sets: CALIBER (primary care, hospitalisation, mortality and acute coronary syndrome registry) and PREDICT (cardiovascular risk assessments in primary care, hospitalisations, mortality, dispensed medication and laboratory results)...
February 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28211083/the-association-between-periodontitis-and-sleep-duration
#12
Mario Romandini, Gioele Gioco, Giorgio Perfetti, Giorgio Deli, Edoardo Staderini, Andreina Laforì
AIM: Due to its potential to influence systemic inflammation and oxidative stress, and to predispose to bacterial infections, sleep duration could potentially be a risk factor for periodontitis. The aim of this cross-sectional study was to evaluate if there was in 2012 an association between periodontitis and sleep duration in a representative sample of the South Korean population. MATERIALS AND METHODS: A total of 5812 subjects representative of 39.4 million of adults were examined...
February 17, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28194264/agrobacterium-sp-derived-%C3%AE-1-3-glucan-enhances-natural-killer-cell-activity-in-healthy-adults-a-randomized-double-blind-placebo-controlled-parallel-group-study
#13
Yeon Joo Lee, Doo-Jin Paik, Dae Young Kwon, Hye Jeong Yang, Yongsoon Park
BACKGROUND/OBJECTIVES: The present study investigated the hypothesis that a highly pure linear β-1,3-glucan produced by Agrobacterium sp. R259 enhances human natural killer (NK) cell activity and suppresses pro-inflammatory cytokines. SUBJECTS/METHODS: In an eight-week, double-blind, randomized, placebo-controlled clinical trial, 83 healthy adults with white blood cell counts of 4,000-8,000 cells/µL were participated and randomly assigned to take two capsules per day containing either 350 mg β-1,3-glucan or placebo...
February 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28151879/relation-between-tumor-fdg-uptake-and-hematologic-prognostic-indicators-in-stage-i-lung-cancer-patients-following-curative-resection
#14
Eugene Jeong, Seung Hyup Hyun, Seung Hwan Moon, Young Seok Cho, Byung-Tae Kim, Kyung-Han Lee
Hematologic parameters of systemic inflammation are receiving attention as promising prognostic indicators in cancer patients. Here, we investigated the relation and compared the prognostic values of circulating blood cell-based parameters and tumor F-fluoro-2-deoxyglucose (FDG) uptake in patients with stage I nonsmall cell lung cancers (NSCLC).Subjects were 1034 patients with newly diagnosed stage I NSCLC who underwent FDG positron emission tomography/computed tomography (PET/CT) followed by curative resection...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28140379/factors-that-influence-the-volatile-organic-compound-content-in-human-breath
#15
L Blanchet, A Smolinska, A Baranska, E Tigchelaar, M Swertz, A Zhernakova, J W Dallinga, C Wijmenga, F J van Schooten
BACKGROUND: Thousands of endogenous and exogenous volatile organic compounds (VOCs) are excreted in each breath. Inflammatory and deviant metabolic processes affect the level of endogeneous VOCs, which can serve as specific biomarkers for clinical diagnosis and disease monitoring. Important issues that still need to be tackled are related to potential confounding factors like gender and age and endogenous and exogenous factors, like f.i. smoking. METHODS: The aim of this study was to systematically access the effect of endogenous and exogenous factors on VOC composition of exhaled breath...
February 22, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28026133/role-of-increased-mean-platelet-volume-mpv-and-decreased-mpv-platelet-count-ratio-as-poor-prognostic-factors-in-lung-cancer
#16
Muhyettin Omar, Ozgur Tanriverdi, Suna Cokmert, Esin Oktay, Ozlem Yersal, Kezban Nur Pilancı, Serkan Menekse, Muharrem Kocar, Cenk Ahmet Sen, Cetin Ordu, Gamze Goksel, Nezih Meydan, Sabri Barutca
OBJECTIVES: In this study, they investigated whether mean thrombocyte volume (MPV) and MPV/platelet count ratio have a prognostic significance in advanced NSCLC or not. METHODS: A total of 496 NSCLC patients at stage IIIB/IV and did not meet exclusion criteria were included in the study. The demographic features (age, gender, smoking habit), clinical characteristics (performance status, weight loss, disease stage, first-line treatment regimen), laboratory tests (levels of hemoglobin, lactate dehydrogenase and calcium as well as MPV, MPV/platelet count ratio and counts of white blood cell, platelet), and histological features (histologic type, tumor grade) were recorded...
December 27, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28000297/use-of-free-tissue-transfer-in-head-and-neck-cancer-surgery-and-risk-of-overall-and-serious-complication-s-an-american-college-of-surgeons-national-surgical-quality-improvement-project-analysis-of-free-tissue-transfer-to-the-head-and-neck
#17
Steven B Cannady, Kyle M Hatten, Andres M Bur, Jason Brant, John P Fischer, Jason G Newman, Ara A Chalian
BACKGROUND: The purpose of this article was to assess the rates of head and neck free tissue transfer and variables available in the American College of Surgeons - National Surgical Quality Improvement Project (ACS-NSQIP) dataset to predict overall and serious complications. METHODS: We conducted a data analysis from 2005 to 2014 on free tissue cases in the head and neck with descriptive and cross-sectional analysis to examine correlation of NSQIP variables with complications (p < ...
December 21, 2016: Head & Neck
https://www.readbyqxmd.com/read/27992613/the-association-of-resting-heart-rate-with-the-presence-of-diabetes-in-korean-adults-the-2010-2013-korea-national-health-and-nutrition-examination-survey
#18
Jae Won Hong, Jung Hyun Noh, Dong-Jun Kim
BACKGROUND: Previous epidemiologic studies have shown that elevated resting heart rate (HR) is associated with higher cardiovascular disease (CVD) morbidity and mortality. Although the relationship between elevated HR and CVD is well established, the association between resting HR and diabetes has been relatively understudied, particularly in non-Western populations. OBJECTIVES: We confirmed the association between the presence of type 2 diabetes and resting HR in the Korean adult population using data from the 2010-2013 Korea National Health and Nutrition Examination Survey (KNHANES)...
2016: PloS One
https://www.readbyqxmd.com/read/27932354/longitudinal-impact-of-smoking-and-smoking-cessation-on-inflammatory-markers-of-cardiovascular-disease-risk
#19
Cecile C King, Megan E Piper, Adam D Gepner, Michael C Fiore, Timothy B Baker, James H Stein
OBJECTIVE: To evaluate longitudinal changes in 6 inflammatory markers that predict cardiovascular disease events among smokers making a quit attempt and to characterize their cross-sectional associations between smoking and smoking heaviness. APPROACH AND RESULTS: In a longitudinal cohort study of contemporary smokers (n=1652), we evaluated (1) independent associations of smoking heaviness markers (exhaled carbon monoxide, cigarettes/d, pack-years) with inflammatory markers (C-reactive protein, D-dimer, fibrinogen, urinary F2 isoprostane:creatinine [F2:Cr] ratio, white blood cell [WBC] count, myeloperoxidase) and (2) the effects of smoking cessation and continued smoking on these inflammatory markers after 1 year, among the 888 smokers who made an aided quit attempt as part of a randomized comparative effectiveness trial or standard care...
February 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/27893805/association-between-alcohol-intake-and-hemoglobin-a1c-in-the-korean-adults-the-2011-2013-korea-national-health-and-nutrition-examination-survey
#20
Jae Won Hong, Jung Hyun Noh, Dong-Jun Kim
BACKGROUND: Although alcohol consumption is commonly encountered in clinical practice, few studies have investigated the clinical significance of alcohol intake on the use of the hemoglobin A1c (HbA1c) level. OBJECTIVES: This study was performed to investigate the association between alcohol intake and HbA1c level in the general population. METHODS: Among the 24,594 participants who participated in the 2011-2013 Korea National Health and Nutrition Examination Survey (KNHANES), 12,923 participants were analyzed in this study...
2016: PloS One
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