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https://www.readbyqxmd.com/read/29343948/types-and-delivery-of-emotional-support-to-promote-linkage-and-engagement-in-hiv-care
#1
Christa L Cook, Shantrel Canidate, Nicole Ennis, Robert L Cook
Purpose: Despite recommendations for early entry into human immunodeficiency virus (HIV) care, many people diagnosed with HIV delay seeking care. Multiple types of social support (ie, cognitive, emotional, and tangible) are often needed for someone to transition into HIV care, but a lack of emotional support at diagnosis may be the reason why some people fail to stay engaged in care. Thus, the purpose of this study was to identify how people living with HIV conceptualized emotional support needs and delivery at diagnosis...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29339579/conclusions-and-recommendations-from-the-17th-workshop-of-the-european-alara-network-alara-in-emergency-exposure-situations
#2
Sylvain Andresz, Julie Morgan, Pascal Croüail, Fernand Vermeersch
The European ALARA Network regularly organises workshops on topical issues in radiation protection. In light of the Fukushima accident, the most recent workshop questioned the application of the ALARA principle in emergency exposures situations. This memorandum presents the conclusions and recommendations of this workshop. One of the outcomes is that the process of optimisation in emergency exposure situations should be flexible enough to be able to modify or refine decisions over the course of an accident...
January 17, 2018: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
https://www.readbyqxmd.com/read/29337291/realization-of-half-metallic-state-on-bilayer-wse2-by-doping-transition-metals-cr-mn-fe-co-ni-in-its-interlayer
#3
Guang Yang, Yanmin Yang, Hongran Ma, Xiujuan Mao, Congcong Li, Jie Li, Qiang Zhang, Zhidong Zhang, Fuxing Yin, Jia Li
The structural, electronic and magnetic properties of Cr, Mn, Fe, Co and Ni-doped bilayer WSe2 are predicted by using first principles calculations. The doped transition-metal atoms show a covalent-binding with the nearest Se atoms. The calculated electronic structures reveal that the transition metal Cr, Mn, Fe and Co-doped bilayer WSe2 exhibit the half-metallic character with a 100% spin polarization at the Fermi level, and the reason is ascribed to the strong hybridization peak between the transition metals and parent W and Se atoms...
January 16, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29334802/youth-and-young-adults-with-acquired-brain-injury-transition-towards-work-related-roles-a-qualitative-study
#4
Alicia Paniccia, Heather Colquhoun, Bonnie Kirsh, Sally Lindsay
PURPOSE: The purpose of this research was to explore the experiences of youth and young adults with acquired brain injury as they transition towards work-related roles. Little is known about employment experiences among this age group. Understanding their perspectives can inform programs and clinical practice. MATERIALS AND METHODS: A descriptive qualitative design, including semi-structured interviews with 14 participants (8 females; 6 males) was used. Interviews were transcribed verbatim and analyzed using an open-coding, thematic approach...
January 15, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29328404/chronic-oxymatrine-treatment-induces-resistance-and-epithelial%C3%A2-mesenchymal-transition-through-targeting-the-long-non-coding-rna-malat1-in-colorectal-cancer-cells
#5
Yibai Xiong, Jun Wang, Huirong Zhu, Lingshuang Liu, Yi Jiang
A major reason for colorectal cancer (CRC) chemoresistance is the enhanced migration and invasion of cancer cells, such as the cell acquisition of epithelial-mesenchymal transition (EMT). Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been considered as a pro-oncogene in multiple cancers. However, the precise functional mechanism of lncRNA MALAT1 in chemoresistance and EMT is not well known. In the present study, we focused on the effect of oxymatrine on CRC cells and further investigated the role of MALAT1 in oxymatrine-induced resistance and EMT process...
January 10, 2018: Oncology Reports
https://www.readbyqxmd.com/read/29323916/influence-of-eugenol-on-the-organization-and-dynamics-of-lipid-membranes-a-phase-dependent-study
#6
Geetanjali Meher, Hirak Chakraborty
Eugenol is known for its antimicrobial effects against microorganisms responsible for infectious diseases in human, food borne pathogens and oral pathogens. In spite of several reports on the antimicrobial function of eugenol by modulating the structural properties of cell membrane there was no direct information on the influence of eugenol in the lipid membrane. In this work, we explored the effect of eugenol on organization and dynamics of large unilamellar vesicles (LUVs) of DMPC using the intrinsic fluorescence of eugenol and an extrinsic hydrophobic probe, DPH, in varying phases...
January 11, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29323367/quantitative-mass-spectrometry-imaging-of-glutathione-in-healthy-and-cancerous-hen-ovarian-tissue-sections-by-infrared-matrix-assisted-laser-desorption-electrospray-ionization-ir-maldesi
#7
Milad Nazari, Mark T Bokhart, Philip L Loziuk, David C Muddiman
A quantitative mass spectrometry imaging (QMSI) method for absolute quantification of glutathione (GSH) in healthy and cancerous hen ovarian tissues using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) is presented. Using this technique, the ion abundance of GSH was normalized to that of a structural analogue, which was sprayed on the slide prior to mounting the tissue sections. This normalization strategy significantly improved the voxel-to-voxel variability; the variability is attributed to the overall ionization process...
January 11, 2018: Analyst
https://www.readbyqxmd.com/read/29320449/changing-trends-in-nutritional-behavior-among-university-students-in-greece-between-2006-and-2016
#8
Charikleia Kyrkou, Foteini Tsakoumaki, Maria Fotiou, Aristea Dimitropoulou, Maria Symeonidou, Georgios Menexes, Costas G Biliaderis, Alexandra-Maria Michaelidou
The objective of the present survey was to study the dietary behavior of university students residing away from the family home. In this context, we (a) compared their dietary habits in two time periods, namely 2006 and 2016; and (b) explored the possible impact of gender on the behavioral changes in nutritional choices. A total of four hundred and five university students (2006, n = 242; 2016, n = 163) participated in the study. Dietary assessment was carried out using a qualitative Food Frequency Questionnaire, while data about demographic and lifestyle factors were also collected...
January 10, 2018: Nutrients
https://www.readbyqxmd.com/read/29316621/development-of-coarse-grained-liquid-crystal-polymer-model-with-efficient-electrostatic-interaction-toward-molecular-dynamics-simulations-of-electroactive-materials
#9
Kenji Tagashira, Kazuaki Z Takahashi, Jun-Ichi Fukuda, Takeshi Aoyagi
Liquid-crystal polymers (LCPs) are well known materials for functional sensor and actuators, because of their high-responsiveness to an electric field. Owing to their complex physical nature, however, the prediction of the functions of LCPs is a challenge. To attack this problem from a molecular point of view, a simulation study is a promising approach. In this work, for future applications of molecular dynamics simulations to problems involving an electric field, we develop an LCP model which consists of coarse-grained mesogenic molecules and smeared charges...
January 6, 2018: Materials
https://www.readbyqxmd.com/read/29301382/hydrogen-bonds-and-life-in-the-universe
#10
Giovanni Vladilo, Ali Hassanali
The scientific community is allocating more and more resources to space missions and astronomical observations dedicated to the search for life beyond Earth. This experimental endeavor needs to be backed by a theoretical framework aimed at defining universal criteria for the existence of life. With this aim in mind, we have explored which chemical and physical properties should be expected for life possibly different from the terrestrial one, but similarly sustained by genetic and catalytic molecules. We show that functional molecules performing genetic and catalytic tasks must feature a hierarchy of chemical interactions operating in distinct energy bands...
January 3, 2018: Life
https://www.readbyqxmd.com/read/29296905/sociodemographic-factors-in-patients-continuing-warfarin-vs-those-transitioning-to-direct-oral-anticoagulants
#11
Jordan K Schaefer, Suman L Sood, Brian Haymart, Xiaokui Gu, Xiaowen Kong, Eva Kline-Rogers, Steven Almany, Jay Kozlowski, Gregory D Krol, Scott Kaatz, James B Froehlich, Geoffrey D Barnes
Clinical factors and patient preferences are important for selecting oral anticoagulants for venous thromboembolism (VTE) and atrial fibrillation (AF). The relative association of sociodemographic factors with anticoagulant use is unknown. We evaluated a prospective cohort to compare sociodemographic variables in patients who continued on warfarin for AF or VTE to those who transitioned to 1 of the direct oral anticoagulants (DOACs). Adult patients, newly started on warfarin, were enrolled through 6 anticoagulation clinics across Michigan...
December 12, 2017: Blood Advances
https://www.readbyqxmd.com/read/29284487/review-of-journal-of-cardiovascular-magnetic-resonance-jcmr-2015-2016-and-transition-of-the-jcmr-office-to-boston
#12
REVIEW
Warren J Manning
The Journal of Cardiovascular Magnetic Resonance (JCMR) is the official publication of the Society for Cardiovascular Magnetic Resonance (SCMR). In 2016, the JCMR published 93 manuscripts, including 80 research papers, 6 reviews, 5 technical notes, 1 protocol, and 1 case report. The number of manuscripts published was similar to 2015 though with a 12% increase in manuscript submissions to an all-time high of 369. This reflects a decrease in the overall acceptance rate to <25% (excluding solicited reviews)...
December 28, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29282069/health-system-s-response-for-physician-workforce-shortages-and-the-upcoming-crisis-in-ethiopia-a-grounded-theory-research
#13
Tsion Assefa, Damen Haile Mariam, Wubegzier Mekonnen, Miliard Derbew
BACKGROUND: A rapid transition from severe physician workforce shortage to massive production to ensure the physician workforce demand puts the Ethiopian health care system in a variety of challenges. Therefore, this study discovered how the health system response for physician workforce shortage using the so-called flooding strategy was viewed by different stakeholders. METHODS: The study adopted the grounded theory research approach to explore the causes, contexts, and consequences (at the present, in the short and long term) of massive medical student admission to the medical schools on patient care, medical education workforce, and medical students...
December 28, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/29279186/digital-dermatitis-in-dairy-cattle-the-contribution-of-different-disease-classes-to-transmission
#14
Floor Biemans, Piter Bijma, Natasja M Boots, Mart C M de Jong
Digital Dermatitis (DD) is a claw disease mainly affecting the hind feet of dairy cattle. Digital Dermatitis is an infectious disease, transmitted via the environment, where the infectious "agent" is a combination of bacteria. The standardized classification for DD lesions developed by Döpfer et al. (1997) and extended by Berry et al. (2012) has six distinct classes: healthy (M0), an active granulomatous area of 0-2 cm (M1), an ulcerative lesion of >2 cm (M2), an ulcerative lesion covered by a scab (M3), alteration of the skin (M4), and a combination of M4 and M1 (M4...
December 22, 2017: Epidemics
https://www.readbyqxmd.com/read/29278847/analysis-of-the-wuschel-related-homeobox-gene-family-in-pinus-pinaster-new-insights-into-the-gene-family-evolution
#15
José M Alvarez, Natalia Bueno, Rafael A Cañas, Concepción Avila, Francisco M Cánovas, Ricardo J Ordás
WUSCHEL-RELATED HOMEOBOX (WOX) genes are key players controlling stem cells in plants and can be divided into three clades according to the time of their appearance during plant evolution. Our knowledge of stem cell function in vascular plants other than angiosperms is limited, they separated from gymnosperms ca 300 million years ago and their patterning during embryogenesis differs significantly. For this reason, we have used the model gymnosperm Pinus pinaster to identify WOX genes and perform a thorough analysis of their gene expression patterns...
December 21, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29278826/transitioning-from-phosphate-mining-to-agriculture-responses-to-urea-and-slow-release-fertilizers-for-sorghum-bicolor
#16
Katinka X Ruthrof, Emma Steel, Sunil Misra, Jen McComb, Graham O'Hara, Giles E St J Hardy, John Howieson
Globally, land-use transition from mining to agriculture is becoming increasingly attractive and necessary for many reasons. However, low levels of necessary plant nutrients, and high levels of heavy metals, can hamper plant growth, affecting yield, and potentially, food safety. In post-phosphate mining substrates, for example, nitrogen (N) is a key limiting nutrient, and, although legumes are planted prior to cereals, N supplementation is still necessary. We undertook two field trials on Christmas Island, Australia, to determine whether Sorghum bicolor could be grown successfully in a post-phosphate mining substrate...
December 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29272927/electron-detachment-of-hydrogen-anion-in-collisions-with-hydrogen-molecule-studied-by-surface-hopping-classical-trajectory-calculations
#17
A K Belyaev, A S Tiukanov, A I Toropkin, O V Alexandrovich
We employ the on-the-fly surface hopping classical trajectory algorithm to study the electron detachment process in low-energy H- + H2 collisions. The ground-state and the first-excited-state Local Complex Potentials (LCPs) calculated by the generalized diatomics-in-molecule method are used for the full three-dimensional nonadiabatic nuclear dynamics. Two kinds of nonadiabatic effects are taken into account: discrete-discrete transitions and discrete-continuous transitions. Discrete-discrete nonadiabatic transition probabilities are calculated by means of the adiabatic-potential-based formula within the Landau-Zener model for each individual trajectory computed along real parts of the LCPs...
December 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29261241/insurance-switching-and-mismatch-between-the-costs-and-benefits-of-new-technologies
#18
David Cutler, Michael Ciarametaro, Genia Long, Noam Kirson, Robert Dubois
OBJECTIVES: Many therapies have immediate costs but delayed benefits. Recent and anticipated transformative therapies may exacerbate these challenges. This study explored whether disconnects between short-term budget impacts and long-term costs and benefits, and among impacts on initial payers, downstream payers, and society, are expected for a range of such therapies and whether they are likely consistent or variable, with implications for potential policy responses. STUDY DESIGN: Modeling...
December 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/29260929/switching-basal-insulins-in-type-2-diabetes-practical-recommendations-for-health-care-providers
#19
Sarah L Anderson, Jennifer M Trujillo, John E Anderson, Robert J Tanenberg
Basal insulin remains the mainstay of treatment of type 2 diabetes when diet changes and exercise in combination with oral drugs and other injectable agents are not sufficient to control hyperglycemia. Insulin therapy should be individualized, and several factors influence the choice of basal insulin; these include pharmacological properties, patient preferences, and lifestyle, as well as health insurance plan formularies. The recent availability of basal insulin formulations with longer durations of action has provided further dosing flexibility; however, patients may need to switch agents throughout therapy for a variety of personal, clinical, or economic reasons...
December 20, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/29260179/prospects-for-efficient-solar-energy-upconversion-using-metalloporphyrins-as-dual-absorber-upconverters
#20
Ronald P Steer
The novel potential use of selected metalloporphyrins as dual absorber-upconverters in solar photovoltaics is discussed. Additional efficiencies are available if use can be made of the porphyrin's short-lived S2 state, which is formed directly by excitation in the strong Soret transition in the blue-violet and also by absorption in the Q bands followed by rapid intersystem crossing and upconversion by triplet-triplet annihilation. The main challenge in realizing a working photovoltaic based on such a protocol is that energy must be extracted from the S2 state of the porphyrin within its picosecond lifetime...
December 20, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
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