keyword
MENU ▼
Read by QxMD icon Read
search

urine infection

keyword
https://www.readbyqxmd.com/read/28350870/bacterial-clonal-diagnostics-as-a-tool-for-evidence-based-empiric-antibiotic-selection
#1
Veronika Tchesnokova, Hovhannes Avagyan, Elena Rechkina, Diana Chan, Mariya Muradova, Helen Ghirmai Haile, Matthew Radey, Scott Weissman, Kim Riddell, Delia Scholes, James R Johnson, Evgeni V Sokurenko
Despite the known clonal distribution of antibiotic resistance in many bacteria, empiric (pre-culture) antibiotic selection still relies heavily on species-level cumulative antibiograms, resulting in overuse of broad-spectrum agents and excessive antibiotic/pathogen mismatch. Urinary tract infections (UTIs), which account for a large share of antibiotic use, are caused predominantly by Escherichia coli, a highly clonal pathogen. In an observational clinical cohort study of urgent care patients with suspected UTI, we assessed the potential for E...
2017: PloS One
https://www.readbyqxmd.com/read/28345469/the-role-of-estradiol-metabolism-in-urogenital-schistosomiasis-induced-bladder-cancer
#2
Nuno Vale, Maria J Gouveia, Gabriel Rinaldi, Júlio Santos, Lúcio Lara Santos, Paul J Brindley, José M Correia da Costa
Urogenital schistosomiasis is a neglected tropical disease that can lead to bladder cancer. How urogenital schistosomiasis induces carcinogenesis remains unclear, although there is evidence that the human blood fluke Schistosoma haematobium, the infectious agent of urogenital schistosomiasis, releases estradiol-like metabolites. These kind of compounds have been implicated in other cancers. Aiming for enhanced understanding of the pathogenesis of the urogenital schistosomiasis-induced bladder cancer, here we review, interpret, and discuss findings of estradiol-like metabolites detected in both the parasite and in the human urine during urogenital schistosomiasis...
March 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28341758/high-salt-intake-is-associated-with-atrophic-gastritis-with-intestinal-metaplasia
#3
Ji Hyun Song, Young Sun Kim, Nam Ju Heo, Joo Hyun Lim, Sun Young Yang, Goh Eun Chung, Joo Sung Kim
BACKGROUND: Although several studies have investigated excessive salt intake as a risk factor for gastric precancerous lesions such as atrophic gastritis (AG) and intestinal metaplasia (IM), the evidence is insufficient to make conclusion. We evaluated the association between gastric precancerous lesions and salt intake. METHODS: From 2008 to 2015, the medical records of 728 subjects who underwent upper gastrointestinal endoscopy and sodium excretion in 24-hr urine tests were retrospectively reviewed...
March 24, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28341495/a-phase-2-study-of-tmx-101-intravesical-imiquimod-for-the-treatment-of-carcinoma-in-situ-bladder-cancer
#4
Nicholas M Donin, Karim Chamie, Andrew T Lenis, Allan J Pantuck, Madhu Reddy, Dana Kivlin, Johanna Holldack, Rafaella Pozzi, Gil Hakim, Lawrence I Karsh, Donald L Lamm, Laurence H Belkoff, Arie S Belldegrun, Stuart Holden, Neal Shore
PURPOSE: Imiquimod is a toll-like receptor agonist with proven antitumor activity as a topical treatment for skin cancer. TMX-101 (Vesimune) is a novel liquid formulation of imiquimod optimized for intravesical delivery. The agent demonstrated safety as an intravesical treatment for non-muscle-invasive bladder cancer in a phase 1 clinical trial. We report the results of a phase 2 prospective multicenter clinical trial assessing the safety and activity of TMX-101. MATERIALS AND METHODS: Patients with non-muscle-invasive bladder cancer containing carcinoma in situ were eligible for inclusion...
February 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28340803/evaluation-of-ureteral-stent-colonization-in-live-donor-renal-transplant-recipients
#5
M Sarier, M Demir, I Duman, Y Yuksel, A Demirbas
BACKGROUND: Ureteral stent insertion during kidney transplantation is a matter of debate. Stenting has been proven to reduce the risk of surgical complications. In addition, it has been reported to increase risks such as urinary tract infections especially after operation. Ureteral stent colonization (USC) is known to play a role in the pathogenesis of stent related-infections. The aim of this study was (1) to assess the frequency of USC and values of urine cultures in identifying colonizing bacteria; (2) to assess the importance of indwelling time for USC in live-donor renal transplant recipients; and (3) to evaluate the biomarker role of neutrophil-to-lymphocyte ratio (NLR) on USC...
April 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28339443/clinical-outcome-of-augmentation-enterocystoplasty-for-patients-with-ketamine-induced-cystitis
#6
Yu Khun Lee, Jia-Fong Jhang, Hann-Chorng Kuo
BACKGROUND: Ketamine abuse has become a global phenomenon in recent years. Ketamine-induced cystitis (KC) is a new clinical syndrome which can result in severely inflamed bladder and intractable bladder pain. Currently there is no guideline for managing patients with KC. OBJECTIVES: To analyze the clinical outcome of patients with KC managed with augmentation enterocystoplasty (AE). STUDY DESIGN: Retrospective interventional study. SETTING: A tertiary teaching hospital, Hualien Tzu Chi Hospital...
March 2017: Pain Physician
https://www.readbyqxmd.com/read/28337217/cost-effectiveness-analysis-of-helicobacter-pylori-diagnostic-methods-in-patients-with-atrophic-gastritis
#7
Fumio Omata, Takuro Shimbo, Sachiko Ohde, Gautam A Deshpande, Tsuguya Fukui
Background. There are several diagnostic methods for Helicobacter pylori (H. pylori) infection. A cost-effective analysis is needed to decide on the optimal diagnostic method. The aim of this study was to determine a cost-effective diagnostic method in patients with atrophic gastritis (AG). Methods. A decision-analysis model including seven diagnostic methods was constructed for patients with AG diagnosed by esophagogastroduodenoscopy. Expected values of cost and effectiveness were calculated for each test...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28336269/epidemiology-of-polyparasitism-with-taenia-solium-schistosomes-and-soil-transmitted-helminths-in-the-co-endemic-village-of-malanga-democratic-republic-of-congo
#8
Joule Madinga, Katja Polman, Kirezi Kanobana, Lisette van Lieshout, Eric Brienen, Nicolas Praet, Constantin Kabwe, Sarah Gabriël, Pierre Dorny, Pascal Lutumba, Niko Speybroeck
Helminth co-infections are common in sub-Saharan Africa. However, little is known about the distribution and determinants of co-infections with Taenia solium taeniasis/cysticercosis. Building on a previous community-based study on human cysticercosis in Malanga village, we investigated co-infections with Taenia solium, soil-transmitted helminths (STHs) and Schistosoma spp and associated risk factors in a random subsample of 330 participants. Real time PCR assays were used to detect DNA of soil-transmitted helminths (STHs), T...
March 20, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28334777/clinicians-interpretations-of-point-of-care-urine-culture-versus-laboratory-culture-results-analysis-from-the-four-country-poetic-trial-of-diagnosis-of-uncomplicated-urinary-tract-infection-in-primary-care
#9
Saskia Hullegie, Mandy Wootton, Theo J M Verheij, Emma Thomas-Jones, Janine Bates, Kerenza Hood, Micaela Gal, Nick A Francis, Paul Little, Michael Moore, Carl Llor, Timothy Pickles, David Gillespie, Nigel Kirby, Curt Brugman, Christopher C Butler
Background.: Urine culture at the point of care minimises delay between obtaining the sample and agar inoculation in a microbiology laboratory, and quantification and sensitivity results can be available more rapidly in primary care. Objective.: To identify the degree to which clinicians' interpretations of a point-of-care-test (POCT) urine culture (Flexicult™ SSI-Urinary Kit) agrees with laboratory culture in women presenting to primary care with symptoms of uncomplicated urinary tract infections (UTI)...
March 1, 2017: Family Practice
https://www.readbyqxmd.com/read/28333910/establishing-a-timeline-to-discontinue-routine-testing-of-asymptomatic-pregnant-women-for-zika-virus-infection-american-samoa-2016-2017
#10
W Thane Hancock, Heidi M Soeters, Susan L Hills, Ruth Link-Gelles, Mary E Evans, W Randolph Daley, Emily Piercefield, Magele Scott Anesi, Mary Aseta Mataia, Anaise M Uso, Benjamin Sili, Aifili John Tufa, Jacqueline Solaita, Elizabeth Irvin-Barnwell, Dana Meaney-Delman, Jason Wilken, Paul Weidle, Karrie-Ann E Toews, William Walker, Phillip M Talboy, William K Gallo, Nevin Krishna, Rebecca L Laws, Megan R Reynolds, Alaya Koneru, Carolyn V Gould
The first patients with laboratory-confirmed cases of Zika virus disease in American Samoa had symptom onset in January 2016 (1). In response, the American Samoa Department of Health (ASDoH) implemented mosquito control measures (1), strategies to protect pregnant women (1), syndromic surveillance based on electronic health record (EHR) reports (1), Zika virus testing of persons with one or more signs or symptoms of Zika virus disease (fever, rash, arthralgia, or conjunctivitis) (1-3), and routine testing of all asymptomatic pregnant women in accordance with CDC guidance (2,3)(...
March 24, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28333758/cutaneous-burn-injury-modulates-urinary-antimicrobial-peptide-responses-and-the-urinary-microbiome
#11
Jennifer K Plichta, Casey J Holmes, Vanessa Nienhouse, Michelle Puszynski, Xiang Gao, Qunfeng Dong, Huaiying Lin, James Sinacore, Michael Zilliox, Evelyn Toh, David E Nelson, Richard L Gamelli, Katherine A Radek
OBJECTIVES: Characterization of urinary bacterial microbiome and antimicrobial peptides after burn injury to identify potential mechanisms leading to urinary tract infections and associated morbidities in burn patients. DESIGN: Retrospective cohort study using human urine from control and burn subjects. SETTING: University research laboratory. PATIENTS: Burn patients. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Urine samples from catheterized burn patients were collected hourly for up to 40 hours...
March 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28332345/high-incidence-of-virulence-factors-among-clinical-enterococcus-faecalis-isolates-in-southwestern-iran
#12
Hamid Heidari, Somayeh Hasanpour, Hadi Sedigh Ebrahim-Saraie, Mohammad Motamedifar
BACKGROUND: Over the past two decades, enterococci have emerged as an important agent responsible for hospital acquired infection. Several virulence factors contribute to the adherence, colonization, evasion of the host immune response, and pathogenicity and severity of the infection. Enterococcus faecalis is the most common and virulent species causing infections in hospitalized patients. The aim of the present study was to examine the prevalence of genes encoding virulence factors and antimicrobial resistance patterns of E...
March 13, 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/28331290/effects-of-dexamethasone-coadministered-with-oseltamivir-on-the-pharmacokinetics-of-oseltamivir-in-healthy-volunteers
#13
Kyungho Jang, Min-Kyoung Kim, Jaeseong Oh, SeungHwan Lee, Joo-Youn Cho, Kyung-Sang Yu, Tai Kiu Choi, Sang-Hyuk Lee, Kyoung Soo Lim
PURPOSE: Oseltamivir is widely used in the treatment and prophylaxis of influenza A and B viral infections. It is ingested as an oral prodrug that is rapidly metabolized by carboxylesterase 1 (CES1) to its active form, oseltamivir carboxylate. Dexamethasone is also used in the treatment of acute respiratory distress syndrome, a severe complication of influenza; however, its influence on the pharmacokinetics (PK) of oseltamivir is controversial. The aim of this study was to investigate the effects of coadministering oseltamivir and dexamethasone on the PK of oseltamivir in healthy volunteers...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28331086/nectin-4-interactions-govern-measles-virus-virulence-in-a-new-model-of-pathogenesis-squirrel-monkeys-simia-sciureus
#14
Sébastien Delpeut, Bevan Sawatsky, Xiao-Xiang Wong, Marie Frenzke, Roberto Cattaneo, Veronika von Messling
In addition to humans, only certain non-human primates are naturally susceptible to measles virus (MeV) infection. Disease severity is species-dependent, ranging from mild to moderate for macaques to severe and even lethal for certain New World monkey species. To investigate if squirrel monkeys (Simia sciureus), which are reported to develop a course of disease similar to humans, may be better suited than macaques for the identification of virulence determinants or the evaluation of therapeutics, we infected them with a green fluorescent protein-expressing MeV...
March 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28330863/bacterial-virulence-phenotypes-of-escherichia-coli-and-host-susceptibility-determine-risk-for-urinary-tract-infections
#15
Henry L Schreiber, Matt S Conover, Wen-Chi Chou, Michael E Hibbing, Abigail L Manson, Karen W Dodson, Thomas J Hannan, Pacita L Roberts, Ann E Stapleton, Thomas M Hooton, Jonathan Livny, Ashlee M Earl, Scott J Hultgren
Urinary tract infections (UTIs) are caused by uropathogenic Escherichia coli (UPEC) strains. In contrast to many enteric E. coli pathogroups, no genetic signature has been identified for UPEC strains. We conducted a high-resolution comparative genomic study using E. coli isolates collected from the urine of women suffering from frequent recurrent UTIs. These isolates were genetically diverse and varied in their urovirulence, that is, their ability to infect the bladder in a mouse model of cystitis. We found no set of genes, including previously defined putative urovirulence factors (PUFs), that were predictive of urovirulence...
March 22, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28330498/identification-of-cattle-buffaloes-and-rodents-as-reservoir-animals-of-leptospira-in-the-district-of-gampaha-sri-lanka
#16
D T H Denipitiya, N V Chandrasekharan, W Abeyewickreme, R A Hartskeerl, M D Hapugoda
BACKGROUND: Leptospirosis is an important emerging infectious disease in Sri Lanka. Rats are the most important reservoir of Leptospira but domestic and wild mammals may also act as important maintenance or accidental hosts. In Sri Lanka, knowledge of reservoir animals of leptospires is poor. The objective of this study was to identify potential reservoir animals of Leptospira in the District of Gampaha, Sri Lanka. FINDINGS: Blood and kidney samples were collected from 38 rodents and mid-stream urine samples were randomly collected from 45 cattle and five buffaloes in the District of Gampaha...
March 23, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28329941/-genital-chlamydia-trachomatis-infection-and-associated-risk-factors-in-male-clients-attending-sexually-transmitted-disease-clinics-in-9-cities-in-guangdong-province
#17
H C Shen, S J Huang, X L Qin, P Z Zhao, Y Y Lan, H C Zou, J L Ou, L Chen, X M Luo, H P Zheng, Y Li, B Yang
Objective: To investigate the prevalence of genital Chlamydia trachomatis (GCT) infection and associated risk factors in male clients attending sexually transmitted disease (STD) clinics in Guangdong and provide integrated intervention strategy for this group. Methods: Convenient sampling was used to recruit participants from April to June in 2015 in Guangdong province. The information about their socio-demographic characteristics and sexual behaviors were collected by using a questionnaire, and blood samples were taken from them to test the antibodies against HIV, syphilis and HCV...
March 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28328351/natural-infection-of-leptospira-species-in-the-native-rodents-degu-octodon-degus-and-darwin-s-pericote-phyllotis-darwini-in-mediterranean-ecosystem-of-chile
#18
Juana Paola Correa, Antonella Bacigalupo, Carezza Botto-Mahan, Sergio Bucarey, Pedro Eduardo Cattan, Rodrigo García de Cortázar, Carlos Landaeta-Aqueveque, Juan Ramírez-Estrada
We report natural infections by pathogenic Leptospira of two rodent species endemic to Chile: the degu ( Octodon degus ) and Darwin's pericote ( Phyllotis darwini ). We detected Leptospira DNA in kidney and urine samples taken in different years and sites, reaching 33% infection. The effects of infection in these species requires further evaluation.
March 22, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28327780/-leptospira-infections-in-cats
#19
Sonia Weis, Katrin Hartmann
Leptospirosis is a widespread zoonosis found in over 150 mammalian species. Subclinically infected rodents and farm animals serve as reservoir hosts. Cats are exposed to leptospires regularly, particularly through hunting infected rodents. However, clinical leptospirosis is rare in cats. Nevertheless, infected cats can shed the pathogen through urine and thus, cats could play an important role in the epidemiology of leptospires.
March 22, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28327187/schistosomiasis-is-more-prevalent-than-previously-thought-what-does-it-mean-for-public-health-goals-policies-strategies-guidelines-and-intervention-programs
#20
REVIEW
Daniel G Colley, Tamara S Andros, Carl H Campbell
Mapping and diagnosis of infections by the three major schistosome species (Schistosoma haematobium, S. mansoni and S. japonicum) has been done with assays that are known to be specific but increasingly insensitive as prevalence declines or in areas with already low prevalence of infection. This becomes a true challenge to achieving the goal of elimination of schistosomiasis because the multiplicative portion of the life-cycle of schistosomes, in the snail vector, favors continued transmission as long as even a few people maintain low numbers of worms that pass eggs in their excreta...
March 22, 2017: Infectious Diseases of Poverty
keyword
keyword
84727
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"